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Timothy A. Vortherms, Ph.D. - Publications

Affiliations: 
2004 Purdue University, West Lafayette, IN, United States 
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9 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2009 Strakhova MI, Cuff CA, Manelli AM, Carr TL, Witte DG, Baranowski JL, Vortherms TA, Miller TR, Rundell L, McPherson MJ, Adair RM, Brito AA, Bettencourt BM, Yao BB, Wetter JM, et al. In vitro and in vivo characterization of A-940894: a potent histamine H4 receptor antagonist with anti-inflammatory properties. British Journal of Pharmacology. 157: 44-54. PMID 19413570 DOI: 10.1111/j.1476-5381.2009.00236.x  0.378
2008 Nersesian DL, Black LA, Miller TR, Vortherms TA, Esbenshade TA, Hancock AA, Cowart MD. In vitro SAR of pyrrolidine-containing histamine H3 receptor antagonists: trends across multiple chemical series. Bioorganic & Medicinal Chemistry Letters. 18: 355-9. PMID 18077160 DOI: 10.1016/j.bmcl.2007.10.067  0.333
2007 Vortherms TA, Mosier PD, Westkaemper RB, Roth BL. Differential helical orientations among related G protein-coupled receptors provide a novel mechanism for selectivity. Studies with salvinorin A and the kappa-opioid receptor. The Journal of Biological Chemistry. 282: 3146-56. PMID 17121830 DOI: 10.1074/Jbc.M609264200  0.32
2006 Vortherms TA, Nguyen CH, Bastepe M, Jüppner H, Watts VJ. D2 dopamine receptor-induced sensitization of adenylyl cyclase type 1 is G alpha(s) independent. Neuropharmacology. 50: 576-84. PMID 16376953 DOI: 10.1016/J.Neuropharm.2005.11.004  0.735
2005 Yan F, Mosier PD, Westkaemper RB, Stewart J, Zjawiony JK, Vortherms TA, Sheffler DJ, Roth BL. Identification of the molecular mechanisms by which the diterpenoid salvinorin A binds to kappa-opioid receptors. Biochemistry. 44: 8643-51. PMID 15952771 DOI: 10.1021/Bi050490D  0.357
2005 Goldberg MS, Pisani A, Haburcak M, Vortherms TA, Kitada T, Costa C, Tong Y, Martella G, Tscherter A, Martins A, Bernardi G, Roth BL, Pothos EN, Calabresi P, Shen J. Nigrostriatal dopaminergic deficits and hypokinesia caused by inactivation of the familial Parkinsonism-linked gene DJ-1. Neuron. 45: 489-96. PMID 15721235 DOI: 10.1016/J.Neuron.2005.01.041  0.486
2004 Vortherms TA, Nguyen CH, Berlot CH, Watts VJ. Using molecular tools to dissect the role of Galphas in sensitization of AC1. Molecular Pharmacology. 66: 1617-24. PMID 15361543 DOI: 10.1124/Mol.104.000166  0.7
2004 Vortherms TA, Watts VJ. Sensitization of neuronal A2A adenosine receptors after persistent D2 dopamine receptor activation. The Journal of Pharmacology and Experimental Therapeutics. 308: 221-7. PMID 14566008 DOI: 10.1124/Jpet.103.057083  0.774
2001 Johnston CA, Cumbay MG, Vortherms TA, Watts VJ. Adrenergic agonists induce heterologous sensitization of adenylate cyclase in NS20Y-D(2L) cells. Febs Letters. 497: 85-9. PMID 11377418 DOI: 10.1016/S0014-5793(01)02442-5  0.519
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