Petr Svoboda, Ph.D. - Publications

Affiliations: 
2002 University of Pennsylvania, Philadelphia, PA, United States 
Area:
Developmental Biology

77 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Zapletal D, Kubicek K, Svoboda P, Stefl R. Dicer structure and function: conserved and evolving features. Embo Reports. 24: e57215. PMID 37310138 DOI: 10.15252/embr.202357215  0.322
2021 Malik R, Svoboda P. CRISPR-Induced Expression of N-Terminally Truncated Dicer in Mouse Cells. Genes. 12. PMID 33918028 DOI: 10.3390/genes12040540  0.402
2020 Svoboda P. Key Mechanistic Principles and Considerations Concerning RNA Interference. Frontiers in Plant Science. 11: 1237. PMID 32903622 DOI: 10.3389/fpls.2020.01237  0.321
2020 Kataruka S, Modrak M, Kinterova V, Malik R, Zeitler DM, Horvat F, Kanka J, Meister G, Svoboda P. MicroRNA dilution during oocyte growth disables the microRNA pathway in mammalian oocytes. Nucleic Acids Research. PMID 32609824 DOI: 10.1093/Nar/Gkaa543  0.322
2020 Ganesh S, Horvat F, Drutovic D, Efenberkova M, Pinkas D, Jindrova A, Pasulka J, Iyyappan R, Malik R, Susor A, Vlahovicek K, Solc P, Svoboda P. The most abundant maternal lncRNA Sirena1 acts post-transcriptionally and impacts mitochondrial distribution. Nucleic Acids Research. PMID 31956907 DOI: 10.1093/Nar/Gkz1239  0.481
2019 Taborska E, Pasulka J, Malik R, Horvat F, Jenickova I, Jelić Matošević Z, Svoboda P. Restricted and non-essential redundancy of RNAi and piRNA pathways in mouse oocytes. Plos Genetics. 15: e1008261. PMID 31860668 DOI: 10.1371/Journal.Pgen.1008261  0.453
2019 Demeter T, Vaskovicova M, Malik R, Horvat F, Pasulka J, Svobodova E, Flemr M, Svoboda P. Main constraints for RNAi induced by expressed long dsRNA in mouse cells. Life Science Alliance. 2. PMID 30808654 DOI: 10.26508/lsa.201800289  0.307
2018 Horvat F, Fulka H, Jankele R, Malik R, Jun M, Solcova K, Sedlacek R, Vlahovicek K, Schultz RM, Svoboda P. Role of in maternal mRNA turnover. Life Science Alliance. 1: e201800084. PMID 30456367 DOI: 10.26508/lsa.201800084  0.538
2018 Cechova K, Hlouskova M, Javorkova E, Roubalova L, Ujcikova H, Holan V, Svoboda P. Up-regulation of μ-, δ- and κ-opioid receptors in concanavalin A-stimulated rat spleen lymphocytes. Journal of Neuroimmunology. 321: 12-23. PMID 29957382 DOI: 10.1016/J.Jneuroim.2018.05.008  0.308
2018 Schultz RM, Stein P, Svoboda P. The oocyte-to-embryo transition in mouse: past, present, and future. Biology of Reproduction. PMID 29462259 DOI: 10.1093/Biolre/Ioy013  0.567
2017 Svoboda P. Mammalian zygotic genome activation. Seminars in Cell & Developmental Biology. PMID 29233752 DOI: 10.1016/J.Semcdb.2017.12.006  0.42
2017 Svoboda P. Long and small noncoding RNAs during oocyte-to-embryo transition in mammals. Biochemical Society Transactions. PMID 28939692 DOI: 10.1042/Bst20170033  0.49
2017 Franke V, Ganesh S, Karlic R, Malik R, Pasulka J, Horvat F, Kuzman M, Fulka H, Cernohorska M, Urbanova J, Svobodova E, Ma J, Suzuki Y, Aoki F, Schultz RM, ... ... Svoboda P, et al. Long terminal repeats power evolution of genes and gene expression programs in mammalian oocytes and zygotes. Genome Research. PMID 28522611 DOI: 10.1101/Gr.216150.116  0.575
2017 Karlic R, Ganesh S, Franke V, Svobodova E, Urbanova J, Suzuki Y, Aoki F, Vlahovicek K, Svoboda P. Long non-coding RNA exchange during the oocyte-to-embryo transition in mice. Dna Research : An International Journal For Rapid Publication of Reports On Genes and Genomes. PMID 28087610 DOI: 10.1093/Dnares/Dsw058  0.485
2017 Svoboda P, Fulka H, Malik R. Clearance of Parental Products. Advances in Experimental Medicine and Biology. 953: 489-535. PMID 27975278 DOI: 10.1007/978-3-319-46095-6_10  0.32
2016 Svobodova E, Kubikova J, Svoboda P. Production of small RNAs by mammalian Dicer. Pflugers Archiv : European Journal of Physiology. PMID 27048428 DOI: 10.1007/S00424-016-1817-6  0.42
2016 Ganesh S, Svoboda P. Retrotransposon-associated long non-coding RNAs in mice and men. Pflugers Archiv : European Journal of Physiology. PMID 27044413 DOI: 10.1007/S00424-016-1818-5  0.366
2015 Svoboda P, Franke V, Schultz RM. Sculpting the Transcriptome During the Oocyte-to-Embryo Transition in Mouse. Current Topics in Developmental Biology. 113: 305-49. PMID 26358877 DOI: 10.1016/Bs.Ctdb.2015.06.004  0.649
2015 Abe K, Yamamoto R, Franke V, Cao M, Suzuki Y, Suzuki MG, Vlahovicek K, Svoboda P, Schultz RM, Aoki F. The first murine zygotic transcription is promiscuous and uncoupled from splicing and 3' processing. The Embo Journal. 34: 1523-37. PMID 25896510 DOI: 10.15252/Embj.201490648  0.606
2015 Svoboda P, Franke V, Schultz RM. Sculpting the Transcriptome During the Oocyte-to-Embryo Transition in Mouse Current Topics in Developmental Biology. DOI: 10.1016/bs.ctdb.2015.06.004  0.46
2014 Abranches E, Guedes AM, Moravec M, Maamar H, Svoboda P, Raj A, Henrique D. Stochastic NANOG fluctuations allow mouse embryonic stem cells to explore pluripotency. Development (Cambridge, England). 141: 2770-9. PMID 25005472 DOI: 10.1242/Dev.108910  0.309
2014 Jankele R, Svoboda P. TAL effectors: tools for DNA targeting. Briefings in Functional Genomics. 13: 409-19. PMID 24907364 DOI: 10.1093/Bfgp/Elu013  0.32
2014 Svoboda P. Renaissance of mammalian endogenous RNAi. Febs Letters. 588: 2550-6. PMID 24873877 DOI: 10.1016/J.Febslet.2014.05.030  0.458
2014 Flemr M, Moravec M, Libova V, Sedlacek R, Svoboda P. Lin28a is dormant, functional, and dispensable during mouse oocyte-to-embryo transition. Biology of Reproduction. 90: 131. PMID 24829024 DOI: 10.1095/Biolreprod.114.118703  0.493
2014 Chalupnikova K, Solc P, Sulimenko V, Sedlacek R, Svoboda P. An oocyte-specific ELAVL2 isoform is a translational repressor ablated from meiotically competent antral oocytes. Cell Cycle (Georgetown, Tex.). 13: 1187-200. PMID 24553115 DOI: 10.4161/Cc.28107  0.402
2014 Nejepinska J, Malik R, Wagner S, Svoboda P. Reporters transiently transfected into mammalian cells are highly sensitive to translational repression induced by dsRNA expression. Plos One. 9: e87517. PMID 24475301 DOI: 10.1371/Journal.Pone.0087517  0.45
2014 Podolska K, Sedlak D, Bartunek P, Svoboda P. Fluorescence-based high-throughput screening of dicer cleavage activity. Journal of Biomolecular Screening. 19: 417-26. PMID 23945873 DOI: 10.1177/1087057113497400  0.381
2013 Flemr M, Malik R, Franke V, Nejepinska J, Sedlacek R, Vlahovicek K, Svoboda P. A retrotransposon-driven dicer isoform directs endogenous small interfering RNA production in mouse oocytes. Cell. 155: 807-16. PMID 24209619 DOI: 10.1016/J.Cell.2013.10.001  0.439
2013 Stein P, Svoboda P, Schultz RM. RNAi-based methods for gene silencing in mouse oocytes. Methods in Molecular Biology (Clifton, N.J.). 957: 135-51. PMID 23138949 DOI: 10.1007/978-1-62703-191-2_9  0.616
2013 Ma J, Flemr M, Strnad H, Svoboda P, Schultz RM. Maternally recruited DCP1A and DCP2 contribute to messenger RNA degradation during oocyte maturation and genome activation in mouse. Biology of Reproduction. 88: 11. PMID 23136299 DOI: 10.1095/Biolreprod.112.105312  0.601
2013 Chalupnikova K, Nejepinska J, Svoboda P. Production and application of long dsRNA in mammalian cells. Methods in Molecular Biology (Clifton, N.J.). 942: 291-314. PMID 23027058 DOI: 10.1007/978-1-62703-119-6_16  0.461
2012 Malik R, Svoboda P. Transgenic RNAi in mouse oocytes: the first decade. Animal Reproduction Science. 134: 64-8. PMID 22921723 DOI: 10.1016/J.Anireprosci.2012.08.012  0.494
2012 Nejepinska J, Malik R, Moravec M, Svoboda P. Deep sequencing reveals complex spurious transcription from transiently transfected plasmids. Plos One. 7: e43283. PMID 22916237 DOI: 10.1371/Journal.Pone.0043283  0.396
2012 Ohrt T, Muetze J, Svoboda P, Schwille P. Intracellular localization and routing of miRNA and RNAi pathway components. Current Topics in Medicinal Chemistry. 12: 79-88. PMID 22196276 DOI: 10.2174/156802612798919132  0.446
2012 Nejepinska J, Flemr M, Svoboda P. Control of the interferon response in RNAi experiments. Methods in Molecular Biology (Clifton, N.J.). 820: 133-61. PMID 22131030 DOI: 10.1007/978-1-61779-439-1_9  0.338
2012 Nejepinska J, Malik R, Filkowski J, Flemr M, Filipowicz W, Svoboda P. dsRNA expression in the mouse elicits RNAi in oocytes and low adenosine deamination in somatic cells. Nucleic Acids Research. 40: 399-413. PMID 21908396 DOI: 10.1093/Nar/Gkr702  0.492
2011 Podolska K, Svoboda P. Targeting genes in living mammals by RNA interference. Briefings in Functional Genomics. 10: 238-47. PMID 21737416 DOI: 10.1093/Bfgp/Elr013  0.478
2011 Flemr M, Svoboda P. Ribonucleoprotein localization in mouse oocytes. Methods (San Diego, Calif.). 53: 136-41. PMID 20708690 DOI: 10.1016/J.Ymeth.2010.08.005  0.44
2010 Svoboda P. Why mouse oocytes and early embryos ignore miRNAs? Rna Biology. 7: 559-63. PMID 21037419 DOI: 10.4161/Rna.7.5.12940  0.425
2010 Sarnova L, Malik R, Sedlacek R, Svoboda P. Shortcomings of short hairpin RNA-based transgenic RNA interference in mouse oocytes. Journal of Negative Results in Biomedicine. 9: 8. PMID 20939886 DOI: 10.1186/1477-5751-9-8  0.46
2010 Sinkkonen L, Hugenschmidt T, Filipowicz W, Svoboda P. Dicer is associated with ribosomal DNA chromatin in mammalian cells. Plos One. 5: e12175. PMID 20730047 DOI: 10.1371/Journal.Pone.0012175  0.472
2010 Svoboda P, Flemr M. The role of miRNAs and endogenous siRNAs in maternal-to-zygotic reprogramming and the establishment of pluripotency. Embo Reports. 11: 590-7. PMID 20651740 DOI: 10.1038/Embor.2010.102  0.434
2010 Ma J, Flemr M, Stein P, Berninger P, Malik R, Zavolan M, Svoboda P, Schultz RM. MicroRNA Activity Is Suppressed in Mouse Oocytes Current Biology. 20: 265-270. PMID 20116252 DOI: 10.1016/J.Cub.2009.12.042  0.565
2010 Flemr M, Ma J, Schultz RM, Svoboda P. P-body loss is concomitant with formation of a messenger RNA storage domain in mouse oocytes Biology of Reproduction. 82: 1008-1017. PMID 20075394 DOI: 10.1095/Biolreprod.109.082057  0.591
2010 Ma J, Flemr M, Medvedev S, Svoboda P, Schultz RM. Role of Maturation-Associated Recruitment of Dcp1a and Dcp2 in Degradation of Maternal mRNA. Biology of Reproduction. 83: 72-72. DOI: 10.1093/Biolreprod/83.S1.72  0.513
2009 Svoboda P, Stein P. RNAi experiments in mouse oocytes and early embryos. Cold Spring Harbor Protocols. 2009: pdb.top56. PMID 20147032 DOI: 10.1101/Pdb.Top56  0.471
2009 Svoboda P. Cloning a transgene for transgenic RNAi in mouse oocytes. Cold Spring Harbor Protocols. 2009: pdb.prot5134. PMID 20147029 DOI: 10.1101/Pdb.Prot5134  0.381
2009 Svoboda P. Preparation of dsRNA for microinjection experiments in mouse. Cold Spring Harbor Protocols. 2009: pdb.prot5131. PMID 20147026 DOI: 10.1101/Pdb.Prot5131  0.453
2009 Svoboda P. Cloning and sequencing an inverted repeat. Cold Spring Harbor Protocols. 2009: pdb.ip64. PMID 20147011 DOI: 10.1101/Pdb.Ip64  0.309
2009 Svoboda P. Choosing the sequence of dsRNA for RNAi in mouse. Cold Spring Harbor Protocols. 2009: pdb.ip63. PMID 20147010 DOI: 10.1101/Pdb.Ip63  0.414
2009 Ma J, Flemr M, Buffone M, Stein P, Svoboda P, Schultz R. Cytoplasmic Processing Body (P-body) Formation and miRNA Function in Mouse Oocytes. Biology of Reproduction. 81: 27-27. DOI: 10.1093/Biolreprod/81.S1.27  0.473
2008 Kutter C, Svoboda P. miRNA, siRNA, piRNA: Knowns of the unknown. Rna Biology. 5: 181-8. PMID 19182524 DOI: 10.4161/Rna.7227  0.473
2008 Sinkkonen L, Hugenschmidt T, Berninger P, Gaidatzis D, Mohn F, Artus-Revel CG, Zavolan M, Svoboda P, Filipowicz W. MicroRNAs control de novo DNA methylation through regulation of transcriptional repressors in mouse embryonic stem cells. Nature Structural & Molecular Biology. 15: 259-67. PMID 18311153 DOI: 10.1038/Nsmb.1391  0.311
2008 Svoboda P. RNA silencing in mammalian oocytes and early embryos. Current Topics in Microbiology and Immunology. 320: 225-56. PMID 18268847 DOI: 10.1007/978-3-540-75157-1_11  0.473
2006 Stein P, Svoboda P. RNA Isolation and RT-PCR from dsRNA-Treated Mouse Oocytes and Early Embryos. Csh Protocols. 2006. PMID 22485881 DOI: 10.1101/Pdb.Prot4513  0.438
2006 Stein P, Svoboda P. Microinjection of dsRNA into Mouse Oocytes and Early Embryos. Csh Protocols. 2006. PMID 22485879 DOI: 10.1101/Pdb.Prot4511  0.36
2006 Stein P, Svoboda P. Collection of Early Mouse Embryos for RNAi. Csh Protocols. 2006. PMID 22485878 DOI: 10.1101/Pdb.Prot4510  0.357
2006 Stein P, Svoboda P. Collection of Mouse Oocytes for RNAi. Csh Protocols. 2006. PMID 22485877 DOI: 10.1101/Pdb.Prot4509  0.383
2006 Stein P, Svoboda P. Preparation of dsRNA Molecules for RNAi in Mouse Oocytes and Early Embryos. Csh Protocols. 2006. PMID 22485876 DOI: 10.1101/Pdb.Prot4508  0.35
2006 Schmitter D, Filkowski J, Sewer A, Pillai RS, Oakeley EJ, Zavolan M, Svoboda P, Filipowicz W. Effects of Dicer and Argonaute down-regulation on mRNA levels in human HEK293 cells. Nucleic Acids Research. 34: 4801-15. PMID 16971455 DOI: 10.1093/Nar/Gkl646  0.443
2006 Horman SR, Svoboda P, Luning Prak ET. The potential regulation of L1 mobility by RNA interference. Journal of Biomedicine & Biotechnology. 2006: 32713. PMID 16877813 DOI: 10.1155/Jbb/2006/32713  0.308
2006 Bultman SJ, Gebuhr TC, Pan H, Svoboda P, Schultz RM, Magnuson T. Maternal BRG1 regulates zygotic genome activation in the mouse. Genes & Development. 20: 1744-54. PMID 16818606 DOI: 10.1101/Gad.1435106  0.623
2006 Puschendorf M, Stein P, Oakeley EJ, Schultz RM, Peters AH, Svoboda P. Abundant transcripts from retrotransposons are unstable in fully grown mouse oocytes. Biochemical and Biophysical Research Communications. 347: 36-43. PMID 16815300 DOI: 10.1016/J.Bbrc.2006.06.106  0.59
2006 Svoboda P, Cara AD. Hairpin RNA: a secondary structure of primary importance Cellular and Molecular Life Sciences. 63: 901-908. PMID 16568238 DOI: 10.1007/S00018-005-5558-5  0.442
2004 Gangloff YG, Mueller M, Dann SG, Svoboda P, Sticker M, Spetz JF, Um SH, Brown EJ, Cereghini S, Thomas G, Kozma SC. Disruption of the mouse mTOR gene leads to early postimplantation lethality and prohibits embryonic stem cell development. Molecular and Cellular Biology. 24: 9508-16. PMID 15485918 DOI: 10.1128/Mcb.24.21.9508-9516.2004  0.354
2004 Svoboda P, Stein P, Filipowicz W, Schultz RM. Lack of homologous sequence-specific DNA methylation in response to stable dsRNA expression in mouse oocytes. Nucleic Acids Research. 32: 3601-6. PMID 15247344 DOI: 10.1093/Nar/Gkh697  0.582
2004 Svoboda P. Long dsRNA and silent genes strike back:RNAi in mouse oocytes and early embryos Cytogenetic and Genome Research. 105: 422-434. PMID 15237230 DOI: 10.1159/000078215  0.493
2004 Svoboda P, Stein P, Anger M, Bernstein E, Hannon GJ, Schultz RM. RNAi and expression of retrotransposons MuERV-L and IAP in preimplantation mouse embryos. Developmental Biology. 269: 276-85. PMID 15081373 DOI: 10.1016/J.Ydbio.2004.01.028  0.584
2004 Fedoriw AM, Stein P, Svoboda P, Schultz RM, Bartolomei MS. Transgenic RNAi reveals essential function for CTCF in H19 gene imprinting. Science (New York, N.Y.). 303: 238-40. PMID 14716017 DOI: 10.1126/Science.1090934  0.536
2003 Stein P, Svoboda P, Schultz RM. Transgenic RNAi in mouse oocytes: a simple and fast approach to study gene function. Developmental Biology. 256: 187-93. PMID 12654301 DOI: 10.1016/S0012-1606(02)00122-7  0.615
2003 Stein P, Svoboda P, Anger M, Schultz RM. RNAi: mammalian oocytes do it without RNA-dependent RNA polymerase. Rna (New York, N.Y.). 9: 187-92. PMID 12554861 DOI: 10.1261/Rna.2860603  0.619
2002 Stein P, Svoboda P, Stumpo DJ, Blackshear PJ, Lombard DB, Johnson B, Schultz RM. Analysis of the role of RecQ helicases in RNAi in mammals. Biochemical and Biophysical Research Communications. 291: 1119-22. PMID 11883931 DOI: 10.1006/Bbrc.2002.6578  0.606
2001 Svoboda P, Stein P, Schultz RM. RNAi in mouse oocytes and preimplantation embryos: effectiveness of hairpin dsRNA. Biochemical and Biophysical Research Communications. 287: 1099-104. PMID 11587535 DOI: 10.1006/Bbrc.2001.5707  0.625
2001 Ma J, Svoboda P, Schultz RM, Stein P. Regulation of zygotic gene activation in the preimplantation mouse embryo: global activation and repression of gene expression. Biology of Reproduction. 64: 1713-21. PMID 11369600 DOI: 10.1095/Biolreprod64.6.1713  0.57
2000 Svoboda P, Stein P, Hayashi H, Schultz RM. Selective reduction of dormant maternal mRNAs in mouse oocytes by RNA interference. Development (Cambridge, England). 127: 4147-56. PMID 10976047  0.546
1999 Schultz RM, Davis W, Stein P, Svoboda P. Reprogramming of gene expression during preimplantation development. The Journal of Experimental Zoology. 285: 276-82. PMID 10497327 DOI: 10.1002/(Sici)1097-010X(19991015)285:3<276::Aid-Jez11>3.0.Co;2-K  0.549
1999 Zavadil J, Svoboda P, Liang H, Kottickal LV, Nagarajan L. An antisense transcript to SMAD5 expressed in fetal and tumor tissues Biochemical and Biophysical Research Communications. 255: 668-672. PMID 10049768 DOI: 10.1006/Bbrc.1999.0256  0.329
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