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Joshua G. Pierce, Ph.D. - Publications

Affiliations: 
1999-2008 Chemistry University of Pittsburgh, Pittsburgh, PA, United States 
 2008-2011 Chemistry Scripps Research Institute 
 2012- Chemistry North Carolina State University, Raleigh, NC 
Area:
Organic Synthesis, Chemical Microbiology
Website:
piercegroup.wordpress.ncsu.edu
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52 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2022 Qiu X, Pierce JG. Total Synthesis of Bipolamine I. Journal of the American Chemical Society. PMID 35786918 DOI: 10.1021/jacs.2c06015  0.337
2022 Pandit S, Palvai SK, Massaro N, Pierce J, Brudno Y. Tissue-reactive drugs enable materials-free local depots. Journal of Controlled Release : Official Journal of the Controlled Release Society. PMID 35077743 DOI: 10.1016/j.jconrel.2022.01.023  0.714
2021 Massaro NP, Pierce JG. Rapid synthesis of the core scaffold of crinane and haemanthamine through a multi-component approach. Tetrahedron Letters. 75. PMID 34176982 DOI: 10.1016/j.tetlet.2021.153201  0.763
2021 Valdes-Pena MA, Massaro NP, Lin YC, Pierce JG. Leveraging Marine Natural Products as a Platform to Tackle Bacterial Resistance and Persistence. Accounts of Chemical Research. PMID 33733746 DOI: 10.1021/acs.accounts.1c00007  0.763
2020 Natalia Gonzalez S, Mills JJ, Maugeri D, Olaya C, Laguera BL, Enders JR, Sherman J, Rodriguez A, Pierce JG, José Cazzulo J, D'Antonio EL. Design, Synthesis, and Evaluation of Substrate - Analogue Inhibitors of Trypanosoma cruzi Ribose 5-Phosphate Isomerase type B. Bioorganic & Medicinal Chemistry Letters. 127723. PMID 33249135 DOI: 10.1016/j.bmcl.2020.127723  0.709
2020 Massaro NP, Pierce JG. Stereoselective, Multicomponent Approach to Quaternary Substituted Hydroindole Scaffolds. Organic Letters. 22: 5079-5084. PMID 32610919 DOI: 10.1021/Acs.Orglett.0C01650  0.762
2020 Lin YC, Ribaucourt A, Moazami Y, Pierce JG. Concise Synthesis and Antimicrobial Evaluation of the Guanidinium Alkaloid Batzelladine D: Development of a Stereodivergent Strategy. Journal of the American Chemical Society. PMID 32396001 DOI: 10.1021/Jacs.0C04091  0.417
2020 Luckring EJ, Parker PD, Hani H, Grace MH, Lila MA, Pierce JG, Adin CA. In Vitro Evaluation of a Novel Synthetic Bilirubin Analog as an Antioxidant and Cytoprotective Agent for Pancreatic Islet Transplantation. Cell Transplantation. 29: 963689720906417. PMID 32323568 DOI: 10.1177/0963689720906417  0.305
2020 Cholewczynski AE, Williams PC, Pierce JG. Stereocontrolled Synthesis of (±)-Melokhanine E via an Intramolecular Formal [3 + 2] Cycloaddition. Organic Letters. PMID 31908171 DOI: 10.1021/Acs.Orglett.9B04546  0.399
2019 Frohock BH, Gilbertie JM, Daiker JC, Schnabel LV, Pierce JG. 5-Benzylidene-4-Oxazolidinones are Synergistic with Antibiotics for the Treatment of Staphylococcus aureus Biofilms. Chembiochem : a European Journal of Chemical Biology. PMID 31688982 DOI: 10.1002/Cbic.201900633  0.326
2019 Robinson KR, Mills JJ, Pierce JG. Expanded Structure-Activity Studies of Lipoxazolidinone Antibiotics. Acs Medicinal Chemistry Letters. 10: 374-377. PMID 30891143 DOI: 10.1021/Acsmedchemlett.9B00015  0.752
2018 Mills J, Robinson K, Zehnder T, Pierce JG. Synthesis and Biological Evaluation of the Antimicrobial Natural Product Lipoxazolidinone A. Angewandte Chemie (International Ed. in English). PMID 29845720 DOI: 10.1002/Anie.201805078  0.764
2018 Cusumano AQ, Pierce JG. 3-Hydroxy-1,5-dihydro-2H-pyrrol-2-ones as novel antibacterial scaffolds against methicillin-resistant Staphylococcus aureus. Bioorganic & Medicinal Chemistry Letters. PMID 29525221 DOI: 10.1016/J.Bmcl.2018.02.047  0.372
2018 Parker PD, Ge Y, Pierce JG. Coupling of thioamides with 4-bromocrotonate esters and subsequent conjugate addition for the rapid one-pot synthesis of functionalized thiazolines Tetrahedron Letters. 59: 277-279. DOI: 10.1016/J.Tetlet.2017.12.043  0.42
2017 Cusumano AQ, Boudreau MW, Pierce JG. Direct Access to Highly Functionalized Heterocycles through the Condensation of Cyclic Imines and α-Oxoesters. The Journal of Organic Chemistry. 82: 13714-13721. PMID 29206454 DOI: 10.1021/Acs.Joc.7B02572  0.705
2017 Parker PD, Lemercier BC, Pierce JG. Synthesis of Quaternary-Substituted Thiazolines via Halocyclization of S-Allyl Thioimidate Salts. The Journal of Organic Chemistry. PMID 29064693 DOI: 10.1021/Acs.Joc.7B02299  0.39
2017 Shymanska NV, Pierce JG. Stereoselective Synthesis of Quaternary Pyrrolidine-2,3-diones and β-Amino Acids. Organic Letters. PMID 28537396 DOI: 10.1021/Acs.Orglett.7B01185  0.382
2017 Edwards GA, Shymanska NV, Pierce JG. 5-Benzylidene-4-oxazolidinones potently inhibit biofilm formation in Methicillin-resistant Staphylococcus aureus. Chemical Communications (Cambridge, England). PMID 28537316 DOI: 10.1039/C7Cc03626D  0.329
2017 Shi Y, Moazami Y, Pierce JG. Structure, synthesis and biological properties of the pentacyclic guanidinium alkaloids. Bioorganic & Medicinal Chemistry. PMID 28404523 DOI: 10.1016/J.Bmc.2017.03.015  0.419
2017 Snieckus V, Jiao W, Shymanska N, Pierce JG. Stereoselective Synthesis of Pyrrolidine-2,3-diones by a Claisen Rearrangement Synfacts. 13: 799-2964. DOI: 10.1055/S-0036-1590739  0.404
2016 Shi Y, Pierce JG. Stereocontrolled Synthesis of (+)-Plagiogyrin A. Organic Letters. PMID 27690467 DOI: 10.1021/Acs.Orglett.6B02629  0.38
2016 Parker PD, Pierce JG. Synthesis of 1,2,4-Oxadiazoles via DDQ-Mediated Oxidative Cyclization of Amidoximes Synthesis (Germany). 48: 1902-1909. DOI: 10.1055/S-0035-1561597  0.389
2016 Lemercier BC, Pierce JG. Thiohydroximic acids: Versatile reagents for organic synthesis Synlett. 27: 181-189. DOI: 10.1055/S-0035-1560700  0.384
2015 Lemercier BC, Pierce JG. Synthesis of 1,4,2-Oxathiazoles via Oxidative Cyclization of Thiohydroximic Acids. Organic Letters. 17: 4542-5. PMID 26332015 DOI: 10.1021/Acs.Orglett.5B02256  0.36
2015 Moazami Y, Gulledge TV, Laster SM, Pierce JG. Synthesis and biological evaluation of a series of fatty acid amides from Echinacea. Bioorganic & Medicinal Chemistry Letters. 25: 3091-4. PMID 26105195 DOI: 10.1016/J.Bmcl.2015.06.024  0.366
2015 Shymanska NV, An IH, Guevara-Zuluaga S, Pierce JG. Rapid synthesis and antimicrobial activity of novel 4-oxazolidinone heterocycles. Bioorganic & Medicinal Chemistry Letters. PMID 26099542 DOI: 10.1016/J.Bmcl.2015.06.003  0.455
2015 Shi Y, Pierce JG. Synthesis of the 5,6-dihydroxymorpholin-3-one fragment of monanchocidin A. Organic Letters. 17: 968-71. PMID 25642987 DOI: 10.1021/Acs.Orglett.5B00069  0.397
2015 Pierce J, Shymanska N, Edwards G. Marine natural products synthesis as a driving force for chemical and biological discovery Planta Medica. 81. DOI: 10.1055/S-0035-1556104  0.354
2015 Pierce J, Moazami Y. Synthesis of 2,3-Dihydro-1,3-oxazin-4-ones via a Mild Formal [4+2] Cycloaddition of Acylketenes with Aldimines Synthesis. 47: 3363-3370. DOI: 10.1055/S-0034-1378788  0.404
2014 Shymanska NV, An IH, Pierce JG. A rapid synthesis of 4-oxazolidinones: total synthesis of synoxazolidinones A and B. Angewandte Chemie (International Ed. in English). 53: 5401-4. PMID 24711268 DOI: 10.1002/Anie.201402310  0.465
2014 Lemercier BC, Pierce JG. Synthesis of thiazolines by copper catalyzed aminobromination of thiohydroximic acids. Organic Letters. 16: 2074-6. PMID 24645640 DOI: 10.1021/Ol500588V  0.373
2014 Lemercier BC, Pierce JG. Synthesis of thiohydroxamic acids and thiohydroximic acid derivatives. The Journal of Organic Chemistry. 79: 2321-30. PMID 24555829 DOI: 10.1021/Jo500080X  0.351
2012 Miller B, Mao S, Rosenker KM, Pierce JG, Wipf P. Synthesis of a library of tricyclic azepinoisoindolinones. Beilstein Journal of Organic Chemistry. 8: 1091-7. PMID 23019435 DOI: 10.3762/Bjoc.8.120  0.546
2012 Okano A, James RC, Pierce JG, Xie J, Boger DL. Silver(I)-promoted conversion of thioamides to amidines: divergent synthesis of a key series of vancomycin aglycon residue 4 amidines that clarify binding behavior to model ligands. Journal of the American Chemical Society. 134: 8790-3. PMID 22568755 DOI: 10.1021/Ja302808P  0.479
2012 James RC, Pierce JG, Okano A, Xie J, Boger DL. Redesign of glycopeptide antibiotics: back to the future. Acs Chemical Biology. 7: 797-804. PMID 22330049 DOI: 10.1021/Cb300007J  0.495
2012 Xie J, Okano A, Pierce JG, James RC, Stamm S, Crane CM, Boger DL. Total synthesis of [Ψ[C(═S)NH]Tpg4]vancomycin aglycon, [Ψ[C(═NH)NH]Tpg4]vancomycin aglycon, and related key compounds: reengineering vancomycin for dual D-Ala-D-Ala and D-Ala-D-Lac binding. Journal of the American Chemical Society. 134: 1284-97. PMID 22188323 DOI: 10.1021/Ja209937S  0.513
2011 Xie J, Pierce JG, James RC, Okano A, Boger DL. A redesigned vancomycin engineered for dual D-Ala-D-ala And D-Ala-D-Lac binding exhibits potent antimicrobial activity against vancomycin-resistant bacteria. Journal of the American Chemical Society. 133: 13946-9. PMID 21823662 DOI: 10.1021/Ja207142H  0.451
2011 Frantz MC, Pierce JG, Pierce JM, Kangying L, Qingwei W, Johnson M, Wipf P. Large-scale asymmetric synthesis of the bioprotective agent JP4-039 and analogs. Organic Letters. 13: 2318-21. PMID 21452836 DOI: 10.1021/Ol200567P  0.484
2011 Frantz M-, Pierce JG, Pierce JM, Kangying L, Qingwei W, Johnson M, Wipf P. Asymmetric Synthesis of the Bioprotective Agent JP4-039 Synfacts. 2011: 700-700. DOI: 10.1055/S-0030-1260483  0.479
2010 Crane CM, Pierce JG, Leung SS, Tirado-Rives J, Jorgensen WL, Boger DL. Synthesis and evaluation of selected key methyl ether derivatives of vancomycin aglycon. Journal of Medicinal Chemistry. 53: 7229-35. PMID 20853900 DOI: 10.1021/Jm100946E  0.491
2009 Rajagopalan MS, Gupta K, Epperly MW, Franicola D, Zhang X, Wang H, Zhao H, Tyurin VA, Pierce JG, Kagan VE, Wipf P, Kanai AJ, Greenberger JS. The mitochondria-targeted nitroxide JP4-039 augments potentially lethal irradiation damage repair. In Vivo (Athens, Greece). 23: 717-26. PMID 19779106  0.315
2008 Pierce JG, Kasi D, Fushimi M, Cuzzupe A, Wipf P. Synthesis of hydroxylated bicyclic amino acids from L-tyrosine: octahydro-1H-indole carboxylates. The Journal of Organic Chemistry. 73: 7807-10. PMID 18767800 DOI: 10.1021/Jo801552J  0.443
2008 Gupta K, Epperly MW, Franicola D, Zhang X, Pierce JG, Wipf P, Greenberger J. Mitigation of Irradiation Induced Potentially Lethal Damage (PLD) in Hematopoietic Cells by Mitochondrial Localized GS-Nitroxide, JP4-039 Blood. 112: 4725-4725. DOI: 10.1182/Blood.V112.11.4725.4725  0.385
2008 Epperly MW, Pierce JG, Dixon T, Franicola D, Nie S, Zhang X, Vlasova II, Wipf P, Kagan V, Greenberger J. A Mitochondrially Targeted Nitroxide JP4-039 Protects and Mitigates against Total Body Irradiation Induced Hematopoietic Syndrome Blood. 112: 4721-4721. DOI: 10.1182/Blood.V112.11.4721.4721  0.415
2008 Epperly M, Pierce J, Dixon T, Franicola D, Wipf P, Greenberger J. The Mitochondrial Targeted GS-Nitroxide JP4-039 is Radioprotective In Vitro and In Vivo International Journal of Radiation Oncology*Biology*Physics. 72: S82. DOI: 10.1016/J.Ijrobp.2008.06.952  0.39
2008 Pierce JG, Waller DL, Wipf P. ChemInform Abstract: Synthesis of Functionalized Isoindolinones: Addition of in situ Generated Organoalanes to Acyliminium Ions. Cheminform. 39. DOI: 10.1002/chin.200806106  0.372
2007 Pierce JG, Waller DL, Wipf P. Synthesis of Functionalized Isoindolinones: Addition of In Situ Generated Organoalanes to Acyliminium Ions. Journal of Organometallic Chemistry. 692: 4618-4629. PMID 19684878 DOI: 10.1016/J.Jorganchem.2007.05.035  0.504
2007 Wipf P, Pierce J. Synthesis of the α-C-Glycoside Analogue of KRN7000 Synfacts. 2007: 0001-0001. DOI: 10.1055/s-2006-955651  0.383
2006 Wipf P, Pierce JG. Expedient synthesis of the alpha-C-glycoside analogue of the immunostimulant galactosylceramide (KRN7000). Organic Letters. 8: 3375-8. PMID 16836409 DOI: 10.1021/Ol0613057  0.473
2005 Wipf P, Pierce JG. Synthesis of homoallylic amines by hydrozirconation-imine addition of allenes. Organic Letters. 7: 3537-40. PMID 16048336 DOI: 10.1021/Ol051266J  0.478
2005 Wipf P, Pierce JG, Zhuang N. Silver(I)-catalyzed addition of zirconocenes to glycal epoxides. A new synthesis of alpha-C-glycosides. Organic Letters. 7: 483-5. PMID 15673270 DOI: 10.1021/Ol0475414  0.455
2003 Wipf P, Pierce JG, Wang X. Investigation of ligand loading and asymmetric amplification in CHAOx-catalyzed asymmetric diethylzinc additions Tetrahedron Asymmetry. 14: 3605-3611. DOI: 10.1016/J.Tetasy.2003.07.022  0.432
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