| Year |
Citation |
Score |
| 2016 |
Hilal T, Yamamoto H, Loerke J, Bürger J, Mielke T, Spahn CM. Structural insights into ribosomal rescue by Dom34 and Hbs1 at near-atomic resolution. Nature Communications. 7: 13521. PMID 27995908 DOI: 10.1038/ncomms13521 |
0.316 |
|
| 2016 |
Sprink T, Ramrath DJ, Yamamoto H, Yamamoto K, Loerke J, Ismer J, Hildebrand PW, Scheerer P, Bürger J, Mielke T, Spahn CM. Structures of ribosome-bound initiation factor 2 reveal the mechanism of subunit association. Science Advances. 2: e1501502. PMID 26973877 DOI: 10.1126/sciadv.1501502 |
0.381 |
|
| 2015 |
Yamamoto H, Collier M, Loerke J, Ismer J, Schmidt A, Hilal T, Sprink T, Yamamoto K, Mielke T, Bürger J, Shaikh TR, Dabrowski M, Hildebrand PW, Scheerer P, Spahn CM. Molecular architecture of the ribosome-bound Hepatitis C Virus internal ribosomal entry site RNA. The Embo Journal. PMID 26604301 DOI: 10.15252/embj.201592469 |
0.357 |
|
| 2015 |
Muhs M, Hilal T, Mielke T, Skabkin MA, Sanbonmatsu KY, Pestova TV, Spahn CM. Cryo-EM of ribosomal 80S complexes with termination factors reveals the translocated cricket paralysis virus IRES. Molecular Cell. 57: 422-32. PMID 25601755 DOI: 10.1016/J.Molcel.2014.12.016 |
0.367 |
|
| 2014 |
Yamamoto H, Unbehaun A, Loerke J, Behrmann E, Collier M, Bürger J, Mielke T, Spahn CM. Structure of the mammalian 80S initiation complex with initiation factor 5B on HCV-IRES RNA. Nature Structural & Molecular Biology. 21: 721-7. PMID 25064512 DOI: 10.1038/nsmb.2859 |
0.333 |
|
| 2014 |
Budkevich TV, Giesebrecht J, Behrmann E, Loerke J, Ramrath DJ, Mielke T, Ismer J, Hildebrand PW, Tung CS, Nierhaus KH, Sanbonmatsu KY, Spahn CM. Regulation of the mammalian elongation cycle by subunit rolling: a eukaryotic-specific ribosome rearrangement. Cell. 158: 121-31. PMID 24995983 DOI: 10.1016/J.Cell.2014.04.044 |
0.356 |
|
| 2014 |
Ban N, Beckmann R, Cate JH, Dinman JD, Dragon F, Ellis SR, Lafontaine DL, Lindahl L, Liljas A, Lipton JM, McAlear MA, Moore PB, Noller HF, Ortega J, Panse VG, ... ... Spahn CM, et al. A new system for naming ribosomal proteins. Current Opinion in Structural Biology. 24: 165-9. PMID 24524803 DOI: 10.1016/J.Sbi.2014.01.002 |
0.348 |
|
| 2014 |
Yamamoto H, Qin Y, Achenbach J, Li C, Kijek J, Spahn CM, Nierhaus KH. EF-G and EF4: translocation and back-translocation on the bacterial ribosome. Nature Reviews. Microbiology. 12: 89-100. PMID 24362468 DOI: 10.1038/Nrmicro3176 |
0.393 |
|
| 2013 |
Ramrath DJ, Lancaster L, Sprink T, Mielke T, Loerke J, Noller HF, Spahn CM. Visualization of two transfer RNAs trapped in transit during elongation factor G-mediated translocation. Proceedings of the National Academy of Sciences of the United States of America. 110: 20964-9. PMID 24324168 DOI: 10.1073/Pnas.1320387110 |
0.368 |
|
| 2012 |
Ramrath DJ, Yamamoto H, Rother K, Wittek D, Pech M, Mielke T, Loerke J, Scheerer P, Ivanov P, Teraoka Y, Shpanchenko O, Nierhaus KH, Spahn CM. The complex of tmRNA-SmpB and EF-G on translocating ribosomes. Nature. 485: 526-9. PMID 22622583 DOI: 10.1038/nature11006 |
0.403 |
|
| 2011 |
Budkevich T, Giesebrecht J, Altman RB, Munro JB, Mielke T, Nierhaus KH, Blanchard SC, Spahn CM. Structure and dynamics of the mammalian ribosomal pretranslocation complex. Molecular Cell. 44: 214-24. PMID 22017870 DOI: 10.1016/J.Molcel.2011.07.040 |
0.383 |
|
| 2011 |
Muhs M, Yamamoto H, Ismer J, Takaku H, Nashimoto M, Uchiumi T, Nakashima N, Mielke T, Hildebrand PW, Nierhaus KH, Spahn CM. Structural basis for the binding of IRES RNAs to the head of the ribosomal 40S subunit. Nucleic Acids Research. 39: 5264-75. PMID 21378123 DOI: 10.1093/nar/gkr114 |
0.358 |
|
| 2010 |
Ratje AH, Loerke J, Mikolajka A, Brünner M, Hildebrand PW, Starosta AL, Dönhöfer A, Connell SR, Fucini P, Mielke T, Whitford PC, Onuchic JN, Yu Y, Sanbonmatsu KY, Hartmann RK, ... ... Spahn CM, et al. Head swivel on the ribosome facilitates translocation by means of intra-subunit tRNA hybrid sites. Nature. 468: 713-6. PMID 21124459 DOI: 10.1038/Nature09547 |
0.379 |
|
| 2010 |
Loerke J, Giesebrecht J, Spahn CM. Multiparticle cryo-EM of ribosomes. Methods in Enzymology. 483: 161-77. PMID 20888474 DOI: 10.1016/S0076-6879(10)83008-3 |
0.341 |
|
| 2009 |
Schuette JC, Murphy FV, Kelley AC, Weir JR, Giesebrecht J, Connell SR, Loerke J, Mielke T, Zhang W, Penczek PA, Ramakrishnan V, Spahn CM. GTPase activation of elongation factor EF-Tu by the ribosome during decoding. The Embo Journal. 28: 755-65. PMID 19229291 DOI: 10.1038/emboj.2009.26 |
0.354 |
|
| 2008 |
Connell SR, Topf M, Qin Y, Wilson DN, Mielke T, Fucini P, Nierhaus KH, Spahn CM. A new tRNA intermediate revealed on the ribosome during EF4-mediated back-translocation. Nature Structural & Molecular Biology. 15: 910-5. PMID 19172743 DOI: 10.1038/Nsmb.1469 |
0.363 |
|
| 2006 |
Schüler M, Connell SR, Lescoute A, Giesebrecht J, Dabrowski M, Schroeer B, Mielke T, Penczek PA, Westhof E, Spahn CM. Structure of the ribosome-bound cricket paralysis virus IRES RNA. Nature Structural & Molecular Biology. 13: 1092-6. PMID 17115051 DOI: 10.1038/nsmb1177 |
0.399 |
|
| 2006 |
Andersen CB, Becker T, Blau M, Anand M, Halic M, Balar B, Mielke T, Boesen T, Pedersen JS, Spahn CM, Kinzy TG, Andersen GR, Beckmann R. Structure of eEF3 and the mechanism of transfer RNA release from the E-site. Nature. 443: 663-8. PMID 16929303 DOI: 10.1038/Nature05126 |
0.367 |
|
| 2006 |
Penczek PA, Frank J, Spahn CM. A method of focused classification, based on the bootstrap 3D variance analysis, and its application to EF-G-dependent translocation. Journal of Structural Biology. 154: 184-94. PMID 16520062 DOI: 10.1016/J.Jsb.2005.12.013 |
0.495 |
|
| 2006 |
Penczek PA, Yang C, Frank J, Spahn CM. Estimation of variance in single-particle reconstruction using the bootstrap technique. Journal of Structural Biology. 154: 168-83. PMID 16510296 DOI: 10.1016/J.Jsb.2006.01.003 |
0.411 |
|
| 2005 |
Halic M, Becker T, Frank J, Spahn CM, Beckmann R. Localization and dynamic behavior of ribosomal protein L30e. Nature Structural & Molecular Biology. 12: 467-8. PMID 15864315 DOI: 10.1038/Nsmb933 |
0.491 |
|
| 2004 |
Sengupta J, Nilsson J, Gursky R, Spahn CM, Nissen P, Frank J. Identification of the versatile scaffold protein RACK1 on the eukaryotic ribosome by cryo-EM. Nature Structural & Molecular Biology. 11: 957-62. PMID 15334071 DOI: 10.1038/Nsmb822 |
0.461 |
|
| 2004 |
Spahn CM, Jan E, Mulder A, Grassucci RA, Sarnow P, Frank J. Cryo-EM visualization of a viral internal ribosome entry site bound to human ribosomes: the IRES functions as an RNA-based translation factor. Cell. 118: 465-75. PMID 15315759 DOI: 10.1016/J.Cell.2004.08.001 |
0.569 |
|
| 2004 |
Agrawal RK, Sharma MR, Kiel MC, Hirokawa G, Booth TM, Spahn CM, Grassucci RA, Kaji A, Frank J. Visualization of ribosome-recycling factor on the Escherichia coli 70S ribosome: functional implications. Proceedings of the National Academy of Sciences of the United States of America. 101: 8900-5. PMID 15178758 DOI: 10.1073/Pnas.0401904101 |
0.561 |
|
| 2004 |
Halic M, Becker T, Pool MR, Spahn CM, Grassucci RA, Frank J, Beckmann R. Structure of the signal recognition particle interacting with the elongation-arrested ribosome. Nature. 427: 808-14. PMID 14985753 DOI: 10.1038/Nature02342 |
0.484 |
|
| 2004 |
Spahn CM, Gomez-Lorenzo MG, Grassucci RA, Jørgensen R, Andersen GR, Beckmann R, Penczek PA, Ballesta JP, Frank J. Domain movements of elongation factor eEF2 and the eukaryotic 80S ribosome facilitate tRNA translocation. The Embo Journal. 23: 1008-19. PMID 14976550 DOI: 10.1038/Sj.Emboj.7600102 |
0.543 |
|
| 2003 |
Moccia R, Chen D, Lyles V, Kapuya E, E Y, Kalachikov S, Spahn CM, Frank J, Kandel ER, Barad M, Martin KC. An unbiased cDNA library prepared from isolated Aplysia sensory neuron processes is enriched for cytoskeletal and translational mRNAs. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 23: 9409-17. PMID 14561869 DOI: 10.1523/Jneurosci.23-28-09409.2003 |
0.419 |
|
| 2002 |
Gao H, Spahn CM, Grassucci RA, Frank J. An assay for local quality in cryo-electron micrographs of single particles. Ultramicroscopy. 93: 169-78. PMID 12425594 DOI: 10.1016/S0304-3991(02)00157-2 |
0.442 |
|
| 2002 |
Schäfer MA, Tastan AO, Patzke S, Blaha G, Spahn CM, Wilson DN, Nierhaus KH. Codon-anticodon interaction at the P site is a prerequisite for tRNA interaction with the small ribosomal subunit. The Journal of Biological Chemistry. 277: 19095-105. PMID 11867615 DOI: 10.1074/jbc.M108902200 |
0.308 |
|
| 2001 |
Beckmann R, Spahn CM, Frank J, Blobel G. The active 80S ribosome-Sec61 complex. Cold Spring Harbor Symposia On Quantitative Biology. 66: 543-54. PMID 12762056 DOI: 10.1101/Sqb.2001.66.543 |
0.424 |
|
| 2001 |
Spahn CM, Beckmann R, Eswar N, Penczek PA, Sali A, Blobel G, Frank J. Structure of the 80S ribosome from Saccharomyces cerevisiae--tRNA-ribosome and subunit-subunit interactions. Cell. 107: 373-86. PMID 11701127 DOI: 10.1016/S0092-8674(01)00539-6 |
0.6 |
|
| 2001 |
Beckmann R, Spahn CM, Eswar N, Helmers J, Penczek PA, Sali A, Frank J, Blobel G. Architecture of the protein-conducting channel associated with the translating 80S ribosome. Cell. 107: 361-72. PMID 11701126 DOI: 10.1016/S0092-8674(01)00541-4 |
0.57 |
|
| 2001 |
Spahn CM, Blaha G, Agrawal RK, Penczek P, Grassucci RA, Trieber CA, Connell SR, Taylor DE, Nierhaus KH, Frank J. Localization of the ribosomal protection protein Tet(O) on the ribosome and the mechanism of tetracycline resistance. Molecular Cell. 7: 1037-45. PMID 11389850 DOI: 10.1016/S1097-2765(01)00238-6 |
0.53 |
|
| 2001 |
Spahn CM, Kieft JS, Grassucci RA, Penczek PA, Zhou K, Doudna JA, Frank J. Hepatitis C virus IRES RNA-induced changes in the conformation of the 40s ribosomal subunit. Science (New York, N.Y.). 291: 1959-62. PMID 11239155 DOI: 10.1126/Science.1058409 |
0.553 |
|
| 2000 |
Diedrich G, Spahn CM, Stelzl U, Schäfer MA, Wooten T, Bochkariov DE, Cooperman BS, Traut RR, Nierhaus KH. Ribosomal protein L2 is involved in the association of the ribosomal subunits, tRNA binding to A and P sites and peptidyl transfer. The Embo Journal. 19: 5241-50. PMID 11013226 DOI: 10.1093/Emboj/19.19.5241 |
0.362 |
|
| 2000 |
Spahn CM, Penczek PA, Leith A, Frank J. A method for differentiating proteins from nucleic acids in intermediate-resolution density maps: cryo-electron microscopy defines the quaternary structure of the Escherichia coli 70S ribosome. Structure (London, England : 1993). 8: 937-48. PMID 10986461 DOI: 10.1016/S0969-2126(00)00185-4 |
0.523 |
|
| 2000 |
Agrawal RK, Spahn CM, Penczek P, Grassucci RA, Nierhaus KH, Frank J. Visualization of tRNA movements on the Escherichia coli 70S ribosome during the elongation cycle. The Journal of Cell Biology. 150: 447-60. PMID 10931859 DOI: 10.1083/Jcb.150.3.447 |
0.526 |
|
| 2000 |
Gomez-Lorenzo MG, Spahn CM, Agrawal RK, Grassucci RA, Penczek P, Chakraburtty K, Ballesta JP, Lavandera JL, Garcia-Bustos JF, Frank J. Three-dimensional cryo-electron microscopy localization of EF2 in the Saccharomyces cerevisiae 80S ribosome at 17.5 A resolution. The Embo Journal. 19: 2710-8. PMID 10835368 DOI: 10.1093/Emboj/19.11.2710 |
0.521 |
|
| 2000 |
Blaha G, Stelzl U, Spahn CM, Agrawal RK, Frank J, Nierhaus KH. Preparation of functional ribosomal complexes and effect of buffer conditions on tRNA positions observed by cryoelectron microscopy. Methods in Enzymology. 317: 292-309. PMID 10829287 DOI: 10.1016/S0076-6879(00)17021-1 |
0.548 |
|
| 2000 |
Stelzl U, Spahn CM, Nierhaus KH. Selecting rRNA binding sites for the ribosomal proteins L4 and L6 from randomly fragmented rRNA: application of a method called SERF. Proceedings of the National Academy of Sciences of the United States of America. 97: 4597-602. PMID 10781065 DOI: 10.1073/pnas.090009297 |
0.316 |
|
| 2000 |
Gabashvili IS, Agrawal RK, Spahn CM, Grassucci RA, Svergun DI, Frank J, Penczek P. Solution structure of the E. coli 70S ribosome at 11.5 A resolution. Cell. 100: 537-49. PMID 10721991 DOI: 10.1016/S0092-8674(00)80690-X |
0.587 |
|
| 1999 |
Spahn CM, Grassucci RA, Penczek P, Frank J. Direct three-dimensional localization and positive identification of RNA helices within the ribosome by means of genetic tagging and cryo-electron microscopy. Structure (London, England : 1993). 7: 1567-73. PMID 10647187 DOI: 10.1016/S0969-2126(00)88347-1 |
0.494 |
|
| 1998 |
Spahn CM, Nierhaus KH. Models of the elongation cycle: an evaluation. Biological Chemistry. 379: 753-72. PMID 9705140 DOI: 10.1515/Bchm.1998.379.7.753 |
0.368 |
|
| 1996 |
Dabrowski M, Junemann R, Schafer MA, Spahn CM, Nierhaus KH, Alekseeva EV, Dontsova OA, Shpanchenko OV, Bogdanov AA. [Phosphate sites of RNA-ligands interacting with ribosome at different stages of translation. Thiophosphate method of analysis]. Biokhimiií¡a (Moscow, Russia). 61: 1971-83. PMID 9004858 |
0.325 |
|
| 1995 |
Nierhaus KH, Beyer D, Dabrowski M, Schäfer MA, Spahn CM, Wadzack J, Bittner JU, Burkhardt N, Diedrich G, Jünemann R. The elongating ribosome: structural and functional aspects. Biochemistry and Cell Biology = Biochimie Et Biologie Cellulaire. 73: 1011-21. PMID 8722016 |
0.354 |
|
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