Stuart Cobb - Publications

Affiliations: 
1999-2017 University of Glasgow, Glasgow, Scotland, United Kingdom 
 2017- University of Edinburgh, Edinburgh, Scotland, United Kingdom 
Area:
neurophysiology
Website:
https://www.ed.ac.uk/discovery-brain-sciences/our-staff/research-groups/stuart-cobb

62 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2018 Turko P, Groberman K, Browa F, Cobb S, Vida I. Differential Dependence of GABAergic and Glutamatergic Neurons on Glia for the Establishment of Synaptic Transmission. Cerebral Cortex (New York, N.Y. : 1991). PMID 29425353 DOI: 10.1093/cercor/bhy029  1
2017 Hector RD, Kalscheuer VM, Hennig F, Leonard H, Downs J, Clarke A, Benke TA, Armstrong J, Pineda M, Bailey MES, Cobb SR. CDKL5 variants: Improving our understanding of a rare neurologic disorder. Neurology. Genetics. 3: e200. PMID 29264392 DOI: 10.1212/NXG.0000000000000200  0.72
2017 Tillotson R, Selfridge J, Koerner MV, Gadalla KKE, Guy J, De Sousa D, Hector RD, Cobb SR, Bird A. Radically truncated MeCP2 rescues Rett syndrome-like neurological defects. Nature. PMID 29019980 DOI: 10.1038/nature24058  1
2017 Gadalla KKE, Vudhironarit T, Hector RD, Sinnett S, Bahey NG, Bailey MES, Gray SJ, Cobb SR. Development of a Novel AAV Gene Therapy Cassette with Improved Safety Features and Efficacy in a Mouse Model of Rett Syndrome. Molecular Therapy. Methods & Clinical Development. 5: 180-190. PMID 28497075 DOI: 10.1016/j.omtm.2017.04.007  0.72
2017 Sinnett SE, Hector RD, Gadalla KKE, Heindel C, Chen D, Zaric V, Bailey MES, Cobb SR, Gray SJ. Improved MECP2 Gene Therapy Extends the Survival of MeCP2-Null Mice without Apparent Toxicity after Intracisternal Delivery. Molecular Therapy. Methods & Clinical Development. 5: 106-115. PMID 28497072 DOI: 10.1016/j.omtm.2017.04.006  0.72
2016 Ross PD, Guy J, Selfridge J, Kamal B, Bahey N, Tanner KE, Gillingwater TH, Jones RA, Loughrey CM, McCarroll CS, Bailey ME, Bird A, Cobb S. Exclusive expression of MeCP2 in the nervous system distinguishes between brain and peripheral Rett syndrome-like phenotypes. Human Molecular Genetics. 25: 4389-4404. PMID 28173151 DOI: 10.1093/hmg/ddw269  1
2016 Forrest CM, Kennedy PG, Rodgers J, Dalton RN, Turner C, Darlington LG, Cobb S, Stone TW. Kynurenine pathway metabolism following prenatal KMO inhibition and in Mecp2(+/-) mice, using liquid chromatography-tandem mass spectrometry. Neurochemistry International. PMID 27623092 DOI: 10.1016/j.neuint.2016.09.012  1
2016 Ross PD, Guy J, Selfridge J, Kamal B, Bahey N, Tanner E, Gillingwater TH, Jones RA, Loughrey CM, McCarroll CS, Bailey ME, Bird A, Cobb S. Exclusive expression of MeCP2 in the nervous system distinguishes between brain and peripheral Rett syndrome-like phenotypes. Human Molecular Genetics. PMID 27506980 DOI: 10.1093/hmg/ddw269  1
2016 Hector RD, Dando O, Landsberger N, Kilstrup-Nielsen C, Kind PC, Bailey ME, Cobb SR. Characterisation of CDKL5 Transcript Isoforms in Human and Mouse. Plos One. 11: e0157758. PMID 27315173 DOI: 10.1371/journal.pone.0157758  1
2015 Cobb SR. Cognitive disorders: Deep brain stimulation for Rett syndrome. Nature. 526: 331-2. PMID 26469040 DOI: 10.1038/526331a  1
2015 Booker SA, Pires N, Cobb S, Soares-da-Silva P, Vida I. Carbamazepine and oxcarbazepine, but not eslicarbazepine, enhance excitatory synaptic transmission onto hippocampal CA1 pyramidal cells through an antagonist action at adenosine A1 receptors. Neuropharmacology. 93: 103-15. PMID 25656478 DOI: 10.1016/j.neuropharm.2015.01.019  1
2015 Kamal B, Russell D, Payne A, Constante D, Tanner KE, Isaksson H, Mathavan N, Cobb SR. Biomechanical properties of bone in a mouse model of Rett syndrome. Bone. 71: 106-14. PMID 25445449 DOI: 10.1016/j.bone.2014.10.008  1
2015 Saudargiene A, Cobb S, Graham BP. A computational study on plasticity during theta cycles at Schaffer collateral synapses on CA1 pyramidal cells in the hippocampus. Hippocampus. 25: 208-18. PMID 25220633 DOI: 10.1002/hipo.22365  1
2015 Gadalla KKE, Ross PD, Hector RD, Bahey NG, Bailey MES, Cobb SR. Gene therapy for Rett syndrome: Prospects and challenges Future Neurology. 10: 467-483. DOI: 10.2217/fnl.15.29  0.72
2014 Gadalla KK, Ross PD, Riddell JS, Bailey ME, Cobb SR. Gait analysis in a Mecp2 knockout mouse model of Rett syndrome reveals early-onset and progressive motor deficits. Plos One. 9: e112889. PMID 25392929 DOI: 10.1371/journal.pone.0112889  1
2014 Graham BP, Saudargiene A, Cobb S. Spine head calcium as a measure of summed postsynaptic activity for driving synaptic plasticity. Neural Computation. 26: 2194-222. PMID 25058697 DOI: 10.1162/NECO_a_00640  1
2013 Robinson L, Plano A, Cobb S, Riedel G. Long-term home cage activity scans reveal lowered exploratory behaviour in symptomatic female Rett mice. Behavioural Brain Research. 250: 148-56. PMID 23643691 DOI: 10.1016/j.bbr.2013.04.041  1
2013 Cobb SR, Davies CH. Neurodevelopmental disorders. Neuropharmacology. 68: 1. PMID 23402709 DOI: 10.1016/j.neuropharm.2013.02.001  1
2013 McLeod F, Ganley R, Williams L, Selfridge J, Bird A, Cobb SR. Reduced seizure threshold and altered network oscillatory properties in a mouse model of Rett syndrome. Neuroscience. 231: 195-205. PMID 23238573 DOI: 10.1016/j.neuroscience.2012.11.058  1
2013 Gadalla KK, Bailey ME, Spike RC, Ross PD, Woodard KT, Kalburgi SN, Bachaboina L, Deng JV, West AE, Samulski RJ, Gray SJ, Cobb SR. Improved survival and reduced phenotypic severity following AAV9/MECP2 gene transfer to neonatal and juvenile male Mecp2 knockout mice. Molecular Therapy : the Journal of the American Society of Gene Therapy. 21: 18-30. PMID 23011033 DOI: 10.1038/mt.2012.200  1
2012 Robinson L, Guy J, McKay L, Brockett E, Spike RC, Selfridge J, De Sousa D, Merusi C, Riedel G, Bird A, Cobb SR. Morphological and functional reversal of phenotypes in a mouse model of Rett syndrome. Brain : a Journal of Neurology. 135: 2699-710. PMID 22525157 DOI: 10.1093/brain/aws096  1
2011 Weng SM, Bailey ME, Cobb SR. Rett syndrome: from bed to bench. Pediatrics and Neonatology. 52: 309-16. PMID 22192257 DOI: 10.1016/j.pedneo.2011.08.002  1
2011 Barberan S, McNair K, Iqbal K, Smith NC, Prendergast GC, Stone TW, Cobb SR, Morris BJ. Altered apoptotic responses in neurons lacking RhoB GTPase. The European Journal of Neuroscience. 34: 1737-46. PMID 22098422 DOI: 10.1111/j.1460-9568.2011.07891.x  1
2011 Gadalla KK, Bailey ME, Cobb SR. MeCP2 and Rett syndrome: reversibility and potential avenues for therapy. The Biochemical Journal. 439: 1-14. PMID 21916843 DOI: 10.1042/BJ20110648  1
2011 Chartier-Harlin MC, Dachsel JC, Vilariño-Güell C, Lincoln SJ, Leprêtre F, Hulihan MM, Kachergus J, Milnerwood AJ, Tapia L, Song MS, Le Rhun E, Mutez E, Larvor L, Duflot A, Vanbesien-Mailliot C, ... ... Cobb SA, et al. Translation initiator EIF4G1 mutations in familial Parkinson disease. American Journal of Human Genetics. 89: 398-406. PMID 21907011 DOI: 10.1016/j.ajhg.2011.08.009  0.36
2011 Nathan PJ, Cobb SR, Lu B, Bullmore ET, Davies CH. Studying synaptic plasticity in the human brain and opportunities for drug discovery. Current Opinion in Pharmacology. 11: 540-8. PMID 21737346 DOI: 10.1016/j.coph.2011.06.008  1
2011 Gan J, Greenwood SM, Cobb SR, Bushell TJ. Indirect modulation of neuronal excitability and synaptic transmission in the hippocampus by activation of proteinase-activated receptor-2. British Journal of Pharmacology. 163: 984-94. PMID 21366553 DOI: 10.1111/j.1476-5381.2011.01293.x  1
2011 Weng SM, McLeod F, Bailey ME, Cobb SR. Synaptic plasticity deficits in an experimental model of rett syndrome: long-term potentiation saturation and its pharmacological reversal. Neuroscience. 180: 314-21. PMID 21296130 DOI: 10.1016/j.neuroscience.2011.01.061  1
2011 Poland SP, Wright AJ, Cobb S, Vijverberg JC, Girkin JM. A demonstration of the effectiveness of a single aberration correction per optical slice in beam scanned optically sectioning microscopes. Micron (Oxford, England : 1993). 42: 318-23. PMID 20932768 DOI: 10.1016/j.micron.2010.05.018  1
2011 Cutsuridis V, Graham BP, Cobb S, Hasselmo ME. Bio-inspired models of memory capacity, recall performance and theta phase precession in the hippocampus Proceedings of the International Joint Conference On Neural Networks. 3141-3148. DOI: 10.1109/IJCNN.2011.6033637  1
2010 Cobb S, Guy J, Bird A. Reversibility of functional deficits in experimental models of Rett syndrome. Biochemical Society Transactions. 38: 498-506. PMID 20298210 DOI: 10.1042/BST0380498  1
2010 McNair K, Spike R, Guilding C, Prendergast GC, Stone TW, Cobb SR, Morris BJ. A role for RhoB in synaptic plasticity and the regulation of neuronal morphology. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 30: 3508-17. PMID 20203211 DOI: 10.1523/JNEUROSCI.5386-09.2010  1
2010 Cutsuridis V, Cobb S, Graham BP. Encoding and retrieval in a model of the hippocampal CA1 microcircuit. Hippocampus. 20: 423-46. PMID 19489002 DOI: 10.1002/hipo.20661  1
2009 Cutsuridis V, Cobb S, Graham BP. How bursts shape the STDP curve in the presence/absence of GABAergic inhibition Lecture Notes in Computer Science (Including Subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics). 5768: 229-238. DOI: 10.1007/978-3-642-04274-4_24  1
2009 Hunter R, Cobb S, Graham BP. Improving associative memory in a network of spiking neurons Neural Network World. 19: 447-470. DOI: 10.1007/978-3-540-87559-8_66  1
2009 Cutsuridis V, Cobb S, Graham BP. Modelling the STDP symmetry-to-asymmetry transition in the presence of GABAergic inhibition Neural Network World. 19: 471-481.  1
2008 Goodwin RJ, Dungworth JC, Cobb SR, Pitt AR. Time-dependent evolution of tissue markers by MALDI-MS imaging. Proteomics. 8: 3801-8. PMID 18712770 DOI: 10.1002/pmic.200800201  1
2008 Cobb SR, Pitt A. Proteomics in the study of hippocampal plasticity. Expert Review of Proteomics. 5: 393-404. PMID 18532907 DOI: 10.1586/14789450.5.3.393  1
2008 Hunter R, Cobb S, Graham BP. Improving recall in an associative neural network of spiking neurons Lecture Notes in Computer Science (Including Subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics). 5286: 137-141. DOI: 10.1007/978-3-540-88853-6-12  1
2008 Cutsuridis V, Cobb S, Graham BP. A CA2+ dynamics model of the STDP symmetry-to-asymmetry transition in the CA1 pyramidal cell of the hippocampus Lecture Notes in Computer Science (Including Subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics). 5164: 627-635. DOI: 10.1007/978-3-540-87559-8_65  1
2008 Cutsuridis V, Cobb S, Graham BP. Encoding and retrieval in a CA1 microcircuit model of the hippocampus Lecture Notes in Computer Science (Including Subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics). 5164: 238-247. DOI: 10.1007/978-3-540-87559-8_25  1
2007 Yau JL, McNair KM, Noble J, Brownstein D, Hibberd C, Morton N, Mullins JJ, Morris RG, Cobb S, Seckl JR. Enhanced hippocampal long-term potentiation and spatial learning in aged 11beta-hydroxysteroid dehydrogenase type 1 knock-out mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 27: 10487-96. PMID 17898220 DOI: 10.1523/JNEUROSCI.2190-07.2007  1
2007 Shelbourne P, Coote E, Dadak S, Cobb SR. Normal electrical properties of hippocampal neurons modelling early Huntington disease pathogenesis. Brain Research. 1139: 226-34. PMID 17291464 DOI: 10.1016/j.brainres.2006.12.091  1
2007 Guy J, Gan J, Selfridge J, Cobb S, Bird A. Reversal of neurological defects in a mouse model of Rett syndrome. Science (New York, N.Y.). 315: 1143-7. PMID 17289941 DOI: 10.1126/science.1138389  1
2007 McNair K, Broad J, Riedel G, Davies CH, Cobb SR. Global changes in the hippocampal proteome following exposure to an enriched environment. Neuroscience. 145: 413-22. PMID 17261355 DOI: 10.1016/j.neuroscience.2006.12.033  1
2006 Widmer H, Ferrigan L, Davies CH, Cobb SR. Evoked slow muscarinic acetylcholinergic synaptic potentials in rat hippocampal interneurons. Hippocampus. 16: 617-28. PMID 16770798 DOI: 10.1002/hipo.20191  1
2006 Bushell TJ, Plevin R, Cobb S, Irving AJ. Characterization of proteinase-activated receptor 2 signalling and expression in rat hippocampal neurons and astrocytes. Neuropharmacology. 50: 714-25. PMID 16430928 DOI: 10.1016/j.neuropharm.2005.11.024  1
2006 Gill CH, Brown JT, Shivji N, Lappin SC, Farmer C, Randall A, McNaughton NC, Cobb SR, Davies CH. Inhibition of Ih reduces epileptiform activity in rodent hippocampal slices. Synapse (New York, N.Y.). 59: 308-16. PMID 16421904 DOI: 10.1002/syn.20242  1
2006 McNair K, Davies CH, Cobb SR. Plasticity-related regulation of the hippocampal proteome. The European Journal of Neuroscience. 23: 575-80. PMID 16420465 DOI: 10.1111/j.1460-9568.2005.04542.x  1
2005 Cobb SR, Davies CH. Cholinergic modulation of hippocampal cells and circuits. The Journal of Physiology. 562: 81-8. PMID 15528238 DOI: 10.1113/jphysiol.2004.076539  1
2003 Roshan-Milani S, Ferrigan L, Khoshnood MJ, Davies CH, Cobb SR. Regulation of epileptiform activity in hippocampus by nicotinic acetylcholine receptor activation. Epilepsy Research. 56: 51-65. PMID 14529953 DOI: 10.1016/j.eplepsyres.2003.08.005  1
2003 Cobb SR, Larkman PM, Bulters DO, Oliver L, Gill CH, Davies CH. Activation of Ih is necessary for patterning of mGluR and mAChR induced network activity in the hippocampal CA3 region. Neuropharmacology. 44: 293-303. PMID 12604089 DOI: 10.1016/S0028-3908(02)00405-7  1
2002 Lanneau C, Harries MH, Ray AM, Cobb SR, Randall A, Davies CH. Complex interactions between mGluR1 and mGluR5 shape neuronal network activity in the rat hippocampus. Neuropharmacology. 43: 131-40. PMID 12213267 DOI: 10.1016/S0028-3908(02)00086-2  1
2001 Morton RA, Manuel NA, Bulters DO, Cobb SR, Davies CH. Regulation of muscarinic acetylcholine receptor-mediated synaptic responses by GABA(B) receptors in the rat hippocampus. The Journal of Physiology. 535: 757-66. PMID 11559773 DOI: 10.1111/j.1469-7793.2001.00757.x  1
2000 Cobb SR, Bulters DO, Davies CH. Coincident activation of mGluRs and mAChRs imposes theta frequency patterning on synchronised network activity in the hippocampal CA3 region. Neuropharmacology. 39: 1933-42. PMID 10963737 DOI: 10.1016/S0028-3908(00)00036-8  1
1999 Cobb SR, Manuel NA, Morton RA, Gill CH, Collingridge GL, Davies CH. Regulation of depolarizing GABA(A) receptor-mediated synaptic potentials by synaptic activation of GABA(B) autoreceptors in the rat hippocampus. Neuropharmacology. 38: 1723-32. PMID 10587088 DOI: 10.1016/S0028-3908(99)00158-6  1
1999 Cobb SR, Bulters DO, Suchak S, Riedel G, Morris RG, Davies CH. Activation of nicotinic acetylcholine receptors patterns network activity in the rodent hippocampus. The Journal of Physiology. 518: 131-40. PMID 10373695 DOI: 10.1111/j.1469-7793.1999.0131r.x  1
1997 Cobb SR, Halasy K, Vida I, Nyiri G, Tamás G, Buhl EH, Somogyi P. Synaptic effects of identified interneurons innervating both interneurons and pyramidal cells in the rat hippocampus. Neuroscience. 79: 629-48. PMID 9219929 DOI: 10.1016/S0306-4522(97)00055-9  1
1996 Halasy K, Cobb SR, Buhl EH, Nyíri G, Somogyi P. Sites of synaptic junctions established by a GABAergic basket cell on an interneuron in the CA1 area of the rat hippocampus. Neurobiology (Budapest, Hungary). 4: 269-70. PMID 9044361  1
1995 Buhl EH, Cobb SR, Halasy K, Somogyi P. Properties of unitary IPSPs evoked by anatomically identified basket cells in the rat hippocampus. The European Journal of Neuroscience. 7: 1989-2004. PMID 8528474 DOI: 10.1111/j.1460-9568.1995.tb00721.x  1
1995 Cobb SR, Buhl EH, Halasy K, Paulsen O, Somogyi P. Synchronization of neuronal activity in hippocampus by individual GABAergic interneurons. Nature. 378: 75-8. PMID 7477292 DOI: 10.1038/378075a0  1
1989 Matthay KK, Abai AM, Cobb S, Hong K, Papahadjopoulos D, Straubinger RM. Role of ligand in antibody-directed endocytosis of liposomes by human T-leukemia cells. Cancer Research. 49: 4879-86. PMID 2788031  1
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