| Year |
Citation |
Score |
| 2023 |
Woerz F, Hoffmann F, Antony S, Bolz S, Jarboui MA, Junger K, Klose F, Stehle IF, Boldt K, Ueffing M, Beyer T. Interactome analysis reveals a link of the novel ALMS1-CEP70 complex to centrosomal clusters. Molecular & Cellular Proteomics : McP. 100701. PMID 38122899 DOI: 10.1016/j.mcpro.2023.100701 |
0.316 |
|
| 2023 |
Hoffmann F, Bolz S, Junger K, Klose F, Stehle IF, Ueffing M, Boldt K, Beyer T. Paralog-specific TTC30 regulation of Sonic hedgehog signaling. Frontiers in Molecular Biosciences. 10: 1268722. PMID 38074101 DOI: 10.3389/fmolb.2023.1268722 |
0.325 |
|
| 2013 |
Goodman CA, McNally RM, Hoffmann FM, Hornberger TA. Smad3 induces atrogin-1, inhibits mTOR and protein synthesis, and promotes muscle atrophy in vivo. Molecular Endocrinology (Baltimore, Md.). 27: 1946-57. PMID 24002653 DOI: 10.1210/Me.2013-1194 |
0.349 |
|
| 2013 |
Zeng H, Wu J, Bedford MT, Sbardella G, Hoffmann FM, Bi K, Xu W. A TR-FRET-based functional assay for screening activators of CARM1. Chembiochem : a European Journal of Chemical Biology. 14: 827-35. PMID 23585185 DOI: 10.1002/Cbic.201300029 |
0.333 |
|
| 2012 |
Das S, Becker BN, Hoffmann FM, Mertz JE. Reversal of transforming growth factor-β induced epithelial-to-mesenchymal transition and the ZEB proteins. Fibrogenesis & Tissue Repair. 5: S28. PMID 23259633 DOI: 10.1186/1755-1536-5-S1-S28 |
0.336 |
|
| 2011 |
Schiro MM, Stauber SE, Peterson TL, Krueger C, Darnell SJ, Satyshur KA, Drinkwater NR, Newton MA, Hoffmann FM. Mutations in protein-binding hot-spots on the hub protein Smad3 differentially affect its protein interactions and Smad3-regulated gene expression. Plos One. 6: e25021. PMID 21949838 DOI: 10.1371/Journal.Pone.0025021 |
0.692 |
|
| 2010 |
Krueger C, Hoffmann FM. Identification of retinoic acid in a high content screen for agents that overcome the anti-myogenic effect of TGF-beta-1. Plos One. 5: e15511. PMID 21152098 DOI: 10.1371/journal.pone.0015511 |
0.379 |
|
| 2010 |
Powell E, Huang SX, Xu Y, Rajski SR, Wang Y, Peters N, Guo S, Xu HE, Hoffmann FM, Shen B, Xu W. Identification and characterization of a novel estrogenic ligand actinopolymorphol A. Biochemical Pharmacology. 80: 1221-9. PMID 20599778 DOI: 10.1016/J.Bcp.2010.06.030 |
0.364 |
|
| 2010 |
Luo Y, Li W, Ju J, Yuan Q, Peters NR, Hoffmann FM, Huang SX, Bugni TS, Rajski S, Osada H, Shen B. Functional characterization of TtnD and TtnF, unveiling new insights into tautomycetin biosynthesis. Journal of the American Chemical Society. 132: 6663-71. PMID 20426415 DOI: 10.1021/Ja9082446 |
0.338 |
|
| 2009 |
Das S, Becker BN, Hoffmann FM, Mertz JE. Complete reversal of epithelial to mesenchymal transition requires inhibition of both ZEB expression and the Rho pathway. Bmc Cell Biology. 10: 94. PMID 20025777 DOI: 10.1186/1471-2121-10-94 |
0.396 |
|
| 2009 |
Ju J, Li W, Yuan Q, Peters NR, Hoffmann FM, Rajski SR, Osada H, Shen B. Functional characterization of ttmM unveils new tautomycin analogs and insight into tautomycin biosynthesis and activity. Organic Letters. 11: 1639-42. PMID 19281218 DOI: 10.1021/Ol900293J |
0.366 |
|
| 2009 |
Ju J, Rajski SR, Lim SK, Seo JW, Peters NR, Hoffmann FM, Shen B. Lactimidomycin, iso-migrastatin and related glutarimide-containing 12-membered macrolides are extremely potent inhibitors of cell migration. Journal of the American Chemical Society. 131: 1370-1. PMID 19132897 DOI: 10.1021/Ja808462P |
0.537 |
|
| 2008 |
Ju J, Rajski SR, Lim SK, Seo JW, Peters NR, Hoffmann FM, Shen B. Evaluation of new migrastatin and dorrigocin congeners unveils cell migration inhibitors with dramatically improved potency. Bioorganic & Medicinal Chemistry Letters. 18: 5951-4. PMID 18684620 DOI: 10.1016/J.Bmcl.2008.07.072 |
0.521 |
|
| 2007 |
Yang B, O'Herrin SM, Wu J, Reagan-Shaw S, Ma Y, Bhat KM, Gravekamp C, Setaluri V, Peters N, Hoffmann FM, Peng H, Ivanov AV, Simpson AJ, Longley BJ. MAGE-A, mMage-b, and MAGE-C proteins form complexes with KAP1 and suppress p53-dependent apoptosis in MAGE-positive cell lines. Cancer Research. 67: 9954-62. PMID 17942928 DOI: 10.1158/0008-5472.CAN-07-1478 |
0.358 |
|
| 2006 |
Lim SK, Hoffmann FM. Smad4 cooperates with lymphoid enhancer-binding factor 1/T cell-specific factor to increase c-myc expression in the absence of TGF-beta signaling. Proceedings of the National Academy of Sciences of the United States of America. 103: 18580-5. PMID 17132729 DOI: 10.1073/pnas.0604773103 |
0.626 |
|
| 2006 |
Zhao BM, Hoffmann FM. Inhibition of transforming growth factor-beta1-induced signaling and epithelial-to-mesenchymal transition by the Smad-binding peptide aptamer Trx-SARA. Molecular Biology of the Cell. 17: 3819-31. PMID 16775010 DOI: 10.1091/Mbc.E05-10-0990 |
0.778 |
|
| 2005 |
Martin M, Ahern-Djamali SM, Hoffmann FM, Saxton WM. Abl tyrosine kinase and its substrate Ena/VASP have functional interactions with kinesin-1. Molecular Biology of the Cell. 16: 4225-30. PMID 15975902 DOI: 10.1091/Mbc.E05-02-0116 |
0.368 |
|
| 2005 |
Cui Q, Lim SK, Zhao B, Hoffmann FM. Selective inhibition of TGF-beta responsive genes by Smad-interacting peptide aptamers from FoxH1, Lef1 and CBP. Oncogene. 24: 3864-74. PMID 15750622 DOI: 10.1038/Sj.Onc.1208556 |
0.787 |
|
| 1998 |
Ahern-Djamali SM, Comer AR, Bachmann C, Kastenmeier AS, Reddy SK, Beckerle MC, Walter U, Hoffmann FM. Mutations in Drosophila enabled and rescue by human vasodilator-stimulated phosphoprotein (VASP) indicate important functional roles for Ena/VASP homology domain 1 (EVH1) and EVH2 domains. Molecular Biology of the Cell. 9: 2157-71. PMID 9693373 DOI: 10.1091/Mbc.9.8.2157 |
0.383 |
|
| 1997 |
Singer MA, Penton A, Twombly V, Hoffmann FM, Gelbart WM. Signaling through both type I DPP receptors is required for anterior-posterior patterning of the entire Drosophila wing. Development (Cambridge, England). 124: 79-89. PMID 9006069 |
0.754 |
|
| 1996 |
Morimura S, Maves L, Chen Y, Hoffmann FM. decapentaplegic overexpression affects Drosophila wing and leg imaginal disc development and wingless expression. Developmental Biology. 177: 136-51. PMID 8660883 DOI: 10.1006/dbio.1996.0151 |
0.349 |
|
| 1995 |
Hill KK, Bedian V, Juang JL, Hoffmann FM. Genetic interactions between the Drosophila Abelson (Abl) tyrosine kinase and failed axon connections (fax), a novel protein in axon bundles. Genetics. 141: 595-606. PMID 8647396 |
0.338 |
|
| 1995 |
Letsou A, Arora K, Wrana JL, Simin K, Twombly V, Jamal J, Staehling-Hampton K, Hoffmann FM, Gelbart WM, Massagué J. Drosophila Dpp signaling is mediated by the punt gene product: a dual ligand-binding type II receptor of the TGF beta receptor family. Cell. 80: 899-908. PMID 7697720 DOI: 10.1016/0092-8674(95)90293-7 |
0.775 |
|
| 1995 |
Holley SA, Jackson PD, Sasai Y, Lu B, De Robertis EM, Hoffmann FM, Ferguson EL. A conserved system for dorsal-ventral patterning in insects and vertebrates involving sog and chordin. Nature. 376: 249-53. PMID 7617035 DOI: 10.1038/376249a0 |
0.399 |
|
| 1995 |
Staehling-Hampton K, Laughon AS, Hoffmann FM. A Drosophila protein related to the human zinc finger transcription factor PRDII/MBPI/HIV-EP1 is required for dpp signaling. Development (Cambridge, England). 121: 3393-403. PMID 7588072 |
0.342 |
|
| 1995 |
Gertler FB, Comer AR, Juang JL, Ahern SM, Clark MJ, Liebl EC, Hoffmann FM. enabled, a dosage-sensitive suppressor of mutations in the Drosophila Abl tyrosine kinase, encodes an Abl substrate with SH3 domain-binding properties. Genes & Development. 9: 521-33. PMID 7535279 DOI: 10.1101/Gad.9.5.521 |
0.587 |
|
| 1994 |
Jackson PD, Hoffmann FM. Embryonic expression patterns of the Drosophila decapentaplegic gene: separate regulatory elements control blastoderm expression and lateral ectodermal expression. Developmental Dynamics : An Official Publication of the American Association of Anatomists. 199: 28-44. PMID 8167377 DOI: 10.1002/aja.1001990104 |
0.377 |
|
| 1994 |
Penton A, Chen Y, Staehling-Hampton K, Wrana JL, Attisano L, Szidonya J, Cassill JA, Massagué J, Hoffmann FM. Identification of two bone morphogenetic protein type I receptors in Drosophila and evidence that Brk25D is a decapentaplegic receptor. Cell. 78: 239-50. PMID 8044838 DOI: 10.1016/0092-8674(94)90294-1 |
0.498 |
|
| 1994 |
Staehling-Hampton K, Hoffmann FM, Baylies MK, Rushton E, Bate M. dpp induces mesodermal gene expression in Drosophila. Nature. 372: 783-6. PMID 7997266 DOI: 10.1038/372783A0 |
0.481 |
|
| 1994 |
Staehling-Hampton K, Hoffmann FM. Ectopic decapentaplegic in the Drosophila midgut alters the expression of five homeotic genes, dpp, and wingless, causing specific morphological defects. Developmental Biology. 164: 502-12. PMID 7913899 DOI: 10.1006/dbio.1994.1219 |
0.343 |
|
| 1993 |
Masucci JD, Hoffmann FM. Identification of two regions from the Drosophila decapentaplegic gene required for embryonic midgut development and larval viability. Developmental Biology. 159: 276-87. PMID 8365566 DOI: 10.1006/dbio.1993.1240 |
0.386 |
|
| 1993 |
Gertler FB, Hill KK, Clark MJ, Hoffmann FM. Dosage-sensitive modifiers of Drosophila abl tyrosine kinase function: prospero, a regulator of axonal outgrowth, and disabled, a novel tyrosine kinase substrate. Genes & Development. 7: 441-53. PMID 7680635 DOI: 10.1101/Gad.7.3.441 |
0.57 |
|
| 1992 |
Hoffmann FM, Sternberg PW, Herskowitz I. Learning about cancer genes through invertebrate genetics. Current Opinion in Genetics & Development. 2: 45-52. PMID 1633426 DOI: 10.1016/S0959-437X(05)80320-X |
0.39 |
|
| 1992 |
Doctor JS, Jackson PD, Rashka KE, Visalli M, Hoffmann FM. Sequence, biochemical characterization, and developmental expression of a new member of the TGF-beta superfamily in Drosophila melanogaster. Developmental Biology. 151: 491-505. PMID 1601181 |
0.37 |
|
| 1992 |
Hoffmann FM. TGF-beta family factors in Drosophila morphogenesis. Molecular Reproduction and Development. 32: 173-8. PMID 1353353 DOI: 10.1002/mrd.1080320214 |
0.5 |
|
| 1992 |
Bennett RL, Hoffmann FM. Increased levels of the Drosophila Abelson tyrosine kinase in nerves and muscles: subcellular localization and mutant phenotypes imply a role in cell-cell interactions. Development (Cambridge, England). 116: 953-66. PMID 1295746 |
0.572 |
|
| 1991 |
Hoffmann FM. Transforming growth factor-beta-related genes in Drosophila and vertebrate development. Current Opinion in Cell Biology. 3: 947-52. PMID 1687650 DOI: 10.1016/0955-0674(91)90112-C |
0.515 |
|
| 1990 |
Elkins T, Zinn K, McAllister L, Hoffmann FM, Goodman CS. Genetic analysis of a Drosophila neural cell adhesion molecule: interaction of fasciclin I and Abelson tyrosine kinase mutations. Cell. 60: 565-75. PMID 2406026 DOI: 10.1016/0092-8674(90)90660-7 |
0.394 |
|
| 1990 |
Gertler FB, Doctor JS, Hoffmann FM. Genetic suppression of mutations in the Drosophila abl proto-oncogene homolog. Science (New York, N.Y.). 248: 857-60. PMID 2188361 DOI: 10.1126/Science.2188361 |
0.591 |
|
| 1990 |
Henkemeyer M, West SR, Gertler FB, Hoffmann FM. A novel tyrosine kinase-independent function of Drosophila abl correlates with proper subcellular localization. Cell. 63: 949-60. PMID 2175256 DOI: 10.1016/0092-8674(90)90498-4 |
0.601 |
|
| 1990 |
St Johnston RD, Hoffmann FM, Blackman RK, Segal D, Grimaila R, Padgett RW, Irick HA, Gelbart WM. Molecular organization of the decapentaplegic gene in Drosophila melanogaster. Genes & Development. 4: 1114-27. PMID 2120113 DOI: 10.1101/Gad.4.7.1114 |
0.788 |
|
| 1990 |
Muskavitch MA, Hoffmann FM. Homologs of vertebrate growth factors in Drosophila melanogaster and other invertebrates. Current Topics in Developmental Biology. 24: 289-328. PMID 2116263 |
0.338 |
|
| 1990 |
Panganiban GE, Reuter R, Scott MP, Hoffmann FM. A Drosophila growth factor homolog, decapentaplegic, regulates homeotic gene expression within and across germ layers during midgut morphogenesis. Development (Cambridge, England). 110: 1041-50. PMID 1983114 |
0.384 |
|
| 1990 |
Reuter R, Panganiban GE, Hoffmann FM, Scott MP. Homeotic genes regulate the spatial expression of putative growth factors in the visceral mesoderm of Drosophila embryos. Development (Cambridge, England). 110: 1031-40. PMID 1983113 |
0.391 |
|
| 1990 |
Panganiban GE, Rashka KE, Neitzel MD, Hoffmann FM. Biochemical characterization of the Drosophila dpp protein, a member of the transforming growth factor beta family of growth factors. Molecular and Cellular Biology. 10: 2669-77. PMID 1692958 |
0.351 |
|
| 1989 |
Hoffmann FM. Roles of Drosophila proto-oncogene and growth factor homologs during development of the fly. Current Topics in Microbiology and Immunology. 147: 1-29. PMID 2515942 DOI: 10.1007/978-3-642-74697-0_1 |
0.345 |
|
| 1989 |
Gertler FB, Bennett RL, Clark MJ, Hoffmann FM. Drosophila abl tyrosine kinase in embryonic CNS axons: a role in axonogenesis is revealed through dosage-sensitive interactions with disabled. Cell. 58: 103-13. PMID 2502313 DOI: 10.1016/0092-8674(89)90407-8 |
0.689 |
|
| 1988 |
Henkemeyer MJ, Bennett RL, Gertler FB, Hoffmann FM. DNA sequence, structure, and tyrosine kinase activity of the Drosophila melanogaster Abelson proto-oncogene homolog. Molecular and Cellular Biology. 8: 843-53. PMID 2832740 DOI: 10.1128/Mcb.8.2.843 |
0.706 |
|
| 1987 |
Henkemeyer MJ, Gertler FB, Goodman W, Hoffmann FM. The Drosophila Abelson proto-oncogene homolog: identification of mutant alleles that have pleiotropic effects late in development. Cell. 51: 821-8. PMID 3119227 DOI: 10.1016/0092-8674(87)90105-X |
0.618 |
|
| 1987 |
Hoffmann FM, Goodman W. Identification in transgenic animals of the Drosophila decapentaplegic sequences required for embryonic dorsal pattern formation. Genes & Development. 1: 615-25. PMID 2824286 |
0.375 |
|
| 1985 |
Gelbart WM, Irish VF, St Johnston RD, Hoffmann FM, Blackman RK, Segal D, Posakony LM, Grimaila R. The decapentaplegic gene complex in Drosophila melanogaster. Cold Spring Harbor Symposia On Quantitative Biology. 50: 119-25. PMID 3938359 DOI: 10.1101/Sqb.1985.050.01.017 |
0.657 |
|
| 1982 |
Spencer FA, Hoffmann FM, Gelbart WM. Decapentaplegic: a gene complex affecting morphogenesis in Drosophila melanogaster. Cell. 28: 451-61. PMID 6804094 DOI: 10.1016/0092-8674(82)90199-4 |
0.71 |
|
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