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Dominick J. Laddy, Ph.D. - Publications

Affiliations: 
2008 University of Pennsylvania, Philadelphia, PA, United States 
Area:
DNA vaccine, HIV
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28/29 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2022 Nemes E, Fiore-Gartland A, Boggiano C, Coccia M, D'Souza P, Gilbert P, Ginsberg A, Hyrien O, Laddy D, Makar K, McElrath MJ, Ramachandra L, Schmidt AC, Shororbani S, Sunshine J, et al. The quest for vaccine-induced immune correlates of protection against tuberculosis. Vaccine Insights. 1: 165-181. PMID 37091190 DOI: 10.18609/vac/2022.027  0.419
2021 White AD, Sibley L, Sarfas C, Morrison A, Gullick J, Clark S, Gleeson F, McIntyre A, Arlehamn CL, Sette A, Salguero FJ, Rayner E, Rodriguez E, Puentes E, Laddy D, et al. MTBVAC vaccination protects rhesus macaques against aerosol challenge with M. tuberculosis and induces immune signatures analogous to those observed in clinical studies. Npj Vaccines. 6: 4. PMID 33397991 DOI: 10.1038/s41541-020-00262-8  0.448
2020 Vierboom MPM, Chenine AL, Darrah PA, Vervenne RAW, Boot C, Hofman SO, Sombroek CC, Dijkman K, Khayum MA, Stammes MA, Haanstra KG, Hoffmann C, Schmitt D, Silvestre N, White AG, ... ... Laddy DJ, et al. Evaluation of heterologous prime-boost vaccination strategies using chimpanzee adenovirus and modified vaccinia virus for TB subunit vaccination in rhesus macaques. Npj Vaccines. 5: 39. PMID 33580052 DOI: 10.1038/s41541-020-0189-2  0.493
2020 Roordink D, Williams A, Fritzell B, Laddy DJ, Gerdil E, Graffin AM, Tait D, van der Pol L, van den Brink I, Holleman M, Thole J, Voss G, Lempicki M, Thiry G. The TB vaccine development pathway - An innovative approach to accelerating global TB vaccine development. Tuberculosis (Edinburgh, Scotland). 126: 102040. PMID 33310626 DOI: 10.1016/j.tube.2020.102040  0.416
2020 Vierboom MPM, Chenine AL, Darrah PA, Vervenne RAW, Boot C, Hofman SO, Sombroek CC, Dijkman K, Khayum MA, Stammes MA, Haanstra KG, Hoffmann C, Schmitt D, Silvestre N, White AG, ... ... Laddy DJ, et al. Evaluation of heterologous prime-boost vaccination strategies using chimpanzee adenovirus and modified vaccinia virus for TB subunit vaccination in rhesus macaques. Npj Vaccines. 5: 39. PMID 32435513 DOI: 10.1038/s41541-020-0189-2  0.499
2020 Darrah PA, Zeppa JJ, Maiello P, Hackney JA, Wadsworth MH, Hughes TK, Pokkali S, Swanson PA, Grant NL, Rodgers MA, Kamath M, Causgrove CM, Laddy DJ, Bonavia A, Casimiro D, et al. Prevention of tuberculosis in macaques after intravenous BCG immunization. Nature. 577: 95-102. PMID 31894150 DOI: 10.1038/S41586-019-1817-8  0.562
2019 Darrah PA, DiFazio RM, Maiello P, Gideon HP, Myers AJ, Rodgers MA, Hackney JA, Lindenstrom T, Evans T, Scanga CA, Prikhodko V, Andersen P, Lin PL, Laddy D, Roederer M, et al. Boosting BCG with proteins or rAd5 does not enhance protection against tuberculosis in rhesus macaques. Npj Vaccines. 4: 21. PMID 31149352 DOI: 10.1038/s41541-019-0113-9  0.454
2019 Fitzpatrick M, Ho MM, Clark S, Dagg B, Khatri B, Lanni F, Williams A, Brennan M, Laddy D, Walker B. Comparison of pellicle and shake flask-grown BCG strains by quality control assays and protection studies. Tuberculosis (Edinburgh, Scotland). 114: 47-53. PMID 30711157 DOI: 10.1016/J.Tube.2018.10.013  0.458
2018 Hansen SG, Zak DE, Xu G, Ford JC, Marshall EE, Malouli D, Gilbride RM, Hughes CM, Ventura AB, Ainslie E, Randall KT, Selseth AN, Rundstrom P, Herlache L, Lewis MS, ... ... Laddy DJ, et al. Prevention of tuberculosis in rhesus macaques by a cytomegalovirus-based vaccine. Nature Medicine. PMID 29334373 DOI: 10.1038/Nm.4473  0.545
2017 Laddy DJ, Bonavia A, Hanekom WA, Kaushal D, Williams A, Roederer M, Seder RA, Sharpe S, Verreck FAW, Darrah PA. Toward Tuberculosis Vaccine Development: Recommendations for NHP Study Design. Infection and Immunity. PMID 29203540 DOI: 10.1128/Iai.00776-17  0.481
2016 Lahey T, Laddy D, Hill K, Schaeffer J, Hogg A, Keeble J, Dagg B, Ho MM, Arbeit RD, von Reyn CF. Immunogenicity and Protective Efficacy of the DAR-901 Booster Vaccine in a Murine Model of Tuberculosis. Plos One. 11: e0168521. PMID 27997597 DOI: 10.1371/Journal.Pone.0168521  0.544
2016 Smith CM, Proulx MK, Olive AJ, Laddy D, Mishra BB, Moss C, Gutierrez NM, Bellerose MM, Barreira-Silva P, Phuah JY, Baker RE, Behar SM, Kornfeld H, Evans TG, Beamer G, et al. Tuberculosis Susceptibility and Vaccine Protection Are Independently Controlled by Host Genotype. Mbio. 7. PMID 27651361 DOI: 10.1128/Mbio.01516-16  0.496
2016 Sharpe S, White A, Gleeson F, McIntyre A, Smyth D, Clark S, Sarfas C, Laddy D, Rayner E, Hall G, Williams A, Dennis M. Ultra low dose aerosol challenge with Mycobacterium tuberculosis leads to divergent outcomes in rhesus and cynomolgus macaques. Tuberculosis (Edinburgh, Scotland). 96: 1-12. PMID 26786648 DOI: 10.1016/J.Tube.2015.10.004  0.412
2014 Villarreal DO, Walters J, Laddy DJ, Yan J, Weiner DB. Multivalent TB vaccines targeting the esx gene family generate potent and broad cell-mediated immune responses superior to BCG. Human Vaccines & Immunotherapeutics. 10: 2188-98. PMID 25424922 DOI: 10.4161/Hv.29574  0.662
2013 Velmurugan K, Grode L, Chang R, Fitzpatrick M, Laddy D, Hokey D, Derrick S, Morris S, McCown D, Kidd R, Gengenbacher M, Eisele B, Kaufmann SH, Fulkerson J, Brennan MJ. Nonclinical Development of BCG Replacement Vaccine Candidates. Vaccines. 1: 120-38. PMID 26343962 DOI: 10.3390/Vaccines1020120  0.519
2011 Pillet S, Kobasa D, Meunier I, Gray M, Laddy D, Weiner DB, von Messling V, Kobinger GP. Cellular immune response in the presence of protective antibody levels correlates with protection against 1918 influenza in ferrets. Vaccine. 29: 6793-801. PMID 21211587 DOI: 10.1016/J.Vaccine.2010.12.059  0.675
2009 Muthumani G, Laddy DJ, Sundaram SG, Fagone P, Shedlock DJ, Kannan S, Wu L, Chung CW, Lankaraman KM, Burns J, Muthumani K, Weiner DB. Co-immunization with an optimized plasmid-encoded immune stimulatory interleukin, high-mobility group box 1 protein, results in enhanced interferon-gamma secretion by antigen-specific CD8 T cells. Immunology. 128: e612-20. PMID 19740322 DOI: 10.1111/J.1365-2567.2009.03044.X  0.674
2009 Yin J, Dai A, Laddy DJ, Yan J, Arango T, Khan AS, Lewis MG, Andersen H, Kutzler MA, Draghia-Akli R, Weiner DB, Boyer JD. High dose of plasmid IL-15 inhibits immune responses in an influenza non-human primates immunogenicity model. Virology. 393: 49-55. PMID 19683780 DOI: 10.1016/J.Virol.2009.07.017  0.578
2009 Kraynyak KA, Kutzler MA, Cisper NJ, Laddy DJ, Morrow MP, Waldmann TA, Weiner DB. Plasmid-encoded interleukin-15 receptor alpha enhances specific immune responses induced by a DNA vaccine in vivo. Human Gene Therapy. 20: 1143-56. PMID 19530914 DOI: 10.1089/Hum.2009.025  0.682
2009 Morrow MP, Pankhong P, Laddy DJ, Schoenly KA, Yan J, Cisper N, Weiner DB. Comparative ability of IL-12 and IL-28B to regulate Treg populations and enhance adaptive cellular immunity. Blood. 113: 5868-77. PMID 19304955 DOI: 10.1182/Blood-2008-11-190520  0.601
2009 Laddy DJ, Yan J, Khan AS, Andersen H, Cohn A, Greenhouse J, Lewis M, Manischewitz J, King LR, Golding H, Draghia-Akli R, Weiner DB. Electroporation of synthetic DNA antigens offers protection in nonhuman primates challenged with highly pathogenic avian influenza virus. Journal of Virology. 83: 4624-30. PMID 19211745 DOI: 10.1128/Jvi.02335-08  0.659
2008 Muthumani K, Choo AY, Shedlock DJ, Laddy DJ, Sundaram SG, Hirao L, Wu L, Thieu KP, Chung CW, Lankaraman KM, Tebas P, Silvestri G, Weiner DB. Human immunodeficiency virus type 1 Nef induces programmed death 1 expression through a p38 mitogen-activated protein kinase-dependent mechanism. Journal of Virology. 82: 11536-44. PMID 18799583 DOI: 10.1128/Jvi.00485-08  0.62
2008 Laddy DJ, Yan J, Kutzler M, Kobasa D, Kobinger GP, Khan AS, Greenhouse J, Sardesai NY, Draghia-Akli R, Weiner DB. Heterosubtypic protection against pathogenic human and avian influenza viruses via in vivo electroporation of synthetic consensus DNA antigens. Plos One. 3: e2517. PMID 18575608 DOI: 10.1371/Journal.Pone.0002517  0.646
2008 Muthumani K, Lankaraman KM, Laddy DJ, Sundaram SG, Chung CW, Sako E, Wu L, Khan A, Sardesai N, Kim JJ, Vijayachari P, Weiner DB. Immunogenicity of novel consensus-based DNA vaccines against Chikungunya virus. Vaccine. 26: 5128-34. PMID 18471943 DOI: 10.1016/j.vaccine.2008.03.060  0.647
2007 Laddy DJ, Yan J, Corbitt N, Kobasa D, Kobinger GP, Weiner DB. Immunogenicity of novel consensus-based DNA vaccines against avian influenza. Vaccine. 25: 2984-9. PMID 17306909 DOI: 10.1016/J.Vaccine.2007.01.063  0.627
2006 Laddy DJ, Weiner DB. From plasmids to protection: a review of DNA vaccines against infectious diseases. International Reviews of Immunology. 25: 99-123. PMID 16818367 DOI: 10.1080/08830180600785827  0.647
2004 Muthumani K, Desai BM, Hwang DS, Choo AY, Laddy DJ, Thieu KP, Rao RG, Weiner DB. HIV-1 Vpr and anti-inflammatory activity. Dna and Cell Biology. 23: 239-47. PMID 15142381 DOI: 10.1089/104454904773819824  0.516
2004 Otero M, Calarota SA, Felber B, Laddy D, Pavlakis G, Boyer JD, Weiner DB. Resiquimod is a modest adjuvant for HIV-1 gag-based genetic immunization in a mouse model. Vaccine. 22: 1782-90. PMID 15068862 DOI: 10.1016/J.Vaccine.2004.01.037  0.643
Low-probability matches (unlikely to be authored by this person)
2014 Johnson DH, Via LE, Kim P, Laddy D, Lau CY, Weinstein EA, Jain S. Nuclear imaging: a powerful novel approach for tuberculosis. Nuclear Medicine and Biology. 41: 777-84. PMID 25195017 DOI: 10.1016/J.Nucmedbio.2014.08.005  0.26
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