| Year |
Citation |
Score |
| 2023 |
An L, Said M, Tran L, Majumder S, Goreshnik I, Lee GR, Juergens D, Dauparas J, Anishchenko I, Coventry B, Bera AK, Kang A, Levine PM, Alvarez V, Pillai A, et al. De novo design of diverse small molecule binders and sensors using Shape Complementary Pseudocycles. Biorxiv : the Preprint Server For Biology. PMID 38187589 DOI: 10.1101/2023.12.20.572602 |
0.345 |
|
| 2023 |
Lee GR, Pellock SJ, Norn C, Tischer D, Dauparas J, Anischenko I, Mercer JAM, Kang A, Bera A, Nguyen H, Goreshnik I, Vafeados D, Roullier N, Han HL, Coventry B, et al. Small-molecule binding and sensing with a designed protein family. Biorxiv : the Preprint Server For Biology. PMID 37961294 DOI: 10.1101/2023.11.01.565201 |
0.409 |
|
| 2023 |
Huang B, Abedi M, Ahn G, Coventry B, Sappington I, Wang R, Schlichthaerle T, Zhang JZ, Wang Y, Goreshnik I, Chiu CW, Chazin-Gray A, Chan S, Gerben S, Murray A, et al. Designed Endocytosis-Triggering Proteins mediate Targeted Degradation. Biorxiv : the Preprint Server For Biology. PMID 37781607 DOI: 10.1101/2023.08.19.553321 |
0.372 |
|
| 2023 |
Bennett NR, Coventry B, Goreshnik I, Huang B, Allen A, Vafeados D, Peng YP, Dauparas J, Baek M, Stewart L, DiMaio F, De Munck S, Savvides SN, Baker D. Improving de novo protein binder design with deep learning. Nature Communications. 14: 2625. PMID 37149653 DOI: 10.1038/s41467-023-38328-5 |
0.313 |
|
| 2023 |
Wu K, Bai H, Chang YT, Redler R, McNally KE, Sheffler W, Brunette TJ, Hicks DR, Morgan TE, Stevens TJ, Broerman A, Goreshnik I, DeWitt M, Chow CM, Shen Y, et al. De novo design of modular peptide-binding proteins by superhelical matching. Nature. PMID 37020023 DOI: 10.1038/s41586-023-05909-9 |
0.344 |
|
| 2022 |
Hunt AC, Case JB, Park YJ, Cao L, Wu K, Walls AC, Liu Z, Bowen JE, Yeh HW, Saini S, Helms L, Zhao YT, Hsiang TY, Starr TN, Goreshnik I, et al. Multivalent designed proteins neutralize SARS-CoV-2 variants of concern and confer protection against infection in mice. Science Translational Medicine. eabn1252. PMID 35412328 DOI: 10.1126/scitranslmed.abn1252 |
0.315 |
|
| 2022 |
Cao L, Coventry B, Goreshnik I, Huang B, Park JS, Jude KM, Marković I, Kadam RU, Verschueren KHG, Verstraete K, Walsh STR, Bennett N, Phal A, Yang A, Kozodoy L, et al. Design of protein binding proteins from target structure alone. Nature. PMID 35332283 DOI: 10.1038/s41586-022-04654-9 |
0.4 |
|
| 2021 |
Hunt AC, Case JB, Park YJ, Cao L, Wu K, Walls AC, Liu Z, Bowen JE, Yeh HW, Saini S, Helms L, Zhao YT, Hsiang TY, Starr TN, Goreshnik I, et al. Multivalent designed proteins protect against SARS-CoV-2 variants of concern. Biorxiv : the Preprint Server For Biology. PMID 34268509 DOI: 10.1101/2021.07.07.451375 |
0.33 |
|
| 2021 |
Sahtoe DD, Coscia A, Mustafaoglu N, Miller LM, Olal D, Vulovic I, Yu TY, Goreshnik I, Lin YR, Clark L, Busch F, Stewart L, Wysocki VH, Ingber DE, Abraham J, et al. Transferrin receptor targeting by de novo sheet extension. Proceedings of the National Academy of Sciences of the United States of America. 118. PMID 33879614 DOI: 10.1073/pnas.2021569118 |
0.306 |
|
| 2020 |
Cao L, Goreshnik I, Coventry B, Case JB, Miller L, Kozodoy L, Chen RE, Carter L, Walls AC, Park YJ, Strauch EM, Stewart L, Diamond MS, Veesler D, Baker D. De novo design of picomolar SARS-CoV-2 miniprotein inhibitors. Science (New York, N.Y.). PMID 32907861 DOI: 10.1126/Science.Abd9909 |
0.402 |
|
| 2020 |
Basanta B, Bick MJ, Bera AK, Norn C, Chow CM, Carter LP, Goreshnik I, Dimaio F, Baker D. An enumerative algorithm for de novo design of proteins with diverse pocket structures. Proceedings of the National Academy of Sciences of the United States of America. PMID 32839327 DOI: 10.1073/Pnas.2005412117 |
0.447 |
|
| 2020 |
Cao L, Goreshnik I, Coventry B, Case JB, Miller L, Kozodoy L, Chen RE, Carter L, Walls L, Park YJ, Stewart L, Diamond M, Veesler D, Baker D. De novo design of picomolar SARS-CoV-2 miniprotein inhibitors. Biorxiv : the Preprint Server For Biology. PMID 32793905 DOI: 10.1101/2020.08.03.234914 |
0.387 |
|
| 2019 |
Dou J, Goreshnik I, Bryan C, Baker D, Strauch EM. Parallelized identification of on- and off-target protein interactions. Molecular Systems Design & Engineering. 5: 349-357. PMID 35265342 DOI: 10.1039/c9me00118b |
0.442 |
|
| 2017 |
Chevalier A, Silva DA, Rocklin GJ, Hicks DR, Vergara R, Murapa P, Bernard SM, Zhang L, Lam KH, Yao G, Bahl CD, Miyashita SI, Goreshnik I, Fuller JT, Koday MT, et al. Massively parallel de novo protein design for targeted therapeutics. Nature. PMID 28953867 DOI: 10.1038/Nature23912 |
0.453 |
|
| 2017 |
Rocklin GJ, Chidyausiku TM, Goreshnik I, Ford A, Houliston S, Lemak A, Carter L, Ravichandran R, Mulligan VK, Chevalier A, Arrowsmith CH, Baker D. Global analysis of protein folding using massively parallel design, synthesis, and testing. Science (New York, N.Y.). 357: 168-175. PMID 28706065 DOI: 10.1126/Science.Aan0693 |
0.43 |
|
| 2017 |
Rocklin GJ, Chidyausiku T, Goreshnik I, Ford A, Houliston S, Arrowsmith C, Baker D. High-Throughput Protein Design Reveals Quantitative Protein Stability Requirements Biophysical Journal. 112: 194a. DOI: 10.1016/J.Bpj.2016.11.1076 |
0.437 |
|
| 2016 |
Rose JC, Huang PS, Camp ND, Ye J, Leidal AM, Goreshnik I, Trevillian BM, Dickinson MS, Cunningham-Bryant D, Debnath J, Baker D, Wolf-Yadlin A, Maly DJ. A computationally engineered RAS rheostat reveals RAS-ERK signaling dynamics. Nature Chemical Biology. PMID 27870838 DOI: 10.1038/Nchembio.2244 |
0.474 |
|
| 2011 |
Goreshnik I, Brock AM, Maly DJ. Biochemical and pharmacological profiling of the pro-survival protein Bcl-xL. Bioorganic & Medicinal Chemistry Letters. 21: 4951-5. PMID 21807512 DOI: 10.1016/J.Bmcl.2011.06.134 |
0.513 |
|
| 2010 |
Goreshnik I, Maly DJ. A small molecule-regulated guanine nucleotide exchange factor. Journal of the American Chemical Society. 132: 938-40. PMID 20020680 DOI: 10.1021/Ja907886V |
0.523 |
|
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