Allan I. Levey - Publications

Affiliations: 
Emory University, Atlanta, GA 

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Year Citation  Score
2024 Wojtas AM, Dammer EB, Guo Q, Ping L, Shantaraman A, Duong DM, Yin L, Fox EJ, Seifar F, Lee EB, Johnson ECB, Lah JJ, Levey AI, Levites Y, Rangaraju S, et al. Proteomic Changes in the Human Cerebrovasculature in Alzheimer's Disease and Related Tauopathies Linked to Peripheral Biomarkers in Plasma and Cerebrospinal Fluid. Medrxiv : the Preprint Server For Health Sciences. PMID 38260316 DOI: 10.1101/2024.01.10.24301099  0.667
2023 Johnson ECB, Bian S, Haque RU, Carter EK, Watson CM, Gordon BA, Ping L, Duong DM, Epstein MP, McDade E, Barthélemy NR, Karch CM, Xiong C, Cruchaga C, Perrin RJ, ... ... Levey AI, et al. Cerebrospinal fluid proteomics define the natural history of autosomal dominant Alzheimer's disease. Nature Medicine. PMID 37550416 DOI: 10.1038/s41591-023-02476-4  0.304
2023 Wynne ME, Ogunbona O, Lane AR, Gokhale A, Zlatic SA, Xu C, Wen Z, Duong DM, Rayaprolu S, Ivanova A, Ortlund EA, Dammer EB, Seyfried NT, Roberts BR, Crocker A, ... ... Levey AI, et al. APOE expression and secretion are modulated by mitochondrial dysfunction. Elife. 12. PMID 37171075 DOI: 10.7554/eLife.85779  0.77
2023 Ehrenberg AJ, Kelberman MA, Liu KY, Dahl MJ, Weinshenker D, Falgàs N, Dutt S, Mather M, Ludwig M, Betts MJ, Winer JR, Teipel S, Weigand AJ, Eschenko O, Hämmerer D, ... ... Levey AI, et al. Priorities for research on neuromodulatory subcortical systems in Alzheimer's disease: Position paper from the NSS PIA of ISTAART. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 36642985 DOI: 10.1002/alz.12937  0.626
2022 Del Campo M, Peeters CFW, Johnson ECB, Vermunt L, Hok-A-Hin YS, van Nee M, Chen-Plotkin A, Irwin DJ, Hu WT, Lah JJ, Seyfried NT, Dammer EB, Herradon G, Meeter LH, van Swieten J, ... ... Levey AI, et al. CSF proteome profiling across the Alzheimer's disease spectrum reflects the multifactorial nature of the disease and identifies specific biomarker panels. Nature Aging. 2: 1040-1053. PMID 37118088 DOI: 10.1038/s43587-022-00300-1  0.554
2022 Chan AWS, Cho IK, Li CX, Zhang X, Patel S, Rusnak R, Raper J, Bachevalier J, Moran SP, Chi T, Cannon KH, Hunter CE, Martin RC, Xiao H, Yang SH, ... ... Levey AI, et al. Cerebral Aβ deposition in an Aβ-precursor protein-transgenic rhesus monkey. Aging Brain. 2. PMID 36589695 DOI: 10.1016/j.nbas.2022.100044  0.546
2022 Rayaprolu S, Bitarafan S, Santiago JV, Betarbet R, Sunna S, Cheng L, Xiao H, Nelson RS, Kumar P, Bagchi P, Duong DM, Goettemoeller AM, Oláh VJ, Rowan M, Levey AI, et al. Cell type-specific biotin labeling in vivo resolves regional neuronal and astrocyte proteomic differences in mouse brain. Nature Communications. 13: 2927. PMID 35614064 DOI: 10.1038/s41467-022-30623-x  0.782
2021 Levey AI, Qiu D, Zhao L, Hu WT, Duong DM, Higginbotham L, Dammer EB, Seyfried NT, Wingo TS, Hales CM, Gámez Tansey M, Goldstein DS, Abrol A, Calhoun VD, Goldstein FC, et al. A phase II study repurposing atomoxetine for neuroprotection in mild cognitive impairment. Brain : a Journal of Neurology. PMID 34919634 DOI: 10.1093/brain/awab452  0.541
2021 Chen MJ, Ramesha S, Weinstock LD, Gao T, Ping L, Xiao H, Dammer EB, Duong DD, Levey AI, Lah JJ, Seyfried NT, Wood LB, Rangaraju S. Extracellular signal-regulated kinase regulates microglial immune responses in Alzheimer's disease. Journal of Neuroscience Research. PMID 33729626 DOI: 10.1002/jnr.24829  0.651
2021 Ramesha S, Rayaprolu S, Bowen CA, Giver CR, Bitarafan S, Nguyen HM, Gao T, Chen MJ, Nwabueze N, Dammer EB, Engstrom AK, Xiao H, Pennati A, Seyfried NT, Katz DJ, ... ... Levey AI, et al. Unique molecular characteristics and microglial origin of Kv1.3 channel-positive brain myeloid cells in Alzheimer's disease. Proceedings of the National Academy of Sciences of the United States of America. 118. PMID 33649184 DOI: 10.1073/pnas.2013545118  0.787
2020 Rayaprolu S, Higginbotham L, Bagchi P, Watson CM, Zhang T, Levey AI, Rangaraju S, Seyfried NT. Systems-based proteomics to resolve the biology of Alzheimer's disease beyond amyloid and tau. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 32898852 DOI: 10.1038/S41386-020-00840-3  0.809
2020 Beckmann ND, Lin WJ, Wang M, Cohain AT, Charney AW, Wang P, Ma W, Wang YC, Jiang C, Audrain M, Comella PH, Fakira AK, Hariharan SP, Belbin GM, Girdhar K, ... Levey AI, et al. Multiscale causal networks identify VGF as a key regulator of Alzheimer's disease. Nature Communications. 11: 3942. PMID 32770063 DOI: 10.1038/S41467-020-17405-Z  0.398
2020 Wan YW, Al-Ouran R, Mangleburg CG, Perumal TM, Lee TV, Allison K, Swarup V, Funk CC, Gaiteri C, Allen M, Wang M, Neuner SM, Kaczorowski CC, Philip VM, Howell GR, ... ... Levey AI, et al. Meta-Analysis of the Alzheimer's Disease Human Brain Transcriptome and Functional Dissection in Mouse Models. Cell Reports. 32: 107908. PMID 32668255 DOI: 10.1016/J.Celrep.2020.107908  0.412
2020 Yu L, Tasaki S, Schneider JA, Arfanakis K, Duong DM, Wingo AP, Wingo TS, Kearns N, Thatcher GRJ, Seyfried NT, Levey AI, De Jager PL, Bennett DA. Cortical Proteins Associated With Cognitive Resilience in Community-Dwelling Older Persons. Jama Psychiatry. PMID 32609320 DOI: 10.1001/Jamapsychiatry.2020.1807  0.311
2020 Swarup V, Chang TS, Duong DM, Dammer EB, Dai J, Lah JJ, Johnson ECB, Seyfried NT, Levey AI, Geschwind DH. Identification of Conserved Proteomic Networks in Neurodegenerative Dementia. Cell Reports. 31: 107807. PMID 32579933 DOI: 10.1016/J.Celrep.2020.107807  0.419
2020 Wingo AP, Fan W, Duong DM, Gerasimov ES, Dammer EB, Liu Y, Harerimana NV, White B, Thambisetty M, Troncoso JC, Kim N, Schneider JA, Hajjar IM, Lah JJ, Bennett DA, ... ... Levey AI, et al. Publisher Correction: Shared proteomic effects of cerebral atherosclerosis and Alzheimer's disease on the human brain. Nature Neuroscience. PMID 32576978 DOI: 10.1038/S41593-020-0662-2  0.34
2020 Schindler SE, Jicha GA, Nelson PT, Keene CD, Blennow K, Molinuevo JL, Masters CL, Hansson O, Teunissen CE, Galasko D, Shaw LM, Levey AI. Maximizing Safety in the Conduct of Alzheimer's Disease Fluid Biomarker Research in the Era of COVID-19. Journal of Alzheimer's Disease : Jad. PMID 32568212 DOI: 10.3233/JAD-200684  0.316
2020 Zhou M, Haque RU, Dammer EB, Duong DM, Ping L, Johnson ECB, Lah JJ, Levey AI, Seyfried NT. Targeted mass spectrometry to quantify brain-derived cerebrospinal fluid biomarkers in Alzheimer's disease. Clinical Proteomics. 17: 19. PMID 32514259 DOI: 10.1186/S12014-020-09285-8  0.413
2020 van Dyck CH, Arnsten AFT, Padala PR, Brawman-Mintzer O, Lerner AJ, Porsteinsson AP, Scherer RW, Levey AI, Herrmann N, Jamil N, Mintzer JE, Lanctôt KL, Rosenberg PB. Neurobiologic Rationale for Treatment of Apathy in Alzheimer's Disease With Methylphenidate. The American Journal of Geriatric Psychiatry : Official Journal of the American Association For Geriatric Psychiatry. PMID 32461027 DOI: 10.1016/J.Jagp.2020.04.026  0.358
2020 Wingo AP, Fan W, Duong DM, Gerasimov ES, Dammer EB, Liu Y, Harerimana NV, White B, Thambisetty M, Troncoso JC, Kim N, Schneider JA, Hajjar IM, Lah JJ, Bennett DA, ... ... Levey AI, et al. Shared proteomic effects of cerebral atherosclerosis and Alzheimer's disease on the human brain. Nature Neuroscience. PMID 32424284 DOI: 10.1038/S41593-020-0635-5  0.34
2020 Rayaprolu S, Gao T, Xiao H, Ramesha S, Weinstock LD, Shah J, Duong DM, Dammer EB, Webster JA, Lah JJ, Wood LB, Betarbet R, Levey AI, Seyfried NT, Rangaraju S. Flow-cytometric microglial sorting coupled with quantitative proteomics identifies moesin as a highly-abundant microglial protein with relevance to Alzheimer's disease. Molecular Neurodegeneration. 15: 28. PMID 32381088 DOI: 10.1186/S13024-020-00377-5  0.777
2020 Haque RU, Pongos AL, Manzaneres CM, Lah JJ, Levey AI, Clifford GD. Deep convolutional neural networks and transfer learning for measuring cognitive impairment using eye-tracking in a distributed tablet-based environment. Ieee Transactions On Bio-Medical Engineering. PMID 32340935 DOI: 10.1109/Tbme.2020.2990734  0.31
2020 Johnson ECB, Dammer EB, Duong DM, Ping L, Zhou M, Yin L, Higginbotham LA, Guajardo A, White B, Troncoso JC, Thambisetty M, Montine TJ, Lee EB, Trojanowski JQ, Beach TG, ... ... Levey AI, et al. Large-scale proteomic analysis of Alzheimer's disease brain and cerebrospinal fluid reveals early changes in energy metabolism associated with microglia and astrocyte activation. Nature Medicine. PMID 32284590 DOI: 10.1038/S41591-020-0815-6  0.694
2019 Haque RU, Levey AI. Alzheimer's disease: A clinical perspective and future nonhuman primate research opportunities. Proceedings of the National Academy of Sciences of the United States of America. PMID 31871211 DOI: 10.1073/pnas.1912954116  0.392
2019 Ayer AH, Wojta K, Ramos EM, Dokuru D, Chen JA, Karydas AM, Papatriantafyllou JD, Agiomyrgiannakis D, Kamtsadeli V, Tsinia N, Sali D, Gylys KH, Agosta F, Filippi M, Small GW, ... ... Levey A, et al. Frequency of the TREM2 R47H Variant in Various Neurodegenerative Disorders. Alzheimer Disease and Associated Disorders. PMID 31513029 DOI: 10.1097/Wad.0000000000000339  0.339
2019 Higginbotham L, Dammer EB, Duong DM, Modeste E, Montine TJ, Lah JJ, Levey AI, Seyfried NT. Network Analysis of a Membrane-Enriched Brain Proteome across Stages of Alzheimer's Disease. Proteomes. 7. PMID 31461916 DOI: 10.3390/Proteomes7030030  0.361
2019 Goetz ME, Hanfelt JJ, John SE, Bergquist SH, Loring DW, Quyyumi A, Clifford GD, Vaccarino V, Goldstein F, Johnson Nd TM, Kuerston R, Marcus M, Levey AI, Lah JJ. Rationale and Design of the Emory Healthy Aging and Emory Healthy Brain Studies. Neuroepidemiology. 1-14. PMID 31454799 DOI: 10.1159/000501856  0.345
2019 Gao T, Jernigan J, Raza SA, Dammer EB, Xiao H, Seyfried NT, Levey AI, Rangaraju S. Transcriptional regulation of homeostatic and disease-associated-microglial genes by IRF1, LXRβ, and CEBPα. Glia. PMID 31301160 DOI: 10.1002/Glia.23678  0.752
2019 Wingo TS, Cutler DJ, Wingo AP, Le NA, Rabinovici GD, Miller BL, Lah JJ, Levey AI. Association of Early-Onset Alzheimer Disease With Elevated Low-density Lipoprotein Cholesterol Levels and Rare Genetic Coding Variants of APOB. Jama Neurology. PMID 31135820 DOI: 10.1001/Jamaneurol.2019.0648  0.349
2019 Nelson PT, Dickson DW, Trojanowski JQ, Jack CR, Boyle PA, Arfanakis K, Rademakers R, Alafuzoff I, Attems J, Brayne C, Coyle-Gilchrist ITS, Chui HC, Fardo DW, Flanagan ME, Halliday G, ... ... Levey AI, et al. Limbic-predominant age-related TDP-43 encephalopathy (LATE): consensus working group report. Brain : a Journal of Neurology. PMID 31039256 DOI: 10.1093/Brain/Awz099  0.36
2019 Levey AI, Lah JJ, Hu WT, Wingo TS, Hales CM, Manzanares C, Tansey MG, Goldstein DS, Zhao L, Galasko DR, Edland SD, Hanfelt J, Weinshenker D. O4-11-05: A PROOF OF CONCEPT PHASE II STUDY REPURPOSING ATOMOXETINE FOR NEUROPROTECTION IN MILD COGNITIVE IMPAIRMENT: EVIDENCE FOR TARGET ENGAGEMENT, REGULATION OF CSF BIOMARKERS, AND DISEASE-MODIFYING POTENTIAL Alzheimer's & Dementia. 15: P1263-P1264. DOI: 10.1016/J.Jalz.2019.06.4804  0.523
2019 Ping L, Higginbotham LA, Dammer EB, Duong D, Zhou M, Wingo TS, Johnson EC, Lah JJ, Levey AI, Seyfried NT. INTEGRATIVE PROTEOMICS LINKS CEREBROSPINAL FLUID BIOMARKERS TO PATHOLOGICAL NETWORKS IN THE ALZHEIMER’S DISEASE BRAIN Alzheimer's & Dementia. 15: P191. DOI: 10.1016/J.Jalz.2019.06.4517  0.302
2019 Guo C, Hsieh Y, Yalamanchili HK, Abreha M, Al-Ouran R, Li Y, Dammer EB, Lah JJ, Levey AI, Bennett DA, Jager PLD, Seyfried NT, Liu Z, Shulman JM. P4-130: Tau-Mediated Disruption Of The Spliceosome Triggers Cryptic Rna Splicing And Neurodegeneration In Alzheimer'S Disease Alzheimers & Dementia. 15. DOI: 10.1016/J.Jalz.2019.06.3791  0.346
2019 Modeste ES, Dammer EB, Duong D, Lah JJ, Levey AI, Wingo AP, Wingo TS, Seyfried NT. P4-115: SEX-SPECIFIC PROTEIN DIFFERENCES LINKED TO ALZHEIMER'S DISEASE RISK UNCOVERED BY A COEXPRESSION-REGRESSION FRAMEWORK Alzheimer's & Dementia. 15: P1320-P1320. DOI: 10.1016/J.Jalz.2019.06.3776  0.354
2019 Lee TV, Allison KS, Ojelade SA, Lah JJ, Levey AI, Seyfried NT, Shulman JM. P3-126: FUNCTIONAL DISSECTION OF AN ALZHEIMER'S DISEASE SUSCEPTIBILITY GENE NETWORK Alzheimer's & Dementia. 15: P978-P979. DOI: 10.1016/J.Jalz.2019.06.3154  0.318
2019 Johnson ECB, Dammer EB, Duong D, Yin L, Thambisetty M, Troncoso JC, Lah JJ, Levey AI, Seyfried NT. P2-218: Deep Proteomic Network Analysis Of Alzheimer'S Disease Brain Reveals Alterations In Rna Binding Proteins And Rna Splicing Associated With Disease Alzheimers & Dementia. 15. DOI: 10.1016/J.Jalz.2019.06.2625  0.329
2019 Weinstock L, Gao T, Raza SA, Xiao H, Ramesha S, Levey AI, Wood L, Rangaraju S. P2-205: Distinct Baseline And Stress-Induced Mapk Signaling Responses Characterize Microglia In Alzheimer'S Disease Models Alzheimers & Dementia. 15. DOI: 10.1016/J.Jalz.2019.06.2612  0.324
2018 Dai J, Johnson ECB, Dammer EB, Duong DM, Gearing M, Lah JJ, Levey AI, Wingo TS, Seyfried NT. Effects of Genotype on Brain Proteomic Network and Cell Type Changes in Alzheimer's Disease. Frontiers in Molecular Neuroscience. 11: 454. PMID 30618606 DOI: 10.3389/Fnmol.2018.00454  0.375
2018 Swarup V, Hinz FI, Rexach JE, Noguchi KI, Toyoshiba H, Oda A, Hirai K, Sarkar A, Seyfried NT, Cheng C, Haggarty SJ, Grossman M, Van Deerlin VM, Trojanowski JQ, ... ... Levey AI, et al. Identification of evolutionarily conserved gene networks mediating neurodegenerative dementia. Nature Medicine. PMID 30510257 DOI: 10.1038/S41591-018-0223-3  0.329
2018 Park K, Lonsberry GE, Gearing M, Levey AI, Desai JP. Viscoelastic Properties of Human Autopsy Brain Tissues as Biomarkers for Alzheimer's Diseases. Ieee Transactions On Bio-Medical Engineering. PMID 30371351 DOI: 10.1109/Tbme.2018.2878555  0.375
2018 Johnson ECB, Dammer EB, Duong DM, Yin L, Thambisetty M, Troncoso JC, Lah JJ, Levey AI, Seyfried NT. Deep proteomic network analysis of Alzheimer's disease brain reveals alterations in RNA binding proteins and RNA splicing associated with disease. Molecular Neurodegeneration. 13: 52. PMID 30286791 DOI: 10.1186/S13024-018-0282-4  0.425
2018 Abreha MH, Dammer EB, Ping L, Zhang T, Duong DM, Gearing M, Lah JJ, Levey AI, Seyfried NT. Quantitative Analysis of the Brain Ubiquitylome in Alzheimer's Disease. Proteomics. e1800108. PMID 30230243 DOI: 10.1002/Pmic.201800108  0.412
2018 Wang M, Beckmann ND, Roussos P, Wang E, Zhou X, Wang Q, Ming C, Neff R, Ma W, Fullard JF, Hauberg ME, Bendl J, Peters MA, Logsdon B, Wang P, ... ... Levey AI, et al. The Mount Sinai cohort of large-scale genomic, transcriptomic and proteomic data in Alzheimer's disease. Scientific Data. 5: 180185. PMID 30204156 DOI: 10.1038/Sdata.2018.185  0.368
2018 Rangaraju S, Dammer EB, Raza SA, Gao T, Xiao H, Betarbet R, Duong DM, Webster JA, Hales CM, Lah JJ, Levey AI, Seyfried NT. Quantitative proteomics of acutely-isolated mouse microglia identifies novel immune Alzheimer's disease-related proteins. Molecular Neurodegeneration. 13: 34. PMID 29954413 DOI: 10.1186/S13024-018-0266-4  0.78
2018 Steenland K, Zhao L, John SE, Goldstein FC, Levey A, Alvaro A. A 'Framingham-like' Algorithm for Predicting 4-Year Risk of Progression to Amnestic Mild Cognitive Impairment or Alzheimer's Disease Using Multidomain Information. Journal of Alzheimer's Disease : Jad. PMID 29843232 DOI: 10.3233/Jad-170769  0.324
2018 Bishof I, Dammer EB, Duong DM, Kundinger S, Gearing M, Lah JJ, Levey AI, Seyfried NT. RNA-binding proteins with basic-acidic dipeptide (BAD) domains self-assemble and aggregate in Alzheimer's disease. The Journal of Biological Chemistry. PMID 29802200 DOI: 10.1074/Jbc.Ra118.001747  0.321
2018 Rangaraju S, Dammer EB, Raza SA, Rathakrishnan P, Xiao H, Gao T, Duong DM, Pennington MW, Lah JJ, Seyfried NT, Levey AI. Identification and therapeutic modulation of a pro-inflammatory subset of disease-associated-microglia in Alzheimer's disease. Molecular Neurodegeneration. 13: 24. PMID 29784049 DOI: 10.1186/S13024-018-0254-8  0.794
2018 Galloway CR, Ravipati K, Singh S, Lebois EP, Cohen RM, Levey AI, Manns JR. Hippocampal place cell dysfunction and the effects of muscarinic M receptor agonism in a rat model of Alzheimer's disease. Hippocampus. PMID 29742799 DOI: 10.1002/Hipo.22961  0.793
2018 Rangaraju S, Raza SA, Li NX, Betarbet R, Dammer EB, Duong D, Lah JJ, Seyfried NT, Levey AI. Differential Phagocytic Properties of CD45Microglia and CD45Brain Mononuclear Phagocytes-Activation and Age-Related Effects. Frontiers in Immunology. 9: 405. PMID 29552013 DOI: 10.3389/Fimmu.2018.00405  0.799
2018 Ping L, Duong DM, Yin L, Gearing M, Lah JJ, Levey AI, Seyfried NT. Global quantitative analysis of the human brain proteome in Alzheimer's and Parkinson's Disease. Scientific Data. 5: 180036. PMID 29533394 DOI: 10.1038/Sdata.2018.36  0.382
2018 Scherer RW, Drye L, Mintzer J, Lanctôt K, Rosenberg P, Herrmann N, Padala P, Brawman-Mintzer O, Burke W, Craft S, Lerner AJ, Levey A, Porsteinsson A, van Dyck CH. The Apathy in Dementia Methylphenidate Trial 2 (ADMET 2): study protocol for a randomized controlled trial. Trials. 19: 46. PMID 29347996 DOI: 10.1186/S13063-017-2406-5  0.326
2017 Maezawa I, Nguyen HM, Di Lucente J, Jenkins DP, Singh V, Hilt S, Kim K, Rangaraju S, Levey AI, Wulff H, Jin LW. Kv1.3 inhibition as a potential microglia-targeted therapy for Alzheimer's disease: preclinical proof of concept. Brain : a Journal of Neurology. PMID 29272333 DOI: 10.1093/Brain/Awx346  0.691
2017 Umoh ME, Dammer EB, Dai J, Duong DM, Lah JJ, Levey AI, Gearing M, Glass JD, Seyfried NT. A proteomic network approach across the ALS-FTD disease spectrum resolves clinical phenotypes and genetic vulnerability in human brain. Embo Molecular Medicine. PMID 29191947 DOI: 10.15252/Emmm.201708202  0.322
2017 Cherry JD, Zeineddin A, Dammer EB, Webster JA, Duong D, Seyfried NT, Levey AI, Alvarez VE, Huber BR, Stein TD, Kiernan PT, McKee AC, Lah JJ, Hales CM. Characterization of Detergent Insoluble Proteome in Chronic Traumatic Encephalopathy. Journal of Neuropathology and Experimental Neurology. PMID 29145658 DOI: 10.1093/Jnen/Nlx100  0.421
2017 Chalermpalanupap T, Schroeder JP, Rorabaugh JM, Liles LC, Lah JJ, Levey AI, Weinshenker D. Locus coeruleus ablation exacerbates cognitive deficits, neuropathology, and lethality in P301S tau transgenic mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 29133432 DOI: 10.1523/Jneurosci.1483-17.2017  0.405
2017 McKenzie AT, Moyon S, Wang M, Katsyv I, Song WM, Zhou X, Dammer EB, Duong DM, Aaker J, Zhao Y, Beckmann N, Wang P, Zhu J, Lah JJ, Seyfried NT, ... Levey AI, et al. Multiscale network modeling of oligodendrocytes reveals molecular components of myelin dysregulation in Alzheimer's disease. Molecular Neurodegeneration. 12: 82. PMID 29110684 DOI: 10.1186/S13024-017-0219-3  0.345
2017 Allen M, Wang X, Burgess JD, Watzlawik J, Serie DJ, Younkin CS, Nguyen T, Malphrus KG, Lincoln S, Carrasquillo MM, Ho C, Chakrabarty P, Strickland S, Murray ME, Swarup V, ... ... Levey AI, et al. Conserved brain myelination networks are altered in Alzheimer's and other neurodegenerative diseases. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 29107053 DOI: 10.1016/J.Jalz.2017.09.012  0.399
2017 An Y, Varma VR, Varma S, Casanova R, Dammer E, Pletnikova O, Chia CW, Egan JM, Ferrucci L, Troncoso J, Levey A, Lah J, Seyfried N, Legido-Quigley C, O'Brien R, et al. Evidence for brain glucose dysregulation in Alzheimer's disease. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 29055815 DOI: 10.1016/J.Jalz.2017.09.011  0.365
2017 Christopher MA, Myrick DA, Barwick BG, Engstrom AK, Porter-Stransky KA, Boss JM, Weinshenker D, Levey AI, Katz DJ. LSD1 protects against hippocampal and cortical neurodegeneration. Nature Communications. 8: 805. PMID 28993646 DOI: 10.1038/S41467-017-00922-9  0.397
2017 Sims R, van der Lee SJ, Naj AC, Bellenguez C, Badarinarayan N, Jakobsdottir J, Kunkle BW, Boland A, Raybould R, Bis JC, Martin ER, Grenier-Boley B, Heilmann-Heimbach S, Chouraki V, Kuzma AB, ... ... Levey AI, et al. Rare coding variants in PLCG2, ABI3, and TREM2 implicate microglial-mediated innate immunity in Alzheimer's disease. Nature Genetics. PMID 28714976 DOI: 10.1038/Ng.3916  0.333
2017 Rangaraju S, Raza SA, Pennati A, Deng Q, Dammer EB, Duong D, Pennington MW, Tansey MG, Lah JJ, Betarbet R, Seyfried NT, Levey AI. A systems pharmacology-based approach to identify novel Kv1.3 channel-dependent mechanisms in microglial activation. Journal of Neuroinflammation. 14: 128. PMID 28651603 DOI: 10.1186/S12974-017-0906-6  0.755
2017 Goldstein FC, Steenland K, Zhao L, Wharton W, Levey AI, Hajjar I. Proton Pump Inhibitors and Risk of Mild Cognitive Impairment and Dementia. Journal of the American Geriatrics Society. PMID 28590010 DOI: 10.1111/Jgs.14956  0.319
2017 Shen Y, Wang H, Sun Q, Yao H, Keegan AP, Mullan M, Wilson J, Lista S, Leyhe T, Laske C, Rujescu D, Levey A, Wallin A, Blennow K, Li R, et al. Increased Plasma Beta-Secretase 1 May Predict Conversion to Alzheimer's Disease Dementia in Individuals With Mild Cognitive Impairment. Biological Psychiatry. PMID 28359566 DOI: 10.1016/J.Biopsych.2017.02.007  0.354
2017 Lebois EP, Schroeder JP, Esparza TJ, Bridges TM, Lindsley CW, Conn PJ, Brody DL, Daniels JS, Levey AI. Disease-Modifying Effects of M1 Muscarinic Acetylcholine Receptor Activation in an Alzheimer's Disease Mouse Model. Acs Chemical Neuroscience. PMID 28230352 DOI: 10.1021/Acschemneuro.6B00278  0.794
2017 Seyfried NT, Dammer EB, Duong DM, Deng Q, Troncoso JC, Thambisetty M, Lah JJ, Levey AI. PROTEIN CO-EXPRESSION NETWORK ANALYSIS IN ASYMPTOMATIC AND SYMPTOMATIC ALZHEIMER'S DISEASE Alzheimer's & Dementia. 13: P554-P555. DOI: 10.1016/J.Jalz.2017.07.155  0.351
2017 Lanctot KL, Scherer R, Li A, Rosenberg PB, Herrmann N, Lerner AJ, Padala PR, Brawman-Mintzer O, van Dyck CH, Porsteinsson AP, Craft S, Levey AI, Burke WJ, Mintzer JE. MEASURING APATHY IN ALZHEIMER'S DISEASE IN THE APATHY IN DEMENTIA METHYLPHENIDATE TRIAL 2 (ADMET 2): A COMPARISON OF INSTRUMENTS Alzheimer's & Dementia. 13: P184. DOI: 10.1016/J.Jalz.2017.07.038  0.336
2016 Seyfried NT, Dammer EB, Swarup V, Nandakumar D, Duong DM, Yin L, Deng Q, Nguyen T, Hales CM, Wingo T, Glass J, Gearing M, Thambisetty M, Troncoso JC, Geschwind DH, ... ... Levey AI, et al. A Multi-network Approach Identifies Protein-Specific Co-expression in Asymptomatic and Symptomatic Alzheimer's Disease. Cell Systems. PMID 27989508 DOI: 10.1016/J.Cels.2016.11.006  0.406
2016 Varma VR, Varma S, An Y, Hohman TJ, Seddighi S, Casanova R, Beri A, Dammer EB, Seyfried NT, Pletnikova O, Moghekar A, Wilson MR, Lah JJ, O'Brien RJ, Levey AI, et al. Alpha-2 macroglobulin in Alzheimer's disease: a marker of neuronal injury through the RCAN1 pathway. Molecular Psychiatry. PMID 27872486 DOI: 10.1038/Mp.2016.206  0.425
2016 Hales CM, Dammer EB, Deng Q, Duong DM, Gearing M, Troncoso JC, Thambisetty M, Lah JJ, Shulman JM, Levey AI, Seyfried NT. Changes in the detergent-insoluble brain proteome linked to amyloid and tau in Alzheimer's Disease progression. Proteomics. PMID 27718298 DOI: 10.1002/Pmic.201600057  0.408
2016 Lebois EP, Trimper JB, Hu C, Levey AI, Manns JR. Effects of selective M1 muscarinic receptor activation on hippocampal spatial representations and neuronal oscillations. Acs Chemical Neuroscience. PMID 27479319 DOI: 10.1021/Acschemneuro.6B00160  0.784
2016 Bernstein AI, Lin Y, Street RC, Lin L, Dai Q, Yu L, Bao H, Gearing M, Lah JJ, Nelson PT, He C, Levey AI, Mullé JG, Duan R, Jin P. 5-hydroxymethylation-associated epigenetic modifiers of Alzheimer's disease modulate Tau-induced neurotoxicity. Human Molecular Genetics. PMID 27060332 DOI: 10.1093/Hmg/Ddw109  0.767
2016 Hu WT, Watts KD, Tailor P, Nguyen TP, Howell JC, Lee RC, Seyfried NT, Gearing M, Hales CM, Levey AI, Lah JJ, Lee EK. CSF complement 3 and factor H are staging biomarkers in Alzheimer's disease. Acta Neuropathologica Communications. 4: 14. PMID 26887322 DOI: 10.1186/S40478-016-0277-8  0.589
2016 Levey AI, Dammer EB, Duong DM, Lah JJ, Seyfried NT. Discovery Of Novel Proteomic Targets For Treatment Of Alzheimer'S Disease Alzheimers & Dementia. 12: 215. DOI: 10.1016/J.Jalz.2016.06.382  0.34
2016 Chalermpalanupap T, Bradner J, Chen T, Jerome C, Schroeder J, Lah JJ, Tansey MG, Levey AI, Weinshenker D. P3-069: Elucidating the Relationship Between Hyperphosphorylated TAU and Locus Coeruleus Degeneration in Alzheimer’s Disease Alzheimer's & Dementia. 12: P844-P844. DOI: 10.1016/J.Jalz.2016.06.1727  0.325
2016 Varma VR, Varma S, An Y, Beri A, Dammer EB, Seyfried NT, Moghekar A, Wilson M, Lah JJ, O’Brien R, Levey AI, Troncoso JC, Albert MS, Thambisetty M. The Acute Phase Protein Alpha-2-Macroglobulin Predicts Risk Of Incident Alzheimer'S Disease And Modulates Tau Pathology Through The Rcan1-Calcineurin Pathway Alzheimers & Dementia. 12: 745. DOI: 10.1016/J.Jalz.2016.06.1554  0.328
2015 Steenland K, Goldstein FC, Levey A, Wharton W. A Meta-Analysis of Alzheimer's Disease Incidence and Prevalence Comparing African-Americans and Caucasians. Journal of Alzheimer's Disease : Jad. PMID 26639973 DOI: 10.3233/Jad-150778  0.359
2015 Zhang Z, Song M, Liu X, Su Kang S, Duong DM, Seyfried NT, Cao X, Cheng L, Sun YE, Ping Yu S, Jia J, Levey AI, Ye K. Delta-secretase cleaves amyloid precursor protein and regulates the pathogenesis in Alzheimer's disease. Nature Communications. 6: 8762. PMID 26549211 DOI: 10.1038/Ncomms9762  0.391
2015 Wharton W, Goldstein FC, Zhao L, Steenland K, Levey AI, Hajjar I. Modulation of Renin-Angiotensin System May Slow Conversion from Mild Cognitive Impairment to Alzheimer's Disease. Journal of the American Geriatrics Society. 63: 1749-56. PMID 26389987 DOI: 10.1111/jgs.13627  0.343
2015 Hajjar I, Levey A. Association Between Angiotensin Receptor Blockers and Longitudinal Decline in Tau in Mild Cognitive Impairment. Jama Neurology. 72: 1069-70. PMID 26368351 DOI: 10.1001/jamaneurol.2015.1001  0.344
2015 Yang Z, Levey A. Gender Differences: A Lifetime Analysis of the Economic Burden of Alzheimer's Disease. Women's Health Issues : Official Publication of the Jacobs Institute of Women's Health. 25: 436-40. PMID 26363924 DOI: 10.1016/j.whi.2015.06.001  0.363
2015 Steinberg S, Stefansson H, Jonsson T, Johannsdottir H, Ingason A, Helgason H, Sulem P, Magnusson OT, Gudjonsson SA, Unnsteinsdottir U, Kong A, Helisalmi S, Soininen H, Lah JJ, ... ... Levey AI, et al. Loss-of-function variants in ABCA7 confer risk of Alzheimer's disease. Nature Genetics. 47: 445-7. PMID 25807283 DOI: 10.1038/Ng.3246  0.343
2015 Hu WT, Watts KD, Shaw LM, Howell JC, Trojanowski JQ, Basra S, Glass JD, Lah JJ, Levey AI. CSF beta-amyloid 1-42 - what are we measuring in Alzheimer's disease? Annals of Clinical and Translational Neurology. 2: 131-9. PMID 25750918 DOI: 10.1002/Acn3.160  0.563
2015 Chen JA, Wang Q, Davis-Turak J, Li Y, Karydas AM, Hsu SC, Sears RL, Chatzopoulou D, Huang AY, Wojta KJ, Klein E, Lee J, Beekly DL, Boxer A, Faber KM, ... ... Levey AI, et al. A multiancestral genome-wide exome array study of Alzheimer disease, frontotemporal dementia, and progressive supranuclear palsy. Jama Neurology. 72: 414-22. PMID 25706306 DOI: 10.1001/Jamaneurol.2014.4040  0.361
2015 Wang LS, Naj AC, Graham RR, Crane PK, Kunkle BW, Cruchaga C, Murcia JD, Cannon-Albright L, Baldwin CT, Zetterberg H, Blennow K, Kukull WA, Faber KM, Schupf N, Norton MC, ... ... Levey AI, et al. Rarity of the Alzheimer disease-protective APP A673T variant in the United States. Jama Neurology. 72: 209-16. PMID 25531812 DOI: 10.1001/Jamaneurol.2014.2157  0.378
2015 Rangaraju S, Gearing M, Jin LW, Levey A. Potassium channel Kv1.3 is highly expressed by microglia in human Alzheimer's disease. Journal of Alzheimer's Disease : Jad. 44: 797-808. PMID 25362031 DOI: 10.3233/Jad-141704  0.684
2015 Dammer EB, Lee AK, Duong DM, Gearing M, Lah JJ, Levey AI, Seyfried NT. Quantitative phosphoproteomics of Alzheimer's disease reveals cross-talk between kinases and small heat shock proteins. Proteomics. 15: 508-19. PMID 25332170 DOI: 10.1002/Pmic.201400189  0.391
2015 Zhang Z, Song M, Liu X, Kang SS, Duong DM, Seyfried NT, Cao X, Cheng L, Sun Y, Yu S, Levey AI, Ye K. Asparagine endopeptidase cleaves amyloid precursor protein and promotes amyloidogenesis in Alzheimer's disease Alzheimers & Dementia. 11. DOI: 10.1016/J.Jalz.2015.08.031  0.398
2015 Dammer EB, Ren R, Duong DM, Lee AK, Gearing M, Lah JJ, Levey AI, Seyfried NT. O4-12-03: Brain phosphoproteome network analysis discriminates Alzheimer's disease from other tauopathies Alzheimer's & Dementia. 11: P300-P300. DOI: 10.1016/J.Jalz.2015.07.415  0.324
2015 Dammer EB, Duong DM, Yin L, Swarup V, Parikshak N, Coppola G, Geschwind DH, Troncoso JC, Thambisetty M, Seyfried NT, Lah JJ, Levey AI. O4-12-02: Protein co-expression network analysis in Alzheimer's disease Alzheimer's & Dementia. 11: P299-P299. DOI: 10.1016/J.Jalz.2015.07.414  0.328
2015 Wharton W, Goldstein FC, Zhao L, Steenland K, Levey AI, Hajjar I. O4-09-02: Certain antihypertensives may slow the conversion from mild cognitive impairment to Alzheimer's disease Alzheimer's & Dementia. 11: P290-P290. DOI: 10.1016/J.Jalz.2015.07.394  0.312
2014 Ren RJ, Dammer EB, Wang G, Seyfried NT, Levey AI. Proteomics of protein post-translational modifications implicated in neurodegeneration. Translational Neurodegeneration. 3: 23. PMID 25671099 DOI: 10.1186/2047-9158-3-23  0.306
2014 Diner I, Hales CM, Bishof I, Rabenold L, Duong DM, Yi H, Laur O, Gearing M, Troncoso J, Thambisetty M, Lah JJ, Levey AI, Seyfried NT. Aggregation properties of the small nuclear ribonucleoprotein U1-70K in Alzheimer disease. The Journal of Biological Chemistry. 289: 35296-313. PMID 25355317 DOI: 10.1074/Jbc.M114.562959  0.308
2014 Zhang Z, Song M, Liu X, Kang SS, Kwon IS, Duong DM, Seyfried NT, Hu WT, Liu Z, Wang JZ, Cheng L, Sun YE, Yu SP, Levey AI, Ye K. Cleavage of tau by asparagine endopeptidase mediates the neurofibrillary pathology in Alzheimer's disease. Nature Medicine. 20: 1254-62. PMID 25326800 DOI: 10.1038/Nm.3700  0.596
2014 Naj AC, Jun G, Reitz C, Kunkle BW, Perry W, Park YS, Beecham GW, Rajbhandary RA, Hamilton-Nelson KL, Wang LS, Kauwe JS, Huentelman MJ, Myers AJ, Bird TD, Boeve BF, ... ... Levey AI, et al. Effects of multiple genetic loci on age at onset in late-onset Alzheimer disease: a genome-wide association study. Jama Neurology. 71: 1394-404. PMID 25199842 DOI: 10.1001/Jamaneurol.2014.1491  0.304
2014 Richardson JR, Levey AI, German DC. Elevated serum DDE and risk for Alzheimer disease--reply. Jama Neurology. 71: 1056. PMID 25111214 DOI: 10.1001/jamaneurol.2014.1548  0.549
2014 Richardson JR, German D, Levey A. Alzheimer disease risk factors. Jama Neurology. 71: 1051. PMID 25111206 DOI: 10.1001/jamaneurol.2014.1525  0.546
2014 Bai B, Chen PC, Hales CM, Wu Z, Pagala V, High AA, Levey AI, Lah JJ, Peng J. Integrated approaches for analyzing U1-70K cleavage in Alzheimer's disease. Journal of Proteome Research. 13: 4526-34. PMID 24902715 DOI: 10.1021/Pr5003593  0.311
2014 Hales CM, Seyfried NT, Dammer EB, Duong D, Yi H, Gearing M, Troncoso JC, Mufson EJ, Thambisetty M, Levey AI, Lah JJ. U1 small nuclear ribonucleoproteins (snRNPs) aggregate in Alzheimer's disease due to autosomal dominant genetic mutations and trisomy 21. Molecular Neurodegeneration. 9: 15. PMID 24773620 DOI: 10.1186/1750-1326-9-15  0.363
2014 Sun Q, Hampel H, Blennow K, Lista S, Levey A, Tang B, Li R, Shen Y. Increased plasma TACE activity in subjects with mild cognitive impairment and patients with Alzheimer's disease. Journal of Alzheimer's Disease : Jad. 41: 877-86. PMID 24685635 DOI: 10.3233/JAD-140177  0.37
2014 Hales CM, Dammer EB, Diner I, Yi H, Seyfried NT, Gearing M, Glass JD, Montine TJ, Levey AI, Lah JJ. Aggregates of small nuclear ribonucleic acids (snRNAs) in Alzheimer's disease. Brain Pathology (Zurich, Switzerland). 24: 344-51. PMID 24571648 DOI: 10.1111/Bpa.12133  0.386
2014 Richardson JR, Roy A, Shalat SL, von Stein RT, Hossain MM, Buckley B, Gearing M, Levey AI, German DC. Elevated serum pesticide levels and risk for Alzheimer disease. Jama Neurology. 71: 284-90. PMID 24473795 DOI: 10.1001/Jamaneurol.2013.6030  0.583
2013 Herskowitz JH, Feng Y, Mattheyses AL, Hales CM, Higginbotham LA, Duong DM, Montine TJ, Troncoso JC, Thambisetty M, Seyfried NT, Levey AI, Lah JJ. Pharmacologic inhibition of ROCK2 suppresses amyloid-β production in an Alzheimer's disease mouse model. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 33: 19086-98. PMID 24305806 DOI: 10.1523/Jneurosci.2508-13.2013  0.422
2013 Hu WT, Watts K, Grossman M, Glass J, Lah JJ, Hales C, Shelnutt M, Van Deerlin V, Trojanowski JQ, Levey AI. Reduced CSF p-Tau181 to Tau ratio is a biomarker for FTLD-TDP. Neurology. 81: 1945-52. PMID 24174584 DOI: 10.1212/01.Wnl.0000436625.63650.27  0.548
2013 Hales CM, Rees H, Seyfried NT, Dammer EB, Duong DM, Gearing M, Montine TJ, Troncoso JC, Thambisetty M, Levey AI, Lah JJ, Wingo TS. Abnormal gephyrin immunoreactivity associated with Alzheimer disease pathologic changes. Journal of Neuropathology and Experimental Neurology. 72: 1009-15. PMID 24128675 DOI: 10.1097/01.Jnen.0000435847.59828.Db  0.417
2013 Bai B, Hales CM, Chen PC, Gozal Y, Dammer EB, Fritz JJ, Wang X, Xia Q, Duong DM, Street C, Cantero G, Cheng D, Jones DR, Wu Z, Li Y, ... ... Levey A, et al. U1 small nuclear ribonucleoprotein complex and RNA splicing alterations in Alzheimer's disease. Proceedings of the National Academy of Sciences of the United States of America. 110: 16562-7. PMID 24023061 DOI: 10.1073/Pnas.1310249110  0.709
2013 Dammer EB, Duong DM, Diner I, Gearing M, Feng Y, Lah JJ, Levey AI, Seyfried NT. Neuron enriched nuclear proteome isolated from human brain. Journal of Proteome Research. 12: 3193-206. PMID 23768213 DOI: 10.1021/Pr400246T  0.344
2013 Donovan LE, Dammer EB, Duong DM, Hanfelt JJ, Levey AI, Seyfried NT, Lah JJ. Exploring the potential of the platelet membrane proteome as a source of peripheral biomarkers for Alzheimer's disease. Alzheimer's Research & Therapy. 5: 32. PMID 23764030 DOI: 10.1186/Alzrt186  0.357
2013 Chalermpalanupap T, Kinkead B, Hu WT, Kummer MP, Hammerschmidt T, Heneka MT, Weinshenker D, Levey AI. Targeting norepinephrine in mild cognitive impairment and Alzheimer's disease. Alzheimer's Research & Therapy. 5: 21. PMID 23634965 DOI: 10.1186/Alzrt175  0.597
2013 Hu WT, Shelnutt M, Wilson A, Yarab N, Kelly C, Grossman M, Libon DJ, Khan J, Lah JJ, Levey AI, Glass J. Behavior matters--cognitive predictors of survival in amyotrophic lateral sclerosis. Plos One. 8: e57584. PMID 23460879 DOI: 10.1371/Journal.Pone.0057584  0.496
2013 Pranski EL, Dalal NV, Sanford CV, Herskowitz JH, Gearing M, Lazo C, Miller GW, Lah JJ, Levey AI, Betarbet RS. RING finger protein 11 (RNF11) modulates susceptibility to 6-OHDA-induced nigral degeneration and behavioral deficits through NF-κB signaling in dopaminergic cells. Neurobiology of Disease. 54: 264-79. PMID 23318928 DOI: 10.1016/J.Nbd.2012.12.018  0.515
2013 Zola SM, Manzanares CM, Clopton P, Lah JJ, Levey AI. A behavioral task predicts conversion to mild cognitive impairment and Alzheimer's disease. American Journal of Alzheimer's Disease and Other Dementias. 28: 179-84. PMID 23271330 DOI: 10.1177/1533317512470484  0.321
2013 Jonsson T, Stefansson H, Steinberg S, Jonsdottir I, Jonsson PV, Snaedal J, Bjornsson S, Huttenlocher J, Levey AI, Lah JJ, Rujescu D, Hampel H, Giegling I, Andreassen OA, Engedal K, et al. Variant of TREM2 associated with the risk of Alzheimer's disease. The New England Journal of Medicine. 368: 107-16. PMID 23150908 DOI: 10.1056/Nejmoa1211103  0.369
2013 Higginbotham L, Donovan L, Duong D, Dammer E, Schantz A, Montine T, Lah J, Levey A, Seyfried N. O2-08-06: Analysis of the synapse-rich brain proteome reveals potential markers of asymptomatic Alzheimer's disease Alzheimer's & Dementia. 9: P331-P331. DOI: 10.1016/J.Jalz.2013.04.182  0.343
2013 Herskowitz J, Feng Y, Higginbotham L, Seyfried N, Levey A, Lah J. Selective drug inhibition of rho kinase II (ROCK2) reduces beta-amyloid production in the brain Alzheimers & Dementia. 9: 153. DOI: 10.1016/J.Jalz.2013.04.115  0.316
2012 Dalal NV, Pranski EL, Tansey MG, Lah JJ, Levey AI, Betarbet RS. RNF11 modulates microglia activation through NF-κB signalling cascade. Neuroscience Letters. 528: 174-9. PMID 22975135 DOI: 10.1016/J.Neulet.2012.08.060  0.302
2012 Sager KL, Wuu J, Herskowitz JH, Mufson EJ, Levey AI, Lah JJ. Neuronal LR11 expression does not differentiate between clinically-defined Alzheimer's disease and control brains. Plos One. 7: e40527. PMID 22927900 DOI: 10.1371/Journal.Pone.0040527  0.398
2012 Hatcher-Martin JM, Gearing M, Steenland K, Levey AI, Miller GW, Pennell KD. Association between polychlorinated biphenyls and Parkinson's disease neuropathology. Neurotoxicology. 33: 1298-304. PMID 22906799 DOI: 10.1016/J.Neuro.2012.08.002  0.523
2012 Dammer EB, Fallini C, Gozal YM, Duong DM, Rossoll W, Xu P, Lah JJ, Levey AI, Peng J, Bassell GJ, Seyfried NT. Coaggregation of RNA-binding proteins in a model of TDP-43 proteinopathy with selective RGG motif methylation and a role for RRM1 ubiquitination. Plos One. 7: e38658. PMID 22761693 DOI: 10.1371/Journal.Pone.0038658  0.67
2012 Herskowitz JH, Gozal YM, Duong DM, Dammer EB, Gearing M, Ye K, Lah JJ, Peng J, Levey AI, Seyfried NT. Asparaginyl endopeptidase cleaves TDP-43 in brain. Proteomics. 12: 2455-63. PMID 22718532 DOI: 10.1002/Pmic.201200006  0.675
2012 Herskowitz JH, Offe K, Deshpande A, Kahn RA, Levey AI, Lah JJ. GGA1-mediated endocytic traffic of LR11/SorLA alters APP intracellular distribution and amyloid-β production. Molecular Biology of the Cell. 23: 2645-57. PMID 22621900 DOI: 10.1091/Mbc.E12-01-0014  0.799
2012 Coppola G, Chinnathambi S, Lee JJ, Dombroski BA, Baker MC, Soto-Ortolaza AI, Lee SE, Klein E, Huang AY, Sears R, Lane JR, Karydas AM, Kenet RO, Biernat J, Wang LS, ... ... Levey AI, et al. Evidence for a role of the rare p.A152T variant in MAPT in increasing the risk for FTD-spectrum and Alzheimer's diseases. Human Molecular Genetics. 21: 3500-12. PMID 22556362 DOI: 10.1093/Hmg/Dds161  0.372
2012 Donovan LE, Higginbotham L, Dammer EB, Gearing M, Rees HD, Xia Q, Duong DM, Seyfried NT, Lah JJ, Levey AI. Analysis of a membrane-enriched proteome from postmortem human brain tissue in Alzheimer's disease. Proteomics. Clinical Applications. 6: 201-11. PMID 22532456 DOI: 10.1002/Prca.201100068  0.392
2012 Pranski EL, Dalal NV, Herskowitz JH, Orr AL, Roesch LA, Fritz JJ, Heilman C, Lah JJ, Levey AI, Betarbet RS. Neuronal RING finger protein 11 (RNF11) regulates canonical NF-κB signaling. Journal of Neuroinflammation. 9: 67. PMID 22507528 DOI: 10.1186/1742-2094-9-67  0.322
2012 Seyfried NT, Gozal YM, Donovan LE, Herskowitz JH, Dammer EB, Xia Q, Ku L, Chang J, Duong DM, Rees HD, Cooper DS, Glass JD, Gearing M, Tansey MG, Lah JJ, ... ... Levey AI, et al. Quantitative analysis of the detergent-insoluble brain proteome in frontotemporal lobar degeneration using SILAC internal standards. Journal of Proteome Research. 11: 2721-38. PMID 22416763 DOI: 10.1021/Pr2010814  0.685
2012 Steenland K, Levey AI, Goldstein FC. Hypertension and Alzheimer disease: is there a link? Epidemiology (Cambridge, Mass.). 23: 176-7; author reply . PMID 22157315 DOI: 10.1097/Ede.0B013E31823B679C  0.338
2012 Wingo TS, Lah JJ, Levey AI, Cutler DJ. Autosomal recessive causes likely in early-onset Alzheimer disease. Archives of Neurology. 69: 59-64. PMID 21911656 DOI: 10.1001/Archneurol.2011.221  0.353
2012 Wingo TS, Rosen A, Cutler DJ, Lah JJ, Levey AI. Paraoxonase-1 polymorphisms in Alzheimer's disease, Parkinson's disease, and AD-PD spectrum diseases. Neurobiology of Aging. 33: 204.e13-5. PMID 20947215 DOI: 10.1016/J.Neurobiolaging.2010.08.010  0.326
2012 Hu W, Basra S, Watts K, Glass J, Lah J, Levey A. Cerebrospinal Fluid beta-Amyloid 1-42 Solubility Is Influenced by Apolipoproteins E and J (S14.002) Neurology. 78: S14.002-S14.002. DOI: 10.1212/Wnl.78.1_Meetingabstracts.S14.002  0.51
2012 Richardson J, Roy A, Shalat S, Buckley B, Winnik B, Gearing M, Levey AI, German D. P-073 Epidemiology. 23: 1. DOI: 10.1097/01.Ede.0000417080.51582.43  0.471
2012 German D, Roy A, Shalat S, Buckley B, Gearing M, Levey A, Richardson J. P3-128: A DDT metabolite is elevated in the serum of Alzheimer's disease patients Alzheimer's & Dementia. 8: P496-P496. DOI: 10.1016/J.Jalz.2012.05.1348  0.556
2011 Gozal YM, Seyfried NT, Gearing M, Glass JD, Heilman CJ, Wuu J, Duong DM, Cheng D, Xia Q, Rees HD, Fritz JJ, Cooper DS, Peng J, Levey AI, Lah JJ. Aberrant septin 11 is associated with sporadic frontotemporal lobar degeneration. Molecular Neurodegeneration. 6: 82. PMID 22126117 DOI: 10.1186/1750-1326-6-82  0.695
2011 Hata S, Fujishige S, Araki Y, Taniguchi M, Urakami K, Peskind E, Akatsu H, Araseki M, Yamamoto K, Martins RN, Maeda M, Nishimura M, Levey A, Chung KA, Montine T, et al. Alternative processing of γ-secretase substrates in common forms of mild cognitive impairment and Alzheimer's disease: evidence for γ-secretase dysfunction. Annals of Neurology. 69: 1026-31. PMID 21681798 DOI: 10.1002/Ana.22343  0.356
2011 Richardson JR, Roy A, Shalat SL, Buckley B, Winnik B, Gearing M, Levey AI, Factor SA, O'Suilleabhain P, German DC. β-Hexachlorocyclohexane levels in serum and risk of Parkinson's disease. Neurotoxicology. 32: 640-5. PMID 21620887 DOI: 10.1016/J.Neuro.2011.04.002  0.495
2011 Gozal YM, Dammer EB, Duong DM, Cheng D, Gearing M, Rees HD, Peng J, Lah JJ, Levey AI. Proteomic analysis of hippocampal dentate granule cells in frontotemporal lobar degeneration: application of laser capture technology. Frontiers in Neurology. 2: 24. PMID 21577247 DOI: 10.3389/Fneur.2011.00024  0.683
2011 Dammer EB, Na CH, Xu P, Seyfried NT, Duong DM, Cheng D, Gearing M, Rees H, Lah JJ, Levey AI, Rush J, Peng J. Polyubiquitin linkage profiles in three models of proteolytic stress suggest the etiology of Alzheimer disease. The Journal of Biological Chemistry. 286: 10457-65. PMID 21278249 DOI: 10.1074/Jbc.M110.149633  0.342
2011 Wang L, Goldstein FC, Levey AI, Lah JJ, Meltzer CC, Holder CA, Mao H. White matter hyperintensities and changes in white matter integrity in patients with Alzheimer's disease. Neuroradiology. 53: 373-81. PMID 21152911 DOI: 10.1007/S00234-010-0806-2  0.337
2011 Herskowitz JH, Seyfried NT, Gearing M, Kahn RA, Peng J, Levey AI, Lah JJ. Rho kinase II phosphorylation of the lipoprotein receptor LR11/SORLA alters amyloid-beta production. The Journal of Biological Chemistry. 286: 6117-27. PMID 21147781 DOI: 10.1074/Jbc.M110.167239  0.541
2011 Wingo T, Levey A, Lah J, Cutler D. Early-onset Alzheimer's disease likely has autosomal recessive causes Alzheimers & Dementia. 7. DOI: 10.1016/J.Jalz.2011.09.088  0.352
2011 Zola S, Manzanares C, Levey A, Lah J. P3-109: Predicting the onset of Alzheimer's disease with a behavioral task Alzheimer's & Dementia. 7: S549-S549. DOI: 10.1016/J.Jalz.2011.05.1549  0.301
2010 Herskowitz JH, Seyfried NT, Duong DM, Xia Q, Rees HD, Gearing M, Peng J, Lah JJ, Levey AI. Phosphoproteomic analysis reveals site-specific changes in GFAP and NDRG2 phosphorylation in frontotemporal lobar degeneration. Journal of Proteome Research. 9: 6368-79. PMID 20886841 DOI: 10.1021/Pr100666C  0.37
2010 Davis AA, Heilman CJ, Brady AE, Miller NR, Fuerstenau-Sharp M, Hanson BJ, Lindsley CW, Conn PJ, Lah JJ, Levey AI. Differential effects of allosteric M(1) muscarinic acetylcholine receptor agonists on receptor activation, arrestin 3 recruitment, and receptor downregulation. Acs Chemical Neuroscience. 1: 542-551. PMID 20835371 DOI: 10.1021/Cn100011E  0.677
2010 Gandy S, Simon AJ, Steele JW, Lublin AL, Lah JJ, Walker LC, Levey AI, Krafft GA, Levy E, Checler F, Glabe C, Bilker WB, Abel T, Schmeidler J, Ehrlich ME. Days to criterion as an indicator of toxicity associated with human Alzheimer amyloid-beta oligomers. Annals of Neurology. 68: 220-30. PMID 20641005 DOI: 10.1002/Ana.22052  0.335
2010 Steenland K, MacNeil J, Seals R, Levey A. Factors affecting survival of patients with neurodegenerative disease Neuroepidemiology. 35: 28-35. PMID 20389122 DOI: 10.1159/000306055  0.331
2010 Davis AA, Fritz JJ, Wess J, Lah JJ, Levey AI. Deletion of M1 muscarinic acetylcholine receptors increases amyloid pathology in vitro and in vivo. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 30: 4190-6. PMID 20335454 DOI: 10.1523/Jneurosci.6393-09.2010  0.673
2010 Jeon J, Dencker D, Wörtwein G, Woldbye DP, Cui Y, Davis AA, Levey AI, Schütz G, Sager TN, Mørk A, Li C, Deng CX, Fink-Jensen A, Wess J. A subpopulation of neuronal M4 muscarinic acetylcholine receptors plays a critical role in modulating dopamine-dependent behaviors. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 30: 2396-405. PMID 20147565 DOI: 10.1523/Jneurosci.3843-09.2010  0.625
2010 Prior M, Shi Q, Hu X, He W, Levey A, Yan R. RTN/Nogo in forming Alzheimer's neuritic plaques. Neuroscience and Biobehavioral Reviews. 34: 1201-6. PMID 20144652 DOI: 10.1016/J.Neubiorev.2010.01.017  0.413
2010 Seyfried NT, Gozal YM, Dammer EB, Xia Q, Duong DM, Cheng D, Lah JJ, Levey AI, Peng J. Multiplex SILAC analysis of a cellular TDP-43 proteinopathy model reveals protein inclusions associated with SUMOylation and diverse polyubiquitin chains. Molecular & Cellular Proteomics : McP. 9: 705-18. PMID 20047951 DOI: 10.1074/Mcp.M800390-Mcp200  0.694
2010 Lamar M, Libon DJ, Ashley AV, Lah JJ, Levey AI, Goldstein FC. The impact of vascular comorbidities on qualitative error analysis of executive impairment in Alzheimer's disease. Journal of the International Neuropsychological Society : Jins. 16: 77-83. PMID 19835657 DOI: 10.1017/S1355617709990981  0.333
2010 Steele JW, Simon AJ, Lublin AL, Lah JJ, Walker LC, Levey AI, Krafft GA, Levy E, Glabe C, Bilker W, Abel T, Schmeidler J, Ehrlich ME, Gandy S. Evidence for dose-dependent neurotoxicity of amyloid-β oligomers/Aβ-derived diffusible ligands generated from physiological processing of transgenic human APP in situ in mouse brain Alzheimers & Dementia. 6. DOI: 10.1016/J.Jalz.2010.05.737  0.306
2009 Shirey JK, Brady AE, Jones PJ, Davis AA, Bridges TM, Kennedy JP, Jadhav SB, Menon UN, Xiang Z, Watson ML, Christian EP, Doherty JJ, Quirk MC, Snyder DH, Lah JJ, ... Levey AI, et al. A selective allosteric potentiator of the M1 muscarinic acetylcholine receptor increases activity of medial prefrontal cortical neurons and restores impairments in reversal learning. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 29: 14271-86. PMID 19906975 DOI: 10.1523/Jneurosci.3930-09.2009  0.702
2009 Gozal YM, Duong DM, Gearing M, Cheng D, Hanfelt JJ, Funderburk C, Peng J, Lah JJ, Levey AI. Proteomics analysis reveals novel components in the detergent-insoluble subproteome in Alzheimer's disease. Journal of Proteome Research. 8: 5069-79. PMID 19746990 DOI: 10.1021/Pr900474T  0.717
2009 Mount DL, Ashley AV, Lah JJ, Levey AI, Goldstein FC. Is ApoE epsilon4 associated with cognitive functioning in African Americans diagnosed with Alzheimer Disease? An exploratory study. Southern Medical Journal. 102: 890-3. PMID 19668025 DOI: 10.1097/Smj.0B013E3181B21B82  0.35
2009 Steenland K, MacNeil J, Vega I, Levey A. Recent trends in Alzheimer disease mortality in the United States, 1999 to 2004 Alzheimer Disease and Associated Disorders. 23: 165-170. PMID 19484918 DOI: 10.1097/Wad.0B013E3181902C3E  0.304
2009 Hata S, Maeda M, Nishimura M, Levey A, Chung KA, Montine T, Fagan A, Goate A, Bateman R, Holtzman DM, Nakaya T, Gandy S, Suzuki T. P2-190: p3-Alc peptides produced by covariant processing of Alcadein and APP implicate γ-secretase dysfunction in sporadic Alzheimer's disease Alzheimer's & Dementia. 5: P316-P317. DOI: 10.1016/J.Jalz.2009.04.502  0.321
2008 Goldstein FC, Ashley AV, Endeshaw YW, Hanfelt J, Lah JJ, Levey AI. Effects of hypertension and hypercholesterolemia on cognitive functioning in patients with alzheimer disease. Alzheimer Disease and Associated Disorders. 22: 336-42. PMID 19068499 DOI: 10.1097/Wad.0B013E318188E80D  0.352
2008 Dodson SE, Andersen OM, Karmali V, Fritz JJ, Cheng D, Peng J, Levey AI, Willnow TE, Lah JJ. Loss of LR11/SORLA enhances early pathology in a mouse model of amyloidosis: evidence for a proximal role in Alzheimer's disease. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 28: 12877-86. PMID 19036982 DOI: 10.1523/Jneurosci.4582-08.2008  0.432
2008 Figueroa R, Steenland K, MacNeil JR, Levey AI, Vega IE. Geographical differences in the occurrence of Alzheimer's disease mortality: United States versus Puerto Rico. American Journal of Alzheimer's Disease and Other Dementias. 23: 462-9. PMID 18955725 DOI: 10.1177/1533317508321909  0.317
2008 Schaffer BA, Bertram L, Miller BL, Mullin K, Weintraub S, Johnson N, Bigio EH, Mesulam M, Wiedau-Pazos M, Jackson GR, Cummings JL, Cantor RM, Levey AI, Tanzi RE, Geschwind DH. Association of GSK3B with Alzheimer disease and frontotemporal dementia. Archives of Neurology. 65: 1368-74. PMID 18852354 DOI: 10.1001/Archneur.65.10.1368  0.36
2008 Jones CK, Brady AE, Davis AA, Xiang Z, Bubser M, Tantawy MN, Kane AS, Bridges TM, Kennedy JP, Bradley SR, Peterson TE, Ansari MS, Baldwin RM, Kessler RM, Deutch AY, ... ... Levey AI, et al. Novel selective allosteric activator of the M1 muscarinic acetylcholine receptor regulates amyloid processing and produces antipsychotic-like activity in rats. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 28: 10422-33. PMID 18842902 DOI: 10.1523/Jneurosci.1850-08.2008  0.694
2008 Betarbet R, Anderson LR, Gearing M, Hodges TR, Fritz JJ, Lah JJ, Levey AI. Fas-associated factor 1 and Parkinson's disease. Neurobiology of Disease. 31: 309-15. PMID 18573343 DOI: 10.1016/J.Nbd.2008.05.006  0.697
2008 Xia Q, Cheng D, Duong DM, Gearing M, Lah JJ, Levey AI, Peng J. Phosphoproteomic analysis of human brain by calcium phosphate precipitation and mass spectrometry. Journal of Proteome Research. 7: 2845-51. PMID 18510355 DOI: 10.1021/Pr8000496  0.347
2008 Xia Q, Liao L, Cheng D, Duong DM, Gearing M, Lah JJ, Levey AI, Peng J. Proteomic identification of novel proteins associated with Lewy bodies. Frontiers in Bioscience : a Journal and Virtual Library. 13: 3850-6. PMID 18508479 DOI: 10.2741/2973  0.308
2008 Agca C, Fritz JJ, Walker LC, Levey AI, Chan AW, Lah JJ, Agca Y. Development of transgenic rats producing human beta-amyloid precursor protein as a model for Alzheimer's disease: transgene and endogenous APP genes are regulated tissue-specifically. Bmc Neuroscience. 9: 28. PMID 18302776 DOI: 10.1186/1471-2202-9-28  0.369
2008 Shrivastava-Ranjan P, Faundez V, Fang G, Rees H, Lah JJ, Levey AI, Kahn RA. Mint3/X11gamma is an ADP-ribosylation factor-dependent adaptor that regulates the traffic of the Alzheimer's Precursor protein from the trans-Golgi network. Molecular Biology of the Cell. 19: 51-64. PMID 17959829 DOI: 10.1091/Mbc.E07-05-0465  0.536
2008 Levey A. S3-04-02: Muscarinic acetylcholine receptor subtype regulation of amyloid precursor protein processing Alzheimers & Dementia. 4. DOI: 10.1016/J.Jalz.2008.05.393  0.354
2007 Dodson SE, Heilman CJ, Kahn RA, Levey AI. Production of antisera using fusion proteins. Current Protocols in Neuroscience / Editorial Board, Jacqueline N. Crawley ... [Et Al.]. Unit 5.7. PMID 18428660 DOI: 10.1002/0471142301.Ns0507S40  0.476
2007 Anderson LR, Betarbet R, Gearing M, Gulcher J, Hicks AA, Stefánsson K, Lah JJ, Levey AI. PARK10 candidate RNF11 is expressed by vulnerable neurons and localizes to Lewy bodies in Parkinson disease brain. Journal of Neuropathology and Experimental Neurology. 66: 955-64. PMID 17917589 DOI: 10.1097/Nen.0B013E3181567F17  0.704
2007 Sager KL, Wuu J, Leurgans SE, Rees HD, Gearing M, Mufson EJ, Levey AI, Lah JJ. Neuronal LR11/sorLA expression is reduced in mild cognitive impairment. Annals of Neurology. 62: 640-7. PMID 17721864 DOI: 10.1002/Ana.21190  0.394
2007 Lee JH, Bliwise DL, Ansari FP, Goldstein FC, Cellar JS, Lah JJ, Levey AI. Daytime sleepiness and functional impairment in Alzheimer disease. The American Journal of Geriatric Psychiatry : Official Journal of the American Association For Geriatric Psychiatry. 15: 620-6. PMID 17586786 DOI: 10.1097/Jgp.0B013E3180381521  0.319
2007 Hu X, Shi Q, Zhou X, He W, Yi H, Yin X, Gearing M, Levey A, Yan R. Transgenic mice overexpressing reticulon 3 develop neuritic abnormalities. The Embo Journal. 26: 2755-67. PMID 17476306 DOI: 10.1038/Sj.Emboj.7601707  0.391
2007 Olzmann JA, Bordelon JR, Muly EC, Rees HD, Levey AI, Li L, Chin LS. Selective enrichment of DJ-1 protein in primate striatal neuronal processes: implications for Parkinson's disease. The Journal of Comparative Neurology. 500: 585-99. PMID 17120294 DOI: 10.1002/Cne.21191  0.363
2007 Bazalakova MH, Wright J, Schneble EJ, McDonald MP, Heilman CJ, Levey AI, Blakely RD. Deficits in acetylcholine homeostasis, receptors and behaviors in choline transporter heterozygous mice. Genes, Brain, and Behavior. 6: 411-24. PMID 17010154 DOI: 10.1111/J.1601-183X.2006.00269.X  0.337
2006 Gozal YM, Cheng D, Duong DM, Lah JJ, Levey AI, Peng J. Merger of laser capture microdissection and mass spectrometry: a window into the amyloid plaque proteome. Methods in Enzymology. 412: 77-93. PMID 17046653 DOI: 10.1016/S0076-6879(06)12006-6  0.665
2006 Levey A, Lah J, Goldstein F, Steenland K, Bliwise D. Mild cognitive impairment: an opportunity to identify patients at high risk for progression to Alzheimer's disease. Clinical Therapeutics. 28: 991-1001. PMID 16990077 DOI: 10.1016/J.Clinthera.2006.07.006  0.357
2006 Dodson SE, Gearing M, Lippa CF, Montine TJ, Levey AI, Lah JJ. LR11/SorLA expression is reduced in sporadic Alzheimer disease but not in familial Alzheimer disease. Journal of Neuropathology and Experimental Neurology. 65: 866-72. PMID 16957580 DOI: 10.1097/01.Jnen.0000228205.19915.20  0.414
2006 McClatchy DB, Fang G, Levey AI. Elongation factor 1A family regulates the recycling of the M4 muscarinic acetylcholine receptor. Neurochemical Research. 31: 975-88. PMID 16845586 DOI: 10.1007/s11064-006-9103-1  0.681
2006 Loreti S, Vilaró MT, Visentin S, Rees H, Levey AI, Tata AM. Rat Schwann cells express M1-M4 muscarinic receptor subtypes. Journal of Neuroscience Research. 84: 97-105. PMID 16634060 DOI: 10.1002/jnr.20874  0.313
2006 Choi J, Sullards MC, Olzmann JA, Rees HD, Weintraub ST, Bostwick DE, Gearing M, Levey AI, Chin LS, Li L. Oxidative damage of DJ-1 is linked to sporadic Parkinson and Alzheimer diseases. The Journal of Biological Chemistry. 281: 10816-24. PMID 16517609 DOI: 10.1074/Jbc.M509079200  0.327
2006 Offe K, Dodson SE, Shoemaker JT, Fritz JJ, Gearing M, Levey AI, Lah JJ. The lipoprotein receptor LR11 regulates amyloid beta production and amyloid precursor protein traffic in endosomal compartments. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 26: 1596-603. PMID 16452683 DOI: 10.1523/Jneurosci.4946-05.2006  0.813
2006 Ping L, Duong D, Dammer EB, Gearing M, Lah JJ, Levey AI, Seyfried NT. P2-217: INTEGRATED PROTEOMICS AND PHOSPHOPROTEOMICS REVEAL NETWORKS LINKED TO ALZHEIMER'S DISEASE RISK Alzheimer's & Dementia. 14: P752-P752. DOI: 10.1016/J.Jalz.2018.06.905  0.318
2006 Chalermpalanupap T, Rorabaugh JM, DePuy SD, Rasmussen K, Lah JJ, Levey AI, Cohen RM, Weinshenker D. F4-07-04: THE CONSEQUENCES OF TAU IN THE LOCUS COERULEUS ON ALZHEIMER'S DISEASE Alzheimer's & Dementia. 14: P1394-P1394. DOI: 10.1016/J.Jalz.2018.06.2891  0.334
2006 Raza SA, Gao T, Dammer EB, Xiao H, Lah JJ, Seyfried NT, Levey AI, Rangaraju S. O2-01-01: A TRANSCRIPTOMIC LANDSCAPE OF MICROGLIAL ACTIVATION IN ALZHEIMER'S DISEASE Alzheimer's & Dementia. 14: P608-P608. DOI: 10.1016/J.Jalz.2018.06.2639  0.33
2006 Abreha M, Dammer EB, Ping L, Duong D, Lah JJ, Levey AI, Seyfried NT. P3-191: COMPREHENSIVE MAPPING OF ALZHEIMER'S DISEASE BRAIN UBIQUITYLOME Alzheimer's & Dementia. 14: P1140-P1140. DOI: 10.1016/J.Jalz.2018.06.1549  0.341
2006 Walker LC, Rosen R, Rees H, Stephens S, Carter S, Fritz J, Chan A, Bogush A, Gandy S, Ehrlich M, Levey A, Smith Y, Lah J. AbstractPoster presentation: Sunday posterP1-017: Focal lentivirus-mediated expression of transgenic tau and APP Alzheimers & Dementia. 2. DOI: 10.1016/J.Jalz.2006.05.392  0.316
2006 Lamar M, Goldstein F, Libon DJ, Ashley AV, Lah JJ, Levey AI. P3-055: The role of specific vascular biomarkers on executive functioning in Alzheimer's disease Alzheimer's & Dementia. 2: S388-S388. DOI: 10.1016/J.Jalz.2006.05.1322  0.344
2005 Petersen RC, Thomas RG, Grundman M, Bennett D, Doody R, Ferris S, Galasko D, Jin S, Kaye J, Levey A, Pfeiffer E, Sano M, van Dyck CH, Thal LJ. Vitamin E and donepezil for the treatment of mild cognitive impairment. The New England Journal of Medicine. 352: 2379-88. PMID 15829527 DOI: 10.1056/Nejmoa050151  0.327
2005 Choi J, Rees HD, Weintraub ST, Levey AI, Chin LS, Li L. Oxidative modifications and aggregation of Cu,Zn-superoxide dismutase associated with Alzheimer and Parkinson diseases. The Journal of Biological Chemistry. 280: 11648-55. PMID 15659387 DOI: 10.1074/jbc.M414327200  0.347
2005 Thal LJ, Thomas RG, Grundman M, Bennett DA, Doody RS, Ferris SH, Galasko DR, Jin S, Levey AI, Petersen RC. [O2-01-01]: Donepezil and vitamin E in the progression of mild cognitive impairment to Alzheimer's disease: A hazard-ratio analysis Alzheimer's & Dementia. 1: S93-S94. DOI: 10.1016/J.Jalz.2005.06.326  0.301
2004 Volpicelli-Daley LA, Levey A. Immunohistochemical localization of proteins in the nervous system. Current Protocols in Neuroscience / Editorial Board, Jacqueline N. Crawley ... [Et Al.]. Unit 1.2. PMID 18428596 DOI: 10.1002/0471142301.ns0102s25  0.657
2004 Scherzer CR, Offe K, Gearing M, Rees HD, Fang G, Heilman CJ, Schaller C, Bujo H, Levey AI, Lah JJ. Loss of apolipoprotein E receptor LR11 in Alzheimer disease. Archives of Neurology. 61: 1200-5. PMID 15313836 DOI: 10.1001/Archneur.61.8.1200  0.804
2004 Weiner DM, Meltzer HY, Veinbergs I, Donohue EM, Spalding TA, Smith TT, Mohell N, Harvey SC, Lameh J, Nash N, Vanover KE, Olsson R, Jayathilake K, Lee M, Levey AI, et al. The role of M1 muscarinic receptor agonism of N-desmethylclozapine in the unique clinical effects of clozapine. Psychopharmacology. 177: 207-16. PMID 15258717 DOI: 10.1007/S00213-004-1940-5  0.325
2004 Liao L, Cheng D, Wang J, Duong DM, Losik TG, Gearing M, Rees HD, Lah JJ, Levey AI, Peng J. Proteomic characterization of postmortem amyloid plaques isolated by laser capture microdissection. The Journal of Biological Chemistry. 279: 37061-8. PMID 15220353 DOI: 10.1074/Jbc.M403672200  0.426
2004 Weiner DM, Goodman MW, Colpitts TM, Feddock MA, Duggento KL, Nash NR, Levey AI, Brann MR. Functional screening of drug target genes: m1 muscarinic acetylcholine receptor phenotypes in degenerative dementias. American Journal of Pharmacogenomics : Genomics-Related Research in Drug Development and Clinical Practice. 4: 119-28. PMID 15059034 DOI: 10.2165/00129785-200404020-00006  0.332
2004 Bernstein LS, Ramineni S, Hague C, Cladman W, Chidiac P, Levey AI, Hepler JR. RGS2 binds directly and selectively to the M1 muscarinic acetylcholine receptor third intracellular loop to modulate Gq/11alpha signaling. The Journal of Biological Chemistry. 279: 21248-56. PMID 14976183 DOI: 10.1074/Jbc.M312407200  0.318
2004 Tata AM, De Stefano ME, Tomassy GS, Vilaró MT, Levey AI, Biagioni S. Subpopulations of rat dorsal root ganglion neurons express active vesicular acetylcholine transporter. Journal of Neuroscience Research. 75: 194-202. PMID 14705140 DOI: 10.1002/jnr.10855  0.317
2004 Volpicelli LA, Levey AI. Muscarinic acetylcholine receptor subtypes in cerebral cortex and hippocampus. Progress in Brain Research. 145: 59-66. PMID 14650906 DOI: 10.1016/S0079-6123(03)45003-6  0.363
2004 Dodson SE, Offe K, Carter SC, Shoemaker JT, Fang G, Lah JJ, Levey AI. P3-303 Examining the role of the APOE receptor LR11 in the etiopathology of Alzheimer's disease Neurobiology of Aging. 25: S441. DOI: 10.1016/S0197-4580(04)81453-2  0.796
2004 Offe K, Williams TJ, Fang G, Lah JJ, Levey AI. P3-300 Effect of targeted domain deletions on LR11-mediated regulation of extracellular Aβ levels Neurobiology of Aging. 25: S440. DOI: 10.1016/S0197-4580(04)81450-7  0.768
2004 Sager KL, Lah JJ, Levey AI, Rees HD, Mufson EJ, Bennett DA, Wuu J, Leurgans S. P3-295 Quantification of LR11 expression in mild cognitive impairment, a human model for early Alzheimer's disease Neurobiology of Aging. 25. DOI: 10.1016/S0197-4580(04)81445-3  0.333
2004 Jones KA, Carter S, Shoemaker JT, Solomon IG, Lah J, Levey A, Decker MJ. P1-247 Intermitten hypoxic insults occurring during a period of critical brain development reduce the expression of insoluble beta amyloid within the hippocampus Neurobiology of Aging. 25. DOI: 10.1016/S0197-4580(04)80560-8  0.3
2004 Goldstein FC, Ashley AV, Freedman LJ, Cellar J, Harrison J, Lah JJ, Levey AI. P1-023 Functional abilities in patients with mild cognitive impairment versus Alzheimer's disease and normal controls Neurobiology of Aging. 25: S100. DOI: 10.1016/S0197-4580(04)80337-3  0.321
2003 Volpicelli-Daley LA, Hrabovska A, Duysen EG, Ferguson SM, Blakely RD, Lockridge O, Levey AI. Altered striatal function and muscarinic cholinergic receptors in acetylcholinesterase knockout mice. Molecular Pharmacology. 64: 1309-16. PMID 14645660 DOI: 10.1124/Mol.64.6.1309  0.678
2003 Levey AI. Chronically mad as a hatter: anticholinergics and Alzheimer's disease pathology. Annals of Neurology. 54: 144-6. PMID 12891665 DOI: 10.1002/ana.10667  0.351
2003 Hill K, Li Y, Bennett M, McKay M, Zhu X, Shern J, Torre E, Lah JJ, Levey AI, Kahn RA. Munc18 interacting proteins: ADP-ribosylation factor-dependent coat proteins that regulate the traffic of beta-Alzheimer's precursor protein. The Journal of Biological Chemistry. 278: 36032-40. PMID 12842896 DOI: 10.1074/Jbc.M301632200  0.497
2003 Kus L, Borys E, Ping Chu Y, Ferguson SM, Blakely RD, Emborg ME, Kordower JH, Levey AI, Mufson EJ. Distribution of high affinity choline transporter immunoreactivity in the primate central nervous system. The Journal of Comparative Neurology. 463: 341-57. PMID 12820166 DOI: 10.1002/Cne.10759  0.302
2003 Volpicelli-Daley LA, Duysen EG, Lockridge O, Levey AI. Altered hippocampal muscarinic receptors in acetylcholinesterase-deficient mice. Annals of Neurology. 53: 788-96. PMID 12783426 DOI: 10.1002/Ana.10589  0.679
2003 Li B, Duysen EG, Volpicelli-Daley LA, Levey AI, Lockridge O. Regulation of muscarinic acetylcholine receptor function in acetylcholinesterase knockout mice. Pharmacology, Biochemistry, and Behavior. 74: 977-86. PMID 12667913 DOI: 10.1016/S0091-3057(03)00022-4  0.653
2003 Berkeley JL, Levey AI. Cell-specific extracellular signal-regulated kinase activation by multiple G protein-coupled receptor families in hippocampus. Molecular Pharmacology. 63: 128-35. PMID 12488545 DOI: 10.1124/Mol.63.1.128  0.781
2002 Stephans SE, Miller GW, Levey AI, Greenamyre JT. Acute mitochondrial and chronic toxicological effects of 1-methyl-4-phenylpyridinium in human neuroblastoma cells. Neurotoxicology. 23: 569-80. PMID 12428729 DOI: 10.1016/S0161-813X(02)00060-8  0.466
2002 Volpicelli LA, Lah JJ, Fang G, Goldenring JR, Levey AI. Rab11a and myosin Vb regulate recycling of the M4 muscarinic acetylcholine receptor. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 22: 9776-84. PMID 12427833 DOI: 10.1523/Jneurosci.22-22-09776.2002  0.342
2002 Duttaroy A, Gomeza J, Gan JW, Siddiqui N, Basile AS, Harman WD, Smith PL, Felder CC, Levey AI, Wess J. Evaluation of muscarinic agonist-induced analgesia in muscarinic acetylcholine receptor knockout mice. Molecular Pharmacology. 62: 1084-93. PMID 12391271 DOI: 10.1124/Mol.62.5.1084  0.302
2002 Levy OA, Lah JJ, Levey AI. Notch signaling inhibits PC12 cell neurite outgrowth via RBP-J-dependent and -independent mechanisms. Developmental Neuroscience. 24: 79-88. PMID 12145413 DOI: 10.1159/000064948  0.583
2002 Berkeley JL, Decker MJ, Levey AI. The role of muscarinic acetylcholine receptor-mediated activation of extracellular signal-regulated kinase 1/2 in pilocarpine-induced seizures. Journal of Neurochemistry. 82: 192-201. PMID 12091480 DOI: 10.1046/J.1471-4159.2002.00977.X  0.763
2002 McClatchy DB, Knudsen CR, Clark BF, Kahn RA, Hall RA, Levey AI. Novel interaction between the M4 muscarinic acetylcholine receptor and elongation factor 1A2. The Journal of Biological Chemistry. 277: 29268-74. PMID 12048193 DOI: 10.1074/Jbc.M203081200  0.723
2002 Li Y, Chin LS, Levey AI, Li L. Huntingtin-associated protein 1 interacts with hepatocyte growth factor-regulated tyrosine kinase substrate and functions in endosomal trafficking. The Journal of Biological Chemistry. 277: 28212-21. PMID 12021262 DOI: 10.1074/Jbc.M111612200  0.316
2001 Miller GW, Levey AI. Immunochemical analysis of dopamine transporters in Parkinson's disease. Methods in Molecular Medicine. 62: 167-77. PMID 21318775 DOI: 10.1385/1-59259-142-6:167  0.503
2001 Berkeley JL, Gomeza J, Wess J, Hamilton SE, Nathanson NM, Levey AI. M1 muscarinic acetylcholine receptors activate extracellular signal-regulated kinase in CA1 pyramidal neurons in mouse hippocampal slices. Molecular and Cellular Neurosciences. 18: 512-24. PMID 11922142 DOI: 10.1006/Mcne.2001.1042  0.788
2001 Erisir A, Levey AI, Aoki C. Muscarinic receptor M(2) in cat visual cortex: laminar distribution, relationship to gamma-aminobutyric acidergic neurons, and effect of cingulate lesions. The Journal of Comparative Neurology. 441: 168-85. PMID 11745643 DOI: 10.1002/Cne.1405  0.311
2001 Goldstein FC, Ashley AV, Gearing M, Hanfelt J, Penix L, Freedman LJ, Levey AI. Apolipoprotein E and age at onset of Alzheimer's disease in African American patients. Neurology. 57: 1923-5. PMID 11723294 DOI: 10.1212/Wnl.57.10.1923  0.332
2001 Killick R, Pollard CC, Asuni AA, Mudher AK, Richardson JC, Rupniak HT, Sheppard PW, Varndell IM, Brion JP, Levey AI, Levy OA, Vestling M, Cowburn R, Lovestone S, Anderton BH. Presenilin 1 independently regulates beta-catenin stability and transcriptional activity. The Journal of Biological Chemistry. 276: 48554-61. PMID 11606587 DOI: 10.1074/Jbc.M108332200  0.49
2001 Volpicelli LA, Lah JJ, Levey AI. Rab5-dependent trafficking of the m4 muscarinic acetylcholine receptor to the plasma membrane, early endosomes, and multivesicular bodies. The Journal of Biological Chemistry. 276: 47590-8. PMID 11590149 DOI: 10.1074/Jbc.M106535200  0.325
2001 Torres GE, Yao WD, Mohn AR, Quan H, Kim KM, Levey AI, Staudinger J, Caron MG. Functional interaction between monoamine plasma membrane transporters and the synaptic PDZ domain-containing protein PICK1. Neuron. 30: 121-34. PMID 11343649 DOI: 10.1016/S0896-6273(01)00267-7  0.487
2001 Counts SE, Lah JJ, Levey AI. The regulation of presenilin-1 by nerve growth factor. Journal of Neurochemistry. 76: 679-89. PMID 11158238 DOI: 10.1046/J.1471-4159.2001.00014.X  0.608
2000 Levey AI. Immunization for Alzheimer's disease: a shot in the arm or a whiff? Annals of Neurology. 48: 553-5. PMID 11026438 DOI: 10.1002/1531-8249(200010)48:4<553::AID-ANA1>3.0.CO;2-E  0.327
2000 Lah JJ, Levey AI. Endogenous presenilin-1 targets to endocytic rather than biosynthetic compartments. Molecular and Cellular Neurosciences. 16: 111-26. PMID 10924255 DOI: 10.1006/Mcne.2000.0861  0.348
2000 Berkeley JL, Levey AI. Muscarinic activation of mitogen-activated protein kinase in PC12 cells. Journal of Neurochemistry. 75: 487-93. PMID 10899923 DOI: 10.1046/J.1471-4159.2000.0750487.X  0.784
2000 Ciliax BJ, Nash N, Heilman C, Sunahara R, Hartney A, Tiberi M, Rye DB, Caron MG, Niznik HB, Levey AI. Dopamine D(5) receptor immunolocalization in rat and monkey brain. Synapse (New York, N.Y.). 37: 125-45. PMID 10881034 DOI: 10.1002/1098-2396(200008)37:2<125::Aid-Syn7>3.0.Co;2-7  0.474
2000 Rouse ST, Edmunds SM, Yi H, Gilmor ML, Levey AI. Localization of M(2) muscarinic acetylcholine receptor protein in cholinergic and non-cholinergic terminals in rat hippocampus. Neuroscience Letters. 284: 182-6. PMID 10773429 DOI: 10.1016/S0304-3940(00)01011-9  0.337
2000 Levey AI. Molecules of the brain. Hospital Practice (1995). 35: 41-8, 51-4. PMID 10689389 DOI: 10.3810/Hp.2000.02.186  0.335
1999 Green J, Levey AI. Event-related potential changes in groups at increased risk for Alzheimer disease. Archives of Neurology. 56: 1398-403. PMID 10555661 DOI: 10.1001/archneur.56.11.1398  0.341
1999 Kosinski CM, Risso Bradley S, Conn PJ, Levey AI, Landwehrmeyer GB, Penney JB, Young AB, Standaert DG. Localization of metabotropic glutamate receptor 7 mRNA and mGluR7a protein in the rat basal ganglia. The Journal of Comparative Neurology. 415: 266-84. PMID 10545164 DOI: 10.1002/(SICI)1096-9861(19991213)415:2<266::AID-CNE9>3.0.CO;2-7  0.314
1999 Miller GW, Kirby ML, Levey AI, Bloomquist JR. Heptachlor alters expression and function of dopamine transporters. Neurotoxicology. 20: 631-7. PMID 10499361  0.415
1999 Miller GW, Gainetdinov RR, Levey AI, Caron MG. Dopamine transporters and neuronal injury. Trends in Pharmacological Sciences. 20: 424-9. PMID 10498956 DOI: 10.1016/S0165-6147(99)01379-6  0.585
1999 Ren RF, Lah JJ, Diehlmann A, Kim ES, Hawver DB, Levey AI, Beyreuther K, Flanders KC. Differential effects of transforming growth factor-beta(s) and glial cell line-derived neurotrophic factor on gene expression of presenilin-1 in human post-mitotic neurons and astrocytes. Neuroscience. 93: 1041-9. PMID 10473269 DOI: 10.1016/S0306-4522(99)00215-8  0.318
1999 Gilmor ML, Erickson JD, Varoqui H, Hersh LB, Bennett DA, Cochran EJ, Mufson EJ, Levey AI. Preservation of nucleus basalis neurons containing choline acetyltransferase and the vesicular acetylcholine transporter in the elderly with mild cognitive impairment and early Alzheimer's disease. The Journal of Comparative Neurology. 411: 693-704. PMID 10421878 DOI: 10.1002/(Sici)1096-9861(19990906)411:4<693::Aid-Cne13>3.0.Co;2-D  0.388
1999 Ciliax BJ, Drash GW, Staley JK, Haber S, Mobley CJ, Miller GW, Mufson EJ, Mash DC, Levey AI. Immunocytochemical localization of the dopamine transporter in human brain. The Journal of Comparative Neurology. 409: 38-56. PMID 10363710 DOI: 10.1002/(Sici)1096-9861(19990621)409:1<38::Aid-Cne4>3.0.Co;2-1  0.503
1999 Smiley JF, Levey AI, Mesulam MM. m2 muscarinic receptor immunolocalization in cholinergic cells of the monkey basal forebrain and striatum. Neuroscience. 90: 803-14. PMID 10218781 DOI: 10.1016/S0306-4522(98)00527-2  0.336
1999 Mirra SS, Murrell JR, Gearing M, Spillantini MG, Goedert M, Crowther RA, Levey AI, Jones R, Green J, Shoffner JM, Wainer BH, Schmidt ML, Trojanowski JQ, Ghetti B. Tau pathology in a family with dementia and a P301L mutation in tau. Journal of Neuropathology and Experimental Neurology. 58: 335-45. PMID 10218629 DOI: 10.1097/00005072-199904000-00004  0.602
1999 Bradley SR, Standaert DG, Rhodes KJ, Rees HD, Testa CM, Levey AI, Conn PJ. Immunohistochemical localization of subtype 4a metabotropic glutamate receptors in the rat and mouse basal ganglia. The Journal of Comparative Neurology. 407: 33-46. PMID 10213186 DOI: 10.1002/(SICI)1096-9861(19990428)407:1<33::AID-CNE3>3.0.CO;2-G  0.347
1999 Miller GW, Erickson JD, Perez JT, Penland SN, Mash DC, Rye DB, Levey AI. Immunochemical analysis of vesicular monoamine transporter (VMAT2) protein in Parkinson's disease. Experimental Neurology. 156: 138-48. PMID 10192785 DOI: 10.1006/Exnr.1998.7008  0.516
1999 Rouse ST, Marino MJ, Potter LT, Conn PJ, Levey AI. Muscarinic receptor subtypes involved in hippocampal circuits. Life Sciences. 64: 501-9. PMID 10069516 DOI: 10.1016/S0024-3205(98)00594-3  0.322
1999 Plummer KL, Manning KA, Levey AI, Rees HD, Uhlrich DJ. Muscarinic receptor subtypes in the lateral geniculate nucleus: a light and electron microscopic analysis. The Journal of Comparative Neurology. 404: 408-25. PMID 9952356 DOI: 10.1002/(SICI)1096-9861(19990215)404:3<408::AID-CNE9>3.0.CO;2-Y  0.312
1999 Berkeley J, Lah J, Levey A. Muscarinic activation of MAPK in PC12 cells Life Sciences. 64: 566. DOI: 10.1016/S0024-3205(99)90488-5  0.76
1998 Gilmor ML, Counts SE, Wiley RG, Levey AI. Coordinate expression of the vesicular acetylcholine transporter and choline acetyltransferase following septohippocampal pathway lesions. Journal of Neurochemistry. 71: 2411-20. PMID 9832139 DOI: 10.1046/J.1471-4159.1998.71062411.X  0.596
1998 Miller GW, Gilmor ML, Levey AI. Generation of transporter-specific antibodies. Methods in Enzymology. 296: 407-22. PMID 9779463 DOI: 10.1016/S0076-6879(98)96029-3  0.469
1998 Marino MJ, Rouse ST, Levey AI, Potter LT, Conn PJ. Activation of the genetically defined m1 muscarinic receptor potentiates N-methyl-D-aspartate (NMDA) receptor currents in hippocampal pyramidal cells. Proceedings of the National Academy of Sciences of the United States of America. 95: 11465-70. PMID 9736760 DOI: 10.1073/Pnas.95.19.11465  0.336
1998 Rouse ST, Gilmor ML, Levey AI. Differential presynaptic and postsynaptic expression of m1-m4 muscarinic acetylcholine receptors at the perforant pathway/granule cell synapse. Neuroscience. 86: 221-32. PMID 9692756 DOI: 10.1016/S0306-4522(97)00681-7  0.31
1998 Bradley SR, Rees HD, Yi H, Levey AI, Conn PJ. Distribution and developmental regulation of metabotropic glutamate receptor 7a in rat brain. Journal of Neurochemistry. 71: 636-45. PMID 9681454 DOI: 10.1046/J.1471-4159.1998.71020636.X  0.306
1998 Glass JD, Nash N, Dry I, Culver D, Levey AI, Wesselingh S. Cloning of m-calpain 80 kD subunit from the axonal degeneration-resistant WLD(S) mouse mutant. Journal of Neuroscience Research. 52: 653-60. PMID 9669314 DOI: 10.1002/(SICI)1097-4547(19980615)52:6<653::AID-JNR4>3.0.CO;2-7  0.305
1998 Smiley JF, Levey AI, Mesulam MM. Infracortical interstitial cells concurrently expressing m2-muscarinic receptors, acetylcholinesterase and nicotinamide adenine dinucleotide phosphate-diaphorase in the human and monkey cerebral cortex. Neuroscience. 84: 755-69. PMID 9579781 DOI: 10.1016/S0306-4522(97)00524-1  0.347
1998 Gainetdinov RR, Fumagalli F, Wang YM, Jones SR, Levey AI, Miller GW, Caron MG. Increased MPTP neurotoxicity in vesicular monoamine transporter 2 heterozygote knockout mice. Journal of Neurochemistry. 70: 1973-8. PMID 9572281 DOI: 10.1046/J.1471-4159.1998.70051973.X  0.575
1998 Hájos N, Papp EC, Acsády L, Levey AI, Freund TF. Distinct interneuron types express m2 muscarinic receptor immunoreactivity on their dendrites or axon terminals in the hippocampus. Neuroscience. 82: 355-76. PMID 9466448 DOI: 10.1016/S0306-4522(97)00300-X  0.306
1998 Mrzljak L, Levey AI, Belcher S, Goldman-Rakic PS. Localization of the m2 muscarinic acetylcholine receptor protein and mRNA in cortical neurons of the normal and cholinergically deafferented rhesus monkey. The Journal of Comparative Neurology. 390: 112-32. PMID 9456180 DOI: 10.1002/(Sici)1096-9861(19980105)390:1<112::Aid-Cne10>3.0.Co;2-Z  0.352
1997 Gearing M, Levey AI, Mirra SS. Diffuse plaques in the striatum in Alzheimer disease (AD): relationship to the striatal mosaic and selected neuropeptide markers. Journal of Neuropathology and Experimental Neurology. 56: 1363-70. PMID 9413285 DOI: 10.1097/00005072-199712000-00011  0.367
1997 Ince E, Ciliax BJ, Levey AI. Differential expression of D1 and D2 dopamine and m4 muscarinic acetylcholine receptor proteins in identified striatonigral neurons. Synapse (New York, N.Y.). 27: 357-66. PMID 9372558 DOI: 10.1002/(SICI)1098-2396(199712)27:4<357::AID-SYN9>3.0.CO;2-B  0.323
1997 Hamilton SE, Loose MD, Qi M, Levey AI, Hille B, McKnight GS, Idzerda RL, Nathanson NM. Disruption of the m1 receptor gene ablates muscarinic receptor-dependent M current regulation and seizure activity in mice. Proceedings of the National Academy of Sciences of the United States of America. 94: 13311-6. PMID 9371842 DOI: 10.1073/Pnas.94.24.13311  0.332
1997 Subramanian T, Emerich DF, Bakay RA, Hoffman JM, Goodman MM, Shoup TM, Miller GW, Levey AI, Hubert GW, Batchelor S, Winn SR, Saydoff JA, Watts RL. Polymer-encapsulated PC-12 cells demonstrate high-affinity uptake of dopamine in vitro and 18F-Dopa uptake and metabolism after intracerebral implantation in nonhuman primates. Cell Transplantation. 6: 469-77. PMID 9331498 DOI: 10.1016/S0963-6897(97)00049-3  0.458
1997 Nash NR, Heilman CJ, Rees HD, Levey AI. Cloning and localization of exon 5-containing isoforms of the NMDAR1 subunit in human and rat brains. Journal of Neurochemistry. 69: 485-93. PMID 9231706 DOI: 10.1046/J.1471-4159.1997.69020485.X  0.307
1997 Levey AI, Heilman CJ, Lah JJ, Nash NR, Rees HD, Wakai M, Mirra SS, Rye DB, Nochlin D, Bird TD, Mufson EJ. Presenilin-1 protein expression in familial and sporadic Alzheimer's disease. Annals of Neurology. 41: 742-53. PMID 9189035 DOI: 10.1002/Ana.410410610  0.393
1997 Miller GW, Staley JK, Heilman CJ, Perez JT, Mash DC, Rye DB, Levey AI. Immunochemical analysis of dopamine transporter protein in Parkinson's disease. Annals of Neurology. 41: 530-9. PMID 9124811 DOI: 10.1002/Ana.410410417  0.509
1997 Rouse ST, Thomas TM, Levey AI. Muscarinic acetylcholine receptor subtype, m2: diverse functional implications of differential synaptic localization. Life Sciences. 60: 1031-8. PMID 9121344 DOI: 10.1016/S0024-3205(97)00044-1  0.349
1997 Bodick NC, Offen WW, Levey AI, Cutler NR, Gauthier SG, Satlin A, Shannon HE, Tollefson GD, Rasmussen K, Bymaster FP, Hurley DJ, Potter WZ, Paul SM. Effects of xanomeline, a selective muscarinic receptor agonist, on cognitive function and behavioral symptoms in Alzheimer disease. Archives of Neurology. 54: 465-73. PMID 9109749 DOI: 10.1001/Archneur.1997.00550160091022  0.336
1997 Staley JK, Talbot JZ, Ciliax BJ, Miller GW, Levey AI, Kung MP, Kung HF, Mash DC. Radioligand binding and immunoautoradiographic evidence for a lack of toxicity to dopaminergic nerve terminals in human cocaine overdose victims. Brain Research. 747: 219-29. PMID 9045996 DOI: 10.1016/S0006-8993(96)01196-1  0.473
1997 Lah JJ, Heilman CJ, Nash NR, Rees HD, Yi H, Counts SE, Levey AI. Light and electron microscopic localization of presenilin-1 in primate brain. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 17: 1971-80. PMID 9045726 DOI: 10.1523/Jneurosci.17-06-01971.1997  0.64
1997 Subramanian T, Emerich DF, Bakay RAE, Hoffman JM, Goodman MM, Shoup TM, Miller GW, Levey AI, Hubert GW, Batchelor S, Winn SR, Saydoff JA, Watts RL. Polymer-Encapsulated PC-12 Cells Demonstrate High-Affinity Uptake of Dopamine in Vitro and18F-DOPA Uptake and Metabolism after Intracerebral Implantation in Nonhuman Primates Cell Transplantation. 6: 469-477. DOI: 10.1177/096368979700600506  0.37
1996 Levey AI. Muscarinic acetylcholine receptor expression in memory circuits: implications for treatment of Alzheimer disease. Proceedings of the National Academy of Sciences of the United States of America. 93: 13541-6. PMID 8942969 DOI: 10.1073/Pnas.93.24.13541  0.411
1996 Borchelt DR, Thinakaran G, Eckman CB, Lee MK, Davenport F, Ratovitsky T, Prada CM, Kim G, Seekins S, Yager D, Slunt HH, Wang R, Seeger M, Levey AI, Gandy SE, et al. Familial Alzheimer's disease-linked presenilin 1 variants elevate Abeta1-42/1-40 ratio in vitro and in vivo. Neuron. 17: 1005-13. PMID 8938131 DOI: 10.1016/S0896-6273(00)80230-5  0.358
1996 Yao W, Godfrey DA, Levey AI. Immunolocalization of muscarinic acetylcholine subtype 2 receptors in rat cochlear nucleus. The Journal of Comparative Neurology. 373: 27-40. PMID 8876460 DOI: 10.1002/(Sici)1096-9861(19960909)373:1<27::Aid-Cne3>3.0.Co;2-F  0.316
1996 Thinakaran G, Borchelt DR, Lee MK, Slunt HH, Spitzer L, Kim G, Ratovitsky T, Davenport F, Nordstedt C, Seeger M, Hardy J, Levey AI, Gandy SE, Jenkins NA, Copeland NG, et al. Endoproteolysis of presenilin 1 and accumulation of processed derivatives in vivo. Neuron. 17: 181-90. PMID 8755489 DOI: 10.1016/S0896-6273(00)80291-3  0.328
1996 Yung KK, Smith AD, Levey AI, Bolam JP. Synaptic connections between spiny neurons of the direct and indirect pathways in the neostriatum of the rat: evidence from dopamine receptor and neuropeptide immunostaining. The European Journal of Neuroscience. 8: 861-9. PMID 8743734 DOI: 10.1111/j.1460-9568.1996.tb01573.x  0.314
1996 Bradley SR, Levey AI, Hersch SM, Conn PJ. Immunocytochemical localization of group III metabotropic glutamate receptors in the hippocampus with subtype-specific antibodies. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 16: 2044-56. PMID 8604049 DOI: 10.1523/Jneurosci.16-06-02044.1996  0.318
1996 Gilmor ML, Nash NR, Roghani A, Edwards RH, Yi H, Hersch SM, Levey AI. Expression of the putative vesicular acetylcholine transporter in rat brain and localization in cholinergic synaptic vesicles. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 16: 2179-90. PMID 8601799 DOI: 10.1523/Jneurosci.16-07-02179.1996  0.35
1995 Flynn DD, Ferrari-DiLeo G, Levey AI, Mash DC. Differential alterations in muscarinic receptor subtypes in Alzheimer's disease: implications for cholinergic-based therapies. Life Sciences. 56: 869-76. PMID 10188787 DOI: 10.1016/0024-3205(95)00022-X  0.392
1995 Jaarsma D, Levey AI, Frostholm A, Rotter A, Voogd J. Light-microscopic distribution and parasagittal organisation of muscarinic receptors in rabbit cerebellar cortex. Journal of Chemical Neuroanatomy. 9: 241-59. PMID 8719274 DOI: 10.1016/0891-0618(95)00089-5  0.31
1995 Flynn DD, Ferrari-DiLeo G, Mash DC, Levey AI. Differential regulation of molecular subtypes of muscarinic receptors in Alzheimer's disease. Journal of Neurochemistry. 64: 1888-91. PMID 7891119 DOI: 10.1046/J.1471-4159.1995.64041888.X  0.386
1995 Qian Y, Melikian HE, Rye DB, Levey AI, Blakely RD. Identification and characterization of antidepressant-sensitive serotonin transporter proteins using site-specific antibodies. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 15: 1261-74. PMID 7869097 DOI: 10.1523/Jneurosci.15-02-01261.1995  0.309
1995 Levey AI, Edmunds SM, Koliatsos V, Wiley RG, Heilman CJ. Expression of m1-m4 muscarinic acetylcholine receptor proteins in rat hippocampus and regulation by cholinergic innervation. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 15: 4077-92. PMID 7751967 DOI: 10.1523/Jneurosci.15-05-04077.1995  0.333
1995 Gutekunst CA, Levey AI, Heilman CJ, Whaley WL, Yi H, Nash NR, Rees HD, Madden JJ, Hersch SM. Identification and localization of huntingtin in brain and human lymphoblastoid cell lines with anti-fusion protein antibodies. Proceedings of the National Academy of Sciences of the United States of America. 92: 8710-4. PMID 7568002 DOI: 10.1073/Pnas.92.19.8710  0.362
1995 Hohmann CF, Potter ED, Levey AI. Development of muscarinic receptor subtypes in the forebrain of the mouse. The Journal of Comparative Neurology. 358: 88-101. PMID 7560279 DOI: 10.1002/cne.903580106  0.328
1995 Ciliax BJ, Heilman C, Demchyshyn LL, Pristupa ZB, Ince E, Hersch SM, Niznik HB, Levey AI. The dopamine transporter: immunochemical characterization and localization in brain. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 15: 1714-23. PMID 7534339 DOI: 10.1523/Jneurosci.15-03-01714.1995  0.317
1995 Ciliax BJ, Heilman C, Edmunds S, Hersch SM, Levey AI. [20] Anti-fusion protein antibodies specific for receptor subtypes Methods in Neurosciences. 25: 431-454. DOI: 10.1016/S1043-9471(05)80050-3  0.303
1994 Rothstein JD, Martin L, Levey AI, Dykes-Hoberg M, Jin L, Wu D, Nash N, Kuncl RW. Localization of neuronal and glial glutamate transporters. Neuron. 13: 713-25. PMID 7917301 DOI: 10.1016/0896-6273(94)90038-8  0.323
1994 Levey AI, Edmunds SM, Heilman CJ, Desmond TJ, Frey KA. Localization of muscarinic m3 receptor protein and M3 receptor binding in rat brain. Neuroscience. 63: 207-21. PMID 7898649 DOI: 10.1016/0306-4522(94)90017-5  0.341
1993 Levey AI. Immunological localization of m1-m5 muscarinic acetylcholine receptors in peripheral tissues and brain. Life Sciences. 52: 441-8. PMID 8441326 DOI: 10.1016/0024-3205(93)90300-R  0.32
1993 Mrzljak L, Levey AI, Goldman-Rakic PS. Association of m1 and m2 muscarinic receptor proteins with asymmetric synapses in the primate cerebral cortex: morphological evidence for cholinergic modulation of excitatory neurotransmission. Proceedings of the National Academy of Sciences of the United States of America. 90: 5194-8. PMID 8389473 DOI: 10.1073/pnas.90.11.5194  0.314
1993 Martin LJ, Blackstone CD, Levey AI, Huganir RL, Price DL. AMPA glutamate receptor subunits are differentially distributed in rat brain. Neuroscience. 53: 327-58. PMID 8388083 DOI: 10.1016/0306-4522(93)90199-P  0.327
1993 Martin LJ, Blackstone CD, Levey AI, Huganir RL, Price DL. Cellular localizations of AMPA glutamate receptors within the basal forebrain magnocellular complex of rat and monkey. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 13: 2249-63. PMID 8386757 DOI: 10.1523/Jneurosci.13-05-02249.1993  0.314
1992 Blackstone CD, Moss SJ, Martin LJ, Levey AI, Price DL, Huganir RL. Biochemical characterization and localization of a non-N-methyl-D-aspartate glutamate receptor in rat brain. Journal of Neurochemistry. 58: 1118-26. PMID 1371146 DOI: 10.1111/J.1471-4159.1992.Tb09370.X  0.317
1992 Blackstone CD, Levey AI, Martin LJ, Price DL, Huganir RL. Immunological detection of glutamate receptor subtypes in human central nervous system. Annals of Neurology. 31: 680-3. PMID 1325139 DOI: 10.1002/Ana.410310620  0.335
1991 Levey AI, Kitt CA, Simonds WF, Price DL, Brann MR. Identification and localization of muscarinic acetylcholine receptor proteins in brain with subtype-specific antibodies. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 11: 3218-26. PMID 1941081 DOI: 10.1523/Jneurosci.11-10-03218.1991  0.369
1990 Levey AI, Stormann TM, Brann MR. Bacterial expression of human muscarinic receptor fusion proteins and generation of subtype-specific antisera. Febs Letters. 275: 65-9. PMID 2262002 DOI: 10.1016/0014-5793(90)81440-Y  0.325
1988 Maley BE, Frick ML, Levey AI, Wainer BH, Elde RP. Immunohistochemistry of choline acetyltransferase in the guinea pig brain. Neuroscience Letters. 84: 137-42. PMID 3340318 DOI: 10.1016/0304-3940(88)90397-7  0.585
1988 Lee HJ, Rye DB, Hallanger AE, Levey AI, Wainer BH. Cholinergic vs. noncholinergic efferents from the mesopontine tegmentum to the extrapyramidal motor system nuclei. The Journal of Comparative Neurology. 275: 469-92. PMID 2461392 DOI: 10.1002/cne.902750402  0.566
1987 Levey AI, Hallanger AE, Wainer BH. Choline acetyltransferase immunoreactivity in the rat thalamus. The Journal of Comparative Neurology. 257: 317-32. PMID 3549798 DOI: 10.1002/cne.902570302  0.569
1987 Hallanger AE, Levey AI, Lee HJ, Rye DB, Wainer BH. The origins of cholinergic and other subcortical afferents to the thalamus in the rat. The Journal of Comparative Neurology. 262: 105-24. PMID 2442206 DOI: 10.1002/cne.902620109  0.565
1987 Levey AI, Hallanger AE, Wainer BH. Cholinergic nucleus basalis neurons may influence the cortex via the thalamus. Neuroscience Letters. 74: 7-13. PMID 2436108 DOI: 10.1016/0304-3940(87)90042-5  0.573
1986 Bolam JP, Ingham CA, Izzo PN, Levey AI, Rye DB, Smith AD, Wainer BH. Substance P-containing terminals in synaptic contact with cholinergic neurons in the neostriatum and basal forebrain: a double immunocytochemical study in the rat. Brain Research. 397: 279-89. PMID 2432992 DOI: 10.1016/0006-8993(86)90629-3  0.581
1986 Levey AI, Bolam JP, Rye DB, Hallanger AE, Demuth RM, Mesulam MM, Wainer BH. A light and electron microscopic procedure for sequential double antigen localization using diaminobenzidine and benzidine dihydrochloride. The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society. 34: 1449-57. PMID 2430010 DOI: 10.1177/34.11.2430010  0.551
1985 Wainer BH, Levey AI, Rye DB, Mesulam MM, Mufson EJ. Cholinergic and non-cholinergic septohippocampal pathways. Neuroscience Letters. 54: 45-52. PMID 3974944 DOI: 10.1016/S0304-3940(85)80116-6  0.594
1984 Wainer BH, Levey AI, Mufson EJ, Mesulam MM. Cholinergic systems in mammalian brain identified with antibodies against choline acetyltransferase. Neurochemistry International. 6: 163-82. PMID 20488034 DOI: 10.1016/0197-0186(84)90089-5  0.577
1984 Levey AI, Wainer BH, Rye DB, Mufson EJ, Mesulam MM. Choline acetyltransferase-immunoreactive neurons intrinsic to rodent cortex and distinction from acetylcholinesterase-positive neurons. Neuroscience. 13: 341-53. PMID 6514183 DOI: 10.1016/0306-4522(84)90234-3  0.59
1984 Mufson EJ, Desan PH, Mesulam MM, Wainer BH, Levey AI. Choline acetyltransferase-like immunoreactivity in the forebrain of the red-eared pond turtle (Pseudemys scripta elegans). Brain Research. 323: 103-8. PMID 6395936 DOI: 10.1016/0006-8993(84)90269-5  0.585
1984 Mesulam MM, Mufson EJ, Levey AI, Wainer BH. Atlas of cholinergic neurons in the forebrain and upper brainstem of the macaque based on monoclonal choline acetyltransferase immunohistochemistry and acetylcholinesterase histochemistry. Neuroscience. 12: 669-86. PMID 6382047 DOI: 10.1016/0306-4522(84)90163-5  0.546
1983 Mesulam MM, Mufson EJ, Levey AI, Wainer BH. Cholinergic innervation of cortex by the basal forebrain: cytochemistry and cortical connections of the septal area, diagonal band nuclei, nucleus basalis (substantia innominata), and hypothalamus in the rhesus monkey. The Journal of Comparative Neurology. 214: 170-97. PMID 6841683 DOI: 10.1002/Cne.902140206  0.567
1983 Levey AI, Armstrong DM, Atweh SF, Terry RD, Wainer BH. Monoclonal antibodies to choline acetyltransferase: production, specificity, and immunohistochemistry. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 3: 1-9. PMID 6822847 DOI: 10.1523/Jneurosci.03-01-00001.1983  0.585
1983 Levey AI, Wainer BH, Mufson EJ, Mesulam MM. Co-localization of acetylcholinesterase and choline acetyltransferase in the rat cerebrum. Neuroscience. 9: 9-22. PMID 6348584 DOI: 10.1016/0306-4522(83)90042-8  0.596
1983 Armstrong DM, Saper CB, Levey AI, Wainer BH, Terry RD. Distribution of cholinergic neurons in rat brain: demonstrated by the immunocytochemical localization of choline acetyltransferase. The Journal of Comparative Neurology. 216: 53-68. PMID 6345598 DOI: 10.1002/cne.902160106  0.585
1983 Mesulam MM, Mufson EJ, Wainer BH, Levey AI. Central cholinergic pathways in the rat: an overview based on an alternative nomenclature (Ch1-Ch6). Neuroscience. 10: 1185-201. PMID 6320048 DOI: 10.1016/0306-4522(83)90108-2  0.522
1982 Levey AI, Rye DB, Wainer BH. Immunochemical studies of bovine and human choline-O-acetyltransferase using monoclonal antibodies. Journal of Neurochemistry. 39: 1652-9. PMID 7142993 DOI: 10.1111/J.1471-4159.1982.Tb07999.X  0.546
1982 Levey AI, Wainer BH. Cross-species and intraspecies reactivities of monoclonal antibodies against choline acetyltransferase. Brain Research. 234: 469-73. PMID 7059840 DOI: 10.1016/0006-8993(82)90889-7  0.516
1981 Levey AI, Aoki M, Fitch FW, Wainer BH. The production of monoclonal antibodies reactive with bovine choline acetyltransferase. Brain Research. 218: 383-7. PMID 7272744 DOI: 10.1016/0006-8993(81)91316-0  0.538
Low-probability matches (unlikely to be authored by this person)
2007 Rosen AR, Steenland NK, Hanfelt J, Factor SA, Lah JJ, Levey AI. Evidence of shared risk for Alzheimer's disease and Parkinson's disease using family history. Neurogenetics. 8: 263-70. PMID 17805588 DOI: 10.1007/S10048-007-0100-6  0.299
2006 Khoogar L, Dodson SE, Shoemaker JT, Rees HD, Mufson E, Levey AI, Lah JJ. P4-143: Identification of the apoe receptor sorLA/LR11 as a novel component of hallmark Alzheimer’s disease-related lesions in down syndrome Alzheimers & Dementia. 2. DOI: 10.1016/J.Jalz.2006.05.1882  0.298
2019 Haque RU, Manzanares CM, Brown LN, Pongos AL, Lah JJ, Clifford GD, Levey AI. VisMET: a passive, efficient, and sensitive assessment of visuospatial memory in healthy aging, mild cognitive impairment, and Alzheimer's disease. Learning & Memory (Cold Spring Harbor, N.Y.). 26: 93-100. PMID 30770466 DOI: 10.1101/Lm.048124.118  0.296
1995 Yung KK, Bolam JP, Smith AD, Hersch SM, Ciliax BJ, Levey AI. Immunocytochemical localization of D1 and D2 dopamine receptors in the basal ganglia of the rat: light and electron microscopy. Neuroscience. 65: 709-30. PMID 7609871 DOI: 10.1016/0306-4522(94)00536-E  0.296
2021 Wang X, Allen M, İş Ö, Reddy JS, Tutor-New FQ, Castanedes Casey M, Carrasquillo MM, Oatman SR, Min Y, Asmann YW, Funk C, Nguyen T, Ho CC, Malphrus KG, Seyfried NT, ... Levey AI, et al. Alzheimer's disease and progressive supranuclear palsy share similar transcriptomic changes in distinct brain regions. The Journal of Clinical Investigation. PMID 34813500 DOI: 10.1172/JCI149904  0.296
2009 Zhu GD, Salazar G, Zlatic SA, Fiza B, Doucette MM, Heilman CJ, Levey AI, Faundez V, L'hernault SW. SPE-39 family proteins interact with the HOPS complex and function in lysosomal delivery. Molecular Biology of the Cell. 20: 1223-40. PMID 19109425 DOI: 10.1091/Mbc.E08-07-0728  0.296
1997 Rouse ST, Levey AI. Muscarinic acetylcholine receptor immunoreactivity after hippocampal commissural/associational pathway lesions: evidence for multiple presynaptic receptor subtypes. The Journal of Comparative Neurology. 380: 382-94. PMID 9087520 DOI: 10.1002/(SICI)1096-9861(19970414)380:3<382::AID-CNE7>3.0.CO;2-Z  0.295
2006 Lee TV, Allison KS, Ojelade SA, Giagtzoglou N, Lah JJ, Levey AI, Seyfried NT, Shulman JM. O4-01-05: FUNCTIONAL GENETIC DISSECTION OF AN ALZHEIMER'S DISEASE SUSCEPTIBILITY NETWORK Alzheimer's & Dementia. 14: P1401-P1401. DOI: 10.1016/J.Jalz.2018.06.2913  0.295
1998 Smiley JF, Levey AI, Mesulam MM. Erratum: Infracortical interstitial cells concurrently expressing m2- muscarinic receptors, acetylcholinesterase and nicotinamide adenine dinucleotide phosphate-diaphorase in the human and monkey cerebral cortex (Neuroscience (1998) 84 (755-769)) Neuroscience. 87: 317-318. DOI: 10.1016/S0306-4522(98)00335-2  0.294
2016 Seyfried NT, Ping L, Dammer EB, Duong DM, Gearing M, Deng Q, Lah JJ, Levey AI. O5-06-02: Proteomic Network Analysis to Find Common Mechanisms Underlying Alzheimer's Disease and PD Alzheimer's & Dementia. 12: P390-P391. DOI: 10.1016/J.Jalz.2016.06.736  0.294
2013 Pranski E, Van Sanford CD, Dalal N, Orr AL, Karmali D, Cooper DS, Gearing M, Lah JJ, Levey AI, Betarbet R. NF-κB activity is inversely correlated to RNF11 expression in Parkinson's disease. Neuroscience Letters. 547: 16-20. PMID 23669642 DOI: 10.1016/J.Neulet.2013.04.056  0.293
2022 Johnson ECB, Carter EK, Dammer EB, Duong DM, Gerasimov ES, Liu Y, Liu J, Betarbet R, Ping L, Yin L, Serrano GE, Beach TG, Peng J, De Jager PL, Haroutunian V, ... ... Levey AI, et al. Large-scale deep multi-layer analysis of Alzheimer's disease brain reveals strong proteomic disease-related changes not observed at the RNA level. Nature Neuroscience. 25: 213-225. PMID 35115731 DOI: 10.1038/s41593-021-00999-y  0.293
2009 Jang SW, Liu X, Fu H, Rees H, Yepes M, Levey A, Ye K. Interaction of Akt-phosphorylated SRPK2 with 14-3-3 mediates cell cycle and cell death in neurons. The Journal of Biological Chemistry. 284: 24512-25. PMID 19592491 DOI: 10.1074/Jbc.M109.026237  0.293
2010 Sollinger AB, Goldstein FC, Lah JJ, Levey AI, Factor SA. Mild cognitive impairment in Parkinson's disease: subtypes and motor characteristics. Parkinsonism & Related Disorders. 16: 177-80. PMID 19939721 DOI: 10.1016/J.Parkreldis.2009.11.002  0.292
1996 Mrzljak L, Levey AI, Rakic P. Selective expression of m2 muscarinic receptor in the parvocellular channel of the primate visual cortex. Proceedings of the National Academy of Sciences of the United States of America. 93: 7337-40. PMID 8692994 DOI: 10.1073/Pnas.93.14.7337  0.292
2019 Zhou M, Duong DM, Johnson ECB, Dai J, Lah JJ, Levey AI, Seyfried NT. Mass spectrometry-based quantification of Tau in human cerebrospinal fluid using a complementary tryptic peptide standard. Journal of Proteome Research. PMID 30983353 DOI: 10.1021/Acs.Jproteome.8B00920  0.292
2004 Zola S, Levey A, Lah J, Ouslander J. P1-075 Behavioral tasks and eye-tracking technology for early diagnosis of Alzheimer's disease in patients with mild cognitive impairment (MCI) Neurobiology of Aging. 25: S116. DOI: 10.1016/S0197-4580(04)80389-0  0.292
2011 Hanfelt JJ, Wuu J, Sollinger AB, Greenaway MC, Lah JJ, Levey AI, Goldstein FC. An exploration of subgroups of mild cognitive impairment based on cognitive, neuropsychiatric and functional features: analysis of data from the National Alzheimer's Coordinating Center. The American Journal of Geriatric Psychiatry : Official Journal of the American Association For Geriatric Psychiatry. 19: 940-50. PMID 22024618 DOI: 10.1097/Jgp.0B013E31820Ee9D2  0.291
2011 Szulwach KE, Li X, Li Y, Song CX, Wu H, Dai Q, Irier H, Upadhyay AK, Gearing M, Levey AI, Vasanthakumar A, Godley LA, Chang Q, Cheng X, He C, et al. 5-hmC-mediated epigenetic dynamics during postnatal neurodevelopment and aging. Nature Neuroscience. 14: 1607-16. PMID 22037496 DOI: 10.1038/Nn.2959  0.29
2001 Smith Y, Charara A, Paquet M, Kieval JZ, Paré JF, Hanson JE, Hubert GW, Kuwajima M, Levey AI. Ionotropic and metabotropic GABA and glutamate receptors in primate basal ganglia. Journal of Chemical Neuroanatomy. 22: 13-42. PMID 11470552 DOI: 10.1016/S0891-0618(01)00098-9  0.29
2019 Hsieh YC, Guo C, Yalamanchili HK, Abreha M, Al-Ouran R, Li Y, Dammer EB, Lah JJ, Levey AI, Bennett DA, De Jager PL, Seyfried NT, Liu Z, Shulman JM. Tau-Mediated Disruption of the Spliceosome Triggers Cryptic RNA Splicing and Neurodegeneration in Alzheimer's Disease. Cell Reports. 29: 301-316.e10. PMID 31597093 DOI: 10.1016/J.Celrep.2019.08.104  0.29
2017 Wingo TS, Duong DM, Zhou M, Dammer EB, Wu H, Cutler DJ, Lah JJ, Levey AI, Seyfried NT. Integrating Next-Generation Genomic Sequencing and Mass Spectrometry to Estimate Allele-Specific Protein Abundance in Human Brain. Journal of Proteome Research. PMID 28691493 DOI: 10.1021/Acs.Jproteome.7B00324  0.29
1994 Smiley JF, Levey AI, Ciliax BJ, Goldman-Rakic PS. D1 dopamine receptor immunoreactivity in human and monkey cerebral cortex: predominant and extrasynaptic localization in dendritic spines. Proceedings of the National Academy of Sciences of the United States of America. 91: 5720-4. PMID 7911245 DOI: 10.1073/pnas.91.12.5720  0.29
2008 Steenland NK, Auman CM, Patel PM, Bartell SM, Goldstein FC, Levey AI, Lah JJ. Development of a rapid screening instrument for mild cognitive impairment and undiagnosed dementia. Journal of Alzheimer's Disease : Jad. 15: 419-27. PMID 18997295 DOI: 10.3233/Jad-2008-15308  0.289
2006 Bishof IJ, Dammer EB, Duong D, Gearing M, Lah JJ, Levey AI, Seyfried NT. O2-02-05: RNA-BINDING PROTEINS WITH MIXED CHARGE DOMAINS SELF-ASSEMBLE AND AGGREGATE IN ALZHEIMER'S DISEASE Alzheimer's & Dementia. 14: P612-P612. DOI: 10.1016/J.Jalz.2018.06.2649  0.289
2000 Aizman O, Brismar H, Uhlén P, Zettergren E, Levey AI, Forssberg H, Greengard P, Aperia A. Anatomical and physiological evidence for D1 and D2 dopamine receptor colocalization in neostriatal neurons. Nature Neuroscience. 3: 226-30. PMID 10700253 DOI: 10.1038/72929  0.289
2001 Freeman A, Ciliax B, Bakay R, Daley J, Miller RD, Keating G, Levey A, Rye D. Nigrostriatal collaterals to thalamus degenerate in parkinsonian animal models. Annals of Neurology. 50: 321-329. PMID 11558788 DOI: 10.1002/Ana.1119  0.289
1996 Wilson JM, Levey AI, Rajput A, Ang L, Guttman M, Shannak K, Niznik HB, Hornykiewicz O, Pifl C, Kish SJ. Differential changes in neurochemical markers of striatal dopamine nerve terminals in idiopathic Parkinson's disease. Neurology. 47: 718-26. PMID 8797470 DOI: 10.1212/Wnl.47.3.718  0.288
2006 Crimmins S, Jin Y, Wheeler C, Huffman AK, Chapman C, Dobrunz LE, Levey A, Roth KA, Wilson JA, Wilson SM. Transgenic rescue of ataxia mice with neuronal-specific expression of ubiquitin-specific protease 14. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 26: 11423-31. PMID 17079671 DOI: 10.1523/Jneurosci.3600-06.2006  0.288
1993 Levey AI, Hersch SM, Rye DB, Sunahara RK, Niznik HB, Kitt CA, Price DL, Maggio R, Brann MR, Ciliax BJ. Localization of D1 and D2 dopamine receptors in brain with subtype-specific antibodies. Proceedings of the National Academy of Sciences of the United States of America. 90: 8861-5. PMID 8415621 DOI: 10.1073/Pnas.90.19.8861  0.288
1998 Bernard V, Laribi O, Levey AI, Bloch B. Stimulation of muscarinic receptors in vivo induces dramatic modifications of the subcellular distribution of the m2 muscarinic receptor in striatal interneurons Journal of Physiology-Paris. 92: 407-408. DOI: 10.1016/S0928-4257(99)80020-5  0.288
2004 Bliwise DL, Wood-Siverio C, Saunders DD, Greer SG, Hitchcock SE, Cellar J, Levey AI. P2-246 APOE4 genotype and sleep apnea in Alzheimer's disease: initial studies Neurobiology of Aging. 25. DOI: 10.1016/S0197-4580(04)80992-8  0.286
2007 Beekly DL, Ramos EM, Lee WW, Deitrich WD, Jacka ME, Wu J, Hubbard JL, Koepsell TD, Morris JC, Kukull WA, Reiman EM, Kowall N, Landreth G, Shelanski M, Welsh-Bohmer K, ... Levey AI, et al. The National Alzheimer's Coordinating Center (NACC) database: The uniform data set Alzheimer Disease and Associated Disorders. 21: 249-258. PMID 17804958 DOI: 10.1097/Wad.0B013E318142774E  0.285
2019 Wingo AP, Dammer EB, Breen MS, Logsdon BA, Duong DM, Troncosco JC, Thambisetty M, Beach TG, Serrano GE, Reiman EM, Caselli RJ, Lah JJ, Seyfried NT, Levey AI, Wingo TS. Large-scale proteomic analysis of human brain identifies proteins associated with cognitive trajectory in advanced age. Nature Communications. 10: 1619. PMID 30962425 DOI: 10.1038/S41467-019-09613-Z  0.285
2002 Mufson EJ, Ma SY, Dills J, Cochran EJ, Leurgans S, Wuu J, Bennett DA, Jaffar S, Gilmor ML, Levey AI, Kordower JH. Loss of basal forebrain P75(NTR) immunoreactivity in subjects with mild cognitive impairment and Alzheimer's disease. The Journal of Comparative Neurology. 443: 136-53. PMID 11793352 DOI: 10.1002/Cne.10122  0.284
2012 Pranski EL, Van Sanford CD, Dalal NV, Orr AL, Karmali D, Cooper DS, Costa N, Heilman CJ, Gearing M, Lah JJ, Levey AI, Betarbet RS. Comparative distribution of protein components of the A20 ubiquitin-editing complex in normal human brain. Neuroscience Letters. 520: 104-9. PMID 22634524 DOI: 10.1016/J.Neulet.2012.05.043  0.284
1998 Sesack SR, Hawrylak VA, Guido MA, Levey AI. Cellular and subcellular localization of the dopamine transporter in rat cortex. Advances in Pharmacology (San Diego, Calif.). 42: 171-4. PMID 9327871 DOI: 10.1016/S1054-3589(08)60720-6  0.283
2006 Dodson SE, Carter SC, Willnow T, Levey AI, Lah JJ. P1-115: Characterization of PS1/APP mice deficient for the ApoE receptor sorLA/LR11 Alzheimers & Dementia. 2. DOI: 10.1016/J.Jalz.2006.05.491  0.283
2013 Zhou J, Jones DR, Duong DM, Levey AI, Lah JJ, Peng J. Proteomic analysis of postsynaptic density in Alzheimer's disease. Clinica Chimica Acta; International Journal of Clinical Chemistry. 420: 62-8. PMID 23537733 DOI: 10.1016/J.Cca.2013.03.016  0.283
2020 Ahn SI, Sei YJ, Park HJ, Kim J, Ryu Y, Choi JJ, Sung HJ, MacDonald TJ, Levey AI, Kim Y. Microengineered human blood-brain barrier platform for understanding nanoparticle transport mechanisms. Nature Communications. 11: 175. PMID 31924752 DOI: 10.1038/S41467-019-13896-7  0.283
2005 Goldstein FC, Ashley AV, Freedman LJ, Penix L, Lah JJ, Hanfelt J, Levey AI. Hypertension and cognitive performance in African Americans with Alzheimer disease. Neurology. 64: 899-901. PMID 15753433 DOI: 10.1212/01.Wnl.0000152888.26576.37  0.282
2009 Crutcher MD, Calhoun-Haney R, Manzanares CM, Lah JJ, Levey AI, Zola SM. Eye tracking during a visual paired comparison task as a predictor of early dementia. American Journal of Alzheimer's Disease and Other Dementias. 24: 258-66. PMID 19246573 DOI: 10.1177/1533317509332093  0.282
1994 Slowiejko DM, Levey AI, Fisher SK. Sequestration of muscarinic cholinergic receptors in permeabilized neuroblastoma cells. Journal of Neurochemistry. 62: 1795-803. PMID 8158129 DOI: 10.1046/J.1471-4159.1994.62051795.X  0.282
1992 Levey AI, Sisodia SS, Price DL. Advances in the molecular neurobiology of Alzheimerʼs disease Current Opinion in Psychiatry. 5: 98-102. DOI: 10.1097/00001504-199202000-00022  0.282
2020 Higginbotham L, Ping L, Dammer EB, Duong DM, Zhou M, Gearing M, Hurst C, Glass JD, Factor SA, Johnson ECB, Hajjar I, Lah JJ, Levey AI, Seyfried NT. Integrated proteomics reveals brain-based cerebrospinal fluid biomarkers in asymptomatic and symptomatic Alzheimer's disease. Science Advances. 6. PMID 33087358 DOI: 10.1126/sciadv.aaz9360  0.281
2000 Smith Y, Charara A, Hanson JE, Paquet M, Levey AI. GABA(B) and group I metabotropic glutamate receptors in the striatopallidal complex in primates. Journal of Anatomy. 196: 555-76. PMID 10923987 DOI: 10.1017/S0021878299006032  0.281
1997 Hersch SM, Yi H, Heilman CJ, Edwards RH, Levey AI. Subcellular localization and molecular topology of the dopamine transporter in the striatum and substantia nigra. The Journal of Comparative Neurology. 388: 211-27. PMID 9368838 DOI: 10.1002/(Sici)1096-9861(19971117)388:2<211::Aid-Cne3>3.0.Co;2-4  0.28
1997 Tigges M, Tigges J, Rees H, Rye D, Levey AI. Distribution of muscarinic cholinergic receptor proteins m1 to m4 in area 17 of normal and monocularly deprived rhesus monkeys. The Journal of Comparative Neurology. 388: 130-45. PMID 9364243 DOI: 10.1002/(Sici)1096-9861(19971110)388:1<130::Aid-Cne9>3.0.Co;2-2  0.279
2014 Gallagher MD, Suh E, Grossman M, Elman L, McCluskey L, Van Swieten JC, Al-Sarraj S, Neumann M, Gelpi E, Ghetti B, Rohrer JD, Halliday G, Van Broeckhoven C, Seilhean D, Shaw PJ, ... ... Levey A, et al. TMEM106B is a genetic modifier of frontotemporal lobar degeneration with C9orf72 hexanucleotide repeat expansions. Acta Neuropathologica. 127: 407-18. PMID 24442578 DOI: 10.1007/S00401-013-1239-X  0.279
1998 Lewis DA, Sesack SR, Levey AI, Rosenberg DR. Dopamine axons in primate prefrontal cortex: specificity of distribution, synaptic targets, and development. Advances in Pharmacology (San Diego, Calif.). 42: 703-6. PMID 9327996 DOI: 10.1016/S1054-3589(08)60845-5  0.279
2021 Li HD, Funk CC, McFarland K, Dammer EB, Allen M, Carrasquillo MM, Levties Y, Chakrabarty P, Burgess JD, Wang X, Dickson D, Seyfried NT, Duong DM, Lah JJ, Younkin SG, ... Levey AI, et al. Integrative functional genomic analysis of intron retention in human and mouse brain with Alzheimer's disease. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 33480174 DOI: 10.1002/alz.12254  0.278
2020 Lanctôt KL, Scherer RW, Li A, Vieira D, Coulibaly H, Rosenberg PB, Herrmann N, Lerner AJ, Padala PR, Brawman-Mintzer O, van Dyck CH, Porsteinsson AP, Craft S, Levey A, Burke WJ, et al. Measuring Apathy in Alzheimer's Disease in the Apathy in Dementia Methylphenidate Trial 2 (ADMET 2): A Comparison of Instruments. The American Journal of Geriatric Psychiatry : Official Journal of the American Association For Geriatric Psychiatry. PMID 32565008 DOI: 10.1016/J.Jagp.2020.05.020  0.278
1995 Rothstein JD, Van Kammen M, Levey AI, Martin LJ, Kuncl RW. Selective loss of glial glutamate transporter GLT-1 in amyotrophic lateral sclerosis. Annals of Neurology. 38: 73-84. PMID 7611729 DOI: 10.1002/Ana.410380114  0.278
2014 Chen X, Huddleston DE, Langley J, Ahn S, Barnum CJ, Factor SA, Levey AI, Hu X. Simultaneous imaging of locus coeruleus and substantia nigra with a quantitative neuromelanin MRI approach. Magnetic Resonance Imaging. 32: 1301-6. PMID 25086330 DOI: 10.1016/J.Mri.2014.07.003  0.278
2023 Watson CM, Dammer EB, Ping L, Duong DM, Modeste E, Carter EK, Johnson ECB, Levey AI, Lah JJ, Roberts BR, Seyfried NT. Quantitative Mass Spectrometry Analysis of Cerebrospinal Fluid Protein Biomarkers in Alzheimer's Disease. Scientific Data. 10: 261. PMID 37160957 DOI: 10.1038/s41597-023-02158-3  0.278
2004 Salazar G, Love R, Werner E, Doucette MM, Cheng S, Levey A, Faundez V. The zinc transporter ZnT3 interacts with AP-3 and it is preferentially targeted to a distinct synaptic vesicle subpopulation. Molecular Biology of the Cell. 15: 575-87. PMID 14657250 DOI: 10.1091/Mbc.E03-06-0401  0.278
1998 Emborg ME, Ma SY, Mufson EJ, Levey AI, Taylor MD, Brown WD, Holden JE, Kordower JH. Age-related declines in nigral neuronal function correlate with motor impairments in rhesus monkeys. The Journal of Comparative Neurology. 401: 253-65. PMID 9822152 DOI: 10.1002/(Sici)1096-9861(19981116)401:2<253::Aid-Cne7>3.0.Co;2-X  0.277
2008 Li L, Cao D, Desmond R, Rahman A, Lah JJ, Levey AI, Zamrini E. Cognitive performance and plasma levels of homocysteine, vitamin B12, folate and lipids in patients with Alzheimer disease. Dementia and Geriatric Cognitive Disorders. 26: 384-90. PMID 18931498 DOI: 10.1159/000164271  0.277
2000 Prince HC, Tzingounis AV, Levey AI, Conn PJ. Functional downregulation of GluR2 in piriform cortex of kindled animals. Synapse (New York, N.Y.). 38: 489-98. PMID 11044897 DOI: 10.1002/1098-2396(20001215)38:4<489::AID-SYN15>3.0.CO;2-N  0.276
2023 Tandon R, Levey AI, Lah JJ, Seyfried NT, Mitchell CS. Machine Learning Selection of Most Predictive Brain Proteins Suggests Role of Sugar Metabolism in Alzheimer's Disease. Journal of Alzheimer's Disease : Jad. PMID 36776048 DOI: 10.3233/JAD-220683  0.276
2023 Dammer EB, Shantaraman A, Ping L, Duong DM, Gerasimov ES, Ravindran SP, Gudmundsdottir V, Frick EA, Gomez GT, Walker KA, Emilsson V, Jennings LL, Gudnason V, Western D, Cruchaga C, ... ... Levey AI, et al. Proteomic Network Analysis of Alzheimer's Disease Cerebrospinal Fluid Reveals Alterations Associated with ε4 Genotype and Atomoxetine Treatment. Medrxiv : the Preprint Server For Health Sciences. PMID 37961720 DOI: 10.1101/2023.10.29.23297651  0.276
2002 Li DP, Chen SR, Pan YZ, Levey AI, Pan HL. Role of presynaptic muscarinic and GABA(B) receptors in spinal glutamate release and cholinergic analgesia in rats. The Journal of Physiology. 543: 807-18. PMID 12231640 DOI: 10.1113/jphysiol.2002.020644  0.276
2021 Wingo AP, Liu Y, Gerasimov ES, Gockley J, Logsdon BA, Duong DM, Dammer EB, Robins C, Beach TG, Reiman EM, Epstein MP, De Jager PL, Lah JJ, Bennett DA, Seyfried NT, ... Levey AI, et al. Integrating human brain proteomes with genome-wide association data implicates new proteins in Alzheimer's disease pathogenesis. Nature Genetics. PMID 33510477 DOI: 10.1038/s41588-020-00773-z  0.275
2008 Simon ES, Dwolatzky T, Goldstein F, Doniger GM, Levey AI, Lah J, Friger M. P1-170: Non-verbal memory performance is associated with conversion to dementia within one year: A prospective study of mild cognitive impairment using computerized cognitive assessment Alzheimer's & Dementia. 4: T258-T258. DOI: 10.1016/J.Jalz.2008.05.758  0.275
2001 Gilmor M, Heilman C, Nash N, Levey A. UNIT 5.7 Production of Antisera Using Fusion Proteins Current Protocols in Protein Science. DOI: 10.1002/0471142301.Ns0507S00  0.273
2010 Hata S, Urakami K, Fagan A, Peskind E, Akatsu H, Maeda M, Levey A, Chung KA, Montine T, Leverenz J, Goate A, Bateman R, Holtzman DM, Gandy S, Suzuki T. P3-171: Gamma-secretase dysfunction in sporadic Alzhemer's disease suggested by p3-Alc peptide, metabolic product of Alcadein Alzheimer's & Dementia. 6: S499-S500. DOI: 10.1016/J.Jalz.2010.05.1669  0.273
2012 Hermida AP, McDonald WM, Steenland K, Levey A. The association between late-life depression, mild cognitive impairment and dementia: is inflammation the missing link? Expert Review of Neurotherapeutics. 12: 1339-1350. PMID 23234395 DOI: 10.1586/Ern.12.127  0.273
2011 Naj AC, Jun G, Beecham GW, Wang LS, Vardarajan BN, Buros J, Gallins PJ, Buxbaum JD, Jarvik GP, Crane PK, Larson EB, Bird TD, Boeve BF, Graff-Radford NR, De Jager PL, ... ... Levey AI, et al. Common variants at MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 are associated with late-onset Alzheimer's disease. Nature Genetics. 43: 436-41. PMID 21460841 DOI: 10.1038/Ng.801  0.272
2020 Wingo TS, Liu Y, Lori A, Gerasimov ES, Duong DM, Dammer E, Ressler K, Lah J, Bennett D, Seyfried NT, Levey AI, Wingo A. Human Brain Proteome-Wide Association Study of Depression Identified 24 Proteins as Tractable Targets for Further Mechanistic Studies Biological Psychiatry. 87. DOI: 10.1016/J.Biopsych.2020.02.480  0.272
2023 Cruchaga C, Western D, Timsina J, Wang L, Wang C, Yang C, Ali M, Beric A, Gorijala P, Kohlfeld P, Budde J, Levey A, Morris J, Perrin R, Ruiz A, et al. Proteogenomic analysis of human cerebrospinal fluid identifies neurologically relevant regulation and informs causal proteins for Alzheimer's disease. Research Square. PMID 37333337 DOI: 10.21203/rs.3.rs-2814616/v1  0.272
1998 Gearing M, Levey AI, Jones R, Walton W, Shoffner JM, Schmidt ML, Trojanowski JO, Ghelti B, Mirra SS. TAU CYTOPATHOLOGY IN A PATIENT WITH FAMILIAL EARLY ONSET DEMENTIA Journal of Neuropathology and Experimental Neurology. 57: 509. DOI: 10.1097/00005072-199805000-00178  0.271
2021 Lagomarsino VN, Pearse RV, Liu L, Hsieh YC, Fernandez MA, Vinton EA, Paull D, Felsky D, Tasaki S, Gaiteri C, Vardarajan B, Lee H, Muratore CR, Benoit CR, Chou V, ... ... Levey AI, et al. Stem cell-derived neurons reflect features of protein networks, neuropathology, and cognitive outcome of their aged human donors. Neuron. PMID 34473944 DOI: 10.1016/j.neuron.2021.08.003  0.271
2000 Wang JY, Wigston DJ, Rees HD, Levey AI, Falls DL. LIM kinase 1 accumulates in presynaptic terminals during synapse maturation. The Journal of Comparative Neurology. 416: 319-34. PMID 10602091 DOI: 10.1002/(Sici)1096-9861(20000117)416:3<319::Aid-Cne4>3.0.Co;2-Q  0.27
1999 Jansson A, Goldstein M, Tinner B, Zoli M, Meador-Woodruff JH, Lew JY, Levey AI, Watson S, Agnati LF, Fuxe K. On the distribution patterns of D1, D2, tyrosine hydroxylase and dopamine transporter immunoreactivities in the ventral striatum of the rat. Neuroscience. 89: 473-89. PMID 10077329 DOI: 10.1016/S0306-4522(98)00317-0  0.27
2019 Wingo TS, Yang J, Canon SM, Logsdon BA, Seyfried NT, Lah JJ, Levey AI, Boyle PA, Schneider JA, Jager PLD, Bennett DA, Wingo AP. P3-151: Brain Micrornas Associated With Late-Life Depression Are Also Linked To Cognitive Trajectory And Dementia Alzheimers & Dementia. 15. DOI: 10.1016/J.Jalz.2019.06.3180  0.27
2019 Gao T, Xiao H, Ramesha S, Seyfried NT, Levey AI, Rangaraju S. O4-09-02: Regulation Of Pro-Inflammatory And Disease-Associated Microglial Activation By Bin1 Alzheimers & Dementia. 15. DOI: 10.1016/J.Jalz.2019.06.4789  0.27
2000 Charara A, Heilman TC, Levey AI, Smith Y. Pre- and postsynaptic localization of GABA(B) receptors in the basal ganglia in monkeys. Neuroscience. 95: 127-40. PMID 10619469 DOI: 10.1016/S0306-4522(99)00409-1  0.27
2021 Abreha MH, Ojelade S, Dammer EB, McEachin ZT, Duong DM, Gearing M, Bassell GJ, Lah JJ, Levey AI, Shulman JM, Seyfried NT. TBK1 interacts with tau and enhances neurodegeneration in tauopathy. The Journal of Biological Chemistry. 100760. PMID 33965374 DOI: 10.1016/j.jbc.2021.100760  0.27
2012 Steenland K, Karnes C, Seals R, Carnevale C, Hermida A, Levey A. Late-life depression as a risk factor for mild cognitive impairment or Alzheimer's disease in 30 US Alzheimer's disease centers Journal of Alzheimer's Disease. 31: 265-275. PMID 22543846 DOI: 10.3233/Jad-2012-111922  0.268
2020 Ping L, Kundinger SR, Duong DM, Yin L, Gearing M, Lah JJ, Levey AI, Seyfried NT. Global quantitative analysis of the human brain proteome and phosphoproteome in Alzheimer's disease. Scientific Data. 7: 315. PMID 32985496 DOI: 10.1038/s41597-020-00650-8  0.267
2002 Glass JD, Culver DG, Levey AI, Nash NR. Very early activation of m-calpain in peripheral nerve during Wallerian degeneration. Journal of the Neurological Sciences. 196: 9-20. PMID 11959150 DOI: 10.1016/S0022-510X(02)00013-8  0.267
1996 Bradley SR, Levey AI, Hersch SM, Jeffrey P. Use of specific antibodies for studying mGluR subtypes in rat brain Neuropharmacology. 35. DOI: 10.1016/0028-3908(96)84665-X  0.266
2019 Wingo AP, Schneider JA, Breen MS, Seyfried NT, Yang H, Lah JJ, Levey AI, Jin P, Bennett DA, Jager PLD, Wingo TS. P4-107: Brain Micrornas Are Associated With Variation In Cognitive Trajectory In Advanced Age Alzheimers & Dementia. 15. DOI: 10.1016/J.Jalz.2019.06.3768  0.265
2009 Wang L, Goldstein FC, Veledar E, Levey AI, Lah JJ, Meltzer CC, Holder CA, Mao H. Alterations in cortical thickness and white matter integrity in mild cognitive impairment measured by whole-brain cortical thickness mapping and diffusion tensor imaging. Ajnr. American Journal of Neuroradiology. 30: 893-9. PMID 19279272 DOI: 10.3174/Ajnr.A1484  0.265
1997 Jaarsma D, Ruigrok TJ, Caffé R, Cozzari C, Levey AI, Mugnaini E, Voogd J. Cholinergic innervation and receptors in the cerebellum. Progress in Brain Research. 114: 67-96. PMID 9193139 DOI: 10.1016/S0079-6123(08)63359-2  0.265
1997 Miller HP, Levey AI, Rothstein JD, Tzingounis AV, Conn PJ. Alterations in glutamate transporter protein levels in kindling-induced epilepsy. Journal of Neurochemistry. 68: 1564-70. PMID 9084427 DOI: 10.1046/J.1471-4159.1997.68041564.X  0.264
1997 Kish SJ, Guttman M, Robitaille Y, el-Awar M, Chang LJ, Levey AI. Striatal dopamine nerve terminal markers but not nigral cellularity are reduced in spinocerebellar ataxia type 1. Neurology. 48: 1109-11. PMID 9109912 DOI: 10.1212/Wnl.48.4.1109  0.264
1995 Prince HK, Conn PJ, Blackstone CD, Huganir RL, Levey AI. Down-regulation of AMPA receptor subunit GluR2 in amygdaloid kindling. Journal of Neurochemistry. 64: 462-5. PMID 7798948 DOI: 10.1046/J.1471-4159.1995.64010462.X  0.264
2023 Lah J, Tandon R, Zhao L, Watson C, Elmor M, Heilman C, Sanders K, Hales C, Yang H, Loring D, Goldstein F, Hanfelt J, Duong D, Johnson ECB, Wingo A, ... ... Levey A, et al. Predictors of Cognitive Decline in Healthy Middle-Aged Individuals with Asymptomatic Alzheimer's Disease. Research Square. PMID 36909654 DOI: 10.21203/rs.3.rs-2577025/v1  0.264
2010 Van Deerlin VM, Sleiman PM, Martinez-Lage M, Chen-Plotkin A, Wang LS, Graff-Radford NR, Dickson DW, Rademakers R, Boeve BF, Grossman M, Arnold SE, Mann DM, Pickering-Brown SM, Seelaar H, Heutink P, ... ... Levey AI, et al. Common variants at 7p21 are associated with frontotemporal lobar degeneration with TDP-43 inclusions. Nature Genetics. 42: 234-9. PMID 20154673 DOI: 10.1038/Ng.536  0.263
1996 Gu HH, Ahn J, Caplan MJ, Blakely RD, Levey AI, Rudnick G. Cell-specific sorting of biogenic amine transporters expressed in epithelial cells. The Journal of Biological Chemistry. 271: 18100-6. PMID 8663573 DOI: 10.1074/Jbc.271.30.18100  0.263
2009 McConnell GC, Rees HD, Levey AI, Gutekunst CA, Gross RE, Bellamkonda RV. Implanted neural electrodes cause chronic, local inflammation that is correlated with local neurodegeneration. Journal of Neural Engineering. 6: 056003. PMID 19700815 DOI: 10.1088/1741-2560/6/5/056003  0.262
2023 Dai L, Gao F, Wang Q, Lv X, Cheng Z, Wu Y, Chai X, Zetterberg H, Blennow K, Levey AI, Shi J, Shen Y. Molecules of senescent glial cells differentiate Alzheimer's disease from ageing. Journal of Neurology, Neurosurgery, and Psychiatry. PMID 37012067 DOI: 10.1136/jnnp-2022-330743  0.262
1995 Fryer AD, Elbon CL, Jordan KE, Levey AI. Guinea-pig tracheal parasympathetic nerves in primary culture express M2 muscarinic receptors Life Sciences. 56: 1044. DOI: 10.1016/0024-3205(95)93800-T  0.262
2000 Kim SH, Lah JJ, Thinakaran G, Levey A, Sisodia SS. Subcellular localization of presenilins: association with a unique membrane pool in cultured cells. Neurobiology of Disease. 7: 99-117. PMID 10783294 DOI: 10.1006/Nbdi.1999.0280  0.261
2023 Haque R, Watson CM, Liu J, Carter EK, Duong DM, Lah JJ, Wingo AP, Roberts BR, Johnson ECB, Saykin AJ, Shaw LM, Seyfried NT, Wingo TS, Levey AI. A protein panel in cerebrospinal fluid for diagnostic and predictive assessment of Alzheimer's disease. Science Translational Medicine. 15: eadg4122. PMID 37672565 DOI: 10.1126/scitranslmed.adg4122  0.261
2022 Chatterjee P, Vermunt L, Gordon BA, Pedrini S, Boonkamp L, Armstrong NJ, Xiong C, Singh AK, Li Y, Sohrabi HR, Taddei K, Molloy M, Benzinger TLS, Morris JC, Karch C, ... ... Levey A, et al. Plasma glial fibrillary acidic protein in autosomal dominant Alzheimer's disease: Associations with Aβ-PET, neurodegeneration, and cognition. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 36576155 DOI: 10.1002/alz.12879  0.26
2005 Goldstein FC, Dwolatzky T, Doniger GM, Levey AI, Lah JJ, Simon ES. [P-030]: Common pattern of deficit in multinational MCI cohort identified by objective computerized cognitive assessment Alzheimer's & Dementia. 1: S18-S18. DOI: 10.1016/J.Jalz.2005.06.092  0.259
2024 Ahmed H, Wang Y, Griffiths WJ, Levey AI, Pikuleva I, Liang SH, Haider A. Brain cholesterol and Alzheimer's disease: challenges and opportunities in probe and drug development. Brain : a Journal of Neurology. PMID 38301270 DOI: 10.1093/brain/awae028  0.259
1996 Lee FJ, Pristupa ZB, Ciliax BJ, Levey AI, Niznik HB. The dopamine transporter carboxyl-terminal tail. Truncation/substitution mutants selectively confer high affinity dopamine uptake while attenuating recognition of the ligand binding domain. The Journal of Biological Chemistry. 271: 20885-94. PMID 8702845 DOI: 10.1074/jbc.271.34.20885  0.259
2013 Goldstein FC, Levey AI, Steenland NK. High blood pressure and cognitive decline in mild cognitive impairment. Journal of the American Geriatrics Society. 61: 67-73. PMID 23301925 DOI: 10.1111/jgs.12067  0.257
2022 Batra R, Arnold M, Wörheide MA, Allen M, Wang X, Blach C, Levey AI, Seyfried NT, Ertekin-Taner N, Bennett DA, Kastenmüller G, Kaddurah-Daouk RF, Krumsiek J. The landscape of metabolic brain alterations in Alzheimer's disease. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 35829654 DOI: 10.1002/alz.12714  0.256
2020 Wingo TS, Yang J, Fan W, Min Canon S, Gerasimov ES, Lori A, Logsdon B, Yao B, Seyfried NT, Lah JJ, Levey AI, Boyle PA, Schneider JA, De Jager PL, Bennett DA, et al. Brain microRNAs associated with late-life depressive symptoms are also associated with cognitive trajectory and dementia. Npj Genomic Medicine. 5: 6. PMID 32047652 DOI: 10.1038/S41525-019-0113-8  0.255
2024 Shen Y, Ali M, Timsina J, Wang C, Do A, Western D, Liu M, Gorijala P, Budde J, Liu H, Gordon B, McDade E, Morris JC, Llibre-Guerra JJ, Bateman RJ, ... ... Levey AI, et al. Systematic proteomics in Autosomal dominant Alzheimer's disease reveals decades-early changes of CSF proteins in neuronal death, and immune pathways. Medrxiv : the Preprint Server For Health Sciences. PMID 38260583 DOI: 10.1101/2024.01.12.24301242  0.255
2012 Yamout K, Goldstein FC, Lah JJ, Levey AI, Bliwise DL. Neurocognitive correlates of nocturnal oxygen desaturation in a memory clinic population. Journal of Clinical and Experimental Neuropsychology. 34: 325-32. PMID 22233185 DOI: 10.1080/13803395.2011.642849  0.255
2019 Wingo AP, Dammer EB, Breen MS, Logsdon BA, Duong D, Troncoso JC, Thambisetty M, Beach TG, Serrano GE, Reiman EM, Caselli RJ, Lah JJ, Seyfried NT, Levey AI, Wingo TS. O4-10-04: LARGE-SCALE PROTEOMIC ANALYSIS OF HUMAN PREFRONTAL CORTEX IDENTIFIES PROTEINS ASSOCIATED WITH COGNITIVE TRAJECTORY IN ADVANCED AGE Alzheimer's & Dementia. 15: P1260-P1260. DOI: 10.1016/J.Jalz.2019.06.4797  0.254
2019 Nelson PT, Dickson DW, Trojanowski JQ, Jack CR, Boyle PA, Arfanakis K, Rademakers R, Alafuzoff I, Attems J, Brayne C, Coyle-Gilchrist ITS, Chui HC, Fardo DW, Flanagan ME, Halliday G, ... ... Levey AI, et al. Erratum: Limbic-predominant age-related TDP-43 encephalopathy (LATE): consensus working group report. (Brain (2019) 142, (1503–1527) DOI: 10.1093/brain/awz099) Brain. 142. PMID 31147685 DOI: 10.1093/Brain/Awz163  0.253
1991 Weiner DM, Levey AI, Sunahara RK, Niznik HB, O'Dowd BF, Seeman P, Brann MR. D1 and D2 dopamine receptor mRNA in rat brain. Proceedings of the National Academy of Sciences of the United States of America. 88: 1859-63. PMID 1825729 DOI: 10.1073/Pnas.88.5.1859  0.253
2021 Yu L, Boyle PA, Wingo AP, Yang J, Wang T, Buchman AS, Wingo TS, Seyfried NT, Levey AI, De Jager PL, Schneider JA, Bennett DA. Neuropathologic Correlates of Human Cortical Proteins in Alzheimer Disease and Related Dementias. Neurology. PMID 34937778 DOI: 10.1212/WNL.0000000000013252  0.252
1995 Hersch SM, Ciliax BJ, Gutekunst CA, Rees HD, Heilman CJ, Yung KK, Bolam JP, Ince E, Yi H, Levey AI. Electron microscopic analysis of D1 and D2 dopamine receptor proteins in the dorsal striatum and their synaptic relationships with motor corticostriatal afferents. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 15: 5222-37. PMID 7623147 DOI: 10.1523/Jneurosci.15-07-05222.1995  0.252
1997 Schroeter S, Levey AI, Blakely RD. Polarized expression of the antidepressant-sensitive serotonin transporter in epinephrine-synthesizing chromaffin cells of the rat adrenal gland. Molecular and Cellular Neurosciences. 9: 170-84. PMID 9245500 DOI: 10.1006/mcne.1997.0619  0.25
2020 Suver CM, Hamann JK, Chin EM, Goldstein FC, Blazel HM, Manzanares CM, Doerr MJ, Asthana SJ, Mangravite LM, Levey AI, Lah JJ, Edwards DF. Informed Consent in Two Alzheimer's Disease Research Centers: Insights From Research Coordinators. Ajob Empirical Bioethics. 1-11. PMID 32175821 DOI: 10.1080/23294515.2020.1737982  0.249
1998 Erickson SL, Akil M, Levey AI, Lewis DA. Postnatal development of tyrosine hydroxylase- and dopamine transporter-immunoreactive axons in monkey rostral entorhinal cortex. Cerebral Cortex (New York, N.Y. : 1991). 8: 415-27. PMID 9722085 DOI: 10.1093/Cercor/8.5.415  0.249
2022 Hajjar I, Okafor M, Wan L, Yang Z, Nye JA, Bohsali A, Shaw LM, Levey AI, Lah JJ, Calhoun VD, Moore RH, Goldstein FC. Safety and biomarker effects of candesartan in non-hypertensive adults with prodromal Alzheimer's disease. Brain Communications. 4: fcac270. PMID 36440097 DOI: 10.1093/braincomms/fcac270  0.249
1998 Mufson EJ, Jaffar S, Levey AI. m2 muscarinic acetylcholine receptor-immunoreactive neurons are not reduced within the nucleus basalis in Alzheimer's disease: relationship with cholinergic and galaninergic perikarya. The Journal of Comparative Neurology. 392: 313-29. PMID 9511920 DOI: 10.1002/(SICI)1096-9861(19980316)392:3<313::AID-CNE3>3.0.CO;2-4  0.249
2021 Guo Q, Dammer EB, Zhou M, Kundinger SR, Gearing M, Lah JJ, Levey AI, Shulman JM, Seyfried NT. Targeted Quantification of Detergent-Insoluble RNA-Binding Proteins in Human Brain Reveals Stage and Disease Specific Co-aggregation in Alzheimer's Disease. Frontiers in Molecular Neuroscience. 14: 623659. PMID 33815056 DOI: 10.3389/fnmol.2021.623659  0.249
2010 Zeng F, Alagille D, Tamagnan GD, Ciliax BJ, Levey AI, Goodman MM. Synthesis and In Vitro Evaluation of Imidazo[1,2-b]pyridazines as Ligands for β-Amyloid Plaques. Acs Medicinal Chemistry Letters. 1: 80-4. PMID 24900181 DOI: 10.1021/ml100005j  0.249
2013 Steenland K, Zhao L, Goldstein FC, Levey AI. Statins and cognitive decline in older adults with normal cognition or mild cognitive impairment. Journal of the American Geriatrics Society. 61: 1449-55. PMID 24000778 DOI: 10.1111/jgs.12414  0.248
2023 Borkowski K, Seyfried NT, Arnold M, Lah JJ, Levey AI, Hales CM, Dammer EB, Blach C, Louie G, Kaddurah-Daouk R, Newman JW. Integration of plasma and CSF metabolomics with CSF proteomic reveals novel associations between lipid mediators and central nervous system vascular and energy metabolism. Scientific Reports. 13: 13752. PMID 37612324 DOI: 10.1038/s41598-023-39737-8  0.248
2021 Hampel H, Nisticò R, Seyfried NT, Levey AI, Modeste E, Lemercier P, Baldacci F, Toschi N, Garaci F, Perry G, Emanuele E, Valenzuela PL, Lucía A, Urbani A, Sancesario GM, et al. Omics Sciences for Systems Biology in Alzheimer's Disease: State-of-the-Art of the Evidence. Ageing Research Reviews. 101346. PMID 33915266 DOI: 10.1016/j.arr.2021.101346  0.247
2022 Dammer EB, Ping L, Duong DM, Modeste ES, Seyfried NT, Lah JJ, Levey AI, Johnson ECB. Multi-platform proteomic analysis of Alzheimer's disease cerebrospinal fluid and plasma reveals network biomarkers associated with proteostasis and the matrisome. Alzheimer's Research & Therapy. 14: 174. PMID 36384809 DOI: 10.1186/s13195-022-01113-5  0.247
2018 Anttila V, Bulik-Sullivan B, Finucane HK, Walters RK, Bras J, Duncan L, Escott-Price V, Falcone GJ, Gormley P, Malik R, Patsopoulos NA, Ripke S, Wei Z, Yu D, ... ... Levey AI, et al. Analysis of shared heritability in common disorders of the brain. Science (New York, N.Y.). 360. PMID 29930110 DOI: 10.1126/Science.Aap8757  0.246
2002 West A, Periquet M, Lincoln S, Lücking CB, Nicholl D, Bonifati V, Rawal N, Gasser T, Lohmann E, Deleuze JF, Maraganore D, Levey A, Wood N, Dürr A, Hardy J, et al. Complex relationship between Parkin mutations and Parkinson disease. American Journal of Medical Genetics. 114: 584-91. PMID 12116199 DOI: 10.1002/Ajmg.10525  0.246
2005 Charara A, Pare JF, Levey AI, Smith Y. Synaptic and extrasynaptic GABA-A and GABA-B receptors in the globus pallidus: an electron microscopic immunogold analysis in monkeys. Neuroscience. 131: 917-33. PMID 15749345 DOI: 10.1016/j.neuroscience.2004.12.004  0.245
1996 Wilson JM, Kalasinsky KS, Levey AI, Bergeron C, Reiber G, Anthony RM, Schmunk GA, Shannak K, Haycock JW, Kish SJ. Striatal dopamine nerve terminal markers in human, chronic methamphetamine users. Nature Medicine. 2: 699-703. PMID 8640565 DOI: 10.1038/Nm0696-699  0.244
2006 Balaraman Y, Limaye AR, Levey AI, Srinivasan S. Glycogen synthase kinase 3beta and Alzheimer's disease: pathophysiological and therapeutic significance. Cellular and Molecular Life Sciences : Cmls. 63: 1226-35. PMID 16568235 DOI: 10.1007/s00018-005-5597-y  0.243
2006 Simon ES, Goldstein FC, Dwolatzky T, Levey AI, Lah JJ, Doniger GM. P2-181: A prospective study of cognitive performance in amnestic MCI using comprehensive computerized assessment Alzheimer's & Dementia. 2: S288-S288. DOI: 10.1016/J.Jalz.2006.05.1019  0.243
2023 Modeste ES, Ping L, Watson CM, Duong DM, Dammer EB, Johnson ECB, Roberts BR, Lah JJ, Levey AI, Seyfried NT. Quantitative proteomics of cerebrospinal fluid from African Americans and Caucasians reveals shared and divergent changes in Alzheimer's disease. Molecular Neurodegeneration. 18: 48. PMID 37468915 DOI: 10.1186/s13024-023-00638-z  0.241
2024 Christensen GM, Li Z, Liang D, Ebelt S, Gearing M, Levey AI, Lah JJ, Wingo A, Wingo T, Hüls A. Association of PM Exposure and Alzheimer Disease Pathology in Brain Bank Donors-Effect Modification by Genotype. Neurology. 102: e209162. PMID 38382009 DOI: 10.1212/WNL.0000000000209162  0.241
2024 Schwinne M, Alonso A, Roberts BR, Hickle S, Verberk IMW, Epenge E, Gikelekele G, Tsengele N, Kavugho I, Mampunza S, Yarasheski KE, Teunissen CE, Stringer A, Levey A, Ikanga J. The Association of Alzheimer's Disease-Related Blood-Based Biomarkers with Cognitive Screening Test Performance in the Congolese Population in Kinshasa. Journal of Alzheimer's Disease : Jad. 97: 1353-1363. PMID 38306056 DOI: 10.3233/JAD-230976  0.241
2012 Helgadottir A, Gretarsdottir S, Thorleifsson G, Holm H, Patel RS, Gudnason T, Jones GT, van Rij AM, Eapen DJ, Baas AF, Tregouet DA, Morange PE, Emmerich J, Lindblad B, Gottsäter A, ... ... Levey AI, et al. Apolipoprotein(a) genetic sequence variants associated with systemic atherosclerosis and coronary atherosclerotic burden but not with venous thromboembolism. Journal of the American College of Cardiology. 60: 722-9. PMID 22898070 DOI: 10.1016/J.Jacc.2012.01.078  0.241
2004 Galvan A, Charara A, Pare JF, Levey AI, Smith Y. Differential subcellular and subsynaptic distribution of GABA(A) and GABA(B) receptors in the monkey subthalamic nucleus. Neuroscience. 127: 709-21. PMID 15283969 DOI: 10.1016/j.neuroscience.2004.05.014  0.24
2023 Schwinne M, Alonso A, Roberts BR, Hickle S, Verberk IM, Epenge E, Gikelekele G, Tsengele N, Kavugho I, Mampunza S, Yarasheski KE, Teunissen CE, Stringer A, Levey A, Ikanga J. The Association of Alzheimer's Disease-related Blood-based Biomarkers with Cognitive Screening Test Performance in the Congolese Population in Kinshasa. Medrxiv : the Preprint Server For Health Sciences. PMID 37693503 DOI: 10.1101/2023.08.28.23294740  0.24
2023 Golde TE, Levey AI. Immunotherapies for Alzheimer's disease. Science (New York, N.Y.). 382: 1242-1244. PMID 38096276 DOI: 10.1126/science.adj9255  0.239
2023 Christensen GM, Li Z, Liang D, Ebelt S, Gearing M, Levey AI, Lah JJ, Wingo AP, Wingo TS, Huels A. Fine particulate air pollution and neuropathology markers of Alzheimer's disease in donors with and without APOE ε4 alleles - results from an autopsy cohort. Medrxiv : the Preprint Server For Health Sciences. PMID 37066193 DOI: 10.1101/2023.04.07.23288288  0.239
2005 Bliwise DL, Lee JH, Wood-Siverio C, Cellar JS, Lah JJ, Levey AI. Feasibility of ambulatory overnight oximetry in consecutive patients in a dementia clinic. Journal of the American Geriatrics Society. 53: 545-6. PMID 15743306 DOI: 10.1111/J.1532-5415.2005.53178_2.X  0.238
1996 Wilson JM, Levey AI, Bergeron C, Kalasinsky K, Ang L, Peretti F, Adams VI, Smialek J, Anderson WR, Shannak K, Deck J, Niznik HB, Kish SJ. Striatal dopamine, dopamine transporter, and vesicular monoamine transporter in chronic cocaine users. Annals of Neurology. 40: 428-39. PMID 8797532 DOI: 10.1002/ana.410400312  0.238
2020 Harerimana N, Liu Y, Gerasimov ES, Robins C, Duong DM, Lah JJ, Bennett DA, Levey AI, Seyfried NT, Wingo TS, Wingo AP. Functional Analyses of Genetic Risk Variants of Depression-Related Phenotypes in the Human Brain Biological Psychiatry. 87. DOI: 10.1016/J.Biopsych.2020.02.460  0.238
2000 Lah JJ, Levey AI. Analysis of the functional role of endosomal presenilin-1 Neurobiology of Aging. 21: 48. DOI: 10.1016/S0197-4580(00)82892-4  0.238
2010 Gretarsdottir S, Baas AF, Thorleifsson G, Holm H, den Heijer M, de Vries JP, Kranendonk SE, Zeebregts CJ, van Sterkenburg SM, Geelkerken RH, van Rij AM, Williams MJ, Boll AP, Kostic JP, Jonasdottir A, ... ... Levey AI, et al. Genome-wide association study identifies a sequence variant within the DAB2IP gene conferring susceptibility to abdominal aortic aneurysm. Nature Genetics. 42: 692-7. PMID 20622881 DOI: 10.1038/Ng.622  0.237
2019 Robins C, Fan W, Boyle PA, Schneider JA, Lah JJ, Levey AI, De Jager PL, Bennett DA, Wingo TS, Wingo AP. P4-117: DO EPIGENETIC AND TRANSCRIPTOMIC PATTERNS EXPLAIN THE ASSOCIATION BETWEEN LATE-LIFE DEPRESSION AND INCREASED RISK FOR DEMENTIA? Alzheimer's & Dementia. 15: P1321-P1321. DOI: 10.1016/J.Jalz.2019.06.3778  0.237
1999 Bradley SR, Standaert DG, Levey AI, Conn PJ. Distribution of group III mGluRs in rat basal ganglia with subtype-specific antibodies. Annals of the New York Academy of Sciences. 868: 531-4. PMID 10414330 DOI: 10.1111/j.1749-6632.1999.tb11322.x  0.236
2021 Borkowski K, Pedersen TL, Seyfried NT, Lah JJ, Levey AI, Hales CM, Dammer EB, Blach C, Louie G, Kaddurah-Daouk R, Newman JW. Association of plasma and CSF cytochrome P450, soluble epoxide hydrolase, and ethanolamide metabolism with Alzheimer's disease. Alzheimer's Research & Therapy. 13: 149. PMID 34488866 DOI: 10.1186/s13195-021-00893-6  0.235
2008 Helgadottir A, Thorleifsson G, Magnusson KP, Grétarsdottir S, Steinthorsdottir V, Manolescu A, Jones GT, Rinkel GJ, Blankensteijn JD, Ronkainen A, Jääskeläinen JE, Kyo Y, Lenk GM, Sakalihasan N, Kostulas K, ... ... Levey AI, et al. The same sequence variant on 9p21 associates with myocardial infarction, abdominal aortic aneurysm and intracranial aneurysm. Nature Genetics. 40: 217-24. PMID 18176561 DOI: 10.1038/Ng.72  0.234
2003 Votaw J, Byas-Smith M, Hua J, Voll R, Martarello L, Levey AI, Bowman FD, Goodman M. Interaction of isoflurane with the dopamine transporter. Anesthesiology. 98: 404-11. PMID 12552200 DOI: 10.1097/00000542-200302000-00021  0.234
2016 Dunn WD, Cobb J, Levey AI, Gutman DA. REDLetr: Workflow and tools to support the migration of legacy clinical data capture systems to REDCap. International Journal of Medical Informatics. PMID 27396629 DOI: 10.1016/j.ijmedinf.2016.06.015  0.234
2007 Helgadottir A, Thorleifsson G, Manolescu A, Gretarsdottir S, Blondal T, Jonasdottir A, Jonasdottir A, Sigurdsson A, Baker A, Palsson A, Masson G, Gudbjartsson DF, Magnusson KP, Andersen K, Levey AI, et al. A common variant on chromosome 9p21 affects the risk of myocardial infarction. Science (New York, N.Y.). 316: 1491-3. PMID 17478679 DOI: 10.1126/Science.1142842  0.233
2003 Byas-Smith M, Votaw J, Hua J, Voll R, Martarello L, Levey AI, Goodman M. Phenylephrine and norepinephrine increase dopamine transporter ligand binding in striatum. Molecular Imaging and Biology : Mib : the Official Publication of the Academy of Molecular Imaging. 5: 217-26. PMID 14499136 DOI: 10.1016/S1536-1632(03)00042-8  0.232
2009 Goldstein FC, Mao H, Wang L, Ni C, Lah JJ, Levey AI. White Matter Integrity and Episodic Memory Performance in Mild Cognitive Impairment: A Diffusion Tensor Imaging Study. Brain Imaging and Behavior. 3: 132-141. PMID 20596297 DOI: 10.1007/S11682-008-9055-Y  0.232
2019 Wingo A, Fan W, Seyfried N, Duong D, Dammer E, Bennett D, Lah J, Levey A, Wingo T. F94. Human Brain Proteome-Wide Association Study of Longitudinally Assessed Late-Life Depression Biological Psychiatry. 85. DOI: 10.1016/J.Biopsych.2019.03.631  0.23
2023 Schultz SA, Shirzadi Z, Schultz AP, Liu L, Fitzpatrick CD, McDade E, Barthelemy NR, Renton A, Esposito B, Joseph-Mathurin N, Cruchaga C, Chen CD, Goate A, Allegri RF, Benzinger TLS, ... ... Levey AI, et al. Location of pathogenic variants in PSEN1 impacts progression of cognitive, clinical, and neurodegenerative measures in autosomal-dominant Alzheimer's disease. Aging Cell. e13871. PMID 37291760 DOI: 10.1111/acel.13871  0.23
2019 Wingo AP, Wingo TS, Fan W, Bergquist S, Alonso A, Marcus M, Levey AI, Lah JJ. Purpose in life is a robust protective factor of reported cognitive decline among late middle-aged adults: The Emory Healthy Aging Study. Journal of Affective Disorders. 263: 310-317. PMID 31969260 DOI: 10.1016/J.Jad.2019.11.124  0.229
2022 Eninger T, Müller SA, Bacioglu M, Schweighauser M, Lambert M, Maia LF, Neher JJ, Hornfeck SM, Obermüller U, Kleinberger G, Haass C, Kahle PJ, Staufenbiel M, Ping L, Duong DM, ... Levey AI, et al. Signatures of glial activity can be detected in the CSF proteome. Proceedings of the National Academy of Sciences of the United States of America. 119: e2119804119. PMID 35666874 DOI: 10.1073/pnas.2119804119  0.229
2004 Ashley AV, Flacker J, Goldstein FC, Freedman LJ, Lah JJ, Levey AI. P1-130 The “Mini-cog” as a screen for dementia: validation in an African American population Neurobiology of Aging. 25: S131-S132. DOI: 10.1016/S0197-4580(04)80443-3  0.228
2004 Choi J, Levey AI, Weintraub ST, Rees HD, Gearing M, Chin LS, Li L. Oxidative modifications and down-regulation of ubiquitin carboxyl-terminal hydrolase L1 associated with idiopathic Parkinson's and Alzheimer's diseases. The Journal of Biological Chemistry. 279: 13256-64. PMID 14722078 DOI: 10.1074/Jbc.M314124200  0.228
2022 Hone-Blanchet A, Bhosali A, Krishnamurthy LC, Shahid SS, Lin Q, Zhao L, Bisht AS, John SE, Loring D, Goldstein F, Levey A, Lah J, Qiu D, Crosson B. Frontal Metabolites and Alzheimer's Disease Biomarkers in Healthy Older Women and Women Diagnosed with Mild Cognitive Impairment. Journal of Alzheimer's Disease : Jad. PMID 35431238 DOI: 10.3233/JAD-215431  0.228
2023 Shirzadi Z, Schultz SA, Yau WW, Joseph-Mathurin N, Fitzpatrick CD, Levin R, Kantarci K, Preboske GM, Jack CR, Farlow MR, Hassenstab J, Jucker M, Morris JC, Xiong C, Karch CM, ... Levey AI, et al. Etiology of White Matter Hyperintensities in Autosomal Dominant and Sporadic Alzheimer Disease. Jama Neurology. PMID 37843849 DOI: 10.1001/jamaneurol.2023.3618  0.227
2022 Wu J, Shahid SS, Lin Q, Hone-Blanchet A, Smith JL, Risk BB, Bisht AS, Loring DW, Goldstein FC, Levey AI, Lah JJ, Qiu D. Multimodal magnetic resonance imaging reveals distinct sensitivity of hippocampal subfields in asymptomatic stage of Alzheimer's disease. Frontiers in Aging Neuroscience. 14: 901140. PMID 36034141 DOI: 10.3389/fnagi.2022.901140  0.227
2024 Li Z, Liang D, Ebelt S, Gearing M, Kobor MS, Konwar C, Maclsaac JL, Dever K, Wingo AP, Levey AI, Lah JJ, Wingo TS, Hüls A. Differential DNA methylation in the brain as potential mediator of the association between traffic-related PM and neuropathology markers of Alzheimer's disease. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 38345197 DOI: 10.1002/alz.13650  0.226
2023 Li Z, Liang D, Ebelt S, Gearing M, Kobor MS, Konwar C, Maclsaac JL, Dever K, Wingo A, Levey A, Lah JJ, Wingo T, Huels A. Differential DNA Methylation in the Brain as Potential Mediator of the Association between Traffic-related PM and Neuropathology Markers of Alzheimer's Disease. Medrxiv : the Preprint Server For Health Sciences. PMID 37425713 DOI: 10.1101/2023.06.30.23292085  0.226
2014 Rojas-Fernandez CH, Goldstein LB, Levey AI, Taylor BA, Bittner V, The National Lipid Association's Safety Task Force. An assessment by the Statin Cognitive Safety Task Force: 2014 update. Journal of Clinical Lipidology. 8: S5-16. PMID 24793442 DOI: 10.1016/j.jacl.2014.02.013  0.224
2024 Chung M, Carter EK, Veire AM, Dammer EB, Chang J, Duong DM, Raj N, Bassell GJ, Glass JD, Gendron TF, Nelson PT, Levey AI, Seyfried NT, McEachin ZT. Cryptic exon inclusion is a molecular signature of LATE-NC in aging brains. Acta Neuropathologica. 147: 29. PMID 38308693 DOI: 10.1007/s00401-023-02671-0  0.224
2016 Helgadottir A, Gretarsdottir S, Thorleifsson G, Hjartarson E, Sigurdsson A, Magnusdottir A, Jonasdottir A, Kristjansson H, Sulem P, Oddsson A, Sveinbjornsson G, Steinthorsdottir V, Rafnar T, Masson G, Jonsdottir I, ... ... Levey AI, et al. Variants with large effects on blood lipids and the role of cholesterol and triglycerides in coronary disease. Nature Genetics. PMID 27135400 DOI: 10.1038/ng.3561  0.224
2015 Hajjar I, Wharton W, Mack WJ, Levey AI, Goldstein FC. Racial Disparity in Cognitive and Functional Disability in Hypertension and All-Cause Mortality. American Journal of Hypertension. PMID 26137951 DOI: 10.1093/Ajh/Hpv084  0.223
2013 Yang Z, Lin PJ, Levey A. Monetary costs of dementia in the United States New England Journal of Medicine. 369: 489. PMID 23902509 DOI: 10.1056/NEJMc1305541  0.223
2006 Helgadottir A, Manolescu A, Helgason A, Thorleifsson G, Thorsteinsdottir U, Gudbjartsson DF, Gretarsdottir S, Magnusson KP, Gudmundsson G, Hicks A, Jonsson T, Grant SF, Sainz J, O'Brien SJ, Sveinbjornsdottir S, ... ... Levey AI, et al. A variant of the gene encoding leukotriene A4 hydrolase confers ethnicity-specific risk of myocardial infarction. Nature Genetics. 38: 68-74. PMID 16282974 DOI: 10.1038/Ng1692  0.223
2023 Rajabli F, Benchek P, Tosto G, Kushch N, Sha J, Bazemore K, Zhu C, Lee WP, Haut J, Hamilton-Nelson KL, Wheeler NR, Zhao Y, Farrell JJ, Grunin MA, Leung YY, ... ... Levey AI, et al. Multi-ancestry genome-wide meta-analysis of 56,241 individuals identifies and nominates ancestry-specific loci , , and as novel risk loci for Alzheimer's disease: the Alzheimer's Disease Genetics Consortium. Medrxiv : the Preprint Server For Health Sciences. PMID 37461624 DOI: 10.1101/2023.07.06.23292311  0.222
2012 Zola S, Manzanares C, Clopton P, Lah J, Levey A. P4-376: Behavioral performance as a predictor of cognitive decline: Detecting the transition from healthy aging to mild cognitive impairment Alzheimer's & Dementia. 8: S791-S791. DOI: 10.1016/J.Jalz.2013.08.276  0.221
2017 Baliga NS, Björkegren JL, Boeke JD, Boutros M, Crawford NP, Dudley AM, Farber CR, Jones A, Levey AI, Lusis AJ, Mak HC, Nadeau JH, Noyes MB, Petretto E, Seyfried NT, et al. The State of Systems Genetics in 2017. Cell Systems. 4: 7-15. PMID 28125793 DOI: 10.1016/J.Cels.2017.01.005  0.22
2014 Goldstein FC, Zhao L, Steenland K, Levey AI. Inflammation and cognitive functioning in African Americans and Caucasians. International Journal of Geriatric Psychiatry. PMID 25503371 DOI: 10.1002/Gps.4238  0.219
1995 Levey AI, Edmunds SM, Hersch SM, Wiley RG, Heilman CJ. Light and electron microscopic study of m2 muscarinic acetylcholine receptor in the basal forebrain of the rat. The Journal of Comparative Neurology. 351: 339-56. PMID 7706546 DOI: 10.1002/Cne.903510303  0.219
2021 He Q, Colon-Motas KM, Pybus AF, Piendel L, Seppa JK, Walker ML, Manzanares CM, Qiu D, Miocinovic S, Wood LB, Levey AI, Lah JJ, Singer AC. A feasibility trial of gamma sensory flicker for patients with prodromal Alzheimer's disease. Alzheimer's & Dementia (New York, N. Y.). 7: e12178. PMID 34027028 DOI: 10.1002/trc2.12178  0.217
2016 Goldstein FC, Hajjar IM, Dunn CB, Levey AI, Wharton W. The Relationship Between Cognitive Functioning and the JNC-8 Guidelines for Hypertension in Older Adults. The Journals of Gerontology. Series a, Biological Sciences and Medical Sciences. PMID 27678289 DOI: 10.1093/Gerona/Glw181  0.217
2021 Levey AI. Progress with Treatments for Alzheimer's Disease. The New England Journal of Medicine. 384: 1762-1763. PMID 33951366 DOI: 10.1056/NEJMe2103722  0.216
2023 Lin Q, Shahid S, Hone-Blanchet A, Huang S, Wu J, Bisht A, Loring D, Goldstein F, Levey A, Crosson B, Lah J, Qiu D. Magnetic resonance evidence of increased iron content in subcortical brain regions in asymptomatic Alzheimer's disease. Human Brain Mapping. PMID 36929676 DOI: 10.1002/hbm.26263  0.216
2016 Jin L, Maezawa I, Nguyen HM, Di Lucente J, Rangaraju S, Levey AI, Wulff H. O2-07-05: KV1.3 Inhibition Reduces Ab-Induced Microglial Neurotoxicity Alzheimer's & Dementia. 12: P242-P243. DOI: 10.1016/J.Jalz.2016.06.434  0.215
2019 Nocera JR, Arsik I, Keskinocak P, Lepley-Flood A, Lah JJ, Levey AI, Esper GJ. The Feasibility of Measuring Gait in an Outpatient Cognitive Neurology Clinical Setting. Journal of Alzheimer's Disease : Jad. PMID 31322564 DOI: 10.3233/Jad-190106  0.215
2006 Zeng F, Southerland JA, Voll RJ, Votaw JR, Williams L, Ciliax BJ, Levey AI, Goodman MM. Synthesis and evaluation of two 18F-labeled imidazo[1,2-a]pyridine analogues as potential agents for imaging beta-amyloid in Alzheimer's disease. Bioorganic & Medicinal Chemistry Letters. 16: 3015-8. PMID 16574411 DOI: 10.1016/j.bmcl.2006.02.055  0.215
2023 Higginbotham L, Carter EK, Dammer EB, Haque RU, Johnson ECB, Duong DM, Yin L, De Jager PL, Bennett DA, Felsky D, Tio ES, Lah JJ, Levey AI, Seyfried NT. Unbiased classification of the elderly human brain proteome resolves distinct clinical and pathophysiological subtypes of cognitive impairment. Neurobiology of Disease. 106286. PMID 37689213 DOI: 10.1016/j.nbd.2023.106286  0.213
1997 Lee MK, Borchelt DR, Kim G, Thinakaran G, Slunt HH, Ratovitski T, Martin LJ, Kittur A, Gandy S, Levey AI, Jenkins N, Copeland N, Price DL, Sisodia SS. Hyperaccumulation of FAD-linked presenilin 1 variants in vivo. Nature Medicine. 3: 756-60. PMID 9212102 DOI: 10.1038/Nm0797-756  0.211
2021 Harerimana NV, Liu Y, Gerasimov ES, Duong D, Beach TG, Reiman EM, Schneider JA, Boyle P, Lori A, Bennett DA, Lah JJ, Levey AI, Seyfried NT, Wingo TS, Wingo AP. Genetic Evidence Supporting a Causal Role of Depression in Alzheimer's Disease. Biological Psychiatry. PMID 35177243 DOI: 10.1016/j.biopsych.2021.11.025  0.21
1995 Hersch SM, Levey AI. Diverse pre- and post-synaptic expression of m1-m4 muscarinic receptor proteins in neurons and afferents in the rat neostriatum. Life Sciences. 56: 931-8. PMID 10188795 DOI: 10.1016/0024-3205(95)00030-A  0.21
2022 Wingo TS, Liu Y, Gerasimov ES, Vattathil SM, Wynne ME, Liu J, Lori A, Faundez V, Bennett DA, Seyfried NT, Levey AI, Wingo AP. Shared mechanisms across the major psychiatric and neurodegenerative diseases. Nature Communications. 13: 4314. PMID 35882878 DOI: 10.1038/s41467-022-31873-5  0.209
2023 Britton GB, Huang LK, Villarreal AE, Levey A, Philippakis A, Hu CJ, Yang CC, Mushi D, Oviedo DC, Rangel G, Ho JS, Thompson L, Khemakhem M, Ross M, Carreira MB, et al. Digital phenotyping: An equal opportunity approach to reducing disparities in Alzheimer's disease and related dementia research. Alzheimer's & Dementia (Amsterdam, Netherlands). 15: e12495. PMID 38034851 DOI: 10.1002/dad2.12495  0.209
1996 Rouse ST, Levey AI. Expression of m1-m4 muscarinic acetylcholine receptor immunoreactivity in septohippocampal neurons and other identified hippocampal afferents. The Journal of Comparative Neurology. 375: 406-16. PMID 8915839 DOI: 10.1002/(SICI)1096-9861(19961118)375:3<406::AID-CNE5>3.0.CO;2-6  0.208
2022 Wingo AP, Vattathil SM, Liu J, Fan W, Cutler DJ, Levey AI, Schneider JA, Bennett DA, Wingo TS. LDL cholesterol is associated with higher AD neuropathology burden independent of APOE. Journal of Neurology, Neurosurgery, and Psychiatry. PMID 35772923 DOI: 10.1136/jnnp-2021-328164  0.208
2019 Kunkle BW, Grenier-Boley B, Sims R, Bis JC, Damotte V, Naj AC, Boland A, Vronskaya M, van der Lee SJ, Amlie-Wolf A, Bellenguez C, Frizatti A, Chouraki V, Martin ER, Sleegers K, ... ... Levey AI, et al. Genetic meta-analysis of diagnosed Alzheimer's disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing. Nature Genetics. 51: 414-430. PMID 30820047 DOI: 10.1038/s41588-019-0358-2  0.208
1999 Siddiqui MF, Levey AI. Cholinergic therapies in Alzheimer's disease Drugs of the Future. 24: 417-424. DOI: 10.1358/dof.1999.024.04.668318  0.207
2005 Petersen RC, Thomas RG, Grundman M, Bennett DA, Kaye J, Levey AI, Pfeiffer E, Sano M, van Dyck CH, Thal LJ. [O1-04-04]: Operational criteria for patient recruitment in trials of mild cognitive impairment Alzheimer's & Dementia. 1: S87-S87. DOI: 10.1016/J.Jalz.2005.06.303  0.206
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