Year |
Citation |
Score |
2023 |
Ahanin EF, Sager RA, Backe SJ, Dunn DM, Dushukyan N, Blanden AR, Mate NA, Suzuki T, Anderson T, Roy M, Oberoi J, Prodromou C, Nsouli I, Daneshvar M, Bratslavsky G, ... ... Chisholm JD, et al. Catalytic inhibitor of Protein Phosphatase 5 activates the extrinsic apoptotic pathway by disrupting complex II in kidney cancer. Cell Chemical Biology. PMID 37527661 DOI: 10.1016/j.chembiol.2023.06.026 |
0.769 |
|
2023 |
Fernandes S, Srivastava N, Pedicone C, Sudan R, Luke EA, Dungan OM, Pacherille A, Meyer ST, Dormann S, Schurmans S, Chambers BJ, Chisholm JD, Kerr WG. Obesity control by SHIP inhibition requires pan-paralog inhibition and an intact eosinophil compartment. Iscience. 26: 106071. PMID 36818285 DOI: 10.1016/j.isci.2023.106071 |
0.752 |
|
2022 |
Fernandes S, Meyer ST, Shah JP, Adhikari AA, Kerr WG, Chisholm JD. -Benzyl Tryptamine Pan-SHIP1/2 Inhibitors: Synthesis and Preliminary Biological Evaluation as Anti-Tumor Agents. Molecules (Basel, Switzerland). 27. PMID 36500543 DOI: 10.3390/molecules27238451 |
0.76 |
|
2022 |
Dungan OM, Dormann S, Fernandes S, Duffy BC, Effiong DG, Kerr WG, Chisholm JD. Synthetic studies on the indane SHIP1 agonist AQX-1125. Organic & Biomolecular Chemistry. PMID 35506893 DOI: 10.1039/d2ob00555g |
0.763 |
|
2022 |
Mate NA, Meador RIL, Joshi BD, Chisholm JD. Alkylation of isatins with trichloroacetimidates. Organic & Biomolecular Chemistry. PMID 35229852 DOI: 10.1039/d2ob00127f |
0.348 |
|
2020 |
Kerr WG, Pedicone C, Dormann S, Pacherille A, Chisholm JD. Small molecule targeting of SHIP1 and SHIP2. Biochemical Society Transactions. PMID 32049315 DOI: 10.1042/Bst20190775 |
0.301 |
|
2019 |
Pedicone C, Fernandes S, Dungan OM, Dormann SM, Viernes DR, Adhikari AA, Choi LB, De Jong EP, Chisholm JD, Kerr WG. Pan-SHIP1/2 inhibitors promote microglia effector functions essential for CNS homeostasis. Journal of Cell Science. PMID 31780579 DOI: 10.1242/Jcs.238030 |
0.75 |
|
2019 |
Suzuki T, Mate NA, Adhikari AA, Chisholm JD. Dialkylation of Indoles with Trichloroacetimidates to Access 3,3-Disubstituted Indolenines. Molecules (Basel, Switzerland). 24. PMID 31731742 DOI: 10.3390/Molecules24224143 |
0.791 |
|
2019 |
Suzuki T, Chisholm JD. Friedel-Crafts Alkylation of Indoles with Trichloroacetimidates. Tetrahedron Letters. 60: 1325-1329. PMID 31481819 DOI: 10.1016/J.Tetlet.2019.04.007 |
0.812 |
|
2019 |
Mahajani NS, Meador RIL, Smith TJ, Canarelli SE, Adhikari AA, Shah JP, Russo CM, Wallach DR, Howard KT, Millimaci AM, Chisholm JD. Ester Formation via Symbiotic Activation Utilizing Trichloroacetimidate Electrophiles. The Journal of Organic Chemistry. PMID 31117564 DOI: 10.1021/Acs.Joc.9B00745 |
0.758 |
|
2018 |
Saz-Leal P, Del Fresno C, Brandi P, Martínez-Cano S, Dungan OM, Chisholm JD, Kerr WG, Sancho D. Targeting SHIP-1 in Myeloid Cells Enhances Trained Immunity and Boosts Response to Infection. Cell Reports. 25: 1118-1126. PMID 30380404 DOI: 10.1016/J.Celrep.2018.09.092 |
0.744 |
|
2018 |
Mahajani NS, Chisholm JD. Promoter free allylation of trichloroacetimidates with allyltributylstannanes under thermal conditions to access the common 1,1'-diarylbutyl pharmacophore. Organic & Biomolecular Chemistry. PMID 29766199 DOI: 10.1039/C8Ob00687C |
0.804 |
|
2018 |
Mahajani NS, Chisholm JD. Synthesis of 1,1'-Diarylethanes and Related Systems by Displacement of Trichloroacetimidates with Trimethylaluminum. The Journal of Organic Chemistry. PMID 29478311 DOI: 10.1021/Acs.Joc.8B00027 |
0.793 |
|
2018 |
Wilhelmsen CA, Dixon ADC, Chisholm JD, Clark DA. Synthesis of N-Substituted-3-amino-4-halopyridines: a Sequential Boc-Removal/Reductive Amination Mediated by Brønsted and Lewis Acids. The Journal of Organic Chemistry. PMID 29308898 DOI: 10.1021/Acs.Joc.7B02966 |
0.803 |
|
2018 |
Dolan MA, Dixon AD, Chisholm JD, Clark DA. Ruthenium dihydride complexes as enyne metathesis catalysts Tetrahedron Letters. 59: 4471-4474. DOI: 10.1016/J.Tetlet.2018.11.016 |
0.372 |
|
2017 |
Adhikari AA, Radal L, Chisholm JD. Synthesis of 3,3'-Disubstituted Indolenines Utilizing the Lewis Acid Catalyzed Alkylation of 2,3-Disubstituted Indoles with Trichloroacetimidates. Synlett : Accounts and Rapid Communications in Synthetic Organic Chemistry. 28: 2335-2339. PMID 29033500 DOI: 10.1055/S-0036-1588491 |
0.802 |
|
2017 |
Adhikari AA, Suzuki T, Gilbert RJ, Linaburg MR, Chisholm JD. Rearrangement of Benzylic Trichloroacetimidates to Benzylic Trichloroacetamides. The Journal of Organic Chemistry. PMID 28323428 DOI: 10.1021/Acs.Joc.7B00245 |
0.784 |
|
2017 |
McGovern-Gooch KR, Mahajani NS, Garagozzo A, Schramm AJ, Hannah LG, Sieburg MA, Chisholm JD, Hougland JL. Synthetic triterpenoid inhibition of human ghrelin O-acyltransferase: Involvement of a functionally required cysteine provides mechanistic insight into ghrelin acylation. Biochemistry. PMID 28134508 DOI: 10.1021/Acs.Biochem.6B01008 |
0.776 |
|
2016 |
Hoekstra E, Das AM, Willemsen M, Swets M, Kuppen PJ, van der Woude CJ, Bruno MJ, Shah JP, Ten Hagen TL, Chisholm JD, Kerr WG, Peppelenbosch MP, Fuhler GM. Lipid phosphatase SHIP2 functions as oncogene in colorectal cancer by regulating PKB activation. Oncotarget. PMID 27716613 DOI: 10.18632/Oncotarget.12321 |
0.758 |
|
2016 |
Howard KT, Chisholm JD. Preparation and Applications of 4-Methoxybenzyl Esters in Organic Synthesis. Organic Preparations and Procedures International. 48: 1-36. PMID 27546912 DOI: 10.1080/00304948.2016.1127096 |
0.759 |
|
2016 |
Srivastava N, Iyer S, Sudan R, Youngs C, Engelman RW, Howard KT, Russo CM, Chisholm JD, Kerr WG. A small-molecule inhibitor of SHIP1 reverses age- and diet-associated obesity and metabolic syndrome. Jci Insight. 1. PMID 27536730 DOI: 10.1172/Jci.Insight.88544 |
0.736 |
|
2016 |
Wallach DR, Chisholm JD. Alkylation of Sulfonamides with Trichloroacetimidates under Thermal Conditions. The Journal of Organic Chemistry. PMID 27487402 DOI: 10.1021/Acs.Joc.6B01421 |
0.738 |
|
2016 |
Adhikari AA, Chisholm JD. Lewis Acid Catalyzed Displacement of Trichloroacetimidates in the Synthesis of Functionalized Pyrroloindolines. Organic Letters. PMID 27486831 DOI: 10.1021/Acs.Orglett.6B02024 |
0.768 |
|
2016 |
Howard KT, Chisholm JD. Preparation and Applications of 4-Methoxybenzyl Esters in Organic Synthesis Organic Preparations and Procedures International. 48: 1-36. DOI: 10.1080/00304948.2016.1127096 |
0.746 |
|
2015 |
Howard KT, Duffy BC, Linaburg MR, Chisholm JD. Formation of DPM ethers using O-diphenylmethyl trichloroacetimidate under thermal conditions. Organic & Biomolecular Chemistry. PMID 26691695 DOI: 10.1039/C5Ob02455B |
0.802 |
|
2015 |
Russo CM, Adhikari AA, Wallach DR, Fernandes S, Balch AN, Kerr WG, Chisholm JD. Synthesis and initial evaluation of quinoline-based inhibitors of the SH2-containing inositol 5'-phosphatase (SHIP). Bioorganic & Medicinal Chemistry Letters. 25: 5344-8. PMID 26453006 DOI: 10.1016/J.Bmcl.2015.09.034 |
0.791 |
|
2015 |
Fernandes S, Brooks R, Gumbleton M, Park MY, Russo CM, Howard KT, Chisholm JD, Kerr WG. SHIPi Enhances Autologous and Allogeneic Hematolymphoid Stem Cell Transplantation. Ebiomedicine. 2: 205-213. PMID 26052545 DOI: 10.1016/J.Ebiom.2015.02.004 |
0.73 |
|
2015 |
Wallach DR, Stege PC, Shah JP, Chisholm JD. Brønsted acid catalyzed monoalkylation of anilines with trichloroacetimidates. The Journal of Organic Chemistry. 80: 1993-2000. PMID 25568933 DOI: 10.1021/Jo5027222 |
0.806 |
|
2015 |
Corcoran JT, Carberry P, Viernes DR, Chisholm JD. Intramolecular diels-alder reactions utilizing aldehyde and ketone dienophiles, a rare cycloaddition reaction Mini-Reviews in Organic Chemistry. 12: 149-161. DOI: 10.2174/1570193X11666141029000030 |
0.624 |
|
2015 |
Duffy BC, Howard KT, Chisholm JD. Alkylation of thiols with trichloroacetimidates under neutral conditions Tetrahedron Letters. 56: 3301-3305. DOI: 10.1016/J.Tetlet.2014.12.042 |
0.799 |
|
2014 |
Adhikari AA, Shah JP, Howard KT, Russo CM, Wallach DR, Linaburg MR, Chisholm JD. Convenient Formation of Diphenylmethyl Esters Using Diphenylmethyl Trichloroacetimidate Synlett. 25: 283-287. DOI: 10.1055/S-0033-1340293 |
0.776 |
|
2014 |
Shah JP, Russo CM, Howard KT, Chisholm JD. Spontaneous formation of PMB esters using 4-methoxybenzyl-2,2,2- trichloroacetimidate Tetrahedron Letters. 55: 1740-1742. DOI: 10.1016/J.Tetlet.2014.01.097 |
0.795 |
|
2013 |
Carberry P, Viernes DR, Choi LB, Fegley MW, Chisholm JD. An unusual intramolecular Diels-Alder approach toward maoecrystal v Tetrahedron Letters. 54: 1734-1737. DOI: 10.1016/J.Tetlet.2013.01.075 |
0.653 |
|
2013 |
Lerum RV, Russo CM, Marquez JE, Chisholm JD. A rhodium-catalyzed tandem alkyne dimerization/1,4-addition reaction Advanced Synthesis and Catalysis. 355: 3485-3491. DOI: 10.1002/Adsc.201300743 |
0.353 |
|
2007 |
Dhondi PK, Carberry P, Choi LB, Chisholm JD. Addition of alkynes to aldehydes and activated ketones catalyzed by rhodium-phosphine complexes. The Journal of Organic Chemistry. 72: 9590-6. PMID 17999525 DOI: 10.1021/Jo701643H |
0.669 |
|
2007 |
Yin J, Gallis CE, Chisholm JD. Tandem oxidation/halogenation of aryl allylic alcohols under Moffatt-Swern conditions. The Journal of Organic Chemistry. 72: 7054-7. PMID 17685577 DOI: 10.1021/Jo0711992 |
0.36 |
|
2007 |
Dhondi PK, Carberry P, Chisholm JD. Ligand effects in the rhodium-catalyzed addition of alkynes to aldehydes and diketones. Modification of the β-diketonate ligand Tetrahedron Letters. 48: 8743-8746. DOI: 10.1016/J.Tetlet.2007.10.010 |
0.636 |
|
2007 |
Ganci GR, Chisholm JD. Rhodium-catalyzed addition of aryl boronic acids to 1,2-diketones and 1,2-ketoesters Tetrahedron Letters. 48: 8266-8269. DOI: 10.1016/J.Tetlet.2007.09.137 |
0.445 |
|
2006 |
Zhang C, Albermann C, Fu X, Peters NR, Chisholm JD, Zhang G, Gilbert EJ, Wang PG, Van Vranken DL, Thorson JS. RebG- and RebM-catalyzed indolocarbazole diversification. Chembiochem : a European Journal of Chemical Biology. 7: 795-804. PMID 16575939 DOI: 10.1002/Cbic.200500504 |
0.76 |
|
2006 |
Yin J, Chisholm JD. Palladium-catalyzed addition of alkynes to cyclopropenes. Chemical Communications (Cambridge, England). 632-4. PMID 16446833 DOI: 10.1039/B516021A |
0.426 |
|
2006 |
Dhondi PK, Chisholm JD. Rhodium-catalyzed addition of alkynes to activated ketones and aldehydes. Organic Letters. 8: 67-9. PMID 16381569 DOI: 10.1021/Ol0525260 |
0.456 |
|
2006 |
Weeden JA, Chisholm JD. Phosphine-catalyzed nitroaldol reactions Tetrahedron Letters. 47: 9313-9316. DOI: 10.1016/J.Tetlet.2006.10.107 |
0.357 |
|
2006 |
Trost BM, Harrington PE, Chisholm JD, Wrobleski ST. Total Synthesis of (+)-Amphidinolide A. Structural Elucidation and Completion of the Synthesis. Cheminform. 37. DOI: 10.1002/chin.200606218 |
0.456 |
|
2006 |
Trost BM, Wrobleski ST, Chisholm JD, Harrington PE, Jung M. Total Synthesis of (+)-Amphidinolide A. Assembly of the Fragments. Cheminform. 37. DOI: 10.1002/chin.200606217 |
0.43 |
|
2005 |
Trost BM, Harrington PE, Chisholm JD, Wrobleski ST. Total synthesis of (+)-amphidinolide A. Structure elucidation and completion of the synthesis. Journal of the American Chemical Society. 127: 13598-610. PMID 16190725 DOI: 10.1021/Ja053365Y |
0.524 |
|
2005 |
Trost BM, Wrobleski ST, Chisholm JD, Harrington PE, Jung M. Total synthesis of (+)-amphidinolide A. Assembly of the fragments. Journal of the American Chemical Society. 127: 13589-97. PMID 16190724 DOI: 10.1021/Ja0533646 |
0.551 |
|
2004 |
Lerum RV, Chisholm JD. Rhodium-catalyzed 1,4-addition of terminal alkynes to vinyl ketones Tetrahedron Letters. 45: 6591-6594. DOI: 10.1016/J.Tetlet.2004.07.036 |
0.406 |
|
2003 |
Facompré M, Carrasco C, Vezin H, Chisholm JD, Yoburn JC, Van Vranken DL, Bailly C. Indolocarbazole glycosides in inactive conformations. Chembiochem : a European Journal of Chemical Biology. 4: 386-95. PMID 12740810 DOI: 10.1002/Cbic.200200478 |
0.764 |
|
2003 |
Trost BM, Chisholm JD. An Acid-Catalyzed Macrolactonization Protocol. Cheminform. 34. DOI: 10.1002/chin.200310073 |
0.49 |
|
2003 |
Trost BM, Chisholm JD, Wrobleski ST, Jung M. Ruthenium-Catalyzed Alkene—Alkyne Coupling: Synthesis of the Proposed Structure of Amphidinolide A. Cheminform. 34. DOI: 10.1002/chin.200307173 |
0.436 |
|
2002 |
Facompre M, Carrasco C, Colson P, Houssier C, Chisholm JD, Van Vranken DL, Bailly C. DNA binding and topoisomerase I poisoning activities of novel disaccharide indolocarbazoles. Molecular Pharmacology. 62: 1215-27. PMID 12391286 DOI: 10.1124/Mol.62.5.1215 |
0.741 |
|
2002 |
Trost BM, Chisholm JD, Wrobleski ST, Jung M. Ruthenium-catalyzed alkene-alkyne coupling: synthesis of the proposed structure of amphidinolide A. Journal of the American Chemical Society. 124: 12420-1. PMID 12381177 DOI: 10.1021/Ja027883+ |
0.543 |
|
2002 |
Trost BM, Chisholm JD. An acid-catalyzed macrolactonization protocol. Organic Letters. 4: 3743-5. PMID 12375933 DOI: 10.1021/Ol026726C |
0.585 |
|
2002 |
Carrasco C, Facompré M, Chisholm JD, Van Vranken DL, Wilson WD, Bailly C. DNA sequence recognition by the indolocarbazole antitumor antibiotic AT2433-B1 and its diastereoisomer. Nucleic Acids Research. 30: 1774-81. PMID 11937631 DOI: 10.1093/Nar/30.8.1774 |
0.734 |
|
2000 |
Chisholm JD, Van Vranken DL. Regiocontrolled synthesis of the antitumor antibiotic AT2433-A1. The Journal of Organic Chemistry. 65: 7541-53. PMID 11076613 DOI: 10.1021/Jo000911R |
0.764 |
|
1999 |
Gilbert EJ, Chisholm JD, Van Vranken DL. Conformational Control in the Rebeccamycin Class of Indolocarbazole Glycosides. The Journal of Organic Chemistry. 64: 5670-5676. PMID 11674638 DOI: 10.1021/Jo990296V |
0.721 |
|
1999 |
Chisholm JD, Golik J, Krishnan B, Matson JA, Van Vranken DL. A caveat in the application of the exciton chirality method to N,N- dialkyl amides. Synthesis and structural revision of AT2433-B1 [12] Journal of the American Chemical Society. 121: 3801-3802. DOI: 10.1021/Ja9842924 |
0.749 |
|
1995 |
Chisholm JD, Van Vranken DL. Glycosylation of 2,2'-indolylindolines Journal of Organic Chemistry. 60: 6672-6673. DOI: 10.1021/Jo00126A011 |
0.719 |
|
Show low-probability matches. |