Ian W. Glaaser, Ph.D. - Publications

Affiliations: 
2010 Columbia University, New York, NY 

26/27 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Mathiharan YK, Glaaser IW, Zhao Y, Robertson MJ, Skiniotis G, Slesinger PA. Structural insights into GIRK2 channel modulation by cholesterol and PIP. Cell Reports. 36: 109619. PMID 34433062 DOI: 10.1016/j.celrep.2021.109619  0.41
2021 Zhao Y, Gameiro-Ros I, Glaaser IW, Slesinger PA. Advances in Targeting GIRK Channels in Disease. Trends in Pharmacological Sciences. 42: 203-215. PMID 33468322 DOI: 10.1016/j.tips.2020.12.002  0.367
2020 Zhao Y, Ung PM, Zahoránszky-Kőhalmi G, Zakharov AV, Martinez NJ, Simeonov A, Glaaser IW, Rai G, Schlessinger A, Marugan JJ, Slesinger PA. Identification of a G-Protein-Independent Activator of GIRK Channels. Cell Reports. 31: 107770. PMID 32553165 DOI: 10.1016/J.Celrep.2020.107770  0.46
2020 Glaaser IW, Mathiharan YK, Zhao Y, Skiniotis G, Slesinger PA. CRYO-EM Structures of the GIRK2 Channel Reveal Mechanisms for Lipid Modulation Biophysical Journal. 118: 497a-498a. DOI: 10.1016/J.Bpj.2019.11.2749  0.523
2017 Lacin E, Aryal P, Glaaser IW, Bodhinathan K, Tsai E, Marsh N, Tucker SJ, Sansom MSP, Slesinger PA. Dynamic role of the tether helix in PIP2-dependent gating of a G protein-gated potassium channel. The Journal of General Physiology. PMID 28720589 DOI: 10.1085/Jgp.201711801  0.515
2017 Glaaser IW, Slesinger PA. Dual activation of neuronal G protein-gated inwardly rectifying potassium (GIRK) channels by cholesterol and alcohol. Scientific Reports. 7: 4592. PMID 28676630 DOI: 10.1038/S41598-017-04681-X  0.4
2017 Glaaser IW, Slesinger PA. Small Molecule Modulation of Brain GIRK Channels Biophysical Journal. 112: 182a-183a. DOI: 10.1016/J.Bpj.2016.11.1012  0.45
2015 Glaaser IW, Slesinger PA. Structural Insights into GIRK Channel Function. International Review of Neurobiology. 123: 117-60. PMID 26422984 DOI: 10.1016/Bs.Irn.2015.05.014  0.524
2015 Glaaser IW, Marsh NO, Choe S, Slesinger PA. Alcohol Inhibition of a Chemically-Activated GIRK2 Channel Biophysical Journal. 108: 367a. DOI: 10.1016/J.Bpj.2014.11.2013  0.352
2012 Glaaser IW, Osteen JD, Puckerin A, Sampson KJ, Jin X, Kass RS. Perturbation of sodium channel structure by an inherited Long QT Syndrome mutation. Nature Communications. 3: 706. PMID 22426227 DOI: 10.1038/Ncomms1717  0.746
2011 Glaaser IW, Osteen JD, Puckerin A, Kass RS. Mapping the Structure of the Cardiac Voltage-Gated Sodium Channel (Nav1.5) C-Terminus: Implications of An Lqt3 Mutant Biophysical Journal. 100: 15a. DOI: 10.1016/J.Bpj.2010.12.293  0.717
2008 Holland KD, Kearney JA, Glauser TA, Buck G, Keddache M, Blankston JR, Glaaser IW, Kass RS, Meisler MH. Mutation of sodium channel SCN3A in a patient with cryptogenic pediatric partial epilepsy. Neuroscience Letters. 433: 65-70. PMID 18242854 DOI: 10.1016/J.Neulet.2007.12.064  0.668
2007 Bankston JR, Sampson KJ, Kateriya S, Glaaser IW, Malito DL, Chung WK, Kass RS. A novel LQT-3 mutation disrupts an inactivation gate complex with distinct rate-dependent phenotypic consequences. Channels (Austin, Tex.). 1: 273-80. PMID 18708744 DOI: 10.4161/Chan.4956  0.748
2007 Kass RS, Cormier JW, Glaaser IW. The Cardiac Sodium-Channel Carboxy Terminus: Predicted and Detected Structure Provide a Novel Target For Antiarrhythmic Drugs Development New Arrhythmia Technologies. 36-47. DOI: 10.1002/9780470988725.ch4  0.717
2006 Glaaser IW, Bankston JR, Liu H, Tateyama M, Kass RS. A carboxyl-terminal hydrophobic interface is critical to sodium channel function. Relevance to inherited disorders. The Journal of Biological Chemistry. 281: 24015-23. PMID 16798729 DOI: 10.1074/Jbc.M605473200  0.764
2006 Glaaser IW, Clancy CE. Cardiac Na+ channels as therapeutic targets for antiarrhythmic agents. Handbook of Experimental Pharmacology. 99-121. PMID 16610342 DOI: 10.1007/3-540-29715-4_4  0.604
2005 Lam AD, Chikina MD, McNulty MM, Glaaser IW, Hanck DA. Role of Domain IV/S4 outermost arginines in gating of T-type calcium channels. Pflã¼Gers Archiv : European Journal of Physiology. 451: 349-61. PMID 16133267 DOI: 10.1007/S00424-005-1407-5  0.474
2004 Sunami A, Tracey A, Glaaser IW, Lipkind GM, Hanck DA, Fozzard HA. Accessibility of mid-segment domain IV S6 residues of the voltage-gated Na+ channel to methanethiosulfonate reagents. The Journal of Physiology. 561: 403-13. PMID 15579536 DOI: 10.1113/jphysiol.2004.067579  0.518
2004 Sandtner W, Szendroedi J, Zarrabi T, Zebedin E, Hilber K, Glaaser I, Fozzard HA, Dudley SC, Todt H. Lidocaine: A foot in the door of the inner vestibule prevents ultra-slow inactivation of a voltage-gated sodium channel Molecular Pharmacology. 66: 648-657. PMID 15322257 DOI: 10.1124/Mol.66.3  0.541
2004 Motoike HK, Liu H, Glaaser IW, Yang AS, Tateyama M, Kass RS. The Na+ channel inactivation gate is a molecular complex: a novel role of the COOH-terminal domain. The Journal of General Physiology. 123: 155-65. PMID 14744988 DOI: 10.1085/Jgp.200308929  0.731
2003 Glaaser IW, Kass RS, Clancy CE. Mechanisms of genetic arrhythmias: from DNA to ECG. Progress in Cardiovascular Diseases. 46: 259-70. PMID 14685943 DOI: 10.1016/S0033-0620(03)00073-2  0.591
2003 Bai CX, Glaaser IW, Sawanobori T, Sunami A. Involvement of local anesthetic binding sites on IVS6 of sodium channels in fast and slow inactivation. Neuroscience Letters. 337: 41-5. PMID 12524167 DOI: 10.1016/S0304-3940(02)01288-0  0.424
2002 Hilber K, Sandtner W, Kudlacek O, Schreiner B, Glaaser I, Schütz W, Fozzard HA, Dudley SC, Todt H. Interaction between fast and ultra-slow inactivation in the voltage-gated sodium channel. Does the inactivation gate stabilize the channel structure? Journal of Biological Chemistry. 277: 37105-37115. PMID 12138168 DOI: 10.1074/jbc.M205661200  0.534
2001 Hilber K, Sandtner W, Kudlacek O, Glaaser IW, Weisz E, Kyle JW, French RJ, Fozzard HA, Dudley SC, Todt H. The selectivity filter of the voltage-gated sodium channel is involved in channel activation. The Journal of Biological Chemistry. 276: 27831-9. PMID 11382756 DOI: 10.1074/jbc.M101933200  0.504
2001 Sunami A, Glaaser IW, Fozzard HA. Structural and gating changes of the sodium channel induced by mutation of a residue in the upper third of IVS6, creating an external access path for local anesthetics. Molecular Pharmacology. 59: 684-91. PMID 11259611  0.401
2000 Sunami A, Glaaser IW, Fozzard HA. A critical residue for isoform difference in tetrodotoxin affinity is a molecular determinant of the external access path for local anesthetics in the cardiac sodium channel. Proceedings of the National Academy of Sciences of the United States of America. 97: 2326-31. PMID 10681444 DOI: 10.1073/pnas.030438797  0.521
Low-probability matches (unlikely to be authored by this person)
2019 Zuo H, Glaaser I, Zhao Y, Kurinov I, Mosyak L, Wang H, Liu J, Park J, Frangaj A, Sturchler E, Zhou M, McDonald P, Geng Y, Slesinger PA, Fan QR. Structural basis for auxiliary subunit KCTD16 regulation of the GABA receptor. Proceedings of the National Academy of Sciences of the United States of America. PMID 30971491 DOI: 10.1073/Pnas.1903024116  0.292
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