Daniel A. KIRSCHNER - Publications

Affiliations: 
Boston College, Newton, MA, United States 
Area:
membrane structure; x-ray diffraction; neutron diffraction; myelin; amyloid

123 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2022 Baumann A, Denninger AR, Domin M, Demé B, Kirschner DA. Metabolically-incorporated deuterium in myelin localized by neutron diffraction and identified by mass spectrometry. Current Research in Structural Biology. 4: 231-245. PMID 35941866 DOI: 10.1016/j.crstbi.2022.06.003  0.81
2020 Visigalli D, Capodivento G, Basit A, Fernández R, Hamid Z, Pencová B, Gemelli C, Marubbi D, Pastorino C, Luoma AM, Riekel C, Kirschner DA, Schenone A, Fernández JA, Armirotti A, et al. Exploiting Sphingo- and Glycerophospholipid Impairment to Select Effective Drugs and Biomarkers for CMT1A. Frontiers in Neurology. 11: 903. PMID 32982928 DOI: 10.3389/Fneur.2020.00903  0.458
2017 Inouye H, Kuo FH, Denninger AR, Weinhausen B, Burghammer M, Kirschner DA. Myelin structure in unfixed, single nerve fibers: Scanning x-ray microdiffraction with a beam size of 200 nm. Journal of Structural Biology. PMID 28698109 DOI: 10.1016/J.Jsb.2017.07.001  0.815
2016 Ahmed SS, Schattgen SA, Frakes AE, Sikoglu EM, Su Q, Li J, Hampton TG, Denninger AR, Kirschner DA, Kaspar B, Matalon R, Gao G. rAAV gene therapy in a Canavan's disease mouse model reveals immune impairments and an extended pathology beyond the central nervous system. Molecular Therapy : the Journal of the American Society of Gene Therapy. PMID 27039844 DOI: 10.1038/Mt.2016.68  0.758
2015 Inouye H, Kirschner DA. Evolution of myelin ultrastructure and the major structural myelin proteins. Brain Research. PMID 26519753 DOI: 10.1016/j.brainres.2015.10.037  0.464
2015 Denninger AR, Breglio A, Maheras KJ, LeDuc G, Cristiglio V, Demé B, Gow A, Kirschner DA. Claudin-11 Tight Junctions in Myelin Are a Barrier to Diffusion and Lack Strong Adhesive Properties. Biophysical Journal. 109: 1387-97. PMID 26445439 DOI: 10.1016/J.Bpj.2015.08.012  0.825
2015 Luoma AM, Kuo F, Cakici O, Crowther MN, Denninger AR, Avila RL, Brites P, Kirschner DA. Plasmalogen phospholipids protect internodal myelin from oxidative damage. Free Radical Biology & Medicine. 84: 296-310. PMID 25801291 DOI: 10.1016/J.Freeradbiomed.2015.03.012  0.81
2015 Heinecke KA, Luoma A, d'Azzo A, Kirschner DA, Seyfried TN. Myelin abnormalities in the optic and sciatic nerves in mice with GM1-gangliosidosis. Asn Neuro. 7. PMID 25694553 DOI: 10.1177/1759091415568913  0.324
2014 Denninger AR, Demé B, Cristiglio V, LeDuc G, Feller WB, Kirschner DA. Neutron scattering from myelin revisited: bilayer asymmetry and water-exchange kinetics. Acta Crystallographica. Section D, Biological Crystallography. 70: 3198-211. PMID 25478838 DOI: 10.1107/S1399004714023815  0.837
2014 Inouye H, Liu J, Makowski L, Palmisano M, Burghammer M, Riekel C, Kirschner DA. Myelin organization in the nodal, paranodal, and juxtaparanodal regions revealed by scanning x-ray microdiffraction. Plos One. 9: e100592. PMID 24984037 DOI: 10.1371/journal.pone.0100592  0.424
2014 Krishnan R, Tsubery H, Proschitsky MY, Asp E, Lulu M, Gilead S, Gartner M, Waltho JP, Davis PJ, Hounslow AM, Kirschner DA, Inouye H, Myszka DG, Wright J, Solomon B, et al. A bacteriophage capsid protein provides a general amyloid interaction motif (GAIM) that binds and remodels misfolded protein assemblies. Journal of Molecular Biology. 426: 2500-19. PMID 24768993 DOI: 10.1016/J.Jmb.2014.04.015  0.304
2014 da Silva TF, Eira J, Lopes AT, Malheiro AR, Sousa V, Luoma A, Avila RL, Wanders RJ, Just WW, Kirschner DA, Sousa MM, Brites P. Peripheral nervous system plasmalogens regulate Schwann cell differentiation and myelination. The Journal of Clinical Investigation. 124: 2560-70. PMID 24762439 DOI: 10.1172/Jci72063  0.754
2013 Ahmed SS, Li H, Cao C, Sikoglu EM, Denninger AR, Su Q, Eaton S, Liso Navarro AA, Xie J, Szucs S, Zhang H, Moore C, Kirschner DA, Seyfried TN, Flotte TR, et al. A single intravenous rAAV injection as late as P20 achieves efficacious and sustained CNS Gene therapy in Canavan mice. Molecular Therapy : the Journal of the American Society of Gene Therapy. 21: 2136-47. PMID 23817205 DOI: 10.1038/Mt.2013.138  0.783
2012 Patzkó A, Bai Y, Saporta MA, Katona I, Wu X, Vizzuso D, Feltri ML, Wang S, Dillon LM, Kamholz J, Kirschner D, Sarkar FH, Wrabetz L, Shy ME. Curcumin derivatives promote Schwann cell differentiation and improve neuropathy in R98C CMT1B mice. Brain : a Journal of Neurology. 135: 3551-66. PMID 23250879 DOI: 10.1093/Brain/Aws299  0.378
2012 Gilardini A, Avila RL, Oggioni N, Rodriguez-Menendez V, Bossi M, Canta A, Cavaletti G, Kirschner DA. Myelin structure is unaltered in chemotherapy-induced peripheral neuropathy. Neurotoxicology. 33: 1-7. PMID 22079976 DOI: 10.1016/J.Neuro.2011.10.010  0.768
2010 Rasi K, Hurskainen M, Kallio M, Stavén S, Sormunen R, Heape AM, Avila RL, Kirschner D, Muona A, Tolonen U, Tanila H, Huhtala P, Soininen R, Pihlajaniemi T. Lack of collagen XV impairs peripheral nerve maturation and, when combined with laminin-411 deficiency, leads to basement membrane abnormalities and sensorimotor dysfunction. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 30: 14490-501. PMID 20980607 DOI: 10.1523/Jneurosci.2644-10.2010  0.758
2010 Avila RL, D'Antonio M, Bachi A, Inouye H, Feltri ML, Wrabetz L, Kirschner DA. P0 (protein zero) mutation S34C underlies instability of internodal myelin in S63C mice. The Journal of Biological Chemistry. 285: 42001-12. PMID 20937820 DOI: 10.1074/Jbc.M110.166967  0.787
2010 Inouye H, Gleason KA, Zhang D, Decatur SM, Kirschner DA. Differential effects of Phe19 and Phe20 on fibril formation by amyloidogenic peptide A beta 16-22 (Ac-KLVFFAE-NH2). Proteins. 78: 2306-21. PMID 20544966 DOI: 10.1002/Prot.22743  0.334
2010 Kirschner DA, Avila RL, Gamez Sazo RE, Luoma A, Enzmann GU, Agrawal D, Inouye H, Bunge MB, Kocsis J, Peters A, Whittemore SR. Rapid assessment of internodal myelin integrity in central nervous system tissue. Journal of Neuroscience Research. 88: 712-21. PMID 19795370 DOI: 10.1002/Jnr.22241  0.745
2009 Verheijen MH, Camargo N, Verdier V, Nadra K, de Preux Charles AS, Médard JJ, Luoma A, Crowther M, Inouye H, Shimano H, Chen S, Brouwers JF, Helms JB, Feltri ML, Wrabetz L, ... Kirschner D, et al. SCAP is required for timely and proper myelin membrane synthesis. Proceedings of the National Academy of Sciences of the United States of America. 106: 21383-8. PMID 19948958 DOI: 10.1073/Pnas.0905633106  0.513
2009 Agrawal D, Hawk R, Avila RL, Inouye H, Kirschner DA. Internodal myelination during development quantitated using X-ray diffraction. Journal of Structural Biology. 168: 521-6. PMID 19576284 DOI: 10.1016/J.Jsb.2009.06.019  0.776
2009 Koellhoffer EC, Inouye H, Kirschner DA. Successful de novo conversion from [psi−] to [PSI+] Saccharomyces cerevisiae Biophysical Journal. 96: 91a. DOI: 10.1016/J.Bpj.2008.12.379  0.313
2009 Crowther M, Shy B, Luoma AM, Wrabetz L, Shy ME, Kirschner DA. Myelin Structural Integrity in a Model for Human Early-Onset CMT1B Biophysical Journal. 96: 461a. DOI: 10.1016/J.Bpj.2008.12.2371  0.589
2008 Kirschner DA, Karthigesan J, Bizzozero OA, Kosaras B, Inouye H. Myelin structure and composition of myelinated tissue in the African lungfish. Neuron Glia Biology. 4: 59-70. PMID 19737430 DOI: 10.1017/S1740925X09990196  0.498
2008 Flores AI, Narayanan SP, Morse EN, Shick HE, Yin X, Kidd G, Avila RL, Kirschner DA, Macklin WB. Constitutively active Akt induces enhanced myelination in the CNS. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 28: 7174-83. PMID 18614687 DOI: 10.1523/Jneurosci.0150-08.2008  0.765
2008 Luo X, Cerullo J, Dawli T, Priest C, Haddadin Z, Kim A, Inouye H, Suffoletto BP, Avila RL, Lees JPB, Sharma D, Xie B, Costello CE, Kirschner DA. Peripheral myelin of Xenopus laevis: Role of electrostatic and hydrophobic interactions in membrane compaction Journal of Structural Biology. 162: 170-183. PMID 18065238 DOI: 10.1016/J.Jsb.2007.10.012  0.816
2007 Xie B, Luo X, Zhao C, Priest CM, Chan SY, O' Connor PB, Kirschner DA, Costello CE. Molecular Characterization of Myelin Protein Zero in Xenopus laevis Peripheral Nerve: Equilibrium between Non-covalently Associated Dimer and Monomer. International Journal of Mass Spectrometry. 268: 304-315. PMID 19430539 DOI: 10.1016/J.Ijms.2007.08.007  0.662
2007 Luo X, Inouye H, Gross AA, Hidalgo MM, Sharma D, Lee D, Avila RL, Salmona M, Kirschner DA. Cytoplasmic domain of zebrafish myelin protein zero: adhesive role depends on beta-conformation. Biophysical Journal. 93: 3515-28. PMID 17693467 DOI: 10.1529/Biophysj.107.112771  0.793
2007 McNally MA, Baek RC, Avila RL, Seyfried TN, Strichartz GR, Kirschner DA. Peripheral nervous system manifestations in a Sandhoff disease mouse model: nerve conduction, myelin structure, lipid analysis. Journal of Negative Results in Biomedicine. 6: 8. PMID 17623103 DOI: 10.1186/1477-5751-6-8  0.786
2007 Luo X, Sharma D, Inouye H, Lee D, Avila RL, Salmona M, Kirschner DA. Cytoplasmic domain of human myelin protein zero likely folded as beta-structure in compact myelin. Biophysical Journal. 92: 1585-97. PMID 17142269 DOI: 10.1529/Biophysj.106.094722  0.812
2007 Avila RL, Tevlin BR, Lees JP, Inouye H, Kirschner DA. Myelin structure and composition in zebrafish. Neurochemical Research. 32: 197-209. PMID 16951904 DOI: 10.1007/S11064-006-9136-5  0.786
2007 Xie B, Luo X, Zhao C, Priest CM, Chan SY, O'Connor PB, Kirschner DA, Costello CE. Molecular characterization of myelin protein zero in Xenopus laevis peripheral nerve: Equilibrium between non-covalently associated dimer and monomer International Journal of Mass Spectrometry. 268: 304-315. DOI: 10.1016/j.ijms.2007.08.007  0.646
2006 Inouye H, Kirschner DA. X-Ray fiber and powder diffraction of PrP prion peptides. Advances in Protein Chemistry. 73: 181-215. PMID 17190614 DOI: 10.1016/S0065-3233(06)73006-6  0.337
2006 Wrabetz L, D'Antonio M, Pennuto M, Dati G, Tinelli E, Fratta P, Previtali S, Imperiale D, Zielasek J, Toyka K, Avila RL, Kirschner DA, Messing A, Feltri ML, Quattrini A. Different intracellular pathomechanisms produce diverse Myelin Protein Zero neuropathies in transgenic mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 26: 2358-68. PMID 16495463 DOI: 10.1523/Jneurosci.3819-05.2006  0.774
2006 Yin X, Baek RC, Kirschner DA, Peterson A, Fujii Y, Nave KA, Macklin WB, Trapp BD. Evolution of a neuroprotective function of central nervous system myelin. The Journal of Cell Biology. 172: 469-78. PMID 16449196 DOI: 10.1083/Jcb.200509174  0.488
2005 Avila RL, Inouye H, Baek RC, Yin X, Trapp BD, Feltri ML, Wrabetz L, Kirschner DA. Structure and stability of internodal myelin in mouse models of hereditary neuropathy. Journal of Neuropathology and Experimental Neurology. 64: 976-90. PMID 16254492 DOI: 10.1097/01.Jnen.0000186925.95957.Dc  0.788
2005 Sharma D, Shinchuk LM, Inouye H, Wetzel R, Kirschner DA. Polyglutamine homopolymers having 8-45 residues form slablike beta-crystallite assemblies. Proteins. 61: 398-411. PMID 16114051 DOI: 10.1002/Prot.20602  0.388
2005 Shinchuk LM, Sharma D, Blondelle SE, Reixach N, Inouye H, Kirschner DA. Poly-(L-alanine) expansions form core beta-sheets that nucleate amyloid assembly. Proteins. 61: 579-89. PMID 16114037 DOI: 10.1002/Prot.20536  0.331
2005 Baxa U, Cheng N, Winkler DC, Chiu TK, Davies DR, Sharma D, Inouye H, Kirschner DA, Wickner RB, Steven AC. Filaments of the Ure2p prion protein have a cross-beta core structure. Journal of Structural Biology. 150: 170-9. PMID 15866740 DOI: 10.1016/J.Jsb.2005.02.007  0.35
2004 Goux WJ, Kopplin L, Nguyen AD, Leak K, Rutkofsky M, Shanmuganandam VD, Sharma D, Inouye H, Kirschner DA. The formation of straight and twisted filaments from short tau peptides. The Journal of Biological Chemistry. 279: 26868-75. PMID 15100221 DOI: 10.1074/Jbc.M402379200  0.302
2004 Tagliavini F, Morbin M, Colombo L, Mazzoleni G, Capobianco R, Diomede L, Kirschner DA, Forloni G, Salmona M. P3-357 Structural properties of gerstmann-Sträussler-Scheinker disease amyloid protein Neurobiology of Aging. 25. DOI: 10.1016/S0197-4580(04)81506-9  0.311
2003 Bond JP, Deverin SP, Inouye H, el-Agnaf OM, Teeter MM, Kirschner DA. Assemblies of Alzheimer's peptides A beta 25-35 and A beta 31-35: reverse-turn conformation and side-chain interactions revealed by X-ray diffraction. Journal of Structural Biology. 141: 156-70. PMID 12615542 DOI: 10.1016/S1047-8477(02)00625-1  0.3
2003 Inouye H, Kirschner DA. X-ray fibre diffraction analysis of assemblies formed by prion-related peptides: Polymorphism of the heterodimer interface between PrPCand PrPSc Fibre Diffraction Review. 11: 102. DOI: 10.1382/S200311102  0.326
2002 Inouye H, Bond JE, Deverin SP, Lim A, Costello CE, Kirschner DA. Molecular organization of amyloid protofilament-like assembly of betabellin 15D: helical array of beta-sandwiches. Biophysical Journal. 83: 1716-27. PMID 12202394 DOI: 10.1016/S0006-3495(02)73939-8  0.31
2002 Thompson AJ, Cronin MS, Kirschner DA. Myelin protein zero exists as dimers and tetramers in native membranes of Xenopus laevis peripheral nerve. Journal of Neuroscience Research. 67: 766-71. PMID 11891790 DOI: 10.1002/Jnr.10167  0.523
2001 Bond JP, Saavedra RA, Kirschner DA. Expression and purification of the extracellular domain of human myelin protein zero. Protein Expression and Purification. 23: 398-410. PMID 11722176 DOI: 10.1006/Prep.2001.1525  0.502
2000 Kirschner DA, Teplow DB, Damas AM. Twist and sheet: variations on the theme of amyloid Journal of Structural Biology. 130: 87. PMID 10940216 DOI: 10.1006/Jsbi.2000.4293  0.324
2000 Inouye H, Bond J, Baldwin MA, Ball HL, Prusiner SB, Kirschner DA. Structural changes in a hydrophobic domain of the prion protein induced by hydration and by ala-->Val and pro-->Leu substitutions. Journal of Molecular Biology. 300: 1283-96. PMID 10903869 DOI: 10.1006/Jmbi.2000.3926  0.329
2000 Riccio P, Fasano A, Borenshtein N, Bleve-Zacheo T, Kirschner DA. Multilamellar packing of myelin modeled by lipid-bound MBP. Journal of Neuroscience Research. 59: 513-21. PMID 10679790 DOI: 10.1002/(Sici)1097-4547(20000215)59:4<513::Aid-Jnr6>3.0.Co;2-M  0.533
2000 Castillo GM, Kirschner DA, Yee AG, Snow AD. Electron microscopy and X-ray diffraction studies further confirm the efficacy of PTI-000703™ (Cat's claw derivative) as a potent inhibitor of Alzheimer's beta-amyloid protein fibrillogenesis Neurobiology of Aging. 21: 58. DOI: 10.1016/S0197-4580(00)82486-0  0.31
1999 Peled S, Cory DG, Raymond SA, Kirschner DA, Jolesz FA. Water diffusion, T(2), and compartmentation in frog sciatic nerve. Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine. 42: 911-8. PMID 10542350 DOI: 10.1002/(Sici)1522-2594(199911)42:5<911::Aid-Mrm11>3.0.Co;2-J  0.361
1999 Winkler S, Szela S, Avtges P, Valluzzi R, Kirschner DA, Kaplan D. Designing recombinant spider silk proteins to control assembly. International Journal of Biological Macromolecules. 24: 265-70. PMID 10342773 DOI: 10.1016/S0141-8130(98)00088-9  0.32
1999 Inouye H, Tsuruta H, Sedzik J, Uyemura K, Kirschner DA. Tetrameric assembly of full-sequence protein zero myelin glycoprotein by synchrotron x-ray scattering. Biophysical Journal. 76: 423-37. PMID 9876154 DOI: 10.1016/S0006-3495(99)77209-7  0.362
1998 Kirschner DA, Elliott-Bryant R, Szumowski KE, Gonnerman WA, Kindy MS, Sipe JD, Cathcart ES. In vitro amyloid fibril formation by synthetic peptides corresponding to the amino terminus of apoSAA isoforms from amyloid-susceptible and amyloid-resistant mice. Journal of Structural Biology. 124: 88-98. PMID 9931277 DOI: 10.1006/Jsbi.1998.4047  0.315
1998 Inouye H, Domingues FS, Damas AM, Saraiva MJ, Lundgren E, Sandgren O, Kirschner DA. Analysis of x-ray diffraction patterns from amyloid of biopsied vitreous humor and kidney of transthyretin (TTR) Met30 familial amyloidotic polyneuropathy (FAP) patients: axially arrayed TTR monomers constitute the protofilament. Amyloid : the International Journal of Experimental and Clinical Investigation : the Official Journal of the International Society of Amyloidosis. 5: 163-74. PMID 9818053 DOI: 10.3109/13506129809003842  0.348
1998 Inouye H, Kirschner DA. Polypeptide chain folding in the hydrophobic core of hamster scrapie prion: analysis by X-ray diffraction. Journal of Structural Biology. 122: 247-55. PMID 9724626 DOI: 10.1006/Jsbi.1998.3998  0.321
1998 Malinchik SB, Inouye H, Szumowski KE, Kirschner DA. Structural analysis of Alzheimer's beta(1-40) amyloid: protofilament assembly of tubular fibrils. Biophysical Journal. 74: 537-45. PMID 9449354 DOI: 10.1016/S0006-3495(98)77812-9  0.316
1997 Inouye H, Kirschner DA. X-ray diffraction analysis of scrapie prion: intermediate and folded structures in a peptide containing two putative alpha-helices. Journal of Molecular Biology. 268: 375-89. PMID 9159477 DOI: 10.1006/Jmbi.1997.0949  0.346
1996 Kirschner DA, Szumowski K, Gabreëls-Festen AA, Hoogendijk JE, Bolhuis PA. Inherited demyelinating peripheral neuropathies: relating myelin packing abnormalities to P0 molecular defects. Journal of Neuroscience Research. 46: 502-8. PMID 8950710 DOI: 10.1002/(Sici)1097-4547(19961115)46:4<502::Aid-Jnr12>3.0.Co;2-#  0.553
1996 Kirschner DA, Inouye H, Saavedra RA. Membrane adhesion in peripheral myelin: good and bad wraps with protein P0. Structure (London, England : 1993). 4: 1239-44. PMID 8939762 DOI: 10.1016/S0969-2126(96)00132-3  0.526
1996 Karthigasan J, Garvey JS, Ramamurthy GV, Kirschner DA. Immunolocalization of 17 and 21.5 kDa MBP isoforms in compact myelin and radial component. Journal of Neurocytology. 25: 1-7. PMID 8852934 DOI: 10.1007/Bf02284781  0.52
1996 Karthigasan J, Evans EL, Vouyiouklis DA, Inouye H, Borenshteyn N, Ramamurthy GV, Kirschner DA. Effects of rumpshaker mutation on CNS myelin composition and structure. Journal of Neurochemistry. 66: 338-45. PMID 8522972 DOI: 10.1046/J.1471-4159.1996.66010338.X  0.573
1995 Billings-Gagliardi S, Kirschner DA, Nadon NL, DiBenedetto LM, Karthigasan J, Lane P, Pearsall GB, Wolf MK. Jimpy 4J: a new X-linked mouse mutation producing severe CNS hypomyelination. Developmental Neuroscience. 17: 300-10. PMID 8829919 DOI: 10.1159/000111300  0.389
1995 Karthigasan J, Inouye H, Kirschner DA. Implications of the sequence similarities between tau and myelin basic protein. Medical Hypotheses. 45: 235-40. PMID 8569545 DOI: 10.1016/0306-9877(95)90111-6  0.431
1995 Nguyen JT, Inouye H, Baldwin MA, Fletterick RJ, Cohen FE, Prusiner SB, Kirschner DA. X-ray diffraction of scrapie prion rods and PrP peptides. Journal of Molecular Biology. 252: 412-22. PMID 7563061 DOI: 10.1006/Jmbi.1995.0507  0.306
1995 Billings-Gagliardi S, Kirschner DA, Nadon NL, DiBenedetto LM, Karthigasan J, Lane P, Pearsall GB, Wolf MK. Jimpy 4J: A New X-Linked Mouse Mutation Producing Severe CNS Hypomyelination (Part 2 of 2) Developmental Neuroscience. 17: 306-310. DOI: 10.1159/000315764  0.389
1994 Karthigasan J, Kosaras B, Nguyen J, Kirschner DA. Protein and lipid composition of radial component-enriched CNS myelin. Journal of Neurochemistry. 62: 1203-13. PMID 8113804 DOI: 10.1046/J.1471-4159.1994.62031203.X  0.535
1994 Kirschner DA, Eichberg J. Restricted hypotonic swelling of peripheral nerve myelin in streptozocin-induced diabetic rats. Journal of Neuroscience Research. 38: 142-8. PMID 8078099 DOI: 10.1002/Jnr.490380204  0.474
1994 Fraser PE, McLachlan DR, Surewicz WK, Mizzen CA, Snow AD, Nguyen JT, Kirschner DA. Conformation and fibrillogenesis of Alzheimer A beta peptides with selected substitution of charged residues. Journal of Molecular Biology. 244: 64-73. PMID 7966323 DOI: 10.1006/Jmbi.1994.1704  0.325
1994 Kinney HC, Karthigasan J, Borenshteyn NI, Flax JD, Kirschner DA. Myelination in the developing human brain: biochemical correlates. Neurochemical Research. 19: 983-96. PMID 7800125 DOI: 10.1007/Bf00968708  0.468
1994 Kirschner DA, Saavedra RA. Mutations in demyelinating peripheral neuropathies support molecular model of myelin P0-glycoprotein extracellular domain. Journal of Neuroscience Research. 39: 63-9. PMID 7528817 DOI: 10.1002/Jnr.490390109  0.481
1994 Inouye H, Kirschner DA. Membrane topology of PLP in CNS myelin: evaluation of models. Neurochemical Research. 19: 975-81. PMID 7528356 DOI: 10.1007/Bf00968707  0.449
1994 Montag D, Giese KP, Bartsch U, Martini R, Lang Y, Blüthmann H, Karthigasan J, Kirschner DA, Wintergerst ES, Nave KA. Mice deficient for the myelin-associated glycoprotein show subtle abnormalities in myelin. Neuron. 13: 229-46. PMID 7519026 DOI: 10.1016/0896-6273(94)90472-3  0.551
1993 Fraser PE, Nguyen JT, McLachlan DR, Abraham CR, Kirschner DA. Alpha 1-antichymotrypsin binding to Alzheimer A beta peptides is sequence specific and induces fibril disaggregation in vitro. Journal of Neurochemistry. 61: 298-305. PMID 8515277 DOI: 10.1111/J.1471-4159.1993.Tb03568.X  0.302
1993 Inouye H, Fraser PE, Kirschner DA. Structure of beta-crystallite assemblies formed by Alzheimer beta-amyloid protein analogues: analysis by x-ray diffraction. Biophysical Journal. 64: 502-19. PMID 8457674 DOI: 10.1016/S0006-3495(93)81393-6  0.319
1993 Dhaunsi GS, Singh B, Singh AK, Kirschner DA, Singh I. Thioridazine induces lipid peroxidation in myelin of rat brain. Neuropharmacology. 32: 157-67. PMID 8383815 DOI: 10.1016/0028-3908(93)90096-L  0.395
1993 Wells CA, Saavedra RA, Inouye H, Kirschner DA. Myelin P0-glycoprotein: predicted structure and interactions of extracellular domain. Journal of Neurochemistry. 61: 1987-95. PMID 7504078 DOI: 10.1111/J.1471-4159.1993.Tb07434.X  0.459
1992 Fraser PE, Nguyen JT, Inouye H, Surewicz WK, Selkoe DJ, Podlisny MB, Kirschner DA. Fibril formation by primate, rodent, and Dutch-hemorrhagic analogues of Alzheimer amyloid beta-protein. Biochemistry. 31: 10716-23. PMID 1420187 DOI: 10.1021/Bi00159A011  0.307
1992 Karthigasan J, Bauer TK, Teplow DB, Saavedra RA, Kirschner DA. Phylogenetically conserved amino acids of MBP and P0 from amphibian myelin. Journal of Molecular Neuroscience : Mn. 3: 185-8. PMID 1382532 DOI: 10.1007/Bf03380137  0.444
1992 Sedzik J, Kirschner DA. Is myelin basic protein crystallizable? Neurochemical Research. 17: 157-66. PMID 1371603 DOI: 10.1007/Bf00966794  0.427
1991 Sinclair A, Raz Y, Kirschner DA, Villa-Komaroff L, Wolf MK, Billings-Gagliardi S. Shiverer jimpy double mutant mice. V. Correlation of genotype and myelin proteins. Developmental Neuroscience. 13: 138-42. PMID 1721567 DOI: 10.1159/000112151  0.445
1991 Billings-Gagliardi S, Tosic M, Matthieu JM, Kirschner DA, Wolf MK. Quantitative differences between homozygous 'USA' and 'Swiss' mld mutant mice. Developmental Neuroscience. 13: 87-97. PMID 1712720 DOI: 10.1159/000112145  0.453
1991 Inouye H, Kirschner DA. Folding and function of the myelin proteins from primary sequence data. Journal of Neuroscience Research. 28: 1-17. PMID 1710279 DOI: 10.1002/Jnr.490280102  0.463
1991 Kirschner D, Saavedra R, Inouye H. P0-glycoprotein of myelin: Orientation of its extracellular domain in homophilic adhesion Journal of Neuroimmunology. 35: 153. DOI: 10.1016/0165-5728(91)91128-Y  0.313
1990 Kosaras B, Kirschner DA. Radial component of CNS myelin: junctional subunit structure and supramolecular assembly. Journal of Neurocytology. 19: 187-99. PMID 2113569 DOI: 10.1007/Bf01217297  0.561
1990 Billings-Gagliardi S, Karthigasan J, Kirschner DA, Wolf MK. Quaking*jimpy double mutant mice: additional evidence for independence of primary deficits in jimpy. Brain Research. Molecular Brain Research. 7: 189-98. PMID 1692389 DOI: 10.1016/0169-328X(90)90027-B  0.515
1990 KOSARAS B, KIRSCHNER DA. Fine-Structure and Supramolecular Organization of the Radial Component of CNS Myelin Annals of the New York Academy of Sciences. 605: 430-434. DOI: 10.1111/J.1749-6632.1990.Tb42437.X  0.453
1989 Kirschner DA, Inouye H, Ganser AL, Mann V. Myelin membrane structure and composition correlated: a phylogenetic study. Journal of Neurochemistry. 53: 1599-609. PMID 2795020 DOI: 10.1111/J.1471-4159.1989.Tb08558.X  0.557
1989 Inouye H, Karthigasan J, Kirschner DA. Membrane structure in isolated and intact myelins. Biophysical Journal. 56: 129-37. PMID 2752082 DOI: 10.1016/S0006-3495(89)82658-X  0.544
1989 Brown FR, Karthigasan J, Singh I, Kirschner DA. X-ray diffraction analysis of myelin lipid/proteolipid protein multilayers. Journal of Neuroscience Research. 24: 192-200. PMID 2585547 DOI: 10.1002/Jnr.490240210  0.419
1989 Inouye H, Kirschner DA. Orientation of proteolipid protein in myelin: comparison of models with X-ray diffraction measurements. Developmental Neuroscience. 11: 81-9. PMID 2472943  0.306
1988 Ganser AL, Kerner AL, Brown BJ, Davisson MT, Kirschner DA. A survey of neurological mutant mice. I. Lipid composition of myelinated tissue in known myelin mutants. Developmental Neuroscience. 10: 99-122. PMID 3402360 DOI: 10.1159/000111961  0.483
1988 Ganser AL, Kerner AL, Brown BJ, Davisson MT, Kirschner DA. A survey of neurological mutant mice. II. Lipid composition of myelinated tissue in possible myelin mutants. Developmental Neuroscience. 10: 123-40. PMID 3402356 DOI: 10.1159/000111963  0.523
1988 Inouye H, Kirschner DA. Membrane interactions in nerve myelin: II. Determination of surface charge from biochemical data. Biophysical Journal. 53: 247-60. PMID 3345333 DOI: 10.1016/S0006-3495(88)83086-8  0.433
1988 Inouye H, Kirschner DA. Membrane interactions in nerve myelin. I. Determination of surface charge from effects of pH and ionic strength on period. Biophysical Journal. 53: 235-45. PMID 3345332 DOI: 10.1016/S0006-3495(88)83085-6  0.387
1988 Karthigasan J, Kirschner DA. Membrane interactions are altered in myelin isolated from central and peripheral nervous system tissues. Journal of Neurochemistry. 51: 228-36. PMID 3132532 DOI: 10.1111/J.1471-4159.1988.Tb04860.X  0.547
1988 Ganser AL, Kerner A, Brown B, Davisson MT, Kirschner DA. A Survey of Neurological Mutant Mice. pp 110–122 Developmental Neuroscience. 10: 110-122. DOI: 10.1159/000111962  0.457
1987 Kirschner DA, Inouye H, Duffy LK, Sinclair A, Lind M, Selkoe DJ. Synthetic peptide homologous to beta protein from Alzheimer disease forms amyloid-like fibrils in vitro. Proceedings of the National Academy of Sciences of the United States of America. 84: 6953-7. PMID 3477820 DOI: 10.1073/Pnas.84.19.6953  0.312
1987 Billings-Gagliardi S, Kerner AL, Kirschner DA, Wolf MK. Shiverer jimpy double mutant mice. III. Comparison of shimld*jpmsd and shi*jp phenotypes demonstrates dissimilar interactions of allelic mutations. Brain Research. 388: 199-214. PMID 2445411 DOI: 10.1016/0169-328X(87)90027-1  0.373
1986 Billings-Gagliardi S, Wolf MK, Kirschner DA, Kerner AL. Shiverer jimpy double mutant mice. II. Morphological evidence supports reciprocal intergenic suppression. Brain Research. 374: 54-62. PMID 3719330 DOI: 10.1016/0006-8993(86)90394-X  0.42
1986 Kirschner DA, Abraham C, Selkoe DJ. X-ray diffraction from intraneuronal paired helical filaments and extraneuronal amyloid fibers in Alzheimer disease indicates cross-beta conformation. Proceedings of the National Academy of Sciences of the United States of America. 83: 503-7. PMID 3455785 DOI: 10.1073/Pnas.83.2.503  0.338
1985 Inouye H, Ganser AL, Kirschner DA. Shiverer and normal peripheral myelin compared: basic protein localization, membrane interactions, and lipid composition. Journal of Neurochemistry. 45: 1911-22. PMID 4056798 DOI: 10.1111/J.1471-4159.1985.Tb10551.X  0.548
1985 Ganser AL, Kirschner DA. The interaction of mercurials with myelin: comparison of in vitro and in vivo effects. Neurotoxicology. 6: 63-77. PMID 3873038  0.329
1984 Inouye H, Kirschner DA. New X-ray spacings from central myelinated tissue. Journal of Neurocytology. 13: 883-94. PMID 6534975 DOI: 10.1007/Bf01148591  0.481
1984 Ganser AL, Kirschner DA. Differential expression of gangliosides on the surfaces of myelinated nerve fibers. Journal of Neuroscience Research. 12: 245-55. PMID 6502752 DOI: 10.1002/Jnr.490120212  0.36
1984 Inouye H, Kirschner DA. Effects of ZnCl2 on membrane interactions in myelin of normal and shiverer mice. Biochimica Et Biophysica Acta. 776: 197-208. PMID 6206893 DOI: 10.1016/0005-2736(84)90209-8  0.588
1983 Brown FR, Chen WW, Kirschner DA, Frayer KL, Powers JM, Moser AB, Moser HW. Myelin membrane from adrenoleukodystrophy brain white matter--biochemical properties. Journal of Neurochemistry. 41: 341-8. PMID 6875541 DOI: 10.1111/J.1471-4159.1983.Tb04748.X  0.423
1983 Ganser AL, Kirschner DA, Willinger M. Ganglioside localization on myelinated nerve fibres by cholera toxin binding. Journal of Neurocytology. 12: 921-38. PMID 6363631 DOI: 10.1007/Bf01153342  0.399
1982 Kirschner DA, Sapirstein VS. Triethyl tin-induced myelin oedema: an intermediate swelling state detected by X-ray diffraction. Journal of Neurocytology. 11: 559-69. PMID 6215467 DOI: 10.1007/Bf01262424  0.463
1982 Kirschner DA, Ganser AL. Myelin labeled with mercuric chloride. Asymmetric localization of phosphatidylethanolamine plasmalogen. Journal of Molecular Biology. 157: 635-58. PMID 6214639 DOI: 10.1016/0022-2836(82)90503-4  0.474
1981 Hollingshead CJ, Caspar DL, Melchior V, Kirschner DA. Compaction and particle segregation in myelin membrane arrays. The Journal of Cell Biology. 89: 631-44. PMID 7251668  0.569
1981 Kirschner DA, Hollingshead CJ. Processing for electron microscopy alters membrane structure and packing in myelin. Journal of Ultrastructure Research. 73: 211-32. PMID 6163867 DOI: 10.1016/S0022-5320(80)90125-2  0.332
1980 Caspar DL, Melchior V, Hollingshead CJ, Kirschner DA. Dynamics of myelin membrane contacts. Society of General Physiologists Series. 34: 195-211. PMID 7384835  0.626
1980 Kirschner DA, Ganser AL. Compact myelin exists in the absence of basic protein in the shiverer mutant mouse. Nature. 283: 207-10. PMID 6153124 DOI: 10.1038/283207A0  0.592
1979 Kirschner DA, Hollingshead CJ, Thaxton C, Caspar DL, Goodenough DA. Structural states of myelin observed by x-ray diffraction and freeze-fracture electron microscopy. The Journal of Cell Biology. 82: 140-9. PMID 479295 DOI: 10.1083/Jcb.82.1.140  0.647
1979 Padrón R, Mateu L, Kirschner DA. X-ray diffraction study of the kinetics of myelin lattice swelling. Effect of divalent cations. Biophysical Journal. 28: 231-9. PMID 122265 DOI: 10.1016/S0006-3495(79)85173-5  0.697
1976 Kirschner DA, Caspar DL, Schoenborn BP, Nunes AC. Neutron diffraction studies of nerve myelin. Brookhaven Symposia in Biology. III68-III76. PMID 986860  0.657
1976 Kirschner DA, Sidman RL. X-ray diffraction study of myelin structure in immature and mutant mice. Biochimica Et Biophysica Acta. 448: 73-87. PMID 971429 DOI: 10.1016/0005-2736(76)90077-8  0.668
1976 Hedley-Whyte ET, Kirschner DA. Morphological evidence of alteration in myelinstructure with maturation. Brain Research. 113: 487-97. PMID 953750 DOI: 10.1016/0006-8993(76)90051-2  0.42
1975 Kirschner DA, Caspar DL. Myelin structure transformed by dimethylsulfoxide. Proceedings of the National Academy of Sciences of the United States of America. 72: 3513-7. PMID 1059139 DOI: 10.1073/Pnas.72.9.3513  0.676
1972 Kirschner DA, Caspar DLD. COMPARATIVE DIFFRACTION STUDIES ON MYELIN MEMBRANES. Annals of the New York Academy of Sciences. 195: 309-320. PMID 29090786 DOI: 10.1111/J.1749-6632.1972.Tb54811.X  0.502
1972 Kirschner DA, Caspar DL. Comparative diffraction studies on myelin membranes. Annals of the New York Academy of Sciences. 195: 309-20. PMID 4504094  0.645
1971 Caspar DL, Kirschner DA. Myelin membrane structure at 10 A resolution. Nature: New Biology. 231: 46-52. PMID 5283387 DOI: 10.1038/Newbio231046A0  0.656
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