Stephen Schilling, Ph.D. - Publications

Affiliations: 
2009 Pharmacology Duke University, Durham, NC 
Area:
Somatosensory

80 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2015 Frost JL, Liu B, Rahfeld JU, Kleinschmidt M, O'Nuallain B, Le KX, Lues I, Caldarone BJ, Schilling S, Demuth HU, Lemere CA. An anti-pyroglutamate-3 Aβ vaccine reduces plaques and improves cognition in APPswe/PS1ΔE9 mice. Neurobiology of Aging. PMID 26453001 DOI: 10.1016/j.neurobiolaging.2015.08.021  0.52
2015 Becker A, Eichentopf R, Sedlmeier R, Waniek A, Cynis H, Koch B, Stephan A, Bäuscher C, Kohlmann S, Hoffmann T, Kehlen A, Berg S, Freyse EJ, Osmand A, Plank AC, ... ... Schilling S, et al. IsoQC (QPCTL) knockout mice suggest differential substrate conversion by glutaminyl cyclase isoenzymes. Biological Chemistry. PMID 26351917 DOI: 10.1515/hsz-2015-0192  0.52
2015 Schlenzig D, Wermann M, Ramsbeck D, Moenke-Wedler T, Schilling S. Expression, purification and initial characterization of human meprin β from Pichia pastoris. Protein Expression and Purification. PMID 26256061 DOI: 10.1016/j.pep.2015.08.001  0.52
2015 Seifert F, Demuth HU, Weichler T, Ludwig HH, Tittmann K, Schilling S. Phosphate ions and glutaminyl cyclases catalyze the cyclization of glutaminyl residues by facilitating synchronized proton transfers. Bioorganic Chemistry. 60: 98-101. PMID 25981125 DOI: 10.1016/j.bioorg.2015.04.005  0.52
2015 Hartlage-Rübsamen M, Waniek A, Meissner J, Morawski M, Schilling S, Jäger C, Kleinschmidt M, Cynis H, Kehlen A, Arendt T, Demuth HU, Rossner S. Isoglutaminyl cyclase contributes to CCL2-driven neuroinflammation in Alzheimer's disease. Acta Neuropathologica. 129: 565-83. PMID 25666182 DOI: 10.1007/s00401-015-1395-2  0.52
2015 Waniek A, Hartlage-Rübsamen M, Höfling C, Kehlen A, Schilling S, Demuth HU, Roßner S. Identification of thyrotropin-releasing hormone as hippocampal glutaminyl cyclase substrate in neurons and reactive astrocytes. Biochimica Et Biophysica Acta. 1852: 146-55. PMID 25446989 DOI: 10.1016/j.bbadis.2014.11.011  0.52
2014 Höfling C, Indrischek H, Höpcke T, Waniek A, Cynis H, Koch B, Schilling S, Morawski M, Demuth HU, Roßner S, Hartlage-Rübsamen M. Mouse strain and brain region-specific expression of the glutaminyl cyclases QC and isoQC. International Journal of Developmental Neuroscience : the Official Journal of the International Society For Developmental Neuroscience. 36: 64-73. PMID 24886834 DOI: 10.1016/j.ijdevneu.2014.05.008  0.52
2014 Lison H, Happel MF, Schneider F, Baldauf K, Kerbstat S, Seelbinder B, Schneeberg J, Zappe M, Goldschmidt J, Budinger E, Schröder UH, Ohl FW, Schilling S, Demuth HU, Scheich H, et al. Disrupted cross-laminar cortical processing in β amyloid pathology precedes cell death. Neurobiology of Disease. 63: 62-73. PMID 24291517 DOI: 10.1016/j.nbd.2013.11.014  0.52
2014 Morawski M, Schilling S, Kreuzberger M, Waniek A, Jäger C, Koch B, Cynis H, Kehlen A, Arendt T, Hartlage-Rübsamen M, Demuth HU, Roßner S. Glutaminyl cyclase in human cortex: correlation with (pGlu)-amyloid-β load and cognitive decline in Alzheimer's disease. Journal of Alzheimer's Disease : Jad. 39: 385-400. PMID 24164736 DOI: 10.3233/JAD-131535  0.52
2014 Schilling SH, Spruill WM. PTO subject matter eligibility guidance: An Ill-advised overextension of myriad Biotechnology Law Report. 33: 120-132. DOI: 10.1089/blr.2014.9982  0.52
2013 Becker A, Kohlmann S, Alexandru A, Jagla W, Canneva F, Bäuscher C, Cynis H, Sedlmeier R, Graubner S, Schilling S, Demuth HU, von Hörsten S. Glutaminyl cyclase-mediated toxicity of pyroglutamate-beta amyloid induces striatal neurodegeneration. Bmc Neuroscience. 14: 108. PMID 24083638 DOI: 10.1186/1471-2202-14-108  0.52
2013 Frost JL, Le KX, Cynis H, Ekpo E, Kleinschmidt M, Palmour RM, Ervin FR, Snigdha S, Cotman CW, Saido TC, Vassar RJ, St George-Hyslop P, Ikezu T, Schilling S, Demuth HU, et al. Pyroglutamate-3 amyloid-β deposition in the brains of humans, non-human primates, canines, and Alzheimer disease-like transgenic mouse models. The American Journal of Pathology. 183: 369-81. PMID 23747948 DOI: 10.1016/j.ajpath.2013.05.005  0.52
2013 Cynis H, Kehlen A, Haegele M, Hoffmann T, Heiser U, Fujii M, Shibazaki Y, Yoneyama H, Schilling S, Demuth HU. Inhibition of Glutaminyl Cyclases alleviates CCL2-mediated inflammation of non-alcoholic fatty liver disease in mice. International Journal of Experimental Pathology. 94: 217-25. PMID 23560443 DOI: 10.1111/iep.12020  0.52
2013 Kolenko P, Koch B, Rahfeld JU, Schilling S, Demuth HU, Stubbs MT. Structure of glutaminyl cyclase from Drosophila melanogaster in space group I4. Acta Crystallographica. Section F, Structural Biology and Crystallization Communications. 69: 358-61. PMID 23545638 DOI: 10.1107/S1744309113005575  0.52
2013 Güttler BH, Cynis H, Seifert F, Ludwig HH, Porzel A, Schilling S. A quantitative analysis of spontaneous isoaspartate formation from N-terminal asparaginyl and aspartyl residues. Amino Acids. 44: 1205-14. PMID 23344882 DOI: 10.1007/s00726-012-1454-0  0.52
2013 Hellvard A, Maresz K, Schilling S, Graubner S, Heiser U, Jonsson R, Cynis H, Demuth HU, Potempa J, Mydel P. Glutaminyl cyclases as novel targets for the treatment of septic arthritis. The Journal of Infectious Diseases. 207: 768-77. PMID 23204180 DOI: 10.1093/infdis/jis729  0.52
2012 Fogh K, Andersen MB, Bischoff-Mikkelsen M, Bause R, Zutt M, Schilling S, Schmutz JL, Borbujo J, Jimenez JA, Cartier H, Jørgensen B. Clinically relevant pain relief with an ibuprofen-releasing foam dressing: results from a randomized, controlled, double-blind clinical trial in exuding, painful venous leg ulcers. Wound Repair and Regeneration : Official Publication of the Wound Healing Society [and] the European Tissue Repair Society. 20: 815-21. PMID 23110444 DOI: 10.1111/j.1524-475X.2012.00844.x  0.52
2012 Koch B, Buchholz M, Wermann M, Heiser U, Schilling S, Demuth HU. Probing secondary glutaminyl cyclase (QC) inhibitor interactions applying an in silico-modeling/site-directed mutagenesis approach: implications for drug development. Chemical Biology & Drug Design. 80: 937-46. PMID 22967026 DOI: 10.1111/cbdd.12046  0.52
2012 Koch B, Kolenko P, Buchholz M, Carrillo DR, Parthier C, Wermann M, Rahfeld JU, Reuter G, Schilling S, Stubbs MT, Demuth HU. Crystal structures of glutaminyl cyclases (QCs) from Drosophila melanogaster reveal active site conservation between insect and mammalian QCs. Biochemistry. 51: 7383-92. PMID 22897232 DOI: 10.1021/bi300687g  0.52
2012 Nussbaum JM, Schilling S, Cynis H, Silva A, Swanson E, Wangsanut T, Tayler K, Wiltgen B, Hatami A, Rönicke R, Reymann K, Hutter-Paier B, Alexandru A, Jagla W, Graubner S, et al. Prion-like behaviour and tau-dependent cytotoxicity of pyroglutamylated amyloid-β. Nature. 485: 651-5. PMID 22660329 DOI: 10.1038/nature11060  0.52
2012 Maltezou HC, Fusco FM, Schilling S, De Iaco G, Gottschalk R, Brodt HR, Bannister B, Brouqui P, Thomson G, Puro V, Ippolito G. Infection control practices in facilities for highly infectious diseases across Europe. The Journal of Hospital Infection. 81: 184-91. PMID 22648013 DOI: 10.1016/j.jhin.2012.04.019  0.52
2012 Schlenzig D, Rönicke R, Cynis H, Ludwig HH, Scheel E, Reymann K, Saido T, Hause G, Schilling S, Demuth HU. N-Terminal pyroglutamate formation of Aβ38 and Aβ40 enforces oligomer formation and potency to disrupt hippocampal long-term potentiation. Journal of Neurochemistry. 121: 774-84. PMID 22375951 DOI: 10.1111/j.1471-4159.2012.07707.x  0.52
2012 Frost JL, Liu B, Kleinschmidt M, Schilling S, Demuth HU, Lemere CA. Passive immunization against pyroglutamate-3 amyloid-β reduces plaque burden in Alzheimer-like transgenic mice: a pilot study. Neuro-Degenerative Diseases. 10: 265-70. PMID 22343072 DOI: 10.1159/000335913  0.52
2012 Wittnam JL, Portelius E, Zetterberg H, Gustavsson MK, Schilling S, Koch B, Demuth HU, Blennow K, Wirths O, Bayer TA. Pyroglutamate amyloid β (Aβ) aggravates behavioral deficits in transgenic amyloid mouse model for Alzheimer disease. The Journal of Biological Chemistry. 287: 8154-62. PMID 22267726 DOI: 10.1074/jbc.M111.308601  0.52
2012 Hillmann A, Hahn S, Schilling S, Hoffmann T, Demuth HU, Bulic B, Schneider-Axmann T, Bayer TA, Weggen S, Wirths O. No improvement after chronic ibuprofen treatment in the 5XFAD mouse model of Alzheimer's disease. Neurobiology of Aging. 33: 833.e39-50. PMID 21943956 DOI: 10.1016/j.neurobiolaging.2011.08.006  0.52
2011 Schilling SH. DNA as patentable subject matter and a narrow framework for addressing the perceived problems caused by gene patents. Duke Law Journal. 61: 731-73. PMID 22165443  0.52
2011 Alexandru A, Jagla W, Graubner S, Becker A, Bäuscher C, Kohlmann S, Sedlmeier R, Raber KA, Cynis H, Rönicke R, Reymann KG, Petrasch-Parwez E, Hartlage-Rübsamen M, Waniek A, Rossner S, ... Schilling S, et al. Selective hippocampal neurodegeneration in transgenic mice expressing small amounts of truncated Aβ is induced by pyroglutamate-Aβ formation. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 31: 12790-801. PMID 21900558 DOI: 10.1523/JNEUROSCI.1794-11.2011  0.52
2011 Cynis H, Hoffmann T, Friedrich D, Kehlen A, Gans K, Kleinschmidt M, Rahfeld JU, Wolf R, Wermann M, Stephan A, Haegele M, Sedlmeier R, Graubner S, Jagla W, Müller A, ... ... Schilling S, et al. The isoenzyme of glutaminyl cyclase is an important regulator of monocyte infiltration under inflammatory conditions. Embo Molecular Medicine. 3: 545-58. PMID 21774078 DOI: 10.1002/emmm.201100158  0.52
2011 Ruiz-Carrillo D, Koch B, Parthier C, Wermann M, Dambe T, Buchholz M, Ludwig HH, Heiser U, Rahfeld JU, Stubbs MT, Schilling S, Demuth HU. Structures of glycosylated mammalian glutaminyl cyclases reveal conformational variability near the active center. Biochemistry. 50: 6280-8. PMID 21671571 DOI: 10.1021/bi200249h  0.52
2011 Radiloff DR, Wakeman TP, Feng J, Schilling S, Seto E, Wang XF. Trefoil factor 1 acts to suppress senescence induced by oncogene activation during the cellular transformation process. Proceedings of the National Academy of Sciences of the United States of America. 108: 6591-6. PMID 21451135 DOI: 10.1073/pnas.1017269108  0.52
2011 Schilling S, Kohlmann S, Bäuscher C, Sedlmeier R, Koch B, Eichentopf R, Becker A, Cynis H, Hoffmann T, Berg S, Freyse EJ, von Hörsten S, Rossner S, Graubner S, Demuth HU. Glutaminyl cyclase knock-out mice exhibit slight hypothyroidism but no hypogonadism: implications for enzyme function and drug development. The Journal of Biological Chemistry. 286: 14199-208. PMID 21330373 DOI: 10.1074/jbc.M111.229385  0.52
2011 Hartlage-Rübsamen M, Morawski M, Waniek A, Jäger C, Zeitschel U, Koch B, Cynis H, Schilling S, Schliebs R, Demuth HU, Rossner S. Glutaminyl cyclase contributes to the formation of focal and diffuse pyroglutamate (pGlu)-Aβ deposits in hippocampus via distinct cellular mechanisms. Acta Neuropathologica. 121: 705-19. PMID 21301857 DOI: 10.1007/s00401-011-0806-2  0.52
2011 Jawhar S, Wirths O, Schilling S, Graubner S, Demuth HU, Bayer TA. Overexpression of glutaminyl cyclase, the enzyme responsible for pyroglutamate A{beta} formation, induces behavioral deficits, and glutaminyl cyclase knock-out rescues the behavioral phenotype in 5XFAD mice. The Journal of Biological Chemistry. 286: 4454-60. PMID 21148560 DOI: 10.1074/jbc.M110.185819  0.52
2010 Carrillo DR, Parthier C, Jänckel N, Grandke J, Stelter M, Schilling S, Boehme M, Neumann P, Wolf R, Demuth HU, Stubbs MT, Rahfeld JU. Kinetic and structural characterization of bacterial glutaminyl cyclases from Zymomonas mobilis and Myxococcus xanthus. Biological Chemistry. 391: 1419-28. PMID 20868223 DOI: 10.1515/BC.2010.130  0.52
2010 Tanghe A, Termont A, Merchiers P, Schilling S, Demuth HU, Scrocchi L, Van Leuven F, Griffioen G, Van Dooren T. Pathological Hallmarks, Clinical Parallels, and Value for Drug Testing in Alzheimer's Disease of the APP[V717I] London Transgenic Mouse Model. International Journal of Alzheimer's Disease. 2010. PMID 20862386 DOI: 10.4061/2010/417314  0.52
2010 Morawski M, Hartlage-Rübsamen M, Jäger C, Waniek A, Schilling S, Schwab C, McGeer PL, Arendt T, Demuth HU, Rossner S. Distinct glutaminyl cyclase expression in Edinger-Westphal nucleus, locus coeruleus and nucleus basalis Meynert contributes to pGlu-Abeta pathology in Alzheimer's disease. Acta Neuropathologica. 120: 195-207. PMID 20383514 DOI: 10.1007/s00401-010-0685-y  0.52
2009 Seifert F, Schulz K, Koch B, Manhart S, Demuth HU, Schilling S. Glutaminyl cyclases display significant catalytic proficiency for glutamyl substrates. Biochemistry. 48: 11831-3. PMID 19921850 DOI: 10.1021/bi9018835  0.52
2009 Buchholz M, Hamann A, Aust S, Brandt W, Böhme L, Hoffmann T, Schilling S, Demuth HU, Heiser U. Inhibitors for human glutaminyl cyclase by structure based design and bioisosteric replacement. Journal of Medicinal Chemistry. 52: 7069-80. PMID 19863057 DOI: 10.1021/jm900969p  0.52
2009 Stephan A, Wermann M, von Bohlen A, Koch B, Cynis H, Demuth HU, Schilling S. Mammalian glutaminyl cyclases and their isoenzymes have identical enzymatic characteristics. The Febs Journal. 276: 6522-36. PMID 19804409 DOI: 10.1111/j.1742-4658.2009.07337.x  0.52
2009 Hartlage-Rübsamen M, Staffa K, Waniek A, Wermann M, Hoffmann T, Cynis H, Schilling S, Demuth HU, Rossner S. Developmental expression and subcellular localization of glutaminyl cyclase in mouse brain. International Journal of Developmental Neuroscience : the Official Journal of the International Society For Developmental Neuroscience. 27: 825-35. PMID 19699792 DOI: 10.1016/j.ijdevneu.2009.08.007  0.52
2009 Schilling SH, Hjelmeland AB, Radiloff DR, Liu IM, Wakeman TP, Fielhauer JR, Foster EH, Lathia JD, Rich JN, Wang XF, Datto MB. NDRG4 is required for cell cycle progression and survival in glioblastoma cells. The Journal of Biological Chemistry. 284: 25160-9. PMID 19592488 DOI: 10.1074/jbc.M109.012484  0.52
2009 Wirths O, Breyhan H, Cynis H, Schilling S, Demuth HU, Bayer TA. Intraneuronal pyroglutamate-Abeta 3-42 triggers neurodegeneration and lethal neurological deficits in a transgenic mouse model. Acta Neuropathologica. 118: 487-96. PMID 19547991 DOI: 10.1007/s00401-009-0557-5  0.52
2009 Schlenzig D, Manhart S, Cinar Y, Kleinschmidt M, Hause G, Willbold D, Funke SA, Schilling S, Demuth HU. Pyroglutamate formation influences solubility and amyloidogenicity of amyloid peptides. Biochemistry. 48: 7072-8. PMID 19518051 DOI: 10.1021/bi900818a  0.52
2009 Bannister B, Prygodzicz A, Ippolito G, Gent N, Lloyd G, Zampieron A, Holmberg M, Georges MC, Schilling S, Brodt HR, Di Caro A. Training health care workers to face highly infectious diseases Clinical Microbiology and Infection. 15: 740-742. PMID 19486076 DOI: 10.1111/j.1469-0691.2009.02872.x  0.52
2009 Fusco FM, Schilling S, Puro V, Brodt HR, Follin P, Jarhall B, Bannister B, Maltezou HC, Thomson G, Brouqui P, Ippolito G. EuroNHID checklists for the assessment of high-level isolation units and referral centres for highly infectious diseases: results from the pilot phase of a European survey. Clinical Microbiology and Infection : the Official Publication of the European Society of Clinical Microbiology and Infectious Diseases. 15: 711-9. PMID 19486074 DOI: 10.1111/j.1469-0691.2009.02874.x  0.52
2009 Brouqui P, Puro V, Fusco FM, Bannister B, Schilling S, Follin P, Gottschalk R, Hemmer R, Maltezou HC, Ott K, Peleman R, Perronne C, Sheehan G, Siikamäki H, Skinhoj P, et al. Infection control in the management of highly pathogenic infectious diseases: consensus of the European Network of Infectious Disease. The Lancet. Infectious Diseases. 9: 301-11. PMID 19393960 DOI: 10.1016/S1473-3099(09)70070-2  0.52
2009 Jamai A, Salomé PA, Schilling SH, Weber AP, McClung CR. Arabidopsis photorespiratory serine hydroxymethyltransferase activity requires the mitochondrial accumulation of ferredoxin-dependent glutamate synthase. The Plant Cell. 21: 595-606. PMID 19223513 DOI: 10.1105/tpc.108.063289  0.52
2009 Liu IM, Schilling SH, Knouse KA, Choy L, Derynck R, Wang XF. TGFbeta-stimulated Smad1/5 phosphorylation requires the ALK5 L45 loop and mediates the pro-migratory TGFbeta switch. The Embo Journal. 28: 88-98. PMID 19096363 DOI: 10.1038/emboj.2008.266  0.52
2008 Schilling S, Wasternack C, Demuth HU. Glutaminyl cyclases from animals and plants: a case of functionally convergent protein evolution. Biological Chemistry. 389: 983-91. PMID 18979624 DOI: 10.1515/BC.2008.111  0.52
2008 Schilling S, Zeitschel U, Hoffmann T, Heiser U, Francke M, Kehlen A, Holzer M, Hutter-Paier B, Prokesch M, Windisch M, Jagla W, Schlenzig D, Lindner C, Rudolph T, Reuter G, et al. Glutaminyl cyclase inhibition attenuates pyroglutamate Aβ and Alzheimer's disease-like pathology Nature Medicine. 14: 1106-1111. PMID 18836460 DOI: 10.1038/nm.1872  0.52
2008 Schilling S, Appl T, Hoffmann T, Cynis H, Schulz K, Jagla W, Friedrich D, Wermann M, Buchholz M, Heiser U, von Hörsten S, Demuth HU. Inhibition of glutaminyl cyclase prevents pGlu-Abeta formation after intracortical/hippocampal microinjection in vivo/in situ. Journal of Neurochemistry. 106: 1225-36. PMID 18627432 DOI: 10.1111/j.1471-4159.2008.05471.x  0.52
2008 Cynis H, Scheel E, Saido TC, Schilling S, Demuth HU. Amyloidogenic processing of amyloid precursor protein: evidence of a pivotal role of glutaminyl cyclase in generation of pyroglutamate-modified amyloid-beta. Biochemistry. 47: 7405-13. PMID 18570439 DOI: 10.1021/bi800250p  0.52
2008 Cynis H, Rahfeld JU, Stephan A, Kehlen A, Koch B, Wermann M, Demuth HU, Schilling S. Isolation of an Isoenzyme of Human Glutaminyl Cyclase: Retention in the Golgi Complex Suggests Involvement in the Protein Maturation Machinery Journal of Molecular Biology. 379: 966-980. PMID 18486145 DOI: 10.1016/j.jmb.2008.03.078  0.52
2007 Schilling S, Lindner C, Koch B, Wermann M, Rahfeld JU, Von Bohlen A, Rudolph T, Reuter G, Demuth HU. Isolation and characterization of glutaminyl cyclases from Drosophila: Evidence for enzyme forms with different subcellular localization Biochemistry. 46: 10921-10930. PMID 17722885 DOI: 10.1021/bi701043x  0.52
2007 Schilling S, Stenzel I, von Bohlen A, Wermann M, Schulz K, Demuth HU, Wasternack C. Isolation and characterization of the glutaminyl cyclases from Solanum tuberosum and Arabidopsis thaliana: implications for physiological functions. Biological Chemistry. 388: 145-53. PMID 17261077 DOI: 10.1515/BC.2007.016  0.52
2006 Schilling S, Lauber T, Schaupp M, Manhart S, Scheel E, Böhm G, Demuth HU. On the seeding and oligomerization of pGlu-amyloid peptides (in vitro) Biochemistry. 45: 12393-12399. PMID 17029395 DOI: 10.1021/bi0612667  0.52
2006 Cynis H, Schilling S, Bodnár M, Hoffmann T, Heiser U, Saido TC, Demuth HU. Inhibition of glutaminyl cyclase alters pyroglutamate formation in mammalian cells. Biochimica Et Biophysica Acta. 1764: 1618-25. PMID 17005457 DOI: 10.1016/j.bbapap.2006.08.003  0.52
2006 Schilling SH, Datto MB, Wang XF. A phosphatase controls the fate of receptor-regulated Smads. Cell. 125: 838-40. PMID 16751094 DOI: 10.1016/j.cell.2006.05.015  0.52
2006 Buchholz M, Heiser U, Schilling S, Niestroj AJ, Zunkel K, Demuth HU. The first potent inhibitors for human glutaminyl cyclase: Synthesis and structure-activity relationship Journal of Medicinal Chemistry. 49: 664-677. PMID 16420052 DOI: 10.1021/jm050756e  0.52
2005 Balooch G, Balooch M, Nalla RK, Schilling S, Filvaroff EH, Marshall GW, Marshall SJ, Ritchie RO, Derynck R, Alliston T. TGF-beta regulates the mechanical properties and composition of bone matrix. Proceedings of the National Academy of Sciences of the United States of America. 102: 18813-8. PMID 16354837 DOI: 10.1073/pnas.0507417102  0.52
2005 Chow EK, O'connell RM, Schilling S, Wang XF, Fu XY, Cheng G. TLR agonists regulate PDGF-B production and cell proliferation through TGF-beta/type I IFN crosstalk. The Embo Journal. 24: 4071-81. PMID 16308570 DOI: 10.1038/sj.emboj.7600867  0.52
2005 Hjelmeland AB, Schilling SH, Guo X, Quarles D, Wang XF. Loss of Smad3-mediated negative regulation of Runx2 activity leads to an alteration in cell fate determination. Molecular and Cellular Biology. 25: 9460-8. PMID 16227596 DOI: 10.1128/MCB.25.21.9460-9468.2005  0.52
2005 Schilling S, Cynis H, Von Bohlen A, Hoffmann T, Wermann M, Heiser U, Buchholz M, Zunkel K, Demuth HU. Isolation, catalytic properties, and competitive inhibitors of the zinc-dependent murine glutaminyl cyclase Biochemistry. 44: 13415-13424. PMID 16201766 DOI: 10.1021/bi051142e  0.52
2004 Schilling S, Hoffmann T, Manhart S, Hoffmann M, Demuth HU. Glutaminyl cyclases unfold glutamyl cyclase activity under mild acid conditions Febs Letters. 563: 191-196. PMID 15063747 DOI: 10.1016/S0014-5793(04)00300-X  0.52
2004 Schilling S, Demuth HU. Continuous assays of glutaminyl cyclase: From development to application Spectroscopy. 18: 363-373.  0.52
2003 Schilling S, Manhart S, Hoffmann T, Ludwig HH, Wasternack C, Demuth HU. Substrate specificity of glutaminyl cyclases from plants and animals Biological Chemistry. 384: 1583-1592. PMID 14719800 DOI: 10.1515/BC.2003.175  0.52
2003 Schilling S, Niestroj AJ, Rahfeld JU, Hoffmann T, Wermann M, Zunkel K, Wasternack C, Demuth HU. Identification of human glutaminyl cyclase as a metalloenzyme: Potent inhibition by imidazole derivatives and heterocyclic chelators Journal of Biological Chemistry. 278: 49773-49779. PMID 14522962 DOI: 10.1074/jbc.M309077200  0.52
2003 Hardt R, Noack M, Santjer G, Schilling S, Hock G, Schöll K. Long-term evaluation of geriatric treatment: Results of a prospective study (Part 4: Patients with functional impairment associated with multimorbidity) European Journal of Geriatrics. 5: 132-136.  0.52
2002 Schilling S, Hoffmann T, Rosche F, Manhart S, Wasternack C, Demuth HU. Heterologous expression and characterization of human glutaminyl cyclase: Evidence for a disulfide bond with importance for catalytic activity Biochemistry. 41: 10849-10857. PMID 12196024 DOI: 10.1021/bi0260381  0.52
2002 Schilling S, Hoffmann T, Wermann M, Heiser U, Wasternack C, Demuth HU. Continuous spectrometric assays for glutaminyl cyclase activity Analytical Biochemistry. 303: 49-56. PMID 11906150 DOI: 10.1006/abio.2001.5560  0.52
2001 Schilling S, Glaichenhaus N. T cells that react to the immunodominant Leishmania major LACK antigen prevent early dissemination of the parasite in susceptible BALB/c mice Infection and Immunity. 69: 1212-1214. PMID 11160025 DOI: 10.1128/IAI.69.2.1212-1214.2001  0.52
2001 Hardt R, Noack M, Santjer G, Schilling S, Hock G, Schöll K. Long-term evaluation of geriatric treatment - Results of a prospective study (Part 3: Patients with centrally located diseases of the skeleton) European Journal of Geriatrics. 3: 186-191.  0.52
2000 Gottschalk R, Seidlt C, Schilling S, Braner A, Seifriedt E, Hoelzer D, Kaltwasser JP. Iron-overload and genotypic expression of HFE mutations H63D/C282Y and transferrin receptor Hin6I and BanI polymorphism in German patients with hereditary haemochromatosis European Journal of Immunogenetics. 27: 129-134. PMID 10940080 DOI: 10.1046/j.1365-2370.2000.00215.x  0.52
2000 Hardt R, Noack M, Santjer G, Schilling S, Hock G, Schöll K. Long-term evaluation of geriatric treatment - Results of a prospective study (Part 2: Patients with ischaemic stroke) European Journal of Geriatrics. 2: 128-134.  0.52
2000 Noack M, Schilling S, Santjer G, Hock G, Hardt R. Long-term evaluation of courses of geriatric treatment - Results of a prospective study (part 1) European Journal of Geriatrics. 2: 67-75.  0.52
1998 Schilling S, Pollmeier GK, Hardt R. Influencing factors and results of geriatric rehabilitation treatment | Einflussfaktoren und ergebnisse geriatrischer rehabilitation Geriatrie Forschung. 8: 123-126.  0.52
1991 Clemm C, Sauer H, Schilling S, Binsack T, Wilmanns W. Rehabilitation of patients with malignant germ cell tumor | Rehabilitation von Patienten mit malignem Keimzelltumor Versicherungsmedizin / Herausgegeben Von Verband Der Lebensversicherungs-Unternehmen E.V. Und Verband Der Privaten Krankenversicherung E.V. 43: 105-109. PMID 1659019  0.52
1989 Kahaly G, Grübl M, Moncayo R, Schilling S, Weber P, Beyer J, Krause U. Thyroid-stimulating and eye muscle antibodies in Graves' disease and Graves' orbitopathy Developments in Ophthalmology. 20: 68-78. PMID 2574117  0.52
1988 Kahaly G, Grubl M, Monayo R, Schilling S, Beyer J, Krause U. Thyrocyte-stimulating and ocular muscle antibodies in Graves' disease and endocrinal orbitopathy | THYREOZYTENSTIMULIERENDE UND AUGENMUSKELANTIKORPER BEI MORBUS BASEDOW UND ENDOKRINER ORBITOPATHIE Aktuelle Endokrinologie Und Stoffwechsel. 9: 22-26.  0.52
1985 Hirth L, Singh S, Schilling S, Müller E, Goedde HW. Dermatoglyphic findings in patients with fragile X-chromosome Clinical Genetics. 27: 118-121. PMID 3978845  0.52
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