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Martin Wühr, Ph.D. - Publications

Affiliations: 
2005-2010 Systems Biology Harvard University, Cambridge, MA, United States 
 2011-2016 Department of Cell Biology Harvard Medical School, Boston, MA, United States 
 2016- Department of Molecular Biology Princeton University, Princeton, NJ 
Area:
Proteomics, Systems Biochemistry, Cell Biology, Development
Website:
http://scholar.princeton.edu/wuehr/
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40 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Hart EM, Gupta M, Wühr M, Silhavy TJ. The gain-of-function allele bypasses the essential requirement for BamD in β-barrel outer membrane protein assembly. Proceedings of the National Academy of Sciences of the United States of America. PMID 32675245 DOI: 10.1073/Pnas.2007696117  0.335
2020 Cao WX, Kabelitz S, Gupta M, Yeung E, Lin S, Rammelt C, Ihling C, Pekovic F, Low TCH, Siddiqui NU, Cheng MHK, Angers S, Smibert CA, Wühr M, Wahle E, et al. Precise Temporal Regulation of Post-transcriptional Repressors Is Required for an Orderly Drosophila Maternal-to-Zygotic Transition. Cell Reports. 31: 107783. PMID 32579915 DOI: 10.1016/J.Celrep.2020.107783  0.328
2020 Yeung E, McFann S, Marsh L, Dufresne E, Filippi S, Harrington HA, Shvartsman SY, Wühr M. Inference of Multisite Phosphorylation Rate Constants and Their Modulation by Pathogenic Mutations. Current Biology : Cb. PMID 32059766 DOI: 10.1016/J.Cub.2019.12.052  0.302
2019 Stadlmeier M, Runtsch LS, Streshnev F, Wühr M, Carell T. A Click-chemistry based enrichable cross-linker for structural and protein interaction analysis by mass spectrometry. Chembiochem : a European Journal of Chemical Biology. PMID 31593346 DOI: 10.1002/Cbic.201900611  0.334
2019 Peshkin L, Gupta M, Ryazanova L, Wühr M. Bayesian Confidence Intervals for Multiplexed Proteomics Integrate Ion-Statistics with Peptide Quantification Concordance. Molecular & Cellular Proteomics : McP. PMID 31311848 DOI: 10.1074/Mcp.Tir119.001317  0.333
2019 Hart EM, Gupta M, Wühr M, Silhavy TJ. The Synthetic Phenotype of Δ Δ Double Mutants Results from a Lethal Jamming of the Bam Complex by the Lipoprotein RcsF. Mbio. 10. PMID 31113901 DOI: 10.1128/Mbio.00662-19  0.361
2019 Tye BW, Commins N, Ryazanova LV, Wühr M, Springer M, Pincus D, Churchman LS. Proteotoxicity from aberrant ribosome biogenesis compromises cell fitness. Elife. 8. PMID 30843788 DOI: 10.7554/Elife.43002  0.591
2019 Nguyen T, Mitchison TJ, Wühr M. Immunofluorescence of Microtubule Assemblies in Amphibian Oocytes and Early Embryos. Methods in Molecular Biology (Clifton, N.J.). 1920: 17-32. PMID 30737683 DOI: 10.1007/978-1-4939-9009-2_2  0.675
2019 Pappireddi N, Martin L, Wühr M. A Review on Quantitative Multiplexed Proteomics. Chembiochem : a European Journal of Chemical Biology. PMID 30609196 DOI: 10.1002/Cbic.201800650  0.344
2019 Tye BW, Commins N, Ryazanova LV, Wühr M, Springer M, Pincus D, Churchman LS. Author response: Proteotoxicity from aberrant ribosome biogenesis compromises cell fitness Elife. DOI: 10.7554/Elife.43002.031  0.531
2018 Nguyen T, Pappireddi N, Wühr M. Proteomics of nucleocytoplasmic partitioning. Current Opinion in Chemical Biology. 48: 55-63. PMID 30472625 DOI: 10.1016/J.Cbpa.2018.10.027  0.416
2018 Sonnett M, Gupta M, Nguyen T, Wühr M. Quantitative Proteomics for Xenopus Embryos II, Data Analysis. Methods in Molecular Biology (Clifton, N.J.). 1865: 195-215. PMID 30151768 DOI: 10.1007/978-1-4939-8784-9_14  0.364
2018 Gupta M, Sonnett M, Ryazanova L, Presler M, Wühr M. Quantitative Proteomics of Xenopus Embryos I, Sample Preparation. Methods in Molecular Biology (Clifton, N.J.). 1865: 175-194. PMID 30151767 DOI: 10.1007/978-1-4939-8784-9_13  0.334
2017 Presler M, Van Itallie E, Klein AM, Kunz R, Coughlin ML, Peshkin L, Gygi SP, Wühr M, Kirschner MW. Proteomics of phosphorylation and protein dynamics during fertilization and meiotic exit in the Xenopus egg. Proceedings of the National Academy of Sciences of the United States of America. 114: E10838-E10847. PMID 29183978 DOI: 10.1073/Pnas.1709207114  0.763
2017 Tassan JP, Wühr M, Hatte G, Kubiak J. Asymmetries in Cell Division, Cell Size, and Furrowing in the Xenopus laevis Embryo. Results and Problems in Cell Differentiation. 61: 243-260. PMID 28409308 DOI: 10.1007/978-3-319-53150-2_11  0.435
2017 Hasley A, Chavez S, Danilchik M, Wühr M, Pelegri F. Vertebrate Embryonic Cleavage Pattern Determination. Advances in Experimental Medicine and Biology. 953: 117-171. PMID 27975272 DOI: 10.1007/978-3-319-46095-6_4  0.391
2016 Erickson BK, Rose CM, Braun CR, Erickson AR, Knott J, McAlister GC, Wühr M, Paulo JA, Everley RA, Gygi SP. A Strategy to Combine Sample Multiplexing with Targeted Proteomics Assays for High-Throughput Protein Signature Characterization. Molecular Cell. PMID 28065596 DOI: 10.1016/J.Molcel.2016.12.005  0.453
2016 Pierre A, Sallé J, Wühr M, Minc N. Generic Theoretical Models to Predict Division Patterns of Cleaving Embryos. Developmental Cell. 39: 667-682. PMID 27997824 DOI: 10.1016/J.Devcel.2016.11.018  0.315
2016 Boke E, Ruer M, Wühr M, Coughlin M, Lemaitre R, Gygi SP, Alberti S, Drechsel D, Hyman AA, Mitchison TJ. Amyloid-like Self-Assembly of a Cellular Compartment. Cell. 166: 637-650. PMID 27471966 DOI: 10.1016/J.Cell.2016.06.051  0.726
2015 Peshkin L, Wühr M, Pearl E, Haas W, Freeman RM, Gerhart JC, Klein AM, Horb M, Gygi SP, Kirschner MW. On the Relationship of Protein and mRNA Dynamics in Vertebrate Embryonic Development. Developmental Cell. 35: 383-94. PMID 26555057 DOI: 10.1016/J.Devcel.2015.10.010  0.767
2015 Wühr M, Güttler T, Peshkin L, McAlister GC, Sonnett M, Ishihara K, Groen AC, Presler M, Erickson BK, Mitchison TJ, Kirschner MW, Gygi SP. The Nuclear Proteome of a Vertebrate. Current Biology : Cb. 25: 2663-71. PMID 26441354 DOI: 10.1016/J.Cub.2015.08.047  0.766
2015 Braun CR, Bird GH, Wühr M, Erickson BK, Rad R, Walensky LD, Gygi SP, Haas W. Generation of Multiple Reporter Ions from a Single Isobaric Reagent Increases Multiplexing Capacity for Quantitative Proteomics. Analytical Chemistry. 87: 9855-63. PMID 26308379 DOI: 10.1021/Acs.Analchem.5B02307  0.377
2015 Mitchison TJ, Ishihara K, Nguyen P, Wühr M. Size Scaling of Microtubule Assemblies in Early Xenopus Embryos. Cold Spring Harbor Perspectives in Biology. PMID 26261283 DOI: 10.1101/Cshperspect.A019182  0.68
2015 Huttlin EL, Ting L, Bruckner RJ, Gebreab F, Gygi MP, Szpyt J, Tam S, Zarraga G, Colby G, Baltier K, Dong R, Guarani V, Vaites LP, Ordureau A, Rad R, et al. The BioPlex Network: A Systematic Exploration of the Human Interactome. Cell. 162: 425-40. PMID 26186194 DOI: 10.1016/J.Cell.2015.06.043  0.768
2015 Huttlin EL, Ting L, Bruckner RJ, Gebreab F, Gygi MP, Szpyt J, Tam S, Zarraga G, Colby G, Baltier K, Dong R, Guarani V, Vaites LP, Ordureau A, Rad R, et al. The BioPlex Network: A Systematic Exploration of the Human Interactome Cell. 162: 425-440. DOI: 10.1016/j.cell.2015.06.043  0.725
2014 Nguyen PA, Groen AC, Loose M, Ishihara K, Wühr M, Field CM, Mitchison TJ. Spatial organization of cytokinesis signaling reconstituted in a cell-free system. Science (New York, N.Y.). 346: 244-7. PMID 25301629 DOI: 10.1126/Science.1256773  0.781
2014 Ishihara K, Nguyen PA, Wühr M, Groen AC, Field CM, Mitchison TJ. Organization of early frog embryos by chemical waves emanating from centrosomes. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 369. PMID 25047608 DOI: 10.1098/Rstb.2013.0454  0.765
2014 Wühr M, Freeman RM, Presler M, Horb ME, Peshkin L, Gygi SP, Kirschner MW. Deep proteomics of the Xenopus laevis egg using an mRNA-derived reference database. Current Biology : Cb. 24: 1467-75. PMID 24954049 DOI: 10.1016/J.Cub.2014.05.044  0.687
2014 McAlister GC, Nusinow DP, Jedrychowski MP, Wühr M, Huttlin EL, Erickson BK, Rad R, Haas W, Gygi SP. MultiNotch MS3 enables accurate, sensitive, and multiplexed detection of differential expression across cancer cell line proteomes. Analytical Chemistry. 86: 7150-8. PMID 24927332 DOI: 10.1021/Ac502040V  0.734
2012 Wühr M, Haas W, McAlister GC, Peshkin L, Rad R, Kirschner MW, Gygi SP. Accurate multiplexed proteomics at the MS2 level using the complement reporter ion cluster. Analytical Chemistry. 84: 9214-21. PMID 23098179 DOI: 10.1021/Ac301962S  0.634
2012 Mitchison T, Wühr M, Nguyen P, Ishihara K, Groen A, Field CM. Growth, interaction, and positioning of microtubule asters in extremely large vertebrate embryo cells. Cytoskeleton (Hoboken, N.J.). 69: 738-50. PMID 22786885 DOI: 10.1002/Cm.21050  0.78
2012 Nguyen PA, Ishihara K, Wühr M, Mitchison TJ. Pronuclear migration: no attachment? No union, but a futile cycle! Current Biology : Cb. 22: R409-11. PMID 22625860 DOI: 10.1016/J.Cub.2012.03.062  0.636
2011 Field CM, Wühr M, Anderson GA, Kueh HY, Strickland D, Mitchison TJ. Actin behavior in bulk cytoplasm is cell cycle regulated in early vertebrate embryos. Journal of Cell Science. 124: 2086-95. PMID 21610091 DOI: 10.1242/Dev.070102  0.769
2010 Wühr M, Tan ES, Parker SK, Detrich HW, Mitchison TJ. A model for cleavage plane determination in early amphibian and fish embryos. Current Biology : Cb. 20: 2040-5. PMID 21055946 DOI: 10.1016/J.Cub.2010.10.024  0.665
2009 Wühr M, Mitchison TJ, Field CM. Size and speed go hand in hand in cytokinesis. Cell. 137: 798-800. PMID 19490886 DOI: 10.1016/J.Cell.2009.05.012  0.728
2009 Wühr M, Dumont S, Groen AC, Needleman DJ, Mitchison TJ. How does a millimeter-sized cell find its center? Cell Cycle (Georgetown, Tex.). 8: 1115-21. PMID 19282671 DOI: 10.4161/Cc.8.8.8150  0.788
2008 Wühr M, Mitchison TJ, Field CM. Mitosis: new roles for myosin-X and actin at the spindle. Current Biology : Cb. 18: R912-4. PMID 18957236 DOI: 10.1016/J.Cub.2008.08.043  0.742
2008 Wühr M, Chen Y, Dumont S, Groen AC, Needleman DJ, Salic A, Mitchison TJ. Evidence for an upper limit to mitotic spindle length. Current Biology : Cb. 18: 1256-61. PMID 18718761 DOI: 10.1016/J.Cub.2008.07.092  0.764
2006 Gorr IH, Reis A, Boos D, Wühr M, Madgwick S, Jones KT, Stemmann O. Essential CDK1-inhibitory role for separase during meiosis I in vertebrate oocytes. Nature Cell Biology. 8: 1035-7. PMID 16906143 DOI: 10.1038/Ncb1467  0.336
2005 Franzmann TM, Wühr M, Richter K, Walter S, Buchner J. The activation mechanism of Hsp26 does not require dissociation of the oligomer. Journal of Molecular Biology. 350: 1083-93. PMID 15967461 DOI: 10.1016/J.Jmb.2005.05.034  0.313
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