Mihael Freamat, Ph.D. - Related publications

2007 University of New Hampshire, Durham, NH, United States 
GnRH, GnRH receptors; neuroendocrinology
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50 most relevant papers in past 60 days:
Year Citation  Score
2020 Ito-Harashima S, Matano M, Onishi K, Nomura T, Nakajima S, Ebata S, Shiizaki K, Kawanishi M, Yagi T. Construction of reporter gene assays using and mutant yeasts for enhanced detection of various sex steroids. Genes and Environment : the Official Journal of the Japanese Environmental Mutagen Society. 42: 20. PMID 32514322 DOI: 10.1186/s41021-020-00159-x   
2020 Germann AL, Reichert DE, Burbridge AB, Pierce SR, Evers AS, Steinbach JH, Akk G. Analysis of modulation of the ρ1 GABAA receptor by combinations of inhibitory and potentiating neurosteroids reveals shared and distinct binding sites. Molecular Pharmacology. PMID 32675382 DOI: 10.1124/mol.120.119842   
2020 Fischer JP, Els-Heindl S, Beck-Sickinger AG. Adrenomedullin - Current Perspective on a Peptide Hormone with Significant Therapeutic Potential. Peptides. 170347. PMID 32569606 DOI: 10.1016/j.peptides.2020.170347   
2020 Gross KS, Mermelstein PG. Estrogen receptor signaling through metabotropic glutamate receptors. Vitamins and Hormones. 114: 211-232. PMID 32723544 DOI: 10.1016/bs.vh.2020.06.003   
2020 Neale PA, Grimaldi M, Boulahtouf A, Leusch FDL, Balaguer P. Assessing species-specific differences for nuclear receptor activation for environmental water extracts. Water Research. 185: 116247. PMID 32758789 DOI: 10.1016/j.watres.2020.116247   
2020 Lillo A, Martínez-Pinilla E, Reyes-Resina I, Navarro G, Franco R. Adenosine A and A Receptors Are Able to Interact with Each Other. A Further Piece in the Puzzle of Adenosine Receptor-Mediated Signaling. International Journal of Molecular Sciences. 21. PMID 32709103 DOI: 10.3390/ijms21145070   
2020 Motawe ZY, Abdelmaboud SS, Cuevas J, Breslin JW. PRE-084 as a tool to uncover potential therapeutic applications for selective sigma-1 receptor activation. The International Journal of Biochemistry & Cell Biology. 126: 105803. PMID 32668330 DOI: 10.1016/j.biocel.2020.105803   
2020 Rumpret M, Drylewicz J, Ackermans LJE, Borghans JAM, Medzhitov R, Meyaard L. Functional categories of immune inhibitory receptors. Nature Reviews. Immunology. PMID 32612208 DOI: 10.1038/s41577-020-0352-z   
2020 Ache BW. Position Review: Functional Selectivity in Mammalian Olfactory Receptors. Chemical Senses. PMID 32598441 DOI: 10.1093/chemse/bjaa046   
2020 Yu Liao VW, Kusay AS, Balle T, Ahring PK. Heterologous expression of concatenated nicotine acetylcholine receptors: pros and cons of subunit concatenation and recommendations for construct designs. British Journal of Pharmacology. PMID 32627170 DOI: 10.1111/bph.15188   
2020 Yu X, Yi P, Hamilton RA, Shen H, Chen M, Foulds CE, Mancini MA, Ludtke SJ, Wang Z, O'Malley BW. Structural Insights of Transcriptionally Active, Full-Length Androgen Receptor Coactivator Complexes. Molecular Cell. PMID 32668201 DOI: 10.1016/j.molcel.2020.06.031   
2020 Cardoso JCR, Garcia MG, Power DM. Tracing the Origins of the Pituitary Adenylate-Cyclase Activating Polypeptide (PACAP). Frontiers in Neuroscience. 14: 366. PMID 32508559 DOI: 10.3389/fnins.2020.00366   
2020 Gutjahr A, Papagno L, Vernejoul F, Lioux T, Jospin F, Chanut B, Perouzel E, Rochereau N, Appay V, Verrier B, Paul S. New chimeric TLR7/NOD2 agonist is a potent adjuvant to induce mucosal immune responses. Ebiomedicine. 58: 102922. PMID 32739871 DOI: 10.1016/j.ebiom.2020.102922   
2020 Gutjahr A, Papagno L, Vernejoul F, Lioux T, Jospin F, Chanut B, Perouzel E, Rochereau N, Appay V, Verrier B, Paul S. New chimeric TLR7/NOD2 agonist is a potent adjuvant to induce mucosal immune responses. Ebiomedicine. 58: 102922. PMID 32739871 DOI: 10.1016/j.ebiom.2020.102922   
2020 Magno AL, Leatherbarrow KM, Brown SJ, Wilson SG, Walsh JP, Ward BK. Functional Analysis of Calcium-Sensing Receptor Variants Identified in Families Provisionally Diagnosed with Familial Hypocalciuric Hypercalcaemia. Calcified Tissue International. PMID 32638038 DOI: 10.1007/s00223-020-00715-1   
2020 Bondarev AD, Attwood MM, Jonsson J, Chubarev VN, Tarasov VV, Schiöth HB. Opportunities and challenges for drug discovery in modulating Adhesion G protein-coupled receptor (GPCR) functions. Expert Opinion On Drug Discovery. 1-17. PMID 32648789 DOI: 10.1080/17460441.2020.1791075   
2020 Kumar A, Foster TC. G Protein-Coupled Estrogen Receptor: Rapid Effects on Hippocampal-Dependent Spatial Memory and Synaptic Plasticity. Frontiers in Endocrinology. 11: 385. PMID 32587576 DOI: 10.3389/fendo.2020.00385   
2020 Kim HR, Xu J, Maeda S, Duc NM, Ahn D, Du Y, Chung KY. Structural mechanism underlying primary and secondary coupling between GPCRs and the Gi/o family. Nature Communications. 11: 3160. PMID 32572026 DOI: 10.1038/s41467-020-16975-2   
2020 Tasma Z, Wills P, Hay DL, Walker CS. Agonist bias and agonist-dependent antagonism at corticotrophin releasing factor receptors. Pharmacology Research & Perspectives. 8: e00595. PMID 32529807 DOI: 10.1002/prp2.595   
2020 Li X, Shen L, Hua T, Liu ZJ. Structural and Functional Insights into Cannabinoid Receptors. Trends in Pharmacological Sciences. PMID 32739033 DOI: 10.1016/j.tips.2020.06.010   
2020 Crevet L, Vanacker JM. Regulation of the expression of the estrogen related receptors (ERRs). Cellular and Molecular Life Sciences : Cmls. PMID 32448995 DOI: 10.1007/s00018-020-03549-0   
2020 Chen H, Fang QQ, Wang B. The age of paraffin block influences biomarker levels in archival breast cancer samples. Oncology Letters. 20: 525-532. PMID 32565978 DOI: 10.3892/ol.2020.11586   
2020 Dellal H, Boulahtouf A, Alaterre E, Cuenant A, Grimaldi M, Bourguet W, Gongora C, Balaguer P, Pourquier P. High Content Screening Using New U2OS Reporter Cell Models Identifies Harmol Hydrochloride as a Selective and Competitive Antagonist of the Androgen Receptor. Cells. 9. PMID 32560058 DOI: 10.3390/cells9061469   
2020 Burada AP, Vinnakota R, Kumar J. The Architecture of GluD2 Ionotropic Delta Glutamate Receptor Elucidated by cryo-EM. Journal of Structural Biology. 107546. PMID 32512155 DOI: 10.1016/j.jsb.2020.107546   
2020 Wang T, Cao Z, Shen Z, Yang J, Chen X, Yang Z, Xu K, Xiang X, Yu Q, Song Y, Wang W, Tian Y, Sun L, Zhang L, Guo S, et al. Existence and functions of a kisspeptin neuropeptide signaling system in a non-chordate deuterostome species. Elife. 9. PMID 32513385 DOI: 10.7554/eLife.53370   
2020 Abreu N, Levitz J. Optogenetic Techniques for Manipulating and Sensing G Protein-Coupled Receptor Signaling. Methods in Molecular Biology (Clifton, N.J.). 2173: 21-51. PMID 32651908 DOI: 10.1007/978-1-0716-0755-8_2   
2020 Zhang X, Meng R, Wang H, Xing J. Differential Effects of Components in Artemisia annua Extract on the Induction of Drug-Metabolizing Enzyme Expression Mediated by Nuclear Receptors. Planta Medica. PMID 32557519 DOI: 10.1055/a-1178-0852   
2020 Salazar H, Mischke S, Plested AJR. Measurements of the Timescale and Conformational Space of AMPA Receptor Desensitization. Biophysical Journal. PMID 32559412 DOI: 10.1016/j.bpj.2020.05.029   
2020 Jia J, Yue X, Zhu L, Jing S, Wang Y, Gim B, Qian Y, Lee I. KDEL receptor is a cell surface receptor that cycles between the plasma membrane and the Golgi via clathrin-mediated transport carriers. Cellular and Molecular Life Sciences : Cmls. PMID 32562023 DOI: 10.1007/s00018-020-03570-3   
2020 Mattedi G, Acosta-Gutiérrez S, Clark T, Gervasio FL. A combined activation mechanism for the glucagon receptor. Proceedings of the National Academy of Sciences of the United States of America. PMID 32571939 DOI: 10.1073/pnas.1921851117   
2020 Zhang W, Liu QY, Haqqani AS, Leclerc S, Liu Z, Fauteux F, Baumann E, Delaney CE, Ly D, Star AT, Brunette E, Sodja C, Hewitt M, Sandhu JK, Stanimirovic DB. Differential expression of receptors mediating receptor-mediated transcytosis (RMT) in brain microvessels, brain parenchyma and peripheral tissues of the mouse and the human. Fluids and Barriers of the Cns. 17: 47. PMID 32698806 DOI: 10.1186/s12987-020-00209-0   
2020 Friedman S, Tauber M, Ben-Chaim Y. Sodium ions allosterically modulate the M2 muscarinic receptor. Scientific Reports. 10: 11177. PMID 32636499 DOI: 10.1038/s41598-020-68133-9   
2020 Ojeda N, Salazar C, Cárdenas C, Marshall S. Expression of DC-SIGN-Like C-Type Lectin Receptors in Salmo salar. Developmental and Comparative Immunology. 103806. PMID 32739503 DOI: 10.1016/j.dci.2020.103806   
2020 Bekker R, Fjellaksel R, Hjornevik T, Nuruddin S, Rafique W, Hansen J, Sundset R, Haraldsen I, Riß PJ. Discovery of a lead brain-penetrating gonadotropin releasing hormone receptor antagonist with saturable binding in brain. Chemmedchem. PMID 32677155 DOI: 10.1002/cmdc.202000256   
2020 Thomas P, Pang Y. Anti-apoptotic Actions of Allopregnanolone and Ganaxolone Mediated Through Membrane Progesterone Receptors (PAQRs) in Neuronal Cells. Frontiers in Endocrinology. 11: 417. PMID 32670200 DOI: 10.3389/fendo.2020.00417   
2020 Warfvinge K, Krause DN, Maddahi A, Grell AS, Edvinsson JC, Haanes KA, Edvinsson L. Oxytocin as a regulatory neuropeptide in the trigeminovascular system: Localization, expression and function of oxytocin and oxytocin receptors. Cephalalgia : An International Journal of Headache. 333102420929027. PMID 32486908 DOI: 10.1177/0333102420929027   
2020 Liu K, Wu L, Yuan S, Wu M, Xu Y, Sun Q, Li S, Zhao S, Hua T, Liu ZJ. Structural basis of CXC chemokine receptor 2 activation and signalling. Nature. PMID 32610344 DOI: 10.1038/s41586-020-2492-5   
2020 Hazano K, Haneda S, Kayano M, Matsui M. Local sex steroid hormone milieu in the bovine oviduct ipsilateral and contralateral to preovulatory follicle or corpus luteum during the periovulatory phase. Domestic Animal Endocrinology. 74: 106515. PMID 32711284 DOI: 10.1016/j.domaniend.2020.106515   
2020 Xie Y, Xie W. . Drug Metabolism and Disposition: the Biological Fate of Chemicals. PMID 32587100 DOI: 10.1124/dmd.120.000074   
2020 Stephens BS, Ngo T, Kufareva I, Handel TM. Functional anatomy of the full-length CXCR4-CXCL12 complex systematically dissected by quantitative model-guided mutagenesis. Science Signaling. 13. PMID 32665413 DOI: 10.1126/scisignal.aay5024   
2020 Al Noman MA, Kyzer J, Chung SSW, Wolgemuth DJ, Georg GI. Retinoic acid receptor antagonists for male contraception: Current status. Biology of Reproduction. PMID 32671394 DOI: 10.1093/biolre/ioaa122   
2020 Hasegawa K, Maedomari R, Sato Y, Gotoh K, Kudoh S, Kojima A, Okada S, Ito T. Kiss1R identification and biodistribution analysis employing a western ligand blot and ligand-derivative stain with a FITC-kisspeptin derivative. Chemmedchem. PMID 32706162 DOI: 10.1002/cmdc.202000356   
2020 Greenhalgh JC, Chandran A, Harper MT, Ladds G, Rahman T. Proposed model of the Dictyostelium cAMP receptors bound to cAMP. Journal of Molecular Graphics & Modelling. 100: 107662. PMID 32659633 DOI: 10.1016/j.jmgm.2020.107662   
2020 Clark LJ, Krieger J, White AD, Bondarenko V, Lei S, Fang F, Lee JY, Doruker P, Böttke T, Jean-Alphonse F, Tang P, Gardella TJ, Xiao K, Sutkeviciute I, Coin I, et al. Allosteric interactions in the parathyroid hormone GPCR-arrestin complex formation. Nature Chemical Biology. PMID 32632293 DOI: 10.1038/s41589-020-0567-0   
2020 Toms D, Al-Ani A, Sunba S, Tong QYV, Workentine M, Ungrin M. Automated Hypothesis Generation to Identify Signals Relevant in the Development of Mammalian Cell and Tissue Bioprocesses, With Validation in a Retinal Culture System. Frontiers in Bioengineering and Biotechnology. 8: 534. PMID 32582664 DOI: 10.3389/fbioe.2020.00534   
2020 Möller J, Isbilir A, Sungkaworn T, Osberg B, Karathanasis C, Sunkara V, Grushevskyi EO, Bock A, Annibale P, Heilemann M, Schütte C, Lohse MJ. Single-molecule analysis reveals agonist-specific dimer formation of µ-opioid receptors. Nature Chemical Biology. PMID 32541966 DOI: 10.1038/s41589-020-0566-1   
2020 Richendrfer HA, Levy MM, Elsaid KA, Schmidt TA, Zhang L, Cabezas R, Jay GD. Recombinant Human Proteoglycan-4 Mediates Interleukin-6 Response in Both Human and Mouse Endothelial Cells Induced Into a Sepsis Phenotype. Critical Care Explorations. 2: e0126. PMID 32695993 DOI: 10.1097/CCE.0000000000000126   
2020 McMahon C, Staus DP, Wingler LM, Wang J, Skiba MA, Elgeti M, Hubbell WL, Rockman HA, Kruse AC, Lefkowitz RJ. Synthetic nanobodies as angiotensin receptor blockers. Proceedings of the National Academy of Sciences of the United States of America. PMID 32753386 DOI: 10.1073/pnas.2009029117   
2020 Nasrollahi-Shirazi S, Szöllösi D, Yang Q, Muratspahic E, El-Kasaby A, Sucic S, Stockner T, Nanoff C, Freissmuth M. Functional impact of the G279S substitution in the adenosine A1-receptor (A1R-G279S), a mutation associated with Parkinson's disease. Molecular Pharmacology. PMID 32641371 DOI: 10.1124/molpharm.120.000003   
2020 Cao C, Gilbert ER, Cline MA. The anorexigenic effect of beta-melanocyte-stimulating hormone involves corticotrophin-releasing factor and mesotocin in birds. Neuroscience Letters. 135282. PMID 32738351 DOI: 10.1016/j.neulet.2020.135282