| Year |
Citation |
Score |
| 2022 |
Ghanam RH, Eastep GN, Saad JS. Structural Insights into the Mechanism of HIV-1 Tat Secretion from the Plasma Membrane. Journal of Molecular Biology. 435: 167880. PMID 36370804 DOI: 10.1016/j.jmb.2022.167880 |
0.344 |
|
| 2022 |
Herrmann D, Hanson HM, Zhou LW, Addabbo R, Willkomm NA, Angert I, Mueller JD, Mansky LM, Saad JS. Molecular Determinants of Human T-cell Leukemia Virus Type 1 Gag Targeting to the Plasma Membrane for Assembly. Journal of Molecular Biology. 167609. PMID 35490898 DOI: 10.1016/j.jmb.2022.167609 |
0.306 |
|
| 2021 |
Herrmann D, Zhou LW, Hanson HM, Willkomm NA, Mansky LM, Saad JS. Structural Insights into the Mechanism of Human T-cell Leukemia Virus Type 1 Gag Targeting to the Plasma Membrane for Assembly. Journal of Molecular Biology. 433: 167161. PMID 34298060 DOI: 10.1016/j.jmb.2021.167161 |
0.347 |
|
| 2021 |
Eastep GN, Ghanam RH, Green TJ, Saad JS. Structural characterization of HIV-1 matrix mutants implicated in envelope incorporation. The Journal of Biological Chemistry. 100321. PMID 33485964 DOI: 10.1016/j.jbc.2021.100321 |
0.314 |
|
| 2020 |
Murphy RE, Saad JS. The Interplay between HIV-1 Gag Binding to the Plasma Membrane and Env Incorporation. Viruses. 12. PMID 32429351 DOI: 10.3390/V12050548 |
0.411 |
|
| 2019 |
Murphy RE, Samal AB, Vlach J, Mas V, Prevelige PE, Saad JS. Structural and biophysical characterizations of HIV-1 matrix trimer binding to lipid nanodiscs shed light on virus assembly. The Journal of Biological Chemistry. PMID 31640987 DOI: 10.1074/Jbc.Ra119.010997 |
0.461 |
|
| 2018 |
Tak U, Vlach J, Garza-Garcia A, William D, Danilchanka O, de Carvalho LPS, Saad JS, Niederweis M. The tuberculosis necrotizing toxin is an NAD and NADP glycohydrolase with distinct enzymatic properties. The Journal of Biological Chemistry. PMID 30593509 DOI: 10.1074/Jbc.Ra118.005832 |
0.312 |
|
| 2018 |
Vlach J, Eastep GN, Ghanam RH, Watanabe SM, Carter C, Saad JS. Structural basis for targeting avian sarcoma virus Gag polyprotein to the plasma membrane for virus assembly. The Journal of Biological Chemistry. PMID 30309983 DOI: 10.1074/Jbc.Ra118.003944 |
0.459 |
|
| 2018 |
Watanabe SM, Medina G, Eastep GN, Ghanam RH, Vlach J, Saad JS, Carter C. The matrix domain of the Gag protein from avian sarcoma virus contains a PI(4,5)P2-binding site that targets Gag to the cell periphery. The Journal of Biological Chemistry. PMID 30309982 DOI: 10.1074/Jbc.Ra118.003947 |
0.458 |
|
| 2018 |
Vlach J, Saad J, Eastep G, Ghanam R. NMR assignments of Rous sarcoma virus matrix protein (M domain) Journal of Back and Musculoskeletal Rehabilitation. DOI: 10.13018/Bmr27396 |
0.305 |
|
| 2017 |
Murphy RE, Samal AB, Vlach J, Saad JS. Solution Structure and Membrane Interaction of the Cytoplasmic Tail of HIV-1 gp41 Protein. Structure (London, England : 1993). PMID 29056482 DOI: 10.1016/J.Str.2017.09.010 |
0.438 |
|
| 2016 |
Agamasu C, Ghanam RH, Xu F, Sun Y, Chen Y, Saad JS. The Interplay Between Calmodulin and Membrane Interactions with the Pleckstrin Homology Domain of Akt. The Journal of Biological Chemistry. PMID 27872186 DOI: 10.1074/Jbc.M116.752816 |
0.377 |
|
| 2016 |
Chang BJ, Samal AB, Vlach J, Fernandez TF, Brooke D, Prevelige PE, Saad JS. Identification of the Calmodulin-Binding Domains of Fas Death Receptor. Plos One. 11: e0146493. PMID 26735300 DOI: 10.1371/Journal.Pone.0146493 |
0.328 |
|
| 2015 |
Agamasu C, Ghanam RH, Saad JS. Structural and Biophysical Characterization of the Interactions between Calmodulin and the Pleckstrin Homology Domain of Akt. The Journal of Biological Chemistry. 290: 27403-13. PMID 26391397 DOI: 10.1074/Jbc.M115.673939 |
0.364 |
|
| 2015 |
Saad JS, Muriaux DM. Editorial: Role of lipids in virus assembly. Frontiers in Microbiology. 6: 410. PMID 25999935 DOI: 10.3389/Fmicb.2015.00410 |
0.357 |
|
| 2015 |
Lampel A, Bram Y, Ezer A, Shaltiel-Kario R, Saad JS, Bacharach E, Gazit E. Targeting the Early Step of Building Block Organization in Viral Capsid Assembly. Acs Chemical Biology. PMID 25997366 DOI: 10.1021/Acschembio.5B00347 |
0.348 |
|
| 2015 |
Vlach J, Saad JS. Structural and molecular determinants of HIV-1 Gag binding to the plasma membrane. Frontiers in Microbiology. 6: 232. PMID 25852680 DOI: 10.3389/Fmicb.2015.00232 |
0.438 |
|
| 2014 |
Vlach J, Saad JS. HIV: a vicTIM. Trends in Microbiology. 22: 603-4. PMID 25438615 DOI: 10.1016/J.Tim.2014.09.008 |
0.389 |
|
| 2014 |
Vlach J, Samal AB, Saad JS. Solution structure of calmodulin bound to the binding domain of the HIV-1 matrix protein. The Journal of Biological Chemistry. 289: 8697-705. PMID 24500712 DOI: 10.1074/Jbc.M113.543694 |
0.454 |
|
| 2013 |
Fernandez TF, Samal AB, Bedwell GJ, Chen Y, Saad JS. Structural and biophysical characterization of the interactions between the death domain of Fas receptor and calmodulin. The Journal of Biological Chemistry. 288: 21898-908. PMID 23760276 DOI: 10.1074/Jbc.M113.471821 |
0.327 |
|
| 2013 |
Vlach J, Saad JS. Trio engagement via plasma membrane phospholipids and the myristoyl moiety governs HIV-1 matrix binding to bilayers. Proceedings of the National Academy of Sciences of the United States of America. 110: 3525-30. PMID 23401539 DOI: 10.1073/Pnas.1216655110 |
0.451 |
|
| 2012 |
Ghanam RH, Samal AB, Fernandez TF, Saad JS. Role of the HIV-1 Matrix Protein in Gag Intracellular Trafficking and Targeting to the Plasma Membrane for Virus Assembly. Frontiers in Microbiology. 3: 55. PMID 22363329 DOI: 10.3389/Fmicb.2012.00055 |
0.452 |
|
| 2011 |
Dearborn AD, Spilman MS, Damle PK, Chang JR, Monroe EB, Saad JS, Christie GE, Dokland T. The Staphylococcus aureus pathogenicity island 1 protein gp6 functions as an internal scaffold during capsid size determination. Journal of Molecular Biology. 412: 710-22. PMID 21821042 DOI: 10.1016/J.Jmb.2011.07.036 |
0.314 |
|
| 2011 |
Saad JS, Marzilli PA, Intini FP, Natile G, Marzilli LG. Single-stranded oligonucleotide adducts formed by Pt complexes favoring left-handed base canting: steric effect of flanking residues and relevance to DNA adducts formed by Pt anticancer drugs. Inorganic Chemistry. 50: 8608-20. PMID 21819051 DOI: 10.1021/Ic2011716 |
0.512 |
|
| 2011 |
Samal AB, Ghanam RH, Fernandez TF, Monroe EB, Saad JS. NMR, biophysical, and biochemical studies reveal the minimal Calmodulin binding domain of the HIV-1 matrix protein. The Journal of Biological Chemistry. 286: 33533-43. PMID 21799007 DOI: 10.1074/Jbc.M111.273623 |
0.431 |
|
| 2011 |
Saad JS, Benedetti M, Natile G, Marzilli LG. NMR studies of models having the Pt(d(GpG)) 17-membered macrocyclic ring formed in DNA by platinum anticancer drugs: Pt complexes with bulky chiral diamine ligands. Inorganic Chemistry. 50: 4559-71. PMID 21510625 DOI: 10.1021/Ic200259S |
0.524 |
|
| 2010 |
Ghanam RH, Fernandez TF, Fledderman EL, Saad JS. Binding of calmodulin to the HIV-1 matrix protein triggers myristate exposure. The Journal of Biological Chemistry. 285: 41911-20. PMID 20956522 DOI: 10.1074/Jbc.M110.179093 |
0.453 |
|
| 2010 |
Fledderman EL, Fujii K, Ghanam RH, Waki K, Prevelige PE, Freed EO, Saad JS. Myristate exposure in the human immunodeficiency virus type 1 matrix protein is modulated by pH. Biochemistry. 49: 9551-62. PMID 20886905 DOI: 10.1021/Bi101245J |
0.426 |
|
| 2010 |
Saad JS, Benedetti M, Natile G, Marzilli LG. Basic coordination chemistry relevant to DNA adducts formed by the cisplatin anticancer drug. NMR studies on compounds with sterically crowded chiral ligands. Inorganic Chemistry. 49: 5573-83. PMID 20496875 DOI: 10.1021/Ic100494F |
0.509 |
|
| 2010 |
Valentine KG, Peterson RW, Saad JS, Summers MF, Xu X, Ames JB, Wand AJ. Reverse micelle encapsulation of membrane-anchored proteins for solution NMR studies. Structure (London, England : 1993). 18: 9-16. PMID 20152148 DOI: 10.1016/J.Str.2009.11.010 |
0.581 |
|
| 2010 |
Hamard-Peron E, Juillard F, Saad JS, Roy C, Roingeard P, Summers MF, Darlix JL, Picart C, Muriaux D. Targeting of murine leukemia virus gag to the plasma membrane is mediated by PI(4,5)P2/PS and a polybasic region in the matrix. Journal of Virology. 84: 503-15. PMID 19828619 DOI: 10.1128/Jvi.01134-09 |
0.592 |
|
| 2009 |
Saad JS, Natile G, Marzilli LG. Origins of the distortions in the base pair step adjacent to platinum anticancer drug-DNA adducts. Fundamental NMR solution studies utilizing right-handed cross-link models having 5'- and 3'-flanking residues. Journal of the American Chemical Society. 131: 12314-24. PMID 19655752 DOI: 10.1021/Ja903787M |
0.528 |
|
| 2009 |
Hamard-Peron E, Juilliard F, Saad JS, Roy C, Roingeard P, Summers MF, Darlix JL, Picart C, Muriaux D. Targeting of MuLV gag to the plasma membrane is mediated by PI(4,5)P2 and phosphatidylserine Retrovirology. 6: O15. DOI: 10.1186/1742-4690-6-S2-O15 |
0.598 |
|
| 2008 |
Saad JS, Ablan SD, Ghanam RH, Kim A, Andrews K, Nagashima K, Soheilian F, Freed EO, Summers MF. Structure of the myristylated human immunodeficiency virus type 2 matrix protein and the role of phosphatidylinositol-(4,5)-bisphosphate in membrane targeting. Journal of Molecular Biology. 382: 434-47. PMID 18657545 DOI: 10.1016/J.Jmb.2008.07.027 |
0.61 |
|
| 2008 |
Saad J, Ablan S, Ghanam R, Kim A, Andrews K, Nagashima K, Freed E, Summers M. Solution structure of the HIV-2 myristoylated Matrix protein Journal of Back and Musculoskeletal Rehabilitation. DOI: 10.2210/Pdb2K4E/Pdb |
0.568 |
|
| 2007 |
Saad JS, Kim A, Ghanam RH, Dalton AK, Vogt VM, Wu Z, Lu W, Summers MF. Mutations that mimic phosphorylation of the HIV-1 matrix protein do not perturb the myristyl switch. Protein Science : a Publication of the Protein Society. 16: 1793-7. PMID 17656588 DOI: 10.1110/Ps.072987607 |
0.609 |
|
| 2007 |
Saad JS, Loeliger E, Luncsford P, Liriano M, Tai J, Kim A, Miller J, Joshi A, Freed EO, Summers MF. Point mutations in the HIV-1 matrix protein turn off the myristyl switch. Journal of Molecular Biology. 366: 574-85. PMID 17188710 DOI: 10.1016/J.Jmb.2006.11.068 |
0.629 |
|
| 2007 |
Saad JS, Loeliger E, Luncsford P, Liriano M, Tai J, Kim A, Miller J, Joshi A, Freed EO, Summers MF. Solution structure of L8A mutant of HIV-1 myristoylated matrix protein Journal of Back and Musculoskeletal Rehabilitation. DOI: 10.2210/Pdb2Jmg/Pdb |
0.573 |
|
| 2006 |
Saad JS, Miller J, Tai J, Kim A, Ghanam RH, Summers MF. Structural basis for targeting HIV-1 Gag proteins to the plasma membrane for virus assembly. Proceedings of the National Academy of Sciences of the United States of America. 103: 11364-9. PMID 16840558 DOI: 10.1073/Pnas.0602818103 |
0.62 |
|
| 2006 |
Saad J, Miller J, Tai J, Kim A, Ghanam R, Summers M. Backbone 1H, 13C, 15N Chemical Shift Assignments for HIV-1 myristoylated matrix protein Journal of Back and Musculoskeletal Rehabilitation. DOI: 10.13018/Bmr7309 |
0.571 |
|
| 2003 |
Benedetti M, Saad JS, Marzilli LG, Natile G. Chiral discrimination in the formation reaction and at equilibrium for N,N,N′9N′-tetramethyl-1,2-diaminocyclohexane-PtG2 complexes Dalton Transactions. 872-879. DOI: 10.1039/b210616g |
0.36 |
|
| 2002 |
Saad JS, Scarcia T, Natile G, Marzilli LG. Factors influencing conformer equilibria in retro models of cisplatin-DNA adducts as revealed by moderately dynamic (N,N'-dimethyl-2,3-diaminobutane)PtG(2) retro models (G = a guanine derivative). Inorganic Chemistry. 41: 4923-35. PMID 12230397 DOI: 10.1021/Ic011115M |
0.497 |
|
| 2002 |
Sullivan ST, Saad JS, Fanizzi FP, Marzilli LG. Dramatic 5'-residue effect on conformer distribution of short oligonucleotide retro models of the cisplatin-DNA cross-link: implications for the Lippard and cross-link distorted base pair steps present in cisplatin-DNA duplex adducts. Journal of the American Chemical Society. 124: 1558-9. PMID 11853413 DOI: 10.1021/Ja0121742 |
0.677 |
|
| 2002 |
Saad JS, Scarcia T, Shinozuka K, Natile G, Marzilli LG. Modification of second-sphere communication, leading to an unusually high abundance of the head-to-head conformer of cisplatin cross-link retro models. Inorganic Chemistry. 41: 546-57. PMID 11825082 DOI: 10.1021/Ic010758Z |
0.512 |
|
| 2002 |
Sullivan ST, Saad JS, Fanizzi FP, Marzilli LG. Dramatic 5′-residue effect on conformer distribution of short oligonucleotide retro models of the cisplatin-DNA cross-link: Implications for the lippard and cross-link distorted base pair steps present in cisplatin-DNA duplex adducts Journal of the American Chemical Society. 124: 1558-1559. DOI: 10.1021/ja0121742 |
0.644 |
|
| 2001 |
Marzilli LG, Saad JS, Kuklenyik Z, Keating KA, Xu Y. Relationship of solution and protein-bound structures of DNA duplexes with the major intrastrand cross-link lesions formed on cisplatin binding to DNA. Journal of the American Chemical Society. 123: 2764-70. PMID 11456962 DOI: 10.1021/Ja0007915 |
0.537 |
|
| Show low-probability matches. |