| Year |
Citation |
Score |
| 2012 |
Hong C, Bradley MN, Rong X, Wang X, Wagner A, Grijalva V, Castellani LW, Salazar J, Realegeno S, Boyadjian R, Fogelman AM, Van Lenten BJ, Reddy ST, Lusis AJ, Tangirala RK, et al. LXRα is uniquely required for maximal reverse cholesterol transport and atheroprotection in ApoE-deficient mice Journal of Lipid Research. 53: 1126-1133. PMID 22454476 DOI: 10.1194/Jlr.M022061 |
0.396 |
|
| 2011 |
Hong C, Walczak R, Dhamko H, Bradley MN, Marathe C, Boyadjian R, Salazar JV, Tontonoz P. Constitutive activation of LXR in macrophages regulates metabolic and inflammatory gene expression: identification of ARL7 as a direct target. Journal of Lipid Research. 52: 531-9. PMID 21187453 DOI: 10.1194/Jlr.M010686 |
0.481 |
|
| 2010 |
Feig JE, Pineda-Torra I, Sanson M, Bradley MN, Vengrenyuk Y, Bogunovic D, Gautier EL, Rubinstein D, Hong C, Liu J, Wu C, van Rooijen N, Bhardwaj N, Garabedian M, Tontonoz P, et al. LXR promotes the maximal egress of monocyte-derived cells from mouse aortic plaques during atherosclerosis regression. The Journal of Clinical Investigation. 120: 4415-24. PMID 21041949 DOI: 10.1172/Jci38911 |
0.348 |
|
| 2010 |
Baur F, Beattie D, Beer D, Bentley D, Bradley M, Bruce I, Charlton SJ, Cuenoud B, Ernst R, Fairhurst RA, Faller B, Farr D, Keller T, Fozard JR, Fullerton J, et al. The identification of indacaterol as an ultralong-acting inhaled beta2-adrenoceptor agonist. Journal of Medicinal Chemistry. 53: 3675-84. PMID 20402514 DOI: 10.1021/Jm100068M |
0.303 |
|
| 2009 |
A-Gonzalez N, Bensinger SJ, Hong C, Beceiro S, Bradley MN, Zelcer N, Deniz J, Ramirez C, DÃaz M, Gallardo G, de Galarreta CR, Salazar J, Lopez F, Edwards P, Parks J, et al. Apoptotic cells promote their own clearance and immune tolerance through activation of the nuclear receptor LXR. Immunity. 31: 245-58. PMID 19646905 DOI: 10.1016/J.Immuni.2009.06.018 |
0.447 |
|
| 2009 |
Hsu JJ, Lu J, Huang MS, Geng Y, Sage AP, Bradley MN, Tontonoz P, Demer LL, Tintut Y. T0901317, an LXR agonist, augments PKA-induced vascular cell calcification. Febs Letters. 583: 1344-8. PMID 19327357 DOI: 10.1016/J.Febslet.2009.03.039 |
0.335 |
|
| 2009 |
Marathe C, Bradley MN, Hong C, Chao L, Wilpitz D, Salazar J, Tontonoz P. Preserved glucose tolerance in high-fat-fed C57BL/6 mice transplanted with PPARgamma-/-, PPARdelta-/-, PPARgammadelta-/-, or LXRalphabeta-/- bone marrow. Journal of Lipid Research. 50: 214-24. PMID 18772483 DOI: 10.1194/Jlr.M800189-Jlr200 |
0.426 |
|
| 2008 |
Naiki Y, Sorrentino R, Wong MH, Michelsen KS, Shimada K, Chen S, Yilmaz A, Slepenkin A, Schröder NW, Crother TR, Bulut Y, Doherty TM, Bradley M, Shaposhnik Z, Peterson EM, et al. TLR/MyD88 and liver X receptor alpha signaling pathways reciprocally control Chlamydia pneumoniae-induced acceleration of atherosclerosis. Journal of Immunology (Baltimore, Md. : 1950). 181: 7176-85. PMID 18981139 DOI: 10.4049/Jimmunol.181.10.7176 |
0.44 |
|
| 2008 |
Bensinger SJ, Bradley MN, Joseph SB, Zelcer N, Janssen EM, Hausner MA, Shih R, Parks JS, Edwards PA, Jamieson BD, Tontonoz P. LXR signaling couples sterol metabolism to proliferation in the acquired immune response. Cell. 134: 97-111. PMID 18614014 DOI: 10.1016/J.Cell.2008.04.052 |
0.383 |
|
| 2007 |
Molteni V, Li X, Nabakka J, Liang F, Wityak J, Koder A, Vargas L, Romeo R, Mitro N, Mak PA, Seidel HM, Haslam JA, Chow D, Tuntland T, Spalding TA, ... ... Bradley M, et al. N-Acylthiadiazolines, a new class of liver X receptor agonists with selectivity for LXRbeta. Journal of Medicinal Chemistry. 50: 4255-9. PMID 17665897 DOI: 10.1021/Jm070453F |
0.352 |
|
| 2007 |
Bradley MN, Hong C, Chen M, Joseph SB, Wilpitz DC, Wang X, Lusis AJ, Collins A, Hseuh WA, Collins JL, Tangirala RK, Tontonoz P. Ligand activation of LXR beta reverses atherosclerosis and cellular cholesterol overload in mice lacking LXR alpha and apoE. The Journal of Clinical Investigation. 117: 2337-46. PMID 17657314 DOI: 10.1172/Jci31909 |
0.389 |
|
| 2007 |
Ronni T, Payne KJ, Ho S, Bradley MN, Dorsam G, Dovat S. Human Ikaros function in activated T cells is regulated by coordinated expression of its largest isoforms. The Journal of Biological Chemistry. 282: 2538-47. PMID 17135265 DOI: 10.1074/Jbc.M605627200 |
0.321 |
|
| 2006 |
Marathe C, Bradley MN, Hong C, Lopez F, Ruiz de Galarreta CM, Tontonoz P, Castrillo A. The arginase II gene is an anti-inflammatory target of liver X receptor in macrophages. The Journal of Biological Chemistry. 281: 32197-206. PMID 16943198 DOI: 10.1074/Jbc.M605237200 |
0.447 |
|
| 2006 |
Chen M, Bradley MN, Beaven SW, Tontonoz P. Phosphorylation of the liver X receptors. Febs Letters. 580: 4835-41. PMID 16904112 DOI: 10.1016/J.Febslet.2006.07.074 |
0.375 |
|
| 2005 |
Bradley MN, Tontonoz P. Lesion macrophages are a key target for the antiatherogenic effects of LXR agonists. Arteriosclerosis, Thrombosis, and Vascular Biology. 25: 10-1. PMID 15626767 DOI: 10.1161/01.Atv.0000152727.69018.61 |
0.458 |
|
| 2005 |
Bradley MN, Tontonoz P. LXR: A nuclear receptor target for cardiovascular disease? Drug Discovery Today: Therapeutic Strategies. 2: 97-103. DOI: 10.1016/J.Ddstr.2005.05.018 |
0.317 |
|
| 2004 |
Joseph SB, Bradley MN, Castrillo A, Bruhn KW, Mak PA, Pei L, Hogenesch J, O'connell RM, Cheng G, Saez E, Miller JF, Tontonoz P. LXR-dependent gene expression is important for macrophage survival and the innate immune response. Cell. 119: 299-309. PMID 15479645 DOI: 10.1016/J.Cell.2004.09.032 |
0.479 |
|
| 2003 |
Bradley MN, Zhou L, Smale ST. C/EBPbeta regulation in lipopolysaccharide-stimulated macrophages. Molecular and Cellular Biology. 23: 4841-58. PMID 12832471 DOI: 10.1128/Mcb.23.14.4841-4858.2003 |
0.587 |
|
| 2001 |
Weinmann AS, Mitchell DM, Sanjabi S, Bradley MN, Hoffmann A, Liou HC, Smale ST. Nucleosome remodeling at the IL-12 p40 promoter is a TLR-dependent, Rel-independent event. Nature Immunology. 2: 51-7. PMID 11135578 DOI: 10.1038/83168 |
0.57 |
|
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