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Kirk J. Wangensteen, Ph.D. - Publications

Affiliations: 
2007 University of Minnesota, Twin Cities, Minneapolis, MN 
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35 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Adlat S, Vázquez Salgado AM, Lee M, Yin D, Wangensteen KJ. Emerging and potential use of CRISPR in human liver disease. Hepatology (Baltimore, Md.). PMID 37607734 DOI: 10.1097/HEP.0000000000000578  0.388
2020 Mezina AI, Philips N, Bogus Z, Erez N, Nathanson KL, Hoteit M, Wangensteen KJ. Mo1404 PREVALENCE OF PATHOGENIC GERMLINE VARIANTS IN CANCER-RISK GENES IN HEPATOCELLULAR CARCINOMA Gastroenterology. 158: S-1396. DOI: 10.1016/S0016-5085(20)34158-5  0.323
2019 Zahm AM, Wang AW, Wang YJ, Schug J, Wangensteen KJ, Kaestner KH. High-content Screen Identifies MicroRNAs Required for Liver Repopulation After Injury in Mice. Gastroenterology. PMID 31759059 DOI: 10.1053/J.Gastro.2019.11.025  0.318
2019 Wang AW, Wang YJ, Zahm AM, Morgan AR, Wangensteen KJ, Kaestner KH. The dynamic chromatin architecture of the regenerating liver. Cellular and Molecular Gastroenterology and Hepatology. PMID 31629814 DOI: 10.1016/J.Jcmgh.2019.09.006  0.369
2019 Wang AW, Zahm AM, Wangensteen KJ. Cell Type-specific Gene Expression Profiling in the Mouse Liver. Journal of Visualized Experiments : Jove. PMID 31609340 DOI: 10.3791/60242  0.462
2019 Kieckhaefer JE, Maina F, Wells RG, Wangensteen KJ. Liver Cancer Gene Discovery Using Gene Targeting, Sleeping Beauty, and CRISPR/Cas9. Seminars in Liver Disease. PMID 30912094 DOI: 10.1055/S-0039-1678725  0.43
2019 Wang L, Nathanson JT, Long J, Ebrahimzadeh J, Kumar S, Wangensteen KJ, Katona BW, Rustgi AK. Tu1673 – Single-Gene Vs. Multi-Gene Panel Testing in Management of Hereditary Gastrointestinal Cancer Syndromes Gastroenterology. 156: S-1086. DOI: 10.1016/S0016-5085(19)39677-5  0.346
2018 Wang C, Chen WJ, Wu YF, You P, Zheng SY, Liu CC, Xiang D, Wang MJ, Cai YC, Zhao QH, Borjigin U, Liu W, Xiong WJ, Wangensteen KJ, Wang X, et al. The extent of liver injury determines hepatocyte fate toward senescence or cancer. Cell Death & Disease. 9: 575. PMID 29760381 DOI: 10.1038/S41419-018-0622-X  0.337
2018 Wang AW, Wangensteen KJ, Wang YJ, Zahm AM, Moss NG, Erez N, Kaestner KH. TRAP-seq identifies cystine/glutamate antiporter as a driver of recovery from liver injury. The Journal of Clinical Investigation. PMID 29517978 DOI: 10.1172/Jci95120  0.455
2018 Wang MJ, Chen F, Liu QG, Liu CC, Yao H, Yu B, Zhang HB, Yan HX, Ye Y, Chen T, Wangensteen KJ, Wang X, Hu YP, He ZY. Insulin-like growth factor 2 is a key mitogen driving liver repopulation in mice. Cell Death & Disease. 9: 26. PMID 29348399 DOI: 10.1038/S41419-017-0186-1  0.398
2017 Wangensteen KJ, Wang YJ, Dou Z, Wang AW, Mosleh-Shirazi E, Horlbeck MA, Gilbert LA, Weissman JS, Berger SL, Kaestner KH. Combinatorial genetics in liver repopulation and carcinogenesis with a novel in vivo CRISPR activation platform. Hepatology (Baltimore, Md.). PMID 29091290 DOI: 10.1002/Hep.29626  0.508
2017 Dou Z, Ghosh K, Vizioli MG, Zhu J, Sen P, Wangensteen KJ, Simithy J, Lan Y, Lin Y, Zhou Z, Capell BC, Xu C, Xu M, Kieckhaefer JE, Jiang T, et al. Cytoplasmic chromatin triggers inflammation in senescence and cancer. Nature. PMID 28976970 DOI: 10.1038/Nature24050  0.364
2016 De Luca-Johnson J, Wangensteen KJ, Hanson J, Krawitt E, Wilcox R. Natural History of Patients Presenting with Autoimmune Hepatitis and Coincident Nonalcoholic Fatty Liver Disease. Digestive Diseases and Sciences. PMID 27262844 DOI: 10.1007/S10620-016-4213-3  0.334
2016 Shin S, Wangensteen KJ, Teta-Bissett M, Wang YJ, Mosleh-Shirazi E, Buza EL, Greenbaum LE, Kaestner KH. Genetic Lineage Tracing Analysis of the Cell of Origin of Hepatotoxin-Induced Liver Tumors in Mice. Hepatology (Baltimore, Md.). PMID 27099001 DOI: 10.1002/Hep.28602  0.377
2016 Ni J, Wangensteen KJ, Nelsen D, Balciunas D, Skuster KJ, Urban MD, Ekker SC. Active recombinant Tol2 transposase for gene transfer and gene discovery applications. Mobile Dna. 7: 6. PMID 27042235 DOI: 10.1186/S13100-016-0062-Z  0.575
2015 Wangensteen KJ, Zhang S, Greenbaum LE, Kaestner KH. A genetic screen reveals Foxa3 and TNFR1 as key regulators of liver repopulation. Genes & Development. 29: 904-9. PMID 25934503 DOI: 10.1101/Gad.258855.115  0.457
2014 Xiang D, Liu CC, Wang MJ, Li JX, Chen F, Yao H, Yu B, Lu L, Borjigin U, Chen YX, Zhong L, Wangensteen KJ, He ZY, Wang X, Hu YP. Non-viral FoxM1 gene delivery to hepatocytes enhances liver repopulation. Cell Death & Disease. 5: e1252. PMID 24853430 DOI: 10.1038/cddis.2014.230  0.354
2014 Wang MJ, Chen F, Li JX, Liu CC, Zhang HB, Xia Y, Yu B, You P, Xiang D, Lu L, Yao H, Borjigin U, Yang GS, Wangensteen KJ, He ZY, et al. Reversal of hepatocyte senescence after continuous in vivo cell proliferation. Hepatology (Baltimore, Md.). 60: 349-61. PMID 24711261 DOI: 10.1002/Hep.27094  0.384
2014 Wangensteen KJ, Greenbaum L, Kaestner KH. 644 A Genetic Screen to Identify and Rank Regulators of Liver Repopulation Following Toxic Injury Gastroenterology. 146: S-919. DOI: 10.1016/S0016-5085(14)63340-0  0.363
2013 Yu B, He ZY, You P, Han QW, Xiang D, Chen F, Wang MJ, Liu CC, Lin XW, Borjigin U, Zi XY, Li JX, Zhu HY, Li WL, Han CS, ... Wangensteen KJ, et al. Reprogramming fibroblasts into bipotential hepatic stem cells by defined factors. Cell Stem Cell. 13: 328-40. PMID 23871605 DOI: 10.1016/J.Stem.2013.06.017  0.398
2012 He ZY, Deng L, Li YF, Xiang D, Hu JK, Chen YX, Wang MJ, Chen F, Liu CC, Li WL, Zi XY, Wu X, Li GP, Wangensteen KJ, Hu YP, et al. Murine embryonic stem cell-derived hepatocytes correct metabolic liver disease after serial liver repopulation. The International Journal of Biochemistry & Cell Biology. 44: 648-58. PMID 22249028 DOI: 10.1016/J.Biocel.2012.01.002  0.406
2011 Li F, He Z, Li Y, Liu P, Chen F, Wang M, Zhu H, Ding X, Wangensteen KJ, Hu Y, Wang X. Combined activin A/LiCl/Noggin treatment improves production of mouse embryonic stem cell-derived definitive endoderm cells. Journal of Cellular Biochemistry. 112: 1022-34. PMID 21400570 DOI: 10.1002/Jcb.22962  0.304
2010 Li F, Liu P, Liu C, Xiang D, Deng L, Li W, Wangensteen K, Song J, Ma Y, Hui L, Wei L, Li L, Ding X, Hu Y, He Z, et al. Hepatoblast-like progenitor cells derived from embryonic stem cells can repopulate livers of mice. Gastroenterology. 139: 2158-2169.e8. PMID 20801124 DOI: 10.1053/J.Gastro.2010.08.042  0.397
2010 He Z, Zhang H, Zhang X, Xie D, Chen Y, Wangensteen KJ, Ekker SC, Firpo M, Liu C, Xiang D, Zi X, Hui L, Yang G, Ding X, Hu Y, et al. Liver xeno-repopulation with human hepatocytes in Fah-/-Rag2-/- mice after pharmacological immunosuppression. The American Journal of Pathology. 177: 1311-9. PMID 20651238 DOI: 10.2353/Ajpath.2010.091154  0.58
2009 Keng VW, Ryan BJ, Wangensteen KJ, Balciunas D, Schmedt C, Ekker SC, Largaespada DA. Efficient transposition of Tol2 in the mouse germline. Genetics. 183: 1565-73. PMID 19805821 DOI: 10.1534/Genetics.109.100768  0.567
2008 Wangensteen KJ, Wilber A, Keng VW, He Z, Matise I, Wangensteen L, Carson CM, Chen Y, Steer CJ, McIvor RS, Largaespada DA, Wang X, Ekker SC. A facile method for somatic, lifelong manipulation of multiple genes in the mouse liver. Hepatology (Baltimore, Md.). 47: 1714-24. PMID 18435462 DOI: 10.1002/Hep.22195  0.663
2008 Wangensteen KJ, Wilber A, Keng VW, Chen Y, Matise I, Wangensteen L, Steer CJ, McIvor RS, Largaespada DA, Wang X, Ekker SC. A method for lifelong genetic manipulation of regenerating hepatocytes in mouse Cell Research. 18: S31-S31. DOI: 10.1038/Cr.2008.121  0.54
2007 Wilber A, Wangensteen KJ, Chen Y, Zhuo L, Frandsen JL, Bell JB, Chen ZJ, Ekker SC, McIvor RS, Wang X. Messenger RNA as a source of transposase for sleeping beauty transposon-mediated correction of hereditary tyrosinemia type I. Molecular Therapy : the Journal of the American Society of Gene Therapy. 15: 1280-7. PMID 17440442 DOI: 10.1038/Sj.Mt.6300160  0.614
2006 Balciunas D, Wangensteen KJ, Wilber A, Bell J, Geurts A, Sivasubbu S, Wang X, Hackett PB, Largaespada DA, McIvor RS, Ekker SC. Harnessing a high cargo-capacity transposon for genetic applications in vertebrates. Plos Genetics. 2: e169. PMID 17096595 DOI: 10.1371/Journal.Pgen.0020169  0.61
2006 Sivasubbu S, Balciunas D, Davidson AE, Pickart MA, Hermanson SB, Wangensteen KJ, Wolbrink DC, Ekker SC. Gene-breaking transposon mutagenesis reveals an essential role for histone H2afza in zebrafish larval development. Mechanisms of Development. 123: 513-29. PMID 16859902 DOI: 10.1016/J.Mod.2006.06.002  0.688
2006 Wilber A, Wangensteen KJ, Chen Y, Zhou L, Frandsen JL, Bell J, Chen Z, Ekker SC, McIvor RS, Wang X. 405. Correction of the Murine Model of Hereditary Tyrosinemia Type I Using Messenger RNA as a Source of Transposase for Sleeping Beauty Mediated Integration of the FAH Gene Molecular Therapy. 13: S155-S156. DOI: 10.1016/J.Ymthe.2006.08.468  0.648
2006 Balciunas D, Wilber A, Wangensteen K, Bell J, Geurts A, Hackett PB, Largaespada DA, McIvor RS, Ekker SC. 385. Tol2 Transposon as a Gene Therapy Vector: Characterization, Optimization and Correction of Hereditary Tyrosinemia Type 1 in Mouse Molecular Therapy. 13: S147. DOI: 10.1016/J.Ymthe.2006.08.446  0.609
2005 Wilber A, Frandsen JL, Wangensteen KJ, Ekker SC, Wang X, McIvor RS. Dynamic gene expression after systemic delivery of plasmid DNA as determined by in vivo bioluminescence imaging. Human Gene Therapy. 16: 1325-32. PMID 16259566 DOI: 10.1089/Hum.2005.16.1325  0.634
2005 Wangensteen KJ, Wilber A, Zeng G, Frandsen JL, McIvor RS, Ekker SC, Wang X. 1068. Luciferase as an In Vivo Reporter for Selective Liver Repopulation in Adult FAH-/- Mice Molecular Therapy. 11. DOI: 10.1016/J.Ymthe.2005.07.615  0.644
2004 Wangensteen KJ, Chen ZJ, Steer CJ, Ekker SC. 154. Small inhibitory RNA expressed from sleeping beauty transposons can reduce alpha1-antitrypsin expression Molecular Therapy. 9. DOI: 10.1016/J.Ymthe.2004.06.077  0.62
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