Marc E. Lenburg, Ph.D. - Publications

Affiliations: 
2000 University of California, San Francisco, San Francisco, CA 
Area:
signal transduction, transcriptional regulation

151 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Menon AA, Lee M, Ke X, Putman RK, Hino T, Rose JA, Duan F, Ash SY, Cho MH, O'Connor GT, Dupuis J, Hatabu H, Lenburg ME, Billatos ES, Hunninghake GM. Bronchial epithelial gene expression and interstitial lung abnormalities. Respiratory Research. 24: 245. PMID 37817229 DOI: 10.1186/s12931-023-02536-w  0.366
2023 Yanagawa J, Tran LM, Salehi-Rad R, Lim RJ, Dumitras C, Fung E, Wallace WD, Prosper AE, Fishbein G, Shea C, Hong R, Kahangi B, Deng JJ, Gower AC, Liu B, ... ... Lenburg ME, et al. Single-cell characterization of pulmonary nodules implicates suppression of immunosurveillance across early stages of lung adenocarcinoma. Cancer Research. PMID 37477508 DOI: 10.1158/0008-5472.CAN-23-0128  0.359
2022 Xu K, Shi X, Husted C, Hong R, Wang Y, Ning B, Sullivan TB, Rieger-Christ KM, Duan F, Marques H, Gower AC, Xiao X, Liu H, Liu G, Duclos G, ... ... Lenburg ME, et al. Smoking modulates different secretory subpopulations expressing SARS-CoV-2 entry genes in the nasal and bronchial airways. Scientific Reports. 12: 18168. PMID 36307504 DOI: 10.1038/s41598-022-17832-6  0.383
2021 Xu K, Shi X, Husted C, Hong R, Wang Y, Ning B, Sullivan T, Rieger-Christ K, Duan F, Marques H, Gower A, Xiao X, Liu H, Liu G, Duclos G, ... ... Lenburg M, et al. Smoking Modulates Different Secretory Subpopulations Expressing SARS-CoV-2 Entry Genes in the Nasal and Bronchial Airways. Research Square. PMID 34729557 DOI: 10.21203/rs.3.rs-887718/v1  0.364
2021 Hicks-Berthet J, Ning B, Federico A, Tilston-Lunel A, Matschulat A, Ai X, Lenburg ME, Beane J, Monti S, Varelas X. Yap/Taz inhibit goblet cell fate to maintain lung epithelial homeostasis. Cell Reports. 36: 109347. PMID 34260916 DOI: 10.1016/j.celrep.2021.109347  0.348
2021 Hicks-Berthet J, Ning B, Federico A, Tilston-Lunel A, Matschulat A, Ai X, Lenburg ME, Beane J, Monti S, Varelas X. Yap/Taz inhibit goblet cell fate to maintain lung epithelial homeostasis. Cell Reports. 36: 109347. PMID 34260916 DOI: 10.1016/j.celrep.2021.109347  0.348
2021 Becker EJ, Faiz A, van den Berge M, Timens W, Hiemstra PS, Clark K, Liu G, Xiao X, Alekseyev YO, O'Connor G, Lam S, Spira A, Lenburg ME, Steiling K. Bronchial gene expression signature associated with rate of subsequent FEV decline in individuals with and at risk of COPD. Thorax. PMID 33972452 DOI: 10.1136/thoraxjnl-2019-214476  0.334
2020 Choi Y, Qu J, Wu S, Hao Y, Zhang J, Ning J, Yang X, Lofaro L, Pankratz DG, Babiarz J, Walsh PS, Billatos E, Lenburg ME, Kennedy GC, McAuliffe J, et al. Improving lung cancer risk stratification leveraging whole transcriptome RNA sequencing and machine learning across multiple cohorts. Bmc Medical Genomics. 13: 151. PMID 33087128 DOI: 10.1186/s12920-020-00782-1  0.401
2020 Billatos E, Ash SY, Duan F, Xu K, Romanoff J, Marques H, Moses E, Han MK, Regan EA, Bowler RP, Mason SE, Doyle TJ, San José Estépar R, Rosas IO, Ross JC, ... ... Lenburg ME, et al. Distinguishing smoking related lung disease phenotypes via imaging and molecular features. Chest. PMID 32946850 DOI: 10.1016/J.Chest.2020.08.2115  0.41
2020 Drizik E, Corbett S, Zheng Y, Vermeulen R, Dai Y, Hu W, Ren D, Duan H, Niu Y, Xu J, Fu W, Meliefste K, Zhou B, Zhang X, Yang J, ... ... Lenburg ME, et al. Transcriptomic changes in the nasal epithelium associated with diesel engine exhaust exposure. Environment International. 137: 105506. PMID 32044442 DOI: 10.1016/J.Envint.2020.105506  0.339
2020 Shi X, Zhang J, Callori S, Campbell J, Fine D, Gesthalter Y, Liu G, Xiao X, Spira A, Lenburg M, Beane J. Abstract 3377: NSCLC subtype-associated molecular and cellular alterations in the normal-appearing bronchial epithelium Cancer Research. 80: 3377-3377. DOI: 10.1158/1538-7445.Am2020-3377  0.546
2019 Duclos GE, Teixeira VH, Autissier P, Gesthalter YB, Reinders-Luinge MA, Terrano R, Dumas YM, Liu G, Mazzilli SA, Brandsma CA, van den Berge M, Janes SM, Timens W, Lenburg ME, Spira A, et al. Characterizing smoking-induced transcriptional heterogeneity in the human bronchial epithelium at single-cell resolution. Science Advances. 5: eaaw3413. PMID 31844660 DOI: 10.1126/Sciadv.Aaw3413  0.396
2019 Corbett SE, Nitzberg M, Moses E, Kleerup E, Wang T, Perdomo C, Perdomo C, Liu G, Zhang S, Liu H, Elashoff DA, Brooks DR, O'Connor GT, Dubinett SM, Spira A, ... Lenburg ME, et al. Gene Expression Alterations in the Bronchial Epithelium of Electronic Cigarette Users. Chest. PMID 31233743 DOI: 10.1016/J.Chest.2019.05.022  0.414
2019 Hijazi K, Malyszko B, Steiling K, Xiao X, Liu G, Alekseyev YO, Dumas YM, Hertsgaard L, Jensen J, Hatsukami D, Brooks DR, O'Connor G, Beane J, Lenburg ME, Spira A. Tobacco-Related Alterations in Airway Gene Expression are Rapidly Reversed Within Weeks Following Smoking-Cessation. Scientific Reports. 9: 6978. PMID 31061400 DOI: 10.1038/S41598-019-43295-3  0.391
2019 Beane JE, Mazzilli SA, Campbell JD, Duclos G, Krysan K, Moy C, Perdomo C, Schaffer M, Liu G, Zhang S, Liu H, Vick J, Dhillon SS, Platero SJ, Dubinett SM, ... ... Lenburg ME, et al. Molecular subtyping reveals immune alterations associated with progression of bronchial premalignant lesions. Nature Communications. 10: 1856. PMID 31015447 DOI: 10.1038/S41467-019-09834-2  0.436
2019 Faiz A, Steiling K, Roffel MP, Postma DS, Spira A, Lenburg ME, Borggrewe M, Eijgenraam TR, Jonker MR, Koppelman GH, Pouwels SD, Liu G, Alekseyev YO, Lam S, Hiemstra PS, et al. Effect of long-term corticosteroid treatment on microRNA and gene-expression profiles in Chronic Obstructive Pulmonary Disease. The European Respiratory Journal. PMID 30846474 DOI: 10.1183/13993003.01202-2018  0.321
2019 Maoz A, Merenstein C, Mazzilli S, Campbell J, Liu G, Zhang S, Dhillon SS, Stevenson C, Reid ME, Lenburg M, Avi S, Beane J. Characterizing the T cell repertoire in lung squamous cell premalignancy and its association with lesion outcome. Journal of Clinical Oncology. 37: 102-102. DOI: 10.1200/Jco.2019.37.8_Suppl.102  0.391
2019 xu f, Tanabe N, Macdonough J, Vasilescu D, Ikezoe K, Kinose D, Ng K, Verleden S, Vanaudenaerde B, Verschakelen J, Cooper J, Lenburg M, Spira A, Ng R, Hogg J. The transition from normal lung anatomy to Fibrosis in IPF European Respiratory Journal. DOI: 10.1183/13993003.Congress-2019.Oa470  0.357
2019 Becker EJ, Faiz A, Berge MVd, Timens W, Hiemstra PS, Liu G, Zhang X, Alekseyev YO, O'Connor GT, Lam S, Spira A, Lenburg ME, Steiling K. A Bronchial Airway Gene Expression Signature of Future Lung Function Decline Is Enriched in XBP1-Regulated Genes American Journal of Respiratory and Critical Care Medicine. 199. DOI: 10.1164/Ajrccm-Conference.2019.199.1_Meetingabstracts.A7234  0.472
2019 Mazzilli SA, Hijazi K, Pihl R, Belkina A, Zhang X, Liu G, Lenburg M, Stevenson C, Spira A, Beane J. Abstract 660: The molecular characterization of a murine lung premalignancy model for lung cancer interception Cancer Research. DOI: 10.1158/1538-7445.Sabcs18-660  0.431
2019 Zhang J, Burks E, Beane J, Sullivan T, Liu G, Dubinett S, Lenburg M, Spira A. Abstract 3530: Gene expression alterations associated with histologic aggressiveness in stage I lung adenocarcinomas Cancer Research. 79: 3530-3530. DOI: 10.1158/1538-7445.Sabcs18-3530  0.44
2019 Hijazi K, Lel J, Billatos E, Moses E, Stevenson CS, Lorenzi MV, Liu G, Campbell JD, Koga Y, Zhang J, Duan F, Marques H, Lenburg ME, Spira AE, Beane J. Abstract 3393: Altered immune response in the transcriptome of patients with lung cancer Cancer Research. DOI: 10.1158/1538-7445.Sabcs18-3393  0.407
2019 Zhang J, Burks E, Sullivan T, Sands J, Regis S, Mckee B, Mckee A, Zhang S, Liu H, Liu G, Dubinett S, Spira A, Beane J, Christ K, Lenburg M. MA15.06 Stage I Lung Adenocarcinoma Gene Expression Associated with Aggressive Histologic Features for Guiding Precision Surgery and Therapy Journal of Thoracic Oncology. 14: S310-S311. DOI: 10.1016/J.Jtho.2019.08.623  0.394
2019 Lamb C, Hospital L, Center M, Ding J, Saberi S, Pankratz D, Babiarz J, Chamberlin J, Bhorade S, Wilde J, Walsh P, Lofaro L, Huang J, Stevenson C, Lenburg M, et al. LUNG CANCER DETECTION VIA WHOLE-TRANSCRIPTOME RNA SEQUENCING OF NASAL EPITHELIUM Chest. 156: A1091-A1092. DOI: 10.1016/J.Chest.2019.08.1005  0.399
2018 Billatos E, Faiz A, Gesthalter YO, LeClerc A, Alekseyev Y, Zhang X, Liu G, Ten Hacken NHT, Heijink I, Timens W, Brandsma CA, Postma DS, van den Berge M, Spira A, Lenburg ME. The Impact of Acute Exposure to Cigarette Smoke on Airway Gene Expression. Physiological Genomics. PMID 29932825 DOI: 10.1152/Physiolgenomics.00092.2017  0.372
2018 Billatos E, Vick JL, Lenburg ME, Spira AE. The Airway Transcriptome as a Biomarker for Early Lung Cancer Detection. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 29463557 DOI: 10.1158/1078-0432.Ccr-16-3187  0.507
2018 Faiz A, Billatos E, Lenburg M, Spira A, Vonk J, Boezen M, Heijink I, Berge MVD. SNPs which influence the transcriptional response to acute smoke exposure are associated with long term lung function decline in smokers European Respiratory Journal. 52. DOI: 10.1183/13993003.Congress-2018.Pa927  0.368
2018 Steiling K, Zhang J, Sands J, Sullivan T, Billatos E, Moses E, Liu G, Lamb C, McKee B, Lenburg M, Spira A, Rieger-Christ K. Abstract A15: Nasal gene expression for the diagnostic evaluation of indeterminate pulmonary nodules within a screening population Clinical Cancer Research. 24. DOI: 10.1158/1557-3265.Aacriaslc18-A15  0.505
2018 Beane JE, Mazzilli S, Tassinari A, Campbell J, Moy C, Schaffer M, Perdomo C, Jenkins D, Pine MB, Liu G, Zhang S, Lin H, Vick J, Johnson E, Platero S, ... ... Lenburg M, et al. Abstract A05: Bronchial premalignant lesions have distinct molecular subtypes associated with future histologic progression Clinical Cancer Research. 24. DOI: 10.1158/1557-3265.Aacriaslc18-A05  0.487
2018 Mazzilli S, Zhang S, Liu G, Lenburg M, Spira A, Beane J. Abstract B18: The carcinogen-induced NTCU model: A preclinical mouse model for lung cancer interception Cancer Research. 78. DOI: 10.1158/1538-7445.Mousemodels17-B18  0.473
2018 Shi X, Duclos G, Campbell J, Gesthalter Y, Autissier P, Dumas YM, Terrano R, Liu G, Lenburg ME, Spira A, Beane J. Abstract 2534: Single-cell RNA sequencing reveals lung cancer-associated alterations in bronchial cell subpopulations in the mainstem bronchus Cancer Research. 78: 2534-2534. DOI: 10.1158/1538-7445.Am2018-2534  0.511
2018 Shi X, Billatos E, Zhang J, Beane J, Moses E, Liu G, Stevenson C, Lenburg ME, Spira A. Abstract 2531: Diagnostic evaluation of indeterminate pulmonary nodules via rna-seq of bronchial epithelium Cancer Research. 78: 2531-2531. DOI: 10.1158/1538-7445.Am2018-2531  0.479
2017 Boudewijn IM, Faiz A, Steiling K, van der Wiel E, Telenga ED, Hoonhorst SJM, Ten Hacken NHT, Brandsma CA, Kerstjens HAM, Timens W, Heijink IH, Jonker MR, de Bruin HG, Sebastiaan Vroegop J, Pasma HR, ... ... Lenburg ME, et al. Nasal gene expression differentiates COPD from controls and overlaps bronchial gene expression. Respiratory Research. 18: 213. PMID 29268739 DOI: 10.1186/S12931-017-0696-5  0.416
2017 Ong J, Timens W, Rajendran V, Algra A, Spira A, Lenburg ME, Campbell JD, van den Berge M, Postma DS, van den Berg A, Kluiver J, Brandsma CA. Identification of transforming growth factor-beta-regulated microRNAs and the microRNA-targetomes in primary lung fibroblasts. Plos One. 12: e0183815. PMID 28910321 DOI: 10.1371/Journal.Pone.0183815  0.353
2017 Pavel AB, Campbell JD, Liu G, Elashoff DA, Dubinett SM, Smith K, Whitney D, Lenburg ME, Spira AE. Alterations in bronchial airway microRNA expression for lung cancer detection. Cancer Prevention Research (Philadelphia, Pa.). PMID 28877936 DOI: 10.1158/1940-6207.Capr-17-0098  0.5
2017 Suzuki M, Sze MA, Campbell JD, Brothers JF, Lenburg ME, McDonough JE, Elliott WM, Cooper JD, Spira A, Hogg JC. The cellular and molecular determinants of emphysematous destruction in COPD. Scientific Reports. 7: 9562. PMID 28842670 DOI: 10.1038/S41598-017-10126-2  0.422
2017 Beane J, Mazzilli SA, Tassinari AM, Liu G, Zhang X, Liu H, Dy Buncio A, Dhillon SS, Platero SJ, Lenburg ME, Reid ME, Lam S, Spira AE. Detecting the Presence and Progression of Premalignant Lung Lesions via Airway Gene Expression. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 28533227 DOI: 10.1158/1078-0432.Ccr-16-2540  0.507
2017 Boudewijn IM, Faiz A, Steiling K, Wiel Evd, Telenga E, Hoonhorst S, Hacken Nt, Brandsma C, Kerstjens H, Timens W, Heijink I, Jonker M, Bruin Hd, Vroegop S, Pasma H, ... ... Lenburg M, et al. A nasal gene expression profile differentiates individuals with and without COPD and overlaps bronchial gene expression European Respiratory Journal. 50. DOI: 10.1183/1393003.Congress-2017.Pa4470  0.429
2017 Ong J, Timens W, Rajendran V, Algra A, Spira A, Lenburg M, Campbell J, Berge Mvd, Postma D, Berg Avd, Kluiver J, Brandsma C. Target gene identification of TGF-beta-induced miR-455-3p and miR-21-3p in lung fibroblasts European Respiratory Journal. 50. DOI: 10.1183/1393003.Congress-2017.Pa1025  0.304
2017 Beane JE, Mazzilli S, Campbell J, Moy C, Schaffer M, Perdomo C, Jenkins D, Liu G, Zhang S, Liu H, Vick J, Johnson E, Platero S, Lenburg M, Reid M, et al. Abstract 5002: Premalignant squamous cell lung carcinoma lesions have distinct molecular subtypes associated with histologic progression Cancer Research. 77: 5002-5002. DOI: 10.1158/1538-7445.Am2017-5002  0.366
2017 Drizik EI, Corbett S, Vermeulen R, Dai Y, Hu W, Lenburg M, Ren D, Duan H, Niu Y, Xu J, Fu W, Meliefste K, Zhou B, Yang J, Ye M, et al. Abstract 4256: Impact of diesel engine exhaust exposure on the airway transcriptome Cancer Research. 77: 4256-4256. DOI: 10.1158/1538-7445.Am2017-4256  0.397
2017 Campbell J, Zhang X, Dhillon SS, Perdomo C, Mazzilli S, Geshalter Y, Liu G, Zhang S, Lin H, Vick J, Moy C, Monti S, Johnson E, Meyerson M, Dubinett S, ... ... Lenburg M, et al. Abstract 3259: The genomic landscape of premalignant lung squamous cell carcinoma lesions Cancer Research. 77: 3259-3259. DOI: 10.1158/1538-7445.Am2017-3259  0.353
2017 Duclos GE, Campbell JD, Gesthalter Y, Autissier P, Dumas YM, Terrano R, Liu G, Lenburg ME, Spira A, Beane J. Abstract 1433: Single cell RNA sequencing reveals smoking-associated alterations in bronchial airway epithelial subpopulations Cancer Research. 77: 1433-1433. DOI: 10.1158/1538-7445.Am2017-1433  0.515
2017 Mazzilli SA, Tassinari A, Xiao X, Liu G, Dhillon S, Johnson C, Reid M, Lenburg M, Spira A, Beane J. Abstract 1252: A pre-clinical model for lung cancer interception: gene expression similarities between human and mouse bronchial premalignant lesions Cancer Research. 77: 1252-1252. DOI: 10.1158/1538-7445.Am2017-1252  0.466
2017 Lee H, Whitten P, Bhadra K, Dotson T, Hogarth D, Benzaquen S, Pritchett M, Gordon J, Bedekar A, Esterle M, Smith K, Bianchi P, Lenburg M, Spira A. Prospective Utility of a Bronchial Genomic Classifier for Lung Cancer Detection: Interim Results From a Multicenter Prospective Registry Chest. 152: A625. DOI: 10.1016/J.Chest.2017.08.658  0.417
2016 Moses E, Wang T, Corbett S, Jackson GR, Drizik E, Perdomo C, Perdomo C, Kleerup E, Brooks D, O'Connor G, Dubinett S, Hayden P, Lenburg ME, Spira A. Molecular impact of electronic cigarette aerosol exposure in human bronchial epithelium. Toxicological Sciences : An Official Journal of the Society of Toxicology. PMID 27701119 DOI: 10.1093/Toxsci/Kfw198  0.402
2016 Lam S, Mandrekar SJ, Gesthalter Y, Allen Ziegler KL, Seisler DK, Midthun DE, Mao JT, Aubry MC, McWilliams A, Sin DD, Shaipanich T, Liu G, Johnson E, Bild AH, Lenburg ME, et al. A Randomized Phase IIb Trial of myo-Inositol in Smokers with Bronchial Dysplasia. Cancer Prevention Research (Philadelphia, Pa.). PMID 27658890 DOI: 10.1158/1940-6207.Capr-15-0254  0.351
2016 Hu Z, Mao JH, Curtis C, Huang G, Gu S, Heiser L, Lenburg ME, Korkola JE, Bayani N, Samarajiwa S, Seoane JA, A Dane M, Esch A, Feiler HS, Wang NJ, et al. Genome co-amplification upregulates a mitotic gene network activity that predicts outcome and response to mitotic protein inhibitors in breast cancer. Breast Cancer Research : Bcr. 18: 70. PMID 27368372 DOI: 10.1186/S13058-016-0728-Y  0.333
2016 Vachani A, Whitney DH, Parsons EC, Lenburg M, Ferguson JS, Silvestri GA, Spira A. Clinical Utility of a Bronchial Genomic Classifier in Patients with Suspected Lung Cancer. Chest. PMID 26896702 DOI: 10.1016/J.Chest.2016.02.636  0.441
2016 Imkamp K, Faiz A, Wiel Evd, Boudewijn I, Koppelman G, Brandsma C, Kerstjens H, Timens W, Vroegop S, Pasma H, Boersma W, Wielders P, Elshout Fvd, Mansour K, Steiling K, ... ... Lenburg M, et al. Effects of ICS/LABA treatment on hyperinflation and genome wide gene-expression in upper airway epithelium in severe COPD European Respiratory Journal. 48. DOI: 10.1183/13993003.Congress-2016.Pa1203  0.33
2016 Mazzilli SA, Tassinari A, Gethalter Y, Lui G, Pine M, Lam S, Reid M, Platero S, Lenburg M, Spira A, Beane J. Abstract 896: The airway field of injury reflects gene expression changes associated with the presence of lung squamous premalignant lesions Cancer Research. 76: 896-896. DOI: 10.1158/1538-7445.Am2016-896  0.416
2016 Campbell JD, Perdomo C, Mazzilli S, Geshalter Y, Dhillon SS, Liu G, Zhang S, Lin H, Vick J, Moy C, Johnson E, Meyerson M, Platero S, Lenburg M, Reid M, et al. Abstract 895: Genomic characterization of premalignant lung squamous cell carcinoma lesions Cancer Research. 76: 895-895. DOI: 10.1158/1538-7445.Am2016-895  0.473
2016 Moses E, Wang T, Jackson GR, Corbett S, Drizik E, Brooks D, O’Connor G, Perdomo C, Dubinett S, Hayden P, Lenburg ME, Spira A. Abstract 4502: Molecular impact of in vitro exposure to electronic cigarette vapor in human bronchial epithelium Cancer Research. 76: 4502-4502. DOI: 10.1158/1538-7445.Am2016-4502  0.391
2016 Pavel AB, Campbell J, Liu G, Zhang S, Liu H, Xiao J, Porta K, Whitney D, Dubinett S, Elashoff D, Lenburg M, Spira A. Abstract 1954: microRNA expression in bronchial epithelium for lung cancer detection Cancer Research. 76: 1954-1954. DOI: 10.1158/1538-7445.Am2016-1954  0.453
2016 Becker E, Lam S, van den Berge M, Liu G, Zhang X, Alekseyev Y, Spira A, Lenburg M, Steiling K. Predicting Lung Function Decline in COPD Using Bronchial Airway Gene Expression Chest. 150: 912A. DOI: 10.1016/J.Chest.2016.08.1012  0.457
2015 Wang TW, Vermeulen RC, Hu W, Liu G, Xiao X, Alekseyev Y, Xu J, Reiss B, Steiling K, Downward GS, Silverman DT, Wei F, Wu G, Li J, Lenburg ME, et al. Gene-expression profiling of buccal epithelium among nonsmoking women exposed to household air pollution from smoky coal. Carcinogenesis. PMID 26468118 DOI: 10.1093/Carcin/Bgv150  0.446
2015 Silvestri GA, Vachani A, Whitney D, Elashoff M, Porta Smith K, Ferguson JS, Parsons E, Mitra N, Brody J, Lenburg ME, Spira A. A Bronchial Genomic Classifier for the Diagnostic Evaluation of Lung Cancer. The New England Journal of Medicine. 373: 243-51. PMID 25981554 DOI: 10.1056/Nejmoa1504601  0.459
2015 Sze MA, Dimitriu PA, Suzuki M, McDonough JE, Campbell JD, Brothers JF, Erb-Downward JR, Huffnagle GB, Hayashi S, Elliott WM, Cooper J, Sin DD, Lenburg ME, Spira A, Mohn WW, et al. The Host Response to the Lung Microbiome in Chronic Obstructive Pulmonary Disease. American Journal of Respiratory and Critical Care Medicine. PMID 25945594 DOI: 10.1164/Rccm.201502-0223Oc  0.401
2015 Whitney DH, Elashoff MR, Porta-Smith K, Gower AC, Vachani A, Ferguson JS, Silvestri GA, Brody JS, Lenburg ME, Spira A. Derivation of a bronchial genomic classifier for lung cancer in a prospective study of patients undergoing diagnostic bronchoscopy. Bmc Medical Genomics. 8: 18. PMID 25944280 DOI: 10.1186/S12920-015-0091-3  0.506
2015 Christenson SA, Steiling K, van den Berge M, Hijazi K, Hiemstra PS, Postma DS, Lenburg ME, Spira A, Woodruff PG. Asthma-COPD overlap. Clinical relevance of genomic signatures of type 2 inflammation in chronic obstructive pulmonary disease. American Journal of Respiratory and Critical Care Medicine. 191: 758-66. PMID 25611785 DOI: 10.1164/Rccm.201408-1458Oc  0.339
2015 Campbell JD, Liu G, Luo L, Xiao J, Gerrein J, Juan-Guardela B, Tedrow J, Alekseyev YO, Yang IV, Correll M, Geraci M, Quackenbush J, Sciurba F, Schwartz DA, Kaminski N, ... ... Lenburg ME, et al. Assessment of microRNA differential expression and detection in multiplexed small RNA sequencing data. Rna (New York, N.Y.). 21: 164-71. PMID 25519487 DOI: 10.1261/Rna.046060.114  0.316
2015 Billatos E, Gesthalter Y, ten Hacken N, Postma D, Heijink I, Timens W, Brandsma C, Faiz A, Berge M, Lenburg M, Spira A. The Impact of Acute Smoking on Airway Gene-Expression Chest. 148: 746A. DOI: 10.1378/Chest.2280491  0.398
2015 Vachani A, Silvestri G, Whitney D, Ferguson J, Porta K, Parsons E, Brody J, Lenburg M, Spira A. Prospective Validation of a Bronchial Genomic Classifier for Lung Cancer in Patients Undergoing Diagnostic Bronchoscopy: The AEGIS Trials Chest. 148: 544A. DOI: 10.1378/Chest.2280365  0.406
2015 Faiz A, Borggrewe M, Postma D, Steiling K, Spira A, Lenburg M, Jonker M, Koppelman G, Hiemstra P, Sterk P, Timens W, Brandsma C, Berge MVd, Heijink I. MiR-320d: A novel anti-inflammatory miRNA up regulated by corticosteroids European Respiratory Journal. 46. DOI: 10.1183/13993003.Congress-2015.Oa2927  0.329
2015 Park SJ, Walser TC, Tran LM, Perdomo C, Wang T, Hong L, Pagano PC, Liclican EL, Larsen JE, Krysan K, Fishbein MC, Minna JD, Lenburg ME, Avrum S, Dubinett S. Abstract B22: The role of e-cigarette exposure on pulmonary epithelial cell transformation Cancer Prevention Research. 8. DOI: 10.1158/1940-6215.Prev-14-B22  0.475
2015 Mazzilli SA, Liu G, Zhang X, Si H, Lam S, Lenburg M, Spira A, Beane JE. Abstract A11: Airway gene expression indicates an increase in oxidative phosphorylation in the field of injury of individuals with premalignant lesions Cancer Prevention Research. 8. DOI: 10.1158/1940-6215.Prev-14-A11  0.454
2015 Perez-Rogers JF, Gerrein J, Anderlind C, Kusko RL, Campbell JD, Wang TW, Porta K, Whitney D, Spira A, Lenburg M. Abstract A1-66: Leveraging Gene Expression in the Bronchial Airway to Develop a Nasal Biomarker for Early Detection of Lung Cancer Cancer Research. 75. DOI: 10.1158/1538-7445.Transcagen-A1-66  0.533
2015 Tassinari A, Zhang B, Steiling K, Whitney D, Porta K, Lam S, Lenburg M, Spira A, Beane J. Abstract B1-17: Airway gene-coexpression network rewiring in the presence of bronchial dysplasia and lung cancer Cancer Research. 75. DOI: 10.1158/1538-7445.Compsysbio-B1-17  0.445
2015 Pavel AB, Campbell JD, Liu G, Zhang S, Liu H, Luo L, Xiao J, Porta K, Whitney D, Dubinett S, Elashoff D, Lenburg ME, Spira A. Abstract 3077: Dysregulation of microRNA-mRNA regulatory networks in the bronchial airway epithelium of smokers with lung cancer Cancer Research. 75: 3077-3077. DOI: 10.1158/1538-7445.Am2015-3077  0.524
2015 Beane JE, Campbell J, Moy C, Perdomo C, Schaffer M, Mazzilli S, Geshalter Y, Kantrowitz J, Zhang L, Jenkins D, Pine MB, Dhillon S, Liu G, Liu H, Zhang S, ... ... Lenburg M, et al. Abstract 2878: Development of the pre-cancer genome atlas (PCGA) for squamous cell lung carcinoma Cancer Research. 75: 2878-2878. DOI: 10.1158/1538-7445.Am2015-2878  0.498
2015 Perez-Rogers J, Gerrein J, Anderlind C, Xiao X, Liu H, Kusko R, Campbell J, Wang T, Alekseyev Y, Liu G, Porta K, Whitney D, Spira A, Lenburg M. Abstract 1574: Leveraging bronchial airway gene expression to develop a nasal biomarker for lung cancer detection Cancer Research. 75: 1574-1574. DOI: 10.1158/1538-7445.Am2015-1574  0.533
2014 Lamontagne M, Timens W, Hao K, Bossé Y, Laviolette M, Steiling K, Campbell JD, Couture C, Conti M, Sherwood K, Hogg JC, Brandsma CA, van den Berge M, Sandford A, Lam S, ... Lenburg ME, et al. Genetic regulation of gene expression in the lung identifies CST3 and CD22 as potential causal genes for airflow obstruction. Thorax. 69: 997-1004. PMID 25182044 DOI: 10.1136/Thoraxjnl-2014-205630  0.461
2014 Ooi AT, Gower AC, Zhang KX, Vick JL, Hong L, Nagao B, Wallace WD, Elashoff DA, Walser TC, Dubinett SM, Pellegrini M, Lenburg ME, Spira A, Gomperts BN. Molecular profiling of premalignant lesions in lung squamous cell carcinomas identifies mechanisms involved in stepwise carcinogenesis. Cancer Prevention Research (Philadelphia, Pa.). 7: 487-95. PMID 24618292 DOI: 10.1158/1940-6207.Capr-13-0372  0.443
2014 Wolf DM, Lenburg ME, Yau C, Boudreau A, van 't Veer LJ. Gene co-expression modules as clinically relevant hallmarks of breast cancer diversity. Plos One. 9: e88309. PMID 24516633 DOI: 10.1371/Journal.Pone.0088309  0.398
2014 Vucic EA, Chari R, Thu KL, Wilson IM, Cotton AM, Kennett JY, Zhang M, Lonergan KM, Steiling K, Brown CJ, McWilliams A, Ohtani K, Lenburg ME, Sin DD, Spira A, et al. DNA methylation is globally disrupted and associated with expression changes in chronic obstructive pulmonary disease small airways. American Journal of Respiratory Cell and Molecular Biology. 50: 912-22. PMID 24298892 DOI: 10.1165/Rcmb.2013-0304Oc  0.404
2014 van den Berge M, Steiling K, Timens W, Hiemstra PS, Sterk PJ, Heijink IH, Liu G, Alekseyev YO, Lenburg ME, Spira A, Postma DS. Airway gene expression in COPD is dynamic with inhaled corticosteroid treatment and reflects biological pathways associated with disease activity. Thorax. 69: 14-23. PMID 23925644 DOI: 10.1136/Thoraxjnl-2012-202878  0.386
2014 Jiwani A, Maple E, Schnall M, Mahon I, Apgar C, Browning R, More K, Morris M, Parrish J, Atwood C, Battaile J, Garshick E, Gatsonis C, Goldstein R, Kieth R, ... Lenburg M, et al. Detection and Validation of Molecular Biomarkers for the Early Detection of Lung Cancer Among Military and Veteran Populations: The DECAMP Consortium Chest. 146: 590A. DOI: 10.1378/Chest.1993874  0.376
2014 Park SJ, Walser TC, Perdomo C, Wang T, Hong L, Pagano PC, Liclican EL, Krysan K, Larsen JE, Fishbein MC, Minna JD, Lenburg ME, Spira A, Dubinett SM. Abstract 932: The impact of e-cigarette exposure on pulmonary epithelium gene expression and transformation Cancer Research. 74: 932-932. DOI: 10.1158/1538-7445.Am2014-932  0.485
2014 Kusko R, Garrison C, Wang T, Campbell J, Perez-Rogers J, Luo L, Beane J, Liu G, Kadara H, Belinsky S, Lenburg ME, Spira A. Abstract 3554: Gene and miRNA expression networks specific to never smoker lung adenocarcinoma Cancer Research. 74: 3554-3554. DOI: 10.1158/1538-7445.Am2014-3554  0.461
2014 Kusko R, Anderlind C, Wang G, Zhang S, Wallace WD, Wasler T, Ebright M, Garcia MM, Eisenberg R, Lee G, Liu G, Elashoff D, Kalhor N, Moran C, Mehran R, ... ... Lenburg M, et al. Abstract 2352: Mapping the airway-wide molecular field of injury in smokers with lung cancer Cancer Research. 74: 2352-2352. DOI: 10.1158/1538-7445.Am2014-2352  0.529
2014 Pavel A, Campbell J, Liu G, Zhang S, Liu H, Dubinett S, Elashoff D, Porta K, Whitney D, Lenburg M, Spira A. Abstract 1485: Biomarker development for lung cancer diagnosis using integrative microRNA and gene expression networks Cancer Research. 74: 1485-1485. DOI: 10.1158/1538-7445.Am2014-1485  0.441
2014 Tassinari A, Whitney D, Porta K, Lenburg M, Spira A, Beane J. Abstract 1414: Race-associated variation in the airway transcriptome response to cigarette smoke Cancer Research. 74: 1414-1414. DOI: 10.1158/1538-7445.Am2014-1414  0.472
2013 Christenson SA, Brandsma CA, Campbell JD, Knight DA, Pechkovsky DV, Hogg JC, Timens W, Postma DS, Lenburg M, Spira A. miR-638 regulates gene expression networks associated with emphysematous lung destruction. Genome Medicine. 5: 114. PMID 24380442 DOI: 10.1186/Gm519  0.438
2013 Steiling K, Lenburg ME, Spira A. Personalized management of chronic obstructive pulmonary disease via transcriptomic profiling of the airway and lung. Annals of the American Thoracic Society. 10: S190-6. PMID 24313772 DOI: 10.1513/Annalsats.201306-190Aw  0.385
2013 Perdomo C, Campbell JD, Gerrein J, Tellez CS, Garrison CB, Walser TC, Drizik E, Si H, Gower AC, Vick J, Anderlind C, Jackson GR, Mankus C, Schembri F, O'Hara C, ... ... Lenburg ME, et al. MicroRNA 4423 is a primate-specific regulator of airway epithelial cell differentiation and lung carcinogenesis. Proceedings of the National Academy of Sciences of the United States of America. 110: 18946-51. PMID 24158479 DOI: 10.1073/Pnas.1220319110  0.484
2013 Zhang X, Lenburg ME, Spira A. Comparison of nasal epithelial smoking-induced gene expression on Affymetrix Exon 1.0 and Gene 1.0 ST arrays. Thescientificworldjournal. 2013: 951416. PMID 23476154 DOI: 10.1155/2013/951416  0.41
2013 Steiling K, van den Berge M, Hijazi K, Florido R, Campbell J, Liu G, Xiao J, Zhang X, Duclos G, Drizik E, Si H, Perdomo C, Dumont C, Coxson HO, Alekseyev YO, ... ... Lenburg ME, et al. A dynamic bronchial airway gene expression signature of chronic obstructive pulmonary disease and lung function impairment. American Journal of Respiratory and Critical Care Medicine. 187: 933-42. PMID 23471465 DOI: 10.1164/Rccm.201208-1449Oc  0.419
2013 Park SJ, Walser TC, Perdomo C, Pagano PP, Brass D, Liclican EL, Krysan K, Lenburg ME, Spira A, Dubinett SM. Abstract C58: The gene expression and functional impact of E-cigarette exposure on pulmonary epithelial transformation Cancer Prevention Research. 6. DOI: 10.1158/1940-6215.Prev-13-C58  0.408
2013 Wolf DM, Yau C, Boudreau A, Esserman L, Veer LV‘, Lenburg M. Abstract 5221: Co-expression modules as hallmarks of breast cancer survival and response. Cancer Research. 73: 5221-5221. DOI: 10.1158/1538-7445.Am2013-5221  0.407
2013 Hijazi K, Malyszko B, Steiling K, Zhang X, Liu G, Alekseyev Y, Xiao J, Dumas M, Hertsgaard L, Jenson J, Rohde C, Isaksson R, Hatsukami D, Hecht S, Brooks D, ... Lenburg M, et al. Abstract 4030: Nasal gene expression reflects the physiologic response to alternate tobacco products. Cancer Research. 73: 4030-4030. DOI: 10.1158/1538-7445.Am2013-4030  0.373
2013 Wang T, Campbell J, Kusko R, Luo L, Tellez C, Liu G, Xiao J, Lenburg M, Belinsky S, Spira A. Abstract 1948: Shared and distinct microRNA-expression alterations in lung adenocarcinoma from smokers vs. nonsmokers. Cancer Research. 73: 1948-1948. DOI: 10.1158/1538-7445.Am2013-1948  0.42
2013 Wang TW, Lan Q, Krystyna B, Rothman N, Florido R, Hu W, Steiling K, Liu G, Xiao J, Alekseyev Y, Xu J, Wei F, Hosgood HD, Reiss B, Downward G, ... Lenburg M, et al. Abstract 112: Transcriptomic changes in the oral mucosal epithelium reflect the physiologic response to indoor burning of solid fuels. Cancer Research. 73: 112-112. DOI: 10.1158/1538-7445.Am2013-112  0.457
2013 Ooi AT, Gower A, Zhang K, Vick J, Hong L, Fishbein M, Nagao B, Wallace WD, Elashoff D, Lenburg M, Dubinett S, Spira A, Gomperts B. Abstract 1063: Examining early events in carcinogenesis by profiling premalignant lesions in the airways of patients with lung squamous cell carcinomas. Cancer Research. 73: 1063-1063. DOI: 10.1158/1538-7445.Am2013-1063  0.495
2012 Beane J, Cheng L, Soldi R, Zhang X, Liu G, Anderlind C, Lenburg ME, Spira A, Bild AH. SIRT1 pathway dysregulation in the smoke-exposed airway epithelium and lung tumor tissue. Cancer Research. 72: 5702-11. PMID 22986747 DOI: 10.1158/0008-5472.Can-12-1043  0.5
2012 Campbell JD, McDonough JE, Zeskind JE, Hackett TL, Pechkovsky DV, Brandsma CA, Suzuki M, Gosselink JV, Liu G, Alekseyev YO, Xiao J, Zhang X, Hayashi S, Cooper JD, Timens W, ... ... Lenburg ME, et al. A gene expression signature of emphysema-related lung destruction and its reversal by the tripeptide GHK. Genome Medicine. 4: 67. PMID 22937864 DOI: 10.1186/Gm367  0.422
2012 Lee SY, Meier R, Furuta S, Lenburg ME, Kenny PA, Xu R, Bissell MJ. FAM83A confers EGFR-TKI resistance in breast cancer cells and in mice. The Journal of Clinical Investigation. 122: 3211-20. PMID 22886303 DOI: 10.1172/Jci60498  0.346
2012 Horiuchi D, Kusdra L, Huskey NE, Chandriani S, Lenburg ME, Gonzalez-Angulo AM, Creasman KJ, Bazarov AV, Smyth JW, Davis SE, Yaswen P, Mills GB, Esserman LJ, Goga A. MYC pathway activation in triple-negative breast cancer is synthetic lethal with CDK inhibition. The Journal of Experimental Medicine. 209: 679-96. PMID 22430491 DOI: 10.1084/Jem.20111512  0.331
2012 Esserman LJ, Berry DA, Cheang MC, Yau C, Perou CM, Carey L, DeMichele A, Gray JW, Conway-Dorsey K, Lenburg ME, Buxton MB, Davis SE, van't Veer LJ, Hudis C, Chin K, et al. Chemotherapy response and recurrence-free survival in neoadjuvant breast cancer depends on biomarker profiles: results from the I-SPY 1 TRIAL (CALGB 150007/150012; ACRIN 6657). Breast Cancer Research and Treatment. 132: 1049-62. PMID 22198468 DOI: 10.1007/S10549-011-1895-2  0.332
2012 Whitney D, Luo J, Porta K, Lenburg M, Brody J, Ernst A, Vachani A, Ferguson J, Silvestri G, Spira A. Bronchial Airway Gene-Expression Testing Improves the Diagnostic Yield of Bronchoscopy for Lung Cancer: Results of the AEGIS Trial Chest. 142: 1025A. DOI: 10.1378/Chest.1450411  0.477
2012 Campbell JD, Luo L, Liu G, Xiao J, Gerrein J, Guardela BJ, Tedrow J, Aleksyev YO, Yang IV, Correll M, Geraci M, Quackenbush J, Sciurba F, Schwartz DA, Kaminski N, ... Lenburg ME, et al. Characterizing the small RNA transcriptome associated with COPD and ILD using next-generation sequencing Bmc Proceedings. 6. DOI: 10.1186/1753-6561-6-S6-P6  0.384
2012 Brothers J, Kusko R, Liu G, Luo L, Guardela BJ, Tedrow J, Alekesyev Y, Yang IV, Correll M, Geraci M, Quackenbush J, Sciurba F, Sebastiani P, Lenburg M, Kaminski N, et al. Moving beyond gene expression: identification of lung-disease-associated novel transcripts and alternative splicing by RNA sequencing Bmc Proceedings. 6. DOI: 10.1186/1753-6561-6-S6-P4  0.42
2012 Wang TW, Campbell JD, Luo L, Liu G, Xiao J, Lenburg ME, Belinsky SA, Spira A. Deep sequencing of the microRNA transcriptome in current, former, and never smokers with lung adenocarcinoma Bmc Proceedings. 6. DOI: 10.1186/1753-6561-6-S6-P38  0.459
2012 Kusko RL, Brothers J, Liu G, Luo L, Guardela BJ, Tedrow J, Aleksyev Y, Yang IV, Correll M, Geraci M, Quackenbush J, Sciurba F, Lenburg M, Schwartz DA, Beane J, et al. Comprehensive genomic profiling of the lung transcriptome in emphysema and idiopathic pulmonary fibrosis using RNA-Seq Bmc Proceedings. 6. DOI: 10.1186/1753-6561-6-S6-P21  0.439
2012 Hijazi K, Malyszko B, Zhang X, Liu G, Alekseyev Y, Dumas Y, Hertsgaard L, Jenson J, Rohde C, Hatsukami DK, Hecht SS, Brooks DR, O'Connor G, Lenburg M, Steiling K, et al. Abstract B07: Nasal epithelial gene expression profiles reflect dynamic biological response to smoking cessation Cancer Prevention Research. 5: B07-B07. DOI: 10.1158/1940-6207.Prev-12-B07  0.406
2012 Beane JE, Hijazi K, Steiling K, Liu G, Zhang S, Lam S, Lenburg M. Abstract A27: Airway molecular alterations associated with premalignant lesion progression and lung cancer development Cancer Prevention Research. 5: A27-A27. DOI: 10.1158/1940-6207.Prev-12-A27  0.524
2012 Perdomo C, Campbell J, Gerrein J, Tellez C, Gower A, Vick J, Garrison C, Anderlind C, Jackson GR, Schembri F, Gomperts BN, Hayden P, Belinsky SA, Lenburg ME, Spira A. Abstract 3173: Identification of miR-4423 as a primate-specific microRNA highly expressed in airway epithelium and associated with lung cancer Cancer Research. 72: 3173-3173. DOI: 10.1158/1538-7445.Am2012-3173  0.504
2012 Campbell JD, Luo L, Xiao J, Liu G, Aleksyev Y, Elashoff D, Dubinett SM, Lenburg ME, Spira A. Abstract 3154: Sequencing of the small RNA transcriptome in cytologically normal bronchial airway epithelium of smokers with and without lung cancer Cancer Research. 72: 3154-3154. DOI: 10.1158/1538-7445.Am2012-3154  0.52
2012 Beane JE, Hijazi K, Liu G, Zhang X, Xiao J, Lam S, Lenburg M, Spira A. Abstract 1607: Airway gene expression alterations associated with lung cancer chemoprevention using green tea extract Cancer Research. 72: 1607-1607. DOI: 10.1158/1538-7445.Am2012-1607  0.491
2011 Gower AC, Spira A, Lenburg ME. Discovering biological connections between experimental conditions based on common patterns of differential gene expression. Bmc Bioinformatics. 12: 381. PMID 21951600 DOI: 10.1186/1471-2105-12-381  0.404
2011 Beane J, Vick J, Schembri F, Anderlind C, Gower A, Campbell J, Luo L, Zhang XH, Xiao J, Alekseyev YO, Wang S, Levy S, Massion PP, Lenburg M, Spira A. Characterizing the impact of smoking and lung cancer on the airway transcriptome using RNA-Seq. Cancer Prevention Research (Philadelphia, Pa.). 4: 803-17. PMID 21636547 DOI: 10.1158/1940-6207.Capr-11-0212  0.492
2011 Gower AC, Steiling K, Brothers JF, Lenburg ME, Spira A. Transcriptomic studies of the airway field of injury associated with smoking-related lung disease. Proceedings of the American Thoracic Society. 8: 173-9. PMID 21543797 DOI: 10.1513/pats.201011-066MS  0.352
2011 Campbell JD, Spira A, Lenburg ME. Applying gene expression microarrays to pulmonary disease. Respirology (Carlton, Vic.). 16: 407-18. PMID 21299687 DOI: 10.1111/J.1440-1843.2011.01942.X  0.407
2011 Boelens MC, Gustafson AM, Postma DS, Kok K, van der Vries G, van der Vlies P, Spira A, Lenburg ME, Geerlings M, Sietsma H, Timens W, van den Berg A, Groen HJ. A chronic obstructive pulmonary disease related signature in squamous cell lung cancer. Lung Cancer (Amsterdam, Netherlands). 72: 177-83. PMID 20832896 DOI: 10.1016/J.Lungcan.2010.08.014  0.426
2011 Wolf D, Lenburg M, Yau C, Boudreau A, Esserman L, Hylton N, Veer LV'. Abstract LB-311: Combinatorial logic over breast cancer control modules predicts survival and chemotherapy response of ISPY1 breast cancer patients (CALGB 150007/150012; ACRIN 6657) Cancer Research. 71. DOI: 10.1158/1538-7445.Am2011-Lb-311  0.367
2011 Gerrein J, Perdomo C, Campbell JD, Vick J, Gower A, Anderlind C, Schembri F, Lenburg M, Spira A. Abstract 3989: Discovery of a novel airway microRNA associated with lung cancer using next generation sequencing Cellular and Molecular Biology. 71: 3989-3989. DOI: 10.1158/1538-7445.Am2011-3989  0.437
2010 Ooi AT, Mah V, Nickerson DW, Gilbert JL, Ha VL, Hegab AE, Horvath S, Alavi M, Maresh EL, Chia D, Gower AC, Lenburg ME, Spira A, Solis LM, Wistuba II, et al. Presence of a putative tumor-initiating progenitor cell population predicts poor prognosis in smokers with non-small cell lung cancer. Cancer Research. 70: 6639-48. PMID 20710044 DOI: 10.1158/0008-5472.Can-10-0455  0.45
2010 Blick T, Hugo H, Widodo E, Waltham M, Pinto C, Mani SA, Weinberg RA, Neve RM, Lenburg ME, Thompson EW. Epithelial mesenchymal transition traits in human breast cancer cell lines parallel the CD44(hi/)CD24 (lo/-) stem cell phenotype in human breast cancer. Journal of Mammary Gland Biology and Neoplasia. 15: 235-52. PMID 20521089 DOI: 10.1007/S10911-010-9175-Z  0.341
2010 Gustafson AM, Soldi R, Anderlind C, Scholand MB, Qian J, Zhang X, Cooper K, Walker D, McWilliams A, Liu G, Szabo E, Brody J, Massion PP, Lenburg ME, Lam S, et al. Airway PI3K pathway activation is an early and reversible event in lung cancer development. Science Translational Medicine. 2: 26ra25. PMID 20375364 DOI: 10.1126/Scitranslmed.3000251  0.478
2010 Hu Z, Huang G, Sadanandam A, Gu S, Lenburg ME, Pai M, Bayani N, Blakely EA, Gray JW, Mao JH. The expression level of HJURP has an independent prognostic impact and predicts the sensitivity to radiotherapy in breast cancer. Breast Cancer Research : Bcr. 12: R18. PMID 20211017 DOI: 10.1186/Bcr2487  0.36
2010 Salisbury Palomares KT, Gerstenfeld LC, Wigner NA, Lenburg ME, Einhorn TA, Morgan EF. Transcriptional profiling and biochemical analysis of mechanically induced cartilaginous tissues in a rat model. Arthritis and Rheumatism. 62: 1108-18. PMID 20131271 DOI: 10.1002/Art.27343  0.31
2010 Papageorgis P, Lambert AW, Ozturk S, Gao F, Pan H, Manne U, Alekseyev YO, Thiagalingam A, Abdolmaleky HM, Lenburg M, Thiagalingam S. Smad signaling is required to maintain epigenetic silencing during breast cancer progression. Cancer Research. 70: 968-78. PMID 20086175 DOI: 10.1158/0008-5472.Can-09-1872  0.357
2010 Zhang X, Sebastiani P, Liu G, Schembri F, Zhang X, Dumas YM, Langer EM, Alekseyev Y, O'Connor GT, Brooks DR, Lenburg ME, Spira A. Similarities and differences between smoking-related gene expression in nasal and bronchial epithelium. Physiological Genomics. 41: 1-8. PMID 19952278 DOI: 10.1152/Physiolgenomics.00167.2009  0.434
2010 Wulfkuhle JD, Lenburg ME, Pierobon M, Illi J, Zhu J, DeMichele A, Espina VA, Liotta LA, Esserman L, Petricoin E, Investigators I. Protein signal pathway mapping of human breast cancer from I-SPY: Correlations with response and genomic subtyping. Journal of Clinical Oncology. 28: 10512-10512. DOI: 10.1200/Jco.2010.28.15_Suppl.10512  0.326
2010 Ooi AT, Mah VH, Nickerson DW, Gilbert JL, Ha VL, Hegab AE, Horvath S, Alavi M, Maresh E, Chia D, Gower AC, Lenburg ME, Spira A, Walser T, Wallace WD, et al. Abstract 4299: Poor prognosis in smokers with non-small cell lung cancer correlates with the presence of a reparative progenitor cell population Cancer Research. 70: 4299-4299. DOI: 10.1158/1538-7445.Am10-4299  0.428
2010 Beane J, Gerrein J, Vick J, Gindin Y, Anderlind C, Levy S, Massion P, Schembri F, Lenburg M, Spira A. Abstract 1987: RNA-seq of the bronchial airway transcriptome identifies novel gene and microRNA expression changes associated with smoking and lung cancer Cancer Research. 70: 1987-1987. DOI: 10.1158/1538-7445.Am10-1987  0.493
2010 Gibb WJ, Collisson E, Korkola J, Heiser L, Sadanandam A, Kuo W, Hu Z, Mao J, Wang N, Bayani N, Billig J, Ziyad S, Lewis S, Feiler H, Jakkula L, ... ... Lenburg M, et al. Abstract 1979: Algebraic factorization of gene expression profiles reveals subtype-specific drug sensitivities among 54 breast cancer cell lines Cancer Research. 70: 1979-1979. DOI: 10.1158/1538-7445.Am10-1979  0.346
2010 Goga A, Horiuchi D, Kusdra L, Chandriani S, Lenburg M, Gonzalez-Angulo A, Huskey N, Creasman K, Davis S, Mills G, Esserman L. Abstract S5-4: Synthetic-Lethality of Triple-Negative Breast Cancers Via the MYC Oncogene Pathway Cancer Research. 70. DOI: 10.1158/0008-5472.Sabcs10-S5-4  0.357
2009 Steiling K, Kadar AY, Bergerat A, Flanigon J, Sridhar S, Shah V, Ahmad QR, Brody JS, Lenburg ME, Steffen M, Spira A. Comparison of proteomic and transcriptomic profiles in the bronchial airway epithelium of current and never smokers. Plos One. 4: e5043. PMID 19357784 DOI: 10.1371/Journal.Pone.0005043  0.384
2009 Zhu J, Sanborn JZ, Benz S, Szeto C, Hsu F, Kuhn RM, Karolchik D, Archie J, Lenburg ME, Esserman LJ, Kent WJ, Haussler D, Wang T. The UCSC Cancer Genomics Browser. Nature Methods. 6: 239-40. PMID 19333237 DOI: 10.1038/Nmeth0409-239  0.318
2009 Schembri F, Sridhar S, Perdomo C, Gustafson AM, Zhang X, Ergun A, Lu J, Liu G, Zhang X, Bowers J, Vaziri C, Ott K, Sensinger K, Collins JJ, Brody JS, ... ... Lenburg ME, et al. MicroRNAs as modulators of smoking-induced gene expression changes in human airway epithelium. Proceedings of the National Academy of Sciences of the United States of America. 106: 2319-24. PMID 19168627 DOI: 10.1073/Pnas.0806383106  0.373
2009 Beane J, Spira A, Lenburg ME. Clinical impact of high-throughput gene expression studies in lung cancer. Journal of Thoracic Oncology : Official Publication of the International Association For the Study of Lung Cancer. 4: 109-18. PMID 19096318 DOI: 10.1097/Jto.0B013E31819151F8  0.473
2009 Wolf D, Das D, Lenburg M, Paquette J, Spellman P, Gray J, Pusztai L, Symmans F, Hatzis C, Esserman L, Veer Lv', Investigators I. From the Lab to the Clinic: Gene-Expression Profiles That Are Associated with Mek-Inhibitor SensitivityIn VitroAre Coordinately Co-Expressed in Breast Cancer Biopsy Samples from the I-SPY Trial (CALGB 150007/150012, ACRIN 6657). Cancer Research. 69: 2042-2042. DOI: 10.1158/0008-5472.Sabcs-09-2042  0.389
2009 Parker J, Prat A, Cheang M, Lenburg M, Paik S, Perou C. Breast Cancer Molecular Subtypes Predict Response to Anthracycline/Taxane-Based Chemotherapy. Cancer Research. 69: 2019-2019. DOI: 10.1158/0008-5472.Sabcs-09-2019  0.34
2009 Veer Lv', Das D, DeMichele A, Lenburg M, Singh B, Gray J, Berry D, Hylton N, Esserman L, Investigators I. Neoadjuvant Response in the Context of a Biologically Defined Low or High Risk Tumor Has a Different Clinical Consequence, the I-SPY Trial (CALGB 150007/150012, ACRIN 6657). Cancer Research. 69: 2003-2003. DOI: 10.1158/0008-5472.Sabcs-09-2003  0.324
2008 Beane J, Sebastiani P, Whitfield TH, Steiling K, Dumas YM, Lenburg ME, Spira A. A prediction model for lung cancer diagnosis that integrates genomic and clinical features. Cancer Prevention Research (Philadelphia, Pa.). 1: 56-64. PMID 19138936 DOI: 10.1158/1940-6207.Capr-08-0011  0.471
2008 Merritt WM, Lin YG, Han LY, Kamat AA, Spannuth WA, Schmandt R, Urbauer D, Pennacchio LA, Cheng JF, Nick AM, Deavers MT, Mourad-Zeidan A, Wang H, Mueller P, Lenburg ME, et al. Dicer, Drosha, and outcomes in patients with ovarian cancer. The New England Journal of Medicine. 359: 2641-50. PMID 19092150 DOI: 10.1056/Nejmoa0803785  0.314
2008 Zeskind JE, Lenburg ME, Spira A. Translating the COPD transcriptome: insights into pathogenesis and tools for clinical management. Proceedings of the American Thoracic Society. 5: 834-41. PMID 19017738 DOI: 10.1513/pats.200807-074TH  0.375
2008 Sridhar S, Schembri F, Zeskind J, Shah V, Gustafson AM, Steiling K, Liu G, Dumas YM, Zhang X, Brody JS, Lenburg ME, Spira A. Smoking-induced gene expression changes in the bronchial airway are reflected in nasal and buccal epithelium. Bmc Genomics. 9: 259. PMID 18513428 DOI: 10.1186/1471-2164-9-259  0.444
2008 Blick T, Widodo E, Hugo H, Waltham M, Lenburg ME, Neve RM, Thompson EW. Epithelial mesenchymal transition traits in human breast cancer cell lines. Clinical & Experimental Metastasis. 25: 629-42. PMID 18461285 DOI: 10.1007/S10585-008-9170-6  0.361
2008 Tripathi A, King C, de la Morenas A, Perry VK, Burke B, Antoine GA, Hirsch EF, Kavanah M, Mendez J, Stone M, Gerry NP, Lenburg ME, Rosenberg CL. Gene expression abnormalities in histologically normal breast epithelium of breast cancer patients. International Journal of Cancer. Journal International Du Cancer. 122: 1557-66. PMID 18058819 DOI: 10.1002/Ijc.23267  0.431
2008 Millien G, Beane J, Lenburg M, Tsao PN, Lu J, Spira A, Ramirez MI. Characterization of the mid-foregut transcriptome identifies genes regulated during lung bud induction. Gene Expression Patterns : Gep. 8: 124-39. PMID 18023262 DOI: 10.1016/J.Modgep.2007.09.003  0.461
2007 Zhang X, Liu G, Lenburg ME, Spira A. Comparison of smoking-induced gene expression on Affymetrix Exon and 3'-based expression arrays. Genome Informatics. International Conference On Genome Informatics. 18: 247-57. PMID 18546492 DOI: 10.11234/Gi1990.18.247  0.448
2007 Beane J, Sebastiani P, Liu G, Brody JS, Lenburg ME, Spira A. Reversible and permanent effects of tobacco smoke exposure on airway epithelial gene expression. Genome Biology. 8: R201. PMID 17894889 DOI: 10.1186/Gb-2007-8-9-R201  0.369
2007 Spira A, Beane JE, Shah V, Steiling K, Liu G, Schembri F, Gilman S, Dumas YM, Calner P, Sebastiani P, Sridhar S, Beamis J, Lamb C, Anderson T, Gerry N, ... ... Lenburg ME, et al. Airway epithelial gene expression in the diagnostic evaluation of smokers with suspect lung cancer. Nature Medicine. 13: 361-6. PMID 17334370 DOI: 10.1038/Nm1556  0.528
2007 Lenburg ME, Sinha A, Faller DV, Denis GV. Tumor-specific and proliferation-specific gene expression typifies murine transgenic B cell lymphomagenesis. The Journal of Biological Chemistry. 282: 4803-11. PMID 17166848 DOI: 10.1074/Jbc.M605870200  0.38
2007 Tchkonia T, Lenburg M, Thomou T, Giorgadze N, Frampton G, Pirtskhalava T, Cartwright A, Cartwright M, Flanagan J, Karagiannides I, Gerry N, Forse RA, Tchoukalova Y, Jensen MD, Pothoulakis C, et al. Identification of depot-specific human fat cell progenitors through distinct expression profiles and developmental gene patterns American Journal of Physiology - Endocrinology and Metabolism. 292: E298-E307. PMID 16985259 DOI: 10.1152/Ajpendo.00202.2006  0.328
2005 Klings ES, Safaya S, Adewoye AH, Odhiambo A, Frampton G, Lenburg M, Gerry N, Sebastiani P, Steinberg MH, Farber HW. Differential gene expression in pulmonary artery endothelial cells exposed to sickle cell plasma. Physiological Genomics. 21: 293-8. PMID 15741505 DOI: 10.1152/Physiolgenomics.00246.2004  0.374
2005 King C, Guo N, Frampton GM, Gerry NP, Lenburg ME, Rosenberg CL. Reliability and reproducibility of gene expression measurements using amplified RNA from laser-microdissected primary breast tissue with oligonucleotide arrays. The Journal of Molecular Diagnostics : Jmd. 7: 57-64. PMID 15681475 DOI: 10.1016/S1525-1578(10)60009-8  0.35
2003 Lenburg ME, Liou LS, Gerry NP, Frampton GM, Cohen HT, Christman MF. Previously unidentified changes in renal cell carcinoma gene expression identified by parametric analysis of microarray data. Bmc Cancer. 3: 31. PMID 14641932 DOI: 10.1186/1471-2407-3-31  0.351
2001 Lenburg ME, O'Shea EK. Genetic evidence for a morphogenetic function of the Saccharomyces cerevisiae Pho85 cyclin-dependent kinase. Genetics. 157: 39-51. PMID 11139490  0.546
1996 Lenburg ME, O'Shea EK. Signaling phosphate starvation. Trends in Biochemical Sciences. 21: 383-7. PMID 8918192 DOI: 10.1016/S0968-0004(96)10048-7  0.574
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