Anita B. Hjelmeland, Ph.D. - Publications

Affiliations: 
2003 Duke University, Durham, NC 
Area:
Somatosensory

48 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2015 Tilson SG, Haley EM, Triantafillu UL, Dozier DA, Langford CP, Gillespie GY, Kim Y. ROCK Inhibition Facilitates In Vitro Expansion of Glioblastoma Stem-Like Cells. Plos One. 10: e0132823. PMID 26167936 DOI: 10.1371/journal.pone.0132823  0.56
2015 Cheng P, Phillips E, Kim SH, Taylor D, Hielscher T, Puccio L, Hjelmeland AB, Lichter P, Nakano I, Goidts V. Kinome-wide shRNA screen identifies the receptor tyrosine kinase AXL as a key regulator for mesenchymal glioblastoma stem-like cells. Stem Cell Reports. 4: 899-913. PMID 25921812 DOI: 10.1016/j.stemcr.2015.03.005  0.56
2015 Stoltz K, Sinyuk M, Hale JS, Wu Q, Otvos B, Walker K, Vasanji A, Rich JN, Hjelmeland AB, Lathia JD. Development of a Sox2 reporter system modeling cellular heterogeneity in glioma. Neuro-Oncology. 17: 361-71. PMID 25416826 DOI: 10.1093/neuonc/nou320  0.56
2014 Moskwa P, Zinn PO, Choi YE, Shukla SA, Fendler W, Chen CC, Lu J, Golub TR, Hjelmeland A, Chowdhury D. A functional screen identifies miRs that induce radioresistance in glioblastomas. Molecular Cancer Research : McR. 12: 1767-78. PMID 25256711 DOI: 10.1158/1541-7786.MCR-14-0268  0.56
2014 Liu JK, Lubelski D, Schonberg DL, Wu Q, Hale JS, Flavahan WA, Mulkearns-Hubert EE, Man J, Hjelmeland AB, Yu J, Lathia JD, Rich JN. Phage display discovery of novel molecular targets in glioblastoma-initiating cells. Cell Death and Differentiation. 21: 1325-39. PMID 24832468 DOI: 10.1038/cdd.2014.65  0.56
2014 Yan K, Wu Q, Yan DH, Lee CH, Rahim N, Tritschler I, DeVecchio J, Kalady MF, Hjelmeland AB, Rich JN. Glioma cancer stem cells secrete Gremlin1 to promote their maintenance within the tumor hierarchy. Genes & Development. 28: 1085-100. PMID 24788093 DOI: 10.1101/gad.235515.113  0.56
2014 Scott JG, Hjelmeland AB, Chinnaiyan P, Anderson AR, Basanta D. Microenvironmental variables must influence intrinsic phenotypic parameters of cancer stem cells to affect tumourigenicity. Plos Computational Biology. 10: e1003433. PMID 24453958 DOI: 10.1371/journal.pcbi.1003433  0.56
2014 Lathia JD, Li M, Sinyuk M, Alvarado AG, Flavahan WA, Stoltz K, Rosager AM, Hale J, Hitomi M, Gallagher J, Wu Q, Martin J, Vidal JG, Nakano I, Dahlrot RH, ... ... Hjelmeland AB, et al. High-throughput flow cytometry screening reveals a role for junctional adhesion molecule a as a cancer stem cell maintenance factor. Cell Reports. 6: 117-29. PMID 24373972 DOI: 10.1016/j.celrep.2013.11.043  0.56
2014 Venere M, Hamerlik P, Wu Q, Rasmussen RD, Song LA, Vasanji A, Tenley N, Flavahan WA, Hjelmeland AB, Bartek J, Rich JN. Therapeutic targeting of constitutive PARP activation compromises stem cell phenotype and survival of glioblastoma-initiating cells. Cell Death and Differentiation. 21: 258-69. PMID 24121277 DOI: 10.1038/cdd.2013.136  0.56
2013 Lotti F, Jarrar AM, Pai RK, Hitomi M, Lathia J, Mace A, Gantt GA, Sukhdeo K, DeVecchio J, Vasanji A, Leahy P, Hjelmeland AB, Kalady MF, Rich JN. Chemotherapy activates cancer-associated fibroblasts to maintain colorectal cancer-initiating cells by IL-17A. The Journal of Experimental Medicine. 210: 2851-72. PMID 24323355 DOI: 10.1084/jem.20131195  0.56
2013 Flavahan WA, Wu Q, Hitomi M, Rahim N, Kim Y, Sloan AE, Weil RJ, Nakano I, Sarkaria JN, Stringer BW, Day BW, Li M, Lathia JD, Rich JN, Hjelmeland AB. Brain tumor initiating cells adapt to restricted nutrition through preferential glucose uptake. Nature Neuroscience. 16: 1373-82. PMID 23995067 DOI: 10.1038/nn.3510  0.56
2013 Kim Y, Wu Q, Hamerlik P, Hitomi M, Sloan AE, Barnett GH, Weil RJ, Leahy P, Hjelmeland AB, Rich JN. Aptamer identification of brain tumor-initiating cells. Cancer Research. 73: 4923-36. PMID 23796560 DOI: 10.1158/0008-5472.CAN-12-4556  0.56
2013 Sukhdeo K, Paramban RI, Vidal JG, Elia J, Martin J, Rivera M, Carrasco DR, Jarrar A, Kalady MF, Carson CT, Balderas R, Hjelmeland AB, Lathia JD, Rich JN. Multiplex flow cytometry barcoding and antibody arrays identify surface antigen profiles of primary and metastatic colon cancer cell lines. Plos One. 8: e53015. PMID 23308131 DOI: 10.1371/journal.pone.0053015  0.56
2012 Lathia JD, Li M, Hall PE, Gallagher J, Hale JS, Wu Q, Venere M, Levy E, Rani MR, Huang P, Bae E, Selfridge J, Cheng L, Guvenc H, McLendon RE, ... ... Hjelmeland AB, et al. Laminin alpha 2 enables glioblastoma stem cell growth. Annals of Neurology. 72: 766-78. PMID 23280793 DOI: 10.1002/ana.23674  0.56
2012 Hjelmeland AB, Rich JN. The quest for self-identity: not all cancer stem cells are the same. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 18: 3495-8. PMID 22711710 DOI: 10.1158/1078-0432.CCR-12-1456  0.56
2012 Heddleston JM, Wu Q, Rivera M, Minhas S, Lathia JD, Sloan AE, Iliopoulos O, Hjelmeland AB, Rich JN. Hypoxia-induced mixed-lineage leukemia 1 regulates glioma stem cell tumorigenic potential. Cell Death and Differentiation. 19: 428-39. PMID 21836617 DOI: 10.1038/cdd.2011.109  0.56
2011 Hjelmeland AB, Lathia JD, Sathornsumetee S, Rich JN. Twisted tango: brain tumor neurovascular interactions. Nature Neuroscience. 14: 1375-81. PMID 22030548 DOI: 10.1038/nn.2955  0.56
2011 Lathia JD, Gallagher J, Myers JT, Li M, Vasanji A, McLendon RE, Hjelmeland AB, Huang AY, Rich JN. Direct in vivo evidence for tumor propagation by glioblastoma cancer stem cells. Plos One. 6: e24807. PMID 21961046 DOI: 10.1371/journal.pone.0024807  0.56
2011 Lathia JD, Hitomi M, Gallagher J, Gadani SP, Adkins J, Vasanji A, Liu L, Eyler CE, Heddleston JM, Wu Q, Minhas S, Soeda A, Hoeppner DJ, Ravin R, McKay RD, ... ... Hjelmeland AB, et al. Distribution of CD133 reveals glioma stem cells self-renew through symmetric and asymmetric cell divisions. Cell Death & Disease. 2: e200. PMID 21881602 DOI: 10.1038/cddis.2011.80  0.56
2011 Heddleston JM, Hitomi M, Venere M, Flavahan WA, Yang K, Kim Y, Minhas S, Rich JN, Hjelmeland AB. Glioma stem cell maintenance: the role of the microenvironment. Current Pharmaceutical Design. 17: 2386-401. PMID 21827414 DOI: 10.2174/138161211797249260  0.56
2011 Eyler CE, Wu Q, Yan K, MacSwords JM, Chandler-Militello D, Misuraca KL, Lathia JD, Forrester MT, Lee J, Stamler JS, Goldman SA, Bredel M, McLendon RE, Sloan AE, Hjelmeland AB, et al. Glioma stem cell proliferation and tumor growth are promoted by nitric oxide synthase-2. Cell. 146: 53-66. PMID 21729780 DOI: 10.1016/j.cell.2011.06.006  0.56
2011 Guryanova OA, Wu Q, Cheng L, Lathia JD, Huang Z, Yang J, MacSwords J, Eyler CE, McLendon RE, Heddleston JM, Shou W, Hambardzumyan D, Lee J, Hjelmeland AB, Sloan AE, et al. Nonreceptor tyrosine kinase BMX maintains self-renewal and tumorigenic potential of glioblastoma stem cells by activating STAT3. Cancer Cell. 19: 498-511. PMID 21481791 DOI: 10.1016/j.ccr.2011.03.004  0.56
2011 Hjelmeland AB, Rich JN. Molecular targeting of neural cancer stem cells: TTAGGG, you're it! Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 17: 3-5. PMID 21208901 DOI: 10.1158/1078-0432.CCR-10-2686  0.56
2011 Hjelmeland AB, Wu Q, Heddleston JM, Choudhary GS, MacSwords J, Lathia JD, McLendon R, Lindner D, Sloan A, Rich JN. Acidic stress promotes a glioma stem cell phenotype. Cell Death and Differentiation. 18: 829-40. PMID 21127501 DOI: 10.1038/cdd.2010.150  0.56
2010 Cao Y, Lathia JD, Eyler CE, Wu Q, Li Z, Wang H, McLendon RE, Hjelmeland AB, Rich JN. Erythropoietin Receptor Signaling Through STAT3 Is Required For Glioma Stem Cell Maintenance. Genes & Cancer. 1: 50-61. PMID 20657792 DOI: 10.1177/1947601909356352  0.56
2010 Lathia JD, Gallagher J, Heddleston JM, Wang J, Eyler CE, Macswords J, Wu Q, Vasanji A, McLendon RE, Hjelmeland AB, Rich JN. Integrin alpha 6 regulates glioblastoma stem cells. Cell Stem Cell. 6: 421-32. PMID 20452317 DOI: 10.1016/j.stem.2010.02.018  0.56
2010 Hjelmeland AB, Wu Q, Wickman S, Eyler C, Heddleston J, Shi Q, Lathia JD, Macswords J, Lee J, McLendon RE, Rich JN. Targeting A20 decreases glioma stem cell survival and tumor growth. Plos Biology. 8: e1000319. PMID 20186265 DOI: 10.1371/journal.pbio.1000319  0.56
2010 Heddleston JM, Li Z, Lathia JD, Bao S, Hjelmeland AB, Rich JN. Hypoxia inducible factors in cancer stem cells. British Journal of Cancer. 102: 789-95. PMID 20104230 DOI: 10.1038/sj.bjc.6605551  0.56
2010 Wang J, Wakeman TP, Lathia JD, Hjelmeland AB, Wang XF, White RR, Rich JN, Sullenger BA. Notch promotes radioresistance of glioma stem cells. Stem Cells (Dayton, Ohio). 28: 17-28. PMID 19921751 DOI: 10.1002/stem.261  0.56
2009 Heddleston JM, Li Z, McLendon RE, Hjelmeland AB, Rich JN. The hypoxic microenvironment maintains glioblastoma stem cells and promotes reprogramming towards a cancer stem cell phenotype. Cell Cycle (Georgetown, Tex.). 8: 3274-84. PMID 19770585  0.56
2009 Wang H, Lathia JD, Wu Q, Wang J, Li Z, Heddleston JM, Eyler CE, Elderbroom J, Gallagher J, Schuschu J, MacSwords J, Cao Y, McLendon RE, Wang XF, Hjelmeland AB, et al. Targeting interleukin 6 signaling suppresses glioma stem cell survival and tumor growth. Stem Cells (Dayton, Ohio). 27: 2393-404. PMID 19658188 DOI: 10.1002/stem.188  0.56
2009 Schilling SH, Hjelmeland AB, Radiloff DR, Liu IM, Wakeman TP, Fielhauer JR, Foster EH, Lathia JD, Rich JN, Wang XF, Datto MB. NDRG4 is required for cell cycle progression and survival in glioblastoma cells. The Journal of Biological Chemistry. 284: 25160-9. PMID 19592488 DOI: 10.1074/jbc.M109.012484  0.56
2009 Li Z, Bao S, Wu Q, Wang H, Eyler C, Sathornsumetee S, Shi Q, Cao Y, Lathia J, McLendon RE, Hjelmeland AB, Rich JN. Hypoxia-inducible factors regulate tumorigenic capacity of glioma stem cells. Cancer Cell. 15: 501-13. PMID 19477429 DOI: 10.1016/j.ccr.2009.03.018  0.56
2009 Li Z, Wang H, Eyler CE, Hjelmeland AB, Rich JN. Turning cancer stem cells inside out: an exploration of glioma stem cell signaling pathways. The Journal of Biological Chemistry. 284: 16705-9. PMID 19286664 DOI: 10.1074/jbc.R900013200  0.56
2008 Wang J, Wang H, Li Z, Wu Q, Lathia JD, McLendon RE, Hjelmeland AB, Rich JN. c-Myc is required for maintenance of glioma cancer stem cells. Plos One. 3: e3769. PMID 19020659 DOI: 10.1371/journal.pone.0003769  0.56
2008 Eyler CE, Foo WC, LaFiura KM, McLendon RE, Hjelmeland AB, Rich JN. Brain cancer stem cells display preferential sensitivity to Akt inhibition. Stem Cells (Dayton, Ohio). 26: 3027-36. PMID 18802038 DOI: 10.1634/stemcells.2007-1073  0.56
2008 Bao S, Wu Q, Li Z, Sathornsumetee S, Wang H, McLendon RE, Hjelmeland AB, Rich JN. Targeting cancer stem cells through L1CAM suppresses glioma growth. Cancer Research. 68: 6043-8. PMID 18676824 DOI: 10.1158/0008-5472.CAN-08-1079  0.56
2007 Hjelmeland AB, Lattimore KP, Fee BE, Shi Q, Wickman S, Keir ST, Hjelmeland MD, Batt D, Bigner DD, Friedman HS, Rich JN. The combination of novel low molecular weight inhibitors of RAF (LBT613) and target of rapamycin (RAD001) decreases glioma proliferation and invasion. Molecular Cancer Therapeutics. 6: 2449-57. PMID 17766837 DOI: 10.1158/1535-7163.MCT-07-0155  0.56
2007 Shi Q, Hjelmeland AB, Keir ST, Song L, Wickman S, Jackson D, Ohmori O, Bigner DD, Friedman HS, Rich JN. A novel low-molecular weight inhibitor of focal adhesion kinase, TAE226, inhibits glioma growth. Molecular Carcinogenesis. 46: 488-96. PMID 17219439 DOI: 10.1002/mc.20297  0.56
2007 Shi Q, Bao S, Song L, Wu Q, Bigner DD, Hjelmeland AB, Rich JN. Targeting SPARC expression decreases glioma cellular survival and invasion associated with reduced activities of FAK and ILK kinases. Oncogene. 26: 4084-94. PMID 17213807 DOI: 10.1038/sj.onc.1210181  0.56
2006 Bao S, Wu Q, McLendon RE, Hao Y, Shi Q, Hjelmeland AB, Dewhirst MW, Bigner DD, Rich JN. Glioma stem cells promote radioresistance by preferential activation of the DNA damage response. Nature. 444: 756-60. PMID 17051156 DOI: 10.1038/nature05236  0.56
2006 DeKroon R, Robinette JB, Hjelmeland AB, Wiggins E, Blackwell M, Mihovilovic M, Fujii M, York J, Hart J, Kontos C, Rich J, Strittmatter WJ. APOE4-VLDL inhibits the HDL-activated phosphatidylinositol 3-kinase/Akt Pathway via the phosphoinositol phosphatase SHIP2. Circulation Research. 99: 829-36. PMID 16973905 DOI: 10.1161/01.RES.0000245479.03190.9f  0.56
2006 Sathornsumetee S, Hjelmeland AB, Keir ST, McLendon RE, Batt D, Ramsey T, Yusuff N, Rasheed BK, Kieran MW, Laforme A, Bigner DD, Friedman HS, Rich JN. AAL881, a novel small molecule inhibitor of RAF and vascular endothelial growth factor receptor activities, blocks the growth of malignant glioma. Cancer Research. 66: 8722-30. PMID 16951188 DOI: 10.1158/0008-5472.CAN-06-0284  0.56
2006 Bao S, Wu Q, Sathornsumetee S, Hao Y, Li Z, Hjelmeland AB, Shi Q, McLendon RE, Bigner DD, Rich JN. Stem cell-like glioma cells promote tumor angiogenesis through vascular endothelial growth factor. Cancer Research. 66: 7843-8. PMID 16912155 DOI: 10.1158/0008-5472.CAN-06-1010  0.56
2005 Hjelmeland AB, Hjelmeland MD, Shi Q, Hart JL, Bigner DD, Wang XF, Kontos CD, Rich JN. Loss of phosphatase and tensin homologue increases transforming growth factor beta-mediated invasion with enhanced SMAD3 transcriptional activity. Cancer Research. 65: 11276-81. PMID 16357132 DOI: 10.1158/0008-5472.CAN-05-3016  0.56
2005 Hjelmeland AB, Schilling SH, Guo X, Quarles D, Wang XF. Loss of Smad3-mediated negative regulation of Runx2 activity leads to an alteration in cell fate determination. Molecular and Cellular Biology. 25: 9460-8. PMID 16227596 DOI: 10.1128/MCB.25.21.9460-9468.2005  0.56
2004 Hjelmeland MD, Hjelmeland AB, Sathornsumetee S, Reese ED, Herbstreith MH, Laping NJ, Friedman HS, Bigner DD, Wang XF, Rich JN. SB-431542, a small molecule transforming growth factor-beta-receptor antagonist, inhibits human glioma cell line proliferation and motility. Molecular Cancer Therapeutics. 3: 737-45. PMID 15210860  0.56
2004 Xiao ZS, Hjelmeland AB, Quarles LD. Selective deficiency of the "bone-related" Runx2-II unexpectedly preserves osteoblast-mediated skeletogenesis. The Journal of Biological Chemistry. 279: 20307-13. PMID 15007057 DOI: 10.1074/jbc.M401109200  0.56
Show low-probability matches.