Iswar Hariharan - Publications

Affiliations: 
Molecular and Cell Biology University of California, Berkeley, Berkeley, CA, United States 
Area:
Mechanisms of control of growth and cell proliferation, Regulation of regenerative growth.

55 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Spitzer DC, Sun WY, Rodríguez-Vargas A, Hariharan IK. The cell adhesion molecule Echinoid promotes tissue survival and separately restricts tissue overgrowth in imaginal discs. Biorxiv : the Preprint Server For Biology. PMID 37577631 DOI: 10.1101/2023.08.04.552072  0.464
2023 Friesen S, Hariharan IK. Coordinated growth of linked epithelia is mediated by the Hippo pathway. Biorxiv : the Preprint Server For Biology. PMID 36993542 DOI: 10.1101/2023.02.26.530099  0.312
2022 Worley MI, Everetts NJ, Yasutomi R, Chang RJ, Saretha S, Yosef N, Hariharan IK. Ets21C sustains a pro-regenerative transcriptional program in blastema cells of Drosophila imaginal discs. Current Biology : Cb. PMID 35820420 DOI: 10.1016/j.cub.2022.06.040  0.355
2021 Everetts NJ, Worley MI, Yasutomi R, Yosef N, Hariharan IK. Single-cell transcriptomics of the wing disc reveals instructive epithelium-to-myoblast interactions. Elife. 10. PMID 33749594 DOI: 10.7554/eLife.61276  0.322
2020 Bairzin JCD, Emmons-Bell M, Hariharan IK. The Hippo pathway coactivator Yorkie can reprogram cell fates and create compartment-boundary-like interactions at clone margins. Science Advances. 6. PMID 33298454 DOI: 10.1126/sciadv.abe8159  0.341
2018 Setiawan L, Pan X, Woods AL, O'Connor MB, Hariharan IK. The BMP2/4 ortholog Dpp can function as an inter-organ signal that regulates developmental timing. Life Science Alliance. 1: e201800216. PMID 30515478 DOI: 10.26508/lsa.201800216  0.319
2018 Worley MI, Alexander LA, Hariharan IK. CtBP impedes JNK- and Upd/STAT-driven cell fate misspecifications in regenerating Drosophila imaginal discs. Elife. 7. PMID 29372681 DOI: 10.7554/eLife.30391  0.443
2016 Bosch JA, Sumabat TM, Hariharan IK. Persistence of RNAi-Mediated Knockdown in Drosophila Complicates Mosaic Analysis yet Enables Highly Sensitive Lineage Tracing. Genetics. PMID 26984059 DOI: 10.1534/genetics.116.187062  0.31
2015 Hariharan IK. Organ Size Control: Lessons from Drosophila. Developmental Cell. 34: 255-65. PMID 26267393 DOI: 10.1016/j.devcel.2015.07.012  0.339
2015 Bosch JA, Tran NH, Hariharan IK. CoinFLP: a system for efficient mosaic screening and for visualizing clonal boundaries in Drosophila. Development (Cambridge, England). 142: 597-606. PMID 25605786 DOI: 10.1242/dev.114603  0.316
2014 Bosch JA, Sumabat TM, Hafezi Y, Pellock BJ, Gandhi KD, Hariharan IK. The Drosophila F-box protein Fbxl7 binds to the protocadherin fat and regulates Dachs localization and Hippo signaling. Elife. 3: e03383. PMID 25107277 DOI: 10.7554/Elife.03383  0.727
2013 Worley MI, Setiawan L, Hariharan IK. TIE-DYE: a combinatorial marking system to visualize and genetically manipulate clones during development in Drosophila melanogaster. Development (Cambridge, England). 140: 3275-84. PMID 23785055 DOI: 10.1242/dev.096057  0.363
2013 Kanda H, Nguyen A, Chen L, Okano H, Hariharan IK. The Drosophila ortholog of MLL3 and MLL4, trithorax related, functions as a negative regulator of tissue growth. Molecular and Cellular Biology. 33: 1702-10. PMID 23459941 DOI: 10.1128/Mcb.01585-12  0.668
2012 Worley MI, Setiawan L, Hariharan IK. Regeneration and transdetermination in Drosophila imaginal discs. Annual Review of Genetics. 46: 289-310. PMID 22934642 DOI: 10.1146/annurev-genet-110711-155637  0.305
2012 Harvey KF, Hariharan IK. The hippo pathway. Cold Spring Harbor Perspectives in Biology. 4: a011288. PMID 22745287 DOI: 10.1101/cshperspect.a011288  0.5
2012 Hafezi Y, Bosch JA, Hariharan IK. Differences in levels of the transmembrane protein Crumbs can influence cell survival at clonal boundaries. Developmental Biology. 368: 358-69. PMID 22683826 DOI: 10.1016/J.Ydbio.2012.06.001  0.81
2011 Gerhold AR, Richter DJ, Yu AS, Hariharan IK. Identification and characterization of genes required for compensatory growth in Drosophila. Genetics. 189: 1309-26. PMID 21926302 DOI: 10.1534/Genetics.111.132993  0.398
2010 Reis T, Van Gilst MR, Hariharan IK. A buoyancy-based screen of Drosophila larvae for fat-storage mutants reveals a role for Sir2 in coupling fat storage to nutrient availability. Plos Genetics. 6: e1001206. PMID 21085633 DOI: 10.1371/journal.pgen.1001206  0.616
2010 Siegrist SE, Haque NS, Chen CH, Hay BA, Hariharan IK. Inactivation of both Foxo and reaper promotes long-term adult neurogenesis in Drosophila. Current Biology : Cb. 20: 643-8. PMID 20346676 DOI: 10.1016/J.Cub.2010.01.060  0.542
2010 Herz HM, Madden LD, Chen Z, Bolduc C, Buff E, Gupta R, Davuluri R, Shilatifard A, Hariharan IK, Bergmann A. The H3K27me3 demethylase dUTX is a suppressor of Notch- and Rb-dependent tumors in Drosophila. Molecular and Cellular Biology. 30: 2485-97. PMID 20212086 DOI: 10.1128/Mcb.01633-09  0.797
2010 Halme A, Cheng M, Hariharan IK. Retinoids regulate a developmental checkpoint for tissue regeneration in Drosophila. Current Biology : Cb. 20: 458-63. PMID 20189388 DOI: 10.1016/j.cub.2010.01.038  0.775
2009 Smith-Bolton RK, Worley MI, Kanda H, Hariharan IK. Regenerative growth in Drosophila imaginal discs is regulated by Wingless and Myc. Developmental Cell. 16: 797-809. PMID 19531351 DOI: 10.1016/J.Devcel.2009.04.015  0.789
2008 Harvey KF, Mattila J, Sofer A, Bennett FC, Ramsey MR, Ellisen LW, Puig O, Hariharan IK. FOXO-regulated transcription restricts overgrowth of Tsc mutant organs. The Journal of Cell Biology. 180: 691-6. PMID 18299344 DOI: 10.1083/jcb.200710100  0.642
2007 Pfleger CM, Harvey KF, Yan H, Hariharan IK. Mutation of the gene encoding the ubiquitin activating enzyme ubal causes tissue overgrowth in Drosophila. Fly. 1: 95-105. PMID 18820468 DOI: 10.4161/Fly.4285  0.801
2007 Tseng AS, Tapon N, Kanda H, Cigizoglu S, Edelmann L, Pellock B, White K, Hariharan IK. Capicua regulates cell proliferation downstream of the receptor tyrosine kinase/ras signaling pathway. Current Biology : Cb. 17: 728-33. PMID 17398096 DOI: 10.1016/J.Cub.2007.03.023  0.793
2007 Pellock BJ, Buff E, White K, Hariharan IK. The Drosophila tumor suppressors Expanded and Merlin differentially regulate cell cycle exit, apoptosis, and Wingless signaling. Developmental Biology. 304: 102-15. PMID 17258190 DOI: 10.1016/J.Ydbio.2006.12.021  0.795
2006 Hariharan IK. Growth regulation: a beginning for the hippo pathway. Current Biology : Cb. 16: R1037-9. PMID 17174912 DOI: 10.1016/j.cub.2006.11.012  0.348
2006 Walker JA, Tchoudakova AV, McKenney PT, Brill S, Wu D, Cowley GS, Hariharan IK, Bernards A. Reduced growth of Drosophila neurofibromatosis 1 mutants reflects a non-cell-autonomous requirement for GTPase-Activating Protein activity in larval neurons. Genes & Development. 20: 3311-23. PMID 17114577 DOI: 10.1101/Gad.1466806  0.33
2006 Hariharan IK, Bilder D. Regulation of imaginal disc growth by tumor-suppressor genes in Drosophila. Annual Review of Genetics. 40: 335-61. PMID 16872256 DOI: 10.1146/annurev.genet.39.073003.100738  0.4
2006 Mills K, Daish T, Harvey KF, Pfleger CM, Hariharan IK, Kumar S. The Drosophila melanogaster Apaf-1 homologue ARK is required for most, but not all, programmed cell death. The Journal of Cell Biology. 172: 809-15. PMID 16533943 DOI: 10.1083/jcb.200512126  0.757
2005 Moberg KH, Schelble S, Burdick SK, Hariharan IK. Mutations in erupted, the Drosophila ortholog of mammalian tumor susceptibility gene 101, elicit non-cell-autonomous overgrowth. Developmental Cell. 9: 699-710. PMID 16256744 DOI: 10.1016/j.devcel.2005.09.018  0.735
2005 Delalle I, Pfleger CM, Buff E, Lueras P, Hariharan IK. Mutations in the Drosophila orthologs of the F-actin capping protein alpha- and beta-subunits cause actin accumulation and subsequent retinal degeneration. Genetics. 171: 1757-65. PMID 16143599 DOI: 10.1534/Genetics.105.049213  0.762
2005 Reis T, Hariharan IK. Melting fat away in flies. Cell Metabolism. 2: 82-4. PMID 16098825 DOI: 10.1016/j.cmet.2005.08.002  0.634
2005 Kwak EL, Moberg KH, Wahrer DC, Quinn JE, Gilmore PM, Graham CA, Hariharan IK, Harkin DP, Haber DA, Bell DW. Infrequent mutations of Archipelago (hAGO, hCDC4, Fbw7) in primary ovarian cancer. Gynecologic Oncology. 98: 124-8. PMID 15913747 DOI: 10.1016/J.Ygyno.2005.04.007  0.634
2004 Moberg KH, Mukherjee A, Veraksa A, Artavanis-Tsakonas S, Hariharan IK. The Drosophila F box protein archipelago regulates dMyc protein levels in vivo. Current Biology : Cb. 14: 965-74. PMID 15182669 DOI: 10.1016/J.Cub.2004.04.040  0.717
2003 Moberg KH, Hariharan IK. Big things from a little RNA. Trends in Cell Biology. 13: 455-7. PMID 12946623 DOI: 10.1016/S0962-8924(03)00168-5  0.701
2003 Harvey KF, Pfleger CM, Hariharan IK. The Drosophila Mst ortholog, hippo, restricts growth and cell proliferation and promotes apoptosis. Cell. 114: 457-67. PMID 12941274 DOI: 10.1016/S0092-8674(03)00557-9  0.785
2002 Neufeld TP, Hariharan IK. Regulation of growth and cell proliferation during eye development. Results and Problems in Cell Differentiation. 37: 107-33. PMID 25707072 DOI: 10.1007/978-3-540-45398-7_8  0.644
2002 Tseng AS, Hariharan IK. An overexpression screen in Drosophila for genes that restrict growth or cell-cycle progression in the developing eye. Genetics. 162: 229-43. PMID 12242236  0.319
2002 Tapon N, Harvey KF, Bell DW, Wahrer DC, Schiripo TA, Haber D, Hariharan IK. salvador Promotes both cell cycle exit and apoptosis in Drosophila and is mutated in human cancer cell lines. Cell. 110: 467-78. PMID 12202036 DOI: 10.1016/S0092-8674(02)00824-3  0.785
2001 Tapon N, Moberg KH, Hariharan IK. The coupling of cell growth to the cell cycle. Current Opinion in Cell Biology. 13: 731-7. PMID 11698190 DOI: 10.1016/S0955-0674(00)00284-2  0.781
2001 Moberg KH, Bell DW, Wahrer DC, Haber DA, Hariharan IK. Archipelago regulates Cyclin E levels in Drosophila and is mutated in human cancer cell lines. Nature. 413: 311-6. PMID 11565033 DOI: 10.1038/35095068  0.683
2001 Tapon N, Ito N, Dickson BJ, Treisman JE, Hariharan IK. The Drosophila tuberous sclerosis complex gene homologs restrict cell growth and cell proliferation. Cell. 105: 345-55. PMID 11348591 DOI: 10.1016/S0092-8674(01)00332-4  0.799
2000 Fortini ME, Skupski MP, Boguski MS, Hariharan IK. A survey of human disease gene counterparts in the Drosophila genome. The Journal of Cell Biology. 150: F23-30. PMID 10908582  0.55
2000 Rubin GM, Yandell MD, Wortman JR, Gabor Miklos GL, Nelson CR, Hariharan IK, Fortini ME, Li PW, Apweiler R, Fleischmann W, Cherry JM, Henikoff S, Skupski MP, Misra S, Ashburner M, et al. Comparative genomics of the eukaryotes. Science (New York, N.Y.). 287: 2204-15. PMID 10731134 DOI: 10.1126/Science.287.5461.2204  0.729
1999 Asha H, de Ruiter ND, Wang MG, Hariharan IK. The Rap1 GTPase functions as a regulator of morphogenesis in vivo. The Embo Journal. 18: 605-15. PMID 9927420 DOI: 10.1093/emboj/18.3.605  0.429
1997 Li Q, Hariharan IK, Chen F, Huang Y, Fischer JA. Genetic interactions with Rap1 and Ras1 reveal a second function for the fat facets deubiquitinating enzyme in Drosophila eye development. Proceedings of the National Academy of Sciences of the United States of America. 94: 12515-20. PMID 9356481 DOI: 10.1073/Pnas.94.23.12515  0.636
1997 Chen F, Barkett M, Ram KT, Quintanilla A, Hariharan IK. Biological characterization of Drosophila Rapgap1, a GTPase activating protein for Rap1. Proceedings of the National Academy of Sciences of the United States of America. 94: 12485-90. PMID 9356476  0.35
1997 The I, Hannigan GE, Cowley GS, Reginald S, Zhong Y, Gusella JF, Hariharan IK, Bernards A. Rescue of a Drosophila NF1 mutant phenotype by protein kinase A. Science (New York, N.Y.). 276: 791-4. PMID 9115203 DOI: 10.1126/science.276.5313.791  0.34
1996 de Nooij JC, Letendre MA, Hariharan IK. A cyclin-dependent kinase inhibitor, Dacapo, is necessary for timely exit from the cell cycle during Drosophila embryogenesis. Cell. 87: 1237-47. PMID 8980230 DOI: 10.1016/S0092-8674(00)81819-X  0.351
1995 Hariharan IK, Hu KQ, Asha H, Quintanilla A, Ezzell RM, Settleman J. Characterization of rho GTPase family homologues in Drosophila melanogaster: overexpressing Rho1 in retinal cells causes a late developmental defect. The Embo Journal. 14: 292-302. PMID 7835340  0.399
1995 de Nooij JC, Hariharan IK. Uncoupling cell fate determination from patterned cell division in the Drosophila eye. Science (New York, N.Y.). 270: 983-5. PMID 7481802  0.338
1993 Heberlein U, Hariharan IK, Rubin GM. Star is required for neuronal differentiation in the Drosophila retina and displays dosage-sensitive interactions with Ras1. Developmental Biology. 160: 51-63. PMID 8224548 DOI: 10.1006/dbio.1993.1285  0.665
1991 Hariharan IK, Carthew RW, Rubin GM. The Drosophila roughened mutation: activation of a rap homolog disrupts eye development and interferes with cell determination. Cell. 67: 717-22. PMID 1934069 DOI: 10.1016/0092-8674(91)90066-8  0.717
1991 Hariharan IK, Chuang PT, Rubin GM. Cloning and characterization of a receptor-class phosphotyrosine phosphatase gene expressed on central nervous system axons in Drosophila melanogaster. Proceedings of the National Academy of Sciences of the United States of America. 88: 11266-70. PMID 1662390 DOI: 10.1073/Pnas.88.24.11266  0.433
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