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Hilary H. Nickols, Ph.D. - Publications

Affiliations: 
2004 Vanderbilt University, Nashville, TN 
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7 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2015 Nickols HH, Yuh JP, Gregory KJ, Morrison RD, Bates BS, Stauffer SR, Emmitte KA, Bubser M, Peng W, Nedelcovych MT, Thompson A, Lv X, Xiang Z, Daniels JS, Niswender CM, et al. VU0477573: Partial negative allosteric modulator of the subtype 5 metabotropic glutamate receptor with in vivo efficacy. The Journal of Pharmacology and Experimental Therapeutics. PMID 26503377 DOI: 10.1124/Jpet.115.226597  0.383
2014 Dhanya RP, Sheffler DJ, Dahl R, Davis M, Lee PS, Yang L, Nickols HH, Cho HP, Smith LH, D'Souza MS, Conn PJ, Der-Avakian A, Markou A, Cosford ND. Design and synthesis of systemically active metabotropic glutamate subtype-2 and -3 (mGlu2/3) receptor positive allosteric modulators (PAMs): pharmacological characterization and assessment in a rat model of cocaine dependence. Journal of Medicinal Chemistry. 57: 4154-72. PMID 24735492 DOI: 10.1021/Jm5000563  0.402
2014 Nickols HH, Conn JP. Development of allosteric modulators of GPCRs for treatment of CNS disorders Neurobiology of Disease. 61: 55-71. PMID 24076101 DOI: 10.1016/J.Nbd.2013.09.013  0.386
2012 Sidique S, Dhanya RP, Sheffler DJ, Nickols HH, Yang L, Dahl R, Mangravita-Novo A, Smith LH, D'Souza MS, Semenova S, Conn PJ, Markou A, Cosford ND. Orally active metabotropic glutamate subtype 2 receptor positive allosteric modulators: structure-activity relationships and assessment in a rat model of nicotine dependence. Journal of Medicinal Chemistry. 55: 9434-45. PMID 23009245 DOI: 10.1021/Jm3005306  0.366
2004 Nickols HH, Shah VN, Chazin WJ, Limbird LE. Calmodulin interacts with the V2 vasopressin receptor: elimination of binding to the C terminus also eliminates arginine vasopressin-stimulated elevation of intracellular calcium. The Journal of Biological Chemistry. 279: 46969-80. PMID 15319442 DOI: 10.1074/Jbc.M407351200  0.552
2004 Tan CM, Brady AE, Nickols HH, Wang Q, Limbird LE. Membrane trafficking of G protein-coupled receptors. Annual Review of Pharmacology and Toxicology. 44: 559-609. PMID 14744258 DOI: 10.1146/Annurev.Pharmtox.44.101802.121558  0.524
2003 Tan CM, Nickols HH, Limbird LE. Appropriate polarization following pharmacological rescue of V2 vasopressin receptors encoded by X-linked nephrogenic diabetes insipidus alleles involves a conformation of the receptor that also attains mature glycosylation. The Journal of Biological Chemistry. 278: 35678-86. PMID 12824183 DOI: 10.1074/Jbc.M301888200  0.562
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