Daniel L. Marks - Publications

Affiliations: 
2008-2013 Pediatric Endocrinology Oregon Health&Science University, Portland, OR, United States 

107 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Michaelis KA, Norgard MA, Zhu X, Levasseur PR, Sivagnanam S, Liudahl SM, Burfeind KG, Olson B, Pelz KR, Ramos DMA, Maurer HC, Olive KP, Coussens LM, Morgan TK, Marks DL. Publisher Correction: The TLR7/8 agonist R848 remodels tumor and host responses to promote survival in pancreatic cancer. Nature Communications. 10: 5257. PMID 31729370 DOI: 10.1038/s41467-019-13151-z  0.36
2019 Michaelis KA, Norgard MA, Zhu X, Levasseur PR, Sivagnanam S, Liudahl SM, Burfeind KG, Olson B, Pelz KR, Angeles Ramos DM, Maurer HC, Olive KP, Coussens LM, Morgan TK, Marks DL. The TLR7/8 agonist R848 remodels tumor and host responses to promote survival in pancreatic cancer. Nature Communications. 10: 4682. PMID 31615993 DOI: 10.1038/s41467-019-12657-w  0.36
2019 Michaelis KA, Norgard MA, Levasseur PR, Olson B, Burfeind KG, Buenafe AC, Zhu X, Jeng S, McWeeney SK, Marks DL. Persistent Toll-like receptor 7 stimulation induces behavioral and molecular innate immune tolerance. Brain, Behavior, and Immunity. PMID 31499172 DOI: 10.1016/j.bbi.2019.09.004  0.36
2019 Doslikova B, Tchir D, McKinty A, Zhu X, Marks DL, Baracos VE, Colmers WF. Convergent neuronal projections from paraventricular nucleus, parabrachial nucleus and brainstem onto gastrocnemius muscle, white and brown adipose tissue in male rats. The Journal of Comparative Neurology. PMID 31045239 DOI: 10.1002/cne.24710  0.36
2019 Zhu X, Burfeind KG, Michaelis KA, Braun TP, Olson B, Pelz KR, Morgan TK, Marks DL. MyD88 signalling is critical in the development of pancreatic cancer cachexia. Journal of Cachexia, Sarcopenia and Muscle. PMID 30666818 DOI: 10.1002/jcsm.12377  0.36
2018 Schumann C, Nguyen DX, Norgard M, Bortnyak Y, Korzun T, Chan S, Lorenz AS, Moses AS, Albarqi HA, Wong L, Michaelis K, Zhu X, Alani AWG, Taratula OR, Krasnow S, ... Marks DL, et al. Increasing lean muscle mass in mice via nanoparticle-mediated hepatic delivery of follistatin mRNA. Theranostics. 8: 5276-5288. PMID 30555546 DOI: 10.7150/thno.27847  0.36
2018 Burfeind KG, Zhu X, Levasseur PR, Michaelis KA, Norgard MA, Marks DL. "TRIF is a key inflammatory mediator of acute sickness behavior and cancer cachexia". Brain, Behavior, and Immunity. PMID 29852290 DOI: 10.1016/j.bbi.2018.05.021  0.36
2017 Michaelis KA, Zhu X, Burfeind KG, Krasnow SM, Levasseur PR, Morgan TK, Marks DL. Establishment and characterization of a novel murine model of pancreatic cancer cachexia. Journal of Cachexia, Sarcopenia and Muscle. PMID 28730707 DOI: 10.1002/jcsm.12225  0.36
2016 Kram DE, Krasnow SM, Levasseur PR, Zhu X, Stork LC, Marks DL. Dexamethasone Chemotherapy Does Not Disrupt Orexin Signaling. Plos One. 11: e0168731. PMID 27997622 DOI: 10.1371/journal.pone.0168731  0.36
2016 Burfeind KG, Yadav V, Marks DL. Hypothalamic Dysfunction and Multiple Sclerosis: Implications for Fatigue and Weight Dysregulation. Current Neurology and Neuroscience Reports. 16: 98. PMID 27662896 DOI: 10.1007/s11910-016-0700-3  0.36
2016 Zhu X, Levasseur PR, Michaelis KA, Burfeind KG, Marks DL. A distinct brain pathway links viral RNA exposure to sickness behavior. Scientific Reports. 6: 29885. PMID 27435819 DOI: 10.1038/srep29885  0.36
2015 Tian Q, Smart JL, Clement JH, Wang Y, Derkatch A, Schubert H, Danilchik MV, Marks DL, Fedorov LM. RHEB1 expression in embryonic and postnatal mouse. Histochemistry and Cell Biology. PMID 26708151 DOI: 10.1007/s00418-015-1394-3  0.36
2015 Luchtman DW, Chee MJ, Doslikova B, Marks DL, Baracos VE, Colmers WF. Defense of Elevated Body Weight Setpoint in Diet-Induced Obese Rats on Low Energy Diet Is Mediated by Loss of Melanocortin Sensitivity in the Paraventricular Hypothalamic Nucleus. Plos One. 10: e0139462. PMID 26444289 DOI: 10.1371/journal.pone.0139462  0.36
2015 Dwarkasing JT, Marks DL, Witkamp RF, van Norren K. Hypothalamic inflammation and food intake regulation during chronic illness. Peptides. PMID 26158772 DOI: 10.1016/j.peptides.2015.06.011  0.36
2015 Braun TP, Marks DL. The regulation of muscle mass by endogenous glucocorticoids. Frontiers in Physiology. 6: 12. PMID 25691871 DOI: 10.3389/fphys.2015.00012  0.36
2015 Kamimae-Lanning AN, Krasnow SM, Goloviznina NA, Zhu X, Roth-Carter QR, Levasseur PR, Jeng S, McWeeney SK, Kurre P, Marks DL. Maternal high-fat diet and obesity compromise fetal hematopoiesis. Molecular Metabolism. 4: 25-38. PMID 25685687 DOI: 10.1016/j.molmet.2014.11.001  0.36
2015 Connelly KJ, Larson EA, Marks DL, Klein RF. Neonatal estrogen exposure results in biphasic age-dependent effects on the skeletal development of male mice. Endocrinology. 156: 193-202. PMID 25330099 DOI: 10.1210/en.2014-1324  0.36
2014 Braun TP, Szumowski M, Levasseur PR, Grossberg AJ, Zhu X, Agarwal A, Marks DL. Muscle atrophy in response to cytotoxic chemotherapy is dependent on intact glucocorticoid signaling in skeletal muscle. Plos One. 9: e106489. PMID 25254959 DOI: 10.1371/journal.pone.0106489  0.36
2014 O'Rourke RW, Meyer KA, Neeley CK, Gaston GD, Sekhri P, Szumowski M, Zamarron B, Lumeng CN, Marks DL. Systemic NK cell ablation attenuates intra-abdominal adipose tissue macrophage infiltration in murine obesity. Obesity (Silver Spring, Md.). 22: 2109-14. PMID 24962029 DOI: 10.1002/oby.20823  0.36
2014 Zuloaga KL, Krasnow SM, Zhu X, Zhang W, Jouihan SA, Shangraw RE, Alkayed NJ, Marks DL. Mechanism of protection by soluble epoxide hydrolase inhibition in type 2 diabetic stroke. Plos One. 9: e97529. PMID 24824753 DOI: 10.1371/journal.pone.0097529  0.36
2014 Weymann KB, Wood LJ, Zhu X, Marks DL. A role for orexin in cytotoxic chemotherapy-induced fatigue. Brain, Behavior, and Immunity. 37: 84-94. PMID 24216337 DOI: 10.1016/j.bbi.2013.11.003  0.36
2013 O'Rourke RW, Gaston GD, Meyer KA, White AE, Marks DL. Adipose tissue NK cells manifest an activated phenotype in human obesity. Metabolism: Clinical and Experimental. 62: 1557-61. PMID 24012153 DOI: 10.1016/j.metabol.2013.07.011  0.36
2013 O'Rourke RW, Meyer KA, Gaston G, White AE, Lumeng CN, Marks DL. Hexosamine biosynthesis is a possible mechanism underlying hypoxia's effects on lipid metabolism in human adipocytes. Plos One. 8: e71165. PMID 23967162 DOI: 10.1371/journal.pone.0071165  0.36
2013 Jouihan SA, Zuloaga KL, Zhang W, Shangraw RE, Krasnow SM, Marks DL, Alkayed NJ. Role of soluble epoxide hydrolase in exacerbation of stroke by streptozotocin-induced type 1 diabetes mellitus. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 33: 1650-6. PMID 23899929 DOI: 10.1038/jcbfm.2013.130  0.36
2013 Braun TP, Grossberg AJ, Krasnow SM, Levasseur PR, Szumowski M, Zhu XX, Maxson JE, Knoll JG, Barnes AP, Marks DL. Cancer- and endotoxin-induced cachexia require intact glucocorticoid signaling in skeletal muscle. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 27: 3572-82. PMID 23733748 DOI: 10.1096/fj.13-230375  0.36
2013 Potter GB, Santos M, Davisson MT, Rowitch DH, Marks DL, Bongarzone ER, Petryniak MA. Missense mutation in mouse GALC mimics human gene defect and offers new insights into Krabbe disease. Human Molecular Genetics. 22: 3397-414. PMID 23620143 DOI: 10.1093/hmg/ddt190  0.36
2013 Nicol LE, Grant WF, Grant WR, Comstock SM, Nguyen ML, Smith MS, Grove KL, Marks DL. Pancreatic inflammation and increased islet macrophages in insulin-resistant juvenile primates. The Journal of Endocrinology. 217: 207-13. PMID 23420316 DOI: 10.1530/JOE-12-0424  0.36
2013 Scott-Drechsel DE, Rugonyi S, Marks DL, Thornburg KL, Hinds MT. Hyperglycemia slows embryonic growth and suppresses cell cycle via cyclin D1 and p21. Diabetes. 62: 234-42. PMID 23193186 DOI: 10.2337/db12-0161  0.36
2013 Kievit P, Halem H, Marks DL, Dong JZ, Glavas MM, Sinnayah P, Pranger L, Cowley MA, Grove KL, Culler MD. Chronic treatment with a melanocortin-4 receptor agonist causes weight loss, reduces insulin resistance, and improves cardiovascular function in diet-induced obese rhesus macaques. Diabetes. 62: 490-7. PMID 23048186 DOI: 10.2337/db12-0598  0.36
2012 Grant WF, Nicol LE, Thorn SR, Grove KL, Friedman JE, Marks DL. Perinatal exposure to a high-fat diet is associated with reduced hepatic sympathetic innervation in one-year old male Japanese macaques. Plos One. 7: e48119. PMID 23118937 DOI: 10.1371/journal.pone.0048119  0.36
2012 Zhu X, Krasnow SM, Roth-Carter QR, Levasseur PR, Braun TP, Grossberg AJ, Marks DL. Hypothalamic signaling in anorexia induced by indispensable amino acid deficiency. American Journal of Physiology. Endocrinology and Metabolism. 303: E1446-58. PMID 23047987 DOI: 10.1152/ajpendo.00427.2012  0.36
2012 Braun TP, Grossberg AJ, Veleva-Rotse BO, Maxson JE, Szumowski M, Barnes AP, Marks DL. Expression of myeloid differentiation factor 88 in neurons is not requisite for the induction of sickness behavior by interleukin-1β. Journal of Neuroinflammation. 9: 229. PMID 23031643 DOI: 10.1186/1742-2094-9-229  0.36
2012 Braun TP, Orwoll B, Zhu X, Levasseur PR, Szumowski M, Nguyen ML, Bouxsein ML, Klein RF, Marks DL. Regulation of lean mass, bone mass, and exercise tolerance by the central melanocortin system. Plos One. 7: e42183. PMID 22848742 DOI: 10.1371/journal.pone.0042183  0.36
2012 Tan BH, Fladvad T, Braun TP, Vigano A, Strasser F, Deans DA, Skipworth RJ, Solheim TS, Damaraju S, Ross JA, Kaasa S, Marks DL, Baracos VE, Skorpen F, Fearon KC, et al. P-selectin genotype is associated with the development of cancer cachexia. Embo Molecular Medicine. 4: 462-71. PMID 22473907 DOI: 10.1002/emmm.201200231  0.36
2012 O'Rourke RW, White AE, Metcalf MD, Winters BR, Diggs BS, Zhu X, Marks DL. Systemic inflammation and insulin sensitivity in obese IFN-γ knockout mice. Metabolism: Clinical and Experimental. 61: 1152-61. PMID 22386937 DOI: 10.1016/j.metabol.2012.01.018  0.36
2011 Braun TP, Zhu X, Szumowski M, Scott GD, Grossberg AJ, Levasseur PR, Graham K, Khan S, Damaraju S, Colmers WF, Baracos VE, Marks DL. Central nervous system inflammation induces muscle atrophy via activation of the hypothalamic-pituitary-adrenal axis. The Journal of Experimental Medicine. 208: 2449-63. PMID 22084407 DOI: 10.1084/jem.20111020  0.36
2011 Begriche K, Levasseur PR, Zhang J, Rossi J, Skorupa D, Solt LA, Young B, Burris TP, Marks DL, Mynatt RL, Butler AA. Genetic dissection of the functions of the melanocortin-3 receptor, a seven-transmembrane G-protein-coupled receptor, suggests roles for central and peripheral receptors in energy homeostasis. The Journal of Biological Chemistry. 286: 40771-81. PMID 21984834 DOI: 10.1074/jbc.M111.278374  0.36
2011 Dallmann R, Weyermann P, Anklin C, Boroff M, Bray-French K, Cardel B, Courdier-Fruh I, Deppe H, Dubach-Powell J, Erb M, Haefeli RH, Henneböhle M, Herzner H, Hufschmid M, Marks DL, et al. The orally active melanocortin-4 receptor antagonist BL-6020/979: a promising candidate for the treatment of cancer cachexia. Journal of Cachexia, Sarcopenia and Muscle. 2: 163-174. PMID 21966642 DOI: 10.1007/s13539-011-0039-1  0.36
2011 Krasnow SM, Nguyen ML, Marks DL. Increased maternal fat consumption during pregnancy alters body composition in neonatal mice. American Journal of Physiology. Endocrinology and Metabolism. 301: E1243-53. PMID 21900122 DOI: 10.1152/ajpendo.00261.2011  0.36
2011 Grossberg AJ, Zhu X, Leinninger GM, Levasseur PR, Braun TP, Myers MG, Marks DL. Inflammation-induced lethargy is mediated by suppression of orexin neuron activity. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 31: 11376-86. PMID 21813697 DOI: 10.1523/JNEUROSCI.2311-11.2011  0.36
2011 Braun TP, Marks DL. Hypothalamic regulation of muscle metabolism. Current Opinion in Clinical Nutrition and Metabolic Care. 14: 237-42. PMID 21502918 DOI: 10.1097/MCO.0b013e328345bbcd  0.36
2011 O'Rourke RW, White AE, Metcalf MD, Olivas AS, Mitra P, Larison WG, Cheang EC, Varlamov O, Corless CL, Roberts CT, Marks DL. Hypoxia-induced inflammatory cytokine secretion in human adipose tissue stromovascular cells. Diabetologia. 54: 1480-90. PMID 21400042 DOI: 10.1007/s00125-011-2103-y  0.36
2011 Grant WF, Gillingham MB, Batra AK, Fewkes NM, Comstock SM, Takahashi D, Braun TP, Grove KL, Friedman JE, Marks DL. Maternal high fat diet is associated with decreased plasma n-3 fatty acids and fetal hepatic apoptosis in nonhuman primates. Plos One. 6: e17261. PMID 21364873 DOI: 10.1371/journal.pone.0017261  0.36
2011 Sampath H, Batra AK, Vartanian V, Carmical JR, Prusak D, King IB, Lowell B, Earley LF, Wood TG, Marks DL, McCullough AK, R Stephen L. Variable penetrance of metabolic phenotypes and development of high-fat diet-induced adiposity in NEIL1-deficient mice. American Journal of Physiology. Endocrinology and Metabolism. 300: E724-34. PMID 21285402 DOI: 10.1152/ajpendo.00387.2010  0.36
2010 Braun TP, Marks DL. Pathophysiology and treatment of inflammatory anorexia in chronic disease. Journal of Cachexia, Sarcopenia and Muscle. 1: 135-145. PMID 21475703 DOI: 10.1007/s13539-010-0015-1  0.36
2010 Hosoyama T, Nishijo K, Garcia MM, Schaffer BS, Ohshima-Hosoyama S, Prajapati SI, Davis MD, Grant WF, Scheithauer BW, Marks DL, Rubin BP, Keller C. A Postnatal Pax7 Progenitor Gives Rise to Pituitary Adenomas. Genes & Cancer. 1: 388-402. PMID 20811506 DOI: 10.1177/1947601910370979  0.36
2010 Krasnow SM, Marks DL. Neuropeptides in the pathophysiology and treatment of cachexia. Current Opinion in Supportive and Palliative Care. 4: 266-71. PMID 20733497 DOI: 10.1097/SPC.0b013e32833e48e7  0.36
2010 Scarlett JM, Bowe DD, Zhu X, Batra AK, Grant WF, Marks DL. Genetic and pharmacologic blockade of central melanocortin signaling attenuates cardiac cachexia in rodent models of heart failure. The Journal of Endocrinology. 206: 121-30. PMID 20371568 DOI: 10.1677/JOE-09-0397  0.36
2010 Grossberg AJ, Scarlett JM, Marks DL. Hypothalamic mechanisms in cachexia. Physiology & Behavior. 100: 478-89. PMID 20346963 DOI: 10.1016/j.physbeh.2010.03.011  0.36
2010 Grayson BE, Levasseur PR, Williams SM, Smith MS, Marks DL, Grove KL. Changes in melanocortin expression and inflammatory pathways in fetal offspring of nonhuman primates fed a high-fat diet. Endocrinology. 151: 1622-32. PMID 20176722 DOI: 10.1210/en.2009-1019  0.36
2010 Grossberg AJ, Scarlett JM, Zhu X, Bowe DD, Batra AK, Braun TP, Marks DL. Arcuate nucleus proopiomelanocortin neurons mediate the acute anorectic actions of leukemia inhibitory factor via gp130. Endocrinology. 151: 606-16. PMID 20016025 DOI: 10.1210/en.2009-1135  0.36
2010 Barazzoni R, Zhu X, Deboer M, Datta R, Culler MD, Zanetti M, Guarnieri G, Marks DL. Combined effects of ghrelin and higher food intake enhance skeletal muscle mitochondrial oxidative capacity and AKT phosphorylation in rats with chronic kidney disease. Kidney International. 77: 23-8. PMID 19890275 DOI: 10.1038/ki.2009.411  0.36
2009 O'Rourke RW, Metcalf MD, White AE, Madala A, Winters BR, Maizlin II, Jobe BA, Roberts CT, Slifka MK, Marks DL. Depot-specific differences in inflammatory mediators and a role for NK cells and IFN-gamma in inflammation in human adipose tissue. International Journal of Obesity (2005). 33: 978-90. PMID 19564875 DOI: 10.1038/ijo.2009.133  0.36
2009 Lowas S, Malempati S, Marks D. Body mass index predicts insulin resistance in survivors of pediatric acute lymphoblastic leukemia Pediatric Blood and Cancer. 53: 58-63. PMID 19340854 DOI: 10.1002/pbc.21993  0.36
2009 Lowas SR, Marks D, Malempati S. Prevalence of transient hyperglycemia during induction chemotherapy for pediatric acute lymphoblastic leukemia Pediatric Blood and Cancer. 52: 814-818. PMID 19260096 DOI: 10.1002/pbc.21980  0.36
2009 DeBoer MD, Scarlett JM, Levasseur PR, Grant WF, Marks DL. Administration of IL-1beta to the 4th ventricle causes anorexia that is blocked by agouti-related peptide and that coincides with activation of tyrosine-hydroxylase neurons in the nucleus of the solitary tract. Peptides. 30: 210-8. PMID 19028534 DOI: 10.1016/j.peptides.2008.10.019  0.36
2008 Evans WJ, Morley JE, Argilés J, Bales C, Baracos V, Guttridge D, Jatoi A, Kalantar-Zadeh K, Lochs H, Mantovani G, Marks D, Mitch WE, Muscaritoli M, Najand A, Ponikowski P, et al. Cachexia: a new definition. Clinical Nutrition (Edinburgh, Scotland). 27: 793-9. PMID 18718696 DOI: 10.1016/j.clnu.2008.06.013  0.36
2008 Laviano A, Inui A, Marks DL, Meguid MM, Pichard C, Rossi Fanelli F, Seelaender M. Neural control of the anorexia-cachexia syndrome. American Journal of Physiology. Endocrinology and Metabolism. 295: E1000-8. PMID 18713954 DOI: 10.1152/ajpendo.90252.2008  0.36
2008 Scarlett JM, Zhu X, Enriori PJ, Bowe DD, Batra AK, Levasseur PR, Grant WF, Meguid MM, Cowley MA, Marks DL. Regulation of agouti-related protein messenger ribonucleic acid transcription and peptide secretion by acute and chronic inflammation. Endocrinology. 149: 4837-45. PMID 18583425 DOI: 10.1210/en.2007-1680  0.36
2008 Wayman GA, Davare M, Ando H, Fortin D, Varlamova O, Cheng HY, Marks D, Obrietan K, Soderling TR, Goodman RH, Impey S. An activity-regulated microRNA controls dendritic plasticity by down-regulating p250GAP. Proceedings of the National Academy of Sciences of the United States of America. 105: 9093-8. PMID 18577589 DOI: 10.1073/pnas.0803072105  0.36
2008 Sartin JL, Marks DL, McMahon CD, Daniel JA, Levasseur P, Wagner CG, Whitlock BK, Steele BP. Central role of the melanocortin-4 receptors in appetite regulation after endotoxin. Journal of Animal Science. 86: 2557-67. PMID 18502874 DOI: 10.2527/jas.2008-0916  0.36
2008 Chen C, Tucci FC, Jiang W, Tran JA, Fleck BA, Hoare SR, Wen J, Chen T, Johns M, Markison S, Foster AC, Marinkovic D, Chen CW, Arellano M, Harman J, ... ... Marks D, et al. Pharmacological and pharmacokinetic characterization of 2-piperazine-alpha-isopropyl benzylamine derivatives as melanocortin-4 receptor antagonists. Bioorganic & Medicinal Chemistry. 16: 5606-18. PMID 18417348 DOI: 10.1016/j.bmc.2008.03.072  0.36
2008 Madison LD, Scarlett JM, Levasseur P, Zhu X, Newcomb K, Batra A, Bowe D, Marks DL. Prostacyclin signaling regulates circulating ghrelin during acute inflammation. The Journal of Endocrinology. 196: 263-73. PMID 18252949 DOI: 10.1677/JOE-07-0478  0.36
2008 Deboer MD, Zhu X, Levasseur PR, Inui A, Hu Z, Han G, Mitch WE, Taylor JE, Halem HA, Dong JZ, Datta R, Culler MD, Marks DL. Ghrelin treatment of chronic kidney disease: improvements in lean body mass and cytokine profile. Endocrinology. 149: 827-35. PMID 18039782 DOI: 10.1210/en.2007-1046  0.36
2007 Fletcher AL, Marks DL. Central mechanisms controlling appetite and food intake in a cancer setting: an update. Current Opinion in Supportive and Palliative Care. 1: 306-11. PMID 18685380 DOI: 10.1097/SPC.0b013e3282f14c4e  0.36
2007 Appleyard SM, Marks D, Kobayashi K, Okano H, Low MJ, Andresen MC. Visceral afferents directly activate catecholamine neurons in the solitary tract nucleus. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 27: 13292-302. PMID 18045923 DOI: 10.1523/JNEUROSCI.3502-07.2007  0.36
2007 Tran JA, Jiang W, Tucci FC, Fleck BA, Wen J, Sai Y, Madan A, Ta KC, Markison S, Foster AC, Hoare SR, Marks D, Harman J, Chen CW, Arellano M, et al. Design, synthesis, in vitro, and in vivo characterization of phenylpiperazines and pyridinylpiperazines as potent and selective antagonists of the melanocortin-4 receptor Journal of Medicinal Chemistry. 50: 6356-6366. PMID 17994683 DOI: 10.1021/jm701137s  0.36
2007 Ellacott KL, Murphy JG, Marks DL, Cone RD. Obesity-induced inflammation in white adipose tissue is attenuated by loss of melanocortin-3 receptor signaling. Endocrinology. 148: 6186-94. PMID 17901224 DOI: 10.1210/en.2007-0699  0.36
2007 Cheung WW, Kuo HJ, Markison S, Chen C, Foster AC, Marks DL, Mak RH. Peripheral administration of the melanocortin-4 receptor antagonist NBI-12i ameliorates uremia-associated cachexia in mice. Journal of the American Society of Nephrology : Jasn. 18: 2517-24. PMID 17687077 DOI: 10.1681/ASN.2006091024  0.36
2007 Tran JA, Tucci FC, Jiang W, Marinkovic D, Chen CW, Arellano M, Markison S, Fleck BA, Wen J, White NS, Pontillo J, Saunders J, Marks D, Hoare SR, Madan A, et al. Pyrrolidinones as orally bioavailable antagonists of the human melanocortin-4 receptor with anti-cachectic activity. Bioorganic & Medicinal Chemistry. 15: 5166-76. PMID 17544282 DOI: 10.1016/j.bmc.2007.05.026  0.36
2007 Scarlett JM, Jobst EE, Enriori PJ, Bowe DD, Batra AK, Grant WF, Cowley MA, Marks DL. Regulation of central melanocortin signaling by interleukin-1 beta. Endocrinology. 148: 4217-25. PMID 17525125 DOI: 10.1210/en.2007-0017  0.36
2007 DeBoer MD, Zhu XX, Levasseur P, Meguid MM, Suzuki S, Inui A, Taylor JE, Halem HA, Dong JZ, Datta R, Culler MD, Marks DL. Ghrelin treatment causes increased food intake and retention of lean body mass in a rat model of cancer cachexia. Endocrinology. 148: 3004-12. PMID 17347304 DOI: 10.1210/en.2007-0016  0.36
2007 Le D, Marks D, Lyle E, Corless CL, Diggs BS, Jobe BA, Kay T, Deveney CW, Wolfe BM, Roberts CT, O'Rourke RW. Serum leptin levels, hepatic leptin receptor transcription, and clinical predictors of non-alcoholic steatohepatitis in obese bariatric surgery patients Surgical Endoscopy and Other Interventional Techniques. 21: 1593-1599. PMID 17294310 DOI: 10.1007/s00464-006-9185-5  0.36
2006 O'Rourke RW, Kay T, Lyle EA, Traxler SA, Deveney CW, Jobe BA, Roberts CT, Marks D, Rosenbaum JT. Alterations in peripheral blood lymphocyte cytokine expression in obesity Clinical and Experimental Immunology. 146: 39-46. PMID 16968396 DOI: 10.1111/j.1365-2249.2006.03186.x  0.36
2006 Mak RH, Cheung W, Cone RD, Marks DL. Mechanisms of disease: Cytokine and adipokine signaling in uremic cachexia. Nature Clinical Practice. Nephrology. 2: 527-34. PMID 16941045 DOI: 10.1038/ncpneph0273  0.36
2006 DeBoer MD, Marks DL. Therapy insight: Use of melanocortin antagonists in the treatment of cachexia in chronic disease. Nature Clinical Practice. Endocrinology & Metabolism. 2: 459-66. PMID 16932335 DOI: 10.1038/ncpendmet0221  0.36
2006 Wayman GA, Impey S, Marks D, Saneyoshi T, Grant WF, Derkach V, Soderling TR. Activity-dependent dendritic arborization mediated by CaM-kinase I activation and enhanced CREB-dependent transcription of Wnt-2. Neuron. 50: 897-909. PMID 16772171 DOI: 10.1016/j.neuron.2006.05.008  0.36
2006 Deboer MD, Marks DL. Cachexia: lessons from melanocortin antagonism. Trends in Endocrinology and Metabolism: Tem. 17: 199-204. PMID 16750633 DOI: 10.1016/j.tem.2006.05.005  0.36
2006 Madison LD, Marks DL. Anticatabolic properties of melanocortin-4 receptor antagonists. Current Opinion in Clinical Nutrition and Metabolic Care. 9: 196-200. PMID 16607116 DOI: 10.1097/01.mco.0000222099.36632.81  0.36
2006 Mak RH, Cheung W, Cone RD, Marks DL. Leptin and inflammation-associated cachexia in chronic kidney disease. Kidney International. 69: 794-7. PMID 16518340 DOI: 10.1038/sj.ki.5000182  0.36
2006 Marks DL, Hruby V, Brookhart G, Cone RD. The regulation of food intake by selective stimulation of the type 3 melanocortin receptor (MC3R). Peptides. 27: 259-64. PMID 16274853 DOI: 10.1016/j.peptides.2005.01.025  0.36
2005 Scarlett JM, Marks DL. The use of melanocortin antagonists in cachexia of chronic disease Expert Opinion On Investigational Drugs. 14: 1233-1240. PMID 16185165 DOI: 10.1517/13543784.14.10.1233  0.36
2005 Cheung W, Yu PX, Little BM, Cone RD, Marks DL, Mak RH. Role of leptin and melanocortin signaling in uremia-associated cachexia. The Journal of Clinical Investigation. 115: 1659-65. PMID 15931394 DOI: 10.1172/JCI22521  0.36
2005 Sartin JL, Wagner CG, Marks DL, Daniel JA, McMahon CD, Obese FY, Partridge C. Melanocortin-4 receptor in sheep: A potential site for therapeutic intervention in disease models Domestic Animal Endocrinology. 29: 446-455. PMID 15919173 DOI: 10.1016/j.domaniend.2005.02.027  0.36
2005 Foster AC, Chen C, Markison S, Marks DL. MC4 receptor antagonists: a potential treatment for cachexia. Idrugs : the Investigational Drugs Journal. 8: 314-9. PMID 15800806  0.36
2005 Markison S, Foster AC, Chen C, Brookhart GB, Hesse A, Hoare SR, Fleck BA, Brown BT, Marks DL. The regulation of feeding and metabolic rate and the prevention of murine cancer cachexia with a small-molecule melanocortin-4 receptor antagonist. Endocrinology. 146: 2766-73. PMID 15774557 DOI: 10.1210/en.2005-0142  0.36
2005 Mak RH, Cheung W, Cone RD, Marks DL. Orexigenic and anorexigenic mechanisms in the control of nutrition in chronic kidney disease. Pediatric Nephrology (Berlin, Germany). 20: 427-31. PMID 15662537 DOI: 10.1007/s00467-004-1789-1  0.36
2004 Wagner CG, McMahon CD, Marks DL, Daniel JA, Steele B, Sartin JL. A role for agouti-related protein in appetite regulation in a species with continuous nutrient delivery Neuroendocrinology. 80: 210-218. PMID 15604600 DOI: 10.1159/000082735  0.36
2004 Fekete C, Marks DL, Sarkar S, Emerson CH, Rand WM, Cone RD, Lechan RM. Effect of Agouti-related protein in regulation of the hypothalamic-pituitary-thyroid axis in the melanocortin 4 receptor knockout mouse. Endocrinology. 145: 4816-21. PMID 15256492 DOI: 10.1210/en.2004-0476  0.36
2004 Ramos EJ, Suzuki S, Marks D, Inui A, Asakawa A, Meguid MM. Cancer anorexia-cachexia syndrome: cytokines and neuropeptides. Current Opinion in Clinical Nutrition and Metabolic Care. 7: 427-34. PMID 15192446 DOI: 10.1097/01.mco.0000134363.53782.cb  0.36
2004 Marks DL, Boucher N, Lanouette CM, Pérusse L, Brookhart G, Comuzzie AG, Chagnon YC, Cone RD. Ala67Thr polymorphism in the Agouti-related peptide gene is associated with inherited leanness in humans. American Journal of Medical Genetics. Part A. 126: 267-71. PMID 15054840 DOI: 10.1002/ajmg.a.20600  0.36
2003 Marks D, Cone RD. The role of the melanocortin-3 receptor in cachexia. Annals of the New York Academy of Sciences. 994: 258-66. PMID 12851324  0.36
2003 Marks DL, Butler AA, Turner R, Brookhart G, Cone RD. Differential role of melanocortin receptor subtypes in cachexia. Endocrinology. 144: 1513-23. PMID 12639936 DOI: 10.1210/en.2002-221099  0.36
2002 Marks DL, Butler AA, Cone RD. Melanocortin pathway: animal models of obesity and disease. Annales D'Endocrinologie. 63: 121-4. PMID 11994674  0.36
2001 Cone RD, Cowley MA, Butler AA, Fan W, Marks DL, Low MJ. The arcuate nucleus as a conduit for diverse signals relevant to energy homeostasis. International Journal of Obesity and Related Metabolic Disorders : Journal of the International Association For the Study of Obesity. 25: S63-7. PMID 11840218 DOI: 10.1038/sj.ijo.0801913  0.36
2001 Butler AA, Marks DL, Fan W, Kuhn CM, Bartolome M, Cone RD. Melanocortin-4 receptor is required for acute homeostatic responses to increased dietary fat. Nature Neuroscience. 4: 605-11. PMID 11369941 DOI: 10.1038/88423  0.36
2001 Marks DL, Ling N, Cone RD. Role of the central melanocortin system in cachexia. Cancer Research. 61: 1432-8. PMID 11245447  0.36
2001 Marks DL, Cone RD. Central melanocortins and the regulation of weight during acute and chronic disease. Recent Progress in Hormone Research. 56: 359-75. PMID 11237221 DOI: 10.1210/rp.56.1.359  0.36
2000 Fan W, Dinulescu DM, Butler AA, Zhou J, Marks DL, Cone RD. The central melanocortin system can directly regulate serum insulin levels. Endocrinology. 141: 3072-9. PMID 10965876 DOI: 10.1210/endo.141.9.7665  0.36
1996 Rossmanith WG, Marks DL, Clifton DK, Steiner RA. Induction of galanin mRNA in GnRH neurons by estradiol and its facilitation by progesterone Journal of Neuroendocrinology. 8: 185-191. PMID 8730652  0.36
1996 Rossmamth WG, Marks DL, Steiner RA, Clifton DK. Inhibition of steroid-induced galanin mRNA expression in GnRH neurons by specific NMDA-receptor blockade Journal of Neuroendocrinology. 8: 179-184. PMID 8730651  0.36
1994 Rossmanith WG, Marks DL, Clifton DK, Steiner RA. Induction of galanin gene expression in gonadotropin-releasing hormone neurons with puberty in the rat Endocrinology. 135: 1401-1408. PMID 7523097 DOI: 10.1210/en.135.4.1401  0.36
1994 Marks DL, Lent KL, Rossmanith WG, Clifton DK, Steiner RA. Activation-dependent regulation of galanin gene expression in gonadotropin-releasing hormone neurons in the female rat Endocrinology. 134: 1991-1998. PMID 7512492 DOI: 10.1210/en.134.5.1991  0.36
1993 Marks DL, Smith MS, Clifton DK, Steiner RA. Regulation of Gonadotropin-Releasing Hormone (GnRH) and galanin gene expression in GnRH neurons during lactation in the rat Endocrinology. 133: 1450-1458. PMID 7689958  0.36
1993 Marks DL, Smith MS, Vrontakis M, Clifton DK, Steiner RA. Regulation of galanin gene expression in gonadotropin-releasing hormone neurons during the estrous cycle of the rat Endocrinology. 132: 1836-1844. PMID 7681766  0.36
1992 Marks DL, Wiemann JN, Burton KA, Lent KL, Clifton DK, Steiner RA. Simultaneous visualization of two cellular mRNA species in individual neurons by use of a new double in Situ hybridization method Molecular and Cellular Neuroscience. 3: 395-405. DOI: 10.1016/1044-7431(92)90051-3  0.36
1990 Trevarrow B, Marks DL, Kimmel CB. Organization of hindbrain segments in the zebrafish embryo. Neuron. 4: 669-79. PMID 2344406 DOI: 10.1016/0896-6273(90)90194-K  0.36
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