Elisabeth B. Binder - Publications

Affiliations: 
Max Planck Instute of Psychiatry/Emory, München, Bayern, Germany 
Area:
Psychiatric Genetics

254 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2022 Winter SM, Dittrich K, Dörr P, Overfeld J, Moebus I, Murray E, Karaboycheva G, Zimmermann C, Knop A, Voelkle M, Entringer S, Buss C, Haynes JD, Binder EB, Heim C. Immediate impact of child maltreatment on mental, developmental, and physical health trajectories. Journal of Child Psychology and Psychiatry, and Allied Disciplines. PMID 35266137 DOI: 10.1111/jcpp.13550  0.402
2021 Godara M, Silveira S, Matthäus H, Heim C, Voelkle M, Hecht M, Binder EB, Singer T. Investigating differential effects of socio-emotional and mindfulness-based online interventions on mental health, resilience and social capacities during the COVID-19 pandemic: The study protocol. Plos One. 16: e0256323. PMID 34735441 DOI: 10.1371/journal.pone.0256323  0.41
2021 Dammering F, Martins J, Dittrich K, Czamara D, Rex-Haffner M, Overfeld J, de Punder K, Buss C, Entringer S, Winter SM, Binder EB, Heim C. The pediatric buccal epigenetic clock identifies significant ageing acceleration in children with internalizing disorder and maltreatment exposure. Neurobiology of Stress. 15: 100394. PMID 34621920 DOI: 10.1016/j.ynstr.2021.100394  0.464
2021 Martins J, Czamara D, Sauer S, Rex-Haffner M, Dittrich K, Dörr P, de Punder K, Overfeld J, Knop A, Dammering F, Entringer S, Winter SM, Buss C, Heim C, Binder EB. Childhood adversity correlates with stable changes in DNA methylation trajectories in children and converges with epigenetic signatures of prenatal stress. Neurobiology of Stress. 15: 100336. PMID 34095363 DOI: 10.1016/j.ynstr.2021.100336  0.463
2021 Lopez JP, Brivio E, Santambrogio A, De Donno C, Kos A, Peters M, Rost N, Czamara D, Brückl TM, Roeh S, Pöhlmann ML, Engelhardt C, Ressle A, Stoffel R, Tontsch A, ... ... Binder EB, et al. Single-cell molecular profiling of all three components of the HPA axis reveals adrenal ABCB1 as a regulator of stress adaptation. Science Advances. 7. PMID 33571131 DOI: 10.1126/sciadv.abe4497  0.418
2021 Czamara D, Tissink E, Tuhkanen J, Martins J, Awaloff Y, Drake AJ, Khulan B, Palotie A, Winter SM, Nemeroff CB, Craighead WE, Dunlop BW, Mayberg HS, Kinkead B, Mathew SJ, ... ... Binder EB, et al. Combined effects of genotype and childhood adversity shape variability of DNA methylation across age. Translational Psychiatry. 11: 88. PMID 33526782 DOI: 10.1038/s41398-020-01147-z  0.697
2020 Entringer S, de Punder K, Overfeld J, Karaboycheva G, Dittrich K, Buss C, Winter SM, Binder EB, Heim C. Immediate and longitudinal effects of maltreatment on systemic inflammation in young children. Development and Psychopathology. 32: 1725-1731. PMID 33427162 DOI: 10.1017/S0954579420001686  0.454
2020 Daskalakis NP, Xu C, Bader HN, Chatzinakos C, Weber P, Makotkine I, Lehrner A, Bierer LM, Binder EB, Yehuda R. Intergenerational trauma is associated with expression alterations in glucocorticoid- and immune-related genes. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 33173192 DOI: 10.1038/s41386-020-00900-8  0.597
2020 Hagenaars SP, Coleman JRI, Choi SW, Gaspar H, Adams MJ, Howard DM, Hodgson K, Traylor M, Air TM, Andlauer TFM, Arolt V, Baune BT, Binder EB, Blackwood DHR, Boomsma DI, et al. Genetic comorbidity between major depression and cardio-metabolic traits, stratified by age at onset of major depression. American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics. PMID 32681593 DOI: 10.1002/Ajmg.B.32807  0.323
2020 Rantalainen V, Binder EB, Lahti-Pulkkinen M, Czamara D, Laivuori H, Villa PM, Girchenko P, Kvist T, Hämäläinen E, Kajantie E, Lahti J, Räikkönen K. Polygenic prediction of the risk of perinatal depressive symptoms. Depression and Anxiety. PMID 32627298 DOI: 10.1002/da.23066  0.336
2020 Kühnel A, Kroemer NB, Elbau IG, Czisch M, Sämann PG, Walter M, Binder EB. Psychosocial stress reactivity habituates following acute physiological stress. Human Brain Mapping. PMID 32597537 DOI: 10.1002/Hbm.25106  0.33
2020 Krontira AC, Cruceanu C, Binder EB. Glucocorticoids as Mediators of Adverse Outcomes of Prenatal Stress. Trends in Neurosciences. 43: 394-405. PMID 32459992 DOI: 10.1016/j.tins.2020.03.008  0.36
2020 Brückl TM, Spoormaker VI, Sämann PG, Brem AK, Henco L, Czamara D, Elbau I, Grandi NC, Jollans L, Kühnel A, Leuchs L, Pöhlchen D, Schneider M, Tontsch A, Keck ME, ... ... Binder EB, et al. The biological classification of mental disorders (BeCOME) study: a protocol for an observational deep-phenotyping study for the identification of biological subtypes. Bmc Psychiatry. 20: 213. PMID 32393358 DOI: 10.1186/S12888-020-02541-Z  0.308
2020 Bierer LM, Bader HN, Daskalakis NP, Lehrner A, Provençal N, Wiechmann T, Klengel T, Makotkine I, Binder EB, Yehuda R. Intergenerational Effects of Maternal Holocaust Exposure on Methylation. The American Journal of Psychiatry. appiajp201919060618. PMID 32312110 DOI: 10.1176/Appi.Ajp.2019.19060618  0.616
2020 Arloth J, Eraslan G, Andlauer TFM, Martins J, Iurato S, Kühnel B, Waldenberger M, Frank J, Gold R, Hemmer B, Luessi F, Nischwitz S, Paul F, Wiendl H, Gieger C, ... ... Binder EB, et al. DeepWAS: Multivariate genotype-phenotype associations by directly integrating regulatory information using deep learning. Plos Computational Biology. 16: e1007616. PMID 32012148 DOI: 10.1371/Journal.Pcbi.1007616  0.328
2019 Penner-Goeke S, Binder EB. Epigenetics and depression
. Dialogues in Clinical Neuroscience. 21: 397-405. PMID 31949407 DOI: 10.31887/DCNS.2019.21.4/ebinder  0.366
2019 Jia T, Chu C, Liu Y, van Dongen J, Papastergios E, Armstrong NJ, Bastin ME, Carrillo-Roa T, den Braber A, Harris M, Jansen R, Liu J, Luciano M, Ori APS, Roiz Santiañez R, ... ... Binder EB, et al. Epigenome-wide meta-analysis of blood DNA methylation and its association with subcortical volumes: findings from the ENIGMA Epigenetics Working Group. Molecular Psychiatry. PMID 31811260 DOI: 10.1038/S41380-019-0605-Z  0.325
2019 Jiang S, Postovit L, Cattaneo A, Binder EB, Aitchison KJ. Epigenetic Modifications in Stress Response Genes Associated With Childhood Trauma. Frontiers in Psychiatry. 10: 808. PMID 31780969 DOI: 10.3389/Fpsyt.2019.00808  0.398
2019 McLean SA, Ressler K, Koenen KC, Neylan T, Germine L, Jovanovic T, Clifford GD, Zeng D, An X, Linnstaedt S, Beaudoin F, House S, Bollen KA, Musey P, Hendry P, ... ... Binder E, et al. The AURORA Study: a longitudinal, multimodal library of brain biology and function after traumatic stress exposure. Molecular Psychiatry. PMID 31745239 DOI: 10.1038/S41380-019-0581-3  0.34
2019 Forstner AJ, Awasthi S, Wolf C, Maron E, Erhardt A, Czamara D, Eriksson E, Lavebratt C, Allgulander C, Friedrich N, Becker J, Hecker J, Rambau S, Conrad R, Geiser F, ... ... Binder EB, et al. Genome-wide association study of panic disorder reveals genetic overlap with neuroticism and depression. Molecular Psychiatry. PMID 31712720 DOI: 10.1038/S41380-019-0590-2  0.307
2019 Thomas M, Coope A, Falkenberg C, Dunlop BW, Czamara D, Provencal N, Craighead WE, Mayberg HS, Nemeroff CB, Binder EB, Nieratschker V. Investigation of MORC1 DNA methylation as biomarker of early life stress and depressive symptoms. Journal of Psychiatric Research. 120: 154-162. PMID 31683097 DOI: 10.1016/j.jpsychires.2019.10.019  0.504
2019 Raffington L, Czamara D, Mohn JJ, Falck J, Schmoll V, Heim C, Binder EB, Shing YL. Stable longitudinal associations of family income with children's hippocampal volume and memory persist after controlling for polygenic scores of educational attainment. Developmental Cognitive Neuroscience. 40: 100720. PMID 31678692 DOI: 10.1016/j.dcn.2019.100720  0.479
2019 Aristizabal MJ, Anreiter I, Halldorsdottir T, Odgers CL, McDade TW, Goldenberg A, Mostafavi S, Kobor MS, Binder EB, Sokolowski MB, O'Donnell KJ. Biological embedding of experience: A primer on epigenetics. Proceedings of the National Academy of Sciences of the United States of America. PMID 31624126 DOI: 10.1073/Pnas.1820838116  0.313
2019 Ing A, Sämann PG, Chu C, Tay N, Biondo F, Robert G, Jia T, Wolfers T, Desrivières S, Banaschewski T, Bokde ALW, Bromberg U, Büchel C, Conrod P, Fadai T, ... ... Binder E, et al. Identification of neurobehavioural symptom groups based on shared brain mechanisms. Nature Human Behaviour. PMID 31591521 DOI: 10.1038/S41562-019-0738-8  0.315
2019 Glanville KP, Coleman JRI, Hanscombe KB, Euesden J, Choi SW, Purves KL, Breen G, Air TM, Andlauer TFM, Baune BT, Binder EB, Blackwood DHR, Boomsma DI, Buttenschøn HN, Colodro-Conde L, et al. Classical Human Leukocyte Antigen Alleles and C4 Haplotypes Are Not Significantly Associated With Depression. Biological Psychiatry. PMID 31570195 DOI: 10.1016/J.Biopsych.2019.06.031  0.335
2019 Provençal N, Arloth J, Cattaneo A, Anacker C, Cattane N, Wiechmann T, Röh S, Ködel M, Klengel T, Czamara D, Müller NS, Lahti J, Räikkönen K, Pariante CM, ... Binder EB, et al. Glucocorticoid exposure during hippocampal neurogenesis primes future stress response by inducing changes in DNA methylation. Proceedings of the National Academy of Sciences of the United States of America. PMID 31399550 DOI: 10.1073/Pnas.1820842116  0.353
2019 Lebow MA, Schroeder M, Tsoory M, Holzman-Karniel D, Mehta D, Ben-Dor S, Gil S, Bradley B, Smith AK, Jovanovic T, Ressler KJ, Binder EB, Chen A. Glucocorticoid-induced leucine zipper "quantifies" stressors and increases male susceptibility to PTSD. Translational Psychiatry. 9: 178. PMID 31346158 DOI: 10.1038/S41398-019-0509-3  0.356
2019 Kazmi N, Sharp GC, Reese SE, Vehmeijer FO, Lahti J, Page CM, Zhang W, Rifas-Shiman SL, Rezwan FI, Simpkin AJ, Burrows K, Richardson TG, Santos Ferreira DL, Fraser A, Harmon QE, ... ... Binder EB, et al. Hypertensive Disorders of Pregnancy and DNA Methylation in Newborns. Hypertension (Dallas, Tex. : 1979). HYPERTENSIONAHA11912. PMID 31230546 DOI: 10.1161/Hypertensionaha.119.12634  0.32
2019 Elbau IG, Cruceanu C, Binder EB. Genetics of Resilience: Gene-by-Environment Interaction Studies as a Tool to Dissect Mechanisms of Resilience. Biological Psychiatry. PMID 31202489 DOI: 10.1016/j.biopsych.2019.04.025  0.303
2019 Czamara D, Eraslan G, Page CM, Lahti J, Lahti-Pulkkinen M, Hämäläinen E, Kajantie E, Laivuori H, Villa PM, Reynolds RM, Nystad W, Håberg SE, London SJ, O'Donnell KJ, Garg E, ... ... Binder EB, et al. Integrated analysis of environmental and genetic influences on cord blood DNA methylation in new-borns. Nature Communications. 10: 2548. PMID 31186427 DOI: 10.1038/S41467-019-10461-0  0.316
2019 Wiechmann T, Röh S, Sauer S, Czamara D, Arloth J, Ködel M, Beintner M, Knop L, Menke A, Binder EB, Provençal N. Identification of dynamic glucocorticoid-induced methylation changes at the FKBP5 locus. Clinical Epigenetics. 11: 83. PMID 31122292 DOI: 10.1186/s13148-019-0682-5  0.348
2019 Zannas AS, Jia M, Hafner K, Baumert J, Wiechmann T, Pape JC, Arloth J, Ködel M, Martinelli S, Roitman M, Röh S, Haehle A, Emeny RT, Iurato S, Carrillo-Roa T, ... ... Binder EB, et al. Epigenetic upregulation of FKBP5 by aging and stress contributes to NF-κB-driven inflammation and cardiovascular risk. Proceedings of the National Academy of Sciences of the United States of America. PMID 31113877 DOI: 10.1073/Pnas.1816847116  0.363
2019 Mehta D, Rex-Haffner M, Søndergaard HB, Pinborg A, Binder EB, Frokjaer VG. Genome-wide gene expression in a pharmacological hormonal transition model and its relation to depressive symptoms. Acta Psychiatrica Scandinavica. PMID 31099405 DOI: 10.1111/acps.13038  0.338
2019 Küpers LK, Monnereau C, Sharp GC, Yousefi P, Salas LA, Ghantous A, Page CM, Reese SE, Wilcox AJ, Czamara D, Starling AP, Novoloaca A, Lent S, Roy R, Hoyo C, ... ... Binder EB, et al. Meta-analysis of epigenome-wide association studies in neonates reveals widespread differential DNA methylation associated with birthweight. Nature Communications. 10: 1893. PMID 31015461 DOI: 10.1038/S41467-019-09671-3  0.304
2019 Athreya AP, Neavin D, Carrillo-Roa T, Skime M, Biernacka J, Frye MA, Rush AJ, Wang L, Binder EB, Iyer RK, Weinshilboum RM, Bobo WV. Pharmacogenomics-Driven Prediction of Antidepressant Treatment Outcomes: A Machine Learning Approach with Multi-Trial Replication. Clinical Pharmacology and Therapeutics. PMID 31012492 DOI: 10.1002/Cpt.1482  0.309
2019 Ramo-Fernández L, Boeck C, Koenig AM, Schury K, Binder EB, Gündel H, Fegert JM, Karabatsiakis A, Kolassa IT. The effects of childhood maltreatment on epigenetic regulation of stress-response associated genes: an intergenerational approach. Scientific Reports. 9: 983. PMID 31000782 DOI: 10.1038/s41598-018-36689-2  0.386
2019 Piechaczek CE, Greimel E, Feldmann L, Pehl V, Allgaier AK, Frey M, Freisleder FJ, Halldorsdottir T, Binder EB, Ising M, Schulte-Körne G. Interactions between FKBP5 variation and environmental stressors in adolescent Major Depression. Psychoneuroendocrinology. 106: 28-37. PMID 30953930 DOI: 10.1016/J.Psyneuen.2019.03.025  0.37
2019 Halldorsdottir T, Kurtoic D, Müller-Myhsok B, Binder EB, Blair C. Neurobiology of Self-Regulation: Longitudinal Influence of FKBP5 and Intimate Partner Violence on Emotional and Cognitive Development in Childhood. The American Journal of Psychiatry. appiajp201918091018. PMID 30947533 DOI: 10.1176/Appi.Ajp.2019.18091018  0.321
2019 Halldorsdottir T, Piechaczek C, Soares de Matos AP, Czamara D, Pehl V, Wagenbuechler P, Feldmann L, Quickenstedt-Reinhardt P, Allgaier AK, Freisleder FJ, Greimel E, Kvist T, Lahti J, Räikkönen K, Rex-Haffner M, ... ... Binder EB, et al. Polygenic Risk: Predicting Depression Outcomes in Clinical and Epidemiological Cohorts of Youths. The American Journal of Psychiatry. appiajp201918091014. PMID 30947532 DOI: 10.1176/Appi.Ajp.2019.18091014  0.343
2019 Bin Wei Y, McCarthy M, Ren H, Carrillo-Roa T, Shekhtman T, DeModena A, Liu JJ, Leckband SG, Mors O, Rietschel M, Henigsberg N, Cattaneo A, Binder EB, Aitchison KJ, Kelsoe JR. A functional variant in the serotonin receptor 7 gene (HTR7), rs7905446, is associated with good response to SSRIs in bipolar and unipolar depression. Molecular Psychiatry. PMID 30874608 DOI: 10.1038/S41380-019-0397-1  0.379
2019 Toepfer P, O Donnell KJ, Entringer S, Heim CM, Lin DTS, MacIsaac JL, Kobor MS, Meaney MJ, Provençal N, Binder EB, Wadhwa PD, Buss C. A Role of Oxytocin Receptor Gene Brain Tissue Expression Quantitative Trait Locus rs237895 in the Intergenerational Transmission of the Effects of Maternal Childhood Maltreatment. Journal of the American Academy of Child and Adolescent Psychiatry. PMID 30858011 DOI: 10.1016/J.Jaac.2019.03.006  0.534
2019 Rowson SA, Bekhbat M, Kelly SD, Binder EB, Hyer MM, Shaw G, Bent MA, Hodes G, Tharp G, Weinshenker D, Qin Z, Neigh GN. Chronic adolescent stress sex-specifically alters the hippocampal transcriptome in adulthood. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 30710108 DOI: 10.1038/S41386-019-0321-Z  0.597
2019 Zimmermann CA, Arloth J, Santarelli S, Löschner A, Weber P, Schmidt MV, Spengler D, Binder EB. Stress dynamically regulates co-expression networks of glucocorticoid receptor-dependent MDD and SCZ risk genes. Translational Psychiatry. 9: 41. PMID 30696808 DOI: 10.1038/S41398-019-0373-1  0.388
2019 Toepfer P, O'Donnell KJ, Entringer S, Garg E, Heim CM, Lin DTS, MacIsaac JL, Kobor MS, Meaney MJ, Provençal N, Binder EB, Wadhwa PD, Buss C. Dynamic DNA methylation changes in the maternal oxytocin gene locus (OXT) during pregnancy predict postpartum maternal intrusiveness. Psychoneuroendocrinology. 103: 156-162. PMID 30690225 DOI: 10.1016/J.Psyneuen.2019.01.013  0.502
2019 Binder EB. [Environment and epigenetics]. Der Nervenarzt. PMID 30643952 DOI: 10.1007/s00115-018-0657-3  0.322
2019 Overfeld J, Buss C, Punder Kd, Winter S, Haynes J, Binder EB, Heim C. Immediate biological embedding of maltreatment in children: Moderating effects of FK506 binding protein 5 (FKBP5) gene on cortisol reactivity and amygdala volume in children aged 3–5 years Psychoneuroendocrinology. 107: 64-64. DOI: 10.1016/J.Psyneuen.2019.07.185  0.48
2019 Dammering F, Martins J, Hoffmann F, Provencal N, Punder Kd, Overfeld J, Czamara D, Rex-Haffner M, McEwen L, Kobor M, Winter S, Buss C, Entringer S, Binder E, Heim C. Psychiatric symptom severity mediates the effect of adversity on epigenetic aging in children aged 3-5 years Psychoneuroendocrinology. 107: 30-30. DOI: 10.1016/J.Psyneuen.2019.07.084  0.499
2019 Overfeld J, Buss C, Punder Kd, Winter S, Haynes J, Binder E, Heim C. Childhood maltreatment severity is associated with smaller total brain size in preschool age children Psychoneuroendocrinology. 107: 5-6. DOI: 10.1016/J.Psyneuen.2019.07.012  0.475
2019 Karaboycheva GD, Punder Kd, Overfeld J, Doerr P, Dittrich K, Murray E, Binder E, Winter S, Entringer S, Heim C. Intestinal dysbiosis in maltreated children is associated with concentrations of salivary cortisol, C-reactive protein and with depressive symptoms Psychoneuroendocrinology. 107: 3-3. DOI: 10.1016/J.Psyneuen.2019.07.007  0.509
2019 Dammering F, McEwen L, Provencal N, Punder Kd, Overfeld J, Martins J, Czamara D, Rex-Haffner M, Hoffmann F, Kobor M, Buss C, Winter S, Entringer S, Binder E, Heim C. Bidirectional effect of early adversity on epigenetic ageing in children: Mediation by C-reactive protein and moderation by FKBP5 gene and cortisol status Psychoneuroendocrinology. 100. DOI: 10.1016/J.Psyneuen.2018.12.169  0.511
2019 Toepfer P, O’Donnell KJ, Entringer S, Heim CM, Lin DT, MacIsaac JL, Kobor MS, Meaney MJ, Provencal N, Binder EB, Wadhwa PD, Buss C. OXTR brain tissue expression quantitative locus rs237895 moderates the association between maternal childhood maltreatment and non-optimal maternal behavior with implications for offspring socio-emotional development and attachment security Psychoneuroendocrinology. 100: S48. DOI: 10.1016/J.Psyneuen.2018.12.167  0.499
2019 Shaw GA, Bekhbat M, Rowson SA, Bent MA, Hodes G, Binder E, Neigh G. Female wistar rats with a history of chronic adolescent stress demonstrate decreased hippocampal DNA methylation in adulthood Psychoneuroendocrinology. 100: S25. DOI: 10.1016/J.Psyneuen.2018.12.093  0.583
2019 Punder Kd, Overfeld J, Karaboycheva G, Winter S, Buss C, Binder EB, Heim C. Elevated C-reactive protein levels in children aged 3–5 years with verified exposure to maltreatment: Sex differences and association with depressive symptoms Psychoneuroendocrinology. 100. DOI: 10.1016/J.Psyneuen.2018.12.089  0.524
2019 Penner-Goeke S, Roeh S, Jakovcevski M, Binder E. S57Identifying Glucocorticoid Receptor Mediated Mechanisms Of Polygene-Environment Interactions Involved In Stress Sensitivity European Neuropsychopharmacology. 29. DOI: 10.1016/J.Euroneuro.2019.08.058  0.314
2019 Kero H, Raikkonen K, Lahti M, Cattaneo A, Czamara D, Binder E, Lahti J. FoxO1 variation modifies associations between maternal depression and anxiety during pregnancy and offspring psychiatric problems in early childhood European Neuropsychopharmacology. 29. DOI: 10.1016/J.Euroneuro.2019.08.011  0.328
2019 Freitag CM, Binder E. Epigenetic findings in childhood onset psychiatric disorders European Neuropsychopharmacology. 29: 1036-1036. DOI: 10.1016/J.Euroneuro.2018.07.034  0.31
2019 Czamara D, Eraslan G, Suarez A, Girchenko P, Lahti J, Lahti M, Hämäläinen E, Kajantie E, Laivuori H, Reynolds RM, Kondofersky I, Müller NS, Theis FJ, Räikkönen K, Binder EB. WHAT SHAPES THE CHILD'S EPIGENOME: GENOTYPE, PRENATAL ENVIRONMENT OR BOTH? European Neuropsychopharmacology. 29: S985. DOI: 10.1016/j.euroneuro.2017.08.363  0.342
2019 Awaloff Y, Provencal N, Carrillo-Roa T, Halldorsdottir T, Boadie D, Mayberg H, Craighed E, Czamara D, Binder E. Interactions Between Genotype And Environment Have A Strong Effect On Variability In Dna Methylation In Psychiatric Patients European Neuropsychopharmacology. 29. DOI: 10.1016/J.Euroneuro.2017.08.361  0.357
2019 Binder E, Burmeister M. Mechanisms of Early Adversity Associated Increases In Risk For Psychiatric Disorders European Neuropsychopharmacology. 29: S746-S747. DOI: 10.1016/j.euroneuro.2017.06.085  0.395
2019 de KP, Overfeld J, Karaboycheva G, Dittrich K, Winter SM, Buss C, Binder EB, Entringer S, Heim C. Abstract #4336 C-reactive protein levels in children aged 3–5 years with verified exposure to maltreatment: Sex differences and association with depression Brain Behavior and Immunity. 81: 35. DOI: 10.1016/J.Bbi.2019.08.119  0.514
2018 Mehta D, Rex-Haffner M, Søndergaard HB, Pinborg A, Binder EB, Frokjaer VG. Evidence for oestrogen sensitivity in perinatal depression: pharmacological sex hormone manipulation study. The British Journal of Psychiatry : the Journal of Mental Science. 1-9. PMID 30457060 DOI: 10.1192/bjp.2018.234  0.344
2018 Pape JC, Carrillo-Roa T, Rothbaum BO, Nemeroff CB, Czamara D, Zannas AS, Iosifescu D, Mathew SJ, Neylan TC, Mayberg HS, Dunlop BW, Binder EB. DNA methylation levels are associated with CRF receptor antagonist treatment outcome in women with post-traumatic stress disorder. Clinical Epigenetics. 10: 136. PMID 30390684 DOI: 10.1186/s13148-018-0569-x  0.51
2018 Kelley ME, Dunlop BW, Nemeroff CB, Lori A, Carrillo-Roa T, Binder EB, Kutner MH, Rivera VA, Craighead WE, Mayberg HS. Response rate profiles for major depressive disorder: Characterizing early response and longitudinal nonresponse. Depression and Anxiety. PMID 30260539 DOI: 10.1002/da.22832  0.454
2018 Elbau IG, Brücklmeier B, Uhr M, Arloth J, Czamara D, Spoormaker VI, Czisch M, Stephan KE, Binder EB, Sämann PG. The brain's hemodynamic response function rapidly changes under acute psychosocial stress in association with genetic and endocrine stress response markers. Proceedings of the National Academy of Sciences of the United States of America. PMID 30201713 DOI: 10.1073/pnas.1804340115  0.363
2018 Engel M, Eggert C, Kaplick PM, Eder M, Röh S, Tietze L, Namendorf C, Arloth J, Weber P, Rex-Haffner M, Geula S, Jakovcevski M, Hanna JH, Leshkowitz D, Uhr M, ... ... Binder EB, et al. The Role of mA/m-RNA Methylation in Stress Response Regulation. Neuron. 99: 389-403.e9. PMID 30048615 DOI: 10.1016/J.Neuron.2018.07.009  0.332
2018 Roeh S, Wiechmann T, Sauer S, Ködel M, Binder EB, Provençal N. HAM-TBS: high-accuracy methylation measurements via targeted bisulfite sequencing. Epigenetics & Chromatin. 11: 39. PMID 29973294 DOI: 10.1186/s13072-018-0209-x  0.32
2018 Mehta D, Bruenig D, Lawford B, Harvey W, Carrillo-Roa T, Morris CP, Jovanovic T, Young RM, Binder EB, Voisey J. Accelerated DNA methylation aging and increased resilience in veterans: The biological cost for soldiering on. Neurobiology of Stress. 8: 112-119. PMID 29888306 DOI: 10.1016/J.Ynstr.2018.04.001  0.31
2018 Zannas AS, Arloth J, Carrillo-Roa T, Iurato S, Röh S, Ressler KJ, Nemeroff CB, Smith AK, Bradley B, Heim C, Menke A, Lange JF, Brückl T, Ising M, Wray NR, ... ... Binder EB, et al. Correction to: Lifetime stress accelerates epigenetic aging in an urban, African American cohort: relevance of glucocorticoid signaling. Genome Biology. 19: 61. PMID 29792225 DOI: 10.1186/S13059-018-1441-1  0.556
2018 Suarez A, Lahti J, Czamara D, Lahti-Pulkkinen M, Knight AK, Girchenko P, Hämäläinen E, Kajantie E, Lipsanen J, Laivuori H, Villa PM, Reynolds RM, Smith AK, Binder EB, Räikkönen K. The Epigenetic Clock at Birth: Associations With Maternal Antenatal Depression and Child Psychiatric Problems. Journal of the American Academy of Child and Adolescent Psychiatry. 57: 321-328.e2. PMID 29706161 DOI: 10.1016/j.jaac.2018.02.011  0.347
2018 Wray NR, Ripke S, Mattheisen M, Trzaskowski M, Byrne EM, Abdellaoui A, Adams MJ, Agerbo E, Air TM, Andlauer TMF, Bacanu SA, Bækvad-Hansen M, Beekman AFT, Bigdeli TB, Binder EB, et al. Genome-wide association analyses identify 44 risk variants and refine the genetic architecture of major depression. Nature Genetics. PMID 29700475 DOI: 10.1038/S41588-018-0090-3  0.359
2018 Koenig AM, Ramo-Fernández L, Boeck C, Umlauft M, Pauly M, Binder EB, Kirschbaum C, Gündel H, Karabatsiakis A, Kolassa IT. Intergenerational gene × environment interaction of FKBP5 and childhood maltreatment on hair steroids. Psychoneuroendocrinology. 92: 103-112. PMID 29674169 DOI: 10.1016/J.Psyneuen.2018.04.002  0.337
2018 Matosin N, Halldorsdottir T, Binder EB. Understanding the Molecular Mechanisms Underpinning Gene by Environment Interactions in Psychiatric Disorders: The FKBP5 Model. Biological Psychiatry. PMID 29573791 DOI: 10.1016/j.biopsych.2018.01.021  0.384
2018 Rampp C, Eichelkraut A, Best J, Czamara D, Rex-Haffner M, Uhr M, Binder EB, Menke A. Sex-related differential response to dexamethasone in endocrine and immune measures in depressed in-patients and healthy controls. Journal of Psychiatric Research. 98: 107-115. PMID 29331929 DOI: 10.1016/j.jpsychires.2017.12.020  0.341
2018 Naik RR, Sotnikov SV, Diepold RP, Iurato S, Markt PO, Bultmann A, Brehm N, Mattheus T, Lutz B, Erhardt A, Binder EB, Schmidt U, Holsboer F, Landgraf R, Czibere L. Polymorphism in Tmem132d regulates expression and anxiety-related behavior through binding of RNA polymerase II complex. Translational Psychiatry. 8: 1. PMID 29317594 DOI: 10.1038/S41398-017-0025-2  0.344
2018 Cattaneo A, Cattane N, Malpighi C, Czamara D, Suarez A, Mariani N, Kajantie E, Luoni A, Eriksson JG, Lahti J, Mondelli V, Dazzan P, Räikkönen K, Binder EB, Riva MA, et al. FoxO1, A2M, and TGF-β1: three novel genes predicting depression in gene X environment interactions are identified using cross-species and cross-tissues transcriptomic and miRNomic analyses. Molecular Psychiatry. PMID 29302075 DOI: 10.1038/s41380-017-0002-4  0.384
2018 Criado-Marrero M, Rein T, Binder EB, Porter JT, Koren J, Blair LJ. Hsp90 and FKBP51: complex regulators of psychiatric diseases. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 373. PMID 29203717 DOI: 10.1098/Rstb.2016.0532  0.4
2018 Pape J, Carrillo-Roa T, Wiechmann T, Roeh S, Rothbaum B, Nemeroff C, Czamara D, Zannas A, Iosifescu D, Mathew S, Neylan T, Mayberg H, Dunlop B, Binder E. F179. Epigenetic Biomarkers in Women With Posttraumatic Stress Disorder After CRF1 Receptor Antagonist Treatment Biological Psychiatry. 83. DOI: 10.1016/J.Biopsych.2018.02.793  0.459
2017 Binder EB. Dissecting the molecular mechanisms of gene x environment interactions: implications for diagnosis and treatment of stress-related psychiatric disorders. European Journal of Psychotraumatology. 8: 1412745. PMID 29372006 DOI: 10.1080/20008198.2017.1412745  0.368
2017 Carrillo-Roa T, Labermaier C, Weber P, Herzog DP, Lareau C, Santarelli S, Wagner KV, Rex-Haffner M, Harbich D, Scharf SH, Nemeroff CB, Dunlop BW, Craighead WE, Mayberg HS, Schmidt MV, ... ... Binder EB, et al. Common genes associated with antidepressant response in mouse and man identify key role of glucocorticoid receptor sensitivity. Plos Biology. 15: e2002690. PMID 29283992 DOI: 10.1371/Journal.Pbio.2002690  0.49
2017 Iurato S, Carrillo-Roa T, Arloth J, Czamara D, Diener-Hölzl L, Lange J, Müller-Myhsok B, Binder EB, Erhardt A. "DNA Methylation signatures in panic disorder". Translational Psychiatry. 7: 1287. PMID 29249830 DOI: 10.1038/s41398-017-0026-1  0.304
2017 O'Connell CP, Goldstein-Piekarski AN, Nemeroff CB, Schatzberg AF, Debattista C, Carrillo-Roa T, Binder EB, Dunlop BW, Craighead WE, Mayberg HS, Williams LM. Antidepressant Outcomes Predicted by Genetic Variation in Corticotropin-Releasing Hormone Binding Protein. The American Journal of Psychiatry. appiajp201717020172. PMID 29241359 DOI: 10.1176/Appi.Ajp.2017.17020172  0.393
2017 Harms MB, Birn R, Provencal N, Wiechmann T, Binder EB, Giakas SW, Roeber BJ, Pollak SD. Early life stress, FK506 binding protein 5 gene (FKBP5) methylation, and inhibition-related prefrontal function: A prospective longitudinal study. Development and Psychopathology. 29: 1895-1903. PMID 29162190 DOI: 10.1017/S095457941700147X  0.364
2017 Breen MS, Tylee DS, Maihofer AX, Neylan TC, Mehta D, Binder E, Chandler SD, Hess JL, Kremen WS, Risbrough VB, Woelk CH, Baker DG, Nievergelt CM, Tsuang MT, Buxbaum JD, et al. PTSD Blood Transcriptome Mega-Analysis: Shared Inflammatory Pathways Across Biological Sex and Modes of Trauma. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 28925389 DOI: 10.1038/Npp.2017.220  0.322
2017 Dunlop BW, Binder EB, Iosifescu D, Mathew SJ, Neylan TC, Pape JC, Carrillo-Roa T, Green C, Kinkead B, Grigoriadis D, Rothbaum BO, Nemeroff CB, Mayberg HS. Corticotropin-Releasing Factor Receptor 1 Antagonism Is Ineffective for Women With Posttraumatic Stress Disorder. Biological Psychiatry. PMID 28793974 DOI: 10.1016/j.biopsych.2017.06.024  0.693
2017 Agís-Balboa RC, Pinhero P, Rebola N, Kerimoglu C, Benito E, Gertig M, Bahari-Javan S, Jain G, Burkhardt S, Delalle I, Jatzko A, Dettenhofer M, Zunszain PA, Schmitt A, Falkai P, ... ... Binder EB, et al. Formin 2 links neuropsychiatric phenotypes at young age to an increased risk for dementia. The Embo Journal. PMID 28768717 DOI: 10.15252/Embj.201796821  0.302
2017 Dedic N, Pöhlmann ML, Richter JS, Mehta D, Czamara D, Metzger MW, Dine J, Bedenk BT, Hartmann J, Wagner KV, Jurik A, Almli LM, Lori A, Moosmang S, Hofmann F, ... ... Binder EB, et al. Cross-disorder risk gene CACNA1C differentially modulates susceptibility to psychiatric disorders during development and adulthood. Molecular Psychiatry. PMID 28696432 DOI: 10.1038/Mp.2017.133  0.393
2017 Halldorsdottir T, de Matos APS, Awaloff Y, Arnarson EÖ, Craighead WE, Binder EB. FKBP5 moderation of the relationship between childhood trauma and maladaptive emotion regulation strategies in adolescents. Psychoneuroendocrinology. 84: 61-65. PMID 28654774 DOI: 10.1016/j.psyneuen.2017.06.012  0.347
2017 Emeny RT, Baumert J, Zannas AS, Kunze S, Wahl S, Iurato S, Arloth J, Erhardt A, Balsevich G, Schmidt MV, Weber P, Kretschmer A, Pfeiffer L, Kruse J, Strauch K, ... ... Binder EB, et al. Anxiety Associated Increased CpG Methylation In The Promoter of Asb1: A Translational Approach Evidenced By Epidemiological And Clinical Studies And A Murine Model. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 28540928 DOI: 10.1038/npp.2017.102  0.381
2017 Freytag V, Carrillo-Roa T, Milnik A, Sämann PG, Vukojevic V, Coynel D, Demougin P, Egli T, Gschwind L, Jessen F, Loos E, Maier W, Riedel-Heller SG, Scherer M, Vogler C, ... ... Binder EB, et al. A peripheral epigenetic signature of immune system genes is linked to neocortical thickness and memory. Nature Communications. 8: 15193. PMID 28443631 DOI: 10.1038/Ncomms15193  0.342
2017 Binder EB. Understanding gene × early adversity interactions: possibilities for insight in the biology of psychiatric disorders. European Archives of Psychiatry and Clinical Neuroscience. PMID 28271247 DOI: 10.1007/s00406-017-0775-0  0.325
2017 Santarelli S, Zimmermann C, Kalideris G, Lesuis SL, Arloth J, Uribe A, Dournes C, Balsevich G, Hartmann J, Masana M, Binder EB, Spengler D, Schmidt MV. An adverse early life environment can enhance stress resilience in adulthood. Psychoneuroendocrinology. 78: 213-221. PMID 28219813 DOI: 10.1016/J.Psyneuen.2017.01.021  0.345
2017 Maddox SA, Kilaru V, Shin J, Jovanovic T, Almli LM, Dias BG, Norrholm SD, Fani N, Michopoulos V, Ding Z, Conneely KN, Binder EB, Ressler KJ, Smith AK. Estrogen-dependent association of HDAC4 with fear in female mice and women with PTSD. Molecular Psychiatry. PMID 28093566 DOI: 10.1038/Mp.2016.250  0.36
2017 Toepfer P, ÓDonnell KJ, Heim CM, Lin DT, MacIsaac JL, Kobor MS, Meaney MJ, Provencal N, Binder EB, Entringer S, Wadhwa PD, Buss C. Dynamic DNA methylation changes in the oxytocin locus (OXT) during pregnancy are associated with maternal parenting behavior Psychoneuroendocrinology. 83: 25. DOI: 10.1016/J.Psyneuen.2017.07.306  0.485
2017 Carrillo-Roa T, Boadie D, McGrath C, Müller-Myhsok B, Craighed E, Mayberg H, Binder E. Polygenic Scores Derived From Neuroimaging Endophenotypes Predict Outcomes To Psychotherapy And Medication Treatments For Major Depressive Disorder European Neuropsychopharmacology. 27. DOI: 10.1016/J.Euroneuro.2016.09.576  0.346
2017 Cruceanu C, Matosin N, Binder EB. Interactions of early-life stress with the genome and epigenome: from prenatal stress to psychiatric disorders Current Opinion in Behavioral Sciences. 14: 167-171. DOI: 10.1016/j.cobeha.2017.04.001  0.372
2017 Clive M, Jones I, Wilcox H, Eaton W, Eck KV, Binder E, Osborne L, Payne J, Frokjaer V, Kaminsky Z. 357. Stress Vulnerability and Epigenetic Variation of a Suicide Biomarker Gene, Molecular Regulation and Neuroimaging Consequences of SKA2 Biological Psychiatry. 81. DOI: 10.1016/J.Biopsych.2017.02.374  0.337
2017 Wingo A, Lori A, Gillespie C, Kerley K, Jovanovic T, Binder E, Bradley B, Ressler K. 230. Transcriptome-wide Analysis Identified Differential Expression of PID1, a Gene Implicated in Insulin Resistance, in High versus Low Psychological Resilience Biological Psychiatry. 81: S94-S95. DOI: 10.1016/J.Biopsych.2017.02.244  0.593
2017 Kaminsky Z, Jones I, Bakker A, Wadhwa P, Entringer S, Osborne L, Binder E, Frokjaer V, Buss C, Payne J. 561. Discovery, Replication, and Application of an Epigenetic Biomarker Model to the Prediction of Postpartum Depression and Neuroimaging Endophenotypes Biological Psychiatry. 81: S227. DOI: 10.1016/J.Biopsych.2017.02.1169  0.303
2017 Pape J, Carrillo-Roa T, Iosifescu D, Mathew S, Neylan T, Nemeroff C, Mayberg H, Dunlop B, Binder E. 549. DNA Methylation Biomarkers and Treatment Effects of a Corticotropin Releasing Hormone Type 1 Receptor Antagonist in a Biologically-Defined Subset of PTSD-Patients Biological Psychiatry. 81. DOI: 10.1016/J.Biopsych.2017.02.1157  0.453
2017 Yehuda R, Bierer LM, Bader HN, Daskalakis NP, Klengel T, Binder E. 90. Second Generation Effects of Trauma: Evidence for Developmental Programming Biological Psychiatry. 81: S38. DOI: 10.1016/J.Biopsych.2017.02.102  0.577
2016 Toepfer P, Heim C, Entringer S, Binder E, Wadhwa P, Buss C. Oxytocin pathways in the intergenerational transmission of maternal early life stress. Neuroscience and Biobehavioral Reviews. 73: 293-308. PMID 28027955 DOI: 10.1016/J.Neubiorev.2016.12.026  0.555
2016 Piyasena C, Cartier J, Provençal N, Wiechmann T, Khulan B, Sunderasan R, Menon G, Seckl JR, Reynolds RM, Binder EB, Drake AJ. Dynamic Changes in DNA Methylation Occur during the First Year of Life in Preterm Infants. Frontiers in Endocrinology. 7: 158. PMID 28018293 DOI: 10.3389/fendo.2016.00158  0.309
2016 Volk N, Pape JC, Engel M, Zannas AS, Cattane N, Cattaneo A, Binder EB, Chen A. Amygdalar MicroRNA-15a Is Essential for Coping with Chronic Stress. Cell Reports. 17: 1882-1891. PMID 27829158 DOI: 10.1016/J.Celrep.2016.10.038  0.347
2016 Halldorsdottir T, Binder EB. Gene × Environment Interactions: From Molecular Mechanisms to Behavior. Annual Review of Psychology. PMID 27732803 DOI: 10.1146/annurev-psych-010416-044053  0.325
2016 Knight AK, Craig JM, Theda C, Bækvad-Hansen M, Bybjerg-Grauholm J, Hansen CS, Hollegaard MV, Hougaard DM, Mortensen PB, Weinsheimer SM, Werge TM, Brennan PA, Cubells JF, Newport DJ, Stowe ZN, ... ... Binder EB, et al. An epigenetic clock for gestational age at birth based on blood methylation data. Genome Biology. 17: 206. PMID 27717399 DOI: 10.1186/S13059-016-1068-Z  0.549
2016 Grünewald L, Landaas ET, Geissler J, Weber H, Quast C, Röh S, Schartner C, Lesch KP, Romanos M, Kittel-Schneider S, Binder E, Reif A. Functional Impact of an ADHD-Associated DIRAS2 Promoter Polymorphism. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 27364329 DOI: 10.1038/Npp.2016.113  0.311
2016 Gassen NC, Chrousos GP, Binder EB, Zannas AS. Life stress, glucocorticoid signaling, and the aging epigenome: implications for aging-related diseases. Neuroscience and Biobehavioral Reviews. PMID 27343999 DOI: 10.1016/j.neubiorev.2016.06.003  0.331
2016 Kilaru V, Iyer SV, Almli LM, Stevens JS, Lori A, Jovanovic T, Ely TD, Bradley B, Binder EB, Koen N, Stein DJ, Conneely KN, Wingo AP, Smith AK, Ressler KJ. Genome-wide gene-based analysis suggests an association between Neuroligin 1 (NLGN1) and post-traumatic stress disorder. Translational Psychiatry. 6: e820. PMID 27219346 DOI: 10.1038/Tp.2016.69  0.374
2016 Trost S, Diekhof EK, Mohr H, Vieker H, Krämer B, Wolf C, Keil M, Dechent P, Binder EB, Gruber O. Investigating the Impact of a Genome-Wide Supported Bipolar Risk Variant of MAD1L1 on the Human Reward System. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 27184339 DOI: 10.1038/Npp.2016.70  0.329
2016 Kimmel M, Clive M, Gispen F, Guintivano J, Brown T, Cox O, Beckmann MW, Kornhuber J, Fasching PA, Osborne LM, Binder E, Payne JL, Kaminsky Z. Oxytocin receptor DNA methylation in postpartum depression. Psychoneuroendocrinology. 69: 150-160. PMID 27108164 DOI: 10.1016/J.Psyneuen.2016.04.008  0.389
2016 Menke A, Arloth J, Best J, Namendorf C, Gerlach T, Czamara D, Lucae S, Dunlop BW, Crowe TM, Garlow SJ, Nemeroff CB, Ritchie JC, Craighead WE, Mayberg HS, Rex-Haffner M, ... Binder EB, et al. Time-dependent effects of dexamethasone plasma concentrations on glucocorticoid receptor challenge tests. Psychoneuroendocrinology. 69: 161-171. PMID 27107207 DOI: 10.1016/j.psyneuen.2016.04.003  0.594
2016 Houtepen LC, Vinkers CH, Carrillo-Roa T, Hiemstra M, van Lier PA, Meeus W, Branje S, Heim CM, Nemeroff CB, Mill J, Schalkwyk LC, Creyghton MP, Kahn RS, Joëls M, Binder EB, et al. Genome-wide DNA methylation levels and altered cortisol stress reactivity following childhood trauma in humans. Nature Communications. 7: 10967. PMID 26997371 DOI: 10.1038/Ncomms10967  0.618
2016 Wingo AP, Almli LM, Stevens JS, Klengel T, Uddin M, Li Y, Bustamante AC, Lori A, Koen N, Stein DJ, Smith AK, Aiello AE, Koenen KC, Wildman DE, Galea S, ... ... Binder EB, et al. Corrigendum: DICER1 and microRNA regulation in post-traumatic stress disorder with comorbid depression. Nature Communications. 7: 10958. PMID 26936533 DOI: 10.1038/Ncomms10958  0.314
2016 Kao CY, He Z, Zannas AS, Hahn O, Kühne C, Reichel JM, Binder EB, Wotjak CT, Khaitovich P, Turck CW. Fluoxetine treatment prevents the inflammatory response in a mouse model of posttraumatic stress disorder. Journal of Psychiatric Research. 76: 74-83. PMID 26897419 DOI: 10.1016/J.Jpsychires.2016.02.003  0.347
2016 Iyer S, Kilaru V, Almli L, Stevens J, Jovanovic T, Conneely K, Wingo A, Smith A, Ressler K, Lori A, Ely T, Bradley B, Binder E, Koen N, Stein D. Genome-wide gene-based analysis suggests an association between Neuroligin 1 (NLGN1) and Post-traumatic Stress Disorder F1000research. 5. DOI: 10.7490/F1000Research.1112140.1  0.358
2016 Pape JC, Binder EB. The Role of Genetics and Epigenetics in the Pathogenesis of Posttraumatic Stress Disorder Psychiatric Annals. 46: 510-518. DOI: 10.3928/00485713-20160729-02  0.343
2016 Carrillo-Roa T, Dunlop B, McGrath C, Czamara D, Zaanas A, Kelley M, Nemeroff C, Craighead W, Mayberg H, Binder E. P.3.004 Neuroimaging derived polygenic scores predict outcomes to psychotherapy and medication treatments for depression European Neuropsychopharmacology. 26: S48-S49. DOI: 10.1016/S0924-977X(16)70054-X  0.352
2016 Suarez A, Lahti JMT, Girchenko P, Lahti M, Hamalainen E, Laivuori H, Kajantie E, Pesonen A, Villa PM, Reynolds RM, Czamara D, Binder EB, Raikkonen K. Maternal depression during pregnancy and epigenetic age in their newborns: The PREDO study Psychoneuroendocrinology. 71: 63-63. DOI: 10.1016/J.Psyneuen.2016.07.163  0.303
2016 Smith A, Kilaru V, Klengel T, Nishitani S, Binder E, Ressler K, Bradley B, Jovanovic T. Heritable epigenetic patterns of stress-responsive genes in traumatized children Psychoneuroendocrinology. 71: 43-43. DOI: 10.1016/J.Psyneuen.2016.07.112  0.316
2016 Toepfer P, Heim CM, Entringer S, Wadhwa PD, Provencal N, Binder EB, Buss C. A variation in the oxytocin receptor gene moderates the relationship between early maternal care in childhood and interleukin 6 (IL-6) concentrations during pregnancy Psychoneuroendocrinology. 71: 15. DOI: 10.1016/J.Psyneuen.2016.07.049  0.482
2016 Jones I, Clive M, Wilcox H, Eaton W, Eck KV, Jovanovic T, Klengel T, Bradley B, Binder E, Geuze E, Rutten B, Houtepen L, Vermetten E, Vinkers C, Ressler K, et al. Stress vulnerability and epigenetic variation of SKA2, potential causes and consequences Psychoneuroendocrinology. 71: 11-11. DOI: 10.1016/J.Psyneuen.2016.07.038  0.314
2016 Jacoby N, Overfeld J, Binder EB, Heim CM. Stress Neurobiology and Developmental Psychopathology Development and Psychopathology. 1-45. DOI: 10.1002/9781119125556.Devpsy221  0.388
2015 Zannas AS, Arloth J, Carrillo-Roa T, Iurato S, Röh S, Ressler KJ, Nemeroff CB, Smith AK, Bradley B, Heim C, Menke A, Lange JF, Brückl T, Ising M, Wray NR, ... ... Binder EB, et al. Lifetime stress accelerates epigenetic aging in an urban, African American cohort: relevance of glucocorticoid signaling. Genome Biology. 16: 266. PMID 26673150 DOI: 10.1186/s13059-015-0828-5  0.589
2015 Wingo AP, Almli LM, Stevens JJ, Klengel T, Uddin M, Li Y, Bustamante AC, Lori A, Koen N, Stein DJ, Smith AK, Aiello AE, Koenen KC, Wildman DE, Galea S, ... ... Binder EB, et al. DICER1 and microRNA regulation in post-traumatic stress disorder with comorbid depression. Nature Communications. 6: 10106. PMID 26632874 DOI: 10.1038/Ncomms10106  0.34
2015 Gassen NC, Fries GR, Zannas AS, Hartmann J, Zschocke J, Hafner K, Carrillo-Roa T, Steinbacher J, Preißinger SN, Hoeijmakers L, Knop M, Weber F, Kloiber S, Lucae S, Chrousos GP, ... ... Binder EB, et al. Chaperoning epigenetics: FKBP51 decreases the activity of DNMT1 and mediates epigenetic effects of the antidepressant paroxetine. Science Signaling. 8: ra119. PMID 26602018 DOI: 10.1126/Scisignal.Aac7695  0.349
2015 Osborne L, Clive M, Kimmel M, Gispen F, Guintivano J, Brown T, Cox O, Judy J, Meilman S, Brier A, Beckmann MW, Kornhuber J, Fasching PA, Goes F, Payne JL, ... Binder EB, et al. Replication of Epigenetic Postpartum Depression Biomarkers and Variation with Hormone Levels. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 26503311 DOI: 10.1038/Npp.2015.333  0.361
2015 Yehuda R, Daskalakis NP, Bierer LM, Bader HN, Klengel T, Holsboer F, Binder EB. Holocaust Exposure Induced Intergenerational Effects on FKBP5 Methylation. Biological Psychiatry. PMID 26410355 DOI: 10.1016/J.Biopsych.2015.08.005  0.624
2015 Kaminsky Z, Wilcox HC, Eaton WW, Van Eck K, Kilaru V, Jovanovic T, Klengel T, Bradley B, Binder EB, Ressler KJ, Smith AK. Epigenetic and genetic variation at SKA2 predict suicidal behavior and post-traumatic stress disorder. Translational Psychiatry. 5: e627. PMID 26305478 DOI: 10.1038/Tp.2015.105  0.366
2015 Zannas AS, Wiechmann T, Gassen NC, Binder EB. Gene-Stress-Epigenetic Regulation of FKBP5: Clinical and Translational Implications. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 26250598 DOI: 10.1038/npp.2015.235  0.4
2015 Feng C, Lori A, Waldman ID, Binder EB, Haroon E, Rilling JK. A common oxytocin receptor gene (OXTR) polymorphism modulates intranasal oxytocin effects on the neural response to social cooperation in humans. Genes, Brain, and Behavior. 14: 516-25. PMID 26178189 DOI: 10.1111/Gbb.12234  0.318
2015 Kohrt BA, Worthman CM, Ressler KJ, Mercer KB, Upadhaya N, Koirala S, Nepal MK, Sharma VD, Binder EB. Cross-cultural gene- environment interactions in depression, post-traumatic stress disorder, and the cortisol awakening response: FKBP5 polymorphisms and childhood trauma in South Asia. International Review of Psychiatry (Abingdon, England). 27: 180-96. PMID 26100613 DOI: 10.3109/09540261.2015.1020052  0.408
2015 Klengel T, Binder EB. Epigenetics of Stress-Related Psychiatric Disorders and Gene × Environment Interactions. Neuron. 86: 1343-57. PMID 26087162 DOI: 10.1016/j.neuron.2015.05.036  0.389
2015 Arloth J, Bogdan R, Weber P, Frishman G, Menke A, Wagner KV, Balsevich G, Schmidt MV, Karbalai N, Czamara D, Altmann A, Trümbach D, Wurst W, Mehta D, Uhr M, ... ... Binder EB, et al. Genetic Differences in the Immediate Transcriptome Response to Stress Predict Risk-Related Brain Function and Psychiatric Disorders. Neuron. 86: 1189-202. PMID 26050039 DOI: 10.1016/J.Neuron.2015.05.034  0.416
2015 Zannas AS, Provençal N, Binder EB. Epigenetics of Posttraumatic Stress Disorder: Current Evidence, Challenges, and Future Directions. Biological Psychiatry. 78: 327-35. PMID 25979620 DOI: 10.1016/j.biopsych.2015.04.003  0.384
2015 Logue MW, Smith AK, Baldwin C, Wolf EJ, Guffanti G, Ratanatharathorn A, Stone A, Schichman SA, Humphries D, Binder EB, Arloth J, Menke A, Uddin M, Wildman D, Galea S, et al. An analysis of gene expression in PTSD implicates genes involved in the glucocorticoid receptor pathway and neural responses to stress. Psychoneuroendocrinology. 57: 1-13. PMID 25867994 DOI: 10.1016/J.Psyneuen.2015.03.016  0.352
2015 Daskalakis NP, Binder EB. Schizophrenia in the spectrum of gene-stress interactions: the FKBP5 example. Schizophrenia Bulletin. 41: 323-9. PMID 25592294 DOI: 10.1093/Schbul/Sbu189  0.633
2015 Klengel T, Binder EB. FKBP5 allele-specific epigenetic modification in gene by environment interaction. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 40: 244-6. PMID 25482174 DOI: 10.1038/npp.2014.208  0.408
2015 Gaali S, Kirschner A, Cuboni S, Hartmann J, Kozany C, Balsevich G, Namendorf C, Fernandez-Vizarra P, Sippel C, Zannas AS, Draenert R, Binder EB, Almeida OF, Rühter G, Uhr M, et al. Selective inhibitors of the FK506-binding protein 51 by induced fit. Nature Chemical Biology. 11: 33-7. PMID 25436518 DOI: 10.1038/Nchembio.1699  0.317
2015 Smith AK, Kilaru V, Klengel T, Mercer KB, Bradley B, Conneely KN, Ressler KJ, Binder EB. DNA extracted from saliva for methylation studies of psychiatric traits: evidence tissue specificity and relatedness to brain. American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics. 168: 36-44. PMID 25355443 DOI: 10.1002/Ajmg.B.32278  0.304
2015 Jukic MM, Carrillo-Roa T, Bar M, Becker G, Jovanovic VM, Zega K, Binder EB, Brodski C. Abnormal development of monoaminergic neurons is implicated in mood fluctuations and bipolar disorder. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 40: 839-48. PMID 25241801 DOI: 10.1038/npp.2014.244  0.317
2015 Provencal N, Binder EB. The neurobiological effects of stress as contributors to psychiatric disorders: focus on epigenetics. Current Opinion in Neurobiology. 30: 31-7. PMID 25218938 DOI: 10.1016/j.conb.2014.08.007  0.351
2015 Provençal N, Binder EB. The effects of early life stress on the epigenome: From the womb to adulthood and even before. Experimental Neurology. 268: 10-20. PMID 25218020 DOI: 10.1016/j.expneurol.2014.09.001  0.36
2015 Zannas A, Carrillo-Roa T, Iurato S, Ressler K, Nemeroff C, Smith A, Lange J, Bradley B, Heim C, Brückl T, Ising M, Wray N, Erhardt A, Binder E, Mehta D. Lifetime Stress Accelerates Epigenetic Aging European Psychiatry. 30: 799. DOI: 10.1016/S0924-9338(15)31949-0  0.62
2014 Rampp C, Binder EB, Provençal N. Epigenetics in posttraumatic stress disorder. Progress in Molecular Biology and Translational Science. 128: 29-50. PMID 25410540 DOI: 10.1016/B978-0-12-800977-2.00002-4  0.384
2014 Almli LM, Duncan R, Feng H, Ghosh D, Binder EB, Bradley B, Ressler KJ, Conneely KN, Epstein MP. Correcting systematic inflation in genetic association tests that consider interaction effects: application to a genome-wide association study of posttraumatic stress disorder. Jama Psychiatry. 71: 1392-9. PMID 25354142 DOI: 10.1001/Jamapsychiatry.2014.1339  0.368
2014 Pape JC, Binder EB. [Psychological trauma as risk for delayed psychiatric disorders: epigenetic mechanisms]. Der Nervenarzt. 85: 1382-9. PMID 25208492 DOI: 10.1007/s00115-014-4085-8  0.334
2014 Sabbagh JJ, O'Leary JC, Blair LJ, Klengel T, Nordhues BA, Fontaine SN, Binder EB, Dickey CA. Age-associated epigenetic upregulation of the FKBP5 gene selectively impairs stress resiliency. Plos One. 9: e107241. PMID 25191701 DOI: 10.1371/journal.pone.0107241  0.394
2014 Mullins N, Perroud N, Uher R, Butler AW, Cohen-Woods S, Rivera M, Malki K, Euesden J, Power RA, Tansey KE, Jones L, Jones I, Craddock N, Owen MJ, Korszun A, ... ... Binder EB, et al. Genetic relationships between suicide attempts, suicidal ideation and major psychiatric disorders: a genome-wide association and polygenic scoring study. American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics. 165: 428-37. PMID 24964207 DOI: 10.1002/Ajmg.B.32247  0.35
2014 Issler O, Haramati S, Paul ED, Maeno H, Navon I, Zwang R, Gil S, Mayberg HS, Dunlop BW, Menke A, Awatramani R, Binder EB, Deneris ES, Lowry CA, Chen A. MicroRNA 135 is essential for chronic stress resiliency, antidepressant efficacy, and intact serotonergic activity. Neuron. 83: 344-60. PMID 24952960 DOI: 10.1016/J.Neuron.2014.05.042  0.327
2014 Dunlop BW, Rothbaum BO, Binder EB, Duncan E, Harvey PD, Jovanovic T, Kelley ME, Kinkead B, Kutner M, Iosifescu DV, Mathew SJ, Neylan TC, Kilts CD, Nemeroff CB, Mayberg HS. Evaluation of a corticotropin releasing hormone type 1 receptor antagonist in women with posttraumatic stress disorder: study protocol for a randomized controlled trial. Trials. 15: 240. PMID 24950747 DOI: 10.1186/1745-6215-15-240  0.699
2014 Labermaier C, Kohl C, Hartmann J, Devigny C, Altmann A, Weber P, Arloth J, Quast C, Wagner KV, Scharf SH, Czibere L, Widner-Andrä R, Brenndörfer J, Landgraf R, Hausch F, ... ... Binder EB, et al. A polymorphism in the Crhr1 gene determines stress vulnerability in male mice. Endocrinology. 155: 2500-10. PMID 24773341 DOI: 10.1210/En.2013-1986  0.388
2014 Menke A, Arloth J, Gerber M, Rex-Haffner M, Uhr M, Holsboer F, Binder EB, Holsboer-Trachsler E, Beck J. Dexamethasone stimulated gene expression in peripheral blood indicates glucocorticoid-receptor hypersensitivity in job-related exhaustion. Psychoneuroendocrinology. 44: 35-46. PMID 24767618 DOI: 10.1055/S-0033-1353309  0.322
2014 Schneider M, Engel A, Fasching PA, Häberle L, Binder EB, Voigt F, Grimm J, Faschingbauer F, Eichler A, Dammer U, Rebhan D, Amann M, Raabe E, Goecke TW, Quast C, et al. Genetic variants in the genes of the stress hormone signalling pathway and depressive symptoms during and after pregnancy. Biomed Research International. 2014: 469278. PMID 24741566 DOI: 10.1155/2014/469278  0.376
2014 Nemeroff CB, Binder E. The preeminent role of childhood abuse and neglect in vulnerability to major psychiatric disorders: toward elucidating the underlying neurobiological mechanisms. Journal of the American Academy of Child and Adolescent Psychiatry. 53: 395-7. PMID 24655648 DOI: 10.1016/j.jaac.2014.02.004  0.47
2014 Mehta D, Newport DJ, Frishman G, Kraus L, Rex-Haffner M, Ritchie JC, Lori A, Knight BT, Stagnaro E, Ruepp A, Stowe ZN, Binder EB. Early predictive biomarkers for postpartum depression point to a role for estrogen receptor signaling. Psychological Medicine. 44: 2309-22. PMID 24495551 DOI: 10.1017/S0033291713003231  0.672
2014 Klengel T, Pape J, Binder EB, Mehta D. The role of DNA methylation in stress-related psychiatric disorders. Neuropharmacology. 80: 115-32. PMID 24452011 DOI: 10.1016/j.neuropharm.2014.01.013  0.397
2014 Thompson PM, Stein JL, Medland SE, Hibar DP, Vasquez AA, Renteria ME, Toro R, Jahanshad N, Schumann G, Franke B, Wright MJ, Martin NG, Agartz I, Alda M, Alhusaini S, ... ... Binder EB, et al. The ENIGMA Consortium: large-scale collaborative analyses of neuroimaging and genetic data. Brain Imaging and Behavior. 8: 153-82. PMID 24399358 DOI: 10.1007/S11682-013-9269-5  0.308
2014 Fani N, King TZ, Reiser E, Binder EB, Jovanovic T, Bradley B, Ressler KJ. FKBP5 genotype and structural integrity of the posterior cingulum. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 39: 1206-13. PMID 24253961 DOI: 10.1038/Npp.2013.322  0.38
2014 Zannas AS, Binder EB. Gene-environment interactions at the FKBP5 locus: sensitive periods, mechanisms and pleiotropism. Genes, Brain, and Behavior. 13: 25-37. PMID 24219237 DOI: 10.1111/gbb.12104  0.373
2014 Ferentinos P, Rivera M, Ising M, Spain SL, Cohen-Woods S, Butler AW, Craddock N, Owen MJ, Korszun A, Jones L, Jones I, Gill M, Rice JP, Maier W, Mors O, ... ... Binder EB, et al. Investigating the genetic variation underlying episodicity in major depressive disorder: suggestive evidence for a bipolar contribution. Journal of Affective Disorders. 155: 81-9. PMID 24215895 DOI: 10.1016/J.Jad.2013.10.027  0.356
2014 Zannas A, Klengel T, Nemeroff C, Carrillo-Roa T, Heim C, Bradley B, Ressler K, Binder E. P.1.a.003 Epigenetic regulation at the FKBP5 genetic locus by age and depressive phenotypes: implications for age-related disease European Neuropsychopharmacology. 24: S154. DOI: 10.1016/S0924-977X(14)70234-2  0.367
2013 Lee SH, Ripke S, Neale BM, Faraone SV, Purcell SM, Perlis RH, Mowry BJ, Thapar A, Goddard ME, Witte JS, Absher D, Agartz I, Akil H, Amin F, ... ... Binder EB, et al. Genetic relationship between five psychiatric disorders estimated from genome-wide SNPs. Nature Genetics. 45: 984-94. PMID 23933821 DOI: 10.1038/Ng.2711  0.32
2013 Quast C, Cuboni S, Bader D, Altmann A, Weber P, Arloth J, Röh S, Brückl T, Ising M, Kopczak A, Erhardt A, Hausch F, Lucae S, Binder EB. Functional coding variants in SLC6A15, a possible risk gene for major depression. Plos One. 8: e68645. PMID 23874702 DOI: 10.1371/Journal.Pone.0068645  0.358
2013 Andero R, Brothers SP, Jovanovic T, Chen YT, Salah-Uddin H, Cameron M, Bannister TD, Almli L, Stevens JS, Bradley B, Binder EB, Wahlestedt C, Ressler KJ. Amygdala-dependent fear is regulated by Oprl1 in mice and humans with PTSD. Science Translational Medicine. 5: 188ra73. PMID 23740899 DOI: 10.1126/Scitranslmed.3005656  0.333
2013 Mehta D, Klengel T, Conneely KN, Smith AK, Altmann A, Pace TW, Rex-Haffner M, Loeschner A, Gonik M, Mercer KB, Bradley B, Müller-Myhsok B, Ressler KJ, Binder EB. Childhood maltreatment is associated with distinct genomic and epigenetic profiles in posttraumatic stress disorder. Proceedings of the National Academy of Sciences of the United States of America. 110: 8302-7. PMID 23630272 DOI: 10.1073/Pnas.1217750110  0.392
2013 Mehta D, Raison CL, Woolwine BJ, Haroon E, Binder EB, Miller AH, Felger JC. Transcriptional signatures related to glucose and lipid metabolism predict treatment response to the tumor necrosis factor antagonist infliximab in patients with treatment-resistant depression. Brain, Behavior, and Immunity. 31: 205-15. PMID 23624296 DOI: 10.1016/j.bbi.2013.04.004  0.321
2013 Norrholm SD, Jovanovic T, Smith AK, Binder E, Klengel T, Conneely K, Mercer KB, Davis JS, Kerley K, Winkler J, Gillespie CF, Bradley B, Ressler KJ. Differential Genetic and Epigenetic Regulation of catechol-O-methyltransferase is Associated with Impaired Fear Inhibition in Posttraumatic Stress Disorder. Frontiers in Behavioral Neuroscience. 7: 30. PMID 23596403 DOI: 10.3389/Fnbeh.2013.00030  0.657
2013 Klengel T, Binder EB. Allele-specific epigenetic modification: a molecular mechanism for gene-environment interactions in stress-related psychiatric disorders? Epigenomics. 5: 109-12. PMID 23566086 DOI: 10.2217/epi.13.11  0.422
2013 Gillespie CF, Almli LM, Smith AK, Bradley B, Kerley K, Crain DF, Mercer KB, Weiss T, Phifer J, Tang Y, Cubells JF, Binder EB, Conneely KN, Ressler KJ. Sex dependent influence of a functional polymorphism in steroid 5-α-reductase type 2 (SRD5A2) on post-traumatic stress symptoms. American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics. 162: 283-92. PMID 23505265 DOI: 10.1002/Ajmg.B.32147  0.656
2013 Klengel T, Binder EB. Gene-environment interactions in major depressive disorder. Canadian Journal of Psychiatry. Revue Canadienne De Psychiatrie. 58: 76-83. PMID 23442893 DOI: 10.1177/070674371305800203  0.396
2013 Fani N, Gutman D, Tone EB, Almli L, Mercer KB, Davis J, Glover E, Jovanovic T, Bradley B, Dinov ID, Zamanyan A, Toga AW, Binder EB, Ressler KJ. FKBP5 and attention bias for threat: associations with hippocampal function and shape. Jama Psychiatry. 70: 392-400. PMID 23407841 DOI: 10.1001/2013.Jamapsychiatry.210  0.576
2013 Menke A, Klengel T, Rubel J, Brückl T, Pfister H, Lucae S, Uhr M, Holsboer F, Binder EB. Genetic variation in FKBP5 associated with the extent of stress hormone dysregulation in major depression. Genes, Brain, and Behavior. 12: 289-96. PMID 23406438 DOI: 10.1111/Gbb.12026  0.389
2013 Power RA, Wingenbach T, Cohen-Woods S, Uher R, Ng MY, Butler AW, Ising M, Craddock N, Owen MJ, Korszun A, Jones L, Jones I, Gill M, Rice JP, Maier W, ... ... Binder EB, et al. Estimating the heritability of reporting stressful life events captured by common genetic variants. Psychological Medicine. 43: 1965-71. PMID 23237013 DOI: 10.1017/S0033291712002589  0.319
2013 Klengel T, Binder EB. Gene × environment interactions in the prediction of response to antidepressant treatment. The International Journal of Neuropsychopharmacology / Official Scientific Journal of the Collegium Internationale Neuropsychopharmacologicum (Cinp). 16: 701-11. PMID 23237009 DOI: 10.1017/S1461145712001459  0.366
2013 Klengel T, Mehta D, Anacker C, Rex-Haffner M, Pruessner JC, Pariante CM, Pace TW, Mercer KB, Mayberg HS, Bradley B, Nemeroff CB, Holsboer F, Heim CM, Ressler KJ, Rein T, ... Binder EB, et al. Allele-specific FKBP5 DNA demethylation mediates gene-childhood trauma interactions. Nature Neuroscience. 16: 33-41. PMID 23201972 DOI: 10.1038/Nn.3275  0.646
2013 Kloiber S, Ripke S, Kohli MA, Reppermund S, Salyakina D, Uher R, McGuffin P, Perlis RH, Hamilton SP, Pütz B, Hennings J, Brückl T, Klengel T, Bettecken T, Ising M, ... ... Binder E, et al. Resistance to antidepressant treatment is associated with polymorphisms in the leptin gene, decreased leptin mRNA expression, and decreased leptin serum levels. European Neuropsychopharmacology : the Journal of the European College of Neuropsychopharmacology. 23: 653-62. PMID 23026132 DOI: 10.1016/J.Euroneuro.2012.08.010  0.364
2013 Bourke CH, Raees MQ, Malviya S, Bradburn CA, Binder EB, Neigh GN. Glucocorticoid sensitizers Bag1 and Ppid are regulated by adolescent stress in a sex-dependent manner. Psychoneuroendocrinology. 38: 84-93. PMID 22647578 DOI: 10.1016/j.psyneuen.2012.05.001  0.708
2012 Power RA, Keers R, Ng MY, Butler AW, Uher R, Cohen-Woods S, Ising M, Craddock N, Owen MJ, Korszun A, Jones L, Jones I, Gill M, Rice JP, Hauser J, ... ... Binder EB, et al. Dissecting the genetic heterogeneity of depression through age at onset. American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics. 159: 859-68. PMID 22915352 DOI: 10.1002/Ajmg.B.32093  0.345
2012 Kennedy AP, Binder EB, Bowman D, Harenski K, Ely T, Cisler JM, Tripathi SP, VanNess S, Kilts CD. A common TPH2 haplotype regulates the neural processing of a cognitive control demand. American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics. 159: 829-40. PMID 22915309 DOI: 10.1002/Ajmg.B.32090  0.32
2012 Quast C, Altmann A, Weber P, Arloth J, Bader D, Heck A, Pfister H, Müller-Myhsok B, Erhardt A, Binder EB. Rare variants in TMEM132D in a case-control sample for panic disorder. American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics. 159: 896-907. PMID 22911938 DOI: 10.1002/ajmg.b.32096  0.324
2012 Dunlop BW, Binder EB, Cubells JF, Goodman MM, Kelley ME, Kinkead B, Kutner M, Nemeroff CB, Newport DJ, Owens MJ, Pace TW, Ritchie JC, Rivera VA, Westen D, Craighead WE, et al. Predictors of remission in depression to individual and combined treatments (PReDICT): study protocol for a randomized controlled trial. Trials. 13: 106. PMID 22776534 DOI: 10.1186/1745-6215-13-106  0.761
2012 Fasching PA, Faschingbauer F, Goecke TW, Engel A, Häberle L, Seifert A, Voigt F, Amann M, Rebhan D, Burger P, Kornhuber J, Ekici AB, Beckmann MW, Binder EB. Genetic variants in the tryptophan hydroxylase 2 gene (TPH2) and depression during and after pregnancy. Journal of Psychiatric Research. 46: 1109-17. PMID 22721547 DOI: 10.1016/J.Jpsychires.2012.05.011  0.35
2012 Menke A, Klengel T, Binder EB. Epigenetics, depression and antidepressant treatment. Current Pharmaceutical Design. 18: 5879-89. PMID 22681167 DOI: 10.2174/138161212803523590  0.387
2012 Hunter JE, Leslie M, Novak G, Hamilton D, Shubeck L, Charen K, Abramowitz A, Epstein MP, Lori A, Binder E, Cubells JF, Sherman SL. Depression and anxiety symptoms among women who carry the FMR1 premutation: impact of raising a child with fragile X syndrome is moderated by CRHR1 polymorphisms. American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics. 159: 549-59. PMID 22573456 DOI: 10.1002/ajmg.b.32061  0.38
2012 Stein JL, Medland SE, Vasquez AA, Hibar DP, Senstad RE, Winkler AM, Toro R, Appel K, Bartecek R, Bergmann Ø, Bernard M, Brown AA, Cannon DM, Chakravarty MM, Christoforou A, ... ... Binder EB, et al. Identification of common variants associated with human hippocampal and intracranial volumes. Nature Genetics. 44: 552-61. PMID 22504417 DOI: 10.1038/Ng.2250  0.306
2012 Binder EB, Holsboer F. Low cortisol and risk and resilience to stress-related psychiatric disorders. Biological Psychiatry. 71: 282-3. PMID 22265026 DOI: 10.1016/J.Biopsych.2011.12.008  0.334
2012 Menke A, Arloth J, Pütz B, Weber P, Klengel T, Mehta D, Gonik M, Rex-Haffner M, Rubel J, Uhr M, Lucae S, Deussing JM, Müller-Myhsok B, Holsboer F, Binder EB. Dexamethasone stimulated gene expression in peripheral blood is a sensitive marker for glucocorticoid receptor resistance in depressed patients. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 37: 1455-64. PMID 22237309 DOI: 10.1038/Npp.2011.331  0.351
2012 Mehta D, Quast C, Fasching PA, Seifert A, Voigt F, Beckmann MW, Faschingbauer F, Burger P, Ekici AB, Kornhuber J, Binder EB, Goecke TW. The 5-HTTLPR polymorphism modulates the influence on environmental stressors on peripartum depression symptoms. Journal of Affective Disorders. 136: 1192-7. PMID 22209125 DOI: 10.1016/J.Jad.2011.11.042  0.374
2012 Cáceda R, Binder EB, Kinkead B, Nemeroff CB. The role of endogenous neurotensin in psychostimulant-induced disruption of prepulse inhibition and locomotion. Schizophrenia Research. 136: 88-95. PMID 22104138 DOI: 10.1016/j.schres.2011.10.013  0.761
2012 Heim C, Binder EB. Current research trends in early life stress and depression: review of human studies on sensitive periods, gene-environment interactions, and epigenetics. Experimental Neurology. 233: 102-11. PMID 22101006 DOI: 10.1016/j.expneurol.2011.10.032  0.56
2012 Menke A, Domschke K, Czamara D, Klengel T, Hennings J, Lucae S, Baune BT, Arolt V, Müller-Myhsok B, Holsboer F, Binder EB. Genome-wide association study of antidepressant treatment-emergent suicidal ideation. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 37: 797-807. PMID 22030708 DOI: 10.1038/Npp.2011.257  0.329
2012 Katz ER, Stowe ZN, Newport DJ, Kelley ME, Pace TW, Cubells JF, Binder EB. Regulation of mRNA expression encoding chaperone and co-chaperone proteins of the glucocorticoid receptor in peripheral blood: association with depressive symptoms during pregnancy. Psychological Medicine. 42: 943-56. PMID 21995950 DOI: 10.1017/S0033291711002121  0.678
2012 Menke A, Sämann P, Kloiber S, Czamara D, Lucae S, Hennings J, Heck A, Kohli MA, Czisch M, Müller-Myhsok B, Holsboer F, Binder EB. Polymorphisms within the metabotropic glutamate receptor 1 gene are associated with depression phenotypes. Psychoneuroendocrinology. 37: 565-75. PMID 21962378 DOI: 10.1016/J.Psyneuen.2011.09.003  0.384
2012 Mehta D, Binder EB. Gene × environment vulnerability factors for PTSD: the HPA-axis. Neuropharmacology. 62: 654-62. PMID 21439305 DOI: 10.1016/j.neuropharm.2011.03.009  0.342
2011 Klengel T, Binder EB. Using gene-environment interactions to target personalized treatment in mood disorder. Personalized Medicine. 8: 23-34. PMID 29768787 DOI: 10.2217/pme.10.73  0.371
2011 Bradley B, Westen D, Mercer KB, Binder EB, Jovanovic T, Crain D, Wingo A, Heim C. Association between childhood maltreatment and adult emotional dysregulation in a low-income, urban, African American sample: moderation by oxytocin receptor gene. Development and Psychopathology. 23: 439-52. PMID 23786688 DOI: 10.1017/S0954579411000162  0.522
2011 Zimmermann P, Brückl T, Nocon A, Pfister H, Binder EB, Uhr M, Lieb R, Moffitt TE, Caspi A, Holsboer F, Ising M. Interaction of FKBP5 gene variants and adverse life events in predicting depression onset: results from a 10-year prospective community study. The American Journal of Psychiatry. 168: 1107-16. PMID 21865530 DOI: 10.1176/Appi.Ajp.2011.10111577  0.41
2011 Schosser A, Butler AW, Ising M, Perroud N, Uher R, Ng MY, Cohen-Woods S, Craddock N, Owen MJ, Korszun A, Jones L, Jones I, Gill M, Rice JP, Maier W, ... ... Binder EB, et al. Genomewide association scan of suicidal thoughts and behaviour in major depression. Plos One. 6: e20690. PMID 21750702 DOI: 10.1371/Journal.Pone.0020690  0.343
2011 Horstmann S, Binder EB. Glucocorticoids as predictors of treatment response in depression. Harvard Review of Psychiatry. 19: 125-43. PMID 21631159 DOI: 10.3109/10673229.2011.586550  0.381
2011 Mehta D, Gonik M, Klengel T, Rex-Haffner M, Menke A, Rubel J, Mercer KB, Pütz B, Bradley B, Holsboer F, Ressler KJ, Müller-Myhsok B, Binder EB. Using polymorphisms in FKBP5 to define biologically distinct subtypes of posttraumatic stress disorder: evidence from endocrine and gene expression studies. Archives of General Psychiatry. 68: 901-10. PMID 21536970 DOI: 10.1001/Archgenpsychiatry.2011.50  0.393
2011 Kohli MA, Lucae S, Saemann PG, Schmidt MV, Demirkan A, Hek K, Czamara D, Alexander M, Salyakina D, Ripke S, Hoehn D, Specht M, Menke A, Hennings J, Heck A, ... ... Binder EB, et al. The neuronal transporter gene SLC6A15 confers risk to major depression. Neuron. 70: 252-65. PMID 21521612 DOI: 10.1016/J.Neuron.2011.04.005  0.364
2011 Ressler KJ, Mercer KB, Bradley B, Jovanovic T, Mahan A, Kerley K, Norrholm SD, Kilaru V, Smith AK, Myers AJ, Ramirez M, Engel A, Hammack SE, Toufexis D, Braas KM, ... Binder EB, et al. Post-traumatic stress disorder is associated with PACAP and the PAC1 receptor. Nature. 470: 492-7. PMID 21350482 DOI: 10.1038/Nature09856  0.391
2011 Scharf SH, Liebl C, Binder EB, Schmidt MV, Müller MB. Expression and regulation of the Fkbp5 gene in the adult mouse brain. Plos One. 6: e16883. PMID 21347384 DOI: 10.1371/Journal.Pone.0016883  0.33
2011 Domschke K, Reif A, Weber H, Richter J, Hohoff C, Ohrmann P, Pedersen A, Bauer J, Suslow T, Kugel H, Heindel W, Baumann C, Klauke B, Jacob C, Maier W, ... ... Binder EB, et al. Neuropeptide S receptor gene -- converging evidence for a role in panic disorder. Molecular Psychiatry. 16: 938-48. PMID 20603625 DOI: 10.1038/Mp.2010.81  0.337
2011 Dunlop BW, Betancourt Y, Binder EB, Heim C, Holsboer F, Ising M, McKenzie M, Mletzko T, Pfister H, Nemeroff CB, Craighead WE, Mayberg HS. Tolerability of the dexamethasone-corticotropin releasing hormone test in major depressive disorder. Journal of Psychiatric Research. 45: 24-8. PMID 20488460 DOI: 10.1016/J.Jpsychires.2010.04.020  0.594
2011 Gillespie CF, Binder EB, Holtzheimer PE, Nemeroff CB. Stress and the Impact of Personalized Medicine Integrative Neuroscience and Personalized Medicine. DOI: 10.1093/acprof:oso/9780195393804.003.0005  0.628
2011 Pace T, Heim C, Binder E, Nemeroff C, Miller A. 159. History of childhood trauma is associated with impaired glucocorticoid sensitivity in adulthood Brain, Behavior, and Immunity. 25: S225. DOI: 10.1016/j.bbi.2011.07.162  0.434
2011 Binder E, Mehta D, Ressler K, Holsboer F. Posttraumatic stress disorder subtypes invalid - Reply Archives of General Psychiatry. 68: 978-980. DOI: 10.1001/Archgenpsychiatry.2011.94  0.325
2010 Schmidt MV, Trümbach D, Weber P, Wagner K, Scharf SH, Liebl C, Datson N, Namendorf C, Gerlach T, Kühne C, Uhr M, Deussing JM, Wurst W, Binder EB, Holsboer F, et al. Individual stress vulnerability is predicted by short-term memory and AMPA receptor subunit ratio in the hippocampus. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 30: 16949-58. PMID 21159965 DOI: 10.1523/Jneurosci.4668-10.2010  0.379
2010 Martin EI, Ressler KJ, Binder E, Nemeroff CB. The neurobiology of anxiety disorders: brain imaging, genetics, and psychoneuroendocrinology. Clinics in Laboratory Medicine. 30: 865-91. PMID 20832657 DOI: 10.1016/j.cll.2010.07.006  0.47
2010 Rietschel M, Mattheisen M, Frank J, Treutlein J, Degenhardt F, Breuer R, Steffens M, Mier D, Esslinger C, Walter H, Kirsch P, Erk S, Schnell K, Herms S, Wichmann HE, ... ... Binder EB, et al. Genome-wide association-, replication-, and neuroimaging study implicates HOMER1 in the etiology of major depression. Biological Psychiatry. 68: 578-85. PMID 20673876 DOI: 10.1016/j.biopsych.2010.05.038  0.369
2010 Mehta D, Menke A, Binder EB. Gene expression studies in major depression. Current Psychiatry Reports. 12: 135-44. PMID 20425299 DOI: 10.1007/s11920-010-0100-3  0.322
2010 Binder EB, Owens MJ, Liu W, Deveau TC, Rush AJ, Trivedi MH, Fava M, Bradley B, Ressler KJ, Nemeroff CB. Association of polymorphisms in genes regulating the corticotropin-releasing factor system with antidepressant treatment response. Archives of General Psychiatry. 67: 369-79. PMID 20368512 DOI: 10.1001/Archgenpsychiatry.2010.18  0.645
2010 Unschuld PG, Ising M, Roeske D, Erhardt A, Specht M, Kloiber S, Uhr M, Müller-Myhsok B, Holsboer F, Binder EB. Gender-specific association of galanin polymorphisms with HPA-axis dysregulation, symptom severity, and antidepressant treatment response. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 35: 1583-92. PMID 20237460 DOI: 10.1038/Npp.2010.30  0.411
2010 Kohli MA, Salyakina D, Pfennig A, Lucae S, Horstmann S, Menke A, Kloiber S, Hennings J, Bradley BB, Ressler KJ, Uhr M, Müller-Myhsok B, Holsboer F, Binder EB. Association of genetic variants in the neurotrophic receptor-encoding gene NTRK2 and a lifetime history of suicide attempts in depressed patients. Archives of General Psychiatry. 67: 348-59. PMID 20124106 DOI: 10.1001/Archgenpsychiatry.2009.201  0.379
2010 Binder EB, Newport DJ, Zach EB, Smith AK, Deveau TC, Altshuler LL, Cohen LS, Stowe ZN, Cubells JF. A serotonin transporter gene polymorphism predicts peripartum depressive symptoms in an at-risk psychiatric cohort. Journal of Psychiatric Research. 44: 640-6. PMID 20045118 DOI: 10.1016/j.jpsychires.2009.12.001  0.619
2010 Ressler KJ, Bradley B, Mercer KB, Deveau TC, Smith AK, Gillespie CF, Nemeroff CB, Cubells JF, Binder EB. Polymorphisms in CRHR1 and the serotonin transporter loci: gene x gene x environment interactions on depressive symptoms. American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics. 153: 812-24. PMID 20029939 DOI: 10.1002/Ajmg.B.31052  0.693
2010 Binder EB, Nemeroff CB. The CRF system, stress, depression and anxiety-insights from human genetic studies. Molecular Psychiatry. 15: 574-88. PMID 20010888 DOI: 10.1038/mp.2009.141  0.538
2010 Horstmann S, Lucae S, Menke A, Hennings JM, Ising M, Roeske D, Müller-Myhsok B, Holsboer F, Binder EB. Polymorphisms in GRIK4, HTR2A, and FKBP5 show interactive effects in predicting remission to antidepressant treatment. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 35: 727-40. PMID 19924111 DOI: 10.1038/Npp.2009.180  0.327
2010 Kloiber S, Kohli MA, Brueckl T, Ripke S, Ising M, Uhr M, Menke A, Unschuld PG, Horstmann S, Salyakina D, Muller-Myhsok B, Binder EB, Holsboer F, Lucae S. Variations in tryptophan hydroxylase 2 linked to decreased serotonergic activity are associated with elevated risk for metabolic syndrome in depression. Molecular Psychiatry. 15: 736-47. PMID 19125159 DOI: 10.1038/Mp.2008.142  0.378
2009 Heim C, Bradley B, Mletzko TC, Deveau TC, Musselman DL, Nemeroff CB, Ressler KJ, Binder EB. Effect of Childhood Trauma on Adult Depression and Neuroendocrine Function: Sex-Specific Moderation by CRH Receptor 1 Gene. Frontiers in Behavioral Neuroscience. 3: 41. PMID 20161813 DOI: 10.3389/neuro.08.041.2009  0.744
2009 Ising M, Lucae S, Binder EB, Bettecken T, Uhr M, Ripke S, Kohli MA, Hennings JM, Horstmann S, Kloiber S, Menke A, Bondy B, Rupprecht R, Domschke K, Baune BT, et al. A genomewide association study points to multiple loci that predict antidepressant drug treatment outcome in depression. Archives of General Psychiatry. 66: 966-75. PMID 19736353 DOI: 10.1001/Archgenpsychiatry.2009.95  0.348
2009 Martin EI, Ressler KJ, Binder E, Nemeroff CB. The neurobiology of anxiety disorders: brain imaging, genetics, and psychoneuroendocrinology. The Psychiatric Clinics of North America. 32: 549-75. PMID 19716990 DOI: 10.1016/j.psc.2009.05.004  0.47
2009 Horstmann S, Binder EB. Pharmacogenomics of antidepressant drugs. Pharmacology & Therapeutics. 124: 57-73. PMID 19563827 DOI: 10.1016/j.pharmthera.2009.06.007  0.356
2009 Binder EB. The role of FKBP5, a co-chaperone of the glucocorticoid receptor in the pathogenesis and therapy of affective and anxiety disorders. Psychoneuroendocrinology. 34: S186-95. PMID 19560279 DOI: 10.1016/j.psyneuen.2009.05.021  0.402
2009 Unschuld PG, Ising M, Specht M, Erhardt A, Ripke S, Heck A, Kloiber S, Straub V, Brueckl T, Müller-Myhsok B, Holsboer F, Binder EB. Polymorphisms in the GAD2 gene-region are associated with susceptibility for unipolar depression and with a risk factor for anxiety disorders. American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics. 150: 1100-9. PMID 19229853 DOI: 10.1002/Ajmg.B.30938  0.366
2009 Hennings JM, Owashi T, Binder EB, Horstmann S, Menke A, Kloiber S, Dose T, Wollweber B, Spieler D, Messer T, Lutz R, Künzel H, Bierner T, Pollmächer T, Pfister H, et al. Clinical characteristics and treatment outcome in a representative sample of depressed inpatients - findings from the Munich Antidepressant Response Signature (MARS) project. Journal of Psychiatric Research. 43: 215-29. PMID 18586274 DOI: 10.1016/J.Jpsychires.2008.05.002  0.338
2008 Keck ME, Kern N, Erhardt A, Unschuld PG, Ising M, Salyakina D, Müller MB, Knorr CC, Lieb R, Hohoff C, Krakowitzky P, Maier W, Bandelow B, Fritze J, Deckert J, ... ... Binder EB, et al. Combined effects of exonic polymorphisms in CRHR1 and AVPR1B genes in a case/control study for panic disorder. American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics. 147: 1196-204. PMID 18384079 DOI: 10.1002/Ajmg.B.30750  0.338
2008 Binder EB, Bradley RG, Liu W, Epstein MP, Deveau TC, Mercer KB, Tang Y, Gillespie CF, Heim CM, Nemeroff CB, Schwartz AC, Cubells JF, Ressler KJ. Association of FKBP5 polymorphisms and childhood abuse with risk of posttraumatic stress disorder symptoms in adults. Jama. 299: 1291-305. PMID 18349090 DOI: 10.1001/Jama.299.11.1291  0.743
2008 Bradley RG, Binder EB, Epstein MP, Tang Y, Nair HP, Liu W, Gillespie CF, Berg T, Evces M, Newport DJ, Stowe ZN, Heim CM, Nemeroff CB, Schwartz A, Cubells JF, et al. Influence of child abuse on adult depression: moderation by the corticotropin-releasing hormone receptor gene. Archives of General Psychiatry. 65: 190-200. PMID 18250257 DOI: 10.1001/Archgenpsychiatry.2007.26  0.798
2008 Uhr M, Tontsch A, Namendorf C, Ripke S, Lucae S, Ising M, Dose T, Ebinger M, Rosenhagen M, Kohli M, Kloiber S, Salyakina D, Bettecken T, Specht M, Pütz B, ... Binder EB, et al. Polymorphisms in the drug transporter gene ABCB1 predict antidepressant treatment response in depression. Neuron. 57: 203-9. PMID 18215618 DOI: 10.1016/J.Neuron.2007.11.017  0.333
2008 Unschuld PG, Ising M, Erhardt A, Lucae S, Kohli M, Kloiber S, Salyakina D, Thoeringer CK, Kern N, Lieb R, Uhr M, Binder EB, Müller-Myhsok B, Holsboer F, Keck ME. Polymorphisms in the galanin gene are associated with symptom-severity in female patients suffering from panic disorder. Journal of Affective Disorders. 105: 177-84. PMID 17573119 DOI: 10.1016/J.Jad.2007.05.006  0.382
2007 Himmerich H, Zimmermann P, Ising M, Kloiber S, Lucae S, Kunzel HE, Binder EB, Holsboer F, Uhr M. Changes in the hypothalamic-pituitary-adrenal axis and leptin levels during antidepressant treatment. Neuropsychobiology. 55: 28-35. PMID 17556850 DOI: 10.1159/000103573  0.322
2007 Unschuld PG, Ising M, Erhardt A, Lucae S, Kloiber S, Kohli M, Salyakina D, Welt T, Kern N, Lieb R, Uhr M, Binder EB, Müller-Myhsok B, Holsboer F, Keck ME. Polymorphisms in the serotonin receptor gene HTR2A are associated with quantitative traits in panic disorder. American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics. 144: 424-9. PMID 17440930 DOI: 10.1002/Ajmg.B.30412  0.314
2007 Erhardt A, Lucae S, Unschuld PG, Ising M, Kern N, Salyakina D, Lieb R, Uhr M, Binder EB, Keck ME, Müller-Myhsok B, Holsboer F. Association of polymorphisms in P2RX7 and CaMKKb with anxiety disorders. Journal of Affective Disorders. 101: 159-68. PMID 17197037 DOI: 10.1016/J.Jad.2006.11.016  0.368
2007 Ising M, Horstmann S, Kloiber S, Lucae S, Binder EB, Kern N, Künzel HE, Pfennig A, Uhr M, Holsboer F. Combined dexamethasone/corticotropin releasing hormone test predicts treatment response in major depression - a potential biomarker? Biological Psychiatry. 62: 47-54. PMID 17123470 DOI: 10.1016/J.Biopsych.2006.07.039  0.341
2007 Thoeringer CK, Binder EB, Salyakina D, Erhardt A, Ising M, Unschuld PG, Kern N, Lucae S, Brueckl TM, Mueller MB, Fuchs B, Puetz B, Lieb R, Uhr M, Holsboer F, et al. Association of a Met88Val diazepam binding inhibitor (DBI) gene polymorphism and anxiety disorders with panic attacks. Journal of Psychiatric Research. 41: 579-84. PMID 16904689 DOI: 10.1016/J.Jpsychires.2006.06.001  0.348
2006 Binder EB, Nemeroff CB. Implications for the practice of psychiatry. Progress in Brain Research. 158: 275-93. PMID 17027701 DOI: 10.1016/S0079-6123(06)58013-6  0.466
2006 Erhardt A, Ising M, Unschuld PG, Kern N, Lucae S, Pütz B, Uhr M, Binder EB, Holsboer F, Keck ME. Regulation of the hypothalamic-pituitary-adrenocortical system in patients with panic disorder. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 31: 2515-22. PMID 16841071 DOI: 10.1038/Sj.Npp.1301168  0.36
2006 Lucae S, Salyakina D, Barden N, Harvey M, Gagné B, Labbé M, Binder EB, Uhr M, Paez-Pereda M, Sillaber I, Ising M, Brückl T, Lieb R, Holsboer F, Müller-Myhsok B. P2RX7, a gene coding for a purinergic ligand-gated ion channel, is associated with major depressive disorder. Human Molecular Genetics. 15: 2438-45. PMID 16822851 DOI: 10.1093/Hmg/Ddl166  0.354
2006 Binder EB, Holsboer F. Pharmacogenomics and antidepressant drugs. Annals of Medicine. 38: 82-94. PMID 16581694 DOI: 10.1080/07853890600551045  0.341
2006 van Rossum EF, Binder EB, Majer M, Koper JW, Ising M, Modell S, Salyakina D, Lamberts SW, Holsboer F. Polymorphisms of the glucocorticoid receptor gene and major depression. Biological Psychiatry. 59: 681-8. PMID 16580345 DOI: 10.1016/J.Biopsych.2006.02.007  0.372
2005 Schumacher J, Jamra RA, Becker T, Ohlraun S, Klopp N, Binder EB, Schulze TG, Deschner M, Schmäl C, Höfels S, Zobel A, Illig T, Propping P, Holsboer F, Rietschel M, et al. Evidence for a relationship between genetic variants at the brain-derived neurotrophic factor (BDNF) locus and major depression. Biological Psychiatry. 58: 307-14. PMID 16005437 DOI: 10.1016/J.Biopsych.2005.04.006  0.365
2005 Ising M, Künzel HE, Binder EB, Nickel T, Modell S, Holsboer F. The combined dexamethasone/CRH test as a potential surrogate marker in depression. Progress in Neuro-Psychopharmacology & Biological Psychiatry. 29: 1085-93. PMID 15950349 DOI: 10.1016/J.Pnpbp.2005.03.014  0.351
2005 Pfennig A, Kunzel HE, Kern N, Ising M, Majer M, Fuchs B, Ernst G, Holsboer F, Binder EB. Hypothalamus-pituitary-adrenal system regulation and suicidal behavior in depression. Biological Psychiatry. 57: 336-42. PMID 15705348 DOI: 10.1016/J.Biopsych.2004.11.017  0.312
2005 Post A, Ohl F, Almeida OF, Binder EB, Rücker M, Welt S, Binder E, Holsboer F, Sillaber I. Identification of molecules potentially involved in mediating the in vivo actions of the corticotropin-releasing hormone receptor 1 antagonist, NBI30775 (R121919). Psychopharmacology. 180: 150-8. PMID 15682302 DOI: 10.1007/S00213-004-2134-X  0.322
2004 Binder EB, Salyakina D, Lichtner P, Wochnik GM, Ising M, Pütz B, Papiol S, Seaman S, Lucae S, Kohli MA, Nickel T, Künzel HE, Fuchs B, Majer M, Pfennig A, et al. Polymorphisms in FKBP5 are associated with increased recurrence of depressive episodes and rapid response to antidepressant treatment. Nature Genetics. 36: 1319-25. PMID 15565110 DOI: 10.1038/Ng1479  0.384
2004 Binder EB, Kinkead B, Owens MJ, Nemeroff CB. Neurotensin receptor antagonist SR 142948A alters Fos expression and extrapyramidal side effect profile of typical and atypical antipsychotic drugs. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 29: 2200-7. PMID 15328528 DOI: 10.1038/sj.npp.1300546  0.721
2003 Müller MB, Keck ME, Binder EB, Kresse AE, Hagemeyer TP, Landgraf R, Holsboer F, Uhr M. ABCB1 (MDR1)-type P-glycoproteins at the blood-brain barrier modulate the activity of the hypothalamic-pituitary-adrenocortical system: implications for affective disorder. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 28: 1991-9. PMID 12888779 DOI: 10.1038/Sj.Npp.1300257  0.327
2002 Binder EB, Gross RE, Nemeroff CB, Kilts CD. Effects of neurotensin receptor antagonism on latent inhibition in Sprague-Dawley rats. Psychopharmacology. 161: 288-95. PMID 12021832 DOI: 10.1007/s00213-002-1031-4  0.437
2001 Binder EB, Kinkead B, Owens MJ, Nemeroff CB. The role of neurotensin in the pathophysiology of schizophrenia and the mechanism of action of antipsychotic drugs. Biological Psychiatry. 50: 856-72. PMID 11743941 DOI: 10.1016/S0006-3223(01)01211-2  0.715
2001 Binder EB, Kinkead B, Owens MJ, Nemeroff CB. Neurotensin and dopamine interactions. Pharmacological Reviews. 53: 453-86. PMID 11734615  0.696
2001 Binder EB, Kinkead B, Owens MJ, Kilts CD, Nemeroff CB. Enhanced neurotensin neurotransmission is involved in the clinically relevant behavioral effects of antipsychotic drugs: evidence from animal models of sensorimotor gating. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 21: 601-8. PMID 11160439 DOI: 10.1523/Jneurosci.21-02-00601.2001  0.718
1999 Kinkead B, Binder EB, Nemeroff CB. Does neurotensin mediate the effects of antipsychotic drugs? Biological Psychiatry. 46: 340-51. PMID 10435199 DOI: 10.1016/S0006-3223(99)00070-0  0.671
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