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April M. Kloxin, Ph.D. - Publications

Affiliations: 
2009 Chemical Engineering University of Colorado, Boulder, Boulder, CO, United States 
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57 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Blache U, Ford EM, Ha B, Rijns L, Chaudhuri O, Dankers PYW, Kloxin AM, Snedeker JG, Gentleman E. Engineered hydrogels for mechanobiology. Nature Reviews. Methods Primers. 2: 98. PMID 37461429 DOI: 10.1038/s43586-022-00179-7  0.38
2021 Wiley KL, Sutherland BP, Ogunnaike BA, Kloxin AM. Rational Design of Hydrogel Networks with Dynamic Mechanical Properties to Mimic Matrix Remodeling. Advanced Healthcare Materials. e2101947. PMID 34936227 DOI: 10.1002/adhm.202101947  0.369
2020 Locke RC, Ford E, Silbernagel KG, Kloxin A, Killian ML. Success Criteria and Preclinical Testing of Multifunctional Hydrogels for Tendon Regeneration. Tissue Engineering. Part C, Methods. PMID 32988293 DOI: 10.1089/ten.TEC.2020.0199  0.384
2020 Sutherland BP, LeValley PJ, Bischoff DJ, Kloxin AM, Kloxin CJ. Sequence-defined vinyl sulfonamide click nucleic acids (VS-CNAs) and their assembly into dynamically responsive materials. Chemical Communications (Cambridge, England). PMID 32820777 DOI: 10.1039/D0Cc04235H  0.318
2020 Wodzanowski KA, Cassel SE, Grimes CL, Kloxin AM. Tools for probing host-bacteria interactions in the gut microenvironment: From molecular to cellular levels. Bioorganic & Medicinal Chemistry Letters. 30: 127116. PMID 32223923 DOI: 10.1016/J.Bmcl.2020.127116  0.386
2020 LeValley PJ, Neelarapu R, Sutherland B, Dasgupta S, Kloxin CJ, Kloxin AM. Photolabile linkers: exploiting labile bond chemistry to control mode and rate of hydrogel degradation and protein release. Journal of the American Chemical Society. PMID 32037819 DOI: 10.1021/Jacs.9B11564  0.444
2019 Smithmyer ME, Cassel SE, Kloxin AM. Bridging 2D and 3D culture: probing impact of extracellular environment on fibroblast activation in layered hydrogels. Aiche Journal. American Institute of Chemical Engineers. 65. PMID 32921797 DOI: 10.1002/Aic.16837  0.405
2019 LeValley PJ, Kloxin AM. Chemical Approaches to Dynamically Modulate the Properties of Synthetic Matrices. Acs Macro Letters. 8: 7-16. PMID 32405440 DOI: 10.1021/Acsmacrolett.8B00808  0.498
2019 Wiley KL, Ovadia EM, Calo CJ, Huber RE, Kloxin AM. Rate-based approach for controlling the mechanical properties of 'thiol-ene' hydrogels formed with visible light. Polymer Chemistry. 10: 4428-4440. PMID 32405326 DOI: 10.1039/C9Py00447E  0.44
2019 Hilderbrand AM, Ford EM, Guo C, Sloppy JD, Kloxin AM. Hierarchically structured hydrogels utilizing multifunctional assembling peptides for 3D cell culture. Biomaterials Science. PMID 31854388 DOI: 10.1039/C9Bm01894H  0.504
2019 Marusina AI, Merleev AA, Luna JI, Olney L, Haigh NE, Yoon D, Guo C, Ovadia EM, Shimoda M, Luxardi G, Boddu S, Lal NN, Takada Y, Lam KS, Liu R, ... ... Kloxin AM, et al. Tunable hydrogels for mesenchymal stem cell delivery: integrin-induced transcriptome alterations and hydrogel optimization for human wound healing. Stem Cells (Dayton, Ohio). PMID 31648388 DOI: 10.1002/Stem.3105  0.493
2019 Bisht J, LeValley P, Noren B, McBride R, Kharkar P, Kloxin A, Gatlin J, Oakey J. Light-inducible activation of cell cycle progression in Xenopus egg extracts under microfluidic confinement. Lab On a Chip. PMID 31544194 DOI: 10.1039/C9Lc00569B  0.408
2018 Smithmyer ME, Deng CC, Cassel SE, LeValley PJ, Sumerlin BS, Kloxin AM. Self-healing boronic acid-based hydrogels for 3D co-cultures. Acs Macro Letters. 7: 1105-1110. PMID 32832198 DOI: 10.1021/Acsmacrolett.8B00462  0.502
2018 Smithmyer ME, Spohn JB, Kloxin AM. Probing fibroblast activation in response to extracellular cues with whole protein- or peptide-functionalized step-growth hydrogels. Acs Biomaterials Science & Engineering. 4: 3304-3316. PMID 32494587 DOI: 10.1021/Acsbiomaterials.8B00491  0.457
2018 LeValley PJ, Noren B, Kharkar PM, Kloxin AM, Gatlin JC, Oakey JS. Fabrication of Functional Biomaterial Microstructures by in Situ Photopolymerization and Photodegradation. Acs Biomaterials Science & Engineering. 4: 3078-3087. PMID 31984222 DOI: 10.1021/Acsbiomaterials.8B00350  0.373
2018 LeValley PJ, Tibbitt MW, Noren B, Kharkar P, Kloxin AM, Anseth KS, Toner M, Oakey J. Immunofunctional photodegradable poly(ethylene glycol) hydrogel surfaces for the capture and release of rare cells. Colloids and Surfaces. B, Biointerfaces. 174: 483-492. PMID 30497010 DOI: 10.1016/J.Colsurfb.2018.11.049  0.734
2018 LeValley PJ, Ovadia EM, Bresette CA, Sawicki LA, Maverakis E, Bai S, Kloxin AM. Design of functionalized cyclic peptides through orthogonal click reactions for cell culture and targeting applications. Chemical Communications (Cambridge, England). PMID 29863200 DOI: 10.1039/C8Cc03218A  0.382
2018 Macdougall LJ, Wiley KL, Kloxin AM, Dove AP. De1sign of synthetic extracellular matrices for probing breast cancer cell growth using robust cyctocompatible nucleophilic thiol-yne addition chemistry. Biomaterials. PMID 29773227 DOI: 10.1016/J.Biomaterials.2018.04.046  0.537
2018 Ovadia EM, Colby DW, Kloxin AM. Designing well-defined photopolymerized synthetic matrices for three-dimensional culture and differentiation of induced pluripotent stem cells. Biomaterials Science. PMID 29675520 DOI: 10.1039/C8Bm00099A  0.465
2018 Sawicki LA, Choe LH, Wiley KL, Lee KH, Kloxin AM. Isolation and Identification of Proteins Secreted by Cells Cultured within Synthetic Hydrogel-Based Matrices. Acs Biomaterials Science & Engineering. 4: 836-845. PMID 29552635 DOI: 10.1021/Acsbiomaterials.7B00647  0.463
2018 Smith NJ, Rohlfing K, Sawicki LA, Kharkar PM, Boyd SJ, Kloxin AM, Fox JM. Fast, irreversible modification of cysteines through strain releasing conjugate additions of cyclopropenyl ketones. Organic & Biomolecular Chemistry. PMID 29521395 DOI: 10.1039/C8Ob00166A  0.302
2018 Kloxin A, Sawicki L, Ovadia E. Abstract P5-03-07: Probing breast cancer cell activation in response to extracellular cues using well-defined synthetic microenvironments Cancer Research. 78. DOI: 10.1158/1538-7445.Sabcs17-P5-03-07  0.432
2017 Kharkar PM, Scott RA, Olney LP, LeValley PJ, Maverakis E, Kiick KL, Kloxin AM. Controlling the Release of Small, Bioactive Proteins via Dual Mechanisms with Therapeutic Potential. Advanced Healthcare Materials. PMID 29024487 DOI: 10.1002/Adhm.201700713  0.412
2017 Rehmann MS, Skeens KM, Kharkar PM, Ford E, Maverakis E, Lee KH, Kloxin AM. Tuning and predicting mesh size and protein release from step growth hydrogels. Biomacromolecules. PMID 28850788 DOI: 10.1021/Acs.Biomac.7B00781  0.36
2017 Guo C, Kim H, Ovadia EM, Mourafetis CM, Yang M, Chen W, Kloxin AM. Bio-orthogonal conjugation and enzymatically triggered release of proteins within multi-layered hydrogels. Acta Biomaterialia. PMID 28391052 DOI: 10.1016/J.Actbio.2017.04.002  0.405
2016 Hilderbrand AM, Ovadia EM, Rehmann MS, Kharkar PM, Guo C, Kloxin AM. Biomaterials for 4D stem cell culture. Current Opinion in Solid State & Materials Science. 20: 212-224. PMID 28717344 DOI: 10.1016/J.Cossms.2016.03.002  0.517
2016 Kharkar PM, Rehmann MS, Skeens KM, Maverakis E, Kloxin AM. Thiol-ene click hydrogels for therapeutic delivery. Acs Biomaterials Science & Engineering. 2: 165-179. PMID 28361125 DOI: 10.1021/Acsbiomaterials.5B00420  0.425
2016 Sawicki LA, Kloxin AM. Light-mediated Formation and Patterning of Hydrogels for Cell Culture Applications. Journal of Visualized Experiments : Jove. PMID 27768057 DOI: 10.3791/54462  0.517
2016 Kloxin A, Lee K. Editorial overview: Tissue, cell and pathway engineering. Current Opinion in Biotechnology. PMID 27426228 DOI: 10.1016/J.Copbio.2016.06.004  0.351
2016 Rehmann MS, Luna JI, Maverakis E, Kloxin AM. Tuning microenvironment modulus and biochemical composition promotes human mesenchymal stem cell tenogenic differentiation. Journal of Biomedical Materials Research. Part A. PMID 26748903 DOI: 10.1002/Jbm.A.35650  0.461
2015 Kharkar PM, Kiick KL, Kloxin AM. Design of Thiol- and Light-sensitive Degradable Hydrogels using Michael-type Addition Reactions. Polymer Chemistry. 6: 5565-5574. PMID 26284125 DOI: 10.1039/C5Py00750J  0.405
2014 Kharkar PM, Kloxin AM, Kiick KL. Dually degradable click hydrogels for controlled degradation and protein release. Journal of Materials Chemistry. B, Materials For Biology and Medicine. 2: 5511-5521. PMID 25908977 DOI: 10.1039/C4Tb00496E  0.431
2014 Sawicki LA, Kloxin AM. Design of thiol-ene photoclick hydrogels using facile techniques for cell culture applications†Electronic supplementary information (ESI) available. See DOI: 10.1039/c4bm00187gClick here for additional data file. Biomaterials Science. 2: 1612-1626. PMID 25717375 DOI: 10.1039/C4Bm00187G  0.557
2014 Fischer P, Tibbitt M, Kloxin A, Anseth K, Oakey J. Photodegradable hydrogels for selective capture and release of Mammalian cells. Biomedical Sciences Instrumentation. 50: 62-7. PMID 25405405  0.709
2014 Smithmyer ME, Sawicki LA, Kloxin AM. Hydrogel scaffolds as in vitro models to study fibroblast activation in wound healing and disease. Biomaterials Science. 2: 634-650. PMID 25379176 DOI: 10.1039/C3Bm60319A  0.458
2014 Fischer P, Tibbitt M, Gatlin JC, Kloxin A, Anseth K, Oakey J. Antibody functionalized micropatterned hydrogels 18th International Conference On Miniaturized Systems For Chemistry and Life Sciences, Microtas 2014. 2512-2513.  0.631
2013 McKinnon DD, Kloxin AM, Anseth KS. Synthetic hydrogel platform for three-dimensional culture of embryonic stem cell-derived motor neurons. Biomaterials Science. 1: 460-469. PMID 32482009 DOI: 10.1039/C3Bm00166K  0.742
2013 Rehmann MS, Garibian AC, Kloxin AM. Hydrolytically degradable thiol-ene hydrogels for protein release. Macromolecular Symposia. 329: 58-65. PMID 25309103 DOI: 10.1002/Masy.201200133  0.38
2013 Tibbitt MW, Kloxin AM, Anseth KS. Modeling Controlled Photodegradation in Optically Thick Hydrogels. Journal of Polymer Science. Part a, Polymer Chemistry. 51: 1899-1911. PMID 24496479 DOI: 10.1002/Pola.26574  0.723
2013 Tibbitt MW, Kloxin AM, Sawicki L, Anseth KS. Mechanical Properties and Degradation of Chain and Step Polymerized Photodegradable Hydrogels. Macromolecules. 46. PMID 24496435 DOI: 10.1021/Ma302522X  0.732
2013 Rehmann MS, Kloxin AM. Tunable and dynamic soft materials for three-dimensional cell culture. Soft Matter. 9: 6737-6746. PMID 23930136 DOI: 10.1039/C3Sm50217A  0.481
2013 Kharkar PM, Kiick KL, Kloxin AM. Designing degradable hydrogels for orthogonal control of cell microenvironments. Chemical Society Reviews. 42: 7335-72. PMID 23609001 DOI: 10.1039/C3Cs60040H  0.553
2013 McKinnon DD, Kloxin AM, Anseth KS. Synthetic hydrogel platform for three-dimensional culture of embryonic stem cell-derived motor neurons Biomaterials Science. 1: 460-469. DOI: 10.1039/c3bm00166k  0.707
2012 Kloxin AM, Lewis KJ, DeForest CA, Seedorf G, Tibbitt MW, Balasubramaniam V, Anseth KS. Responsive culture platform to examine the influence of microenvironmental geometry on cell function in 3D. Integrative Biology : Quantitative Biosciences From Nano to Macro. 4: 1540-9. PMID 23138879 DOI: 10.1039/C2Ib20212C  0.805
2012 Wang H, Haeger SM, Kloxin AM, Leinwand LA, Anseth KS. Redirecting valvular myofibroblasts into dormant fibroblasts through light-mediated reduction in substrate modulus. Plos One. 7: e39969. PMID 22808079 DOI: 10.1371/Journal.Pone.0039969  0.569
2012 Tibbitt MW, Han BW, Kloxin AM, Anseth KS. Student award for outstanding research winner in the Ph.D. category for the 9th World Biomaterials Congress, Chengdu, China, June 1-5, 2012: synthesis and application of photodegradable microspheres for spatiotemporal control of protein delivery. Journal of Biomedical Materials Research. Part A. 100: 1647-54. PMID 22447635 DOI: 10.1002/Jbm.A.34107  0.737
2010 Tibbitt MW, Kloxin AM, Dyamenahalli KU, Anseth KS. Controlled two-photon photodegradation of PEG hydrogels to study and manipulate subcellular interactions on soft materials. Soft Matter. 6: 5100-5108. PMID 21984881 DOI: 10.1039/C0Sm00174K  0.766
2010 Kloxin AM, Tibbitt MW, Anseth KS. Synthesis of photodegradable hydrogels as dynamically tunable cell culture platforms. Nature Protocols. 5: 1867-87. PMID 21127482 DOI: 10.1038/Nprot.2010.139  0.768
2010 Kloxin AM, Kloxin CJ, Bowman CN, Anseth KS. Mechanical properties of cellularly responsive hydrogels and their experimental determination. Advanced Materials (Deerfield Beach, Fla.). 22: 3484-94. PMID 20473984 DOI: 10.1002/Adma.200904179  0.724
2010 Kloxin AM, Tibbitt MW, Kasko AM, Fairbairn JA, Anseth KS. Tunable hydrogels for external manipulation of cellular microenvironments through controlled photodegradation. Advanced Materials (Deerfield Beach, Fla.). 22: 61-6. PMID 20217698 DOI: 10.1002/Adma.200900917  0.775
2010 Kloxin AM, Benton JA, Anseth KS. In situ elasticity modulation with dynamic substrates to direct cell phenotype. Biomaterials. 31: 1-8. PMID 19788947 DOI: 10.1016/J.Biomaterials.2009.09.025  0.774
2009 Kloxin AM, Kasko AM, Salinas CN, Anseth KS. Photodegradable hydrogels for dynamic tuning of physical and chemical properties. Science (New York, N.Y.). 324: 59-63. PMID 19342581 DOI: 10.1126/Science.1169494  0.791
2008 Khire VS, Kloxin AM, Couch CL, Anseth KS, Bowman CN. Synthesis, Characterization and Cleavage of Linear Polymers Attached to Silica Nanoparticles Formed Using Thiol-acrylate Conjugate Addition Reactions. Journal of Polymer Science. Part a, Polymer Chemistry. 46: 6896-6906. PMID 20098666 DOI: 10.1002/Pola.22999  0.583
2008 Kloxin AM, Anseth KS. Materials science: Protein gels on the move. Nature. 454: 705-6. PMID 18685693 DOI: 10.1038/454705A  0.491
2008 Kloxin AM, Benton JA, Banaszek AL, Anseth KS. Controlled photolytic degradation of peg-based hydrogel surfaces to examine the effect of stiffness on valvular interstitial cells 8th World Biomaterials Congress 2008. 2: 593.  0.771
2008 Kloxin AM, Kasko AM, Anseth KS. Photoresponsive PEG-based 3D cell culture platforms American Chemical Society, Polymer Preprints, Division of Polymer Chemistry. 49: 268.  0.508
2006 Nuttelman CR, Kloxin AM, Anseth KS. Temporal changes in peg hydrogel structure influence human mesenchymal stem cell proliferation and matrix mineralization. Advances in Experimental Medicine and Biology. 585: 135-49. PMID 17120782 DOI: 10.1007/978-0-387-34133-0_10  0.73
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