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Weikai Li, Ph.D. - Publications

Affiliations: 
2004 Yale University, New Haven, CT 
Area:
Biochemistry, structural chemistry
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32 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2022 Liu S, Shen G, Li W. Structural and cellular basis of vitamin K antagonism. Journal of Thrombosis and Haemostasis : Jth. PMID 35748323 DOI: 10.1111/jth.15800  0.311
2022 Shen G, Li C, Cao Q, Megta AK, Li S, Gao M, Liu H, Shen Y, Chen Y, Yu H, Li S, Li W. Structural features determining the vitamin K epoxide reduction activity in the VKOR family of membrane oxidoreductases. The Febs Journal. PMID 35113495 DOI: 10.1111/febs.16386  0.329
2021 Cheng M, Guo C, Li W, Gross ML. Free-Radical Membrane Protein Footprinting by Photolysis of Perfluoroisopropyl Iodide Partitioned to Detergent Micelle by Sonication. Angewandte Chemie (International Ed. in English). PMID 33751812 DOI: 10.1002/anie.202014096  0.414
2020 Liu S, Li S, Shen G, Sukumar N, Krezel AM, Li W. Structural basis of antagonizing the vitamin K catalytic cycle for anticoagulation. Science (New York, N.Y.). PMID 33154105 DOI: 10.1126/science.abc5667  0.31
2020 Li S, Liu S, Yang Y, Li W. Characterization of Warfarin Inhibition Kinetics Requires Stabilization of Intramembrane Vitamin K Epoxide Reductases. Journal of Molecular Biology. PMID 32445640 DOI: 10.1016/J.Jmb.2020.05.009  0.637
2020 Li S, Liu S, Liu XR, Zhang MM, Li W. Competitive tight-binding inhibition of VKORC1 underlies warfarin dosage variation and antidotal efficacy. Blood Advances. 4: 2202-2212. PMID 32433747 DOI: 10.1182/Bloodadvances.2020001750  0.463
2019 Greenberg ZJ, Monlish DA, Bartnett RL, Yang Y, Shen G, Li W, Bednarski JJ, Schuettpelz LG. The Tetraspanin CD53 Regulates Early B Cell Development by Promoting IL-7R Signaling. Journal of Immunology (Baltimore, Md. : 1950). PMID 31748347 DOI: 10.1182/Blood-2019-131641  0.377
2019 Li W, Liu S, Li S. Structural Basis of Vitamin K Antagonism Blood. 134: 482-482. DOI: 10.1182/Blood-2019-127324  0.345
2018 Sukumar N, Liu S, Li W, Mathews FS, Mitra B, Kandavelu P. Structure of the monotopic membrane protein (S)-mandelate dehydrogenase at 2.2Å resolution. Biochimie. PMID 30071260 DOI: 10.1016/J.Biochi.2018.07.017  0.641
2018 Shen G, Li S, Cui W, Liu S, Liu Q, Yang Y, Gross M, Li W. Stabilization of warfarin-binding pocket of VKORC1 and VKORL1 by a peripheral region determines their different sensitivity to warfarin inhibition. Journal of Thrombosis and Haemostasis : Jth. PMID 29665197 DOI: 10.1111/Jth.14127  0.561
2017 Shen G, Li S, Cui W, Liu S, Yang Y, Gross M, Li W. Membrane Protein Structure in Live Cells: Methodology for Studying Drug Interaction by Mass Spectrometry-Based Footprinting. Biochemistry. PMID 29192498 DOI: 10.1021/Acs.Biochem.7B00874  0.514
2017 Li S, Shen GM, Li W. Intramembrane thiol oxidoreductases: evolutionary convergence and structural controversy. Biochemistry. PMID 29064673 DOI: 10.1021/Acs.Biochem.7B00876  0.522
2017 Takahashi T, Hsiao HM, Tanaka S, Li W, Higashikubo R, Scozzi D, Bharat A, Ritter JH, Krupnick AS, Gelman AE, Kreisel D. PD-1 expression on CD8(+) T cells regulates their differentiation within lung allografts and is critical for tolerance induction. American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons. PMID 28730633 DOI: 10.1111/Ajt.14437  0.303
2017 Yang Y, Ke N, Liu S, Li W. Methods for Structural and Functional Analyses of Intramembrane Prenyltransferases in the UbiA Superfamily. Methods in Enzymology. 584: 309-347. PMID 28065269 DOI: 10.1016/Bs.Mie.2016.10.032  0.594
2016 Shen G, Cui W, Zhang H, Zhou F, Huang W, Liu Q, Yang Y, Li S, Bowman GR, Sadler JE, Gross ML, Li W. Warfarin traps human vitamin K epoxide reductase in an intermediate state during electron transfer. Nature Structural & Molecular Biology. PMID 27918545 DOI: 10.1038/Nsmb.3333  0.671
2016 Liu Y, Li W, Luehmann HP, Zhao Y, Detering L, Sultan DE, Hsiao HM, Krupnick AS, Gelman AE, Combadiere C, Gropler RJ, Brody SL, Kreisel D. Noninvasive Imaging of CCR2(+) Cells in Ischemia Reperfusion Injury after Lung Transplantation. American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons. PMID 27273836 DOI: 10.1111/Ajt.13907  0.306
2016 Li W. Bringing Bioactive Compounds into Membranes: The UbiA Superfamily of Intramembrane Aromatic Prenyltransferases. Trends in Biochemical Sciences. PMID 26922674 DOI: 10.1016/J.Tibs.2016.01.007  0.591
2015 Hsao HM, Li W, Gelman AE, Krupnick AS, Kreisel D. The Role of Lymphoid Neogenesis in Allografts. American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons. PMID 26614734 DOI: 10.1111/Ajt.13645  0.639
2014 Huo T, Zhang Y, Li W, Yang H, Jiang H, Sun G. Effect of realgar on extracellular amino acid neurotransmitters in hippocampal CA1 region determined by online microdialysis–dansyl chloride derivatization–high-performance liquid chromatography and fluorescence detection. Biomedical Chromatography : Bmc. 28: 1254-62. PMID 25237708 DOI: 10.1002/bmc.3154  0.407
2014 Cheng W, Li W. Structural insights into ubiquinone biosynthesis in membranes. Science (New York, N.Y.). 343: 878-81. PMID 24558159 DOI: 10.1126/Science.1246774  0.418
2014 Liu S, Cheng W, Fowle Grider R, Shen G, Li W. Structures of an intramembrane vitamin K epoxide reductase homolog reveal control mechanisms for electron transfer. Nature Communications. 5: 3110. PMID 24477003 DOI: 10.1038/Ncomms4110  0.603
2014 Park E, Ménétret JF, Gumbart JC, Ludtke SJ, Li W, Whynot A, Rapoport TA, Akey CW. Structure of the SecY channel during initiation of protein translocation. Nature. 506: 102-6. PMID 24153188 DOI: 10.1038/Nature12720  0.447
2014 Shen G, Zhang H, Cui W, Sadler E, Gross M, Li W. Warfarin Inhibits Vitamin K Epoxide Reductase By Specifically Blocking at a Conformational and Redox State Blood. 124: 4214-4214. DOI: 10.1182/Blood.V124.21.4214.4214  0.522
2011 Li W, Li F. Cross-crystal averaging with search models to improve molecular replacement phases. Structure (London, England : 1993). 19: 155-61. PMID 21300285 DOI: 10.1016/J.Str.2010.12.007  0.653
2010 Schulman S, Wang B, Li W, Rapoport TA. Vitamin K epoxide reductase prefers ER membrane-anchored thioredoxin-like redox partners. Proceedings of the National Academy of Sciences of the United States of America. 107: 15027-32. PMID 20696932 DOI: 10.1073/Pnas.1009972107  0.52
2010 Li W, Schulman S, Dutton RJ, Boyd D, Beckwith J, Rapoport TA. Structure of a bacterial homologue of vitamin K epoxide reductase. Nature. 463: 507-12. PMID 20110994 DOI: 10.1038/Nature08720  0.533
2009 Wu K, Li W, Peng G, Li F. Crystal structure of NL63 respiratory coronavirus receptor-binding domain complexed with its human receptor. Proceedings of the National Academy of Sciences of the United States of America. 106: 19970-4. PMID 19901337 DOI: 10.1073/Pnas.0908837106  0.577
2007 Ye J, Cho SH, Fuselier J, Li W, Beckwith J, Rapoport TA. Crystal structure of an unusual thioredoxin protein with a zinc finger domain. The Journal of Biological Chemistry. 282: 34945-51. PMID 17913712 DOI: 10.1074/Jbc.M704044200  0.486
2007 Li W, Schulman S, Boyd D, Erlandson K, Beckwith J, Rapoport TA. The plug domain of the SecY protein stabilizes the closed state of the translocation channel and maintains a membrane seal. Molecular Cell. 26: 511-21. PMID 17531810 DOI: 10.1016/J.Molcel.2007.05.002  0.462
2006 Zimmer J, Li W, Rapoport TA. A novel dimer interface and conformational changes revealed by an X-ray structure of B. subtilis SecA. Journal of Molecular Biology. 364: 259-65. PMID 16989859 DOI: 10.1016/J.Jmb.2006.08.044  0.505
2006 Kamtekar S, Ho RS, Cocco MJ, Li W, Wenwieser SV, Boocock MR, Grindley ND, Steitz TA. Implications of structures of synaptic tetramers of gamma delta resolvase for the mechanism of recombination. Proceedings of the National Academy of Sciences of the United States of America. 103: 10642-7. PMID 16807292 DOI: 10.1073/Pnas.0604062103  0.619
2005 Li W, Kamtekar S, Xiong Y, Sarkis GJ, Grindley ND, Steitz TA. Structure of a synaptic gammadelta resolvase tetramer covalently linked to two cleaved DNAs. Science (New York, N.Y.). 309: 1210-5. PMID 15994378 DOI: 10.2210/Pdb1Zr2/Pdb  0.563
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