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Tae-gyu Nam, Ph.D. - Publications

Affiliations: 
2006 Vanderbilt University, Nashville, TN 
Area:
free radical chemistry
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35 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Chaudhary CL, Chaudhary P, Dahal S, Bae D, Nam TG, Kim JA, Jeong BS. Inhibition of colitis by ring-modified analogues of 6-acetamido-2,4,5-trimethylpyridin-3-ol. Bioorganic Chemistry. 103: 104130. PMID 32745758 DOI: 10.1016/J.Bioorg.2020.104130  0.38
2020 Lee H, Lee JS, Cho HJ, Lee YJ, Kim ES, Kim SK, Nam TG, Jeong BS, Kim JA. Antioxidant Analogue 6-Amino-2,4,5-Trimethylpyridin-3-ol Ameliorates Experimental Colitis in Mice. Digestive Diseases and Sciences. PMID 32361923 DOI: 10.1007/S10620-020-06267-6  0.34
2020 Chaudhary CL, Gurung P, Jang S, Banskota S, Nam TG, Kim JA, Jeong BS. Synthesis, activity and mechanism of alkoxy-, carbamato-, sulfonamido-, thioureido-, and ureido-derivatives of 2,4,5-trimethylpyridin-3-ol against inflammatory bowel disease. Journal of Enzyme Inhibition and Medicinal Chemistry. 35: 1-20. PMID 31619080 DOI: 10.1080/14756366.2019.1677637  0.304
2020 Park SW, Kang HE, Yun W, Lee SY, Nam T. A facile synthesis of epinastine HCl via dehydroepinastine intermediate Tetrahedron Letters. 61: 151451. DOI: 10.1016/J.Tetlet.2019.151451  0.328
2019 Choi H, Yun W, Lee J, Jang S, Park SW, Kim DH, Seon KP, Hyun J, Jeong K, Ku J, Nam T. Synthesis and anti-endoplasmic reticulum stress activity of N-substituted-2-arylcarbonylhydrazinecarbothioamides Medicinal Chemistry Research. 28: 2142-2152. DOI: 10.1007/S00044-019-02442-1  0.347
2018 Jang SW, Cho CH, Jung YS, Rha C, Nam TG, Kim DO, Lee YG, Baek NI, Park CS, Lee BH, Lee SY, Shin HS, Seo DH. Enzymatic synthesis of α-flavone glucoside via regioselective transglucosylation by amylosucrase from Deinococcus geothermalis. Plos One. 13: e0207466. PMID 30452462 DOI: 10.1371/Journal.Pone.0207466  0.329
2018 Gautam J, Banskota S, Chaudhary P, Dahal S, Kim DG, Kang HE, Lee IH, Nam TG, Jeong BS, Kim JA. Antitumor activity of BJ-1207, a 6-amino-2,4,5-trimethylpyridin-3-ol derivative, in human lung cancer. Chemico-Biological Interactions. PMID 30125546 DOI: 10.1016/J.Cbi.2018.08.007  0.357
2018 Park SW, Kim SH, Song J, Park GY, Kim D, Nam TG, Hong KB. Hypervalent iodine-mediated Ritter-type amidation of terminal alkenes: The synthesis of isoxazoline and pyrazoline cores. Beilstein Journal of Organic Chemistry. 14: 1028-1033. PMID 29977375 DOI: 10.3762/Bjoc.14.89  0.318
2017 Bae D, Gautam J, Jang H, Banskota S, Lee SY, Jeong MJ, Kim AS, Kim HC, Lee IH, Nam TG, Kim JA, Jeong BS. Protective effects of 6-ureido/thioureido-2,4,5-trimethylpyridin-3-ols against 4-hydroxynonenal-induced cell death in adult retinal pigment epithelial-19 cells. Bioorganic & Medicinal Chemistry Letters. PMID 29208521 DOI: 10.1016/J.Bmcl.2017.11.046  0.386
2017 Kim DG, Kang Y, Lee H, Lee EK, Nam TG, Kim JA, Jeong BS. Corrigendum to "6-Amino-2,4,5-trimethylpyridin-3-ols: A new general synthetic route and antiangiogenic activity" [Eur. J. Med. Chem. 74 (2014) 126-139]. European Journal of Medicinal Chemistry. PMID 28988929 DOI: 10.1016/J.Ejmech.2017.09.042  0.302
2017 Lee DS, Nam TG, Jeong BS, Jeong GS. Retraction notice to "BJ-1103, 6-aminopyridin-3-ol skeletal compound, modulates neuroprotective and anti-neuroinflammatory effects in murine hippocampal and microglial cells via Nrf2-mediated heme oxygenase-1 expression" [Neurosci. Lett. 627 (2016) 42-50]. Neuroscience Letters. 641: 107. PMID 28190428 DOI: 10.1016/J.Neulet.2016.10.046  0.313
2016 Banskota S, Kang HE, Kim DG, Park SW, Jang H, Karmacharya U, Jeong BS, Kim JA, Nam TG. In vitro and in vivo inhibitory activity of 6-amino-2,4,5-trimethylpyridin-3-ols against inflammatory bowel disease. Bioorganic & Medicinal Chemistry Letters. PMID 27597248 DOI: 10.1016/J.Bmcl.2016.08.075  0.335
2016 Lee DS, Nam TG, Jeong BS, Jeong GS. BJ-1103, 6-aminopyridin-3-ol skeletal compound, modulates neuroprotective and anti-neuroinflammatory effects in murine hippocampal and microglial cells via Nrf2-mediated heme oxygenase-1 expression. Neuroscience Letters. PMID 27238747 DOI: 10.1016/J.Neulet.2016.05.056  0.407
2016 Lee DS, Nam TG, Jeong BS, Jeong GS. The Aminopyridinol Derivative BJ-1201 Protects Murine Hippocampal Cells against Glutamate-Induced Neurotoxicity via Heme Oxygenase-1. Molecules (Basel, Switzerland). 21. PMID 27164069 DOI: 10.3390/Molecules21050594  0.377
2016 Shah S, Lee C, Choi H, Gautam J, Jang H, Kim GJ, Lee YJ, Chaudhary CL, Park SW, Nam TG, Kim JA, Jeong BS. 5-Hydroxy-7-azaindolin-2-one, a novel hybrid of pyridinol and sunitinib: design, synthesis and cytotoxicity against cancer cells. Organic & Biomolecular Chemistry. PMID 27145715 DOI: 10.1039/C6Ob00406G  0.347
2016 Park SW, Choi H, Lee JH, Lee YJ, Ku JM, Lee SY, Nam TG. IBX-mediated synthesis of indazolone via oxidative N-N bond formation and unexpected formation of quinazolin-4-one: in situ generation of formaldehyde from dimethoxyethane. Archives of Pharmacal Research. PMID 26780246 DOI: 10.1007/S12272-016-0706-Z  0.368
2015 Lee SY, Baek N, Nam TG. Natural, semisynthetic and synthetic tyrosinase inhibitors. Journal of Enzyme Inhibition and Medicinal Chemistry. 1-13. PMID 25683082 DOI: 10.3109/14756366.2015.1004058  0.318
2015 Jin CR, Cho CH, Nam TG, Cho YS, Kim DO. Effects of hot air drying on the antioxidant capacity of actinidia arguta × A. deliciosa cv. Mansoo, a hardy kiwifruit Korean Journal of Food Science and Technology. 47: 539-543. DOI: 10.9721/Kjfst.2015.47.4.539  0.353
2014 Lee H, Kim DG, Banskota S, Lee YK, Nam TG, Kim JA, Jeong BS. Pyridoxine-derived bicyclic amido-, ureido-, and carbamato-pyridinols: synthesis and antiangiogenic activities. Organic & Biomolecular Chemistry. 12: 8702-10. PMID 25255328 DOI: 10.1039/C4Ob01221F  0.397
2014 Lee H, Banskota S, Kim DG, Been JH, Jin YJ, Gautam J, Jang H, Nam TG, Kim JA, Jeong BS. Synthesis and antiangiogenic activity of 6-amido-2,4,5-trimethylpyridin-3-ols. Bioorganic & Medicinal Chemistry Letters. 24: 3131-6. PMID 24894557 DOI: 10.1016/J.Bmcl.2014.05.005  0.426
2014 Kim DG, Kang Y, Lee H, Lee EK, Nam TG, Kim JA, Jeong BS. 6-Amino-2,4,5-trimethylpyridin-3-ols: a new general synthetic route and antiangiogenic activity. European Journal of Medicinal Chemistry. 78: 126-39. PMID 24681390 DOI: 10.1016/J.Ejmech.2014.03.045  0.36
2014 Kadayat TM, Kim MJ, Nam T, Park P, Lee E. Thieny/Furanyl-hydroxyphenylpropenones as Inhibitors of LPS-induced ROS and NO Production in RAW 264.7 Macrophages, and Their Structure-Activity Relationship Study Bulletin of the Korean Chemical Society. 35: 2481-2486. DOI: 10.5012/Bkcs.2014.35.8.2481  0.334
2014 Lee CR, Lee SY, Nam TG. Succinct synthesis of bosentan utilizing glycol Mono-THP ether Synthetic Communications. 44: 2488-2493. DOI: 10.1080/00397911.2014.904881  0.33
2014 Lee H, Lee Y, Kim D, Son M, Nam T, Jeong B. Tocopherol side chain synthesis via asymmetric organocatalytic transfer hydrogenation and convenient measurement of stereoselectivity Tetrahedron Letters. 55: 5895-5897. DOI: 10.1016/J.Tetlet.2014.08.085  0.315
2013 Jeong KW, Ku JM, Park MW, Park SM, Yang JE, Nam TG. Hydroxynaphthoic acids identified in a high throughput screening potently ameliorate endoplasmic reticulum stress as novel chemical chaperones. Chemical & Pharmaceutical Bulletin. 61: 740-6. PMID 23812398 DOI: 10.1248/Cpb.C13-00251  0.326
2011 Nam TG. Lipid peroxidation and its toxicological implications. Toxicological Research. 27: 1-6. PMID 24278542 DOI: 10.5487/Tr.2011.27.1.001  0.409
2011 Nam TG, Ku JM, Rector CL, Choi H, Porter NA, Jeong BS. Pyridoxine-derived bicyclic aminopyridinol antioxidants: synthesis and their antioxidant activities. Organic & Biomolecular Chemistry. 9: 8475-82. PMID 22042081 DOI: 10.1039/C1Ob05144J  0.75
2011 Nam TG, Ku JM, Park HG, Porter NA, Jeong BS. New synthetic route to N-tocopherol derivatives: synthesis of pyrrolopyridinol analogue of α-tocopherol from pyridoxine. Organic & Biomolecular Chemistry. 9: 1749-55. PMID 21253656 DOI: 10.1039/C0Ob00991A  0.535
2010 Serwa R, Nam TG, Valgimigli L, Culbertson S, Rector CL, Jeong BS, Pratt DA, Porter NA. Preparation and investigation of vitamin B6-derived aminopyridinol antioxidants. Chemistry (Weinheim An Der Bergstrasse, Germany). 16: 14106-14. PMID 20967898 DOI: 10.1002/Chem.201001382  0.607
2010 Omata Y, Saito Y, Yoshida Y, Jeong BS, Serwa R, Nam TG, Porter NA, Niki E. Action of 6-amino-3-pyridinols as novel antioxidants against free radicals and oxidative stress in solution, plasma, and cultured cells. Free Radical Biology & Medicine. 48: 1358-65. PMID 20172025 DOI: 10.1016/J.Freeradbiomed.2010.02.018  0.746
2009 Nam TG, Nara SJ, Zagol-Ikapitte I, Cooper T, Valgimigli L, Oates JA, Porter NA, Boutaud O, Pratt DA. Pyridine and pyrimidine analogs of acetaminophen as inhibitors of lipid peroxidation and cyclooxygenase and lipoxygenase catalysis. Organic & Biomolecular Chemistry. 7: 5103-12. PMID 20024105 DOI: 10.1039/B912528K  0.694
2008 Plouffe D, Brinker A, McNamara C, Henson K, Kato N, Kuhen K, Nagle A, Adrián F, Matzen JT, Anderson P, Nam TG, Gray NS, Chatterjee A, Janes J, Yan SF, et al. In silico activity profiling reveals the mechanism of action of antimalarials discovered in a high-throughput screen. Proceedings of the National Academy of Sciences of the United States of America. 105: 9059-64. PMID 18579783 DOI: 10.1073/Pnas.0802982105  0.314
2007 Nam TG, Rector CL, Kim HY, Sonnen AF, Meyer R, Nau WM, Atkinson J, Rintoul J, Pratt DA, Porter NA. Tetrahydro-1,8-naphthyridinol analogues of alpha-tocopherol as antioxidants in lipid membranes and low-density lipoproteins. Journal of the American Chemical Society. 129: 10211-9. PMID 17655300 DOI: 10.1021/Ja072371M  0.705
2005 Nam T, Wijtmans M, Pratt DA, Porter NA. Regioselective addition of n-alkyllithiums to alpha,alpha '-disubstituted-1,8-naphthyridines: Synthesis of 6-amino-3-pyridinol analogs of alpha-tocopherol Synthesis. 2005: 1397-1404. DOI: 10.1055/S-2005-865308  0.655
2005 Nam TG, Wijtmans M, Pratt DA, Porter NA. Regioselective addition of n-alkyllithiums to α,α′- disubstituted-1,8-naphthyridines: Synthesis of 6-amino-3-pyridinol analogs of α-tocopherol Synthesis. 1397-1404. DOI: 10.1002/CHIN.200541153  0.593
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