Timothy L. Foley, Ph.D. - Publications

Affiliations: 
2010 Chemistry University of California, San Diego, La Jolla, CA 
Area:
Natural product synthesis/biosynthesis, Biological chemistry and enzymology, Metabolic engineering

16 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2017 Butler CR, Beck EM, Harris AR, Huang Z, McAllister LA, Am Ende CW, Fennell KF, Foley TL, Fonseca KR, Hawrylik SJ, Johnson DS, Knafels JD, Mente S, Noell S, Pandit J, et al. Azetidine and Piperidine Carbamates as Efficient, Covalent Inhibitors of Monoacylglycerol Lipase. Journal of Medicinal Chemistry. PMID 29148769 DOI: 10.1021/Acs.Jmedchem.7B01531  0.302
2017 Gopalsamy A, Narayanan A, Liu S, Parikh MD, Kyne RE, Fadeyi OO, Tones MA, Cherry JJ, Nabhan JF, LaRosa G, Petersen DN, Menard CA, Foley TL, Noell S, Ren Y, et al. Design of Potent mRNA Decapping Scavenger Enzyme (DcpS) Inhibitors with Improved Physicochemical Properties to Investigate the Mechanism of Therapeutic Benefit in Spinal Muscular Atrophy (SMA). Journal of Medicinal Chemistry. PMID 28257199 DOI: 10.1021/Acs.Jmedchem.7B00124  0.324
2016 Foley TL, Dorjsuren D, Dexheimer TS, Burkart MD, Wight WC, Simeonov A. A Platform to Enable the Pharmacological Profiling of Small Molecules in Gel-Based Electrophoretic Mobility Shift Assays. Journal of Biomolecular Screening. PMID 27269812 DOI: 10.1177/1087057116652895  0.517
2014 Cavalier MC, Pierce AD, Wilder PT, Alasady MJ, Hartman KG, Neau DB, Foley TL, Jadhav A, Maloney DJ, Simeonov A, Toth EA, Weber DJ. Covalent small molecule inhibitors of Ca(2+)-bound S100B. Biochemistry. 53: 6628-40. PMID 25268459 DOI: 10.1021/Bi5005552  0.374
2014 Foley TL, Rai G, Yasgar A, Daniel T, Baker HL, Attene-Ramos M, Kosa NM, Leister W, Burkart MD, Jadhav A, Simeonov A, Maloney DJ. 4-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)-N-(4-methoxypyridin-2-yl)piperazine-1-carbothioamide (ML267), a potent inhibitor of bacterial phosphopantetheinyl transferase that attenuates secondary metabolism and thwarts bacterial growth. Journal of Medicinal Chemistry. 57: 1063-78. PMID 24450337 DOI: 10.1021/Jm401752P  0.655
2014 Kosa NM, Foley TL, Burkart MD. Fluorescent techniques for discovery and characterization of phosphopantetheinyl transferase inhibitors. The Journal of Antibiotics. 67: 113-20. PMID 24192555 DOI: 10.1038/Ja.2013.106  0.671
2010 Yu WL, Guizzunti G, Foley TL, Burkart MD, La Clair JJ. An optimized immunoaffinity fluorescent method for natural product target elucidation. Journal of Natural Products. 73: 1659-66. PMID 20836515 DOI: 10.1021/Np100371K  0.57
2010 Foley TL, Yasgar A, Garcia CJ, Jadhav A, Simeonov A, Burkart MD. Preparation of FRET reporters to support chemical probe development. Organic & Biomolecular Chemistry. 8: 4601-6. PMID 20725690 DOI: 10.1039/C0Ob00322K  0.525
2010 Yasgar A, Foley TL, Jadhav A, Inglese J, Burkart MD, Simeonov A. A strategy to discover inhibitors of Bacillus subtilis surfactin-type phosphopantetheinyl transferase. Molecular Biosystems. 6: 365-75. PMID 20094656 DOI: 10.1039/B913291K  0.649
2009 Foley TL, Young BS, Burkart MD. Phosphopantetheinyl transferase inhibition and secondary metabolism. The Febs Journal. 276: 7134-45. PMID 19895578 DOI: 10.1111/J.1742-4658.2009.07425.X  0.613
2009 Lear MJ, Simon O, Foley TL, Burkart MD, Baiga TJ, Noel JP, DiPasquale AG, Rheingold AL, La Clair JJ. Laetirobin from the parasitic growth of Laetiporus sulphureus on Robinia pseudoacacia. Journal of Natural Products. 72: 1980-7. PMID 19842686 DOI: 10.1021/Np9002838  0.479
2009 Meier JL, Niessen S, Hoover HS, Foley TL, Cravatt BF, Burkart MD. An orthogonal active site identification system (OASIS) for proteomic profiling of natural product biosynthesis. Acs Chemical Biology. 4: 948-57. PMID 19785476 DOI: 10.1021/Cb9002128  0.682
2009 Foley TL, Burkart MD. A homogeneous resonance energy transfer assay for phosphopantetheinyl transferase. Analytical Biochemistry. 394: 39-47. PMID 19573516 DOI: 10.1016/J.Ab.2009.06.037  0.602
2008 Meier JL, Barrows-Yano T, Foley TL, Wike CL, Burkart MD. The unusual macrocycle forming thioesterase of mycolactone. Molecular Biosystems. 4: 663-71. PMID 18493665 DOI: 10.1039/B801397G  0.67
2007 Foley TL, Burkart MD. Site-specific protein modification: advances and applications. Current Opinion in Chemical Biology. 11: 12-9. PMID 17189712 DOI: 10.1016/J.Cbpa.2006.11.036  0.534
2004 La Clair JJ, Foley TL, Schegg TR, Regan CM, Burkart MD. Manipulation of carrier proteins in antibiotic biosynthesis. Chemistry & Biology. 11: 195-201. PMID 15123281 DOI: 10.1016/J.Chembiol.2004.02.010  0.612
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