Brian N. Giunta, Ph.D. - Publications

Affiliations: 
2011 Medical Sciences University of South Florida, Tampa, FL, United States 
Area:
Alzheimer's Disease, Down Syndrome

59 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Sawmiller D, Habib A, Hou H, Mori T, Fan A, Tian J, Zeng J, Giunta B, Sanberg PR, Mattson MP, Tan J. A Novel Apolipoprotein E Antagonist Functionally Blocks Apolipoprotein E Interaction With N-terminal Amyloid Precursor Protein, Reduces β-Amyloid-Associated Pathology, and Improves Cognition. Biological Psychiatry. PMID 31208706 DOI: 10.1016/J.Biopsych.2019.04.026  0.4
2018 Habib A, Hou H, Mori T, Tian J, Zeng J, Fan S, Giunta B, Sanberg PR, Sawmiller D, Tan J. Human Umbilical Cord Blood Serum-derived α-Secretase: Functional Testing in Alzheimer's Disease Mouse Models. Cell Transplantation. 963689718759473. PMID 29560732 DOI: 10.1177/0963689718759473  0.4
2018 Leon M, Sawmiller D, Giunta B, Tan J. Therapeutic approach targeting apolipoprotein E binding region and low-density lipoprotein receptor for Alzheimer’s disease Neuroimmunology and Neuroinflammation. 5: 30. DOI: 10.20517/2347-8659.2018.26  0.4
2017 Habib A, Sawmiller D, Li S, Xiang Y, Rongo D, Tian J, Hou H, Zeng J, Smith A, Fan S, Giunta B, Mori T, Currier G, Shytle DR, Tan J. LISPRO mitigates β-amyloid and associated pathologies in Alzheimer's mice. Cell Death & Disease. 8: e2880. PMID 28617434 DOI: 10.1038/Cddis.2017.279  0.4
2017 Hou H, Habib A, Zi D, Tian K, Tian J, Giunta B, Sawmiller D, Tan J. Low-Density Lipoprotein Receptor-Related Protein-1 (LRP1) C4408R Mutant Promotes Amyloid Precursor Protein (APP) α-Cleavage in Vitro. Neuromolecular Medicine. PMID 28612181 DOI: 10.1007/S12017-017-8446-X  0.4
2016 Jin J, Grimmig B, Izzo J, Brown LAM, Hudson C, Smith AJ, Tan J, Bickford PC, Giunta B. HIV Non-Nucleoside Reverse Transcriptase Inhibitor Efavirenz Reduces Neural Stem Cell Proliferation in Vitro and in Vivo. Cell Transplantation. 25: 1967-1977. PMID 28836850 DOI: 10.3727/096368916X691457  0.4
2016 Sawmiller D, Habib A, Li S, Darlington D, Hou H, Tian J, Shytle RD, Smith A, Giunta B, Mori T, Tan J. Diosmin reduces cerebral Aβ levels, tau hyperphosphorylation, neuroinflammation, and cognitive impairment in the 3xTg-AD mice. Journal of Neuroimmunology. 299: 98-106. PMID 27725131 DOI: 10.1016/J.Jneuroim.2016.08.018  0.4
2015 Xiang Y, Bu XL, Liu YH, Zhu C, Shen LL, Jiao SS, Zhu XY, Giunta B, Tan J, Song WH, Zhou HD, Zhou XF, Wang YJ. Physiological amyloid-beta clearance in the periphery and its therapeutic potential for Alzheimer's disease. Acta Neuropathologica. 130: 487-99. PMID 26363791 DOI: 10.1007/S00401-015-1477-1  0.4
2015 Deng J, Habib A, Obregon DF, Barger SW, Giunta B, Wang YJ, Hou H, Sawmiller D, Tan J. Soluble amyloid precursor protein alpha (sAPPα) inhibits tau phosphorylation through modulation of GSK3β signaling pathway. Journal of Neurochemistry. PMID 26342176 DOI: 10.1111/Jnc.13351  0.4
2015 Darlington D, Li S, Hou H, Habib A, Tian J, Gao Y, Ehrhart J, Sanberg PR, Sawmiller D, Giunta B, Mori T, Tan J. Human umbilical cord blood-derived monocytes improve cognitive deficits and reduce β-amyloid pathology in PSAPP mice. Cell Transplantation. PMID 26230612 DOI: 10.3727/096368915X688894  0.4
2015 Li S, Hou H, Mori T, Sawmiller D, Smith A, Tian J, Wang Y, Giunta B, Sanberg PR, Zhang S, Tan J. Swedish mutant APP-based BACE1 binding site peptide reduces APP β-cleavage and cerebral Aβ levels in Alzheimer's mice. Scientific Reports. 5: 11322. PMID 26091071 DOI: 10.1038/Srep11322  0.4
2015 Liu YH, Wang YR, Xiang Y, Zhou HD, Giunta B, Mañucat-Tan NB, Tan J, Zhou XF, Wang YJ. Clearance of amyloid-beta in Alzheimer's disease: shifting the action site from center to periphery. Molecular Neurobiology. 51: 1-7. PMID 24733588 DOI: 10.1007/S12035-014-8694-9  0.4
2014 Brown LA, Scarola J, Smith AJ, Sanberg PR, Tan J, Giunta B. The role of tau protein in HIV-associated neurocognitive disorders. Molecular Neurodegeneration. 9: 40. PMID 25304757 DOI: 10.1186/1750-1326-9-40  0.4
2014 Ferrell D, Giunta B. The impact of HIV-1 on neurogenesis: implications for HAND. Cellular and Molecular Life Sciences : Cmls. 71: 4387-92. PMID 25134912 DOI: 10.1007/S00018-014-1702-4  0.4
2014 Liu YH, Xiang Y, Wang YR, Jiao SS, Wang QH, Bu XL, Zhu C, Yao XQ, Giunta B, Tan J, Zhou HD, Wang YJ. Association Between Serum Amyloid-Beta and Renal Functions: Implications for Roles of Kidney in Amyloid-Beta Clearance. Molecular Neurobiology. PMID 25119777 DOI: 10.1007/S12035-014-8854-Y  0.4
2014 Li S, Deng J, Hou H, Tian J, Giunta B, Wang Y, Sawmiller D, Smith A, Sanberg PR, Obregon D, Mori T, Tan J. Specific antibody binding to the APP672-699 region shifts APP processing from α- to β-cleavage. Cell Death & Disease. 5: e1374. PMID 25118934 DOI: 10.1038/Cddis.2014.336  0.4
2014 Brown LA, Jin J, Ferrell D, Sadic E, Obregon D, Smith AJ, Tan J, Giunta B. Efavirenz promotes β-secretase expression and increased Aβ1-40,42 via oxidative stress and reduced microglial phagocytosis: implications for HIV associated neurocognitive disorders (HAND). Plos One. 9: e95500. PMID 24759994 DOI: 10.1371/Journal.Pone.0095500  0.4
2014 Sawmiller D, Li S, Shahaduzzaman M, Smith AJ, Obregon D, Giunta B, Borlongan CV, Sanberg PR, Tan J. Luteolin reduces Alzheimer's disease pathologies induced by traumatic brain injury. International Journal of Molecular Sciences. 15: 895-904. PMID 24413756 DOI: 10.3390/Ijms15010895  0.4
2013 Smith AJ, Kim SH, Duggirala NK, Jin J, Wojtas L, Ehrhart J, Giunta B, Tan J, Zaworotko MJ, Shytle RD. Improving lithium therapeutics by crystal engineering of novel ionic cocrystals. Molecular Pharmaceutics. 10: 4728-38. PMID 24191685 DOI: 10.1021/Mp400571A  0.4
2013 Zhang SQ, Sawmiller D, Li S, Rezai-Zadeh K, Hou H, Zhou S, Shytle D, Giunta B, Fernandez F, Mori T, Tan J. Octyl gallate markedly promotes anti-amyloidogenic processing of APP through estrogen receptor-mediated ADAM10 activation. Plos One. 8: e71913. PMID 23977176 DOI: 10.1371/Journal.Pone.0071913  0.4
2013 Liu YH, Zeng F, Wang YR, Zhou HD, Giunta B, Tan J, Wang YJ. Immunity and Alzheimer's disease: immunological perspectives on the development of novel therapies. Drug Discovery Today. 18: 1212-20. PMID 23954180 DOI: 10.1016/J.Drudis.2013.07.020  0.4
2013 Zhang SQ, Obregon D, Ehrhart J, Deng J, Tian J, Hou H, Giunta B, Sawmiller D, Tan J. Baicalein reduces β-amyloid and promotes nonamyloidogenic amyloid precursor protein processing in an Alzheimer's disease transgenic mouse model. Journal of Neuroscience Research. 91: 1239-46. PMID 23686791 DOI: 10.1002/Jnr.23244  0.4
2013 Hernandez-Ontiveros DG, Tajiri N, Acosta S, Giunta B, Tan J, Borlongan CV. Microglia activation as a biomarker for traumatic brain injury. Frontiers in Neurology. 4: 30. PMID 23531681 DOI: 10.3389/Fneur.2013.00030  0.4
2013 Darlington D, Deng J, Giunta B, Hou H, Sanberg CD, Kuzmin-Nichols N, Zhou HD, Mori T, Ehrhart J, Sanberg PR, Tan J. Multiple low-dose infusions of human umbilical cord blood cells improve cognitive impairments and reduce amyloid-β-associated neuropathology in Alzheimer mice. Stem Cells and Development. 22: 412-21. PMID 22816379 DOI: 10.1089/Scd.2012.0345  0.4
2013 Obregon D, Fernandez F, Tan J, Giunta B, Haley JA. The Impact of HAART on Advanced Brain Aging: Implications for Mitochondrial Dysfunction and APP Processing Journal of Antivirals & Antiretrovirals. 5: 1-6. DOI: 10.4172/Jaa.S10-003  0.4
2013 Giunta B, Hervey W, Klippel C, Obregon D, Robben D, Hartney K, Ciccone BLd, Fernandez F. Psychiatric Complications of HIV Infection: An Overview Psychiatric Annals. 43: 199-203. DOI: 10.3928/00485713-20130503-03  0.4
2013 Giunta B, Tan J. Chapter 118 – Green Tea (−)-Epigallocatechin-3-Gallate and Amyloid Precursor Protein: Implications for Alzheimer's Disease Tea in Health and Disease Prevention. 1411-1423. DOI: 10.1016/B978-0-12-384937-3.00118-X  0.4
2012 Giunta B, Deng J, Jin J, Sadic E, Rum S, Zhou H, Sanberg P, Tan J. EVALUATION OF HOW CIGARETTE SMOKE IS A DIRECT RISK FACTOR FOR ALZHEIMER'S DISEASE. Technology and Innovation. 14: 39-48. PMID 22997546 DOI: 10.3727/194982412X13378627621752  0.4
2012 Giunta B, Obregon D, Velisetty R, Sanberg PR, Borlongan CV, Tan J. The immunology of traumatic brain injury: a prime target for Alzheimer's disease prevention. Journal of Neuroinflammation. 9: 185. PMID 22849382 DOI: 10.1186/1742-2094-9-185  0.4
2012 Liu Y, Giunta B, Zhou H, Tan J, Wang Y. Immunotherapy for Alzheimer disease—the challenge of adverse effects Nature Reviews Neurology. 8: 465-469. PMID 22751529 DOI: 10.1038/Nrneurol.2012.118  0.4
2012 Obregon D, Hou H, Deng J, Giunta B, Tian J, Darlington D, Shahaduzzaman M, Zhu Y, Mori T, Mattson MP, Tan J. Soluble amyloid precursor protein-α modulates β-secretase activity and amyloid-β generation. Nature Communications. 3: 777. PMID 22491325 DOI: 10.1038/Ncomms1781  0.4
2012 Deng J, Hou H, Giunta B, Mori T, Wang YJ, Fernandez F, Weggen S, Araki W, Obregon D, Tan J. Autoreactive-Aβ antibodies promote APP β-secretase processing. Journal of Neurochemistry. 120: 732-40. PMID 22188568 DOI: 10.1111/J.1471-4159.2011.07629.X  0.4
2011 Giunta B, Ehrhart J, Obregon DF, Lam L, Le L, Jin J, Fernandez F, Tan J, Shytle RD. Antiretroviral medications disrupt microglial phagocytosis of β-amyloid and increase its production by neurons: implications for HIV-associated neurocognitive disorders. Molecular Brain. 4: 23. PMID 21649911 DOI: 10.1186/1756-6606-4-23  0.4
2011 Zhu Y, Hou H, Rezai-Zadeh K, Giunta B, Ruscin A, Gemma C, Jin J, Dragicevic N, Bradshaw P, Rasool S, Glabe CG, Ehrhart J, Bickford P, Mori T, Obregon D, et al. CD45 deficiency drives amyloid-β peptide oligomers and neuronal loss in Alzheimer's disease mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 31: 1355-65. PMID 21273420 DOI: 10.1523/Jneurosci.3268-10.2011  0.4
2011 Salemi J, Obregon DF, Cobb A, Reed S, Sadic E, Jin J, Fernandez F, Tan J, Giunta B. Flipping the switches: CD40 and CD45 modulation of microglial activation states in HIV associated dementia (HAD). Molecular Neurodegeneration. 6: 3. PMID 21223591 DOI: 10.1186/1750-1326-6-3  0.4
2011 Zhu Y, Obregon D, Hou H, Giunta B, Ehrhart J, Fernandez F, Mori T, Nikolic W, Zhao Y, Morgan D, Town T, Tan J. Mutant presenilin-1 deregulated peripheral immunity exacerbates Alzheimer-like pathology. Journal of Cellular and Molecular Medicine. 15: 327-38. PMID 19900216 DOI: 10.1111/J.1582-4934.2009.00962.X  0.4
2011 Hou H, Obregon D, Shahaduzzaman MD, Song M, Tian J, Giunta B, Mori T, Mattson M, Tan J. sAPP-alpha modulates gamma-secretase processing of APP Alzheimers & Dementia. 7. DOI: 10.1016/J.Jalz.2011.05.1165  0.4
2010 Zhang S, Salemi J, Hou H, Zhu Y, Mori T, Giunta B, Obregon D, Tan J. Rapamycin promotes β-amyloid production via ADAM-10 inhibition Biochemical and Biophysical Research Communications. 398: 337-341. PMID 20542014 DOI: 10.1016/J.Bbrc.2010.06.017  0.4
2010 Giunta B, Rezai-Zadeh K, Tan J. Impact of the CD40-CD40L dyad in Alzheimer's disease. Cns & Neurological Disorders Drug Targets. 9: 149-55. PMID 20205645 DOI: 10.2174/187152710791012099  0.4
2010 Giunta B, Hou H, Zhu Y, Salemi J, Ruscin A, Shytle RD, Tan J. Fish oil enhances anti-amyloidogenic properties of green tea EGCG in Tg2576 mice. Neuroscience Letters. 471: 134-138. PMID 20096749 DOI: 10.1016/J.Neulet.2010.01.026  0.4
2010 Smith A, Giunta B, Bickford PC, Fountain M, Tan J, Shytle RD. Nanolipidic particles improve the bioavailability and alpha-secretase inducing ability of epigallocatechin-3-gallate (EGCG) for the treatment of Alzheimer's disease. International Journal of Pharmaceutics. 389: 207-12. PMID 20083179 DOI: 10.1016/J.Ijpharm.2010.01.012  0.4
2010 Giunta B, Ruscin A, Salemi J, Wolfson A, Fernandez F, Tan J. The central role of T-cell memory in Alzheimer’s disease vaccination Ageing Research. 1: 5. DOI: 10.4081/Ar.2010.E5  0.4
2010 Tan J, Zhu Y, Hou H, Jin J, Mori T, Gemma C, Obregon D, Dragicevic N, Bradshaw P, Bickford P, Town T, Giunta B. CD45 deficency promotes neurodegeneration in PSAPP mice Alzheimers & Dementia. 6. DOI: 10.1016/J.Jalz.2010.05.423  0.4
2009 Giunta B, Figueroa KP, Town T, Tan J. SOLUBLE CD40 LIGAND IN DEMENTIA. Drugs of the Future. 34: 333-340. PMID 19777117 DOI: 10.1358/Dof.2009.034.04.1358595  0.4
2009 Parker-Athill E, Luo D, Bailey A, Giunta B, Tian J, Shytle RD, Murphy T, Legradi G, Tan J. Flavonoids, a prenatal prophylaxis via targeting JAK2/STAT3 signaling to oppose IL-6/MIA associated autism Journal of Neuroimmunology. 217: 20-27. PMID 19766327 DOI: 10.1016/J.Jneuroim.2009.08.012  0.4
2009 Caserta MT, Bannon Y, Fernandez F, Giunta B, Schoenberg MR, Tan J. Normal brain aging clinical, immunological, neuropsychological, and neuroimaging features. International Review of Neurobiology. 84: 1-19. PMID 19501710 DOI: 10.1016/S0074-7742(09)00401-2  0.4
2009 Shapshak P, Somboonwit C, Drumright LN, Frost SDW, Commins D, Tellinghuisen TL, Scott WK, Duncan R, McCoy C, Page JB, Giunta B, Fernandez F, Singer E, Levine A, Minagar A, et al. Molecular and Contextual Markers of Hepatitis C Virus and Drug Abuse Molecular Diagnosis & Therapy. 13: 153-179. DOI: 10.1007/Bf03256323  0.4
2008 Bailey AR, Giunta BN, Obregon D, Nikolic WV, Tian J, Sanberg CD, Sutton DT, Tan J. Peripheral biomarkers in Autism: secreted amyloid precursor protein-alpha as a probable key player in early diagnosis. International Journal of Clinical and Experimental Medicine. 1: 338-44. PMID 19079679  0.4
2008 Giunta B, Fernandez F, Nikolic WV, Obregon D, Rrapo E, Town T, Tan J. Inflammaging as a prodrome to Alzheimer's disease. Journal of Neuroinflammation. 5: 51. PMID 19014446 DOI: 10.1186/1742-2094-5-51  0.4
2008 Zhu Y, Bickford PC, Sanberg P, Giunta B, Tan J. Blueberry opposes beta-amyloid peptide-induced microglial activation via inhibition of p44/42 mitogen-activation protein kinase. Rejuvenation Research. 11: 891-901. PMID 18789000 DOI: 10.1089/Rej.2008.0757  0.4
2008 Zhu Y, Hou H, Nikolic WV, Ehrhart J, Rrapo E, Bickford P, Giunta B, Tan J. CD45RB is a novel molecular therapeutic target to inhibit Abeta peptide-induced microglial MAPK activation. Plos One. 3: e2135. PMID 18478117 DOI: 10.1371/Journal.Pone.0002135  0.4
2008 Nikolic WV, Hou H, Town T, Zhu Y, Giunta B, Sanberg CD, Zeng J, Luo D, Ehrhart J, Mori T, Sanberg PR, Tan J. Peripherally administered human umbilical cord blood cells reduce parenchymal and vascular beta-amyloid deposits in Alzheimer mice. Stem Cells and Development. 17: 423-39. PMID 18366296 DOI: 10.1089/Scd.2008.0018  0.4
2008 Obregon D, Hou H, Bai Y, Nikolic WV, Mori T, Luo D, Zeng J, Ehrhart J, Fernandez F, Morgan D, Giunta B, Town T, Tan J. CD40L disruption enhances Abeta vaccine-mediated reduction of cerebral amyloidosis while minimizing cerebral amyloid angiopathy and inflammation. Neurobiology of Disease. 29: 336-53. PMID 18055209 DOI: 10.1016/J.Nbd.2007.09.009  0.4
2007 Giunta B, Somboonwit C, Nikolic WV, Rrapo E, Tan J, Shapshak P, Fernandez F. Psychiatric implications of hepatitis-C infection. Critical Reviews in Neurobiology. 19: 79-118. PMID 19409058 DOI: 10.1615/Critrevneurobiol.V19.I2-3.20  0.4
2007 Legradi G, Das M, Giunta B, Hirani K, Mitchell EA, Diamond DM. Microinfusion of pituitary adenylate cyclase-activating polypeptide into the central nucleus of amygdala of the rat produces a shift from an active to passive mode of coping in the shock-probe fear/defensive burying test. Neural Plasticity. 2007: 79102. PMID 17641738 DOI: 10.1155/2007/79102  0.4
2007 Nikolic WV, Bai Y, Obregon D, Hou H, Mori T, Zeng J, Ehrhart J, Shytle RD, Giunta B, Morgan D, Town T, Tan J. Transcutaneous beta-amyloid immunization reduces cerebral beta-amyloid deposits without T cell infiltration and microhemorrhage. Proceedings of the National Academy of Sciences of the United States of America. 104: 2507-12. PMID 17264212 DOI: 10.1073/Pnas.0609377104  0.4
2006 Giunta B, Obregon D, Hou H, Zeng J, Sun N, Nikolic V, Ehrhart J, Shytle D, Fernandez F, Tan J. EGCG mitigates neurotoxicity mediated by HIV-1 proteins gp120 and Tat in the presence of IFN-gamma: role of JAK/STAT1 signaling and implications for HIV-associated dementia. Brain Research. 1123: 216-25. PMID 17078933 DOI: 10.1016/J.Brainres.2006.09.057  0.4
2004 Giunta B, Ehrhart J, Townsend K, Sun N, Vendrame M, Shytle D, Tan J, Fernandez F. Galantamine and nicotine have a synergistic effect on inhibition of microglial activation induced by HIV-1 gp120 Brain Research Bulletin. 64: 165-170. PMID 15342104 DOI: 10.1016/J.Brainresbull.2004.06.008  0.4
2002 Tranberg CE, Zickgraf A, Giunta BN, Luetjens H, Figler H, Murphree LJ, Falke R, Fleischer H, Linden J, Scammells PJ, Olsson RA. 2-Amino-3-aroyl-4,5-alkylthiophenes: agonist allosteric enhancers at human A(1) adenosine receptors. Journal of Medicinal Chemistry. 45: 382-9. PMID 11784142 DOI: 10.1021/jm010081p  0.4
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