Aurnab Ghose - Publications

IISER Pune, Pune, Maharashtra, India 
Development and organisation of neural circuits

41 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Ghate K, Mutalik SP, Kavitha Sthanam L, Sen S, Ghose A. Fmn2 regulates growth cone motility by mediating a molecular clutch to generate traction forces. Neuroscience. PMID 33002558 DOI: 10.1016/j.neuroscience.2020.09.046  1
2017 Rale A, Shendye N, Bodas DS, Subhedar N, Ghose A. CART neuropeptide modulates the extended amygdalar CeA-vBNST circuit to gate expression of innate fear. Psychoneuroendocrinology. 85: 69-77. PMID 28825977 DOI: 10.1016/j.psyneuen.2017.08.012  1
2015 Sahasrabudhe A, Ghate K, Mutalik S, Jacob A, Ghose A. Formin-2 regulates stabilization of filopodial tip adhesions in growth cones and affects neuronal outgrowth and pathfinding in vivo. Development (Cambridge, England). PMID 26718007 DOI: 10.1242/dev.130104  1
2014 Sharma A, Rale A, Utturwar K, Ghose A, Subhedar N. Identification of the CART neuropeptide circuitry processing TMT-induced predator stress. Psychoneuroendocrinology. 50: 194-208. PMID 25233338 DOI: 10.1016/j.psyneuen.2014.08.019  1
2014 Akash G, Kaniganti T, Tiwari NK, Subhedar NK, Ghose A. Differential distribution and energy status-dependent regulation of the four CART neuropeptide genes in the zebrafish brain. The Journal of Comparative Neurology. 522: 2266-85. PMID 24374761 DOI: 10.1002/cne.23532  1
2014 Saha S, Dasgupta R, Ghose A, Mullick K, Dey KN. A comparative study of tag SNP selection using clustering Lecture Notes in Computer Science (Including Subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics). 8321: 209-222.  0.4
2013 Chatterjee S, Ghose A, Sharma A, Guha G, Mukherjee D, Frankel R. Comparing newer oral anti-platelets prasugrel and ticagrelor in reduction of ischemic events-evidence from a network meta-analysis. Journal of Thrombosis and Thrombolysis. 36: 223-32. PMID 23212803 DOI: 10.1007/s11239-012-0838-z  1
2013 Sahasrabudhe A, Vittal V, Ghose A. Peeping in on the cytoskeleton: Light microscopy approaches to actin and microtubule organization Current Science. 105: 1562-1570.  1
2012 Gingrich DE, Lisko JG, Curry MA, Cheng M, Quail M, Lu L, Wan W, Albom MS, Angeles TS, Aimone LD, Haltiwanger RC, Wells-Knecht K, Ott GR, Ghose AK, Ator MA, et al. Discovery of an orally efficacious inhibitor of anaplastic lymphoma kinase. Journal of Medicinal Chemistry. 55: 4580-93. PMID 22564207 DOI: 10.1021/jm201550q  1
2012 Ghose AK, Herbertz T, Hudkins RL, Dorsey BD, Mallamo JP. Knowledge-Based, Central Nervous System (CNS) Lead Selection and Lead Optimization for CNS Drug Discovery. Acs Chemical Neuroscience. 3: 50-68. PMID 22267984 DOI: 10.1021/cn200100h  1
2012 Breslin HJ, Lane BM, Ott GR, Ghose AK, Angeles TS, Albom MS, Cheng M, Wan W, Haltiwanger RC, Wells-Knecht KJ, Dorsey BD. Design, synthesis, and anaplastic lymphoma kinase (ALK) inhibitory activity for a novel series of 2,4,8,22-tetraazatetracyclo[³,⁷.1⁹,¹³]docosa-1(20),3(22),4,6,9(21),10,12,16,18-nonaene macrocycles. Journal of Medicinal Chemistry. 55: 449-64. PMID 22172029 DOI: 10.1021/jm201333e  1
2012 Rowbottom MW, Faraoni R, Chao Q, Campbell BT, Lai AG, Setti E, Ezawa M, Sprankle KG, Abraham S, Tran L, Struss B, Gibney M, Armstrong RC, Gunawardane RN, Nepomuceno RR, ... ... Ghose AK, et al. Identification of 1-(3-(6,7-dimethoxyquinazolin-4-yloxy)phenyl)-3-(5-(1,1,1-trifluoro-2-methylpropan-2-yl)isoxazol-3-yl)urea hydrochloride (CEP-32496), a highly potent and orally efficacious inhibitor of V-RAF murine sarcoma viral oncogene homologue B1 (BRAF) V600E. Journal of Medicinal Chemistry. 55: 1082-105. PMID 22168626 DOI: 10.1021/jm2009925  1
2012 Mukherjee A, Subhedar NK, Ghose A. Ontogeny of the cocaine- and amphetamine-regulated transcript (CART) neuropeptide system in the brain of zebrafish, Danio rerio. The Journal of Comparative Neurology. 520: 770-97. PMID 22009187 DOI: 10.1002/cne.22779  1
2012 Learn KS, Wagner JC, Albom MS, Angeles TS, Huang Z, Ghose AK, Wan W, Cheng M, Dorsey BD, Ott GR. Design of 7-amino-6-chloro-3H-imidazo[4,5-b]pyridine scaffold from 5-chloro-2,4-diaminopyrimidine pharmacophore: Identification of potent inhibitors of anaplastic lymphoma kinase Medchemcomm. 3: 1138-1142. DOI: 10.1039/c2md20061a  1
2012 Sahasrabudhe A, Ghose A. Cytoskeletal remodeling in the establishment of the neuronal circuitry Journal of the Indian Institute of Science. 92: 403-410.  1
2011 Tripathy R, McHugh RJ, Ghose AK, Ott GR, Angeles TS, Albom MS, Huang Z, Aimone LD, Cheng M, Dorsey BD. Pyrazolone-based anaplastic lymphoma kinase (ALK) inhibitors: control of selectivity by a benzyloxy group. Bioorganic & Medicinal Chemistry Letters. 21: 7261-4. PMID 22061645 DOI: 10.1016/j.bmcl.2011.10.055  1
2011 Ghose A, Shashidhara LS. Cyclin beyond the cell cycle: new partners at the synapse. Developmental Cell. 21: 601-2. PMID 22014516 DOI: 10.1016/j.devcel.2011.09.015  1
2011 Ott GR, Wells GJ, Thieu TV, Quail MR, Lisko JG, Mesaros EF, Gingrich DE, Ghose AK, Wan W, Lu L, Cheng M, Albom MS, Angeles TS, Huang Z, Aimone LD, et al. 2,7-disubstituted-pyrrolo[2,1-f][1,2,4]triazines: new variant of an old template and application to the discovery of anaplastic lymphoma kinase (ALK) inhibitors with in vivo antitumor activity. Journal of Medicinal Chemistry. 54: 6328-41. PMID 21859094 DOI: 10.1021/jm200758k  1
2010 Milkiewicz KL, Weinberg LR, Albom MS, Angeles TS, Cheng M, Ghose AK, Roemmele RC, Theroff JP, Underiner TL, Zificsak CA, Dorsey BD. Synthesis and structure-activity relationships of 1,2,3,4-tetrahydropyrido[2,3-b]pyrazines as potent and selective inhibitors of the anaplastic lymphoma kinase. Bioorganic & Medicinal Chemistry. 18: 4351-62. PMID 20483621 DOI: 10.1016/j.bmc.2010.04.087  1
2010 Ghose A, Van Vactor D. Regulating receptor PTP activity Handbook of Cell Signaling, 2/E. 2: 737-742. DOI: 10.1016/B978-0-12-374145-5.00094-2  1
2009 Prakash S, McLendon HM, Dubreuil CI, Ghose A, Hwa J, Dennehy KA, Tomalty KM, Clark KL, Van Vactor D, Clandinin TR. Complex interactions amongst N-cadherin, DLAR, and Liprin-alpha regulate Drosophila photoreceptor axon targeting. Developmental Biology. 336: 10-9. PMID 19766621 DOI: 10.1016/j.ydbio.2009.09.016  1
2009 Lu L, Ghose AK, Quail MR, Albom MS, Durkin JT, Holskin BP, Angeles TS, Meyer SL, Ruggeri BA, Cheng M. ALK mutants in the kinase domain exhibit altered kinase activity and differential sensitivity to small molecule ALK inhibitors. Biochemistry. 48: 3600-9. PMID 19249873 DOI: 10.1021/bi8020923  1
2008 Tsai PI, Kao HH, Grabbe C, Lee YT, Ghose A, Lai TT, Peng KP, Van Vactor D, Palmer RH, Chen RH, Yeh SR, Chien CT. Fak56 functions downstream of integrin alphaPS3betanu and suppresses MAPK activation in neuromuscular junction growth. Neural Development. 3: 26. PMID 18925939 DOI: 10.1186/1749-8104-3-26  1
2008 Ghose AK, Herbertz T, Pippin DA, Salvino JM, Mallamo JP. Knowledge based prediction of ligand binding modes and rational inhibitor design for kinase drug discovery. Journal of Medicinal Chemistry. 51: 5149-71. PMID 18710211 DOI: 10.1021/jm800475y  1
2007 Tripathy R, Ghose A, Singh J, Bacon ER, Angeles TS, Yang SX, Albom MS, Aimone LD, Herman JL, Mallamo JP. 1,2,3-Thiadiazole substituted pyrazolones as potent KDR/VEGFR-2 kinase inhibitors. Bioorganic & Medicinal Chemistry Letters. 17: 1793-8. PMID 17239587 DOI: 10.1016/j.bmcl.2006.12.054  1
2006 Johnson KG, Tenney AP, Ghose A, Duckworth AM, Higashi ME, Parfitt K, Marcu O, Heslip TR, Marsh JL, Schwarz TL, Flanagan JG, Van Vactor D. The HSPGs Syndecan and Dallylike bind the receptor phosphatase LAR and exert distinct effects on synaptic development. Neuron. 49: 517-31. PMID 16476662 DOI: 10.1016/j.neuron.2006.01.026  1
2004 Johnson KG, Ghose A, Epstein E, Lincecum J, O'Connor MB, Van Vactor D. Axonal heparan sulfate proteoglycans regulate the distribution and efficiency of the repellent slit during midline axon guidance. Current Biology : Cb. 14: 499-504. PMID 15043815 DOI: 10.1016/j.cub.2004.02.005  1
2002 Ghose A, Van Vactor D. GAPs in Slit-Robo signaling. Bioessays : News and Reviews in Molecular, Cellular and Developmental Biology. 24: 401-4. PMID 12001262 DOI: 10.1002/bies.10080  1
2001 Fleming J, Ghose A, Harrison PR. Molecular mechanisms of cancer prevention by selenium compounds. Nutrition and Cancer. 40: 42-9. PMID 11799922 DOI: 10.1207/S15327914NC401_9  1
2001 Ghose A, Fleming J, El-Bayoumy K, Harrison PR. Enhanced sensitivity of human oral carcinomas to induction of apoptosis by selenium compounds: involvement of mitogen-activated protein kinase and Fas pathways. Cancer Research. 61: 7479-87. PMID 11606383  1
2001 Ghose A, Fleming J, Harrison PR. Selenium and signal transduction: roads to cell death and anti-tumour activity. Biofactors (Oxford, England). 14: 127-33. PMID 11568449  1
1995 Gowravaram MR, Tomczuk BE, Johnson JS, Delecki D, Cook ER, Ghose AK, Mathiowetz AM, Spurlino JC, Rubin B, Smith DL. Inhibition of matrix metalloproteinases by hydroxamates containing heteroatom-based modifications of the P1' group. Journal of Medicinal Chemistry. 38: 2570-81. PMID 7629797 DOI: 10.1021/jm00014a010  1
1991 Viswanadhan VN, Ghose AK, Hanna NB, Matsumoto SS, Avery TL, Revankar GR, Robins RK. Analysis of the in vitro antitumor activity of novel purine-6-sulfenamide, -sulfinamide, and -sulfonamide nucleosides and certain related compounds using a computer-aided receptor modeling procedure. Journal of Medicinal Chemistry. 34: 526-32. PMID 1995873  1
1990 Ghose AK, Crippen GM. Modeling the benzodiazepine receptor binding site by the general three-dimensional structure-directed quantitative structure-activity relationship method REMOTEDISC. Molecular Pharmacology. 37: 725-34. PMID 2160062  1
1989 Ghose AK, Viswanadhan VN, Sanghvi YS, Nord LD, Willis RC, Revankar GR, Robins RK. Structural mimicry of adenosine by the antitumor agents 4-methoxy- and 4-amino-8-(beta-D-ribofuranosylamino)pyrimido[5,4-d]pyrimidine as viewed by a molecular modeling method. Proceedings of the National Academy of Sciences of the United States of America. 86: 8242-6. PMID 2813389  1
1989 Ghose AK, Crippen GM, Revankar GR, McKernan PA, Smee DF, Robins RK. Analysis of the in vitro antiviral activity of certain ribonucleosides against parainfluenza virus using a novel computer aided receptor modeling procedure. Journal of Medicinal Chemistry. 32: 746-56. PMID 2539476  1
1987 Ghose AK, Crippen GM. Atomic physicochemical parameters for three-dimensional-structure-directed quantitative structure-activity relationships. 2. Modeling dispersive and hydrophobic interactions. Journal of Chemical Information and Computer Sciences. 27: 21-35. PMID 3558506  1
1985 Ghose AK, Crippen GM. Use of physicochemical parameters in distance geometry and related three-dimensional quantitative structure-activity relationships: a demonstration using Escherichia coli dihydrofolate reductase inhibitors. Journal of Medicinal Chemistry. 28: 333-46. PMID 3882967  1
1984 Ghose AK, Crippen GM. General distance geometry three-dimensional receptor model for diverse dihydrofolate reductase inhibitors. Journal of Medicinal Chemistry. 27: 901-14. PMID 6737433  1
1983 Ghose AK, Crippen GM. Combined distance geometry analysis of dihydrofolate reductase inhibition by quinazolines and triazines. Journal of Medicinal Chemistry. 26: 996-1010. PMID 6864738  1
1982 Ghose AK, Crippen GM. Quantitative structure-activity relationship by distance geometry: quinazolines as dihydrofolate reductase inhibitors. Journal of Medicinal Chemistry. 25: 892-9. PMID 7120278  1
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