Raymond Hupperts - Publications

Affiliations: 
2007-2011 Neurology Maastricht University Medical Center+ 

137 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2022 Giovannoni G, Popescu V, Wuerfel J, Hellwig K, Iacobeus E, Jensen MB, García-Domínguez JM, Sousa L, De Rossi N, Hupperts R, Fenu G, Bodini B, Kuusisto HM, Stankoff B, Lycke J, et al. Smouldering multiple sclerosis: the 'real MS'. Therapeutic Advances in Neurological Disorders. 15: 17562864211066751. PMID 35096143 DOI: 10.1177/17562864211066751  0.364
2021 Mimpen M, Rolf L, Poelmans G, van den Ouweland J, Hupperts R, Damoiseaux J, Smolders J. Vitamin D related genetic polymorphisms affect serological response to high-dose vitamin D supplementation in multiple sclerosis. Plos One. 16: e0261097. PMID 34855907 DOI: 10.1371/journal.pone.0261097  0.7
2021 Mimpen M, Damoiseaux J, van Doorn W, Rolf L, Muris AH, Hupperts R, van Luijn MM, Gerlach O, Smolders J. Proportions of circulating transitional B cells associate with MRI activity in interferon beta-treated multiple sclerosis patients. Journal of Neuroimmunology. 358: 577664. PMID 34280843 DOI: 10.1016/j.jneuroim.2021.577664  0.63
2021 Mimpen M, Damoiseaux J, van Doorn W, Rolf L, Muris AH, Hupperts R, van Luijn MM, Gerlach O, Smolders J. Proportions of circulating transitional B cells associate with MRI activity in interferon beta-treated multiple sclerosis patients. Journal of Neuroimmunology. 358: 577664. PMID 34280843 DOI: 10.1016/j.jneuroim.2021.577664  0.63
2021 Boltjes R, Knippenberg S, Gerlach O, Hupperts R, Damoiseaux J. Vitamin D supplementation in multiple sclerosis: an expert opinion based on the review of current evidence. Expert Review of Neurotherapeutics. 21: 715-725. PMID 34058936 DOI: 10.1080/14737175.2021.1935878  0.513
2021 Mimpen M, Rolf L, Muris AH, Gerlach O, Poelmans G, Hupperts R, Smolders J, Damoiseaux J. NK/T cell ratios associate with interleukin-2 receptor alpha chain expression and shedding in multiple sclerosis. Journal of Neuroimmunology. 353: 577499. PMID 33529846 DOI: 10.1016/j.jneuroim.2021.577499  0.565
2020 Mimpen M, Muris AH, Rolf L, Gerlach O, Kuhle J, Hupperts R, Smolders J, Damoiseaux J. Prognostic value of NK cell/ T cell ratios for disease activity in multiple sclerosis. European Journal of Neurology. PMID 33326677 DOI: 10.1111/ene.14680  0.615
2020 Roos I, Leray E, Frascoli F, Casey R, Brown JWL, Horakova D, Havrdova EK, Trojano M, Patti F, Izquierdo G, Eichau S, Onofrj M, Lugaresi A, Prat A, Girard M, ... ... Hupperts R, et al. Delay from treatment start to full effect of immunotherapies for multiple sclerosis. Brain : a Journal of Neurology. 143: 2742-2756. PMID 32947619 DOI: 10.1093/Brain/Awaa231  0.358
2020 Lizak N, Malpas CB, Sharmin S, Havrdova EK, Horakova D, Izquierdo G, Eichau S, Lugaresi A, Duquette P, Girard M, Prat A, Larochelle C, Trojano M, Grand'Maison F, Grammond P, ... ... Hupperts R, et al. Association of Sustained Immunotherapy With Disability Outcomes in Patients With Active Secondary Progressive Multiple Sclerosis. Jama Neurology. PMID 32716480 DOI: 10.1001/Jamaneurol.2020.2453  0.415
2020 Kunchok A, Lechner-Scott J, Granella F, Trojano M, Alroughani R, Sola P, Ferraro D, Lugaresi A, Onofrj M, Ozakbas S, Izquierdo G, Grammond P, Luis Sanchez-Menoyo J, Van Wijmeersch B, Boz C, ... ... Hupperts R, et al. Prediction of on-treatment disability worsening in RRMS with the MAGNIMS score. Multiple Sclerosis (Houndmills, Basingstoke, England). 1352458520936823. PMID 32639855 DOI: 10.1177/1352458520936823  0.304
2020 Le M, Malpas C, Sharmin S, Horáková D, Havrdova E, Trojano M, Izquierdo G, Eichau S, Ozakbas S, Lugaresi A, Prat A, Girard M, Duquette P, Larochelle C, Alroughani R, ... ... Hupperts R, et al. Disability outcomes of early cerebellar and brainstem symptoms in multiple sclerosis. Multiple Sclerosis (Houndmills, Basingstoke, England). 1352458520926955. PMID 32538713 DOI: 10.1177/1352458520926955  0.387
2020 Malpas CB, Manouchehrinia A, Sharmin S, Roos I, Horakova D, Havrdova EK, Trojano M, Izquierdo G, Eichau S, Bergamaschi R, Sola P, Ferraro D, Lugaresi A, Prat A, Girard M, ... ... Hupperts R, et al. Early clinical markers of aggressive multiple sclerosis. Brain : a Journal of Neurology. PMID 32386427 DOI: 10.1093/Brain/Awaa081  0.392
2020 He A, Merkel B, Brown JWL, Zhovits Ryerson L, Kister I, Malpas CB, Sharmin S, Horakova D, Kubala Havrdova E, Spelman T, Izquierdo G, Eichau S, Trojano M, Lugaresi A, Hupperts R, et al. Timing of high-efficacy therapy for multiple sclerosis: a retrospective observational cohort study. The Lancet. Neurology. 19: 307-316. PMID 32199096 DOI: 10.1016/S1474-4422(20)30067-3  0.32
2020 Mimpen M, Smolders J, Hupperts R, Damoiseaux J. Natural killer cells in multiple sclerosis: A review. Immunology Letters. 222: 1-11. PMID 32113900 DOI: 10.1016/J.Imlet.2020.02.012  0.66
2019 Smolders J, Damoiseaux J, Hupperts R. Hypercalcaemia rather than high dose vitamin D3 supplements could exacerbate multiple sclerosis. Brain : a Journal of Neurology. PMID 31665228 DOI: 10.1093/Brain/Awz339  0.7
2019 Smolders J, Mimpen M, Oechtering J, Damoiseaux J, van den Ouweland J, Hupperts R, Kuhle J. Vitamin D supplementation and neurofilament light chain in multiple sclerosis. Acta Neurologica Scandinavica. PMID 31657006 DOI: 10.1111/Ane.13185  0.697
2019 Hupperts R, Smolders J, Vieth R, Holmøy T, Marhardt K, Schluep M, Killestein J, Barkhof F, Beelke M, Grimaldi LME. Randomized trial of daily high-dose vitamin D in patients with RRMS receiving subcutaneous interferon β-1a. Neurology. PMID 31594857 DOI: 10.1212/Wnl.0000000000008445  0.667
2019 Fambiatos A, Jokubaitis V, Horakova D, Kubala Havrdova E, Trojano M, Prat A, Girard M, Duquette P, Lugaresi A, Izquierdo G, Grand'Maison F, Grammond P, Sola P, Ferraro D, Alroughani R, ... ... Hupperts R, et al. Risk of secondary progressive multiple sclerosis: A longitudinal study. Multiple Sclerosis (Houndmills, Basingstoke, England). 1352458519868990. PMID 31397221 DOI: 10.1177/1352458519868990  0.374
2019 Cadavid D, Mellion M, Hupperts R, Edwards KR, Calabresi PA, Drulović J, Giovannoni G, Hartung HP, Arnold DL, Fisher E, Rudick R, Mi S, Chai Y, Li J, Zhang Y, et al. Safety and efficacy of opicinumab in patients with relapsing multiple sclerosis (SYNERGY): a randomised, placebo-controlled, phase 2 trial. The Lancet. Neurology. PMID 31285147 DOI: 10.1016/S1474-4422(19)30137-1  0.358
2019 Cambron M, Mostert J, D'Hooghe M, Nagels G, Willekens B, Debruyne J, Algoed L, Verhagen W, Hupperts R, Heersema D, De Keyser J. Fluoxetine in progressive multiple sclerosis: The FLUOX-PMS trial. Multiple Sclerosis (Houndmills, Basingstoke, England). 1352458519843051. PMID 31218911 DOI: 10.1177/1352458519843051  0.425
2019 Brown JWL, Coles A, Horakova D, Havrdova E, Izquierdo G, Prat A, Girard M, Duquette P, Trojano M, Lugaresi A, Bergamaschi R, Grammond P, Alroughani R, Hupperts R, McCombe P, et al. Association of Initial Disease-Modifying Therapy With Later Conversion to Secondary Progressive Multiple Sclerosis. Jama. 321: 175-187. PMID 30644981 DOI: 10.1001/Jama.2018.20588  0.473
2019 Hupperts R, Hobart J, Gasperini C, Lycke J, Ziemssen T, Feys P, McNeill M, Acosta C. 191 MOBILE/ENHANCE integrated efficacy analysis of PR-fampridine Journal of Neurology, Neurosurgery, and Psychiatry. 90. DOI: 10.1136/Jnnp-2019-Abn-2.163  0.313
2018 Rolf L, Smolders J, van den Ouweland J, Hupperts R, Damoiseaux J. Correlation of different cellular assays to analyze T cell-related cytokine profiles in vitamin D-supplemented patients with multiple sclerosis. Molecular Immunology. 105: 198-204. PMID 30550982 DOI: 10.1016/J.Molimm.2018.12.001  0.655
2018 Hobart J, Ziemssen T, Feys P, Linnebank M, Goodman AD, Farrell R, Hupperts R, Blight AR, Englishby V, McNeill M, Chang I, Lima G, Elkins J. Assessment of Clinically Meaningful Improvements in Self-Reported Walking Ability in Participants with Multiple Sclerosis: Results from the Randomized, Double-Blind, Phase III ENHANCE Trial of Prolonged-Release Fampridine. Cns Drugs. PMID 30535670 DOI: 10.1007/S40263-018-0586-5  0.427
2018 Diaz GM, Hupperts R, Fraussen J, Somers V. Dimethyl fumarate treatment in multiple sclerosis: Recent advances in clinical and immunological studies. Autoimmunity Reviews. PMID 30316988 DOI: 10.1016/J.Autrev.2018.07.001  0.455
2018 Albrecht P, Bjørnå IK, Brassat D, Farrell R, Feys P, Hobart J, Hupperts R, Linnebank M, Magdič J, Oreja-Guevara C, Pozzilli C, Salgado AV, Ziemssen T. Prolonged-release fampridine in multiple sclerosis: clinical data and real-world experience. Report of an expert meeting. Therapeutic Advances in Neurological Disorders. 11: 1756286418803248. PMID 30305850 DOI: 10.1177/1756286418803248  0.449
2018 Lorscheider J, Kuhle J, Izquierdo G, Lugaresi A, Havrdova E, Horakova D, Hupperts R, Duquette P, Girard M, Prat A, Grand'Maison F, Grammond P, Sola P, Ferraro D, Trojano M, et al. Anti-inflammatory disease modifying treatment and disability progression in primary progressive multiple sclerosis: a cohort study. European Journal of Neurology. PMID 30298572 DOI: 10.1111/Ene.13824  0.355
2018 Min M, Spelman T, Lugaresi A, Boz C, Spitaleri D, Pucci E, Grand'Maison F, Granella F, Izquierdo G, Butzkueven H, Sanchez-Menoyo JL, Barnett M, Girard M, Trojano M, Grammond P, ... ... Hupperts R, et al. Silent lesions on MRI imaging - Shifting goal posts for treatment decisions in multiple sclerosis. Multiple Sclerosis (Houndmills, Basingstoke, England). 1352458518798147. PMID 30234431 DOI: 10.1177/1352458518798147  0.37
2018 Kister I, Spelman T, Patti F, Duquette P, Trojano M, Izquierdo G, Lugaresi A, Grammond P, Sola P, Ferraro D, Grand'Maison F, Alroughani R, Terzi M, Boz C, Hupperts R, et al. Predictors of relapse and disability progression in MS patients who discontinue disease-modifying therapy. Journal of the Neurological Sciences. 391: 72-76. PMID 30103975 DOI: 10.1016/J.Jns.2018.06.001  0.439
2018 Hughes J, Jokubaitis V, Lugaresi A, Hupperts R, Izquierdo G, Prat A, Girard M, Duquette P, Grand'Maison F, Grammond P, Sola P, Ferraro D, Ramo-Tello C, Trojano M, Slee M, et al. Association of Inflammation and Disability Accrual in Patients With Progressive-Onset Multiple Sclerosis. Jama Neurology. PMID 30083762 DOI: 10.1001/Jamaneurol.2018.2109  0.468
2018 Diaz GM, Fraussen J, Wijmeersch BV, Hupperts R, Somers V. Dimethyl fumarate induces a persistent change in the composition of the innate and adaptive immune system in multiple sclerosis patients. Scientific Reports. 8: 8194. PMID 29844361 DOI: 10.1038/S41598-018-26519-W  0.448
2018 Rolf L, Damoiseaux J, Huitinga I, Kimenai D, van den Ouweland J, Hupperts R, Smolders J. Stress-Axis Regulation by Vitamin D in Multiple Sclerosis. Frontiers in Neurology. 9: 263. PMID 29755397 DOI: 10.3389/Fneur.2018.00263  0.716
2018 Schippling S, Langdon D, Solari A, Brochet B, Hupperts R, Piehl F, Lechner-Scott J, Montalban X, Keller B, Alexandri N. THUR 172 Phase iv study of cladribine tablets and quality of life: clarify-ms Journal of Neurology, Neurosurgery, and Psychiatry. 89. DOI: 10.1136/Jnnp-2018-Abn.79  0.344
2018 Jhuti G, Freitas R, Bennett I, Butzkueven H, Izquierdo G, Eichau S, Havrdova E, Horakova D, Duquette P, Prat A, Girard M, Grand'Maison F, Hupperts R, Lugaresi A, Onofrj M, et al. PND18 - PROGRESSION OF DISABILITY IN PRIMARY PROGRESSIVE MULTIPLE SCLEROSIS: A RETROSPECTIVE COHORT STUDY USING DATA FROM THE MSBASE REGISTRY AND A CONTEXTUALISATION WITH AN EXISTING NATURAL HISTORY DATASET Value in Health. 21: S332. DOI: 10.1016/J.Jval.2018.09.1985  0.372
2017 Rolf L, Muris AH, Theunissen R, Hupperts R, Damoiseaux J, Smolders J. Vitamin D3 supplementation and the IL-2/IL-2R pathway in multiple sclerosis: Attenuation of progressive disturbances? Journal of Neuroimmunology. PMID 29153546 DOI: 10.1016/J.Jneuroim.2017.11.007  0.683
2017 Brown JWL, Lugaresi A, Horakova D, Havrdova E, Jokubaitis V, Lechner-Scott J, Trojano M, Min M, Shaw C, Shuey N, Slee M, Mccombe P, Pesch VV, Wijmeersch BV, Prevost J, ... ... Hupperts R, et al. The risk of relapse following on-treatment clinically silent lesions in patients with relapsing-remitting multiple sclerosis Multiple Sclerosis Journal. 23: 992-994. PMID 29065759 DOI: 10.1177/1352458517733228  0.367
2017 Jokubaitis VG, Havrdova E, Horakova D, Izquierdo G, Kalincik T, Walt Avd, Nguyen AL, Terzi M, Alroughani R, Duquette P, Girard M, Prat A, Boz C, Sola P, Lugaresi A, ... ... Hupperts R, et al. Pregnancy incidence and therapy exposure in relapsing forms of MS: a 12-year retrospective multicentre analysis Multiple Sclerosis Journal. 23: 130-132. PMID 29065758 DOI: 10.1177/1352458517731404  0.363
2017 Kalincik T, Manouchehrinia A, Sobisek L, Jokubaitis V, Spelman T, Horakova D, Havrdova E, Trojano M, Izquierdo G, Lugaresi A, Girard M, Prat A, Duquette P, Grammond P, Sola P, ... Hupperts R, et al. Towards personalized therapy for multiple sclerosis: prediction of individual treatment response. Brain : a Journal of Neurology. 140: 2426-2443. PMID 29050389 DOI: 10.1093/Brain/Awx185  0.341
2017 Rolf L, Muris AH, Mathias A, Du Pasquier R, Koneczny I, Disanto G, Kuhle J, Ramagopalan S, Damoiseaux J, Smolders J, Hupperts R. Exploring the effect of vitamin D3 supplementation on the anti-EBV antibody response in relapsing-remitting multiple sclerosis. Multiple Sclerosis (Houndmills, Basingstoke, England). 1352458517722646. PMID 28731372 DOI: 10.1177/1352458517722646  0.717
2017 Smolders J, Rolf L, Damoiseaux J, Hupperts R. On the ethics of not supplementing low 25-hydroxyvitamin D levels in a controlled study in relapsing remitting multiple sclerosis. Journal of the Neurological Sciences. PMID 28629873 DOI: 10.1016/J.Jns.2017.06.009  0.701
2017 Hoogerwerf AEW, Bol Y, Lobbestael J, Hupperts R, van Heugten CM. Mindfulness-based cognitive therapy severely fatigued multiple sclerosis patients: A waiting list controlled study. Journal of Rehabilitation Medicine. PMID 28597907 DOI: 10.2340/16501977-2237  0.361
2017 Rolf L, Muris AH, Bol Y, Damoiseaux J, Smolders J, Hupperts R. Vitamin D3 supplementation in multiple sclerosis: Symptoms and biomarkers of depression. Journal of the Neurological Sciences. 378: 30-35. PMID 28566173 DOI: 10.1016/J.Jns.2017.04.017  0.699
2017 Signori A, Izquierdo G, Lugaresi A, Hupperts R, Grand'Maison F, Sola P, Horakova D, Havrdova E, Prat A, Girard M, Duquette P, Boz C, Grammond P, Terzi M, Singhal B, et al. Long-term disability trajectories in primary progressive MS patients: A latent class growth analysis. Multiple Sclerosis (Houndmills, Basingstoke, England). 1352458517703800. PMID 28382837 DOI: 10.1177/1352458517703800  0.421
2017 Kalincik T, Brown JW, Robertson N, Willis M, Scolding N, Rice CM, Wilkins A, Pearson O, Ziemssen T, Hutchinson M, McGuigan C, Jokubaitis V, Spelman T, Horakova D, Havrdova E, ... ... Hupperts R, et al. Treatment effectiveness of alemtuzumab compared with natalizumab, fingolimod, and interferon beta in relapsing-remitting multiple sclerosis: a cohort study. The Lancet. Neurology. PMID 28209331 DOI: 10.1016/S1474-4422(17)30007-8  0.368
2017 Brown JWL, Coles A, Horakova D, Havrdova E, Trojano M, Izquierdo G, Prat A, Girard M, Hupperts R, Pesch VV, Ferraro D, Alroughani R, Bergamaschi R, Pucci E, Iuliano G, et al. The effect of disease-modifying treatments on conversion to secondary progressive multiple sclerosis Multiple Sclerosis Journal. 23: 32-34. DOI: 10.1177/1352458517731283  0.373
2016 Claes N, Fraussen J, Vanheusden M, Hellings N, Stinissen P, Van Wijmeersch B, Hupperts R, Somers V. Age-Associated B Cells with Proinflammatory Characteristics Are Expanded in a Proportion of Multiple Sclerosis Patients. Journal of Immunology (Baltimore, Md. : 1950). PMID 27837111 DOI: 10.4049/Jimmunol.1502448  0.412
2016 Muris AH, Smolders J, Rolf L, Thewissen M, Hupperts R, Damoiseaux J. Immune regulatory effects of high dose vitamin D3 supplementation in a randomized controlled trial in relapsing remitting multiple sclerosis patients receiving IFNβ; the SOLARIUM study. Journal of Neuroimmunology. 300: 47-56. PMID 27806875 DOI: 10.1016/J.Jneuroim.2016.09.018  0.737
2016 Gasperini C, Hupperts R, Lycke J, Short C, McNeill M, Zhong J, Mehta LR. Prolonged-release fampridine treatment improved subject-reported impact of multiple sclerosis: Item-level analysis of the MSIS-29. Journal of the Neurological Sciences. 370: 123-131. PMID 27772740 DOI: 10.1016/J.Jns.2016.08.052  0.36
2016 Fraussen J, Claes N, Van Wijmeersch B, van Horssen J, Stinissen P, Hupperts R, Somers V. B cells of multiple sclerosis patients induce autoreactive proinflammatory T cell responses. Clinical Immunology (Orlando, Fla.). PMID 27717695 DOI: 10.1016/J.Clim.2016.10.001  0.454
2016 Lizak N, Lugaresi A, Alroughani R, Lechner-Scott J, Slee M, Havrdova E, Horakova D, Trojano M, Izquierdo G, Duquette P, Girard M, Prat A, Grammond P, Hupperts R, Grand'Maison F, et al. Highly active immunomodulatory therapy ameliorates accumulation of disability in moderately advanced and advanced multiple sclerosis. Journal of Neurology, Neurosurgery, and Psychiatry. PMID 27683916 DOI: 10.1136/Jnnp-2016-313976  0.414
2016 Lorscheider J, Buzzard K, Jokubaitis V, Spelman T, Havrdova E, Horakova D, Trojano M, Izquierdo G, Girard M, Duquette P, Prat A, Lugaresi A, Grand'Maison F, Grammond P, Hupperts R, et al. Defining secondary progressive multiple sclerosis. Brain : a Journal of Neurology. PMID 27401521 DOI: 10.1093/Brain/Aww173  0.412
2016 Rolf L, Damoiseaux J, Hupperts R, Huitinga I, Smolders J. Network of nuclear receptor ligands in multiple sclerosis: Common pathways and interactions of sex-steroids, corticosteroids and vitamin D3-derived molecules. Autoimmunity Reviews. PMID 27395031 DOI: 10.1016/J.Autrev.2016.07.002  0.638
2016 Jongen PJ, Lemmens WA, Hupperts R, Hoogervorst ELj, Schrijver HM, Slettenaar A, de Schryver EL, Boringa J, van Noort E, Donders R. Persistence and adherence in multiple sclerosis patients starting glatiramer acetate treatment: assessment of relationship with care received from multiple disciplines. Patient Preference and Adherence. 10: 909-17. PMID 27307711 DOI: 10.2147/Ppa.S108121  0.368
2016 Knippenberg S, Smolders J, van den Maegdenbergh M, Porro G, Damoiseaux J, Hupperts R. Vitamin D status is negatively correlated with retinal nerve fiber layer thickness in relapsing-remitting MS patients without acute optic neuritis. Multiple Sclerosis (Houndmills, Basingstoke, England). PMID 27301383 DOI: 10.1177/1352458516652950  0.651
2016 Kister I, Spelman T, Alroughani R, Lechner-Scott J, Duquette P, Grand'Maison F, Slee M, Lugaresi A, Barnett M, Grammond P, Iuliano G, Hupperts R, Pucci E, Trojano M, Butzkueven H, et al. Discontinuing disease-modifying therapy in MS after a prolonged relapse-free period: a propensity score-matched study. Journal of Neurology, Neurosurgery, and Psychiatry. PMID 27298148 DOI: 10.1136/Jnnp-2016-313760  0.421
2016 Muris AH, Smolders J, Rolf L, Klinkenberg LJ, van der Linden N, Meex S, Damoiseaux J, Hupperts R. Vitamin D Status Does Not Affect Disability Progression of Patients with Multiple Sclerosis over Three Year Follow-Up. Plos One. 11: e0156122. PMID 27276080 DOI: 10.1371/Journal.Pone.0156122  0.748
2016 Brandt-Wouters E, Gerlach OH, Hupperts RM. The effect of postpartum intravenous immunoglobulins on the relapse rate among patients with multiple sclerosis. International Journal of Gynaecology and Obstetrics: the Official Organ of the International Federation of Gynaecology and Obstetrics. PMID 27177509 DOI: 10.1016/j.ijgo.2016.01.008  0.356
2016 Jokubaitis VG, Spelman T, Kalincik T, Lorscheider J, Havrdova E, Horakova D, Duquette P, Girard M, Prat A, Izquierdo G, Grammond P, Van Pesch V, Pucci E, Grand'Maison F, Hupperts R, et al. Predictors of long-term disability accrual in relapse-onset multiple sclerosis. Annals of Neurology. PMID 27145331 DOI: 10.1002/Ana.24682  0.433
2016 Stewart T, Spelman T, Havrdova E, Horakova D, Trojano M, Izquierdo G, Duquette P, Girard M, Prat A, Lugaresi A, Grand'Maison F, Grammond P, Sola P, Shaygannejad V, Hupperts R, et al. Contribution of different relapse phenotypes to disability in multiple sclerosis. Multiple Sclerosis (Houndmills, Basingstoke, England). PMID 27055805 DOI: 10.1177/1352458516643392  0.422
2016 Rolf L, Muris AH, Hupperts R, Damoiseaux J. Illuminating vitamin D effects on B-cells - the multiple sclerosis perspective. Immunology. PMID 26729321 DOI: 10.1111/imm.12577  0.467
2015 Rojas JI, Patrucco L, Trojano M, Lugaresi A, Izquierdo G, Butzkueven H, Jokubaitis V, Duquette P, Girard M, Grand'Maison F, Grammond P, Oreja-Guevara C, Hupperts R, Boz C, Petersen T, et al. Multiple sclerosis in Latin America: A different disease course severity? A collaborative study from the MSBase Registry. Multiple Sclerosis Journal - Experimental, Translational and Clinical. 1: 2055217315600193. PMID 28607702 DOI: 10.1177/2055217315600193  0.348
2015 Claes N, Fraussen J, Stinissen P, Hupperts R, Somers V. B Cells Are Multifunctional Players in Multiple Sclerosis Pathogenesis: Insights from Therapeutic Interventions. Frontiers in Immunology. 6: 642. PMID 26734009 DOI: 10.3389/Fimmu.2015.00642  0.453
2015 Rolf L, Muris AH, Hupperts R, Damoiseaux J. Illuminating vitamin D effects on B-cells - the multiple sclerosis perspective. Immunology. PMID 26714674 DOI: 10.1111/Imm.12572  0.555
2015 Muris AH, Rolf L, Broen K, Hupperts R, Damoiseaux J, Smolders J. A low vitamin D status at diagnosis is associated with an early conversion to secondary progressive multiple sclerosis. The Journal of Steroid Biochemistry and Molecular Biology. PMID 26598277 DOI: 10.1016/J.Jsbmb.2015.11.009  0.699
2015 Kalincik T, Cutter G, Spelman T, Jokubaitis V, Havrdova E, Horakova D, Trojano M, Izquierdo G, Girard M, Duquette P, Prat A, Lugaresi A, Grand'Maison F, Grammond P, Hupperts R, et al. Defining reliable disability outcomes in multiple sclerosis. Brain : a Journal of Neurology. 138: 3287-98. PMID 26359291 DOI: 10.1093/Brain/Awv258  0.336
2015 Warrender-Sparkes M, Spelman T, Izquierdo G, Trojano M, Lugaresi A, Grand'Maison F, Havrdova E, Horakova D, Boz C, Oreja-Guevara C, Alroughani R, Iuliano G, Duquette P, Girard M, Terzi M, ... Hupperts R, et al. The effect of oral immunomodulatory therapy on treatment uptake and persistence in multiple sclerosis. Multiple Sclerosis (Houndmills, Basingstoke, England). PMID 26199347 DOI: 10.1177/1352458515594041  0.341
2015 Bayas A, Ouallet JC, Kallmann B, Hupperts R, Fulda U, Marhardt K. Adherence to, and effectiveness of, subcutaneous interferon β-1a administered by RebiSmart® in patients with relapsing multiple sclerosis: results of the 1-year, observational SMART study. Expert Opinion On Drug Delivery. 12: 1239-50. PMID 26098143 DOI: 10.1517/17425247.2015.1057567  0.347
2015 Ribbons KA, McElduff P, Boz C, Trojano M, Izquierdo G, Duquette P, Girard M, Grand'Maison F, Hupperts R, Grammond P, Oreja-Guevara C, Petersen T, Bergamaschi R, Giuliani G, Barnett M, et al. Male Sex Is Independently Associated with Faster Disability Accumulation in Relapse-Onset MS but Not in Primary Progressive MS. Plos One. 10: e0122686. PMID 26046348 DOI: 10.1371/Journal.Pone.0122686  0.407
2015 Jokubaitis VG, Spelman T, Kalincik T, Izquierdo G, Grand'Maison F, Duquette P, Girard M, Lugaresi A, Grammond P, Hupperts R, Cabrera-Gomez J, Oreja-Guevara C, Boz C, Giuliani G, Fernández-Bolaños R, et al. Predictors of disability worsening in clinically isolated syndrome. Annals of Clinical and Translational Neurology. 2: 479-91. PMID 26000321 DOI: 10.1002/Acn3.187  0.321
2015 Hupperts R, Lycke J, Short C, Gasperini C, McNeill M, Medori R, Tofil-Kaluza A, Hovenden M, Mehta LR, Elkins J. Prolonged-release fampridine and walking and balance in MS: randomised controlled MOBILE trial. Multiple Sclerosis (Houndmills, Basingstoke, England). PMID 25921050 DOI: 10.1177/1352458515581436  0.432
2015 Bergamaschi R, Montomoli C, Mallucci G, Lugaresi A, Izquierdo G, Grand'Maison F, Duquette P, Shaygannejad V, Alroughani R, Grammond P, Boz C, Iuliano G, Zwanikken C, Petersen T, Lechner-Scott J, ... Hupperts R, et al. BREMSO: a simple score to predict early the natural course of multiple sclerosis. European Journal of Neurology : the Official Journal of the European Federation of Neurological Societies. 22: 981-9. PMID 25808578 DOI: 10.1111/Ene.12696  0.452
2015 Peelen E, Muris AH, Damoiseaux J, Knippenberg S, Broens K, Smolders J, Cohen Tervaert JW, Hupperts R, Thewissen M. GM-CSF production by CD4+ T cells in MS patients: regulation by regulatory T cells and vitamin D. Journal of Neuroimmunology. 280: 36-42. PMID 25773153 DOI: 10.1016/J.Jneuroim.2015.02.007  0.664
2015 He A, Spelman T, Jokubaitis V, Havrdova E, Horakova D, Trojano M, Lugaresi A, Izquierdo G, Grammond P, Duquette P, Girard M, Pucci E, Iuliano G, Alroughani R, Oreja-Guevara C, ... ... Hupperts R, et al. Comparison of switch to fingolimod or interferon beta/glatiramer acetate in active multiple sclerosis. Jama Neurology. 72: 405-13. PMID 25665031 DOI: 10.1001/Jamaneurol.2014.4147  0.401
2015 Kalincik T, Horakova D, Spelman T, Jokubaitis V, Trojano M, Lugaresi A, Izquierdo G, Rozsa C, Grammond P, Alroughani R, Duquette P, Girard M, Pucci E, Lechner-Scott J, Slee M, ... ... Hupperts R, et al. Switch to natalizumab versus fingolimod in active relapsing-remitting multiple sclerosis. Annals of Neurology. 77: 425-35. PMID 25546031 DOI: 10.1002/Ana.24339  0.383
2015 Kalincik T, Jokubaitis V, Izquierdo G, Duquette P, Girard M, Grammond P, Lugaresi A, Oreja-Guevara C, Bergamaschi R, Hupperts R, Grand'Maison F, Pucci E, Van Pesch V, Boz C, Iuliano G, et al. Comparative effectiveness of glatiramer acetate and interferon beta formulations in relapsing-remitting multiple sclerosis. Multiple Sclerosis (Houndmills, Basingstoke, England). 21: 1159-71. PMID 25480857 DOI: 10.1177/1352458514559865  0.392
2015 Peelen E, Damoiseaux J, Muris AH, Knippenberg S, Smolders J, Hupperts R, Thewissen M. Increased inflammasome related gene expression profile in PBMC may facilitate T helper 17 cell induction in multiple sclerosis. Molecular Immunology. 63: 521-9. PMID 25458313 DOI: 10.1016/J.Molimm.2014.10.008  0.62
2015 Hupperts R, Becker V, Friedrich J, Gobbi C, Salgado AV, Sperling B, You X. Multiple sclerosis patients treated with intramuscular IFN-β-1a autoinjector in a real-world setting: prospective evaluation of treatment persistence, adherence, quality of life and satisfaction. Expert Opinion On Drug Delivery. 12: 15-25. PMID 25430947 DOI: 10.1517/17425247.2015.989209  0.358
2014 Claes N, Dhaeze T, Fraussen J, Broux B, Van Wijmeersch B, Stinissen P, Hupperts R, Hellings N, Somers V. Compositional changes of B and T cell subtypes during fingolimod treatment in multiple sclerosis patients: a 12-month follow-up study. Plos One. 9: e111115. PMID 25360562 DOI: 10.1371/Journal.Pone.0111115  0.468
2014 Spelman T, Gray O, Trojano M, Petersen T, Izquierdo G, Lugaresi A, Hupperts R, Bergamaschi R, Duquette P, Grammond P, Giuliani G, Boz C, Verheul F, Oreja-Guevara C, Barnett M, et al. Seasonal variation of relapse rate in multiple sclerosis is latitude dependent. Annals of Neurology. 76: 880-90. PMID 25283272 DOI: 10.1002/Ana.24287  0.327
2014 Muris AH, Rolf L, Damoiseaux J, Koeman E, Hupperts R. Fingolimod in active multiple sclerosis: an impressive decrease in Gd-enhancing lesions. Bmc Neurology. 14: 164. PMID 25138918 DOI: 10.1186/S12883-014-0164-5  0.36
2014 de Bock L, Somers K, Fraussen J, Hendriks JJ, van Horssen J, Rouwette M, Hellings N, Villar LM, Alvarez-Cermeño JC, Espiño M, Hupperts R, Jongen P, Damoiseaux J, Verbeek MM, De Deyn PP, et al. Sperm-associated antigen 16 is a novel target of the humoral autoimmune response in multiple sclerosis. Journal of Immunology (Baltimore, Md. : 1950). 193: 2147-56. PMID 25086173 DOI: 10.4049/Jimmunol.1401166  0.462
2014 Hupperts R, Ghazi-Visser L, Martins Silva A, Arvanitis M, Kuusisto H, Marhardt K, Vlaikidis N. The STAR Study: a real-world, international, observational study of the safety and tolerability of, and adherence to, serum-free subcutaneous interferon β-1a in patients with relapsing multiple sclerosis. Clinical Therapeutics. 36: 1946-57. PMID 24811754 DOI: 10.1016/J.Clinthera.2014.04.002  0.393
2014 Kalincik T, Buzzard K, Jokubaitis V, Trojano M, Duquette P, Izquierdo G, Girard M, Lugaresi A, Grammond P, Grand'Maison F, Oreja-Guevara C, Boz C, Hupperts R, Petersen T, Giuliani G, et al. Risk of relapse phenotype recurrence in multiple sclerosis. Multiple Sclerosis (Houndmills, Basingstoke, England). 20: 1511-22. PMID 24777276 DOI: 10.1177/1352458514528762  0.347
2014 Rolf L, Muris AH, Hupperts R, Damoiseaux J. Vitamin D effects on B cell function in autoimmunity. Annals of the New York Academy of Sciences. 1317: 84-91. PMID 24761763 DOI: 10.1111/Nyas.12440  0.482
2014 Rolf L, Muris AH, Damoiseaux J, van Daele M, Hupperts R. Paroxysmal atrial fibrillation after initiation of fingolimod for multiple sclerosis treatment. Neurology. 82: 1008-9. PMID 24523479 DOI: 10.1212/Wnl.0000000000000218  0.429
2014 Cambron M, Mostert J, Haentjens P, D'Hooghe M, Nagels G, Willekens B, Heersema D, Debruyne J, Van Hecke W, Algoed L, De Klippel N, Fosselle E, Laureys G, Merckx H, Van Wijmeersch B, ... ... Hupperts R, et al. Fluoxetine in progressive multiple sclerosis (FLUOX-PMS): study protocol for a randomized controlled trial. Trials. 15: 37. PMID 24460863 DOI: 10.1186/1745-6215-15-37  0.396
2014 Hughes SE, Spelman T, Gray OM, Boz C, Trojano M, Lugaresi A, Izquierdo G, Duquette P, Girard M, Grand'Maison F, Grammond P, Oreja-Guevara C, Hupperts R, Bergamaschi R, Giuliani G, et al. Predictors and dynamics of postpartum relapses in women with multiple sclerosis. Multiple Sclerosis (Houndmills, Basingstoke, England). 20: 739-46. PMID 24107309 DOI: 10.1177/1352458513507816  0.383
2014 Smolders J, Peelen E, Thewissen M, Menheere P, Damoiseaux J, Hupperts R. Circulating vitamin D binding protein levels are not associated with relapses or with vitamin D status in multiple sclerosis. Multiple Sclerosis (Houndmills, Basingstoke, England). 20: 433-7. PMID 23959712 DOI: 10.1177/1352458513500552  0.715
2014 Knippenberg S, Damoiseaux J, Bol Y, Hupperts R, Taylor BV, Ponsonby AL, Dwyer T, Simpson S, van der Mei IA. Higher levels of reported sun exposure, and not vitamin D status, are associated with less depressive symptoms and fatigue in multiple sclerosis. Acta Neurologica Scandinavica. 129: 123-31. PMID 23763464 DOI: 10.1111/Ane.12155  0.441
2013 Kalincik T, Vivek V, Jokubaitis V, Lechner-Scott J, Trojano M, Izquierdo G, Lugaresi A, Grand'maison F, Hupperts R, Oreja-Guevara C, Bergamaschi R, Iuliano G, Alroughani R, Van Pesch V, Amato MP, et al. Sex as a determinant of relapse incidence and progressive course of multiple sclerosis. Brain : a Journal of Neurology. 136: 3609-17. PMID 24142147 DOI: 10.1093/Brain/Awt281  0.357
2013 Disanto G, Handel AE, Damoiseaux J, Hupperts R, Giovannoni G, Smolders J, Ramagopalan SV. Vitamin D supplementation and antibodies against the Epstein-Barr virus in multiple sclerosis patients. Multiple Sclerosis (Houndmills, Basingstoke, England). 19: 1679-80. PMID 23828870 DOI: 10.1177/1352458513494494  0.689
2013 Fraussen J, Vrolix K, Claes N, Martinez-Martinez P, Losen M, Hupperts R, Van Wijmeersch B, Espiño M, Villar LM, De Baets MH, Stinissen P, Somers V. Autoantigen induced clonal expansion in immortalized B cells from the peripheral blood of multiple sclerosis patients. Journal of Neuroimmunology. 261: 98-107. PMID 23746373 DOI: 10.1016/J.Jneuroim.2013.05.002  0.438
2013 Rouwette M, Noben JP, Van Horssen J, Van Wijmeersch B, Hupperts R, Jongen PJ, Verbeek MM, De Deyn PP, Stinissen P, Somers V. Identification of coronin-1a as a novel antibody target for clinically isolated syndrome and multiple sclerosis. Journal of Neurochemistry. 126: 483-92. PMID 23745754 DOI: 10.1111/Jnc.12335  0.389
2013 Kalincik T, Spelman T, Trojano M, Duquette P, Izquierdo G, Grammond P, Lugaresi A, Hupperts R, Cristiano E, Van Pesch V, Grand'maison F, La Spitaleri D, Rio ME, Flechter S, Oreja-Guevara C, et al. Persistence on therapy and propensity matched outcome comparison of two subcutaneous interferon beta 1a dosages for multiple sclerosis. Plos One. 8: e63480. PMID 23704913 DOI: 10.1371/Journal.Pone.0063480  0.353
2013 Karampampa K, Gustavsson A, van Munster ET, Hupperts RM, Sanders EA, Mostert J, Sinnige OL, de Graaf J, Pop P, Miltenburger C, Groot MT, Relleke M, van der Hel WS. Treatment experience, burden, and unmet needs (TRIBUNE) in Multiple Sclerosis study: the costs and utilities of MS patients in The Netherlands. Journal of Medical Economics. 16: 939-50. PMID 23692584 DOI: 10.3111/13696998.2013.807267  0.321
2013 Peelen E, Thewissen M, Knippenberg S, Smolders J, Muris AH, Menheere P, Tervaert JW, Hupperts R, Damoiseaux J. Fraction of IL-10+ and IL-17+ CD8 T cells is increased in MS patients in remission and during a relapse, but is not influenced by immune modulators. Journal of Neuroimmunology. 258: 77-84. PMID 23517930 DOI: 10.1016/J.Jneuroim.2013.02.014  0.654
2013 Verheul F, Smolders J, Trojano M, Lepore V, Zwanikken C, Amato MP, Grand'maison F, Butzkueven H, Marrosu M, Duquette P, Comi G, Izquierdo G, Grammond P, Lus G, Petersen T, ... ... Hupperts R, et al. Fluctuations of MS births and UV-light exposure. Acta Neurologica Scandinavica. 127: 301-8. PMID 22970985 DOI: 10.1111/Ane.12007  0.653
2013 Peelen E, Rijkers G, Meerveld-Eggink A, Meijvis S, Vogt M, Cohen Tervaert JW, Hupperts R, Damoiseaux J. Relatively high serum vitamin D levels do not impair the antibody response to encapsulated bacteria. European Journal of Clinical Microbiology & Infectious Diseases : Official Publication of the European Society of Clinical Microbiology. 32: 61-9. PMID 22875191 DOI: 10.1007/S10096-012-1714-7  0.452
2012 Trojano M, Lucchese G, Graziano G, Taylor BV, Simpson S, Lepore V, Grand'maison F, Duquette P, Izquierdo G, Grammond P, Amato MP, Bergamaschi R, Giuliani G, Boz C, Hupperts R, et al. Geographical variations in sex ratio trends over time in multiple sclerosis. Plos One. 7: e48078. PMID 23133550 DOI: 10.1371/Journal.Pone.0048078  0.404
2012 Rouwette M, Somers K, Govarts C, De Deyn PP, Hupperts R, Van Wijmeersch B, De Jong BA, Verbeek MM, Van Pesch V, Sindic C, Villar LM, Álvarez-Cermeño JC, Stinissen P, Somers V. Novel cerebrospinal fluid and serum autoantibody targets for clinically isolated syndrome. Journal of Neurochemistry. 123: 568-77. PMID 22958230 DOI: 10.1111/Jnc.12005  0.369
2012 Muris AH, Damoiseaux J, Smolders J, Cohen Tervaert JW, Hupperts R, Thewissen M. Intracellular IL-10 detection in T cells by flowcytometry: the use of protein transport inhibitors revisited. Journal of Immunological Methods. 381: 59-65. PMID 22565155 DOI: 10.1016/J.Jim.2012.04.011  0.551
2012 Kister I, Chamot E, Cutter G, Bacon TE, Jokubaitis VG, Hughes SE, Gray OM, Trojano M, Izquierdo G, Grand'Maison F, Duquette P, Lugaresi A, Grammond P, Boz C, Hupperts R, et al. Increasing age at disability milestones among MS patients in the MSBase Registry. Journal of the Neurological Sciences. 318: 94-9. PMID 22507751 DOI: 10.1016/J.Jns.2012.03.017  0.432
2012 Grimaldi L, Barkhof F, Beelke M, Burton J, Holmoy T, Hupperts R, Killestein J, Rieckmann P, Schluep M, Smolders J. A randomized trial of high-dose vitamin D2 in relapsing-remitting multiple sclerosis. Neurology. 78: 841. PMID 22411961 DOI: 10.1212/01.Wnl.0000413180.13413.Ce  0.646
2012 Bol Y, Smolders J, Duits A, Lange IM, Romberg-Camps M, Hupperts R. Fatigue and heat sensitivity in patients with multiple sclerosis. Acta Neurologica Scandinavica. 126: 384-9. PMID 22404677 DOI: 10.1111/J.1600-0404.2012.01660.X  0.623
2012 Hughes S, Spelman T, Trojano M, Lugaresi A, Izquierdo G, Grand'maison F, Duquette P, Girard M, Grammond P, Oreja-Guevara C, Hupperts R, Boz C, Bergamaschi R, Giuliani G, Rio ME, et al. The Kurtzke EDSS rank stability increases 4 years after the onset of multiple sclerosis: results from the MSBase Registry. Journal of Neurology, Neurosurgery, and Psychiatry. 83: 305-10. PMID 22205675 DOI: 10.1136/Jnnp-2011-301051  0.433
2012 Lechner-Scott J, Spencer B, de Malmanche T, Attia J, Fitzgerald M, Trojano M, Grand'Maison F, Gomez JA, Izquierdo G, Duquette P, Girard M, Grammond P, Oreja-Guevara C, Hupperts R, Bergamaschi R, et al. The frequency of CSF oligoclonal banding in multiple sclerosis increases with latitude. Multiple Sclerosis (Houndmills, Basingstoke, England). 18: 974-82. PMID 22185806 DOI: 10.1177/1352458511431729  0.441
2012 Hughes S, Spelman T, Gray O, Boz C, Trojano M, Zwanikken C, Lugaresi A, Izquierdo J, Duquette P, Girard M, Grand'Maison F, Grammond P, Oreja-Guevara C, Hupperts R, Petersen T, et al. EXPOSURE TO INTERFERON-β THERAPY IN EARLY PREGNANCY: A LITERATURE REVIEW OF PREGNANCY OUTCOMES IN WOMEN WITH MULTIPLE SCLEROSIS Journal of Neurology, Neurosurgery & Psychiatry. 83: A17.2-A17. DOI: 10.1136/Jnnp-2012-304200A.64  0.334
2012 Knippenberg S, Bol Y, Smolders J, Hupperts R, Damoiseaux J. Response: Relationship between vitamin D and depression in multiple sclerosis Acta Neurologica Scandinavica. 125: e26-e27. DOI: 10.1111/J.1600-0404.2011.01640.X  0.643
2011 Peelen E, Damoiseaux J, Smolders J, Knippenberg S, Menheere P, Tervaert JW, Hupperts R, Thewissen M. Th17 expansion in MS patients is counterbalanced by an expanded CD39+ regulatory T cell population during remission but not during relapse. Journal of Neuroimmunology. 240: 97-103. PMID 22035960 DOI: 10.1016/J.Jneuroim.2011.09.013  0.686
2011 Knippenberg S, Peelen E, Smolders J, Thewissen M, Menheere P, Cohen Tervaert JW, Hupperts R, Damoiseaux J. Reduction in IL-10 producing B cells (Breg) in multiple sclerosis is accompanied by a reduced naïve/memory Breg ratio during a relapse but not in remission. Journal of Neuroimmunology. 239: 80-6. PMID 21940055 DOI: 10.1016/J.Jneuroim.2011.08.019  0.69
2011 Knippenberg S, Smolders J, Thewissen M, Peelen E, Tervaert JW, Hupperts R, Damoiseaux J. Effect of vitamin D(3) supplementation on peripheral B cell differentiation and isotype switching in patients with multiple sclerosis. Multiple Sclerosis (Houndmills, Basingstoke, England). 17: 1418-23. PMID 21690147 DOI: 10.1177/1352458511412655  0.721
2011 Peelen E, Knippenberg S, Muris AH, Thewissen M, Smolders J, Tervaert JW, Hupperts R, Damoiseaux J. Effects of vitamin D on the peripheral adaptive immune system: a review. Autoimmunity Reviews. 10: 733-43. PMID 21621002 DOI: 10.1016/J.Autrev.2011.05.002  0.686
2011 Smolders J, Hupperts R, Barkhof F, Grimaldi LM, Holmoy T, Killestein J, Rieckmann P, Schluep M, Vieth R, Hostalek U, Ghazi-Visser L, Beelke M. Efficacy of vitamin D3 as add-on therapy in patients with relapsing-remitting multiple sclerosis receiving subcutaneous interferon β-1a: a Phase II, multicenter, double-blind, randomized, placebo-controlled trial. Journal of the Neurological Sciences. 311: 44-9. PMID 21620416 DOI: 10.1016/J.Jns.2011.04.013  0.742
2011 Smolders J, Thewissen M, Theunissen R, Peelen E, Knippenberg S, Menheere P, Cohen Tervaert JW, Hupperts R, Damoiseaux J. Vitamin D-related gene expression profiles in immune cells of patients with relapsing remitting multiple sclerosis. Journal of Neuroimmunology. 235: 91-7. PMID 21507492 DOI: 10.1016/J.Jneuroim.2011.03.012  0.69
2011 Jongen PJ, Hengstman G, Hupperts R, Schrijver H, Gilhuis J, Vliegen JH, Hoogervorst E, van Huizen M, van Munster E, Samijn J, de Schryver E, Siepman T, Tonk M, Zandbergen E, ten Holter J, et al. Drug adherence and multidisciplinary care in patients with multiple sclerosis: protocol of a prospective, web-based, patient-centred, nation-wide, Dutch cohort study in glatiramer acetate treated patients (CAIR study). Bmc Neurology. 11: 40. PMID 21450086 DOI: 10.1186/1471-2377-11-40  0.335
2011 Knippenberg S, Bol Y, Damoiseaux J, Hupperts R, Smolders J. Vitamin D status in patients with MS is negatively correlated with depression, but not with fatigue. Acta Neurologica Scandinavica. 124: 171-5. PMID 20880265 DOI: 10.1111/J.1600-0404.2010.01447.X  0.688
2010 Smolders J, Peelen E, Thewissen M, Cohen Tervaert JW, Menheere P, Hupperts R, Damoiseaux J. Safety and T cell modulating effects of high dose vitamin D3 supplementation in multiple sclerosis. Plos One. 5: e15235. PMID 21179201 DOI: 10.1371/Journal.Pone.0015235  0.733
2010 Bol Y, Duits AA, Vertommen-Mertens CE, Hupperts RM, Romberg-Camps MJ, Verhey FR, Vlaeyen JW. The contribution of disease severity, depression and negative affectivity to fatigue in multiple sclerosis: a comparison with ulcerative colitis. Journal of Psychosomatic Research. 69: 43-9. PMID 20630262 DOI: 10.1016/j.jpsychores.2009.11.011  0.314
2010 Smolders J, Menheere P, Thewissen M, Peelen E, Tervaert JW, Hupperts R, Damoiseaux J. Regulatory T cell function correlates with serum 25-hydroxyvitamin D, but not with 1,25-dihydroxyvitamin D, parathyroid hormone and calcium levels in patients with relapsing remitting multiple sclerosis. The Journal of Steroid Biochemistry and Molecular Biology. 121: 243-6. PMID 20211254 DOI: 10.1016/J.Jsbmb.2010.03.001  0.698
2010 Vogt MH, ten Kate J, Drent RJ, Polman CH, Hupperts R. Increased osteopontin plasma levels in multiple sclerosis patients correlate with bone-specific markers. Multiple Sclerosis (Houndmills, Basingstoke, England). 16: 443-9. PMID 20086024 DOI: 10.1177/1352458509359723  0.382
2009 Govarts C, Somers K, Hupperts R, Stinissen P, Somers V. Analysis of antibody reactivity in paired cerebrospinal fluid and serum of a relapsing remitting multiple sclerosis patient. Autoimmunity. 42: 699-704. PMID 19835487 DOI: 10.3109/08916930903176513  0.359
2009 Smolders J, Damoiseaux J, Menheere P, Tervaert JW, Hupperts R. Association study on two vitamin D receptor gene polymorphisms and vitamin D metabolites in multiple sclerosis. Annals of the New York Academy of Sciences. 1173: 515-20. PMID 19758194 DOI: 10.1111/J.1749-6632.2009.04656.X  0.702
2009 Damoiseaux J, Peeters L, Hupperts R, Boreas A, ten Cate H, Tervaert JW. Prevalence of anticardiolipin antibodies in patient cohorts with distinct clinical manifestations of the antiphospholipid syndrome. Annals of the New York Academy of Sciences. 1173: 146-51. PMID 19758143 DOI: 10.1111/J.1749-6632.2009.04643.X  0.39
2009 Smolders J, Thewissen M, Peelen E, Menheere P, Tervaert JW, Damoiseaux J, Hupperts R. Vitamin D status is positively correlated with regulatory T cell function in patients with multiple sclerosis. Plos One. 4: e6635. PMID 19675671 DOI: 10.1371/Journal.Pone.0006635  0.743
2009 Smolders J, Peelen E, Thewissen M, Menheere P, Tervaert JW, Hupperts R, Damoiseaux J. The relevance of vitamin D receptor gene polymorphisms for vitamin D research in multiple sclerosis. Autoimmunity Reviews. 8: 621-6. PMID 19393206 DOI: 10.1016/J.Autrev.2009.02.009  0.715
2009 Smolders J, Damoiseaux J, Menheere P, Tervaert JW, Hupperts R. Fok-I vitamin D receptor gene polymorphism (rs10735810) and vitamin D metabolism in multiple sclerosis. Journal of Neuroimmunology. 207: 117-21. PMID 19178954 DOI: 10.1016/J.Jneuroim.2008.12.011  0.718
2009 De Stefano N, Filippi M, Confavreux C, Vermersch P, Simu M, Sindic C, Hupperts R, Bajenaru O, Edan G, Grimaldi L, Marginean I, Medaer R, Orefice G, Pascu I, Pelletier J, et al. The results of two multicenter, open-label studies assessing efficacy, tolerability and safety of protiramer, a high molecular weight synthetic copolymeric mixture, in patients with relapsing-remitting multiple sclerosis. Multiple Sclerosis (Houndmills, Basingstoke, England). 15: 238-43. PMID 18987103 DOI: 10.1177/1352458508098269  0.307
2009 Somers K, Hupperts R, Zwanikken C, Stinissen P, Somers V. S.32. Antibodies Against Sperm Associated Antigen 16 as a Novel Disease Marker for Multiple Sclerosis Clinical Immunology. 131: S141-S142. DOI: 10.1016/J.Clim.2009.03.416  0.324
2009 Fraussen J, Vrolix K, Martinez-Martinez P, Hupperts R, Van Diepen A, Meulemans E, De Baets M, Stinissen P, Somers V. F.133. Antibody-producing Monoclonal B Cell Lines from Multiple Sclerosis Patients Obtained by B Cell Immortalization Clinical Immunology. 131: S129-S130. DOI: 10.1016/J.Clim.2009.03.383  0.321
2008 Smolders J, Menheere P, Kessels A, Damoiseaux J, Hupperts R. Association of vitamin D metabolite levels with relapse rate and disability in multiple sclerosis. Multiple Sclerosis (Houndmills, Basingstoke, England). 14: 1220-4. PMID 18653736 DOI: 10.1177/1352458508094399  0.725
2008 Somers V, Govarts C, Somers K, Hupperts R, Medaer R, Stinissen P. Autoantibody profiling in multiple sclerosis reveals novel antigenic candidates. Journal of Immunology (Baltimore, Md. : 1950). 180: 3957-63. PMID 18322204 DOI: 10.4049/Jimmunol.180.6.3957  0.455
2008 Smolders J, Damoiseaux J, Menheere P, Hupperts R. Vitamin D as an immune modulator in multiple sclerosis, a review. Journal of Neuroimmunology. 194: 7-17. PMID 18177949 DOI: 10.1016/J.Jneuroim.2007.11.014  0.723
2008 Venken K, Hellings N, Thewissen M, Somers V, Hensen K, Rummens JL, Medaer R, Hupperts R, Stinissen P. Compromised CD4+ CD25(high) regulatory T-cell function in patients with relapsing-remitting multiple sclerosis is correlated with a reduced frequency of FOXP3-positive cells and reduced FOXP3 expression at the single-cell level. Immunology. 123: 79-89. PMID 17897326 DOI: 10.1111/J.1365-2567.2007.02690.X  0.459
2007 Govarts C, Somers K, Hupperts R, Stinissen P, Somers V. Exploring cDNA phage display for autoantibody profiling in the serum of multiple sclerosis patients: optimization of the selection procedure. Annals of the New York Academy of Sciences. 1109: 372-84. PMID 17785326 DOI: 10.1196/Annals.1398.043  0.434
2006 Noben JP, Dumont D, Kwasnikowska N, Verhaert P, Somers V, Hupperts R, Stinissen P, Robben J. Lumbar cerebrospinal fluid proteome in multiple sclerosis: characterization by ultrafiltration, liquid chromatography, and mass spectrometry. Journal of Proteome Research. 5: 1647-57. PMID 16823972 DOI: 10.1021/Pr0504788  0.348
2005 Bol Y, Duits A, Hupperts R, Verhey F. De neuropsychologie van multiple sclerose Neuropraxis. 9: 102-107. DOI: 10.1007/Bf03079050  0.426
2003 Zhang X, Hupperts R, De Baets M. Monoclonal antibody therapy in experimental allergic encephalomyelitis and multiple sclerosis. Immunologic Research. 28: 61-78. PMID 12947225 DOI: 10.1385/Ir:28:1:61  0.452
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