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Nick Levinson, Ph.D. - Publications

Affiliations: 
University of Minnesota, Twin Cities, Minneapolis, MN 
Area:
Structural Biology of Cellular Signal Transduction and DNA Replication
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21 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Faber EB, Tian D, Burban D, Levinson NM, Hawkinson JE, Georg GI. Cooperativity Between Orthosteric Inhibitors and Allosteric Inhibitor 8-Anilino-1-Naphthalene Sulfonic Acid (ANS) in Cyclin-Dependent Kinase 2. Acs Chemical Biology. PMID 32433863 DOI: 10.1021/Acschembio.0C00169  0.551
2019 Edmund AB, Walseth TF, Levinson NM, Potter LR. The pseudokinase domains of guanylyl cyclase-A and -B allosterically increase the affinity of their catalytic domains for substrate. Science Signaling. 12. PMID 30696704 DOI: 10.1126/Scisignal.Aau5378  0.439
2018 Lake EW, Muretta JM, Thompson AR, Rasmussen DM, Majumdar A, Faber EB, Ruff EF, Thomas DD, Levinson NM. Quantitative conformational profiling of kinase inhibitors reveals origins of selectivity for Aurora kinase activation states. Proceedings of the National Academy of Sciences of the United States of America. PMID 30518564 DOI: 10.1073/Pnas.1811158115  0.695
2018 Albanese SK, Parton DL, Isik M, Rodríguez-Laureano L, Hanson SM, Behr JM, Gradia S, Jeans C, Levinson NM, Seeliger MA, Chodera JD. An open library of human kinase domain constructs for automated bacterial expression. Biochemistry. PMID 30004690 DOI: 10.1021/Acs.Biochem.7B01081  0.725
2018 Levinson NM. The multifaceted allosteric regulation of Aurora kinase A. The Biochemical Journal. 475: 2025-2042. PMID 29946042 DOI: 10.1042/BCJ20170771  0.515
2018 Ruff EF, Muretta JM, Thompson AR, Lake EW, Cyphers S, Albanese SK, Hanson SM, Behr JM, Thomas DD, Chodera JD, Levinson NM. A dynamic mechanism for allosteric activation of Aurora kinase A by activation loop phosphorylation. Elife. 7. PMID 29465396 DOI: 10.7554/Elife.32766  0.809
2017 Cyphers S, Ruff EF, Behr JM, Chodera JD, Levinson NM. A water-mediated allosteric network governs activation of Aurora kinase A. Nature Chemical Biology. PMID 28166210 DOI: 10.1038/Nchembio.2296  0.446
2016 Hanson SM, Rodriguez L, Behr JM, Rizzi A, Parton DL, Beauchamp KA, Fass JH, Prinz J, Boyce SE, Seeliger MA, Levinson NM, Chodera JD. Dissecting the Contribution of Kinase Conformational Reorganization Energies to Inhibitor Selectivity Biophysical Journal. 110: 545a. DOI: 10.1016/J.Bpj.2015.11.2918  0.74
2014 Levinson NM, Boxer SG. A conserved water-mediated hydrogen bond network defines bosutinib's kinase selectivity. Nature Chemical Biology. 10: 127-32. PMID 24292070 DOI: 10.1038/Nchembio.1404  0.645
2014 Levinson NM, Boxer SG. A Conserved Water-Mediated Hydrogen Bond Network Underlies Selectivity of the Kinase Inhibitor Bosutinib Biophysical Journal. 106: 647a. DOI: 10.1016/J.Bpj.2013.11.3579  0.619
2013 Boxer S, Bagchi S, Fried SD, Levinson N, Saggu M, Xu L. Vibrational Stark Spectroscopy Directly Probes Electric Fields in Proteins Biophysical Journal. 104: 355a. DOI: 10.1016/J.Bpj.2012.11.1970  0.72
2012 Saggu M, Levinson NM, Boxer SG. Experimental quantification of electrostatics in X-H···π hydrogen bonds. Journal of the American Chemical Society. 134: 18986-97. PMID 23098379 DOI: 10.1021/Ja305575T  0.405
2012 Levinson NM, Boxer SG. Structural and spectroscopic analysis of the kinase inhibitor bosutinib and an isomer of bosutinib binding to the Abl tyrosine kinase domain. Plos One. 7: e29828. PMID 22493660 DOI: 10.1371/Journal.Pone.0029828  0.68
2012 Levinson NM, Fried SD, Boxer SG. Solvent-induced infrared frequency shifts in aromatic nitriles are quantitatively described by the vibrational Stark effect. The Journal of Physical Chemistry. B. 116: 10470-6. PMID 22448878 DOI: 10.1021/Jp301054E  0.662
2012 Levinson N, Boxer SG. Kinome-Wide Spectroscopic Study of Drug Binding Site Electrostatics Biophysical Journal. 102: 410a-411a. DOI: 10.1016/J.Bpj.2011.11.2244  0.685
2011 Saggu M, Levinson NM, Boxer SG. Direct measurements of electric fields in weak OH···π hydrogen bonds. Journal of the American Chemical Society. 133: 17414-9. PMID 21936553 DOI: 10.1021/Ja2069592  0.431
2011 Levinson NM, Bolte EE, Miller CS, Corcelli SA, Boxer SG. Phosphate vibrations probe local electric fields and hydration in biomolecules. Journal of the American Chemical Society. 133: 13236-9. PMID 21809829 DOI: 10.1021/Ja2042589  0.437
2010 Levinson N, Boxer S. The Phosphorus-Oxygen Bond As An Intrinsic Vibrational Probe of Electric Field in Biological Systems Biophysical Journal. 98: 45a. DOI: 10.1016/J.Bpj.2009.12.260  0.507
2009 Levinson NM, Visperas PR, Kuriyan J. The tyrosine kinase Csk dimerizes through its SH3 domain Plos One. 4. PMID 19888460 DOI: 10.1371/Journal.Pone.0007683  0.74
2008 Levinson NM, Seeliger MA, Cole PA, Kuriyan J. Structural Basis for the Recognition of c-Src by Its Inactivator Csk Cell. 134: 124-134. PMID 18614016 DOI: 10.1016/J.Cell.2008.05.051  0.788
2006 Levinson NM, Kuchment O, Shen K, Young MA, Koldobskiy M, Karplus M, Cole PA, Kuriyan J. A Src-like inactive conformation in the abl tyrosine kinase domain. Plos Biology. 4: e144. PMID 16640460 DOI: 10.1371/Journal.Pbio.0040144  0.748
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