| Year |
Citation |
Score |
| 2020 |
Hansen J, Baum A, Pascal KE, Russo V, Giordano S, Wloga E, Fulton BO, Yan Y, Koon K, Patel K, Chung KM, Hermann A, Ullman E, Cruz J, Rafique A, ... ... Franklin M, et al. Studies in humanized mice and convalescent humans yield a SARS-CoV-2 antibody cocktail. Science (New York, N.Y.). PMID 32540901 DOI: 10.1126/Science.Abd0827 |
0.338 |
|
| 2020 |
Atanasio A, Franklin M, Ben L, Badithe A, Bautista J, Kamat V, Hernandez AR, Olson W, Murphy A, sleeman m, Orengo J. Targeting birch allergy with monoclonal IgG antibodies that bind allergen and prevent IgE effector cell activation Journal of Allergy and Clinical Immunology. 145: AB62. DOI: 10.1016/J.Jaci.2019.12.719 |
0.314 |
|
| 2019 |
Macdonald LE, Meagher KA, Franklin MC, Levenkova N, Hansen J, Badithe AT, Zhong M, Krueger P, Rafique A, Tu N, Shevchuk J, Wadhwa S, Ehrlich G, Bautista J, Grant C, et al. Kappa-on-Heavy (KoH) bodies are a distinct class of fully-human antibody-like therapeutic agents with antigen-binding properties. Proceedings of the National Academy of Sciences of the United States of America. PMID 31879340 DOI: 10.1073/pnas.1901734117 |
0.378 |
|
| 2018 |
Orengo JM, Radin AR, Kamat V, Badithe A, Ben LH, Bennett BL, Zhong S, Birchard D, Limnander A, Rafique A, Bautista J, Kostic A, Newell D, Duan X, Franklin MC, et al. Treating cat allergy with monoclonal IgG antibodies that bind allergen and prevent IgE engagement. Nature Communications. 9: 1421. PMID 29650949 DOI: 10.1038/S41467-018-03636-8 |
0.314 |
|
| 2016 |
Franklin MC, Rudolph MJ, Ginter C, Cassidy MS, Cheung J. Structures of paraoxon-inhibited human acetylcholinesterase reveal perturbations of the acyl loop and the dimer interface. Proteins. PMID 27191504 DOI: 10.1002/Prot.25073 |
0.33 |
|
| 2015 |
Franklin MC, Cheung J, Rudolph MJ, Burshteyn F, Cassidy M, Gary E, Hillerich B, Yao ZK, Carlier PR, Totrov M, Love JD. Structural Genomics for Drug Design against the Pathogen Coxiella burnetii. Proteins. PMID 26033498 DOI: 10.1002/Prot.24841 |
0.376 |
|
| 2015 |
Dutta K, Varshney AK, Franklin MC, Goger M, Wang X, Fries BC. Mechanisms mediating enhanced neutralization efficacy of staphylococcal enterotoxin B by combinations of monoclonal antibodies. The Journal of Biological Chemistry. 290: 6715-30. PMID 25572397 DOI: 10.1074/Jbc.M114.630715 |
0.363 |
|
| 2014 |
Rudolph MJ, Vance DJ, Cheung J, Franklin MC, Burshteyn F, Cassidy MS, Gary EN, Herrera C, Shoemaker CB, Mantis NJ. Crystal structures of ricin toxin's enzymatic subunit (RTA) in complex with neutralizing and non-neutralizing single-chain antibodies. Journal of Molecular Biology. 426: 3057-68. PMID 24907552 DOI: 10.1016/J.Jmb.2014.05.026 |
0.414 |
|
| 2012 |
Flygare JA, Beresini M, Budha N, Chan H, Chan IT, Cheeti S, Cohen F, Deshayes K, Doerner K, Eckhardt SG, Elliott LO, Feng B, Franklin MC, Reisner SF, Gazzard L, et al. Discovery of a potent small-molecule antagonist of inhibitor of apoptosis (IAP) proteins and clinical candidate for the treatment of cancer (GDC-0152). Journal of Medicinal Chemistry. 55: 4101-13. PMID 22413863 DOI: 10.1021/Jm300060K |
0.316 |
|
| 2011 |
Franklin MC, Navarro EC, Wang Y, Patel S, Singh P, Zhang Y, Persaud K, Bari A, Griffith H, Shen L, Balderes P, Kussie P. The structural basis for the function of two anti-VEGF receptor 2 antibodies. Structure (London, England : 1993). 19: 1097-107. PMID 21827946 DOI: 10.1016/J.Str.2011.01.019 |
0.372 |
|
| 2009 |
Cohen F, Alicke B, Elliott LO, Flygare JA, Goncharov T, Keteltas SF, Franklin MC, Frankovitz S, Stephan JP, Tsui V, Vucic D, Wong H, Fairbrother WJ. Orally bioavailable antagonists of inhibitor of apoptosis proteins based on an azabicyclooctane scaffold. Journal of Medicinal Chemistry. 52: 1723-30. PMID 19228017 DOI: 10.1021/Jm801450C |
0.331 |
|
| 2006 |
Zobel K, Wang L, Varfolomeev E, Franklin MC, Elliott LO, Wallweber HJ, Okawa DC, Flygare JA, Vucic D, Fairbrother WJ, Deshayes K. Design, synthesis, and biological activity of a potent Smac mimetic that sensitizes cancer cells to apoptosis by antagonizing IAPs. Acs Chemical Biology. 1: 525-33. PMID 17168540 DOI: 10.1021/Cb600276Q |
0.405 |
|
| 2005 |
Vucic D, Franklin MC, Wallweber HJ, Das K, Eckelman BP, Shin H, Elliott LO, Kadkhodayan S, Deshayes K, Salvesen GS, Fairbrother WJ. Engineering ML-IAP to produce an extraordinarily potent caspase 9 inhibitor: implications for Smac-dependent anti-apoptotic activity of ML-IAP. The Biochemical Journal. 385: 11-20. PMID 15485396 DOI: 10.1042/Bj20041108 |
0.352 |
|
| 2004 |
Franklin MC, Carey KD, Vajdos FF, Leahy DJ, de Vos AM, Sliwkowski MX. Insights into ErbB signaling from the structure of the ErbB2-pertuzumab complex. Cancer Cell. 5: 317-28. PMID 15093539 DOI: 10.1016/S1535-6108(04)00083-2 |
0.396 |
|
| 2002 |
Yang G, Franklin M, Li J, Lin TC, Konigsberg W. Correlation of the kinetics of finger domain mutants in RB69 DNA polymerase with its structure Biochemistry. 41: 2526-2534. PMID 11851399 DOI: 10.1021/Bi0119924 |
0.35 |
|
| 2001 |
Wang J, Song JJ, Seong IS, Franklin MC, Kamtekar S, Eom SH, Chung CH. Nucleotide-dependent conformational changes in a protease-associated ATPase HsIU. Structure (London, England : 1993). 9: 1107-16. PMID 11709174 DOI: 10.1016/S0969-2126(01)00670-0 |
0.541 |
|
| 2001 |
Franklin MC, Wang J, Steitz TA. Structure of the replicating complex of a pol alpha family DNA polymerase. Cell. 105: 657-67. PMID 11389835 DOI: 10.1016/S0092-8674(01)00367-1 |
0.469 |
|
| 2001 |
Wang J, Song JJ, Franklin MC, Kamtekar S, Im YJ, Rho SH, Seong IS, Lee CS, Chung CH, Eom SH. Crystal structures of the HslVU peptidase-ATPase complex reveal an ATP-dependent proteolysis mechanism. Structure (London, England : 1993). 9: 177-84. PMID 11250202 DOI: 10.1016/S0969-2126(01)00570-6 |
0.544 |
|
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