Elisabeth B. Binder - Publications

Affiliations: 
Max Planck Instute of Psychiatry/Emory, München, Bayern, Germany 
Area:
Psychiatric Genetics

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Year Citation  Score
2023 Penner-Goeke S, Bothe M, Rek N, Kreitmaier P, Pöhlchen D, Kühnel A, Glaser LV, Kaya E, Krontira AC, Röh S, Czamara D, Ködel M, Monteserin-Garcia J, Diener L, Wölfel B, ... ... Binder EB, et al. High-throughput screening of glucocorticoid-induced enhancer activity reveals mechanisms of stress-related psychiatric disorders. Proceedings of the National Academy of Sciences of the United States of America. 120: e2305773120. PMID 38011552 DOI: 10.1073/pnas.2305773120  0.304
2023 Joseph J, Buss C, Knop A, de Punder K, Winter SM, Spors B, Binder E, Haynes JD, Heim C. Greater maltreatment severity is associated with smaller brain volume with implication for intellectual ability in young children. Neurobiology of Stress. 27: 100576. PMID 37810429 DOI: 10.1016/j.ynstr.2023.100576  0.422
2023 Bassil K, Krontira AC, Leroy T, Escoto AIH, Snijders C, Pernia CD, Pasterkamp RJ, de Nijs L, van den Hove D, Kenis G, Boks MP, Vadodaria K, Daskalakis NP, Binder EB, Rutten BPF. modeling of the neurobiological effects of glucocorticoids: A review. Neurobiology of Stress. 23: 100530. PMID 36891528 DOI: 10.1016/j.ynstr.2023.100530  0.611
2022 Winter SM, Dittrich K, Dörr P, Overfeld J, Moebus I, Murray E, Karaboycheva G, Zimmermann C, Knop A, Voelkle M, Entringer S, Buss C, Haynes JD, Binder EB, Heim C. Immediate impact of child maltreatment on mental, developmental, and physical health trajectories. Journal of Child Psychology and Psychiatry, and Allied Disciplines. PMID 35266137 DOI: 10.1111/jcpp.13550  0.4
2021 Godara M, Silveira S, Matthäus H, Heim C, Voelkle M, Hecht M, Binder EB, Singer T. Investigating differential effects of socio-emotional and mindfulness-based online interventions on mental health, resilience and social capacities during the COVID-19 pandemic: The study protocol. Plos One. 16: e0256323. PMID 34735441 DOI: 10.1371/journal.pone.0256323  0.408
2021 Dammering F, Martins J, Dittrich K, Czamara D, Rex-Haffner M, Overfeld J, de Punder K, Buss C, Entringer S, Winter SM, Binder EB, Heim C. The pediatric buccal epigenetic clock identifies significant ageing acceleration in children with internalizing disorder and maltreatment exposure. Neurobiology of Stress. 15: 100394. PMID 34621920 DOI: 10.1016/j.ynstr.2021.100394  0.463
2021 Martins J, Czamara D, Sauer S, Rex-Haffner M, Dittrich K, Dörr P, de Punder K, Overfeld J, Knop A, Dammering F, Entringer S, Winter SM, Buss C, Heim C, Binder EB. Childhood adversity correlates with stable changes in DNA methylation trajectories in children and converges with epigenetic signatures of prenatal stress. Neurobiology of Stress. 15: 100336. PMID 34095363 DOI: 10.1016/j.ynstr.2021.100336  0.461
2021 Lopez JP, Brivio E, Santambrogio A, De Donno C, Kos A, Peters M, Rost N, Czamara D, Brückl TM, Roeh S, Pöhlmann ML, Engelhardt C, Ressle A, Stoffel R, Tontsch A, ... ... Binder EB, et al. Single-cell molecular profiling of all three components of the HPA axis reveals adrenal ABCB1 as a regulator of stress adaptation. Science Advances. 7. PMID 33571131 DOI: 10.1126/sciadv.abe4497  0.418
2021 Czamara D, Tissink E, Tuhkanen J, Martins J, Awaloff Y, Drake AJ, Khulan B, Palotie A, Winter SM, Nemeroff CB, Craighead WE, Dunlop BW, Mayberg HS, Kinkead B, Mathew SJ, ... ... Binder EB, et al. Combined effects of genotype and childhood adversity shape variability of DNA methylation across age. Translational Psychiatry. 11: 88. PMID 33526782 DOI: 10.1038/s41398-020-01147-z  0.695
2020 Entringer S, de Punder K, Overfeld J, Karaboycheva G, Dittrich K, Buss C, Winter SM, Binder EB, Heim C. Immediate and longitudinal effects of maltreatment on systemic inflammation in young children. Development and Psychopathology. 32: 1725-1731. PMID 33427162 DOI: 10.1017/S0954579420001686  0.452
2020 Daskalakis NP, Xu C, Bader HN, Chatzinakos C, Weber P, Makotkine I, Lehrner A, Bierer LM, Binder EB, Yehuda R. Intergenerational trauma is associated with expression alterations in glucocorticoid- and immune-related genes. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 33173192 DOI: 10.1038/s41386-020-00900-8  0.585
2020 Hagenaars SP, Coleman JRI, Choi SW, Gaspar H, Adams MJ, Howard DM, Hodgson K, Traylor M, Air TM, Andlauer TFM, Arolt V, Baune BT, Binder EB, Blackwood DHR, Boomsma DI, et al. Genetic comorbidity between major depression and cardio-metabolic traits, stratified by age at onset of major depression. American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics. PMID 32681593 DOI: 10.1002/Ajmg.B.32807  0.323
2020 Rantalainen V, Binder EB, Lahti-Pulkkinen M, Czamara D, Laivuori H, Villa PM, Girchenko P, Kvist T, Hämäläinen E, Kajantie E, Lahti J, Räikkönen K. Polygenic prediction of the risk of perinatal depressive symptoms. Depression and Anxiety. PMID 32627298 DOI: 10.1002/da.23066  0.336
2020 Kühnel A, Kroemer NB, Elbau IG, Czisch M, Sämann PG, Walter M, Binder EB. Psychosocial stress reactivity habituates following acute physiological stress. Human Brain Mapping. PMID 32597537 DOI: 10.1002/Hbm.25106  0.332
2020 Krontira AC, Cruceanu C, Binder EB. Glucocorticoids as Mediators of Adverse Outcomes of Prenatal Stress. Trends in Neurosciences. 43: 394-405. PMID 32459992 DOI: 10.1016/j.tins.2020.03.008  0.362
2020 Brückl TM, Spoormaker VI, Sämann PG, Brem AK, Henco L, Czamara D, Elbau I, Grandi NC, Jollans L, Kühnel A, Leuchs L, Pöhlchen D, Schneider M, Tontsch A, Keck ME, ... ... Binder EB, et al. The biological classification of mental disorders (BeCOME) study: a protocol for an observational deep-phenotyping study for the identification of biological subtypes. Bmc Psychiatry. 20: 213. PMID 32393358 DOI: 10.1186/S12888-020-02541-Z  0.309
2020 Bierer LM, Bader HN, Daskalakis NP, Lehrner A, Provençal N, Wiechmann T, Klengel T, Makotkine I, Binder EB, Yehuda R. Intergenerational Effects of Maternal Holocaust Exposure on Methylation. The American Journal of Psychiatry. appiajp201919060618. PMID 32312110 DOI: 10.1176/Appi.Ajp.2019.19060618  0.607
2020 Arloth J, Eraslan G, Andlauer TFM, Martins J, Iurato S, Kühnel B, Waldenberger M, Frank J, Gold R, Hemmer B, Luessi F, Nischwitz S, Paul F, Wiendl H, Gieger C, ... ... Binder EB, et al. DeepWAS: Multivariate genotype-phenotype associations by directly integrating regulatory information using deep learning. Plos Computational Biology. 16: e1007616. PMID 32012148 DOI: 10.1371/Journal.Pcbi.1007616  0.329
2019 Penner-Goeke S, Binder EB. Epigenetics and depression
. Dialogues in Clinical Neuroscience. 21: 397-405. PMID 31949407 DOI: 10.31887/DCNS.2019.21.4/ebinder  0.367
2019 Jia T, Chu C, Liu Y, van Dongen J, Papastergios E, Armstrong NJ, Bastin ME, Carrillo-Roa T, den Braber A, Harris M, Jansen R, Liu J, Luciano M, Ori APS, Roiz Santiañez R, ... ... Binder EB, et al. Epigenome-wide meta-analysis of blood DNA methylation and its association with subcortical volumes: findings from the ENIGMA Epigenetics Working Group. Molecular Psychiatry. PMID 31811260 DOI: 10.1038/S41380-019-0605-Z  0.325
2019 Jiang S, Postovit L, Cattaneo A, Binder EB, Aitchison KJ. Epigenetic Modifications in Stress Response Genes Associated With Childhood Trauma. Frontiers in Psychiatry. 10: 808. PMID 31780969 DOI: 10.3389/Fpsyt.2019.00808  0.399
2019 McLean SA, Ressler K, Koenen KC, Neylan T, Germine L, Jovanovic T, Clifford GD, Zeng D, An X, Linnstaedt S, Beaudoin F, House S, Bollen KA, Musey P, Hendry P, ... ... Binder E, et al. The AURORA Study: a longitudinal, multimodal library of brain biology and function after traumatic stress exposure. Molecular Psychiatry. PMID 31745239 DOI: 10.1038/S41380-019-0581-3  0.341
2019 Forstner AJ, Awasthi S, Wolf C, Maron E, Erhardt A, Czamara D, Eriksson E, Lavebratt C, Allgulander C, Friedrich N, Becker J, Hecker J, Rambau S, Conrad R, Geiser F, ... ... Binder EB, et al. Genome-wide association study of panic disorder reveals genetic overlap with neuroticism and depression. Molecular Psychiatry. PMID 31712720 DOI: 10.1038/S41380-019-0590-2  0.308
2019 Thomas M, Coope A, Falkenberg C, Dunlop BW, Czamara D, Provencal N, Craighead WE, Mayberg HS, Nemeroff CB, Binder EB, Nieratschker V. Investigation of MORC1 DNA methylation as biomarker of early life stress and depressive symptoms. Journal of Psychiatric Research. 120: 154-162. PMID 31683097 DOI: 10.1016/j.jpsychires.2019.10.019  0.503
2019 Raffington L, Czamara D, Mohn JJ, Falck J, Schmoll V, Heim C, Binder EB, Shing YL. Stable longitudinal associations of family income with children's hippocampal volume and memory persist after controlling for polygenic scores of educational attainment. Developmental Cognitive Neuroscience. 40: 100720. PMID 31678692 DOI: 10.1016/j.dcn.2019.100720  0.478
2019 Aristizabal MJ, Anreiter I, Halldorsdottir T, Odgers CL, McDade TW, Goldenberg A, Mostafavi S, Kobor MS, Binder EB, Sokolowski MB, O'Donnell KJ. Biological embedding of experience: A primer on epigenetics. Proceedings of the National Academy of Sciences of the United States of America. PMID 31624126 DOI: 10.1073/Pnas.1820838116  0.313
2019 Ing A, Sämann PG, Chu C, Tay N, Biondo F, Robert G, Jia T, Wolfers T, Desrivières S, Banaschewski T, Bokde ALW, Bromberg U, Büchel C, Conrod P, Fadai T, ... ... Binder E, et al. Identification of neurobehavioural symptom groups based on shared brain mechanisms. Nature Human Behaviour. PMID 31591521 DOI: 10.1038/S41562-019-0738-8  0.316
2019 Glanville KP, Coleman JRI, Hanscombe KB, Euesden J, Choi SW, Purves KL, Breen G, Air TM, Andlauer TFM, Baune BT, Binder EB, Blackwood DHR, Boomsma DI, Buttenschøn HN, Colodro-Conde L, et al. Classical Human Leukocyte Antigen Alleles and C4 Haplotypes Are Not Significantly Associated With Depression. Biological Psychiatry. PMID 31570195 DOI: 10.1016/J.Biopsych.2019.06.031  0.335
2019 Provençal N, Arloth J, Cattaneo A, Anacker C, Cattane N, Wiechmann T, Röh S, Ködel M, Klengel T, Czamara D, Müller NS, Lahti J, Räikkönen K, Pariante CM, ... Binder EB, et al. Glucocorticoid exposure during hippocampal neurogenesis primes future stress response by inducing changes in DNA methylation. Proceedings of the National Academy of Sciences of the United States of America. PMID 31399550 DOI: 10.1073/Pnas.1820842116  0.353
2019 Lebow MA, Schroeder M, Tsoory M, Holzman-Karniel D, Mehta D, Ben-Dor S, Gil S, Bradley B, Smith AK, Jovanovic T, Ressler KJ, Binder EB, Chen A. Glucocorticoid-induced leucine zipper "quantifies" stressors and increases male susceptibility to PTSD. Translational Psychiatry. 9: 178. PMID 31346158 DOI: 10.1038/S41398-019-0509-3  0.356
2019 Kazmi N, Sharp GC, Reese SE, Vehmeijer FO, Lahti J, Page CM, Zhang W, Rifas-Shiman SL, Rezwan FI, Simpkin AJ, Burrows K, Richardson TG, Santos Ferreira DL, Fraser A, Harmon QE, ... ... Binder EB, et al. Hypertensive Disorders of Pregnancy and DNA Methylation in Newborns. Hypertension (Dallas, Tex. : 1979). HYPERTENSIONAHA11912. PMID 31230546 DOI: 10.1161/Hypertensionaha.119.12634  0.32
2019 Elbau IG, Cruceanu C, Binder EB. Genetics of Resilience: Gene-by-Environment Interaction Studies as a Tool to Dissect Mechanisms of Resilience. Biological Psychiatry. PMID 31202489 DOI: 10.1016/j.biopsych.2019.04.025  0.304
2019 Czamara D, Eraslan G, Page CM, Lahti J, Lahti-Pulkkinen M, Hämäläinen E, Kajantie E, Laivuori H, Villa PM, Reynolds RM, Nystad W, Håberg SE, London SJ, O'Donnell KJ, Garg E, ... ... Binder EB, et al. Integrated analysis of environmental and genetic influences on cord blood DNA methylation in new-borns. Nature Communications. 10: 2548. PMID 31186427 DOI: 10.1038/S41467-019-10461-0  0.316
2019 Wiechmann T, Röh S, Sauer S, Czamara D, Arloth J, Ködel M, Beintner M, Knop L, Menke A, Binder EB, Provençal N. Identification of dynamic glucocorticoid-induced methylation changes at the FKBP5 locus. Clinical Epigenetics. 11: 83. PMID 31122292 DOI: 10.1186/s13148-019-0682-5  0.349
2019 Zannas AS, Jia M, Hafner K, Baumert J, Wiechmann T, Pape JC, Arloth J, Ködel M, Martinelli S, Roitman M, Röh S, Haehle A, Emeny RT, Iurato S, Carrillo-Roa T, ... ... Binder EB, et al. Epigenetic upregulation of FKBP5 by aging and stress contributes to NF-κB-driven inflammation and cardiovascular risk. Proceedings of the National Academy of Sciences of the United States of America. PMID 31113877 DOI: 10.1073/Pnas.1816847116  0.364
2019 Mehta D, Rex-Haffner M, Søndergaard HB, Pinborg A, Binder EB, Frokjaer VG. Genome-wide gene expression in a pharmacological hormonal transition model and its relation to depressive symptoms. Acta Psychiatrica Scandinavica. PMID 31099405 DOI: 10.1111/acps.13038  0.338
2019 Küpers LK, Monnereau C, Sharp GC, Yousefi P, Salas LA, Ghantous A, Page CM, Reese SE, Wilcox AJ, Czamara D, Starling AP, Novoloaca A, Lent S, Roy R, Hoyo C, ... ... Binder EB, et al. Meta-analysis of epigenome-wide association studies in neonates reveals widespread differential DNA methylation associated with birthweight. Nature Communications. 10: 1893. PMID 31015461 DOI: 10.1038/S41467-019-09671-3  0.304
2019 Athreya AP, Neavin D, Carrillo-Roa T, Skime M, Biernacka J, Frye MA, Rush AJ, Wang L, Binder EB, Iyer RK, Weinshilboum RM, Bobo WV. Pharmacogenomics-Driven Prediction of Antidepressant Treatment Outcomes: A Machine Learning Approach with Multi-Trial Replication. Clinical Pharmacology and Therapeutics. PMID 31012492 DOI: 10.1002/Cpt.1482  0.309
2019 Ramo-Fernández L, Boeck C, Koenig AM, Schury K, Binder EB, Gündel H, Fegert JM, Karabatsiakis A, Kolassa IT. The effects of childhood maltreatment on epigenetic regulation of stress-response associated genes: an intergenerational approach. Scientific Reports. 9: 983. PMID 31000782 DOI: 10.1038/s41598-018-36689-2  0.385
2019 Piechaczek CE, Greimel E, Feldmann L, Pehl V, Allgaier AK, Frey M, Freisleder FJ, Halldorsdottir T, Binder EB, Ising M, Schulte-Körne G. Interactions between FKBP5 variation and environmental stressors in adolescent Major Depression. Psychoneuroendocrinology. 106: 28-37. PMID 30953930 DOI: 10.1016/J.Psyneuen.2019.03.025  0.37
2019 Halldorsdottir T, Kurtoic D, Müller-Myhsok B, Binder EB, Blair C. Neurobiology of Self-Regulation: Longitudinal Influence of FKBP5 and Intimate Partner Violence on Emotional and Cognitive Development in Childhood. The American Journal of Psychiatry. appiajp201918091018. PMID 30947533 DOI: 10.1176/Appi.Ajp.2019.18091018  0.321
2019 Halldorsdottir T, Piechaczek C, Soares de Matos AP, Czamara D, Pehl V, Wagenbuechler P, Feldmann L, Quickenstedt-Reinhardt P, Allgaier AK, Freisleder FJ, Greimel E, Kvist T, Lahti J, Räikkönen K, Rex-Haffner M, ... ... Binder EB, et al. Polygenic Risk: Predicting Depression Outcomes in Clinical and Epidemiological Cohorts of Youths. The American Journal of Psychiatry. appiajp201918091014. PMID 30947532 DOI: 10.1176/Appi.Ajp.2019.18091014  0.342
2019 Bin Wei Y, McCarthy M, Ren H, Carrillo-Roa T, Shekhtman T, DeModena A, Liu JJ, Leckband SG, Mors O, Rietschel M, Henigsberg N, Cattaneo A, Binder EB, Aitchison KJ, Kelsoe JR. A functional variant in the serotonin receptor 7 gene (HTR7), rs7905446, is associated with good response to SSRIs in bipolar and unipolar depression. Molecular Psychiatry. PMID 30874608 DOI: 10.1038/S41380-019-0397-1  0.379
2019 Toepfer P, O Donnell KJ, Entringer S, Heim CM, Lin DTS, MacIsaac JL, Kobor MS, Meaney MJ, Provençal N, Binder EB, Wadhwa PD, Buss C. A Role of Oxytocin Receptor Gene Brain Tissue Expression Quantitative Trait Locus rs237895 in the Intergenerational Transmission of the Effects of Maternal Childhood Maltreatment. Journal of the American Academy of Child and Adolescent Psychiatry. PMID 30858011 DOI: 10.1016/J.Jaac.2019.03.006  0.532
2019 Rowson SA, Bekhbat M, Kelly SD, Binder EB, Hyer MM, Shaw G, Bent MA, Hodes G, Tharp G, Weinshenker D, Qin Z, Neigh GN. Chronic adolescent stress sex-specifically alters the hippocampal transcriptome in adulthood. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 30710108 DOI: 10.1038/S41386-019-0321-Z  0.594
2019 Zimmermann CA, Arloth J, Santarelli S, Löschner A, Weber P, Schmidt MV, Spengler D, Binder EB. Stress dynamically regulates co-expression networks of glucocorticoid receptor-dependent MDD and SCZ risk genes. Translational Psychiatry. 9: 41. PMID 30696808 DOI: 10.1038/S41398-019-0373-1  0.389
2019 Toepfer P, O'Donnell KJ, Entringer S, Garg E, Heim CM, Lin DTS, MacIsaac JL, Kobor MS, Meaney MJ, Provençal N, Binder EB, Wadhwa PD, Buss C. Dynamic DNA methylation changes in the maternal oxytocin gene locus (OXT) during pregnancy predict postpartum maternal intrusiveness. Psychoneuroendocrinology. 103: 156-162. PMID 30690225 DOI: 10.1016/J.Psyneuen.2019.01.013  0.5
2019 Binder EB. [Environment and epigenetics]. Der Nervenarzt. PMID 30643952 DOI: 10.1007/s00115-018-0657-3  0.323
2019 Overfeld J, Buss C, Punder Kd, Winter S, Haynes J, Binder EB, Heim C. Immediate biological embedding of maltreatment in children: Moderating effects of FK506 binding protein 5 (FKBP5) gene on cortisol reactivity and amygdala volume in children aged 3–5 years Psychoneuroendocrinology. 107: 64-64. DOI: 10.1016/J.Psyneuen.2019.07.185  0.479
2019 Dammering F, Martins J, Hoffmann F, Provencal N, Punder Kd, Overfeld J, Czamara D, Rex-Haffner M, McEwen L, Kobor M, Winter S, Buss C, Entringer S, Binder E, Heim C. Psychiatric symptom severity mediates the effect of adversity on epigenetic aging in children aged 3-5 years Psychoneuroendocrinology. 107: 30-30. DOI: 10.1016/J.Psyneuen.2019.07.084  0.498
2019 Overfeld J, Buss C, Punder Kd, Winter S, Haynes J, Binder E, Heim C. Childhood maltreatment severity is associated with smaller total brain size in preschool age children Psychoneuroendocrinology. 107: 5-6. DOI: 10.1016/J.Psyneuen.2019.07.012  0.474
2019 Karaboycheva GD, Punder Kd, Overfeld J, Doerr P, Dittrich K, Murray E, Binder E, Winter S, Entringer S, Heim C. Intestinal dysbiosis in maltreated children is associated with concentrations of salivary cortisol, C-reactive protein and with depressive symptoms Psychoneuroendocrinology. 107: 3-3. DOI: 10.1016/J.Psyneuen.2019.07.007  0.508
2019 Dammering F, McEwen L, Provencal N, Punder Kd, Overfeld J, Martins J, Czamara D, Rex-Haffner M, Hoffmann F, Kobor M, Buss C, Winter S, Entringer S, Binder E, Heim C. Bidirectional effect of early adversity on epigenetic ageing in children: Mediation by C-reactive protein and moderation by FKBP5 gene and cortisol status Psychoneuroendocrinology. 100. DOI: 10.1016/J.Psyneuen.2018.12.169  0.51
2019 Toepfer P, O’Donnell KJ, Entringer S, Heim CM, Lin DT, MacIsaac JL, Kobor MS, Meaney MJ, Provencal N, Binder EB, Wadhwa PD, Buss C. OXTR brain tissue expression quantitative locus rs237895 moderates the association between maternal childhood maltreatment and non-optimal maternal behavior with implications for offspring socio-emotional development and attachment security Psychoneuroendocrinology. 100: S48. DOI: 10.1016/J.Psyneuen.2018.12.167  0.498
2019 Shaw GA, Bekhbat M, Rowson SA, Bent MA, Hodes G, Binder E, Neigh G. Female wistar rats with a history of chronic adolescent stress demonstrate decreased hippocampal DNA methylation in adulthood Psychoneuroendocrinology. 100: S25. DOI: 10.1016/J.Psyneuen.2018.12.093  0.579
2019 Punder Kd, Overfeld J, Karaboycheva G, Winter S, Buss C, Binder EB, Heim C. Elevated C-reactive protein levels in children aged 3–5 years with verified exposure to maltreatment: Sex differences and association with depressive symptoms Psychoneuroendocrinology. 100. DOI: 10.1016/J.Psyneuen.2018.12.089  0.522
2019 Penner-Goeke S, Roeh S, Jakovcevski M, Binder E. S57Identifying Glucocorticoid Receptor Mediated Mechanisms Of Polygene-Environment Interactions Involved In Stress Sensitivity European Neuropsychopharmacology. 29. DOI: 10.1016/J.Euroneuro.2019.08.058  0.314
2019 Kero H, Raikkonen K, Lahti M, Cattaneo A, Czamara D, Binder E, Lahti J. FoxO1 variation modifies associations between maternal depression and anxiety during pregnancy and offspring psychiatric problems in early childhood European Neuropsychopharmacology. 29. DOI: 10.1016/J.Euroneuro.2019.08.011  0.328
2019 Freitag CM, Binder E. Epigenetic findings in childhood onset psychiatric disorders European Neuropsychopharmacology. 29: 1036-1036. DOI: 10.1016/J.Euroneuro.2018.07.034  0.311
2019 Czamara D, Eraslan G, Suarez A, Girchenko P, Lahti J, Lahti M, Hämäläinen E, Kajantie E, Laivuori H, Reynolds RM, Kondofersky I, Müller NS, Theis FJ, Räikkönen K, Binder EB. WHAT SHAPES THE CHILD'S EPIGENOME: GENOTYPE, PRENATAL ENVIRONMENT OR BOTH? European Neuropsychopharmacology. 29: S985. DOI: 10.1016/j.euroneuro.2017.08.363  0.342
2019 Awaloff Y, Provencal N, Carrillo-Roa T, Halldorsdottir T, Boadie D, Mayberg H, Craighed E, Czamara D, Binder E. Interactions Between Genotype And Environment Have A Strong Effect On Variability In Dna Methylation In Psychiatric Patients European Neuropsychopharmacology. 29. DOI: 10.1016/J.Euroneuro.2017.08.361  0.357
2019 Binder E, Burmeister M. Mechanisms of Early Adversity Associated Increases In Risk For Psychiatric Disorders European Neuropsychopharmacology. 29: S746-S747. DOI: 10.1016/j.euroneuro.2017.06.085  0.396
2019 de KP, Overfeld J, Karaboycheva G, Dittrich K, Winter SM, Buss C, Binder EB, Entringer S, Heim C. Abstract #4336 C-reactive protein levels in children aged 3–5 years with verified exposure to maltreatment: Sex differences and association with depression Brain Behavior and Immunity. 81: 35. DOI: 10.1016/J.Bbi.2019.08.119  0.513
2018 Mehta D, Rex-Haffner M, Søndergaard HB, Pinborg A, Binder EB, Frokjaer VG. Evidence for oestrogen sensitivity in perinatal depression: pharmacological sex hormone manipulation study. The British Journal of Psychiatry : the Journal of Mental Science. 1-9. PMID 30457060 DOI: 10.1192/bjp.2018.234  0.344
2018 Pape JC, Carrillo-Roa T, Rothbaum BO, Nemeroff CB, Czamara D, Zannas AS, Iosifescu D, Mathew SJ, Neylan TC, Mayberg HS, Dunlop BW, Binder EB. DNA methylation levels are associated with CRF receptor antagonist treatment outcome in women with post-traumatic stress disorder. Clinical Epigenetics. 10: 136. PMID 30390684 DOI: 10.1186/s13148-018-0569-x  0.509
2018 Kelley ME, Dunlop BW, Nemeroff CB, Lori A, Carrillo-Roa T, Binder EB, Kutner MH, Rivera VA, Craighead WE, Mayberg HS. Response rate profiles for major depressive disorder: Characterizing early response and longitudinal nonresponse. Depression and Anxiety. PMID 30260539 DOI: 10.1002/da.22832  0.453
2018 Elbau IG, Brücklmeier B, Uhr M, Arloth J, Czamara D, Spoormaker VI, Czisch M, Stephan KE, Binder EB, Sämann PG. The brain's hemodynamic response function rapidly changes under acute psychosocial stress in association with genetic and endocrine stress response markers. Proceedings of the National Academy of Sciences of the United States of America. PMID 30201713 DOI: 10.1073/pnas.1804340115  0.364
2018 Engel M, Eggert C, Kaplick PM, Eder M, Röh S, Tietze L, Namendorf C, Arloth J, Weber P, Rex-Haffner M, Geula S, Jakovcevski M, Hanna JH, Leshkowitz D, Uhr M, ... ... Binder EB, et al. The Role of mA/m-RNA Methylation in Stress Response Regulation. Neuron. 99: 389-403.e9. PMID 30048615 DOI: 10.1016/J.Neuron.2018.07.009  0.333
2018 Roeh S, Wiechmann T, Sauer S, Ködel M, Binder EB, Provençal N. HAM-TBS: high-accuracy methylation measurements via targeted bisulfite sequencing. Epigenetics & Chromatin. 11: 39. PMID 29973294 DOI: 10.1186/s13072-018-0209-x  0.321
2018 Mehta D, Bruenig D, Lawford B, Harvey W, Carrillo-Roa T, Morris CP, Jovanovic T, Young RM, Binder EB, Voisey J. Accelerated DNA methylation aging and increased resilience in veterans: The biological cost for soldiering on. Neurobiology of Stress. 8: 112-119. PMID 29888306 DOI: 10.1016/J.Ynstr.2018.04.001  0.31
2018 Zannas AS, Arloth J, Carrillo-Roa T, Iurato S, Röh S, Ressler KJ, Nemeroff CB, Smith AK, Bradley B, Heim C, Menke A, Lange JF, Brückl T, Ising M, Wray NR, ... ... Binder EB, et al. Correction to: Lifetime stress accelerates epigenetic aging in an urban, African American cohort: relevance of glucocorticoid signaling. Genome Biology. 19: 61. PMID 29792225 DOI: 10.1186/S13059-018-1441-1  0.555
2018 Suarez A, Lahti J, Czamara D, Lahti-Pulkkinen M, Knight AK, Girchenko P, Hämäläinen E, Kajantie E, Lipsanen J, Laivuori H, Villa PM, Reynolds RM, Smith AK, Binder EB, Räikkönen K. The Epigenetic Clock at Birth: Associations With Maternal Antenatal Depression and Child Psychiatric Problems. Journal of the American Academy of Child and Adolescent Psychiatry. 57: 321-328.e2. PMID 29706161 DOI: 10.1016/j.jaac.2018.02.011  0.346
2018 Wray NR, Ripke S, Mattheisen M, Trzaskowski M, Byrne EM, Abdellaoui A, Adams MJ, Agerbo E, Air TM, Andlauer TMF, Bacanu SA, Bækvad-Hansen M, Beekman AFT, Bigdeli TB, Binder EB, et al. Genome-wide association analyses identify 44 risk variants and refine the genetic architecture of major depression. Nature Genetics. PMID 29700475 DOI: 10.1038/S41588-018-0090-3  0.36
2018 Koenig AM, Ramo-Fernández L, Boeck C, Umlauft M, Pauly M, Binder EB, Kirschbaum C, Gündel H, Karabatsiakis A, Kolassa IT. Intergenerational gene × environment interaction of FKBP5 and childhood maltreatment on hair steroids. Psychoneuroendocrinology. 92: 103-112. PMID 29674169 DOI: 10.1016/J.Psyneuen.2018.04.002  0.336
2018 Matosin N, Halldorsdottir T, Binder EB. Understanding the Molecular Mechanisms Underpinning Gene by Environment Interactions in Psychiatric Disorders: The FKBP5 Model. Biological Psychiatry. PMID 29573791 DOI: 10.1016/j.biopsych.2018.01.021  0.386
2018 Rampp C, Eichelkraut A, Best J, Czamara D, Rex-Haffner M, Uhr M, Binder EB, Menke A. Sex-related differential response to dexamethasone in endocrine and immune measures in depressed in-patients and healthy controls. Journal of Psychiatric Research. 98: 107-115. PMID 29331929 DOI: 10.1016/j.jpsychires.2017.12.020  0.341
2018 Naik RR, Sotnikov SV, Diepold RP, Iurato S, Markt PO, Bultmann A, Brehm N, Mattheus T, Lutz B, Erhardt A, Binder EB, Schmidt U, Holsboer F, Landgraf R, Czibere L. Polymorphism in Tmem132d regulates expression and anxiety-related behavior through binding of RNA polymerase II complex. Translational Psychiatry. 8: 1. PMID 29317594 DOI: 10.1038/S41398-017-0025-2  0.344
2018 Cattaneo A, Cattane N, Malpighi C, Czamara D, Suarez A, Mariani N, Kajantie E, Luoni A, Eriksson JG, Lahti J, Mondelli V, Dazzan P, Räikkönen K, Binder EB, Riva MA, et al. FoxO1, A2M, and TGF-β1: three novel genes predicting depression in gene X environment interactions are identified using cross-species and cross-tissues transcriptomic and miRNomic analyses. Molecular Psychiatry. PMID 29302075 DOI: 10.1038/s41380-017-0002-4  0.384
2018 Criado-Marrero M, Rein T, Binder EB, Porter JT, Koren J, Blair LJ. Hsp90 and FKBP51: complex regulators of psychiatric diseases. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 373. PMID 29203717 DOI: 10.1098/Rstb.2016.0532  0.401
2018 Pape J, Carrillo-Roa T, Wiechmann T, Roeh S, Rothbaum B, Nemeroff C, Czamara D, Zannas A, Iosifescu D, Mathew S, Neylan T, Mayberg H, Dunlop B, Binder E. F179. Epigenetic Biomarkers in Women With Posttraumatic Stress Disorder After CRF1 Receptor Antagonist Treatment Biological Psychiatry. 83. DOI: 10.1016/J.Biopsych.2018.02.793  0.459
2017 Binder EB. Dissecting the molecular mechanisms of gene x environment interactions: implications for diagnosis and treatment of stress-related psychiatric disorders. European Journal of Psychotraumatology. 8: 1412745. PMID 29372006 DOI: 10.1080/20008198.2017.1412745  0.369
2017 Carrillo-Roa T, Labermaier C, Weber P, Herzog DP, Lareau C, Santarelli S, Wagner KV, Rex-Haffner M, Harbich D, Scharf SH, Nemeroff CB, Dunlop BW, Craighead WE, Mayberg HS, Schmidt MV, ... ... Binder EB, et al. Common genes associated with antidepressant response in mouse and man identify key role of glucocorticoid receptor sensitivity. Plos Biology. 15: e2002690. PMID 29283992 DOI: 10.1371/Journal.Pbio.2002690  0.489
2017 Iurato S, Carrillo-Roa T, Arloth J, Czamara D, Diener-Hölzl L, Lange J, Müller-Myhsok B, Binder EB, Erhardt A. "DNA Methylation signatures in panic disorder". Translational Psychiatry. 7: 1287. PMID 29249830 DOI: 10.1038/s41398-017-0026-1  0.304
2017 O'Connell CP, Goldstein-Piekarski AN, Nemeroff CB, Schatzberg AF, Debattista C, Carrillo-Roa T, Binder EB, Dunlop BW, Craighead WE, Mayberg HS, Williams LM. Antidepressant Outcomes Predicted by Genetic Variation in Corticotropin-Releasing Hormone Binding Protein. The American Journal of Psychiatry. appiajp201717020172. PMID 29241359 DOI: 10.1176/Appi.Ajp.2017.17020172  0.392
2017 Harms MB, Birn R, Provencal N, Wiechmann T, Binder EB, Giakas SW, Roeber BJ, Pollak SD. Early life stress, FK506 binding protein 5 gene (FKBP5) methylation, and inhibition-related prefrontal function: A prospective longitudinal study. Development and Psychopathology. 29: 1895-1903. PMID 29162190 DOI: 10.1017/S095457941700147X  0.365
2017 Breen MS, Tylee DS, Maihofer AX, Neylan TC, Mehta D, Binder E, Chandler SD, Hess JL, Kremen WS, Risbrough VB, Woelk CH, Baker DG, Nievergelt CM, Tsuang MT, Buxbaum JD, et al. PTSD Blood Transcriptome Mega-Analysis: Shared Inflammatory Pathways Across Biological Sex and Modes of Trauma. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 28925389 DOI: 10.1038/Npp.2017.220  0.322
2017 Dunlop BW, Binder EB, Iosifescu D, Mathew SJ, Neylan TC, Pape JC, Carrillo-Roa T, Green C, Kinkead B, Grigoriadis D, Rothbaum BO, Nemeroff CB, Mayberg HS. Corticotropin-Releasing Factor Receptor 1 Antagonism Is Ineffective for Women With Posttraumatic Stress Disorder. Biological Psychiatry. PMID 28793974 DOI: 10.1016/j.biopsych.2017.06.024  0.691
2017 Agís-Balboa RC, Pinhero P, Rebola N, Kerimoglu C, Benito E, Gertig M, Bahari-Javan S, Jain G, Burkhardt S, Delalle I, Jatzko A, Dettenhofer M, Zunszain PA, Schmitt A, Falkai P, ... ... Binder EB, et al. Formin 2 links neuropsychiatric phenotypes at young age to an increased risk for dementia. The Embo Journal. PMID 28768717 DOI: 10.15252/Embj.201796821  0.303
2017 Dedic N, Pöhlmann ML, Richter JS, Mehta D, Czamara D, Metzger MW, Dine J, Bedenk BT, Hartmann J, Wagner KV, Jurik A, Almli LM, Lori A, Moosmang S, Hofmann F, ... ... Binder EB, et al. Cross-disorder risk gene CACNA1C differentially modulates susceptibility to psychiatric disorders during development and adulthood. Molecular Psychiatry. PMID 28696432 DOI: 10.1038/Mp.2017.133  0.395
2017 Halldorsdottir T, de Matos APS, Awaloff Y, Arnarson EÖ, Craighead WE, Binder EB. FKBP5 moderation of the relationship between childhood trauma and maladaptive emotion regulation strategies in adolescents. Psychoneuroendocrinology. 84: 61-65. PMID 28654774 DOI: 10.1016/j.psyneuen.2017.06.012  0.348
2017 Emeny RT, Baumert J, Zannas AS, Kunze S, Wahl S, Iurato S, Arloth J, Erhardt A, Balsevich G, Schmidt MV, Weber P, Kretschmer A, Pfeiffer L, Kruse J, Strauch K, ... ... Binder EB, et al. Anxiety Associated Increased CpG Methylation In The Promoter of Asb1: A Translational Approach Evidenced By Epidemiological And Clinical Studies And A Murine Model. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 28540928 DOI: 10.1038/npp.2017.102  0.381
2017 Freytag V, Carrillo-Roa T, Milnik A, Sämann PG, Vukojevic V, Coynel D, Demougin P, Egli T, Gschwind L, Jessen F, Loos E, Maier W, Riedel-Heller SG, Scherer M, Vogler C, ... ... Binder EB, et al. A peripheral epigenetic signature of immune system genes is linked to neocortical thickness and memory. Nature Communications. 8: 15193. PMID 28443631 DOI: 10.1038/Ncomms15193  0.342
2017 Binder EB. Understanding gene × early adversity interactions: possibilities for insight in the biology of psychiatric disorders. European Archives of Psychiatry and Clinical Neuroscience. PMID 28271247 DOI: 10.1007/s00406-017-0775-0  0.326
2017 Santarelli S, Zimmermann C, Kalideris G, Lesuis SL, Arloth J, Uribe A, Dournes C, Balsevich G, Hartmann J, Masana M, Binder EB, Spengler D, Schmidt MV. An adverse early life environment can enhance stress resilience in adulthood. Psychoneuroendocrinology. 78: 213-221. PMID 28219813 DOI: 10.1016/J.Psyneuen.2017.01.021  0.346
2017 Maddox SA, Kilaru V, Shin J, Jovanovic T, Almli LM, Dias BG, Norrholm SD, Fani N, Michopoulos V, Ding Z, Conneely KN, Binder EB, Ressler KJ, Smith AK. Estrogen-dependent association of HDAC4 with fear in female mice and women with PTSD. Molecular Psychiatry. PMID 28093566 DOI: 10.1038/Mp.2016.250  0.36
2017 Toepfer P, ÓDonnell KJ, Heim CM, Lin DT, MacIsaac JL, Kobor MS, Meaney MJ, Provencal N, Binder EB, Entringer S, Wadhwa PD, Buss C. Dynamic DNA methylation changes in the oxytocin locus (OXT) during pregnancy are associated with maternal parenting behavior Psychoneuroendocrinology. 83: 25. DOI: 10.1016/J.Psyneuen.2017.07.306  0.483
2017 Carrillo-Roa T, Boadie D, McGrath C, Müller-Myhsok B, Craighed E, Mayberg H, Binder E. Polygenic Scores Derived From Neuroimaging Endophenotypes Predict Outcomes To Psychotherapy And Medication Treatments For Major Depressive Disorder European Neuropsychopharmacology. 27. DOI: 10.1016/J.Euroneuro.2016.09.576  0.346
2017 Cruceanu C, Matosin N, Binder EB. Interactions of early-life stress with the genome and epigenome: from prenatal stress to psychiatric disorders Current Opinion in Behavioral Sciences. 14: 167-171. DOI: 10.1016/j.cobeha.2017.04.001  0.374
2017 Clive M, Jones I, Wilcox H, Eaton W, Eck KV, Binder E, Osborne L, Payne J, Frokjaer V, Kaminsky Z. 357. Stress Vulnerability and Epigenetic Variation of a Suicide Biomarker Gene, Molecular Regulation and Neuroimaging Consequences of SKA2 Biological Psychiatry. 81. DOI: 10.1016/J.Biopsych.2017.02.374  0.338
2017 Wingo A, Lori A, Gillespie C, Kerley K, Jovanovic T, Binder E, Bradley B, Ressler K. 230. Transcriptome-wide Analysis Identified Differential Expression of PID1, a Gene Implicated in Insulin Resistance, in High versus Low Psychological Resilience Biological Psychiatry. 81: S94-S95. DOI: 10.1016/J.Biopsych.2017.02.244  0.59
2017 Kaminsky Z, Jones I, Bakker A, Wadhwa P, Entringer S, Osborne L, Binder E, Frokjaer V, Buss C, Payne J. 561. Discovery, Replication, and Application of an Epigenetic Biomarker Model to the Prediction of Postpartum Depression and Neuroimaging Endophenotypes Biological Psychiatry. 81: S227. DOI: 10.1016/J.Biopsych.2017.02.1169  0.303
2017 Pape J, Carrillo-Roa T, Iosifescu D, Mathew S, Neylan T, Nemeroff C, Mayberg H, Dunlop B, Binder E. 549. DNA Methylation Biomarkers and Treatment Effects of a Corticotropin Releasing Hormone Type 1 Receptor Antagonist in a Biologically-Defined Subset of PTSD-Patients Biological Psychiatry. 81. DOI: 10.1016/J.Biopsych.2017.02.1157  0.451
2017 Yehuda R, Bierer LM, Bader HN, Daskalakis NP, Klengel T, Binder E. 90. Second Generation Effects of Trauma: Evidence for Developmental Programming Biological Psychiatry. 81: S38. DOI: 10.1016/J.Biopsych.2017.02.102  0.567
2016 Toepfer P, Heim C, Entringer S, Binder E, Wadhwa P, Buss C. Oxytocin pathways in the intergenerational transmission of maternal early life stress. Neuroscience and Biobehavioral Reviews. 73: 293-308. PMID 28027955 DOI: 10.1016/J.Neubiorev.2016.12.026  0.553
2016 Piyasena C, Cartier J, Provençal N, Wiechmann T, Khulan B, Sunderasan R, Menon G, Seckl JR, Reynolds RM, Binder EB, Drake AJ. Dynamic Changes in DNA Methylation Occur during the First Year of Life in Preterm Infants. Frontiers in Endocrinology. 7: 158. PMID 28018293 DOI: 10.3389/fendo.2016.00158  0.309
2016 Volk N, Pape JC, Engel M, Zannas AS, Cattane N, Cattaneo A, Binder EB, Chen A. Amygdalar MicroRNA-15a Is Essential for Coping with Chronic Stress. Cell Reports. 17: 1882-1891. PMID 27829158 DOI: 10.1016/J.Celrep.2016.10.038  0.347
2016 Halldorsdottir T, Binder EB. Gene × Environment Interactions: From Molecular Mechanisms to Behavior. Annual Review of Psychology. PMID 27732803 DOI: 10.1146/annurev-psych-010416-044053  0.326
2016 Knight AK, Craig JM, Theda C, Bækvad-Hansen M, Bybjerg-Grauholm J, Hansen CS, Hollegaard MV, Hougaard DM, Mortensen PB, Weinsheimer SM, Werge TM, Brennan PA, Cubells JF, Newport DJ, Stowe ZN, ... ... Binder EB, et al. An epigenetic clock for gestational age at birth based on blood methylation data. Genome Biology. 17: 206. PMID 27717399 DOI: 10.1186/S13059-016-1068-Z  0.547
2016 Grünewald L, Landaas ET, Geissler J, Weber H, Quast C, Röh S, Schartner C, Lesch KP, Romanos M, Kittel-Schneider S, Binder E, Reif A. Functional Impact of an ADHD-Associated DIRAS2 Promoter Polymorphism. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 27364329 DOI: 10.1038/Npp.2016.113  0.311
2016 Gassen NC, Chrousos GP, Binder EB, Zannas AS. Life stress, glucocorticoid signaling, and the aging epigenome: implications for aging-related diseases. Neuroscience and Biobehavioral Reviews. PMID 27343999 DOI: 10.1016/j.neubiorev.2016.06.003  0.332
2016 Kilaru V, Iyer SV, Almli LM, Stevens JS, Lori A, Jovanovic T, Ely TD, Bradley B, Binder EB, Koen N, Stein DJ, Conneely KN, Wingo AP, Smith AK, Ressler KJ. Genome-wide gene-based analysis suggests an association between Neuroligin 1 (NLGN1) and post-traumatic stress disorder. Translational Psychiatry. 6: e820. PMID 27219346 DOI: 10.1038/Tp.2016.69  0.374
2016 Trost S, Diekhof EK, Mohr H, Vieker H, Krämer B, Wolf C, Keil M, Dechent P, Binder EB, Gruber O. Investigating the Impact of a Genome-Wide Supported Bipolar Risk Variant of MAD1L1 on the Human Reward System. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 27184339 DOI: 10.1038/Npp.2016.70  0.329
2016 Kimmel M, Clive M, Gispen F, Guintivano J, Brown T, Cox O, Beckmann MW, Kornhuber J, Fasching PA, Osborne LM, Binder E, Payne JL, Kaminsky Z. Oxytocin receptor DNA methylation in postpartum depression. Psychoneuroendocrinology. 69: 150-160. PMID 27108164 DOI: 10.1016/J.Psyneuen.2016.04.008  0.389
2016 Menke A, Arloth J, Best J, Namendorf C, Gerlach T, Czamara D, Lucae S, Dunlop BW, Crowe TM, Garlow SJ, Nemeroff CB, Ritchie JC, Craighead WE, Mayberg HS, Rex-Haffner M, ... Binder EB, et al. Time-dependent effects of dexamethasone plasma concentrations on glucocorticoid receptor challenge tests. Psychoneuroendocrinology. 69: 161-171. PMID 27107207 DOI: 10.1016/j.psyneuen.2016.04.003  0.592
2016 Houtepen LC, Vinkers CH, Carrillo-Roa T, Hiemstra M, van Lier PA, Meeus W, Branje S, Heim CM, Nemeroff CB, Mill J, Schalkwyk LC, Creyghton MP, Kahn RS, Joëls M, Binder EB, et al. Genome-wide DNA methylation levels and altered cortisol stress reactivity following childhood trauma in humans. Nature Communications. 7: 10967. PMID 26997371 DOI: 10.1038/Ncomms10967  0.616
2016 Wingo AP, Almli LM, Stevens JS, Klengel T, Uddin M, Li Y, Bustamante AC, Lori A, Koen N, Stein DJ, Smith AK, Aiello AE, Koenen KC, Wildman DE, Galea S, ... ... Binder EB, et al. Corrigendum: DICER1 and microRNA regulation in post-traumatic stress disorder with comorbid depression. Nature Communications. 7: 10958. PMID 26936533 DOI: 10.1038/Ncomms10958  0.315
2016 Kao CY, He Z, Zannas AS, Hahn O, Kühne C, Reichel JM, Binder EB, Wotjak CT, Khaitovich P, Turck CW. Fluoxetine treatment prevents the inflammatory response in a mouse model of posttraumatic stress disorder. Journal of Psychiatric Research. 76: 74-83. PMID 26897419 DOI: 10.1016/J.Jpsychires.2016.02.003  0.348
2016 Iyer S, Kilaru V, Almli L, Stevens J, Jovanovic T, Conneely K, Wingo A, Smith A, Ressler K, Lori A, Ely T, Bradley B, Binder E, Koen N, Stein D. Genome-wide gene-based analysis suggests an association between Neuroligin 1 (NLGN1) and Post-traumatic Stress Disorder F1000research. 5. DOI: 10.7490/F1000Research.1112140.1  0.359
2016 Pape JC, Binder EB. The Role of Genetics and Epigenetics in the Pathogenesis of Posttraumatic Stress Disorder Psychiatric Annals. 46: 510-518. DOI: 10.3928/00485713-20160729-02  0.345
2016 Carrillo-Roa T, Dunlop B, McGrath C, Czamara D, Zaanas A, Kelley M, Nemeroff C, Craighead W, Mayberg H, Binder E. P.3.004 Neuroimaging derived polygenic scores predict outcomes to psychotherapy and medication treatments for depression European Neuropsychopharmacology. 26: S48-S49. DOI: 10.1016/S0924-977X(16)70054-X  0.35
2016 Suarez A, Lahti JMT, Girchenko P, Lahti M, Hamalainen E, Laivuori H, Kajantie E, Pesonen A, Villa PM, Reynolds RM, Czamara D, Binder EB, Raikkonen K. Maternal depression during pregnancy and epigenetic age in their newborns: The PREDO study Psychoneuroendocrinology. 71: 63-63. DOI: 10.1016/J.Psyneuen.2016.07.163  0.302
2016 Smith A, Kilaru V, Klengel T, Nishitani S, Binder E, Ressler K, Bradley B, Jovanovic T. Heritable epigenetic patterns of stress-responsive genes in traumatized children Psychoneuroendocrinology. 71: 43-43. DOI: 10.1016/J.Psyneuen.2016.07.112  0.317
2016 Toepfer P, Heim CM, Entringer S, Wadhwa PD, Provencal N, Binder EB, Buss C. A variation in the oxytocin receptor gene moderates the relationship between early maternal care in childhood and interleukin 6 (IL-6) concentrations during pregnancy Psychoneuroendocrinology. 71: 15. DOI: 10.1016/J.Psyneuen.2016.07.049  0.48
2016 Jones I, Clive M, Wilcox H, Eaton W, Eck KV, Jovanovic T, Klengel T, Bradley B, Binder E, Geuze E, Rutten B, Houtepen L, Vermetten E, Vinkers C, Ressler K, et al. Stress vulnerability and epigenetic variation of SKA2, potential causes and consequences Psychoneuroendocrinology. 71: 11-11. DOI: 10.1016/J.Psyneuen.2016.07.038  0.315
2016 Jacoby N, Overfeld J, Binder EB, Heim CM. Stress Neurobiology and Developmental Psychopathology Development and Psychopathology. 1-45. DOI: 10.1002/9781119125556.Devpsy221  0.389
2015 Zannas AS, Arloth J, Carrillo-Roa T, Iurato S, Röh S, Ressler KJ, Nemeroff CB, Smith AK, Bradley B, Heim C, Menke A, Lange JF, Brückl T, Ising M, Wray NR, ... ... Binder EB, et al. Lifetime stress accelerates epigenetic aging in an urban, African American cohort: relevance of glucocorticoid signaling. Genome Biology. 16: 266. PMID 26673150 DOI: 10.1186/s13059-015-0828-5  0.588
2015 Wingo AP, Almli LM, Stevens JJ, Klengel T, Uddin M, Li Y, Bustamante AC, Lori A, Koen N, Stein DJ, Smith AK, Aiello AE, Koenen KC, Wildman DE, Galea S, ... ... Binder EB, et al. DICER1 and microRNA regulation in post-traumatic stress disorder with comorbid depression. Nature Communications. 6: 10106. PMID 26632874 DOI: 10.1038/Ncomms10106  0.341
2015 Gassen NC, Fries GR, Zannas AS, Hartmann J, Zschocke J, Hafner K, Carrillo-Roa T, Steinbacher J, Preißinger SN, Hoeijmakers L, Knop M, Weber F, Kloiber S, Lucae S, Chrousos GP, ... ... Binder EB, et al. Chaperoning epigenetics: FKBP51 decreases the activity of DNMT1 and mediates epigenetic effects of the antidepressant paroxetine. Science Signaling. 8: ra119. PMID 26602018 DOI: 10.1126/Scisignal.Aac7695  0.349
2015 Osborne L, Clive M, Kimmel M, Gispen F, Guintivano J, Brown T, Cox O, Judy J, Meilman S, Brier A, Beckmann MW, Kornhuber J, Fasching PA, Goes F, Payne JL, ... Binder EB, et al. Replication of Epigenetic Postpartum Depression Biomarkers and Variation with Hormone Levels. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 26503311 DOI: 10.1038/Npp.2015.333  0.361
2015 Yehuda R, Daskalakis NP, Bierer LM, Bader HN, Klengel T, Holsboer F, Binder EB. Holocaust Exposure Induced Intergenerational Effects on FKBP5 Methylation. Biological Psychiatry. PMID 26410355 DOI: 10.1016/J.Biopsych.2015.08.005  0.615
2015 Kaminsky Z, Wilcox HC, Eaton WW, Van Eck K, Kilaru V, Jovanovic T, Klengel T, Bradley B, Binder EB, Ressler KJ, Smith AK. Epigenetic and genetic variation at SKA2 predict suicidal behavior and post-traumatic stress disorder. Translational Psychiatry. 5: e627. PMID 26305478 DOI: 10.1038/Tp.2015.105  0.367
2015 Zannas AS, Wiechmann T, Gassen NC, Binder EB. Gene-Stress-Epigenetic Regulation of FKBP5: Clinical and Translational Implications. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 26250598 DOI: 10.1038/npp.2015.235  0.402
2015 Feng C, Lori A, Waldman ID, Binder EB, Haroon E, Rilling JK. A common oxytocin receptor gene (OXTR) polymorphism modulates intranasal oxytocin effects on the neural response to social cooperation in humans. Genes, Brain, and Behavior. 14: 516-25. PMID 26178189 DOI: 10.1111/Gbb.12234  0.317
2015 Kohrt BA, Worthman CM, Ressler KJ, Mercer KB, Upadhaya N, Koirala S, Nepal MK, Sharma VD, Binder EB. Cross-cultural gene- environment interactions in depression, post-traumatic stress disorder, and the cortisol awakening response: FKBP5 polymorphisms and childhood trauma in South Asia. International Review of Psychiatry (Abingdon, England). 27: 180-96. PMID 26100613 DOI: 10.3109/09540261.2015.1020052  0.408
2015 Klengel T, Binder EB. Epigenetics of Stress-Related Psychiatric Disorders and Gene × Environment Interactions. Neuron. 86: 1343-57. PMID 26087162 DOI: 10.1016/j.neuron.2015.05.036  0.39
2015 Arloth J, Bogdan R, Weber P, Frishman G, Menke A, Wagner KV, Balsevich G, Schmidt MV, Karbalai N, Czamara D, Altmann A, Trümbach D, Wurst W, Mehta D, Uhr M, ... ... Binder EB, et al. Genetic Differences in the Immediate Transcriptome Response to Stress Predict Risk-Related Brain Function and Psychiatric Disorders. Neuron. 86: 1189-202. PMID 26050039 DOI: 10.1016/J.Neuron.2015.05.034  0.418
2015 Zannas AS, Provençal N, Binder EB. Epigenetics of Posttraumatic Stress Disorder: Current Evidence, Challenges, and Future Directions. Biological Psychiatry. 78: 327-35. PMID 25979620 DOI: 10.1016/j.biopsych.2015.04.003  0.386
2015 Logue MW, Smith AK, Baldwin C, Wolf EJ, Guffanti G, Ratanatharathorn A, Stone A, Schichman SA, Humphries D, Binder EB, Arloth J, Menke A, Uddin M, Wildman D, Galea S, et al. An analysis of gene expression in PTSD implicates genes involved in the glucocorticoid receptor pathway and neural responses to stress. Psychoneuroendocrinology. 57: 1-13. PMID 25867994 DOI: 10.1016/J.Psyneuen.2015.03.016  0.352
2015 Daskalakis NP, Binder EB. Schizophrenia in the spectrum of gene-stress interactions: the FKBP5 example. Schizophrenia Bulletin. 41: 323-9. PMID 25592294 DOI: 10.1093/Schbul/Sbu189  0.623
2015 Klengel T, Binder EB. FKBP5 allele-specific epigenetic modification in gene by environment interaction. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 40: 244-6. PMID 25482174 DOI: 10.1038/npp.2014.208  0.409
2015 Gaali S, Kirschner A, Cuboni S, Hartmann J, Kozany C, Balsevich G, Namendorf C, Fernandez-Vizarra P, Sippel C, Zannas AS, Draenert R, Binder EB, Almeida OF, Rühter G, Uhr M, et al. Selective inhibitors of the FK506-binding protein 51 by induced fit. Nature Chemical Biology. 11: 33-7. PMID 25436518 DOI: 10.1038/Nchembio.1699  0.318
2015 Smith AK, Kilaru V, Klengel T, Mercer KB, Bradley B, Conneely KN, Ressler KJ, Binder EB. DNA extracted from saliva for methylation studies of psychiatric traits: evidence tissue specificity and relatedness to brain. American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics. 168: 36-44. PMID 25355443 DOI: 10.1002/Ajmg.B.32278  0.304
2015 Jukic MM, Carrillo-Roa T, Bar M, Becker G, Jovanovic VM, Zega K, Binder EB, Brodski C. Abnormal development of monoaminergic neurons is implicated in mood fluctuations and bipolar disorder. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 40: 839-48. PMID 25241801 DOI: 10.1038/npp.2014.244  0.319
2015 Provencal N, Binder EB. The neurobiological effects of stress as contributors to psychiatric disorders: focus on epigenetics. Current Opinion in Neurobiology. 30: 31-7. PMID 25218938 DOI: 10.1016/j.conb.2014.08.007  0.353
2015 Provençal N, Binder EB. The effects of early life stress on the epigenome: From the womb to adulthood and even before. Experimental Neurology. 268: 10-20. PMID 25218020 DOI: 10.1016/j.expneurol.2014.09.001  0.361
2015 Zannas A, Carrillo-Roa T, Iurato S, Ressler K, Nemeroff C, Smith A, Lange J, Bradley B, Heim C, Brückl T, Ising M, Wray N, Erhardt A, Binder E, Mehta D. Lifetime Stress Accelerates Epigenetic Aging European Psychiatry. 30: 799. DOI: 10.1016/S0924-9338(15)31949-0  0.618
2014 Rampp C, Binder EB, Provençal N. Epigenetics in posttraumatic stress disorder. Progress in Molecular Biology and Translational Science. 128: 29-50. PMID 25410540 DOI: 10.1016/B978-0-12-800977-2.00002-4  0.385
2014 Almli LM, Duncan R, Feng H, Ghosh D, Binder EB, Bradley B, Ressler KJ, Conneely KN, Epstein MP. Correcting systematic inflation in genetic association tests that consider interaction effects: application to a genome-wide association study of posttraumatic stress disorder. Jama Psychiatry. 71: 1392-9. PMID 25354142 DOI: 10.1001/Jamapsychiatry.2014.1339  0.369
2014 Pape JC, Binder EB. [Psychological trauma as risk for delayed psychiatric disorders: epigenetic mechanisms]. Der Nervenarzt. 85: 1382-9. PMID 25208492 DOI: 10.1007/s00115-014-4085-8  0.335
2014 Sabbagh JJ, O'Leary JC, Blair LJ, Klengel T, Nordhues BA, Fontaine SN, Binder EB, Dickey CA. Age-associated epigenetic upregulation of the FKBP5 gene selectively impairs stress resiliency. Plos One. 9: e107241. PMID 25191701 DOI: 10.1371/journal.pone.0107241  0.395
2014 Mullins N, Perroud N, Uher R, Butler AW, Cohen-Woods S, Rivera M, Malki K, Euesden J, Power RA, Tansey KE, Jones L, Jones I, Craddock N, Owen MJ, Korszun A, ... ... Binder EB, et al. Genetic relationships between suicide attempts, suicidal ideation and major psychiatric disorders: a genome-wide association and polygenic scoring study. American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics. 165: 428-37. PMID 24964207 DOI: 10.1002/Ajmg.B.32247  0.352
2014 Issler O, Haramati S, Paul ED, Maeno H, Navon I, Zwang R, Gil S, Mayberg HS, Dunlop BW, Menke A, Awatramani R, Binder EB, Deneris ES, Lowry CA, Chen A. MicroRNA 135 is essential for chronic stress resiliency, antidepressant efficacy, and intact serotonergic activity. Neuron. 83: 344-60. PMID 24952960 DOI: 10.1016/J.Neuron.2014.05.042  0.328
2014 Dunlop BW, Rothbaum BO, Binder EB, Duncan E, Harvey PD, Jovanovic T, Kelley ME, Kinkead B, Kutner M, Iosifescu DV, Mathew SJ, Neylan TC, Kilts CD, Nemeroff CB, Mayberg HS. Evaluation of a corticotropin releasing hormone type 1 receptor antagonist in women with posttraumatic stress disorder: study protocol for a randomized controlled trial. Trials. 15: 240. PMID 24950747 DOI: 10.1186/1745-6215-15-240  0.697
2014 Labermaier C, Kohl C, Hartmann J, Devigny C, Altmann A, Weber P, Arloth J, Quast C, Wagner KV, Scharf SH, Czibere L, Widner-Andrä R, Brenndörfer J, Landgraf R, Hausch F, ... ... Binder EB, et al. A polymorphism in the Crhr1 gene determines stress vulnerability in male mice. Endocrinology. 155: 2500-10. PMID 24773341 DOI: 10.1210/En.2013-1986  0.389
2014 Menke A, Arloth J, Gerber M, Rex-Haffner M, Uhr M, Holsboer F, Binder EB, Holsboer-Trachsler E, Beck J. Dexamethasone stimulated gene expression in peripheral blood indicates glucocorticoid-receptor hypersensitivity in job-related exhaustion. Psychoneuroendocrinology. 44: 35-46. PMID 24767618 DOI: 10.1055/S-0033-1353309  0.322
2014 Schneider M, Engel A, Fasching PA, Häberle L, Binder EB, Voigt F, Grimm J, Faschingbauer F, Eichler A, Dammer U, Rebhan D, Amann M, Raabe E, Goecke TW, Quast C, et al. Genetic variants in the genes of the stress hormone signalling pathway and depressive symptoms during and after pregnancy. Biomed Research International. 2014: 469278. PMID 24741566 DOI: 10.1155/2014/469278  0.376
2014 Nemeroff CB, Binder E. The preeminent role of childhood abuse and neglect in vulnerability to major psychiatric disorders: toward elucidating the underlying neurobiological mechanisms. Journal of the American Academy of Child and Adolescent Psychiatry. 53: 395-7. PMID 24655648 DOI: 10.1016/j.jaac.2014.02.004  0.47
2014 Mehta D, Newport DJ, Frishman G, Kraus L, Rex-Haffner M, Ritchie JC, Lori A, Knight BT, Stagnaro E, Ruepp A, Stowe ZN, Binder EB. Early predictive biomarkers for postpartum depression point to a role for estrogen receptor signaling. Psychological Medicine. 44: 2309-22. PMID 24495551 DOI: 10.1017/S0033291713003231  0.67
2014 Klengel T, Pape J, Binder EB, Mehta D. The role of DNA methylation in stress-related psychiatric disorders. Neuropharmacology. 80: 115-32. PMID 24452011 DOI: 10.1016/j.neuropharm.2014.01.013  0.399
2014 Thompson PM, Stein JL, Medland SE, Hibar DP, Vasquez AA, Renteria ME, Toro R, Jahanshad N, Schumann G, Franke B, Wright MJ, Martin NG, Agartz I, Alda M, Alhusaini S, ... ... Binder EB, et al. The ENIGMA Consortium: large-scale collaborative analyses of neuroimaging and genetic data. Brain Imaging and Behavior. 8: 153-82. PMID 24399358 DOI: 10.1007/S11682-013-9269-5  0.31
2014 Fani N, King TZ, Reiser E, Binder EB, Jovanovic T, Bradley B, Ressler KJ. FKBP5 genotype and structural integrity of the posterior cingulum. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 39: 1206-13. PMID 24253961 DOI: 10.1038/Npp.2013.322  0.381
2014 Zannas AS, Binder EB. Gene-environment interactions at the FKBP5 locus: sensitive periods, mechanisms and pleiotropism. Genes, Brain, and Behavior. 13: 25-37. PMID 24219237 DOI: 10.1111/gbb.12104  0.373
2014 Ferentinos P, Rivera M, Ising M, Spain SL, Cohen-Woods S, Butler AW, Craddock N, Owen MJ, Korszun A, Jones L, Jones I, Gill M, Rice JP, Maier W, Mors O, ... ... Binder EB, et al. Investigating the genetic variation underlying episodicity in major depressive disorder: suggestive evidence for a bipolar contribution. Journal of Affective Disorders. 155: 81-9. PMID 24215895 DOI: 10.1016/J.Jad.2013.10.027  0.357
2014 Zannas A, Klengel T, Nemeroff C, Carrillo-Roa T, Heim C, Bradley B, Ressler K, Binder E. P.1.a.003 Epigenetic regulation at the FKBP5 genetic locus by age and depressive phenotypes: implications for age-related disease European Neuropsychopharmacology. 24: S154. DOI: 10.1016/S0924-977X(14)70234-2  0.364
2013 Lee SH, Ripke S, Neale BM, Faraone SV, Purcell SM, Perlis RH, Mowry BJ, Thapar A, Goddard ME, Witte JS, Absher D, Agartz I, Akil H, Amin F, ... ... Binder EB, et al. Genetic relationship between five psychiatric disorders estimated from genome-wide SNPs. Nature Genetics. 45: 984-94. PMID 23933821 DOI: 10.1038/Ng.2711  0.322
2013 Quast C, Cuboni S, Bader D, Altmann A, Weber P, Arloth J, Röh S, Brückl T, Ising M, Kopczak A, Erhardt A, Hausch F, Lucae S, Binder EB. Functional coding variants in SLC6A15, a possible risk gene for major depression. Plos One. 8: e68645. PMID 23874702 DOI: 10.1371/Journal.Pone.0068645  0.359
2013 Andero R, Brothers SP, Jovanovic T, Chen YT, Salah-Uddin H, Cameron M, Bannister TD, Almli L, Stevens JS, Bradley B, Binder EB, Wahlestedt C, Ressler KJ. Amygdala-dependent fear is regulated by Oprl1 in mice and humans with PTSD. Science Translational Medicine. 5: 188ra73. PMID 23740899 DOI: 10.1126/Scitranslmed.3005656  0.333
2013 Mehta D, Klengel T, Conneely KN, Smith AK, Altmann A, Pace TW, Rex-Haffner M, Loeschner A, Gonik M, Mercer KB, Bradley B, Müller-Myhsok B, Ressler KJ, Binder EB. Childhood maltreatment is associated with distinct genomic and epigenetic profiles in posttraumatic stress disorder. Proceedings of the National Academy of Sciences of the United States of America. 110: 8302-7. PMID 23630272 DOI: 10.1073/Pnas.1217750110  0.393
2013 Mehta D, Raison CL, Woolwine BJ, Haroon E, Binder EB, Miller AH, Felger JC. Transcriptional signatures related to glucose and lipid metabolism predict treatment response to the tumor necrosis factor antagonist infliximab in patients with treatment-resistant depression. Brain, Behavior, and Immunity. 31: 205-15. PMID 23624296 DOI: 10.1016/j.bbi.2013.04.004  0.32
2013 Norrholm SD, Jovanovic T, Smith AK, Binder E, Klengel T, Conneely K, Mercer KB, Davis JS, Kerley K, Winkler J, Gillespie CF, Bradley B, Ressler KJ. Differential Genetic and Epigenetic Regulation of catechol-O-methyltransferase is Associated with Impaired Fear Inhibition in Posttraumatic Stress Disorder. Frontiers in Behavioral Neuroscience. 7: 30. PMID 23596403 DOI: 10.3389/Fnbeh.2013.00030  0.655
2013 Klengel T, Binder EB. Allele-specific epigenetic modification: a molecular mechanism for gene-environment interactions in stress-related psychiatric disorders? Epigenomics. 5: 109-12. PMID 23566086 DOI: 10.2217/epi.13.11  0.424
2013 Gillespie CF, Almli LM, Smith AK, Bradley B, Kerley K, Crain DF, Mercer KB, Weiss T, Phifer J, Tang Y, Cubells JF, Binder EB, Conneely KN, Ressler KJ. Sex dependent influence of a functional polymorphism in steroid 5-α-reductase type 2 (SRD5A2) on post-traumatic stress symptoms. American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics. 162: 283-92. PMID 23505265 DOI: 10.1002/Ajmg.B.32147  0.654
2013 Klengel T, Binder EB. Gene-environment interactions in major depressive disorder. Canadian Journal of Psychiatry. Revue Canadienne De Psychiatrie. 58: 76-83. PMID 23442893 DOI: 10.1177/070674371305800203  0.397
2013 Fani N, Gutman D, Tone EB, Almli L, Mercer KB, Davis J, Glover E, Jovanovic T, Bradley B, Dinov ID, Zamanyan A, Toga AW, Binder EB, Ressler KJ. FKBP5 and attention bias for threat: associations with hippocampal function and shape. Jama Psychiatry. 70: 392-400. PMID 23407841 DOI: 10.1001/2013.Jamapsychiatry.210  0.574
2013 Menke A, Klengel T, Rubel J, Brückl T, Pfister H, Lucae S, Uhr M, Holsboer F, Binder EB. Genetic variation in FKBP5 associated with the extent of stress hormone dysregulation in major depression. Genes, Brain, and Behavior. 12: 289-96. PMID 23406438 DOI: 10.1111/Gbb.12026  0.389
2013 Power RA, Wingenbach T, Cohen-Woods S, Uher R, Ng MY, Butler AW, Ising M, Craddock N, Owen MJ, Korszun A, Jones L, Jones I, Gill M, Rice JP, Maier W, ... ... Binder EB, et al. Estimating the heritability of reporting stressful life events captured by common genetic variants. Psychological Medicine. 43: 1965-71. PMID 23237013 DOI: 10.1017/S0033291712002589  0.319
2013 Klengel T, Binder EB. Gene × environment interactions in the prediction of response to antidepressant treatment. The International Journal of Neuropsychopharmacology / Official Scientific Journal of the Collegium Internationale Neuropsychopharmacologicum (Cinp). 16: 701-11. PMID 23237009 DOI: 10.1017/S1461145712001459  0.366
2013 Klengel T, Mehta D, Anacker C, Rex-Haffner M, Pruessner JC, Pariante CM, Pace TW, Mercer KB, Mayberg HS, Bradley B, Nemeroff CB, Holsboer F, Heim CM, Ressler KJ, Rein T, ... Binder EB, et al. Allele-specific FKBP5 DNA demethylation mediates gene-childhood trauma interactions. Nature Neuroscience. 16: 33-41. PMID 23201972 DOI: 10.1038/Nn.3275  0.646
2013 Kloiber S, Ripke S, Kohli MA, Reppermund S, Salyakina D, Uher R, McGuffin P, Perlis RH, Hamilton SP, Pütz B, Hennings J, Brückl T, Klengel T, Bettecken T, Ising M, ... ... Binder E, et al. Resistance to antidepressant treatment is associated with polymorphisms in the leptin gene, decreased leptin mRNA expression, and decreased leptin serum levels. European Neuropsychopharmacology : the Journal of the European College of Neuropsychopharmacology. 23: 653-62. PMID 23026132 DOI: 10.1016/J.Euroneuro.2012.08.010  0.363
2013 Bourke CH, Raees MQ, Malviya S, Bradburn CA, Binder EB, Neigh GN. Glucocorticoid sensitizers Bag1 and Ppid are regulated by adolescent stress in a sex-dependent manner. Psychoneuroendocrinology. 38: 84-93. PMID 22647578 DOI: 10.1016/j.psyneuen.2012.05.001  0.706
2012 Power RA, Keers R, Ng MY, Butler AW, Uher R, Cohen-Woods S, Ising M, Craddock N, Owen MJ, Korszun A, Jones L, Jones I, Gill M, Rice JP, Hauser J, ... ... Binder EB, et al. Dissecting the genetic heterogeneity of depression through age at onset. American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics. 159: 859-68. PMID 22915352 DOI: 10.1002/Ajmg.B.32093  0.345
2012 Kennedy AP, Binder EB, Bowman D, Harenski K, Ely T, Cisler JM, Tripathi SP, VanNess S, Kilts CD. A common TPH2 haplotype regulates the neural processing of a cognitive control demand. American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics. 159: 829-40. PMID 22915309 DOI: 10.1002/Ajmg.B.32090  0.321
2012 Quast C, Altmann A, Weber P, Arloth J, Bader D, Heck A, Pfister H, Müller-Myhsok B, Erhardt A, Binder EB. Rare variants in TMEM132D in a case-control sample for panic disorder. American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics. 159: 896-907. PMID 22911938 DOI: 10.1002/ajmg.b.32096  0.325
2012 Dunlop BW, Binder EB, Cubells JF, Goodman MM, Kelley ME, Kinkead B, Kutner M, Nemeroff CB, Newport DJ, Owens MJ, Pace TW, Ritchie JC, Rivera VA, Westen D, Craighead WE, et al. Predictors of remission in depression to individual and combined treatments (PReDICT): study protocol for a randomized controlled trial. Trials. 13: 106. PMID 22776534 DOI: 10.1186/1745-6215-13-106  0.76
2012 Fasching PA, Faschingbauer F, Goecke TW, Engel A, Häberle L, Seifert A, Voigt F, Amann M, Rebhan D, Burger P, Kornhuber J, Ekici AB, Beckmann MW, Binder EB. Genetic variants in the tryptophan hydroxylase 2 gene (TPH2) and depression during and after pregnancy. Journal of Psychiatric Research. 46: 1109-17. PMID 22721547 DOI: 10.1016/J.Jpsychires.2012.05.011  0.35
2012 Menke A, Klengel T, Binder EB. Epigenetics, depression and antidepressant treatment. Current Pharmaceutical Design. 18: 5879-89. PMID 22681167 DOI: 10.2174/138161212803523590  0.387
2012 Hunter JE, Leslie M, Novak G, Hamilton D, Shubeck L, Charen K, Abramowitz A, Epstein MP, Lori A, Binder E, Cubells JF, Sherman SL. Depression and anxiety symptoms among women who carry the FMR1 premutation: impact of raising a child with fragile X syndrome is moderated by CRHR1 polymorphisms. American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics. 159: 549-59. PMID 22573456 DOI: 10.1002/ajmg.b.32061  0.38
2012 Stein JL, Medland SE, Vasquez AA, Hibar DP, Senstad RE, Winkler AM, Toro R, Appel K, Bartecek R, Bergmann Ø, Bernard M, Brown AA, Cannon DM, Chakravarty MM, Christoforou A, ... ... Binder EB, et al. Identification of common variants associated with human hippocampal and intracranial volumes. Nature Genetics. 44: 552-61. PMID 22504417 DOI: 10.1038/Ng.2250  0.308
2012 Binder EB, Holsboer F. Low cortisol and risk and resilience to stress-related psychiatric disorders. Biological Psychiatry. 71: 282-3. PMID 22265026 DOI: 10.1016/J.Biopsych.2011.12.008  0.336
2012 Menke A, Arloth J, Pütz B, Weber P, Klengel T, Mehta D, Gonik M, Rex-Haffner M, Rubel J, Uhr M, Lucae S, Deussing JM, Müller-Myhsok B, Holsboer F, Binder EB. Dexamethasone stimulated gene expression in peripheral blood is a sensitive marker for glucocorticoid receptor resistance in depressed patients. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 37: 1455-64. PMID 22237309 DOI: 10.1038/Npp.2011.331  0.35
2012 Mehta D, Quast C, Fasching PA, Seifert A, Voigt F, Beckmann MW, Faschingbauer F, Burger P, Ekici AB, Kornhuber J, Binder EB, Goecke TW. The 5-HTTLPR polymorphism modulates the influence on environmental stressors on peripartum depression symptoms. Journal of Affective Disorders. 136: 1192-7. PMID 22209125 DOI: 10.1016/J.Jad.2011.11.042  0.374
2012 Cáceda R, Binder EB, Kinkead B, Nemeroff CB. The role of endogenous neurotensin in psychostimulant-induced disruption of prepulse inhibition and locomotion. Schizophrenia Research. 136: 88-95. PMID 22104138 DOI: 10.1016/j.schres.2011.10.013  0.758
2012 Heim C, Binder EB. Current research trends in early life stress and depression: review of human studies on sensitive periods, gene-environment interactions, and epigenetics. Experimental Neurology. 233: 102-11. PMID 22101006 DOI: 10.1016/j.expneurol.2011.10.032  0.559
2012 Menke A, Domschke K, Czamara D, Klengel T, Hennings J, Lucae S, Baune BT, Arolt V, Müller-Myhsok B, Holsboer F, Binder EB. Genome-wide association study of antidepressant treatment-emergent suicidal ideation. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 37: 797-807. PMID 22030708 DOI: 10.1038/Npp.2011.257  0.329
2012 Katz ER, Stowe ZN, Newport DJ, Kelley ME, Pace TW, Cubells JF, Binder EB. Regulation of mRNA expression encoding chaperone and co-chaperone proteins of the glucocorticoid receptor in peripheral blood: association with depressive symptoms during pregnancy. Psychological Medicine. 42: 943-56. PMID 21995950 DOI: 10.1017/S0033291711002121  0.676
2012 Menke A, Sämann P, Kloiber S, Czamara D, Lucae S, Hennings J, Heck A, Kohli MA, Czisch M, Müller-Myhsok B, Holsboer F, Binder EB. Polymorphisms within the metabotropic glutamate receptor 1 gene are associated with depression phenotypes. Psychoneuroendocrinology. 37: 565-75. PMID 21962378 DOI: 10.1016/J.Psyneuen.2011.09.003  0.384
2012 Mehta D, Binder EB. Gene × environment vulnerability factors for PTSD: the HPA-axis. Neuropharmacology. 62: 654-62. PMID 21439305 DOI: 10.1016/j.neuropharm.2011.03.009  0.343
2011 Klengel T, Binder EB. Using gene-environment interactions to target personalized treatment in mood disorder. Personalized Medicine. 8: 23-34. PMID 29768787 DOI: 10.2217/pme.10.73  0.372
2011 Bradley B, Westen D, Mercer KB, Binder EB, Jovanovic T, Crain D, Wingo A, Heim C. Association between childhood maltreatment and adult emotional dysregulation in a low-income, urban, African American sample: moderation by oxytocin receptor gene. Development and Psychopathology. 23: 439-52. PMID 23786688 DOI: 10.1017/S0954579411000162  0.521
2011 Zimmermann P, Brückl T, Nocon A, Pfister H, Binder EB, Uhr M, Lieb R, Moffitt TE, Caspi A, Holsboer F, Ising M. Interaction of FKBP5 gene variants and adverse life events in predicting depression onset: results from a 10-year prospective community study. The American Journal of Psychiatry. 168: 1107-16. PMID 21865530 DOI: 10.1176/Appi.Ajp.2011.10111577  0.41
2011 Schosser A, Butler AW, Ising M, Perroud N, Uher R, Ng MY, Cohen-Woods S, Craddock N, Owen MJ, Korszun A, Jones L, Jones I, Gill M, Rice JP, Maier W, ... ... Binder EB, et al. Genomewide association scan of suicidal thoughts and behaviour in major depression. Plos One. 6: e20690. PMID 21750702 DOI: 10.1371/Journal.Pone.0020690  0.343
2011 Horstmann S, Binder EB. Glucocorticoids as predictors of treatment response in depression. Harvard Review of Psychiatry. 19: 125-43. PMID 21631159 DOI: 10.3109/10673229.2011.586550  0.382
2011 Mehta D, Gonik M, Klengel T, Rex-Haffner M, Menke A, Rubel J, Mercer KB, Pütz B, Bradley B, Holsboer F, Ressler KJ, Müller-Myhsok B, Binder EB. Using polymorphisms in FKBP5 to define biologically distinct subtypes of posttraumatic stress disorder: evidence from endocrine and gene expression studies. Archives of General Psychiatry. 68: 901-10. PMID 21536970 DOI: 10.1001/Archgenpsychiatry.2011.50  0.393
2011 Kohli MA, Lucae S, Saemann PG, Schmidt MV, Demirkan A, Hek K, Czamara D, Alexander M, Salyakina D, Ripke S, Hoehn D, Specht M, Menke A, Hennings J, Heck A, ... ... Binder EB, et al. The neuronal transporter gene SLC6A15 confers risk to major depression. Neuron. 70: 252-65. PMID 21521612 DOI: 10.1016/J.Neuron.2011.04.005  0.366
2011 Ressler KJ, Mercer KB, Bradley B, Jovanovic T, Mahan A, Kerley K, Norrholm SD, Kilaru V, Smith AK, Myers AJ, Ramirez M, Engel A, Hammack SE, Toufexis D, Braas KM, ... Binder EB, et al. Post-traumatic stress disorder is associated with PACAP and the PAC1 receptor. Nature. 470: 492-7. PMID 21350482 DOI: 10.1038/Nature09856  0.392
2011 Scharf SH, Liebl C, Binder EB, Schmidt MV, Müller MB. Expression and regulation of the Fkbp5 gene in the adult mouse brain. Plos One. 6: e16883. PMID 21347384 DOI: 10.1371/Journal.Pone.0016883  0.33
2011 Domschke K, Reif A, Weber H, Richter J, Hohoff C, Ohrmann P, Pedersen A, Bauer J, Suslow T, Kugel H, Heindel W, Baumann C, Klauke B, Jacob C, Maier W, ... ... Binder EB, et al. Neuropeptide S receptor gene -- converging evidence for a role in panic disorder. Molecular Psychiatry. 16: 938-48. PMID 20603625 DOI: 10.1038/Mp.2010.81  0.339
2011 Dunlop BW, Betancourt Y, Binder EB, Heim C, Holsboer F, Ising M, McKenzie M, Mletzko T, Pfister H, Nemeroff CB, Craighead WE, Mayberg HS. Tolerability of the dexamethasone-corticotropin releasing hormone test in major depressive disorder. Journal of Psychiatric Research. 45: 24-8. PMID 20488460 DOI: 10.1016/J.Jpsychires.2010.04.020  0.592
2011 Gillespie CF, Binder EB, Holtzheimer PE, Nemeroff CB. Stress and the Impact of Personalized Medicine Integrative Neuroscience and Personalized Medicine. DOI: 10.1093/acprof:oso/9780195393804.003.0005  0.626
2011 Pace T, Heim C, Binder E, Nemeroff C, Miller A. 159. History of childhood trauma is associated with impaired glucocorticoid sensitivity in adulthood Brain, Behavior, and Immunity. 25: S225. DOI: 10.1016/j.bbi.2011.07.162  0.433
2011 Binder E, Mehta D, Ressler K, Holsboer F. Posttraumatic stress disorder subtypes invalid - Reply Archives of General Psychiatry. 68: 978-980. DOI: 10.1001/Archgenpsychiatry.2011.94  0.327
2010 Schmidt MV, Trümbach D, Weber P, Wagner K, Scharf SH, Liebl C, Datson N, Namendorf C, Gerlach T, Kühne C, Uhr M, Deussing JM, Wurst W, Binder EB, Holsboer F, et al. Individual stress vulnerability is predicted by short-term memory and AMPA receptor subunit ratio in the hippocampus. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 30: 16949-58. PMID 21159965 DOI: 10.1523/Jneurosci.4668-10.2010  0.38
2010 Martin EI, Ressler KJ, Binder E, Nemeroff CB. The neurobiology of anxiety disorders: brain imaging, genetics, and psychoneuroendocrinology. Clinics in Laboratory Medicine. 30: 865-91. PMID 20832657 DOI: 10.1016/j.cll.2010.07.006  0.47
2010 Rietschel M, Mattheisen M, Frank J, Treutlein J, Degenhardt F, Breuer R, Steffens M, Mier D, Esslinger C, Walter H, Kirsch P, Erk S, Schnell K, Herms S, Wichmann HE, ... ... Binder EB, et al. Genome-wide association-, replication-, and neuroimaging study implicates HOMER1 in the etiology of major depression. Biological Psychiatry. 68: 578-85. PMID 20673876 DOI: 10.1016/j.biopsych.2010.05.038  0.369
2010 Mehta D, Menke A, Binder EB. Gene expression studies in major depression. Current Psychiatry Reports. 12: 135-44. PMID 20425299 DOI: 10.1007/s11920-010-0100-3  0.322
2010 Binder EB, Owens MJ, Liu W, Deveau TC, Rush AJ, Trivedi MH, Fava M, Bradley B, Ressler KJ, Nemeroff CB. Association of polymorphisms in genes regulating the corticotropin-releasing factor system with antidepressant treatment response. Archives of General Psychiatry. 67: 369-79. PMID 20368512 DOI: 10.1001/Archgenpsychiatry.2010.18  0.644
2010 Unschuld PG, Ising M, Roeske D, Erhardt A, Specht M, Kloiber S, Uhr M, Müller-Myhsok B, Holsboer F, Binder EB. Gender-specific association of galanin polymorphisms with HPA-axis dysregulation, symptom severity, and antidepressant treatment response. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 35: 1583-92. PMID 20237460 DOI: 10.1038/Npp.2010.30  0.412
2010 Kohli MA, Salyakina D, Pfennig A, Lucae S, Horstmann S, Menke A, Kloiber S, Hennings J, Bradley BB, Ressler KJ, Uhr M, Müller-Myhsok B, Holsboer F, Binder EB. Association of genetic variants in the neurotrophic receptor-encoding gene NTRK2 and a lifetime history of suicide attempts in depressed patients. Archives of General Psychiatry. 67: 348-59. PMID 20124106 DOI: 10.1001/Archgenpsychiatry.2009.201  0.379
2010 Binder EB, Newport DJ, Zach EB, Smith AK, Deveau TC, Altshuler LL, Cohen LS, Stowe ZN, Cubells JF. A serotonin transporter gene polymorphism predicts peripartum depressive symptoms in an at-risk psychiatric cohort. Journal of Psychiatric Research. 44: 640-6. PMID 20045118 DOI: 10.1016/j.jpsychires.2009.12.001  0.616
2010 Ressler KJ, Bradley B, Mercer KB, Deveau TC, Smith AK, Gillespie CF, Nemeroff CB, Cubells JF, Binder EB. Polymorphisms in CRHR1 and the serotonin transporter loci: gene x gene x environment interactions on depressive symptoms. American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics. 153: 812-24. PMID 20029939 DOI: 10.1002/Ajmg.B.31052  0.691
2010 Binder EB, Nemeroff CB. The CRF system, stress, depression and anxiety-insights from human genetic studies. Molecular Psychiatry. 15: 574-88. PMID 20010888 DOI: 10.1038/mp.2009.141  0.538
2010 Horstmann S, Lucae S, Menke A, Hennings JM, Ising M, Roeske D, Müller-Myhsok B, Holsboer F, Binder EB. Polymorphisms in GRIK4, HTR2A, and FKBP5 show interactive effects in predicting remission to antidepressant treatment. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 35: 727-40. PMID 19924111 DOI: 10.1038/Npp.2009.180  0.326
2010 Kloiber S, Kohli MA, Brueckl T, Ripke S, Ising M, Uhr M, Menke A, Unschuld PG, Horstmann S, Salyakina D, Muller-Myhsok B, Binder EB, Holsboer F, Lucae S. Variations in tryptophan hydroxylase 2 linked to decreased serotonergic activity are associated with elevated risk for metabolic syndrome in depression. Molecular Psychiatry. 15: 736-47. PMID 19125159 DOI: 10.1038/Mp.2008.142  0.378
2009 Heim C, Bradley B, Mletzko TC, Deveau TC, Musselman DL, Nemeroff CB, Ressler KJ, Binder EB. Effect of Childhood Trauma on Adult Depression and Neuroendocrine Function: Sex-Specific Moderation by CRH Receptor 1 Gene. Frontiers in Behavioral Neuroscience. 3: 41. PMID 20161813 DOI: 10.3389/neuro.08.041.2009  0.743
2009 Ising M, Lucae S, Binder EB, Bettecken T, Uhr M, Ripke S, Kohli MA, Hennings JM, Horstmann S, Kloiber S, Menke A, Bondy B, Rupprecht R, Domschke K, Baune BT, et al. A genomewide association study points to multiple loci that predict antidepressant drug treatment outcome in depression. Archives of General Psychiatry. 66: 966-75. PMID 19736353 DOI: 10.1001/Archgenpsychiatry.2009.95  0.348
2009 Martin EI, Ressler KJ, Binder E, Nemeroff CB. The neurobiology of anxiety disorders: brain imaging, genetics, and psychoneuroendocrinology. The Psychiatric Clinics of North America. 32: 549-75. PMID 19716990 DOI: 10.1016/j.psc.2009.05.004  0.47
2009 Horstmann S, Binder EB. Pharmacogenomics of antidepressant drugs. Pharmacology & Therapeutics. 124: 57-73. PMID 19563827 DOI: 10.1016/j.pharmthera.2009.06.007  0.355
2009 Binder EB. The role of FKBP5, a co-chaperone of the glucocorticoid receptor in the pathogenesis and therapy of affective and anxiety disorders. Psychoneuroendocrinology. 34: S186-95. PMID 19560279 DOI: 10.1016/j.psyneuen.2009.05.021  0.404
2009 Unschuld PG, Ising M, Specht M, Erhardt A, Ripke S, Heck A, Kloiber S, Straub V, Brueckl T, Müller-Myhsok B, Holsboer F, Binder EB. Polymorphisms in the GAD2 gene-region are associated with susceptibility for unipolar depression and with a risk factor for anxiety disorders. American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics. 150: 1100-9. PMID 19229853 DOI: 10.1002/Ajmg.B.30938  0.366
2009 Hennings JM, Owashi T, Binder EB, Horstmann S, Menke A, Kloiber S, Dose T, Wollweber B, Spieler D, Messer T, Lutz R, Künzel H, Bierner T, Pollmächer T, Pfister H, et al. Clinical characteristics and treatment outcome in a representative sample of depressed inpatients - findings from the Munich Antidepressant Response Signature (MARS) project. Journal of Psychiatric Research. 43: 215-29. PMID 18586274 DOI: 10.1016/J.Jpsychires.2008.05.002  0.338
2008 Keck ME, Kern N, Erhardt A, Unschuld PG, Ising M, Salyakina D, Müller MB, Knorr CC, Lieb R, Hohoff C, Krakowitzky P, Maier W, Bandelow B, Fritze J, Deckert J, ... ... Binder EB, et al. Combined effects of exonic polymorphisms in CRHR1 and AVPR1B genes in a case/control study for panic disorder. American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics. 147: 1196-204. PMID 18384079 DOI: 10.1002/Ajmg.B.30750  0.338
2008 Binder EB, Bradley RG, Liu W, Epstein MP, Deveau TC, Mercer KB, Tang Y, Gillespie CF, Heim CM, Nemeroff CB, Schwartz AC, Cubells JF, Ressler KJ. Association of FKBP5 polymorphisms and childhood abuse with risk of posttraumatic stress disorder symptoms in adults. Jama. 299: 1291-305. PMID 18349090 DOI: 10.1001/Jama.299.11.1291  0.741
2008 Bradley RG, Binder EB, Epstein MP, Tang Y, Nair HP, Liu W, Gillespie CF, Berg T, Evces M, Newport DJ, Stowe ZN, Heim CM, Nemeroff CB, Schwartz A, Cubells JF, et al. Influence of child abuse on adult depression: moderation by the corticotropin-releasing hormone receptor gene. Archives of General Psychiatry. 65: 190-200. PMID 18250257 DOI: 10.1001/Archgenpsychiatry.2007.26  0.796
2008 Uhr M, Tontsch A, Namendorf C, Ripke S, Lucae S, Ising M, Dose T, Ebinger M, Rosenhagen M, Kohli M, Kloiber S, Salyakina D, Bettecken T, Specht M, Pütz B, ... Binder EB, et al. Polymorphisms in the drug transporter gene ABCB1 predict antidepressant treatment response in depression. Neuron. 57: 203-9. PMID 18215618 DOI: 10.1016/J.Neuron.2007.11.017  0.333
2008 Unschuld PG, Ising M, Erhardt A, Lucae S, Kohli M, Kloiber S, Salyakina D, Thoeringer CK, Kern N, Lieb R, Uhr M, Binder EB, Müller-Myhsok B, Holsboer F, Keck ME. Polymorphisms in the galanin gene are associated with symptom-severity in female patients suffering from panic disorder. Journal of Affective Disorders. 105: 177-84. PMID 17573119 DOI: 10.1016/J.Jad.2007.05.006  0.382
2007 Himmerich H, Zimmermann P, Ising M, Kloiber S, Lucae S, Kunzel HE, Binder EB, Holsboer F, Uhr M. Changes in the hypothalamic-pituitary-adrenal axis and leptin levels during antidepressant treatment. Neuropsychobiology. 55: 28-35. PMID 17556850 DOI: 10.1159/000103573  0.323
2007 Unschuld PG, Ising M, Erhardt A, Lucae S, Kloiber S, Kohli M, Salyakina D, Welt T, Kern N, Lieb R, Uhr M, Binder EB, Müller-Myhsok B, Holsboer F, Keck ME. Polymorphisms in the serotonin receptor gene HTR2A are associated with quantitative traits in panic disorder. American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics. 144: 424-9. PMID 17440930 DOI: 10.1002/Ajmg.B.30412  0.314
2007 Erhardt A, Lucae S, Unschuld PG, Ising M, Kern N, Salyakina D, Lieb R, Uhr M, Binder EB, Keck ME, Müller-Myhsok B, Holsboer F. Association of polymorphisms in P2RX7 and CaMKKb with anxiety disorders. Journal of Affective Disorders. 101: 159-68. PMID 17197037 DOI: 10.1016/J.Jad.2006.11.016  0.369
2007 Ising M, Horstmann S, Kloiber S, Lucae S, Binder EB, Kern N, Künzel HE, Pfennig A, Uhr M, Holsboer F. Combined dexamethasone/corticotropin releasing hormone test predicts treatment response in major depression - a potential biomarker? Biological Psychiatry. 62: 47-54. PMID 17123470 DOI: 10.1016/J.Biopsych.2006.07.039  0.341
2007 Thoeringer CK, Binder EB, Salyakina D, Erhardt A, Ising M, Unschuld PG, Kern N, Lucae S, Brueckl TM, Mueller MB, Fuchs B, Puetz B, Lieb R, Uhr M, Holsboer F, et al. Association of a Met88Val diazepam binding inhibitor (DBI) gene polymorphism and anxiety disorders with panic attacks. Journal of Psychiatric Research. 41: 579-84. PMID 16904689 DOI: 10.1016/J.Jpsychires.2006.06.001  0.349
2006 Binder EB, Nemeroff CB. Implications for the practice of psychiatry. Progress in Brain Research. 158: 275-93. PMID 17027701 DOI: 10.1016/S0079-6123(06)58013-6  0.466
2006 Erhardt A, Ising M, Unschuld PG, Kern N, Lucae S, Pütz B, Uhr M, Binder EB, Holsboer F, Keck ME. Regulation of the hypothalamic-pituitary-adrenocortical system in patients with panic disorder. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 31: 2515-22. PMID 16841071 DOI: 10.1038/Sj.Npp.1301168  0.362
2006 Lucae S, Salyakina D, Barden N, Harvey M, Gagné B, Labbé M, Binder EB, Uhr M, Paez-Pereda M, Sillaber I, Ising M, Brückl T, Lieb R, Holsboer F, Müller-Myhsok B. P2RX7, a gene coding for a purinergic ligand-gated ion channel, is associated with major depressive disorder. Human Molecular Genetics. 15: 2438-45. PMID 16822851 DOI: 10.1093/Hmg/Ddl166  0.355
2006 Binder EB, Holsboer F. Pharmacogenomics and antidepressant drugs. Annals of Medicine. 38: 82-94. PMID 16581694 DOI: 10.1080/07853890600551045  0.34
2006 van Rossum EF, Binder EB, Majer M, Koper JW, Ising M, Modell S, Salyakina D, Lamberts SW, Holsboer F. Polymorphisms of the glucocorticoid receptor gene and major depression. Biological Psychiatry. 59: 681-8. PMID 16580345 DOI: 10.1016/J.Biopsych.2006.02.007  0.372
2005 Schumacher J, Jamra RA, Becker T, Ohlraun S, Klopp N, Binder EB, Schulze TG, Deschner M, Schmäl C, Höfels S, Zobel A, Illig T, Propping P, Holsboer F, Rietschel M, et al. Evidence for a relationship between genetic variants at the brain-derived neurotrophic factor (BDNF) locus and major depression. Biological Psychiatry. 58: 307-14. PMID 16005437 DOI: 10.1016/J.Biopsych.2005.04.006  0.366
2005 Ising M, Künzel HE, Binder EB, Nickel T, Modell S, Holsboer F. The combined dexamethasone/CRH test as a potential surrogate marker in depression. Progress in Neuro-Psychopharmacology & Biological Psychiatry. 29: 1085-93. PMID 15950349 DOI: 10.1016/J.Pnpbp.2005.03.014  0.35
2005 Pfennig A, Kunzel HE, Kern N, Ising M, Majer M, Fuchs B, Ernst G, Holsboer F, Binder EB. Hypothalamus-pituitary-adrenal system regulation and suicidal behavior in depression. Biological Psychiatry. 57: 336-42. PMID 15705348 DOI: 10.1016/J.Biopsych.2004.11.017  0.313
2005 Post A, Ohl F, Almeida OF, Binder EB, Rücker M, Welt S, Binder E, Holsboer F, Sillaber I. Identification of molecules potentially involved in mediating the in vivo actions of the corticotropin-releasing hormone receptor 1 antagonist, NBI30775 (R121919). Psychopharmacology. 180: 150-8. PMID 15682302 DOI: 10.1007/S00213-004-2134-X  0.322
2004 Binder EB, Salyakina D, Lichtner P, Wochnik GM, Ising M, Pütz B, Papiol S, Seaman S, Lucae S, Kohli MA, Nickel T, Künzel HE, Fuchs B, Majer M, Pfennig A, et al. Polymorphisms in FKBP5 are associated with increased recurrence of depressive episodes and rapid response to antidepressant treatment. Nature Genetics. 36: 1319-25. PMID 15565110 DOI: 10.1038/Ng1479  0.384
2004 Binder EB, Kinkead B, Owens MJ, Nemeroff CB. Neurotensin receptor antagonist SR 142948A alters Fos expression and extrapyramidal side effect profile of typical and atypical antipsychotic drugs. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 29: 2200-7. PMID 15328528 DOI: 10.1038/sj.npp.1300546  0.719
2003 Müller MB, Keck ME, Binder EB, Kresse AE, Hagemeyer TP, Landgraf R, Holsboer F, Uhr M. ABCB1 (MDR1)-type P-glycoproteins at the blood-brain barrier modulate the activity of the hypothalamic-pituitary-adrenocortical system: implications for affective disorder. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 28: 1991-9. PMID 12888779 DOI: 10.1038/Sj.Npp.1300257  0.328
2002 Binder EB, Gross RE, Nemeroff CB, Kilts CD. Effects of neurotensin receptor antagonism on latent inhibition in Sprague-Dawley rats. Psychopharmacology. 161: 288-95. PMID 12021832 DOI: 10.1007/s00213-002-1031-4  0.435
2001 Binder EB, Kinkead B, Owens MJ, Nemeroff CB. The role of neurotensin in the pathophysiology of schizophrenia and the mechanism of action of antipsychotic drugs. Biological Psychiatry. 50: 856-72. PMID 11743941 DOI: 10.1016/S0006-3223(01)01211-2  0.713
2001 Binder EB, Kinkead B, Owens MJ, Nemeroff CB. Neurotensin and dopamine interactions. Pharmacological Reviews. 53: 453-86. PMID 11734615  0.694
2001 Binder EB, Kinkead B, Owens MJ, Kilts CD, Nemeroff CB. Enhanced neurotensin neurotransmission is involved in the clinically relevant behavioral effects of antipsychotic drugs: evidence from animal models of sensorimotor gating. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 21: 601-8. PMID 11160439 DOI: 10.1523/Jneurosci.21-02-00601.2001  0.716
1999 Kinkead B, Binder EB, Nemeroff CB. Does neurotensin mediate the effects of antipsychotic drugs? Biological Psychiatry. 46: 340-51. PMID 10435199 DOI: 10.1016/S0006-3223(99)00070-0  0.668
Low-probability matches (unlikely to be authored by this person)
2018 Cruceanu C, Roeh S, Wehner S, Martinelli S, Koedel M, Giaimo RD, Cappello S, Binder E. Investigation of Prenatal Stress in the Cerebral Organoid Model: A Focus on Cell-Type Specific Responses Following Glucocorticoid Exposure Biological Psychiatry. 83. DOI: 10.1016/J.Biopsych.2018.02.211  0.3
2012 Reif A, Weber H, Domschke K, Klauke B, Baumann C, Jacob CP, Ströhle A, Gerlach AL, Alpers GW, Pauli P, Hamm A, Kircher T, Arolt V, Wittchen HU, Binder EB, et al. Meta-analysis argues for a female-specific role of MAOA-uVNTR in panic disorder in four European populations. American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics. 159: 786-93. PMID 22911667 DOI: 10.1002/Ajmg.B.32085  0.299
2005 Brunner J, Bronisch T, Uhr M, Ising M, Binder E, Holsboer F, Turck CW. Proteomic analysis of the CSF in unmedicated patients with major depressive disorder reveals alterations in suicide attempters. European Archives of Psychiatry and Clinical Neuroscience. 255: 438-40. PMID 16382377 DOI: 10.1007/S00406-005-0575-9  0.299
2017 Iurato S, Carrillo-Roa T, Arloth J, Czamara D, Ising M, Lucae S, Müller-Myhsok B, Binder E, Erhardt A. Sex-Specific Dna Methylation Signatures In Panic Disorder European Neuropsychopharmacology. 27. DOI: 10.1016/J.Euroneuro.2016.09.512  0.299
2019 Martins J, Czamara D, Lange J, Dethloff F, Binder EB, Turck CW, Erhardt A. Exposure-induced changes of plasma metabolome and gene expression in patients with panic disorder. Depression and Anxiety. PMID 31374578 DOI: 10.1002/da.22946  0.299
2017 Elbau I, Bruecklmeier B, Czisch M, Arloth J, Czamara D, Uhr M, Eidner I, Binder E, Saemann PG. 566. Acute Psychosocial Stress Impacts the Hemodynamic Response latency: A Novel Brain Phenotype that Relates to Markers of Acute and Chronic Stress Biological Psychiatry. 81. DOI: 10.1016/J.Biopsych.2017.02.436  0.298
2015 Peters MJ, Joehanes R, Pilling LC, Schurmann C, Conneely KN, Powell J, Reinmaa E, Sutphin GL, Zhernakova A, Schramm K, Wilson YA, Kobes S, Tukiainen T, Ramos YF, ... ... Binder EB, et al. The transcriptional landscape of age in human peripheral blood. Nature Communications. 6: 8570. PMID 26490707 DOI: 10.1038/Ncomms9570  0.297
2020 Merid SK, Novoloaca A, Sharp GC, Küpers LK, Kho AT, Roy R, Gao L, Annesi-Maesano I, Jain P, Plusquin M, Kogevinas M, Allard C, Vehmeijer FO, Kazmi N, Salas LA, ... ... Binder EB, et al. Epigenome-wide meta-analysis of blood DNA methylation in newborns and children identifies numerous loci related to gestational age. Genome Medicine. 12: 25. PMID 32114984 DOI: 10.1186/S13073-020-0716-9  0.296
2019 McEwen LM, O'Donnell KJ, McGill MG, Edgar RD, Jones MJ, MacIsaac JL, Lin DTS, Ramadori K, Morin A, Gladish N, Garg E, Unternaehrer E, Pokhvisneva I, Karnani N, Kee MZL, ... ... Binder EB, et al. The PedBE clock accurately estimates DNA methylation age in pediatric buccal cells. Proceedings of the National Academy of Sciences of the United States of America. PMID 31611402 DOI: 10.1073/Pnas.1820843116  0.295
2018 Halldorsdottir T, Piechaczek C, Pehl V, Wagenbuechler P, Greimel E, Matos APSd, Feldmann L, Quickenstedt-Reinhardt P, Allgaier A, Czamara D, Rex-Haffner M, Arnarson EO, Craighead E, Schulte-Koerne G, Binder E. F63. Polygenic Risk: Predicting Depressive Symptoms in Clinical and Epidemiological Cohorts of Adolescents Biological Psychiatry. 83. DOI: 10.1016/J.Biopsych.2018.02.676  0.294
2008 Menke A, Lucae S, Kloiber S, Horstmann S, Bettecken T, Uhr M, Ripke S, Ising M, Müller-Myhsok B, Holsboer F, Binder EB. Genetic markers within glutamate receptors associated with antidepressant treatment-emergent suicidal ideation. The American Journal of Psychiatry. 165: 917-8. PMID 18593792 DOI: 10.1176/Appi.Ajp.2008.08020274  0.293
2016 Andlauer TF, Buck D, Antony G, Bayas A, Bechmann L, Berthele A, Chan A, Gasperi C, Gold R, Graetz C, Haas J, Hecker M, Infante-Duarte C, Knop M, Kümpfel T, ... ... Binder EB, et al. Novel multiple sclerosis susceptibility loci implicated in epigenetic regulation. Science Advances. 2: e1501678. PMID 27386562 DOI: 10.1126/Sciadv.1501678  0.292
2020 Binder EB. Understanding the mechanisms of treatment response in depression, focus on electro-convulsive therapy. European Archives of Psychiatry and Clinical Neuroscience. 270: 789-791. PMID 32865635 DOI: 10.1007/s00406-020-01184-1  0.29
2018 Czamara D, Girchenko P, Figueiredo AS, Lahti J, Räikkönen K, Binder E. 16.4 EFFECT OF GENOTYPE AND EARLY ADVERSITY ENVIRONMENT ON DNA METHYLATION Schizophrenia Bulletin. 44: S26-S27. DOI: 10.1093/schbul/sby014.063  0.288
2020 Yeung EH, Guan W, Zeng X, Salas LA, Mumford SL, de Prado Bert P, van Meel ER, Malmberg A, Sunyer J, Duijts L, Felix JF, Czamara D, Hämäläinen E, Binder EB, Räikkönen K, et al. Cord blood DNA methylation reflects cord blood C-reactive protein levels but not maternal levels: a longitudinal study and meta-analysis. Clinical Epigenetics. 12: 60. PMID 32354366 DOI: 10.1186/S13148-020-00852-2  0.287
2014 Barfield RT, Almli LM, Kilaru V, Smith AK, Mercer KB, Duncan R, Klengel T, Mehta D, Binder EB, Epstein MP, Ressler KJ, Conneely KN. Accounting for population stratification in DNA methylation studies. Genetic Epidemiology. 38: 231-41. PMID 24478250 DOI: 10.1002/Gepi.21789  0.285
2014 Jukic M, Carrilo-Roa T, Bar M, Becker G, Jovanovic V, Zega K, Binder EB, Brodski C. Poster sessionsP.2.c. Mood disorders and treatment – Bipolar disorders (basic)P.2.c.003 Aberrant development of monoaminergic neurons is implicated in mood fluctuations and bipolar disorder European Neuropsychopharmacology. 24. DOI: 10.1016/S0924-977X(14)70652-2  0.283
2019 Clayton DF, Anreiter I, Aristizabal M, Frankland PW, Binder EB, Citri A. The role of the genome in experience-dependent plasticity: Extending the analogy of the genomic action potential. Proceedings of the National Academy of Sciences of the United States of America. PMID 31127037 DOI: 10.1073/Pnas.1820837116  0.282
2020 Alic L, Papac-Milicevic N, Czamara D, Rudnick RB, Ozsvar-Kozma M, Hartmann A, Gurbisz M, Hoermann G, Haslinger-Hutter S, Zipfel PF, Skerka C, Binder EB, Binder CJ. A genome-wide association study identifies key modulators of complement factor H binding to malondialdehyde-epitopes. Proceedings of the National Academy of Sciences of the United States of America. PMID 32321835 DOI: 10.1073/Pnas.1913970117  0.281
2019 Toepfer P, Pokhvisneva I, Garg E, Entringer S, Heim CM, Kobor MS, Provencal N, Binder EB, Wadhwa PD, Meaney MJ, Buss C, ÓDonnell KJ. Maternal prenatal depression and infant DNA methylome maturation: Developmental regulation of DNA methylation and relevance for infant behavior Psychoneuroendocrinology. 107: 80-81. DOI: 10.1016/J.Psyneuen.2019.07.231  0.279
2012 Binder EB, Ressler KJ. Emerging methods in the molecular biology of neuropsychiatric disorders. Handbook of Clinical Neurology. 106: 191-209. PMID 22608622 DOI: 10.1016/B978-0-444-52002-9.00011-5  0.279
2016 Wingo AP, Almli LM, Stevens JS, Jovanovic T, Wingo TS, Tharp G, Li Y, Lori A, Briscione M, Jin P, Binder EB, Bradley B, Gibson G, Ressler KJ. Genome-wide association study of positive emotion identifies a genetic variant and a role for microRNAs. Molecular Psychiatry. PMID 27595594 DOI: 10.1038/Mp.2016.143  0.279
2017 Schumacher J, Forstner AJ, Wolf C, Maron E, Erhardt A, Eriksson E, Hovatta I, Lavebratt C, Allgulander C, Woldbye DPD, Mors O, Ripke S, Binder E, Ruck C, Deckert J. Genome-wide association study of panic disorder European Neuropsychopharmacology. 27. DOI: 10.1016/J.Euroneuro.2016.09.605  0.278
2009 Zimmermann P, Brückl T, Pfister H, Lieb R, Wittchen H, Holsboer F, Ising M, Binder E, Uhr M, Nocon A. The interplay of variations in the FKBP5 gene and adverse life events in predicting the first onset of depression during a ten-year follow-up Pharmacopsychiatry. 42. DOI: 10.1055/S-0029-1240261  0.278
2009 Bull S, Heuzo-Diaz P, Binder E, Cubells J, Ranjith G, Maddock C, Hotopf M, Norris S, Cassidy E, Aitchison K, Cleare A, Miller A, Pariante C. 16. IL-10 genetic variants and hepatitis C patients’ symptoms of depression and fatigue before and during Interferon-alpha treatment Brain, Behavior, and Immunity. 23: S29. DOI: 10.1016/J.Bbi.2009.06.021  0.276
2014 Skuse DH, Lori A, Cubells JF, Lee I, Conneely KN, Puura K, Lehtimäki T, Binder EB, Young LJ. Common polymorphism in the oxytocin receptor gene (OXTR) is associated with human social recognition skills. Proceedings of the National Academy of Sciences of the United States of America. 111: 1987-92. PMID 24367110 DOI: 10.1073/Pnas.1302985111  0.275
2017 Girchenko P, Lahti J, Czamara D, Knight AK, Jones MJ, Suarez A, Hämäläinen E, Kajantie E, Laivuori H, Villa PM, Reynolds RM, Kobor MS, Smith AK, Binder EB, Räikkönen K. Associations between maternal risk factors of adverse pregnancy and birth outcomes and the offspring epigenetic clock of gestational age at birth. Clinical Epigenetics. 9: 49. PMID 28503212 DOI: 10.1186/S13148-017-0349-Z  0.275
2014 Menke A, Binder EB. Epigenetic alterations in depression and antidepressant treatment. Dialogues in Clinical Neuroscience. 16: 395-404. PMID 25364288  0.274
2019 Howe CG, Cox B, Fore R, Jungius J, Kvist T, Lent S, Miles HE, Salas LA, Rifas-Shiman S, Starling AP, Yousefi P, Ladd-Acosta C, Baccarelli A, Binder EB, Chatzi VL, et al. Maternal Gestational Diabetes Mellitus and Newborn DNA Methylation: Findings From the Pregnancy and Childhood Epigenetics Consortium. Diabetes Care. PMID 31601636 DOI: 10.2337/Dc19-0524  0.274
2018 Matosin N, Martinelli S, Cruceanu C, Turecki G, Binder E. 69. The Postmortem Human Brain to Characterize Novel Drug Targets for Psychiatric Disorders: Using FKBP5 as an Example Biological Psychiatry. 83. DOI: 10.1016/J.Biopsych.2018.02.086  0.274
2016 Garn H, Bahn S, Baune BT, Binder EB, Bisgaard H, Chatila TA, Chavakis T, Culmsee C, Dannlowski U, Gay S, Gern J, Haahtela T, Kircher T, Müller-Ladner U, Neurath MF, et al. Current concepts in chronic inflammatory diseases: Interactions between microbes, cellular metabolism, and inflammation. The Journal of Allergy and Clinical Immunology. 138: 47-56. PMID 27373325 DOI: 10.1016/J.Jaci.2016.02.046  0.273
2018 Martinelli S, Park D, Hafner H, Nagaraj N, Binder E, Gassen NC. Unraveling the Effect of Physiological Stress on Chaperone Mediated Autophagy-Dependent Synaptic Proteostasis Biological Psychiatry. 83. DOI: 10.1016/J.Biopsych.2018.02.517  0.272
2016 He Q, Cai T, Liu Y, Zhao N, Harmon QE, Almli LM, Binder EB, Engel SM, Ressler KJ, Conneely KN, Lin X, Wu MC. Prioritizing individual genetic variants after kernel machine testing using variable selection. Genetic Epidemiology. PMID 27488097 DOI: 10.1002/Gepi.21993  0.271
2015 Hommers L, Raab A, Bohl A, Weber H, Scholz CJ, Erhardt A, Binder E, Arolt V, Gerlach A, Gloster A, Kalisch R, Kircher T, Lonsdorf T, Ströhle A, Zwanzger P, et al. MicroRNA hsa-miR-4717-5p regulates RGS2 and may be a risk factor for anxiety-related traits. American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics. 168: 296-306. PMID 25847876 DOI: 10.1002/Ajmg.B.32312  0.27
2018 Provencal N, Arloth J, Cattaneo A, Anacker C, Klengel T, Pariante CM, Binder E. 125. Hippocampal Progenitor Cell Models in Deciphering the Epigenomics of Stress Biological Psychiatry. 83. DOI: 10.1016/J.Biopsych.2018.02.143  0.27
2017 Karlsson Linnér R, Marioni RE, Rietveld CA, Simpkin AJ, Davies NM, Watanabe K, Armstrong NJ, Auro K, Baumbach C, Bonder MJ, Buchwald J, Fiorito G, Ismail K, Iurato S, Joensuu A, ... ... Binder EB, et al. An epigenome-wide association study meta-analysis of educational attainment. Molecular Psychiatry. PMID 29086770 DOI: 10.1038/Mp.2017.210  0.27
2014 Schumann G, Binder EB, Holte A, de Kloet ER, Oedegaard KJ, Robbins TW, Walker-Tilley TR, Bitter I, Brown VJ, Buitelaar J, Ciccocioppo R, Cools R, Escera C, Fleischhacker W, Flor H, et al. Stratified medicine for mental disorders. European Neuropsychopharmacology : the Journal of the European College of Neuropsychopharmacology. 24: 5-50. PMID 24176673 DOI: 10.1016/J.Euroneuro.2013.09.010  0.268
2016 Ligthart S, Marzi C, Aslibekyan S, Mendelson MM, Conneely KN, Tanaka T, Colicino E, Waite LL, Joehanes R, Guan W, Brody JA, Elks C, Marioni R, Jhun MA, Agha G, ... ... Binder EB, et al. DNA methylation signatures of chronic low-grade inflammation are associated with complex diseases. Genome Biology. 17: 255. PMID 27955697 DOI: 10.1186/S13059-016-1119-5  0.268
2012 Menke A, Rex-Haffner M, Klengel T, Binder EB, Mehta D. Peripheral blood gene expression: it all boils down to the RNA collection tubes. Bmc Research Notes. 5: 1. PMID 22214347 DOI: 10.1186/1756-0500-5-1  0.268
2019 Elbau IG, Binder EB, Spoormaker VI. Symptoms are not the solution but the problem: Why psychiatric research should focus on processes rather than symptoms. The Behavioral and Brain Sciences. 42: e7. PMID 30940272 DOI: 10.1017/S0140525X18001000  0.266
2017 Suarez A, Lahti J, Czamara D, Lahti M, Knight AK, Girchenko P, Hämäläinen E, Kajantie E, Laivuori H, Villa PM, Reynolds RM, Smith AK, Binder EB, Räikkönen K. Epigenetic clock at birth and psychiatric problems during early childhood Psychoneuroendocrinology. 83: 52-52. DOI: 10.1016/J.Psyneuen.2017.07.381  0.265
2018 Suarez A, Lahti J, Czamara D, Lahti-Pulkkinen M, Girchenko P, Andersson S, Strandberg TE, Reynolds RM, Kajantie E, Binder EB, Raikkonen K. The epigenetic clock and pubertal, neuroendocrine, psychiatric, and cognitive outcomes in adolescents. Clinical Epigenetics. 10: 96. PMID 30021623 DOI: 10.1186/s13148-018-0528-6  0.264
2006 Himmerich H, Binder EB, Künzel HE, Schuld A, Lucae S, Uhr M, Pollmächer T, Holsboer F, Ising M. Successful antidepressant therapy restores the disturbed interplay between TNF-alpha system and HPA axis. Biological Psychiatry. 60: 882-8. PMID 16989778 DOI: 10.1016/J.Biopsych.2006.03.075  0.264
2017 Matosin N, Cruceanu C, Binder EB. Preclinical and Clinical Evidence of DNA Methylation Changes in Response to Trauma and Chronic Stress. Chronic Stress (Thousand Oaks, Calif.). 1. PMID 29503977 DOI: 10.1177/2470547017710764  0.264
2019 Witt S, Frank J, Kranaster L, Streit F, Foo J, Treutlein J, Sirignano L, Arloth J, Binder E, Sartorius A, Rietschel M. S54Epigenome-Wide Dna Methylation Profiles Pre- And Post Ect European Neuropsychopharmacology. 29. DOI: 10.1016/J.Euroneuro.2019.08.055  0.262
2015 Kohrt BA, Worthman CM, Ressler KJ, Mercer KB, Upadhaya N, Koirala S, Nepal MK, Sharma VD, Binder EB. Cross-cultural gene-environment interactions in depression, post-traumatic stress disorder, and the cortisol awakening response: FKBP5 polymorphisms and childhood trauma in South Asia: GxE interactions in South Asia International Review of Psychiatry. 27: 180-196. DOI: 10.3109/09540261.2015.1020052  0.261
2017 Moog NK, Entringer S, Styner M, O’Donnell KJ, Gilmore JH, Meaney MJ, Binder EB, Heim CM, Wadhwa PD, Buss C. Interaction between maternal cortisol in pregnancy and infant FKBP5 genotype on newborn hippocampal volume and infant stress reactivity at 12 months Psychoneuroendocrinology. 83: 26. DOI: 10.1016/J.Psyneuen.2017.07.308  0.26
2021 Richter A, Al-Bayati M, Paraskevopoulou F, Krämer B, Pruessner JC, Binder EB, Gruber O. Interaction of variant rs3800373 and city living alters the neural stress response in the anterior cingulate cortex. Stress (Amsterdam, Netherlands). 1-9. PMID 33541187 DOI: 10.1080/10253890.2020.1855420  0.259
2009 Unschuld P, Ising M, Roeske D, Erhardt A, Specht M, Ripke S, Uhr M, Kloiber S, Müller-Myhsok B, Holsboer F, Binder E. Polymorphisms in the gene encoding the neuropeptide galanin are associated with HPA-axis dysregulation and symptome severity in major-depressive- and anxiety-disorder patients Pharmacopsychiatry. 42. DOI: 10.1055/S-0029-1240238  0.258
2016 Jukić MM, Opel N, Ström J, Carrillo-Roa T, Miksys S, Novalen M, Renblom A, Sim SC, Peñas-Lledó EM, Courtet P, Llerena A, Baune BT, de Quervain DJ, Papassotiropoulos A, Tyndale RF, ... Binder EB, et al. Elevated CYP2C19 expression is associated with depressive symptoms and hippocampal homeostasis impairment. Molecular Psychiatry. PMID 27895323 DOI: 10.1038/Mp.2016.204  0.258
2012 Altmann A, Weber P, Bader D, Preuss M, Binder EB, Müller-Myhsok B. A beginners guide to SNP calling from high-throughput DNA-sequencing data. Human Genetics. 131: 1541-54. PMID 22886560 DOI: 10.1007/s00439-012-1213-z  0.257
2015 Stephan KE, Bach DR, Fletcher PC, Flint J, Frank MJ, Friston KJ, Heinz A, Huys QJ, Owen MJ, Binder EB, Dayan P, Johnstone EC, Meyer-Lindenberg A, Montague PR, Schnyder U, et al. Charting the landscape of priority problems in psychiatry, part 1: classification and diagnosis. The Lancet. Psychiatry. PMID 26573970 DOI: 10.1016/S2215-0366(15)00361-2  0.255
2021 Moore SR, Halldorsdottir T, Martins J, Lucae S, Müller-Myhsok B, Müller NS, Piechaczek C, Feldmann L, Freisleder FJ, Greimel E, Schulte-Körne G, Binder EB, Arloth J. Sex differences in the genetic regulation of the blood transcriptome response to glucocorticoid receptor activation. Translational Psychiatry. 11: 632. PMID 34903727 DOI: 10.1038/s41398-021-01756-2  0.254
2019 Breen M, Tylee D, Maihofer A, Tsuang M, Chandler S, Mehta D, Binder E, Hess J, Baker D, Risbrough V, Nievergelt C, Buxbaum J, Glatt S. PTSD BLOOD TRANSCRIPTOME MEGA-ANALYSIS: INFLAMMATORY PATHWAYS ACROSS BIOLOGICAL SEX AND MODES OF TRAUMA European Neuropsychopharmacology. 29: S1056-S1057. DOI: 10.1016/J.Euroneuro.2018.07.073  0.253
2015 Stephan KE, Binder EB, Breakspear M, Dayan P, Johnstone EC, Meyer-Lindenberg A, Schnyder U, Wang XJ, Bach DR, Fletcher PC, Flint J, Frank MJ, Heinz A, Huys QJ, Montague PR, et al. Charting the landscape of priority problems in psychiatry, part 2: pathogenesis and aetiology. The Lancet. Psychiatry. PMID 26573969 DOI: 10.1016/S2215-0366(15)00360-0  0.253
2012 Ganea K, Menke A, Schmidt MV, Lucae S, Rammes G, Liebl C, Harbich D, Sterlemann V, Storch C, Uhr M, Holsboer F, Binder EB, Sillaber I, Müller MB. Convergent animal and human evidence suggests the activin/inhibin pathway to be involved in antidepressant response. Translational Psychiatry. 2: e177. PMID 23092981 DOI: 10.1038/Tp.2012.104  0.251
2005 Unschuld P, Ising M, Erhardt A, Lucae S, Welt T, Kloiber S, Kern N, Salyakina D, Binder E, Brückl T, Uhr M, Müller-Myhsok B, Holsboer F, Keck M. Polymorphisms in the serotonin receptor gene HTR2A modulate disease severity and susceptibility for anxiety disorders but not depression and are associated with specific personality traits Pharmacopsychiatry. 38. DOI: 10.1055/S-2005-918859  0.251
2018 Reese SE, Xu CJ, den Dekker HT, Lee MK, Sikdar S, Ruiz-Arenas C, Merid SK, Rezwan FI, Page CM, Ullemar V, Melton PE, Oh SS, Yang IV, Burrows K, Söderhäll C, ... ... Binder EB, et al. Epigenome-wide Meta-analysis of DNA Methylation and Childhood Asthma. The Journal of Allergy and Clinical Immunology. PMID 30579849 DOI: 10.1016/J.Jaci.2018.11.043  0.25
2012 Malki K, Lourdusamy A, Binder E, Payá-Cano J, Sluyter F, Craig I, Keers R, McGuffin P, Uher R, Schalkwyk LC. Antidepressant-dependent mRNA changes in mouse associated with hippocampal neurogenesis in a mouse model of depression. Pharmacogenetics and Genomics. 22: 765-76. PMID 23026812 DOI: 10.1097/Fpc.0B013E328356Fa90  0.249
2017 Roeh S, Weber P, Rex-Haffner M, Deussing JM, Binder EB, Jakovcevski M. Sequencing on the SOLiD 5500xl System - in-depth characterization of the GC bias. Nucleus (Austin, Tex.). 0. PMID 28448740 DOI: 10.1080/19491034.2017.1320461  0.249
2016 Joehanes R, Just AC, Marioni RE, Pilling LC, Reynolds LM, Mandaviya PR, Guan W, Xu T, Elks CE, Aslibekyan S, Moreno-Macias H, Smith JA, Brody JA, Dhingra R, Yousefi P, ... ... Binder EB, et al. Epigenetic Signatures of Cigarette Smoking. Circulation. Cardiovascular Genetics. PMID 27651444 DOI: 10.1161/Circgenetics.116.001506  0.248
2015 Wolf C, Mohr H, Diekhof EK, Vieker H, Goya-Maldonado R, Trost S, Krämer B, Keil M, Binder EB, Gruber O. CREB1 Genotype Modulates Adaptive Reward-Based Decisions in Humans. Cerebral Cortex (New York, N.Y. : 1991). PMID 26045569 DOI: 10.1093/Cercor/Bhv104  0.245
2013 Sun YV, Smith AK, Conneely KN, Chang Q, Li W, Lazarus A, Smith JA, Almli LM, Binder EB, Klengel T, Cross D, Turner ST, Ressler KJ, Kardia SL. Epigenomic association analysis identifies smoking-related DNA methylation sites in African Americans. Human Genetics. 132: 1027-37. PMID 23657504 DOI: 10.1007/S00439-013-1311-6  0.245
2021 Mehta D, Grewen K, Pearson B, Wani S, Wallace L, Henders AK, Binder EB, Frokjaer VG, Meltzer-Brody S, Wray NR, Stuebe AM. Genome-wide gene expression changes in postpartum depression point towards an altered immune landscape. Translational Psychiatry. 11: 155. PMID 33664235 DOI: 10.1038/s41398-021-01270-5  0.242
2018 Papac-Milicevic N, Alic L, Czamara D, Gurbisz M, Ozsvar-Kozma M, Haslinger-Hutter S, Hoermann G, Skerka C, Zipfel P, Binder EB, Binder CJ. A genome-wide association study identifies FHR1 and FHR3 as competitors for FH binding to MDA-adducts Molecular Immunology. 102: 195-196. DOI: 10.1016/J.Molimm.2018.06.172  0.242
2019 Czamara D, Eraslan G, Lahti J, Figueiredo AS, Girchenko P, Lahti-Pulkkinen M, Hamalainen E, Kajantie E, Laivuori H, Villa P, Reynolds R, Mueller N, Theis FJ, Raikkonen K, Binder E. Genotype, Prenatal Environment Or Both-What Shapes The Newborn'S Epigenome? European Neuropsychopharmacology. 29: 1037-1037. DOI: 10.1016/J.Euroneuro.2018.07.035  0.241
2013 Jang MH, Kitabatake Y, Kang E, Jun H, Pletnikov MV, Christian KM, Hen R, Lucae S, Binder EB, Song H, Ming GI. Secreted frizzled-related protein 3 (sFRP3) regulates antidepressant responses in mice and humans. Molecular Psychiatry. 18: 957-8. PMID 23207650 DOI: 10.1038/Mp.2012.158  0.24
2017 Felix JF, Joubert BR, Baccarelli AA, Sharp GC, Almqvist C, Annesi-Maesano I, Arshad H, Baïz N, Bakermans-Kranenburg MJ, Bakulski KM, Binder EB, Bouchard L, Breton CV, Brunekreef B, Brunst KJ, et al. Cohort Profile: Pregnancy And Childhood Epigenetics (PACE) Consortium. International Journal of Epidemiology. PMID 29025028 DOI: 10.1093/Ije/Dyx190  0.239
2020 Suarez A, Lahti J, Lahti-Pulkkinen M, Girchenko P, Czamara D, Arloth J, Malmberg AL, Hämäläinen E, Kajantie E, Laivuori H, Villa PM, Reynolds RM, Provençal N, Binder EB, Räikkönen K. A polyepigenetic glucocorticoid exposure score at birth and childhood mental and behavioral disorders. Neurobiology of Stress. 13: 100275. PMID 33344728 DOI: 10.1016/j.ynstr.2020.100275  0.239
2006 Post A, Ackl N, Rücker M, Schreiber Y, Binder EB, Ising M, Sonntag A, Holsboer F, Almeida OF. Toward a reliable distinction between patients with mild cognitive impairment and Alzheimer-type dementia versus major depression. Biological Psychiatry. 59: 858-62. PMID 16325150 DOI: 10.1016/J.Biopsych.2005.09.007  0.239
2006 Milicevic NP, Ryban L, Zaujec J, Binder CJ, Breuss JM, Binder EB, Uhrin P, Binder BR. The interferon inducible gene 12 (ISG12), a novel factor modulating the vascular response to injury Vascular Pharmacology. 45: 186. DOI: 10.1016/J.Vph.2006.08.034  0.239
2023 Yusupov N, van Doeselaar L, Röh S, Wiechmann T, Ködel M, Sauer S, Rex-Haffner M, Schmidt MV, Binder EB. Extensive evaluation of DNA methylation of functional elements in the murine Fkbp5 locus using high-accuracy DNA methylation measurement via targeted bisulfite sequencing. The European Journal of Neuroscience. PMID 37414581 DOI: 10.1111/ejn.16078  0.239
2005 Binder EB, Holsboer F. Pharmacogenomics. Handbook of Experimental Pharmacology. 527-46. PMID 16594271 DOI: 10.1007/3-540-28082-0-19  0.238
2022 Womersley JS, Roeh S, Martin L, Ahmed-Leitao F, Sauer S, Rex-Haffner M, Hemmings SMJ, Binder EB, Seedat S. FKBP5 intron 7 methylation is associated with higher anxiety proneness and smaller right thalamus volume in adolescents. Brain Structure & Function. PMID 36197505 DOI: 10.1007/s00429-022-02577-9  0.238
2013 Blair LJ, Nordhues BA, Hill SE, Scaglione KM, O'Leary JC, Fontaine SN, Breydo L, Zhang B, Li P, Wang L, Cotman C, Paulson HL, Muschol M, Uversky VN, Klengel T, ... Binder EB, et al. Accelerated neurodegeneration through chaperone-mediated oligomerization of tau. The Journal of Clinical Investigation. 123: 4158-69. PMID 23999428 DOI: 10.1172/Jci69003  0.237
2013 Erhardt A, Lucae S, Ising M, Holsboer F, Binder E. Association of PACAP and PACAPR1 gene variants with unipolar depression and panic disorder Pharmacopsychiatry. 46. DOI: 10.1055/S-0033-1353350  0.237
2007 Kohli M, Salyakina D, Binder E, Lucae S, Ising M, Ripke S, Horstmann S, Kloiber S, Pütz B, Lieb R, Uhr M, Müller M, Holsboer F, Müller-Myhsok B. SNPs in the NTRK2 gene are associated with depressive disorder Pharmacopsychiatry. 40. DOI: 10.1055/S-2007-991707  0.236
2013 Uher R, Tansey KE, Rietschel M, Henigsberg N, Maier W, Mors O, Hauser J, Placentino A, Souery D, Farmer A, Aitchison KJ, Craig I, McGuffin P, Lewis CM, Ising M, ... ... Binder EB, et al. Common genetic variation and antidepressant efficacy in major depressive disorder: A meta-analysis of three genome-wide pharmacogenetic studies American Journal of Psychiatry. 170: 207-217. DOI: 10.1176/Appi.Ajp.2012.12020237  0.236
2007 Kohli M, Salyakina D, Binder E, Lucae S, Ising M, Ripke S, Horstmann S, Kloiber S, Pütz B, Fey K, Uhr M, Müller M, Holsboer F, Müller-Myhsok B. SNPs in the NTRK2 gene are associated with age-at-onset of depressive disorder and attempted suicide Pharmacopsychiatry. 40. DOI: 10.1055/S-2007-991706  0.234
2018 Piyasena C, Cartier J, Provencal N, Wiechmann T, Khulan B, Sunderesan R, Menon G, Seckl J, Reynolds RM, Binder EB, Drake AJ. Corrigendum: Dynamic Changes in DNA Methylation Occur during the First Year of Life in Preterm Infants. Frontiers in Endocrinology. 9: 47. PMID 29507579 DOI: 10.3389/fendo.2018.00047  0.234
2006 Baghai TC, Binder EB, Schule C, Salyakina D, Eser D, Lucae S, Zwanzger P, Haberger C, Zill P, Ising M, Deiml T, Uhr M, Illig T, Wichmann HE, Modell S, et al. Polymorphisms in the angiotensin-converting enzyme gene are associated with unipolar depression, ACE activity and hypercortisolism. Molecular Psychiatry. 11: 1003-15. PMID 16924268 DOI: 10.1038/Sj.Mp.4001884  0.231
2023 Arcego DM, Buschdorf JP, O'Toole N, Wang Z, Barth B, Pokhvisneva I, Rayan NA, Patel S, José de Mendonça Filho E, Lee P, Tan J, Koh MX, Sim CM, Parent C, Sobreira de Lima RM, ... ... Binder EB, et al. A glucocorticoid-sensitive hippocampal gene network moderates the impact of early life adversity on mental health outcomes. Biological Psychiatry. PMID 37406925 DOI: 10.1016/j.biopsych.2023.06.028  0.231
2009 Binder EB, Künzel HE, Nickel T, Kern N, Pfennig A, Majer M, Uhr M, Ising M, Holsboer F. HPA-axis regulation at in-patient admission is associated with antidepressant therapy outcome in male but not in female depressed patients. Psychoneuroendocrinology. 34: 99-109. PMID 18829172 DOI: 10.1016/J.Psyneuen.2008.08.018  0.231
2022 Martins J, Yusupov N, Binder EB, Brückl TM, Czamara D. Early adversity as the prototype gene × environment interaction in mental disorders? Pharmacology, Biochemistry, and Behavior. 215: 173371. PMID 35271857 DOI: 10.1016/j.pbb.2022.173371  0.23
2003 Künzel HE, Binder EB, Nickel T, Ising M, Fuchs B, Majer M, Pfennig A, Ernst G, Kern N, Schmid DA, Uhr M, Holsboer F, Modell S. Pharmacological and nonpharmacological factors influencing hypothalamic-pituitary-adrenocortical axis reactivity in acutely depressed psychiatric in-patients, measured by the Dex-CRH test. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 28: 2169-78. PMID 12931142 DOI: 10.1038/Sj.Npp.1300280  0.229
2010 Mehta D, Gonik M, Klengel T, Rex-Haffner M, Mercer-Butze K, Bradley B, Holsboer F, Ressler K, Müller-Myhsok B, Binder E. Cortisol levels and gene expression changes in posttraumatic stress disorder: the role of endophenotypes in determining common biological pathways in psychiatric disorders Experimental and Clinical Endocrinology & Diabetes. 118. DOI: 10.1055/S-0030-1267017  0.227
2017 Girchenko P, Lahti M, Tuovinen S, Savolainen K, Lahti J, Binder EB, Reynolds RM, Entringer S, Buss C, Wadhwa PD, Hämäläinen E, Kajantie E, Pesonen AK, Villa PM, Laivuori H, et al. Cohort Profile: Prediction and prevention of preeclampsia and intrauterine growth restriction (PREDO) study. International Journal of Epidemiology. 46: 1380-1381g. PMID 27639277 DOI: 10.1093/Ije/Dyw154  0.226
2019 Binder EB. Polygenic Risk Scores in Schizophrenia: Ready for the Real World? The American Journal of Psychiatry. 176: 783-784. PMID 31569989 DOI: 10.1176/appi.ajp.2019.19080825  0.226
2016 Klengel T, Howell B, Guzman D, Morin E, Binder E, Ressler K, Sanchez MM. Intergenerational effect of infant maltreatment on epigenetic and functional outcomes in rhesus monkeys Psychoneuroendocrinology. 71: 42. DOI: 10.1016/J.Psyneuen.2016.07.111  0.225
2020 Kaul D, Smith CC, Stevens J, Fröhlich AS, Binder EB, Mechawar N, Schwab SG, Matosin N. Severe childhood and adulthood stress associates with neocortical layer-specific reductions of mature spines in psychiatric disorders. Neurobiology of Stress. 13: 100270. PMID 33344723 DOI: 10.1016/j.ynstr.2020.100270  0.224
2015 Almli LM, Stevens JS, Smith AK, Kilaru V, Meng Q, Flory J, Abu-Amara D, Hammamieh R, Yang R, Mercer KB, Binder EB, Bradley B, Hamilton S, Jett M, Yehuda R, et al. A genome-wide identified risk variant for PTSD is a methylation quantitative trait locus and confers decreased cortical activation to fearful faces. American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics. 168: 327-36. PMID 25988933 DOI: 10.1002/Ajmg.B.32315  0.224
2014 Quast C, Reif A, Brückl T, Pfister H, Weber H, Mattheisen M, Cichon S, Lang T, Hamm A, Fehm L, Ströhle A, Arolt V, Domschke K, Kircher T, Wittchen HU, ... ... Binder EB, et al. Gender-specific association of variants in the AKR1C1 gene with dimensional anxiety in patients with panic disorder: additional evidence for the importance of neurosteroids in anxiety? Depression and Anxiety. 31: 843-50. PMID 24390875 DOI: 10.1002/da.22229  0.224
2023 Kotsakis Ruehlmann A, Sammallahti S, Cortés Hidalgo AP, Bakulski KM, Binder EB, Campbell ML, Caramaschi D, Cecil CAM, Colicino E, Cruceanu C, Czamara D, Dieckmann L, Dou J, Felix JF, Frank J, et al. Epigenome-wide meta-analysis of prenatal maternal stressful life events and newborn DNA methylation. Molecular Psychiatry. PMID 36899042 DOI: 10.1038/s41380-023-02010-5  0.223
2011 Ressler KJ, Mercer KB, Bradley B, Jovanovic T, Mahan A, Kerley K, Norrholm SD, Kilaru V, Smith AK, Myers AJ, Ramirez M, Engel A, Hammack SE, Toufexis D, Braas KM, ... Binder EB, et al. Post-traumatic stress disorder is associated with PACAP and the PAC1 receptor Nature. 477: 120-120. DOI: 10.1038/nature10396  0.221
2021 Rasmusson AJ, Gallwitz M, Soltanabadi B, Ciuculete DM, Mengel-From J, Christensen K, Nygaard M, Soerensen M, Boström AE, Fredriksson R, Freyhult E, Mwinyi J, Czamara D, Binder EB, Schiöth HB, et al. Toll-like receptor 4 methylation grade is linked to depressive symptom severity. Translational Psychiatry. 11: 371. PMID 34226490 DOI: 10.1038/s41398-021-01481-w  0.219
2011 Binder E, Malki K, Paya-Cano JL, Fernandes C, Aitchison KJ, Mathé AA, Sluyter F, Schalkwyk LC. Antidepressants and the resilience to early-life stress in inbred mouse strains. Pharmacogenetics and Genomics. 21: 779-89. PMID 22016050 DOI: 10.1097/Fpc.0B013E32834B3F35  0.218
2015 Menke A, Beintner M, Knop L, Rex-Haffner M, Uhr M, Binder EB. Differentially dexamethasone-regulated FKBP5 RNA and protein expression in peripheral blood F1000research. 6. DOI: 10.7490/F1000Research.1098120.1  0.217
2011 Malki K, Uher R, Paya-Cano J, Binder E, Rietschel M, Zobel A, Mors O, Hauser J, Henigsberg N, Jerman B, Souery D, Placentino A, Ng MY, Cohen-Woods S, Sluyter F, et al. Convergent animal and human evidence suggests a role of PPM1A gene in response to antidepressants. Biological Psychiatry. 69: 360-5. PMID 20970119 DOI: 10.1016/J.Biopsych.2010.08.011  0.214
2013 Ripke S, Wray NR, Lewis CM, Hamilton SP, Weissman MM, Breen G, Byrne EM, Blackwood DH, Boomsma DI, Cichon S, Heath AC, Holsboer F, Lucae S, Madden PA, ... ... Binder EB, et al. A mega-analysis of genome-wide association studies for major depressive disorder. Molecular Psychiatry. 18: 497-511. PMID 22472876 DOI: 10.1038/Mp.2012.21  0.214
2015 Arloth J, Bogdan R, Weber P, Frishman G, Menke A, Wagner KV, Balsevich G, Schmidt MV, Karbalai N, Czamara D, Altmann A, Trümbach D, Wurst W, Mehta D, Uhr M, ... ... Binder EB, et al. Genetic Differences in the Immediate Transcriptome Response to Stress Predict Risk-Related Brain Function and Psychiatric Disorders Neuron. 86: 1189-1202. DOI: 10.1016/j.neuron.2015.05.034  0.214
2013 Nakano W, Mehta D, Ising M, Pfister H, Czamara D, Holsboer F, Lucae S, Erhardt-Lehmann A, Binder E. P.2.b.010 Genetic predictor of antidepressant response for major depressive disorder: a genome-wide association study and pathway analysis European Neuropsychopharmacology. 23: S324-S325. DOI: 10.1016/S0924-977X(13)70509-1  0.214
2022 Kühnel A, Czisch M, Sämann PG, Binder EB, Kroemer NB. Spatiotemporal Dynamics of Stress-Induced Network Reconfigurations Reflect Negative Affectivity. Biological Psychiatry. PMID 35260225 DOI: 10.1016/j.biopsych.2022.01.008  0.213
2021 Athreya AP, Brückl T, Binder EB, John Rush A, Biernacka J, Frye MA, Neavin D, Skime M, Monrad D, Iyer RK, Mayes T, Trivedi M, Carter RE, Wang L, Weinshilboum RM, et al. Prediction of short-term antidepressant response using probabilistic graphical models with replication across multiple drugs and treatment settings. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 33452433 DOI: 10.1038/s41386-020-00943-x  0.211
2018 Penner-Goeke S, Provencal N, Jakovcevski M, Roeh S, Binder E. F121. Investigating Glucocorticoid Receptor Binding in Lymphoblastoid Cell Lines Biological Psychiatry. 83. DOI: 10.1016/J.Biopsych.2018.02.734  0.21
2013 Blair L, Nordhues B, Hill S, Scaglione KM, O'Leary J, Breydo L, Bo Z, Li P, Wang L, Cotman C, Paulson H, Muschol M, Uversky V, Klengel T, Binder E, et al. The Hsp90 co-chaperone FKBP51 produces neurotoxic tau oligomers: Implication for aging and Alzheimer's disease Alzheimers & Dementia. 9: 173. DOI: 10.1016/J.Jalz.2013.05.279  0.209
2021 Kappelmann N, Czamara D, Rost N, Moser S, Schmoll V, Trastulla L, Stochl J, Lucae S, Binder EB, Khandaker GM, Arloth J. Polygenic risk for immuno-metabolic markers and specific depressive symptoms: A multi-sample network analysis study. Brain, Behavior, and Immunity. PMID 33794315 DOI: 10.1016/j.bbi.2021.03.024  0.208
2009 Thoeringer CK, Ripke S, Unschuld PG, Lucae S, Ising M, Bettecken T, Uhr M, Keck ME, Mueller-Myhsok B, Holsboer F, Binder EB, Erhardt A. The GABA transporter 1 (SLC6A1): a novel candidate gene for anxiety disorders. Journal of Neural Transmission (Vienna, Austria : 1996). 116: 649-57. PMID 18607529 DOI: 10.1007/S00702-008-0075-Y  0.207
2017 Mehta D, Bruenig D, Carrillo-Roa T, Lawford B, Harvey W, Morris CP, Smith AK, Binder EB, Young RM, Voisey J. Genomewide DNA methylation analysis in combat veterans reveals a novel locus for PTSD. Acta Psychiatrica Scandinavica. PMID 28795405 DOI: 10.1111/acps.12778  0.206
2023 Matosin N, Arloth J, Czamara D, Edmond KZ, Maitra M, Fröhlich AS, Martinelli S, Kaul D, Bartlett R, Curry AR, Gassen NC, Hafner K, Müller NS, Worf K, Rehawi G, ... ... Binder EB, et al. Associations of psychiatric disease and ageing with FKBP5 expression converge on superficial layer neurons of the neocortex. Acta Neuropathologica. PMID 36729133 DOI: 10.1007/s00401-023-02541-9  0.206
2012 Binder E. CS03-03 - Allele-specific epigenetic changes: molecular mediators of gene x environment interactions in mood and anxiety disorders? European Psychiatry. 27: 1. DOI: 10.1016/S0924-9338(12)74066-X  0.204
2019 Mullins N, Bigdeli TB, Børglum AD, Coleman JRI, Demontis D, Mehta D, Power RA, Ripke S, Stahl EA, Starnawska A, Anjorin A, Corvin A, Sanders AR, Forstner AJ, ... ... Binder EB, et al. GWAS of Suicide Attempt in Psychiatric Disorders and Association With Major Depression Polygenic Risk Scores. The American Journal of Psychiatry. appiajp201918080957. PMID 31164008 DOI: 10.1176/Appi.Ajp.2019.18080957  0.204
2008 Horstmann S, Lucae S, Menke A, Ising M, Müller-Myhsok B, Holsboer F, Binder E. P.1.a.021 Association of GRIK4 and HTR2A genes with antidepressant treatment in the MARS cohort of depressed inpatients European Neuropsychopharmacology. 18: S214-S215. DOI: 10.1016/S0924-977X(08)70255-4  0.203
2023 Yusupov N, Dieckmann L, Erhart M, Sauer S, Rex-Haffner M, Kopf-Beck J, Brückl TM, Czamara D, Binder EB. Transdiagnostic evaluation of epigenetic age acceleration and burden of psychiatric disorders. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 37069357 DOI: 10.1038/s41386-023-01579-3  0.202
2022 Gerstner N, Krontira AC, Cruceanu C, Roeh S, Pütz B, Sauer S, Rex-Haffner M, Schmidt MV, Binder EB, Knauer-Arloth J. DiffBrainNet: Differential analyses add new insights into the response to glucocorticoids at the level of genes, networks and brain regions. Neurobiology of Stress. 21: 100496. PMID 36532379 DOI: 10.1016/j.ynstr.2022.100496  0.2
2004 Keck ME, Müller MB, Binder EB, Sonntag A, Holsboer F. Ziprasidone-related tardive dyskinesia. The American Journal of Psychiatry. 161: 175-6. PMID 14702272 DOI: 10.1176/Appi.Ajp.161.1.175-A  0.199
2020 Schneider M, Elbau IG, Nantawisarakul T, Pöhlchen D, Brückl T, BeCOME Working Group, Czisch M, Saemann PG, Lee MD, Binder EB, Spoormaker VI. Pupil Dilation during Reward Anticipation Is Correlated to Depressive Symptom Load in Patients with Major Depressive Disorder. Brain Sciences. 10. PMID 33255604 DOI: 10.3390/brainsci10120906  0.199
2011 Schosser A, Gaysina D, Cohen-Woods S, Domenici E, Perry J, Tozzi F, Korszun A, Gunasinghe C, Gray J, Jones L, Binder EB, Holsboer F, Craddock N, Owen MJ, Craig IW, et al. A follow-up case-control association study of tractable (druggable) genes in recurrent major depression. American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics. 156: 640-50. PMID 21630437 DOI: 10.1002/Ajmg.B.31204  0.198
2023 Miller AH, Binder EB. Guilt by Association: Inflammation and Shared Genetic Risk Between Stress-Related and Immune Disorders. The American Journal of Psychiatry. 180: 259-261. PMID 37002689 DOI: 10.1176/appi.ajp.20230078  0.196
2021 van Dongen J, Hagenbeek FA, Suderman M, Roetman PJ, Sugden K, Chiocchetti AG, Ismail K, Mulder RH, Hafferty JD, Adams MJ, Walker RM, Morris SW, Lahti J, Küpers LK, Escaramis G, ... ... Binder E, et al. DNA methylation signatures of aggression and closely related constructs: A meta-analysis of epigenome-wide studies across the lifespan. Molecular Psychiatry. PMID 33420481 DOI: 10.1038/s41380-020-00987-x  0.195
2007 Göder R, Fritzer G, Hinze-Selch D, Huchzermeier C, Koch JM, Seeck-Hirschner M, Aldenhoff JB, Okugawa G, Nobuhara K, Takase K, Saito Y, Yoshimura M, Kinoshita T, Strik W, Uhr M, ... ... Binder EB, et al. 27th Annual Meeting of the Swiss Society of Biological Psychiatry Neuropsychobiology. 55: 52-72. DOI: 10.1159/000103455  0.195
2020 Kalin NH, Binder E, Brady KT, Lewis DA, Pine DS, Rodriguez C, Trivedi M, Rosenberg S. 2019 Articles of Import and Impact. The American Journal of Psychiatry. 177: 17-19. PMID 31892299 DOI: 10.1176/Appi.Ajp.2019.19111124  0.194
2022 Airikka A, Lahti-Pulkkinen M, Tuovinen S, Heinonen K, Lahti J, Girchenko P, Lähdepuro A, Pyhälä R, Czamara D, Villa P, Laivuori H, Kajantie E, Binder EB, Räikkönen K. Maternal exposure to childhood maltreatment and mental and behavioral disorders in children. European Child & Adolescent Psychiatry. PMID 36181574 DOI: 10.1007/s00787-022-02090-8  0.194
2008 Ressler KJ, Bradley RG, Cubells JF, Binder EB. Child abuse and adult major depression: No evidence of protective gene: Reply Archives of General Psychiatry. 65: 1337-1339. DOI: 10.1001/archpsyc.65.11.1337  0.194
2023 Zannas AS, Linnstaedt SD, An X, Stevens JS, Harnett NG, Roeckner AR, Oliver KI, Rubinow DR, Binder EB, Koenen KC, Ressler KJ, McLean SA. Epigenetic aging and PTSD outcomes in the immediate aftermath of trauma. Psychological Medicine. 1-10. PMID 36951141 DOI: 10.1017/S0033291723000636  0.193
2023 Kühnel A, Hagenberg J, Knauer-Arloth J, Ködel M, Czisch M, Sämann PG, Binder EB, Kroemer NB. Stress-induced brain responses are associated with BMI in women. Communications Biology. 6: 1031. PMID 37821711 DOI: 10.1038/s42003-023-05396-8  0.192
2006 Binder E, Lucae S, Salyakina D, Lichtner P, Meitinger T, Bondy B, Wochnik G, Rein T, Holsboer F, Müller-Myhsok B. SNPs in FKBP5 determine a novel subtype of depression characterized by rapid response to antidepressant treatment European Neuropsychopharmacology. 16: S75. DOI: 10.1016/S0924-977X(06)80089-1  0.19
2017 Binder E. Das Chaperon-Protein FKBP5: Target zur Verbesserung der Stressresistenz Drug Research. 67. PMID 29069685 DOI: 10.1055/S-0043-116536  0.189
2020 Kappelmann N, Arloth J, Georgakis MK, Czamara D, Rost N, Ligthart S, Khandaker GM, Binder EB. Dissecting the Association Between Inflammation, Metabolic Dysregulation, and Specific Depressive Symptoms: A Genetic Correlation and 2-Sample Mendelian Randomization Study. Jama Psychiatry. PMID 33079133 DOI: 10.1001/jamapsychiatry.2020.3436  0.189
2022 Czamara D, Cruceanu C, Lahti-Pulkkinen M, Dieckmann L, Ködel M, Sauer S, Rex-Haffner M, Sammallahti S, Kajantie E, Laivuori H, Lahti J, Räikkönen K, Binder EB. Genome-Wide Copy Number Variant and High-Throughput Transcriptomics Analyses of Placental Tissues Underscore Persisting Child Susceptibility in At-Risk Pregnancies Cleared in Standard Genetic Testing. International Journal of Molecular Sciences. 23. PMID 36232765 DOI: 10.3390/ijms231911448  0.187
2011 Erhardt A, Czibere L, Roeske D, Lucae S, Unschuld PG, Ripke S, Specht M, Kohli MA, Kloiber S, Ising M, Heck A, Pfister H, Zimmermann P, Lieb R, Pütz B, ... ... Binder EB, et al. TMEM132D, a new candidate for anxiety phenotypes: evidence from human and mouse studies. Molecular Psychiatry. 16: 647-63. PMID 20368705 DOI: 10.1038/Mp.2010.41  0.186
2017 Jukić MM, Opel N, Ström J, Carrillo-Roa T, Miksys S, Novalen M, Renblom A, Sim SC, Peñas-Lledó EM, Courtet P, Llerena A, Baune BT, de Quervain DJ, Papassotiropoulos A, Tyndale RF, ... Binder EB, et al. Elevated CYP2C19 expression is associated with depressive symptoms and hippocampal homeostasis impairment. Molecular Psychiatry. PMID 28416806 DOI: 10.1038/mp.2017.93  0.185
2007 Barber DS, Hancock SK, McNally AM, Hinckley J, Binder E, Zimmerman K, Ehrich MF, Jortner BS. Neurological effects of acute uranium exposure with and without stress. Neurotoxicology. 28: 1110-9. PMID 17669499 DOI: 10.1016/J.Neuro.2007.05.014  0.183
2020 Kalin NH, Binder E, Brady KT, Lewis DA, Pine DS, Rodriguez C, Trivedi MH. 's Commitment to Combat Racism, Social Injustice, and Health Care Inequities. The American Journal of Psychiatry. 177: 791. PMID 32867519 DOI: 10.1176/Appi.Ajp.2020.20071051  0.182
2020 Neumann A, Walton E, Alemany S, Cecil C, González JR, Jima DD, Lahti J, Tuominen ST, Barker ED, Binder E, Caramaschi D, Carracedo Á, Czamara D, Evandt J, Felix JF, et al. Association between DNA methylation and ADHD symptoms from birth to school age: a prospective meta-analysis. Translational Psychiatry. 10: 398. PMID 33184255 DOI: 10.1038/s41398-020-01058-z  0.182
2011 Menke A, Klengel T, Eichelkraut A, Preis L, Rex-Haffner M, Uhr M, Holsboer F, Binder E. P.1.a.021 Glucocorticoid induced FKBP5-gene expression in depressed patients and healthy controls European Neuropsychopharmacology. 21: S248-S249. DOI: 10.1016/S0924-977X(11)70384-4  0.181
2023 Felt JM, Yusupov N, Harrington KD, Fietz J, Zhang ZZ, Sliwinski MJ, Ram N, O'Donnell KJ, Meaney MJ, Putnam FW, Noll JG, Binder EB, Shenk CE. Epigenetic age acceleration as a biomarker for impaired cognitive abilities in adulthood following early life adversity and psychiatric disorders. Neurobiology of Stress. 27: 100577. PMID 37885906 DOI: 10.1016/j.ynstr.2023.100577  0.18
2007 Baghai TC, Binder E, Schüle C, Lucae S, Eser D, Müller-Myhsok B, Möller H, Holsboer F, Rupprecht R, Bondy B. Assoziation zwischen Herzerkrankungen und Depressionen Biologie in Unserer Zeit. 37: 284-286. DOI: 10.1002/Biuz.200790076  0.18
2012 Malki K, Campbell J, Davies M, Keers R, Uher R, Ward M, Paya-Cano J, Aitchinson KJ, Binder E, Sluyter F, Kuhn K, Selzer S, Craig I, McGuffin P, Schalkwyk LC. Pharmacoproteomic investigation into antidepressant response in two mouse inbred strains. Proteomics. 12: 2355-65. PMID 22696452 DOI: 10.1002/Pmic.201100306  0.179
2023 von Mücke-Heim IA, Pape JC, Grandi NC, Erhardt A, Deussing JM, Binder EB. Multiomics and blood-based biomarkers of electroconvulsive therapy in severe and treatment-resistant depression: study protocol of the DetECT study. European Archives of Psychiatry and Clinical Neuroscience. PMID 37644215 DOI: 10.1007/s00406-023-01647-1  0.178
2011 Quast C, Altmann A, Weber P, Rex-Haffner M, Erhardt A, Müller-Myhsok B, Binder E. P.1.006 Screening for rare variants in TMEM132D: a candidate gene from genome-wide association studies in anxiety disorders European Neuropsychopharmacology. 21: S6-S7. DOI: 10.1016/S0924-977X(11)70007-4  0.178
2009 Ising M, Lucae S, Binder E, Bettecken T, Uhr M, Ripke S, Kohli M, Hennings J, Horstmann S, Kloiber S, Menke A, Bondy B, Rupprecht R, Domschke K, Baune B, et al. A genome-wide association study points to multiple loci predicting antidepressant treatment outcome in depression Pharmacopsychiatry. 42. DOI: 10.1055/S-0029-1240141  0.177
2020 Liu D, Zhuang Y, Zhang L, Gao H, Neavin D, Carrillo-Roa T, Wang Y, Yu J, Qin S, Kim DC, Liu E, Nguyen TTL, Biernacka JM, Kaddurah-Daouk R, Dunlop BW, ... ... Binder EB, et al. ERICH3: vesicular association and antidepressant treatment response. Molecular Psychiatry. PMID 33230203 DOI: 10.1038/s41380-020-00940-y  0.177
2022 Budziñski ML, Sokn C, Gobbini R, Ugo B, Antunica-Noguerol M, Senin S, Bajaj T, Gassen NC, Rein T, Schmidt MV, Binder EB, Arzt E, Liberman AC. Tricyclic antidepressants target FKBP51 SUMOylation to restore glucocorticoid receptor activity. Molecular Psychiatry. PMID 35256747 DOI: 10.1038/s41380-022-01491-0  0.177
2004 Kern N, Binder E, Künzel H, Pfennig A, Fuchs B, Ising M, Erhardt A, Lucae S, Müller-Myhsok B, Modell S, Keck M, Holsboer F. Is there a genetic continuum between anxiety and depression? Pharmacopsychiatry. 36. DOI: 10.1055/S-2003-825399  0.176
2012 Menke A, Arloth J, Pütz B, Weber P, Klengel T, Mehta D, Gonik M, Rex-Haffner M, Rubel J, Uhr M, Lucae S, Deussing JM, Müller-Myhsok B, Holsboer F, Binder EB. Dexamethasone stimulated gene expression in peripheral blood is a sensitive marker for glucocorticoid receptor resistance in depressed patients (Neuropsychopharmacology (2012) 37, (1455-1464) DOI: 10.1038/npp.2011.331) Neuropsychopharmacology. 37: 1972. DOI: 10.1038/npp.2012.21  0.175
2021 Crombie KM, Privratsky AA, Schomaker CM, Heilicher M, Ross MC, Sartin-Tarm A, Sellnow K, Binder EB, Andrew James G, Cisler JM. The influence of FAAH genetic variation on physiological, cognitive, and neural signatures of fear acquisition and extinction learning in women with PTSD. Neuroimage. Clinical. 33: 102922. PMID 34952353 DOI: 10.1016/j.nicl.2021.102922  0.174
2022 Solomon O, Huen K, Yousefi P, Küpers LK, González JR, Suderman M, Reese SE, Page CM, Gruzieva O, Rzehak P, Gao L, Bakulski KM, Novoloaca A, Allard C, Pappa I, ... ... Binder EB, et al. Meta-analysis of epigenome-wide association studies in newborns and children show widespread sex differences in blood DNA methylation. Mutation Research. Reviews in Mutation Research. 789: 108415. PMID 35690418 DOI: 10.1016/j.mrrev.2022.108415  0.174
2004 Pfennig A, Kuenzel H, Kern N, Fuchs B, Brunner J, Ising M, Modell S, Müller-Myhsok B, Binder E, Holsboer F. HPA axis dysregulation and suicidal behavior in depression – Differentiation of a genetically distinct subgroup? Pharmacopsychiatry. 36. DOI: 10.1055/S-2003-825457  0.173
2017 Brückl TM, Binder EB. Folgen früher Traumatisierung aus neurobiologischer Sicht Forensische Psychiatrie, Psychologie, Kriminologie. 11: 118-132. DOI: 10.1007/s11757-017-0412-9  0.173
2009 Bull SJ, Huezo-Diaz P, Binder EB, Cubells JF, Ranjith G, Maddock C, Miyazaki C, Alexander N, Hotopf M, Cleare AJ, Norris S, Cassidy E, Aitchison KJ, Miller AH, Pariante CM. Functional polymorphisms in the interleukin-6 and serotonin transporter genes, and depression and fatigue induced by interferon-alpha and ribavirin treatment. Molecular Psychiatry. 14: 1095-104. PMID 18458677 DOI: 10.1038/Mp.2008.48  0.171
2015 Ferentinos P, Koukounari A, Power R, Rivera M, Uher R, Craddock N, Owen MJ, Korszun A, Jones L, Jones I, Gill M, Rice JP, Ising M, Maier W, Mors O, ... ... Binder EB, et al. Familiality and SNP heritability of age at onset and episodicity in major depressive disorder. Psychological Medicine. 1-11. PMID 25698070 DOI: 10.1017/S0033291715000215  0.171
2022 Rost N, Binder EB, Brückl TM. Predicting treatment outcome in depression: an introduction into current concepts and challenges. European Archives of Psychiatry and Clinical Neuroscience. PMID 35587279 DOI: 10.1007/s00406-022-01418-4  0.171
2009 Wegerer M, Adena S, Binder E, Huber J, Sailer U, Bettecken T, Müller-Myhsok B, Modell S, Holsboer F, Ising M. Polymorphisms within the 4-aminobutyrate aminotransferase gene are associated with long-latency somatosensory potentials in families vulnerable for affective disorders Pharmacopsychiatry. 42. DOI: 10.1055/S-0029-1240248  0.17
2008 Ising M, Adena S, Binder E, Pfennig A, Schalling M, Mueller-Myhsok B, Modell S, Holsboer F. Genetic determinants of neurobiological vulnerability markers in depression European Psychiatry. 23: S9. DOI: 10.1016/J.Eurpsy.2008.01.035  0.169
2021 Høgh S, Hegaard HK, Renault KM, Cvetanovska E, Kjærbye-Thygesen A, Juul A, Borgsted C, Bjertrup AJ, Miskowiak KW, Væver MS, Stenbæk DS, Dam VH, Binder E, Ozenne B, Mehta D, et al. Short-term oestrogen as a strategy to prevent postpartum depression in high-risk women: protocol for the double-blind, randomised, placebo-controlled MAMA clinical trial. Bmj Open. 11: e052922. PMID 35763351 DOI: 10.1136/bmjopen-2021-052922  0.167
2005 Ising M, Binder E, Dose T, Horstmann S, Kern N, Kloiber S, Künzel H, Lucae S, Pfennig A, Unschuld P, Modell S, Holsboer F. Change in HPA system function predicts treatment response in depression Pharmacopsychiatry. 38. DOI: 10.1055/S-2005-918726  0.166
2022 Falkai P, Koutsouleris N, Bertsch K, Bialas M, Binder E, Bühner M, Buyx A, Cai N, Cappello S, Ehring T, Gensichen J, Hamann J, Hasan A, Henningsen P, Leucht S, et al. Concept of the Munich/Augsburg Consortium Precision in Mental Health for the German Center of Mental Health. Frontiers in Psychiatry. 13: 815718. PMID 35308871 DOI: 10.3389/fpsyt.2022.815718  0.165
2022 Kvist T, Sammallahti S, Lahti-Pulkkinen M, Cruceanu C, Czamara D, Dieckmann L, Tontsch A, Röh S, Rex-Haffner M, Wolford E, Reynolds R, Eriksson J, Suomalainen-König S, Laivuori H, Kajantie E, ... ... Binder E, et al. Cohort profile: InTraUterine sampling in early pregnancy (ITU), a prospective pregnancy cohort study in Finland: study design and baseline characteristics. Bmj Open. 12: e049231. PMID 35105615 DOI: 10.1136/bmjopen-2021-049231  0.164
2023 Rost N, Dwyer DB, Gaffron S, Rechberger S, Maier D, Binder EB, Brückl TM. Multimodal predictions of treatment outcome in major depression: A comparison of data-driven predictors with importance ratings by clinicians. Journal of Affective Disorders. PMID 36750160 DOI: 10.1016/j.jad.2023.02.007  0.163
2012 Binder EB. The genetic basis of mood and anxiety disorders - changing paradigms. Biology of Mood & Anxiety Disorders. 2: 17. PMID 23025470 DOI: 10.1186/2045-5380-2-17  0.163
2020 Ronkainen J, Heiskala A, Vehmeijer FOL, Lowry E, Caramaschi D, Estrada Gutiérrez G, Heiss JA, Hummel N, Keikkala E, Kvist T, Kupsco A, Melton PE, Pesce G, Soomro MH, Vives-Usano M, ... ... Binder E, et al. Maternal haemoglobin levels in pregnancy and child DNA methylation: a study in the Pregnancy And Childhood Epigenetics Consortium. Epigenetics. PMID 33331245 DOI: 10.1080/15592294.2020.1864171  0.163
2024 Raabe FJ, Hausruckinger A, Gagliardi M, Ahmad R, Almeida V, Galinski S, Hoffmann A, Weigert L, Rummel CK, Murek V, Trastulla L, Jimenez-Barron L, Atella A, Maidl S, Menegaz D, ... ... Binder EB, et al. Polygenic risk for schizophrenia converges on alternative polyadenylation as molecular mechanism underlying synaptic impairment. Biorxiv : the Preprint Server For Biology. PMID 38260577 DOI: 10.1101/2024.01.09.574815  0.162
2011 Klengel T, Binder EB. Using gene-environment interactions to target personalized treatment in mood disorder Personalized Medicine. 8: 23-34. DOI: 10.2217/pme.10.73  0.161
2021 Min JL, Hemani G, Hannon E, Dekkers KF, Castillo-Fernandez J, Luijk R, Carnero-Montoro E, Lawson DJ, Burrows K, Suderman M, Bretherick AD, Richardson TG, Klughammer J, Iotchkova V, Sharp G, ... ... Binder EB, et al. Genomic and phenotypic insights from an atlas of genetic effects on DNA methylation. Nature Genetics. 53: 1311-1321. PMID 34493871 DOI: 10.1038/s41588-021-00923-x  0.16
2008 Hodgkinson CA, Yuan Q, Xu K, Shen PH, Heinz E, Lobos EA, Binder EB, Cubells J, Ehlers CL, Gelernter J, Mann J, Riley B, Roy A, Tabakoff B, Todd RD, et al. Addictions biology: haplotype-based analysis for 130 candidate genes on a single array. Alcohol and Alcoholism (Oxford, Oxfordshire). 43: 505-15. PMID 18477577 DOI: 10.1093/Alcalc/Agn032  0.157
2022 Scherf-Clavel M, Weber H, Wurst C, Stonawski S, Hommers L, Unterecker S, Wolf C, Domschke K, Rost N, Brückl T, Lucae S, Uhr M, Binder EB, Menke A, Deckert J. Effects of Pharmacokinetic Gene Variation on Therapeutic Drug Levels and Antidepressant Treatment Response. Pharmacopsychiatry. PMID 35839823 DOI: 10.1055/a-1872-0613  0.156
2015 Howe AS, Buttenschøn HN, Bani-Fatemi A, Maron E, Otowa T, Erhardt A, Binder EB, Gregersen NO, Mors O, Woldbye DP, Domschke K, Reif A, Shlik J, Kõks S, Kawamura Y, et al. Candidate genes in panic disorder: meta-analyses of 23 common variants in major anxiogenic pathways. Molecular Psychiatry. PMID 26390831 DOI: 10.1038/Mp.2015.138  0.156
2004 Majer M, Ising M, Künzel H, Binder EB, Holsboer F, Modell S, Zihl J. Impaired divided attention predicts delayed response and risk to relapse in subjects with depressive disorders. Psychological Medicine. 34: 1453-63. PMID 15724876 DOI: 10.1017/S0033291704002697  0.156
2022 Rost N, Brückl TM, Koutsouleris N, Binder EB, Müller-Myhsok B. Creating sparser prediction models of treatment outcome in depression: a proof-of-concept study using simultaneous feature selection and hyperparameter tuning. Bmc Medical Informatics and Decision Making. 22: 181. PMID 35836174 DOI: 10.1186/s12911-022-01926-2  0.155
2020 McLean SA, Ressler K, Koenen KC, Neylan T, Germine L, Jovanovic T, Clifford GD, Zeng D, An X, Linnstaedt S, Beaudoin F, House S, Bollen KA, Musey P, Hendry P, ... ... Binder E, et al. Correction: The AURORA Study: a longitudinal, multimodal library of brain biology and function after traumatic stress exposure. Molecular Psychiatry. PMID 32989243 DOI: 10.1038/s41380-020-00897-y  0.154
2014 Zannas A, Klengel T, Binder E. P.1.027 The role of FKBP5 in mechanisms linking stress and aging European Neuropsychopharmacology. 24: S25-S26. DOI: 10.1016/S0924-977X(14)70029-X  0.153
2011 Labermaier C, Liebl C, Scharf S, Sillaber I, Binder E, Müller M. Epigenetic modifications determining variability in antidepressant response: beyond genetic association studies Pharmacopsychiatry. 44. DOI: 10.1055/S-0031-1292512  0.152
2005 Salyakina D, Binder E, Ising M, Uhr M, Lucae S, Müller-Myhsok B. Within- and Inter- gene interactions in FKBP5 and GR genes and its association with early response Pharmacopsychiatry. 38. DOI: 10.1055/S-2005-918825  0.152
2012 Erhardt A, Akula N, Schumacher J, Czamara D, Karbalai N, Müller-Myhsok B, Mors O, Borglum A, Kristensen AS, Woldbye DP, Koefoed P, Eriksson E, Maron E, Metspalu A, Nurnberger J, ... ... Binder EB, et al. Replication and meta-analysis of TMEM132D gene variants in panic disorder. Translational Psychiatry. 2: e156. PMID 22948381 DOI: 10.1038/Tp.2012.85  0.151
2015 Gassen NC, Hartmann J, Zannas AS, Kretzschmar A, Zschocke J, Maccarrone G, Hafner K, Zellner A, Kollmannsberger LK, Wagner KV, Mehta D, Kloiber S, Turck CW, Lucae S, Chrousos GP, ... ... Binder EB, et al. FKBP51 inhibits GSK3β and augments the effects of distinct psychotropic medications. Molecular Psychiatry. PMID 25849320 DOI: 10.1038/Mp.2015.38  0.151
2015 Rampp C, Eichelkraut A, Best J, Uhr M, Binder E, Menke A. Gender related differential response to dexamethasone in endocrine and immune measures in depressed patients and healthy controls Pharmacopsychiatry. 48. DOI: 10.1055/S-0035-1557986  0.151
2021 Czamara D, Dieckmann L, Röh S, Kraemer S, Rancourt RC, Sammallahti S, Kajantie E, Laivuori H, Eriksson JG, Räikkönen K, Henrich W, Plagemann A, Binder EB, Braun T, Entringer S. Betamethasone administration during pregnancy is associated with placental epigenetic changes with implications for inflammation. Clinical Epigenetics. 13: 165. PMID 34446099 DOI: 10.1186/s13148-021-01153-y  0.151
2009 Kloiber S, Kohli M, Brückl T, Ripke S, Ising M, Uhr M, Menke A, Unschuld P, Horstmann S, Salyakina D, Müller-Myhsok B, Binder E, Holsboer F, Lucae S. Polymorphisms in tryptophan hydroxylase 2 leading to decreased serotonergic activity contribute to elevated risk for metabolic syndrome in depression Pharmacopsychiatry. 42. DOI: 10.1055/S-0029-1240151  0.15
2009 Hennings J, Owashi T, Binder E, Horstmann S, Menke A, Kloiber S, Uhr M, Ising M, Holsboer F, Lucae S. P.3.08 Clinical characteristics and treatment outcome in a representative sample of depressed inpatients European Neuropsychopharmacology. 19: S68-S69. DOI: 10.1016/S0924-977X(09)70078-1  0.147
2022 Tobi EW, Juvinao-Quintero DL, Ronkainen J, Ott R, Alfano R, Canouil M, Geurtsen ML, Khamis A, Küpers LK, Lim IY, Perron P, Pesce G, Tuhkanen J, Starling AP, Andrew T, ... Binder E, et al. Maternal Glycemic Dysregulation During Pregnancy and Neonatal Blood DNA Methylation: Meta-analyses of Epigenome-Wide Association Studies. Diabetes Care. PMID 35104326 DOI: 10.2337/dc21-1701  0.146
2021 Mullins N, Kang J, Campos AI, Coleman JRI, Edwards AC, Galfalvy H, Levey DF, Lori A, Shabalin A, Starnawska A, Su MH, Watson HJ, Adams M, Awasthi S, Gandal M, ... ... Binder EB, et al. Dissecting the Shared Genetic Architecture of Suicide Attempt, Psychiatric Disorders, and Known Risk Factors. Biological Psychiatry. PMID 34861974 DOI: 10.1016/j.biopsych.2021.05.029  0.145
2013 Bellocchio L, Soria-Gómez E, Quarta C, Metna-Laurent M, Cardinal P, Binder E, Cannich A, Delamarre A, Häring M, Martín-Fontecha M, Vega D, Leste-Lasserre T, Bartsch D, Monory K, Lutz B, et al. Activation of the sympathetic nervous system mediates hypophagic and anxiety-like effects of CB₁ receptor blockade. Proceedings of the National Academy of Sciences of the United States of America. 110: 4786-91. PMID 23487769 DOI: 10.1073/Pnas.1218573110  0.144
2015 Elbau I, Brücklmeier B, Spoormaker V, Binder E, Czisch M, Sämann P. Acute psychosocial stress investigated by an imaging stress test: concept and preliminary results Pharmacopsychiatry. 48. DOI: 10.1055/s-0035-1557947  0.142
2023 Docherty AR, Mullins N, Ashley-Koch AE, Qin X, Coleman JRI, Shabalin A, Kang J, Murnyak B, Wendt F, Adams M, Campos AI, DiBlasi E, Fullerton JM, Kranzler HR, Bakian AV, ... ... Binder EB, et al. GWAS Meta-Analysis of Suicide Attempt: Identification of 12 Genome-Wide Significant Loci and Implication of Genetic Risks for Specific Health Factors. The American Journal of Psychiatry. 180: 723-738. PMID 37777856 DOI: 10.1176/appi.ajp.21121266  0.141
2003 Müller MB, Keck ME, Binder EB, Kresse AE, Hagemeyer TP, Landgraf R, Holsboer F, Uhr M. ABCBI (MDRI)-Type P-Glycoproteins at the Blood-Brain Barrier Modulate the Activity of the Hypothalamic-Pituitary-Adrenocortical System: Implications for Affective Disorder Neuropsychopharmacology. 28: 1991-1999.  0.137
2010 Horstmann S, Menke A, Straub V, Hennings J, Lucae S, Wollweber S, Binder E. P.1.016 Association of the adrenergic receptor alpha1β with antidepressant treatment in the MARS study European Neuropsychopharmacology. 20: S15-S16. DOI: 10.1016/S0924-977X(10)70019-5  0.135
2013 Menke A, Kloiber S, Best J, Rex-Haffner M, Uhr M, Holsboer F, Binder E. GR-mediated FKBP5 RNA induction differentially influenced by weight in major depression and healthy controls Pharmacopsychiatry. 46. DOI: 10.1055/S-0033-1353276  0.133
2009 Menke A, Roeske D, Domschke K, Holsboer F, Binder E. Genome-wide association study of antidepressant induced treatment emergent suicidal ideation (TESI) Pharmacopsychiatry. 42. DOI: 10.1055/S-0029-1240171  0.133
2016 Liu C, Marioni RE, Hedman ÅK, Pfeiffer L, Tsai PC, Reynolds LM, Just AC, Duan Q, Boer CG, Tanaka T, Elks CE, Aslibekyan S, Brody JA, Kühnel B, Herder C, ... ... Binder EB, et al. A DNA methylation biomarker of alcohol consumption. Molecular Psychiatry. PMID 27843151 DOI: 10.1038/Mp.2016.192  0.131
2021 Cruceanu C, Dony L, Krontira AC, Fischer DS, Roeh S, Di Giaimo R, Kyrousi C, Kaspar L, Arloth J, Czamara D, Gerstner N, Martinelli S, Wehner S, Breen MS, Koedel M, ... ... Binder EB, et al. Cell-Type-Specific Impact of Glucocorticoid Receptor Activation on the Developing Brain: A Cerebral Organoid Study. The American Journal of Psychiatry. appiajp202121010095. PMID 34698522 DOI: 10.1176/appi.ajp.2021.21010095  0.126
2020 Vehmeijer FOL, Küpers LK, Sharp GC, Salas LA, Lent S, Jima DD, Tindula G, Reese S, Qi C, Gruzieva O, Page C, Rezwan FI, Melton PE, Nohr E, Escaramís G, ... ... Binder E, et al. DNA methylation and body mass index from birth to adolescence: meta-analyses of epigenome-wide association studies. Genome Medicine. 12: 105. PMID 33239103 DOI: 10.1186/s13073-020-00810-w  0.126
2005 Thoeringer C, Binder E, Lucae S, Erhardt A, Unschuld P, Harbich D, Roedel A, Uhr M, Ohl F, Lieb R, Müller-Myhsok B, Müller M, Holsboer F. GABA transporter1 (GAT1) inhibition mediates distinct emotional and cognitive processes and represents a possible treatment strategy compensating genetic polymorphisms in panic disorder Pharmacopsychiatry. 38. DOI: 10.1055/S-2005-918854  0.124
2021 Dieckmann L, Lahti-Pulkkinen M, Kvist T, Lahti J, DeWitt PE, Cruceanu C, Laivuori H, Sammallahti S, Villa PM, Suomalainen-König S, Eriksson JG, Kajantie E, Raikkönen K, Binder EB, Czamara D. Characteristics of epigenetic aging across gestational and perinatal tissues. Clinical Epigenetics. 13: 97. PMID 33926514 DOI: 10.1186/s13148-021-01080-y  0.122
2019 Cruceanu C, Dony L, Kontira A, Fischer D, Roeh S, DiGiaimo R, Cappello S, Theis F, Binder E. S.11.01 Brain organoids as models of the developing human brain: deciphering the molecular signature of prenatal stress European Neuropsychopharmacology. 29: S7-S8. DOI: 10.1016/j.euroneuro.2019.09.032  0.121
2024 Krontira AC, Cruceanu C, Dony L, Kyrousi C, Link MH, Rek N, Pöhlchen D, Raimundo C, Penner-Goeke S, Schowe A, Czamara D, Lahti-Pulkkinen M, Sammallahti S, Wolford E, Heinonen K, ... ... Binder EB, et al. Human cortical neurogenesis is altered via glucocorticoid-mediated regulation of ZBTB16 expression. Neuron. PMID 38442714 DOI: 10.1016/j.neuron.2024.02.005  0.12
2024 Panagiotaropoulou G, Hellberg KG, Coleman JRI, Seok D, Kalman J, Mitchell PB, Schofield PR, Forstner AJ, Bauer M, Scott LJ, Pato CN, Pato MT, Li QS, Kirov G, Landén M, ... ... Binder EB, et al. Identifying genetic differences between bipolar disorder and major depression through multiple GWAS. Medrxiv : the Preprint Server For Health Sciences. PMID 38410442 DOI: 10.1101/2024.01.29.24301816  0.12
2024 Großmann NL, Weihs A, Kühn L, Sauer S, Röh S, Wiechmann T, Rex-Haffner M, Völzke H, Völker U, Binder EB, Teumer A, Homuth G, Klinger-König J, Grabe HJ. Methylation Patterns of the FKBP5 Gene in Association with Childhood Maltreatment and Depressive Disorders. International Journal of Molecular Sciences. 25. PMID 38338761 DOI: 10.3390/ijms25031485  0.12
2024 Yusupov N, Roeh S, Sotillos Elliott L, Chang S, Loganathan S, Urbina-Treviño L, Fröhlich AS, Sauer S, Ködel M, Matosin N, Czamara D, Deussing JM, Binder EB. DNA methylation patterns of FKBP5 regulatory regions in brain and blood of humanized mice and humans. Molecular Psychiatry. PMID 38317011 DOI: 10.1038/s41380-024-02430-x  0.12
1982 Binder E, Holopainen E, Malmberg H, Salo O. Anamnestic data in allergic rhinitis. Allergy. 37: 389-96. PMID 6890320  0.119
2013 Binder E, Edelbauer M. Use of biomarkers in the management of children with lupus. Current Rheumatology Reports. 15: 312. PMID 23355230 DOI: 10.1007/s11926-012-0312-0  0.116
1983 Malmberg H, Holopainen E, Grahne B, Binder E, Savolainen S, Sundberg S. Astemizole in the treatment of hay fever. Allergy. 38: 227-31. PMID 6408940  0.116
1983 Malmberg H, Grahne B, Holopainen E, Binder E. Ipratropium (Atrovent) in the treatment of vasomotor rhinitis of elderly patients. Clinical Otolaryngology and Allied Sciences. 8: 273-6. PMID 6228347  0.115
2021 Kyrousi C, O'Neill AC, Brazovskaja A, He Z, Kielkowski P, Coquand L, Di Giaimo R, D' Andrea P, Belka A, Forero Echeverry A, Mei D, Lenge M, Cruceanu C, Buchsbaum IY, Khattak S, ... ... Binder E, et al. Extracellular LGALS3BP regulates neural progenitor position and relates to human cortical complexity. Nature Communications. 12: 6298. PMID 34728600 DOI: 10.1038/s41467-021-26447-w  0.115
2004 Ising M, Binder E, Brunner J, Fuchs B, Kern N, Künzel H, Majer M, Nickel T, Pfennig A, Modell S, Holsboer F. Subsyndromal AMDP scales to distinguish pathogenetically homogenous subgroups of affective disorders Pharmacopsychiatry. 36. DOI: 10.1055/S-2003-825388  0.111
2009 Brunner J, Freund M, Prelog M, Binder E, Sailer-Hoeck M, Jungraithmayr T, Huemer C, Sergi C, Zimmerhackl LB. Successful treatment of severe juvenile microscopic polyangiitis with rituximab. Clinical Rheumatology. 28: 997-9. PMID 19390907 DOI: 10.1007/s10067-009-1177-0  0.11
2004 Ising M, Adena S, Pfennig A, Binder E, Kern N, Huber J, Modell S, Holsboer F. Munich Vulnerability Study – Familial vulnerability for affective disorders: Search for endophenotypes Pharmacopsychiatry. 36. DOI: 10.1055/S-2003-825387  0.108
2015 Menke A, Arloth J, Best J, Rex-Haffner M, Holsboer F, Uhr M, Binder E. P.1.e.016 Dexamethasone plasma levels impact glucocorticoid receptors-challenge tests for detection of HPA-axis alterations European Neuropsychopharmacology. 25: S218. DOI: 10.1016/S0924-977X(15)30229-7  0.108
2008 Erhardt A, Lucae S, Kern N, Unschuld PG, Ising M, Lieb R, Uhr M, Hohoff C, Deckert J, Bandelow B, Maier W, Binder EB, Müller-Myhsok B, Keck ME, Holsboer F. Association of polymorphisms in the angiotensin-converting enzyme gene with syndromal panic attacks. Molecular Psychiatry. 13: 242-3. PMID 18285758 DOI: 10.1038/Sj.Mp.4002094  0.104
2018 Binder EB. The importance of understanding the biological mechanisms of trauma. Acta Psychiatrica Scandinavica. 134: 279-80. PMID 27598382 DOI: 10.1111/acps.12635  0.103
2005 Wochnik G, Binder E, Salyakina D, Kohli M, Kloiber S, Holsboer F, Rein T. The Role of FKBP51 in the regulation of the glucocorticoid receptor Pharmacopsychiatry. 38. DOI: 10.1055/S-2005-918877  0.102
2013 Kshirsagar S, Binder E, Riedl M, Wechselberger G, Steichen E, Edelbauer M. Enhanced activity of Akt in Teff cells from children with lupus nephritis is associated with reduced induction of tumor necrosis factor receptor-associated factor 6 and increased OX40 expression. Arthritis and Rheumatism. 65: 2996-3006. PMID 23896866 DOI: 10.1002/art.38089  0.101
2021 Binder EB. Genotype-Phenotype Predictions in Autism: Are We There Yet? The American Journal of Psychiatry. 178: 11-12. PMID 33384006 DOI: 10.1176/appi.ajp.2020.20111589  0.098
2004 Ohl F, Binder E, Rödel A, Weißenbacher P, Keck M. ENU-mouse mutagenesis screen: In search of animal models of psychiatric disorders Pharmacopsychiatry. 36. DOI: 10.1055/S-2003-827090  0.097
2022 Dieckmann L, Cruceanu C, Lahti-Pulkkinen M, Lahti J, Kvist T, Laivuori H, Sammallahti S, Villa PM, Suomalainen-König S, Rancourt RC, Plagemann A, Henrich W, Eriksson JG, Kajantie E, Entringer S, ... ... Binder EB, et al. Reliability of a novel approach for reference-based cell type estimation in human placental DNA methylation studies. Cellular and Molecular Life Sciences : Cmls. 79: 115. PMID 35113241 DOI: 10.1007/s00018-021-04091-3  0.097
2004 Brunner J, Ising M, Binder E, Künzel H, Nickel T, Pfennig A, Kern N, Fuchs B, Majer M, Holsboer F, Modell S. Prediction of response to antidepressant monotherapy Pharmacopsychiatry. 36. DOI: 10.1055/S-2003-825284  0.093
2023 Binder EB. New Insights Into Suicidal Behavior From Large Multi-Ancestry Genetic Meta-Analysis. The American Journal of Psychiatry. 180: 705-707. PMID 37777855 DOI: 10.1176/appi.ajp.20230610  0.091
2001 Ohl F, Sillaber I, Binder E, Keck ME, Holsboer F. Differential analysis of behavior and diazepam-induced alterations in C57BL/6N and BALB/c mice using the modified hole board test. Journal of Psychiatric Research. 35: 147-54. PMID 11461710 DOI: 10.1016/S0022-3956(01)00017-6  0.089
2021 Irmscher S, Zipfel SLH, Halder LD, Ivanov L, Gonzalez-Delgado A, Waldeyer C, Seiffert M, Brunner FJ, von der Heide M, Löschmann I, Wulf S, Czamara D, Papac-Milicevic N, Strauß O, Lorkowski S, ... ... Binder EB, et al. Factor H-related protein 1 (FHR-1) is associated with atherosclerotic cardiovascular disease. Scientific Reports. 11: 22511. PMID 34795372 DOI: 10.1038/s41598-021-02011-w  0.089
2010 Potzner MR, Tsarovina K, Binder E, Penzo-Méndez A, Lefebvre V, Rohrer H, Wegner M, Sock E. Sequential requirement of Sox4 and Sox11 during development of the sympathetic nervous system. Development (Cambridge, England). 137: 775-84. PMID 20147379 DOI: 10.1242/dev.042101  0.088
2016 Binder E, Loinger M, Mühlbacher A, Edlinger M, Steichen E, Meraner D, Loacker L, Weigel G, Müller T, Fröhlich-Reiterer E, Hofer SE. Genotyping of coeliac-specific human leucocyte antigen in children with type 1 diabetes: does this screening method make sense? Archives of Disease in Childhood. PMID 28039141 DOI: 10.1136/archdischild-2016-311610  0.087
2006 Papac-Milicevic N, Ryban L, Zaujec J, Binder C, Breuss J, Binder E, Uhrin P, Binder B. Th-W60:8 The interferon inducible gene 12, a novel factor modulating the vascular response to injury Atherosclerosis Supplements. 7: 488. DOI: 10.1016/S1567-5688(06)81949-5  0.086
2004 Binder E, Droste SK, Ohl F, Reul JM. Regular voluntary exercise reduces anxiety-related behaviour and impulsiveness in mice. Behavioural Brain Research. 155: 197-206. PMID 15364478 DOI: 10.1016/j.bbr.2004.04.017  0.085
2011 Altmann A, Weber P, Quast C, Rex-Haffner M, Binder EB, Müller-Myhsok B. vipR: variant identification in pooled DNA using R. Bioinformatics (Oxford, England). 27: i77-84. PMID 21685105 DOI: 10.1093/bioinformatics/btr205  0.085
2015 Moser C, Maurer K, Binder E, Meraner D, Steichen E, Abt D, Freund-Unsinn K, Hofer SE. Needle detachment in a slim and physically active child with insulin pump treatment. Pediatric Diabetes. PMID 26201949 DOI: 10.1111/pedi.12297  0.085
2021 Schmid KT, Höllbacher B, Cruceanu C, Böttcher A, Lickert H, Binder EB, Theis FJ, Heinig M. scPower accelerates and optimizes the design of multi-sample single cell transcriptomic studies. Nature Communications. 12: 6625. PMID 34785648 DOI: 10.1038/s41467-021-26779-7  0.082
2011 Catania C, Binder E, Cota D. mTORC1 signaling in energy balance and metabolic disease. International Journal of Obesity (2005). 35: 751-61. PMID 20877289 DOI: 10.1038/Ijo.2010.208  0.082
1989 Malmberg H, Binder E, Fräki J, Harvima I, Salo O, Holopainen E. Nasal reactions elicited by unilateral allergen challenge. Acta Oto-Laryngologica. 107: 446-9. PMID 2474232  0.08
2014 Binder E, Griesmaier E, Giner T, Sailer-Höck M, Brunner J. Kawasaki disease in children and adolescents: clinical data of Kawasaki patients in a western region (Tyrol) of Austria from 2003-2012. Pediatric Rheumatology Online Journal. 12: 37. PMID 27643389 DOI: 10.1186/1546-0096-12-37  0.079
2014 Binder E, Griesmaier E, Giner T, Sailer-Höck M, Brunner J. Kawasaki disease in children and adolescents: clinical data of Kawasaki patients in a western region (Tyrol) of Austria from 2003-2012. Pediatric Rheumatology Online Journal. 12: 37. PMID 27643389 DOI: 10.1186/1546-0096-12-37  0.079
1984 Binder E, Holopainen E, Malmberg H, Salo OP. Clinical findings in patients with allergic rhinitis. Rhinology. 22: 255-60. PMID 6522975  0.078
2009 Rüdiger R, Binder E, Tsarovina K, Schmidt M, Reiff T, Stubbusch J, Rohrer H. In vivo role for CREB signaling in the noradrenergic differentiation of sympathetic neurons. Molecular and Cellular Neurosciences. 42: 142-51. PMID 19545628 DOI: 10.1016/J.Mcn.2009.06.007  0.078
2012 Pelzer E, Pauls AK, Binder E, Brunn A, Fink GR, Timmermann L. Deep brain stimulation in rapidly progressive Parkinson-dystonia syndrome due to mitochondrial disorder. Parkinsonism & Related Disorders. 18: 672-4. PMID 22104013 DOI: 10.1016/J.Parkreldis.2011.10.012  0.077
2003 Ohl F, Roedel A, Binder E, Holsboer F. Impact of high and low anxiety on cognitive performance in a modified hole board test in C57BL/6 and DBA/2 mice. The European Journal of Neuroscience. 17: 128-36. PMID 12534976 DOI: 10.1046/J.1460-9568.2003.02436.X  0.07
2015 Sämann P, Zannas A, Carrillo T, Binder E. Structural MR correlates of epigenetic age acceleration Pharmacopsychiatry. 48. DOI: 10.1055/S-0035-1557993  0.07
2014 Dettmar AK, Binder E, Greiner FR, Liebau MC, Kurschat CE, Jungraithmayr TC, Saleem MA, Schmitt CP, Feifel E, Orth-Höller D, Kemper MJ, Pepys M, Würzner R, Oh J. Protection of human podocytes from shiga toxin 2-induced phosphorylation of mitogen-activated protein kinases and apoptosis by human serum amyloid P component. Infection and Immunity. 82: 1872-9. PMID 24566618 DOI: 10.1128/IAI.01591-14  0.069
2019 Martinelli S, Wiechmann T, Kathrin H, Meinhold L, Roeh S, Sauer S, Gassen N, Binder E. P.1.27 Unravelling the differential role of FKBP51 (FK506 Binding Protein 5) isoforms in different cellular pathways European Neuropsychopharmacology. 29: S652-S653. DOI: 10.1016/j.euroneuro.2019.01.029  0.064
2015 Binder E, Lange O, Edlinger M, Meraner D, Abt D, Moser C, Steichen E, Hofer SE. Frequency of dermatological side effects of continuous subcutaneous insulin infusion in children and adolescents with type 1 diabetes. Experimental and Clinical Endocrinology & Diabetes : Official Journal, German Society of Endocrinology [and] German Diabetes Association. 123: 260-4. PMID 25607337 DOI: 10.1055/s-0034-1394381  0.061
2018 Binder E, Rohrer T, Denzer C, Marg W, Ohlenschläger U, Schenk-Huber H, Schierloh U, Skopnik H, Fröhlich-Reiterer EE, Holl RW, Prinz N. Screening for coeliac disease in 1624 mainly asymptomatic children with type 1 diabetes: is genotyping for coeliac-specific human leucocyte antigen the right approach? Archives of Disease in Childhood. PMID 30327331 DOI: 10.1136/archdischild-2018-315549  0.059
2014 Pauls KA, Hammesfahr S, Moro E, Moore AP, Binder E, El Majdoub F, Fink GR, Sturm V, Krauss JK, Maarouf M, Timmermann L. Deep brain stimulation in the ventrolateral thalamus/subthalamic area in dystonia with head tremor. Movement Disorders : Official Journal of the Movement Disorder Society. 29: 953-9. PMID 24752968 DOI: 10.1002/mds.25884  0.058
2009 Krämer S, Binder E, Loof T, Wang-Rosenke Y, Martini S, Khadzhynov D, Budde K, Neumayer HH, Peters H. The lymphocyte migration inhibitor FTY720 attenuates experimental hypertensive nephropathy. American Journal of Physiology. Renal Physiology. 297: F218-27. PMID 19439518 DOI: 10.1152/ajprenal.90617.2008  0.057
2015 Zimmermann CA, Hoffmann A, Binder EB, Spengler D. Differences in Histone Modifications Between Individuals Personalized Epigenetics. 55-82. DOI: 10.1016/B978-0-12-420135-4.00003-6  0.057
2016 Reinauer C, Meissner T, Roden M, Thon A, Holterhus PM, Haberland H, Binder E, Marg W, Bollow E, Holl R. Low prevalence of patients with mitochondrial disease in the German/Austrian DPV diabetes registry. European Journal of Pediatrics. 175: 613-22. PMID 26670026 DOI: 10.1007/s00431-015-2675-5  0.057
2008 Krämer S, Wang-Rosenke Y, Scholl V, Binder E, Loof T, Khadzhynov D, Kawachi H, Shimizu F, Diekmann F, Budde K, Neumayer HH, Peters H. Low-dose mTOR inhibition by rapamycin attenuates progression in anti-thy1-induced chronic glomerulosclerosis of the rat. American Journal of Physiology. Renal Physiology. 294: F440-9. PMID 18094032 DOI: 10.1152/ajprenal.00379.2007  0.056
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