| Year |
Citation |
Score |
| 2023 |
Limberakis C, Smith AC, Bagley SW, Yayla HG, Kung DW, Griffith DA. Convergent Syntheses of Isomeric Imidazolospiroketones as Templates for Acetyl-CoA Carboxylase (ACC) Inhibitors. The Journal of Organic Chemistry. PMID 37751412 DOI: 10.1021/acs.joc.3c01374 |
0.305 |
|
| 2019 |
Dechert-Schmitt A, Garnsey MR, Wisniewska HM, Murray JI, Lee T, Kung DW, Sach N, Blackmond DG. Highly Modular Synthesis of 1,2-Diketones via Multicomponent Coupling Reactions of Isocyanides as CO Equivalents Acs Catalysis. 9: 4508-4515. DOI: 10.1021/Acscatal.9B00581 |
0.376 |
|
| 2018 |
Ryder T, Calabrese MF, Walker GS, Cameron KO, Reyes AR, Borzilleri KA, Delmore J, Miller RA, Kurumbail RG, Ward J, Kung DW, Brown JA, Edmonds DJ, Eng H, Wolford AC, et al. Acyl Glucuronide Metabolites of 6-Chloro-5-[4-(1-hydroxycyclobutyl)phenyl]-1H-indole-3-carboxylic Acid (PF-06409577) and Related Indole-3-carboxylic Acid Derivatives are Direct Activators of Adenosine Monophosphate-activated Protein Kinase (AMPK). Journal of Medicinal Chemistry. PMID 30036059 DOI: 10.1021/Acs.Jmedchem.8B00807 |
0.368 |
|
| 2018 |
Smith AC, Kung DW, Shavnya A, Brandt TA, Dent PD, Genung NE, Cabral S, Panteleev J, Herr M, Yip KN, Aspnes GE, Conn EL, Dowling MS, Edmonds DJ, Edmonds ID, et al. Evolution of the Synthesis of AMPK Activators for the Treatment of Diabetic Nephropathy: From Three Preclinical Candidates to the Investigational New Drug PF-06409577 Organic Process Research & Development. 22: 681-696. DOI: 10.1021/Acs.Oprd.8B00059 |
0.324 |
|
| 2018 |
Bader SJ, Herr M, Aspnes GE, Cabral S, Li Q, Bian J, Coffey SB, Dowling MS, Fernando DP, Jiao W, Lavergne SY, Kung DW. Route Selection and Optimization in the Synthesis of Two Imidazopyridine Inhibitors of DGAT-2 Organic Process Research & Development. 22: 360-367. DOI: 10.1021/Acs.Oprd.8B00005 |
0.341 |
|
| 2016 |
Smith AC, Cabral S, Kung DW, Rose CR, Southers JA, Garcia-Irizarry CN, Damon DB, Bagley SW, Griffith DA. The synthesis of methyl-substituted spirocyclic piperidine-azetidine (2,7-diazaspiro[3.5]nonane) and spirocyclic piperidine-pyrrolidine (2,8-diazaspiro[4.5]decane) ring systems. The Journal of Organic Chemistry. PMID 27056793 DOI: 10.1021/Acs.Joc.5B02890 |
0.435 |
|
| 2016 |
Dechert-Schmitt A, Cabral S, Kung D. Development of an O-Vinylation–Ring-Closing Metathesis Strategy to Access 3,3′-3,4-Dihydropyrans Synlett. 27: 2611-2615. DOI: 10.1055/S-0036-1588615 |
0.378 |
|
| 2015 |
Ruggeri RB, Buckbinder L, Bagley SW, Carpino PA, Conn EL, Dowling MS, Fernando DP, Jiao W, Kung DW, Orr ST, Qi Y, Rocke BN, Smith A, Warmus JS, Zhang Y, et al. Discovery of 2-(6-(5-Chloro-2-methoxyphenyl)-4-oxo-2-thioxo-3,4-dihydropyrimidin-1(2H)-yl)acetamide (PF-06282999): A Highly Selective Mechanism-Based Myeloperoxidase Inhibitor for the Treatment of Cardiovascular Diseases. Journal of Medicinal Chemistry. PMID 26509551 DOI: 10.1021/Acs.Jmedchem.5B00963 |
0.36 |
|
| 2015 |
Panteleev J, Maguire RJ, Kung DW. Alkylation of nitrogen-containing heterocycles via in situ sulfonyl transfer Synlett. 26: 953-959. DOI: 10.1055/S-0034-1380690 |
0.383 |
|
| 2012 |
Bagley SW, Southers JA, Cabral S, Rose CR, Bernhardson DJ, Edmonds DJ, Polivkova J, Yang X, Kung DW, Griffith DA, Bader SJ. Synthesis of 7-oxo-dihydrospiro[indazole-5,4'-piperidine] acetyl-CoA carboxylase inhibitors. The Journal of Organic Chemistry. 77: 1497-506. PMID 22239115 DOI: 10.1021/Jo202377G |
0.454 |
|
| 2012 |
Limberakis C, Li J, Balan G, Griffith DA, Kung DW, Rose C, Vrieze D. Complementary α-alkylation approaches for a sterically hindered spiro[pyrazolopyranpiperidine]ketone Tetrahedron Letters. 53: 2543-2547. DOI: 10.1016/J.Tetlet.2012.03.030 |
0.53 |
|
| 2010 |
Li J, Kung DW, Griffith DA. Synthesis of 5-hydroxyquinolines Tetrahedron Letters. 51: 3876-3878. DOI: 10.1016/J.Tetlet.2010.05.058 |
0.319 |
|
| 2010 |
Myers AG, Zhong B, Movassaghi M, Kung DW, Lanman BA, Kwon S. ChemInform Abstract: Synthesis of Highly Epimerizable N-Protected α-Amino Aldehydes of High Enantiomeric Excess. Cheminform. 31: no-no. DOI: 10.1002/chin.200020061 |
0.811 |
|
| 2010 |
Myers AG, Kung DW, Zhong B, Movassaghi M, Kwon S. ChemInform Abstract: Preparation of Chiral, C-Protected α-Amino Aldehydes of High Optical Purity and Their Use as Condensation Components in a Linear Synthesis Strategy. Cheminform. 31: no-no. DOI: 10.1002/chin.200002109 |
0.775 |
|
| 2010 |
Myers AG, Schnider P, Kwon S, Kung DW. ChemInform Abstract: Greatly Simplified Procedures for the Synthesis of α-Amino Acids by the Direct Alkylation of Pseudoephedrine Glycinamide Hydrate. Cheminform. 30: no-no. DOI: 10.1002/chin.199937215 |
0.746 |
|
| 2010 |
MYERS AG, GLEASON JL, YOON T, KUNG DW. ChemInform Abstract: Highly Practical Methodology for the Synthesis of D- and L-α- Amino Acids, N-Protected α-Amino Acids, and N-Methyl-α- amino Acids. Cheminform. 28: no-no. DOI: 10.1002/chin.199719219 |
0.689 |
|
| 2001 |
Myers AG, Zhong B, Kung DW, Movassaghi M, Lanman BA, Kwon S. ChemInform Abstract: Synthesis of C-Protected α-Amino Aldehydes of High Enantiomeric Excess from Highly Epimerizable N-Protected α-Amino Aldehydes. Cheminform. 32: no-no. DOI: 10.1002/chin.200108097 |
0.813 |
|
| 2000 |
Myers AG, Zhong B, Kung DW, Movassaghi M, Lanman BA, Kwon S. Synthesis of C-protected alpha-amino aldehydes of high enantiomeric excess from highly epimerizable N-protected alpha-amino aldehydes. Organic Letters. 2: 3337-40. PMID 11029204 DOI: 10.1021/Ol006427S |
0.712 |
|
| 2000 |
Myers AG, Kung DW. One-step construction of the pentacyclic skeleton of saframycin A from a "Trimer" of alpha-amino aldehydes. Organic Letters. 2: 3019-22. PMID 10986097 DOI: 10.1021/Ol0063398 |
0.614 |
|
| 2000 |
Myers AG, Kung DW, Zhong B. Observations concerning the existence and reactivity of free α-amino aldehydes as chemical intermediates: Evidence for epimerization-free adduct formation with various nucleophiles [11] Journal of the American Chemical Society. 122: 3236-3237. DOI: 10.1021/Ja000136X |
0.774 |
|
| 2000 |
Myers AG, Zhong B, Movassaghi M, Kung DW, Lanman BA, Kwon S. Synthesis of highly epimerizable N-protected α-amino aldehydes of high enantiomeric excess Tetrahedron Letters. 41: 1359-1362. DOI: 10.1016/S0040-4039(99)02293-5 |
0.74 |
|
| 2000 |
Myers AG, Kung DW. One-step construction of the pentacyclic skeleton of saframycin A from a "trimer" of α-amino aldehydes Organic Letters. 2: 3019-3022. |
0.668 |
|
| 1999 |
Myers AG, Schnider P, Kwon S, Kung DW. Greatly Simplified Procedures for the Synthesis of alpha-Amino Acids by the Direct Alkylation of Pseudoephedrine Glycinamide Hydrate. The Journal of Organic Chemistry. 64: 3322-3327. PMID 11674437 DOI: 10.1021/Jo990341Z |
0.702 |
|
| 1999 |
Myers AG, Schnider P, Kwon S, Kung DW. Greatly simplified procedures for the synthesis of α-amino acids by the direct alkylation of pseudoephedrine glycinamide hydrate Journal of Organic Chemistry. 64: 3322-3327. DOI: 10.1021/jo990341z |
0.743 |
|
| 1999 |
Myers AG, Kung DW. A concise, stereocontrolled synthesis of (-)-saframycin A by the directed condensation of α-amino aldehyde precursors [1] Journal of the American Chemical Society. 121: 10828-10829. DOI: 10.1021/Ja993079K |
0.728 |
|
| 1999 |
Myers AG, Kung DW, Zhong B, Movassaghi M, Kwon S. Preparation of chiral, C-protected α-amino aldehydes of high optical purity and their use as condensation components in a linear synthesis strategy Journal of the American Chemical Society. 121: 8401-8402. DOI: 10.1021/Ja9911824 |
0.787 |
|
| 1997 |
Myers AG, Gleason JL, Yoon T, Kung DW. Highly practical methodology for the synthesis of D- and L-α-amino acids, N-protected α-amino acids, and N-methyl-α-amino acids Journal of the American Chemical Society. 119: 656-673. DOI: 10.1021/Ja9624073 |
0.801 |
|
| 1997 |
Evans DA, Carter PH, Dinsmore CJ, Barrow JC, Katz JL, Kung DW. Mild nitrosation and hydrolysis of polyfunctional amides Tetrahedron Letters. 38: 4535-4538. DOI: 10.1016/S0040-4039(97)00972-6 |
0.379 |
|
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