Liangcai Gu, Ph.D. - Publications

Affiliations: 
2008 University of Michigan, Ann Arbor, Ann Arbor, MI 
Area:
cryptophycin anticancer drugs

18 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2015 Khare D, Hale WA, Tripathi A, Gu L, Sherman DH, Gerwick WH, Håkansson K, Smith JL. Structural Basis for Cyclopropanation by a Unique Enoyl-Acyl Carrier Protein Reductase. Structure (London, England : 1993). PMID 26526850 DOI: 10.1016/J.Str.2015.09.013  0.662
2015 Liu B, Xue Y, Zhao W, Chen Y, Fan C, Gu L, Zhang Y, Zhang X, Sun L, Huang X, Ding W, Sun F, Ji W, Xu T. Three-dimensional super-resolution protein localization correlated with vitrified cellular context. Scientific Reports. 5: 13017. PMID 26462878 DOI: 10.1038/Srep13017  0.394
2014 Li J, Gu L, Aach J, Church GM. Improved cell-free RNA and protein synthesis system. Plos One. 9: e106232. PMID 25180701 DOI: 10.1371/Journal.Pone.0106232  0.312
2012 Gehret JJ, Gu L, Geders TW, Brown WC, Gerwick L, Gerwick WH, Sherman DH, Smith JL. Structure and activity of DmmA, a marine haloalkane dehalogenase. Protein Science : a Publication of the Protein Society. 21: 239-48. PMID 22124946 DOI: 10.1002/Pro.2009  0.506
2012 Busche A, Gottstein D, Hein C, Ripin N, Pader I, Tufar P, Eisman EB, Gu L, Walsh CT, Sherman DH, Löhr F, Güntert P, Dötsch V. Characterization of molecular interactions between ACP and halogenase domains in the Curacin A polyketide synthase. Acs Chemical Biology. 7: 378-86. PMID 22103656 DOI: 10.1021/Cb200352Q  0.557
2011 Gu L, Eisman EB, Dutta S, Franzmann TM, Walter S, Gerwick WH, Skiniotis G, Sherman DH. Tandem acyl carrier proteins in the curacin biosynthetic pathway promote consecutive multienzyme reactions with a synergistic effect. Angewandte Chemie (International Ed. in English). 50: 2795-8. PMID 21387490 DOI: 10.1002/Anie.201005280  0.494
2011 Gehret JJ, Gu L, Gerwick WH, Wipf P, Sherman DH, Smith JL. Terminal alkene formation by the thioesterase of curacin A biosynthesis: structure of a decarboxylating thioesterase. The Journal of Biological Chemistry. 286: 14445-54. PMID 21357626 DOI: 10.1074/Jbc.M110.214635  0.556
2010 Khare D, Wang B, Gu L, Razelun J, Sherman DH, Gerwick WH, HÃ¥kansson K, Smith JL. Conformational switch triggered by alpha-ketoglutarate in a halogenase of curacin A biosynthesis. Proceedings of the National Academy of Sciences of the United States of America. 107: 14099-104. PMID 20660778 DOI: 10.1073/Pnas.1006738107  0.556
2009 Gu L, Wang B, Kulkarni A, Gehret JJ, Lloyd KR, Gerwick L, Gerwick WH, Wipf P, HÃ¥kansson K, Smith JL, Sherman DH. Polyketide decarboxylative chain termination preceded by o-sulfonation in curacin a biosynthesis. Journal of the American Chemical Society. 131: 16033-5. PMID 19835378 DOI: 10.1021/Ja9071578  0.546
2009 Gu L, Wang B, Kulkarni A, Geders TW, Grindberg RV, Gerwick L, HÃ¥kansson K, Wipf P, Smith JL, Gerwick WH, Sherman DH. Metamorphic enzyme assembly in polyketide diversification. Nature. 459: 731-5. PMID 19494914 DOI: 10.1038/Nature07870  0.533
2009 Jones AC, Gu L, Sorrels CM, Sherman DH, Gerwick WH. New tricks from ancient algae: natural products biosynthesis in marine cyanobacteria. Current Opinion in Chemical Biology. 13: 216-23. PMID 19307147 DOI: 10.1016/J.Cbpa.2009.02.019  0.503
2009 Sharp K, Arthur KE, Gu L, Ross C, Harrison G, Gunasekera SP, Meickle T, Matthew S, Luesch H, Thacker RW, Sherman DH, Paul VJ. Phylogenetic and chemical diversity of three chemotypes of bloom-forming lyngbya species (Cyanobacteria: Oscillatoriales) from reefs of southeastern Florida. Applied and Environmental Microbiology. 75: 2879-88. PMID 19270119 DOI: 10.1128/Aem.02656-08  0.459
2009 Gu L, Wang B, Sherman D, Håkansson K. IRMPD-based quantification of ER-catalyzed saturation and cyclopropanation reactions Nature Protocols. DOI: 10.1038/Nprot.2009.131  0.489
2007 Gu L, Geders TW, Wang B, Gerwick WH, Håkansson K, Smith JL, Sherman DH. GNAT-like strategy for polyketide chain initiation. Science (New York, N.Y.). 318: 970-4. PMID 17991863 DOI: 10.1126/Science.1148790  0.522
2007 Geders TW, Gu L, Mowers JC, Liu H, Gerwick WH, Håkansson K, Sherman DH, Smith JL. Crystal structure of the ECH2 catalytic domain of CurF from Lyngbya majuscula. Insights into a decarboxylase involved in polyketide chain beta-branching. The Journal of Biological Chemistry. 282: 35954-63. PMID 17928301 DOI: 10.1074/Jbc.M703921200  0.589
2006 Gu L, Jia J, Liu H, Håkansson K, Gerwick WH, Sherman DH. Metabolic coupling of dehydration and decarboxylation in the curacin A pathway: functional identification of a mechanistically diverse enzyme pair. Journal of the American Chemical Society. 128: 9014-5. PMID 16834357 DOI: 10.1021/Ja0626382  0.547
2003 Abulimiti A, Fu X, Gu L, Feng X, Chang Z. Mycobacterium tuberculosis Hsp16.3 nonamers are assembled and re-assembled via trimer and hexamer intermediates. Journal of Molecular Biology. 326: 1013-23. PMID 12589750 DOI: 10.1016/S0022-2836(03)00018-4  0.32
2002 Gu L, Abulimiti A, Li W, Chang Z. Monodisperse Hsp16.3 nonamer exhibits dynamic dissociation and reassociation, with the nonamer dissociation prerequisite for chaperone-like activity. Journal of Molecular Biology. 319: 517-26. PMID 12051925 DOI: 10.1016/S0022-2836(02)00311-X  0.323
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