Paulianda J. Jones, Ph.D. - Publications
Affiliations: | 2007 | University of Virginia, Charlottesville, VA |
Year | Citation | Score | |||
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2009 | Brown ML, Eidam HA, Paige M, Jones PJ, Patel MK. Comparative molecular field analysis and synthetic validation of a hydroxyamide-propofol binding and functional block of neuronal voltage-dependent sodium channels. Bioorganic & Medicinal Chemistry. 17: 7056-63. PMID 19747831 DOI: 10.1016/J.Bmc.2008.11.069 | 0.65 | |||
2009 | Wang Y, Jones PJ, Batts TW, Landry V, Patel MK, Brown ML. Ligand-based design and synthesis of novel sodium channel blockers from a combined phenytoin-lidocaine pharmacophore. Bioorganic & Medicinal Chemistry. 17: 7064-72. PMID 19346132 DOI: 10.1016/J.Bmc.2008.10.031 | 0.627 | |||
2009 | Jones PJ, Merrick EC, Batts TW, Hargus NJ, Wang Y, Stables JP, Bertram EH, Brown ML, Patel MK. Modulation of sodium channel inactivation gating by a novel lactam: implications for seizure suppression in chronic limbic epilepsy. The Journal of Pharmacology and Experimental Therapeutics. 328: 201-12. PMID 18952887 DOI: 10.1124/Jpet.108.144709 | 0.649 | |||
2007 | Lenkowski PW, Batts TW, Smith MD, Ko SH, Jones PJ, Taylor CH, McCusker AK, Davis GC, Hartmann HA, White HS, Brown ML, Patel MK. A pharmacophore derived phenytoin analogue with increased affinity for slow inactivated sodium channels exhibits a desired anticonvulsant profile. Neuropharmacology. 52: 1044-54. PMID 17174360 DOI: 10.1016/J.Neuropharm.2006.11.001 | 0.546 | |||
2007 | Jones PJ, Wang Y, Smith MD, Hargus NJ, Eidam HS, White HS, Kapur J, Brown ML, Patel MK. Hydroxyamide analogs of propofol exhibit state-dependent block of sodium channels in hippocampal neurons: implications for anticonvulsant activity. The Journal of Pharmacology and Experimental Therapeutics. 320: 828-36. PMID 17090703 DOI: 10.1124/Jpet.106.111542 | 0.599 | |||
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