Michael A. Chattergoon, Ph.D. - Publications

2003 University of Pennsylvania, Philadelphia, PA, United States 
DNA vaccine, HIV

42 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2014 Chattergoon MA, Latanich R, Quinn J, Winter ME, Buckheit RW, Blankson JN, Pardoll D, Cox AL. HIV and HCV activate the inflammasome in monocytes and macrophages via endosomal Toll-like receptors without induction of type 1 interferon. Plos Pathogens. 10: e1004082. PMID 24788318 DOI: 10.1371/journal.ppat.1004082  0.84
2014 Serti E, Werner JM, Chattergoon M, Cox AL, Lohmann V, Rehermann B. Monocytes activate natural killer cells via inflammasome-induced interleukin 18 in response to hepatitis C virus replication. Gastroenterology. 147: 209-220.e3. PMID 24685721 DOI: 10.1053/j.gastro.2014.03.046  0.84
2013 Osburn WO, Levine JS, Chattergoon MA, Thomas DL, Cox AL. Anti-inflammatory cytokines, pro-fibrogenic chemokines and persistence of acute HCV infection. Journal of Viral Hepatitis. 20: 404-13. PMID 23647957 DOI: 10.1111/jvh.12052  0.84
2011 Chattergoon MA, Levine JS, Latanich R, Osburn WO, Thomas DL, Cox AL. High plasma interleukin-18 levels mark the acute phase of hepatitis C virus infection. The Journal of Infectious Diseases. 204: 1730-40. PMID 21984735 DOI: 10.1093/infdis/jir642  0.84
2011 Muthumani K, Shedlock DJ, Choo DK, Fagone P, Kawalekar OU, Goodman J, Bian CB, Ramanathan AA, Atman P, Tebas P, Chattergoon MA, Choo AY, Weiner DB. HIV-mediated phosphatidylinositol 3-kinase/serine-threonine kinase activation in APCs leads to programmed death-1 ligand upregulation and suppression of HIV-specific CD8 T cells. Journal of Immunology (Baltimore, Md. : 1950). 187: 2932-43. PMID 21856939 DOI: 10.4049/jimmunol.1100594  0.84
2010 Kutzler MA, Kraynyak KA, Nagle SJ, Parkinson RM, Zharikova D, Chattergoon M, Maguire H, Muthumani K, Ugen K, Weiner DB. Plasmids encoding the mucosal chemokines CCL27 and CCL28 are effective adjuvants in eliciting antigen-specific immunity in vivo. Gene Therapy. 17: 72-82. PMID 19847203 DOI: 10.1038/gt.2009.112  0.84
2008 Chattergoon MA, Muthumani K, Tamura Y, Ramanathan M, Shames JP, Saulino V, Robinson TM, Montaner LJ, Weiner DB. DR5 activation of caspase-8 induces DC maturation and immune enhancement in vivo. Molecular Therapy : the Journal of the American Society of Gene Therapy. 16: 419-26. PMID 18087262 DOI: 10.1038/sj.mt.6300373  0.84
2006 Ramanathan MP, Chambers JA, Pankhong P, Chattergoon M, Attatippaholkun W, Dang K, Shah N, Weiner DB. Host cell killing by the West Nile Virus NS2B-NS3 proteolytic complex: NS3 alone is sufficient to recruit caspase-8-based apoptotic pathway. Virology. 345: 56-72. PMID 16243374 DOI: 10.1016/j.virol.2005.08.043  0.84
2005 Muthumani K, Choo AY, Hwang DS, Dayes NS, Chattergoon M, Mayilvahanan S, Thieu KP, Buckley PT, Emmanuel J, Premkumar A, Weiner DB. HIV-1 Viral protein-r (Vpr) protects against lethal superantigen challenge while maintaining homeostatic T cell levels in vivo. Molecular Therapy : the Journal of the American Society of Gene Therapy. 12: 910-21. PMID 16006193 DOI: 10.1016/j.ymthe.2005.05.009  0.84
2005 Kutzler MA, Robinson TM, Chattergoon MA, Choo DK, Choo AY, Choe PY, Ramanathan MP, Parkinson R, Kudchodkar S, Tamura Y, Sidhu M, Roopchand V, Kim JJ, Pavlakis GN, Felber BK, et al. Coimmunization with an optimized IL-15 plasmid results in enhanced function and longevity of CD8 T cells that are partially independent of CD4 T cell help. Journal of Immunology (Baltimore, Md. : 1950). 175: 112-23. PMID 15972637  0.84
2004 Chattergoon MA, Saulino V, Shames JP, Stein J, Montaner LJ, Weiner DB. Co-immunization with plasmid IL-12 generates a strong T-cell memory response in mice. Vaccine. 22: 1744-50. PMID 15068858 DOI: 10.1016/j.vaccine.2004.01.036  0.84
2003 Agadjanyan MG, Chattergoon MA, Holterman MJ, Monzavi-Karbassi B, Kim JJ, Dentchev T, Wilson D, Ayyavoo V, Montaner LJ, Kieber-Emmons T, Sekaly RP, Weiner DB. Costimulatory molecule immune enhancement in a plasmid vaccine model is regulated in part through the Ig constant-like domain of CD80/86. Journal of Immunology (Baltimore, Md. : 1950). 171: 4311-9. PMID 14530356  0.84
2003 Chattergoon MA, Shames JP, Weiner DB. Engineering cross-presentation in vivo. Expert Opinion On Biological Therapy. 3: 887-94. PMID 12943447 DOI: 10.1517/14712598.3.6.887  0.84
2003 Muthumani K, Choo AY, Hwang DS, Chattergoon MA, Dayes NN, Zhang D, Lee MD, Duvvuri U, Weiner DB. Mechanism of HIV-1 viral protein R-induced apoptosis. Biochemical and Biophysical Research Communications. 304: 583-92. PMID 12729593 DOI: 10.1016/S0006-291X(03)00631-4  0.84
2003 Boyer JD, Kutzler MA, Chattergoon MA, Calarota SA, Pavlakis G, Sekaly RP, MacGregor RR, Weiner DB. Engineering DNA vaccination as an approach to HIV immune therapy Clinical and Applied Immunology Reviews. 3: 183-197. DOI: 10.1016/S1529-1049(02)00158-7  0.84
2002 Boyer JD, Chattergoon M, Muthumani K, Kudchodkar S, Kim J, Bagarazzi M, Pavlakis G, Sekaly R, Weiner DB. Next generation DNA vaccines for HIV-1. Journal of Liposome Research. 12: 137-42. PMID 12604047 DOI: 10.1081/LPR-120004786  0.84
2002 Baumeister MA, Chattergoon MA, Weiner DB. Prospects for an HIV vaccine: conventional approaches and DNA immunization. Biotechnology & Genetic Engineering Reviews. 19: 205-42. PMID 12520879  0.84
2002 Kragol G, Hoffmann R, Chattergoon MA, Lovas S, Cudic M, Bulet P, Condie BA, Rosengren KJ, Montaner LJ, Otvos L. Identification of crucial residues for the antibacterial activity of the proline-rich peptide, pyrrhocoricin. European Journal of Biochemistry / Febs. 269: 4226-37. PMID 12199701 DOI: 10.1046/j.1432-1033.2002.03119.x  0.84
2002 Muthumani K, Zhang D, Hwang DS, Kudchodkar S, Dayes NS, Desai BM, Malik AS, Yang JS, Chattergoon MA, Maguire HC, Weiner DB. Adenovirus encoding HIV-1 Vpr activates caspase 9 and induces apoptotic cell death in both p53 positive and negative human tumor cell lines. Oncogene. 21: 4613-25. PMID 12096338 DOI: 10.1038/sj.onc.1205549  0.84
2002 Chattergoon MA, Maguire HH, Robinson TM, Serrano E, Boyer JD, Weiner DB. Plasmid immunization primes unique DTH responses to HIV-1MN envelope epitopes as compared to recombinant protein vaccination. Hybridoma and Hybridomics. 21: 117-22. PMID 12031101 DOI: 10.1089/153685902317401717  0.84
2002 Chattergoon M, Weiner D. Plasmid DNA: Is there a toll on the way to apoptosis? Journal of Gene Medicine. 4: 25-26. PMID 11828384 DOI: 10.1002/jgm.238  0.84
2001 Boyer J, Im-Sin J, Kimusa J, Chattergoon M, Chalian A, McCallus D, Conway D, Ugen K, Ginsberg R, Patcuk C, Satishchandran C, Boyer JD, Weiner DB. Engineering a DNA vaccine for HIV-1 Japanese Journal of Chemotherapy. 49: 112.  0.84
2000 Sin JI, Kim J, Chattergoon M, Ayyavoo V, McCallus D, Ugen KE, Boyer JD, Weiner DB. Engineering of DNA vaccines using molecular adjuvant plasmids. Developments in Biologicals. 104: 187-98. PMID 11713819  0.84
2000 Chattergoon MA, Kim JJ, Yang JS, Robinson TM, Lee DJ, Dentchev T, Wilson DM, Ayyavoo V, Weiner DB. Targeted antigen delivery to antigen-presenting cells including dendritic cells by engineered Fas-mediated apoptosis. Nature Biotechnology. 18: 974-9. PMID 10973219 DOI: 10.1038/79470  0.84
1999 Bagarazzi ML, Boyer JD, Javadian MA, Chattergoon MA, Shah AR, Cohen AD, Bennett MK, Ciccarelli RB, Ugen KE, Weiner DB. Systemic and mucosal immunity is elicited after both intramuscular and intravaginal delivery of human immunodeficiency virus type 1 DNA plasmid vaccines to pregnant chimpanzees. The Journal of Infectious Diseases. 180: 1351-5. PMID 10479171 DOI: 10.1086/314978  0.84
1999 Boyer JD, Chattergoon MA, Ugen KE, Shah A, Bennett M, Cohen A, Nyland S, Lacy KE, Bagarazzi ML, Higgins TJ, Baine Y, Ciccarelli RB, Ginsberg RS, MacGregor RR, Weiner DB. Enhancement of cellular immune response in HIV-1 seropositive individuals: A DNA-based trial. Clinical Immunology (Orlando, Fla.). 90: 100-7. PMID 9884357 DOI: 10.1006/clim.1998.4616  0.84
1998 Kim JJ, Trivedi NN, Wilson DM, Mahalingam S, Morrison L, Tsai A, Chattergoon MA, Dang K, Patel M, Ahn L, Boyer JD, Chalian AA, Schoemaker H, Kieber-Emmons T, Agadjanyan MA, et al. Molecular and immunological analysis of genetic prostate specific antigen (PSA) vaccine. Oncogene. 17: 3125-35. PMID 9872328 DOI: 10.1038/sj.onc.1201736  0.84
1998 Boyer JD, Chattergoon M, Shah A, Ginsberg R, MacGregor RR, Weiner DB. HIV-1 DNA based vaccine induces a CD8 mediated cross-clade CTL response. Developments in Biological Standardization. 95: 147-53. PMID 9855425  0.84
1998 Bagarazzi ML, Boyer JD, Ugen KE, Javadian MA, Chattergoon M, Shah A, Bennett M, Ciccarelli R, Carrano R, Coney L, Weiner DB. Safety and immunogenicity of HIV-1 DNA constructs in chimpanzees. Vaccine. 16: 1836-41. PMID 9795389 DOI: 10.1016/S0264-410X(98)00178-9  0.84
1998 Ugen KE, Nyland SB, Boyer JD, Vidal C, Lera L, Rasheid S, Chattergoon M, Bagarazzi ML, Ciccarelli R, Higgins T, Baine Y, Ginsberg R, Macgregor RR, Weiner DB. DNA vaccination with HIV-1 expressing constructs elicits immune responses in humans. Vaccine. 16: 1818-21. PMID 9795386 DOI: 10.1016/S0264-410X(98)00180-7  0.84
1998 MacGregor RR, Boyer JD, Ugen KE, Lacy KE, Gluckman SJ, Bagarazzi ML, Chattergoon MA, Baine Y, Higgins TJ, Ciccarelli RB, Coney LR, Ginsberg RS, Weiner DB. First human trial of a DNA-based vaccine for treatment of human immunodeficiency virus type 1 infection: safety and host response. The Journal of Infectious Diseases. 178: 92-100. PMID 9652427  0.84
1998 Chattergoon MA, Robinson TM, Boyer JD, Weiner DB. Specific immune induction following DNA-based immunization through in vivo transfection and activation of macrophages/antigen-presenting cells. Journal of Immunology (Baltimore, Md. : 1950). 160: 5707-18. PMID 9637479  0.84
1998 Boyer J, Ugen K, Wang B, Chattergoon M, Tsai A, Merva M, Weiner DB. Induction of a TH1 type cellular immune response to the human immunodeficiency type 1 virus by in vivo DNA inoculation. Developments in Biological Standardization. 92: 169-74. PMID 9554272  0.84
1998 Kim JJ, Trivedi NN, Nottingham LK, Morrison L, Tsai A, Hu Y, Mahalingam S, Dang K, Ahn L, Doyle NK, Wilson DM, Chattergoon MA, Chalian AA, Boyer JD, Agadjanyan MG, et al. Modulation of amplitude and direction of in vivo immune responses by co-administration of cytokine gene expression cassettes with DNA immunogens. European Journal of Immunology. 28: 1089-103. PMID 9541605 DOI: 10.1002/(SICI)1521-4141(199803)28:03<1089::AID-IMMU1089>3.0.CO;2-L  0.84
1998 Agadjanyan MG, Chattergoon MA, Petrushina I, Bennett M, Kim J, Ugen KE, Kieber-Emmons T, Weiner DB. Monoclonal antibodies define a cellular antigen involved in HTLV-I infection. Hybridoma. 17: 9-19. PMID 9523233  0.84
1997 Boyer JD, Ugen KE, Chattergoon M, Wang B, Shah A, Agadjanyan M, Bagarazzi ML, Javadian A, Carrano R, Coney L, Williams WV, Weiner DB. DNA vaccination as anti-human immunodeficiency virus immunotherapy in infected chimpanzees. The Journal of Infectious Diseases. 176: 1501-9. PMID 9395361  0.84
1997 Chattergoon M, Boyer J, Weiner DB. Genetic immunization: a new era in vaccines and immune therapeutics. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 11: 753-63. PMID 9271360  0.84
1997 Bagarazzi ML, Boyer JD, Javadian MA, Chattergoon M, Dang K, Kim G, Shah J, Wang B, Weiner DB. Safety and immunogenicity of intramuscular and intravaginal delivery of HIV-1 DNA constructs to infant chimpanzees. Journal of Medical Primatology. 26: 27-33. PMID 9271186  0.84
1997 Kim JJ, Ayyavoo V, Bagarazzi ML, Chattergoon M, Boyer JD, Wang B, Weiner DB. Development of a multicomponent candidate vaccine for HIV-1. Vaccine. 15: 879-83. PMID 9234538 DOI: 10.1016/S0264-410X(96)00260-5  0.84
1997 Kim JJ, Bagarazzi ML, Trivedi N, Hu Y, Kazahaya K, Wilson DM, Ciccarelli R, Chattergoon MA, Dang K, Mahalingam S, Chalian AA, Agadjanyan MG, Boyer JD, Wang B, Weiner DB. Engineering of in vivo immune responses to DNA immunization via codelivery of costimulatory molecule genes. Nature Biotechnology. 15: 641-6. PMID 9219266 DOI: 10.1038/nbt0797-641  0.84
1997 Boyer JD, Ugen KE, Wang B, Agadjanyan M, Gilbert L, Bagarazzi ML, Chattergoon M, Frost P, Javadian A, Williams WV, Refaeli Y, Ciccarelli RB, McCallus D, Coney L, Weiner DB. Protection of chimpanzees from high-dose heterologous HIV-1 challenge by DNA vaccination. Nature Medicine. 3: 526-32. PMID 9142121  0.84
1997 Kim JJ, Ayyavoo V, Bagarazzi ML, Chattergoon MA, Dang K, Wang B, Boyer JD, Weiner DB. In vivo engineering of a cellular immune response by coadministration of IL-12 expression vector with a DNA immunogen. Journal of Immunology (Baltimore, Md. : 1950). 158: 816-26. PMID 8992999  0.84
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