Ratneshwar Lal - Publications

Affiliations: 
University of Chicago School of Medicine, North Chicago, IL, United States 

75 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2016 Jang H, Arce FT, Lee J, Gillman AL, Ramachandran S, Kagan BL, Lal R, Nussinov R. Computational Methods for Structural and Functional Studies of Alzheimer's Amyloid Ion Channels. Methods in Molecular Biology (Clifton, N.J.). 1345: 251-68. PMID 26453217 DOI: 10.1007/978-1-4939-2978-8_16  0.4
2015 Patel N, Ramachandran S, Azimov R, Kagan BL, Lal R. Ion Channel Formation by Tau Protein: Implications for Alzheimer's Disease and Taupathies. Biochemistry. PMID 26575330 DOI: 10.1021/acs.biochem.5b00988  0.4
2015 Hwang MT, Landon PB, Lee J, Mo A, Meckes B, Glinsky G, Lal R. DNA nano-carrier for repeatable capture and release of biomolecules. Nanoscale. PMID 26439640 DOI: 10.1039/c5nr05124j  0.4
2015 Landon PB, Mo AH, Printz AD, Emerson C, Zhang C, Janetanakit W, Colburn DA, Akkiraju S, Dossou S, Chong B, Glinsky G, Lal R. Asymmetric Colloidal Janus Particle Formation Is Core-Size-Dependent. Langmuir : the Acs Journal of Surfaces and Colloids. 31: 9148-54. PMID 26244597 DOI: 10.1021/acs.langmuir.5b01499  0.4
2015 Mo AH, Landon PB, Emerson CD, Zhang C, Anzenberg P, Akkiraju S, Lal R. Synthesis of nano-bowls with a Janus template. Nanoscale. 7: 771-5. PMID 25431230 DOI: 10.1039/c4nr05153j  0.4
2014 Fior R, Kwok J, Malfatti F, Sbaizero O, Lal R. Biocompatible Optically Transparent MEMS for Micromechanical Stimulation and Multimodal Imaging of Living Cells. Annals of Biomedical Engineering. PMID 25549773 DOI: 10.1007/s10439-014-1229-8  0.4
2014 Meckes B, Ambrosi C, Barnard H, Arce FT, Sosinsky GE, Lal R. Atomic force microscopy shows connexin26 hemichannel clustering in purified membrane fragments. Biochemistry. 53: 7407-14. PMID 25365227 DOI: 10.1021/bi501265p  0.4
2014 Landon PB, Lee J, Hwang MT, Mo AH, Zhang C, Neuberger A, Meckes B, Gutierrez JJ, Glinsky G, Lal R. Energetically biased DNA motor containing a thermodynamically stable partial strand displacement state. Langmuir : the Acs Journal of Surfaces and Colloids. 30: 14073-8. PMID 25347360 DOI: 10.1021/la503711g  0.4
2014 Alfonta L, Meckes B, Amir L, Schlesinger O, Ramachandran S, Lal R. Measuring localized redox enzyme electron transfer in a live cell with conducting atomic force microscopy. Analytical Chemistry. 86: 7674-80. PMID 24979064 DOI: 10.1021/ac5015645  0.4
2014 Kwok J, Grogan S, Meckes B, Arce F, Lal R, D'Lima D. Atomic force microscopy reveals age-dependent changes in nanomechanical properties of the extracellular matrix of native human menisci: implications for joint degeneration and osteoarthritis. Nanomedicine : Nanotechnology, Biology, and Medicine. 10: 1777-85. PMID 24972006 DOI: 10.1016/j.nano.2014.06.010  0.4
2014 Landon PB, Mo AH, Zhang C, Emerson CD, Printz AD, Gomez AF, DeLaTorre CJ, Colburn DA, Anzenberg P, Eliceiri M, O'Connell C, Lal R. Designing hollow nano gold golf balls. Acs Applied Materials & Interfaces. 6: 9937-41. PMID 24937196 DOI: 10.1021/am502519x  0.4
2014 Meckes B, Arce FT, Connelly LS, Lal R. Insulated conducting cantilevered nanotips and two-chamber recording system for high resolution ion sensing AFM. Scientific Reports. 4: 4454. PMID 24663394 DOI: 10.1038/srep04454  0.4
2014 Ramachandran S, Arce FT, Patel NR, Quist AP, Cohen DA, Lal R. Structure and permeability of ion-channels by integrated AFM and waveguide TIRF microscopy. Scientific Reports. 4: 4424. PMID 24651823 DOI: 10.1038/srep04424  0.4
2014 Connelly LS, Meckes B, Larkin J, Gillman AL, Wanunu M, Lal R. Graphene nanopore support system for simultaneous high-resolution AFM imaging and conductance measurements. Acs Applied Materials & Interfaces. 6: 5290-6. PMID 24581087 DOI: 10.1021/am500639q  0.4
2014 Jang H, Arce FT, Ramachandran S, Kagan BL, Lal R, Nussinov R. Disordered amyloidogenic peptides may insert into the membrane and assemble into common cyclic structural motifs. Chemical Society Reviews. 43: 6750-64. PMID 24566672 DOI: 10.1039/c3cs60459d  0.4
2014 Mo AH, Landon PB, Meckes B, Yang MM, Glinsky GV, Lal R. An on-demand four-way junction DNAzyme nanoswitch driven by inosine-based partial strand displacement. Nanoscale. 6: 1462-6. PMID 24317092 DOI: 10.1039/c3nr05365b  0.4
2013 Jang H, Arce FT, Ramachandran S, Kagan BL, Lal R, Nussinov R. Familial Alzheimer's disease Osaka mutant (ΔE22) β-barrels suggest an explanation for the different Aβ1-40/42 preferred conformational states observed by experiment. The Journal of Physical Chemistry. B. 117: 11518-29. PMID 24000923 DOI: 10.1021/jp405389n  0.4
2013 Arce FT, Meckes B, Camp SM, Garcia JG, Dudek SM, Lal R. Heterogeneous elastic response of human lung microvascular endothelial cells to barrier modulating stimuli. Nanomedicine : Nanotechnology, Biology, and Medicine. 9: 875-84. PMID 23523769 DOI: 10.1016/j.nano.2013.03.006  0.4
2013 Jang H, Connelly L, Arce FT, Ramachandran S, Lal R, Kagan BL, Nussinov R. Alzheimer's disease: which type of amyloid-preventing drug agents to employ? Physical Chemistry Chemical Physics : Pccp. 15: 8868-77. PMID 23450150 DOI: 10.1039/c3cp00017f  0.4
2013 Jang H, Connelly L, Arce FT, Ramachandran S, Kagan BL, Lal R, Nussinov R. Mechanisms for the Insertion of Toxic, Fibril-like β-Amyloid Oligomers into the Membrane. Journal of Chemical Theory and Computation. 9: 822-833. PMID 23316126 DOI: 10.1021/ct300916f  0.4
2012 Kong SD, Lee J, Ramachandran S, Eliceiri BP, Shubayev VI, Lal R, Jin S. Magnetic targeting of nanoparticles across the intact blood-brain barrier. Journal of Controlled Release : Official Journal of the Controlled Release Society. 164: 49-57. PMID 23063548 DOI: 10.1016/j.jconrel.2012.09.021  0.4
2012 Capone R, Jang H, Kotler SA, Connelly L, Teran Arce F, Ramachandran S, Kagan BL, Nussinov R, Lal R. All-d-Enantiomer of β-Amyloid Peptide Forms Ion Channels in Lipid Bilayers. Journal of Chemical Theory and Computation. 8: 1143-1152. PMID 22423218 DOI: 10.1021/ct200885r  0.4
2012 Connelly L, Jang H, Arce FT, Ramachandran S, Kagan BL, Nussinov R, Lal R. Effects of point substitutions on the structure of toxic Alzheimer's β-amyloid channels: atomic force microscopy and molecular dynamics simulations. Biochemistry. 51: 3031-8. PMID 22413858 DOI: 10.1021/bi300257e  0.4
2012 Capone R, Jang H, Kotler SA, Kagan BL, Nussinov R, Lal R. Probing structural features of Alzheimer's amyloid-β pores in bilayers using site-specific amino acid substitutions. Biochemistry. 51: 776-85. PMID 22242635 DOI: 10.1021/bi2017427  0.4
2012 Connelly L, Jang H, Arce FT, Capone R, Kotler SA, Ramachandran S, Kagan BL, Nussinov R, Lal R. Atomic force microscopy and MD simulations reveal pore-like structures of all-D-enantiomer of Alzheimer's β-amyloid peptide: relevance to the ion channel mechanism of AD pathology. The Journal of Physical Chemistry. B. 116: 1728-35. PMID 22217000 DOI: 10.1021/jp2108126  0.4
2012 Kagan BL, Jang H, Capone R, Teran Arce F, Ramachandran S, Lal R, Nussinov R. Antimicrobial properties of amyloid peptides. Molecular Pharmaceutics. 9: 708-17. PMID 22081976 DOI: 10.1021/mp200419b  0.4
2012 Allen MJ, Lacroix JJ, Ramachandran S, Capone R, Whitlock JL, Ghadge GD, Arnsdorf MF, Roos RP, Lal R. Mutant SOD1 forms ion channel: implications for ALS pathophysiology. Neurobiology of Disease. 45: 831-8. PMID 21930207 DOI: 10.1016/j.nbd.2011.08.031  0.4
2012 Landon PB, Ramachandran S, Gillman A, Gidron T, Yoon D, Lal R. DNA zipper-based tweezers. Langmuir : the Acs Journal of Surfaces and Colloids. 28: 534-40. PMID 21875130 DOI: 10.1021/la201267e  0.4
2011 Arce FT, Jang H, Ramachandran S, Landon PB, Nussinov R, Lal R. Polymorphism of amyloid β peptide in different environments: implications for membrane insertion and pore formation. Soft Matter. 7: 5267-5273. PMID 21918653 DOI: 10.1039/C1SM05162H  0.4
2011 Jang H, Arce FT, Mustata M, Ramachandran S, Capone R, Nussinov R, Lal R. Antimicrobial protegrin-1 forms amyloid-like fibrils with rapid kinetics suggesting a functional link. Biophysical Journal. 100: 1775-83. PMID 21463591 DOI: 10.1016/j.bpj.2011.01.072  0.4
2011 Ayala R, Zhang C, Yang D, Hwang Y, Aung A, Shroff SS, Arce FT, Lal R, Arya G, Varghese S. Engineering the cell-material interface for controlling stem cell adhesion, migration, and differentiation. Biomaterials. 32: 3700-11. PMID 21396708 DOI: 10.1016/j.biomaterials.2011.02.004  0.4
2010 Kong SD, Zhang W, Lee JH, Brammer K, Lal R, Karin M, Jin S. Magnetically vectored nanocapsules for tumor penetration and remotely switchable on-demand drug release. Nano Letters. 10: 5088-92. PMID 21038917 DOI: 10.1021/nl1033733  0.4
2010 Jang H, Arce FT, Ramachandran S, Capone R, Lal R, Nussinov R. β-Barrel topology of Alzheimer's β-amyloid ion channels. Journal of Molecular Biology. 404: 917-34. PMID 20970427 DOI: 10.1016/j.jmb.2010.10.025  0.4
2010 Dudek SM, Chiang ET, Camp SM, Guo Y, Zhao J, Brown ME, Singleton PA, Wang L, Desai A, Arce FT, Lal R, Van Eyk JE, Imam SZ, Garcia JG. Abl tyrosine kinase phosphorylates nonmuscle Myosin light chain kinase to regulate endothelial barrier function. Molecular Biology of the Cell. 21: 4042-56. PMID 20861316 DOI: 10.1091/mbc.E09-10-0876  0.4
2010 Capone R, Mustata M, Jang H, Arce FT, Nussinov R, Lal R. Antimicrobial protegrin-1 forms ion channels: molecular dynamic simulation, atomic force microscopy, and electrical conductance studies. Biophysical Journal. 98: 2644-52. PMID 20513409 DOI: 10.1016/j.bpj.2010.02.024  0.4
2010 Jang H, Arce FT, Ramachandran S, Capone R, Azimova R, Kagan BL, Nussinov R, Lal R. Truncated beta-amyloid peptide channels provide an alternative mechanism for Alzheimer's Disease and Down syndrome. Proceedings of the National Academy of Sciences of the United States of America. 107: 6538-43. PMID 20308552 DOI: 10.1073/pnas.0914251107  0.4
2009 Jang H, Arce FT, Capone R, Ramachandran S, Lal R, Nussinov R. Misfolded amyloid ion channels present mobile beta-sheet subunits in contrast to conventional ion channels. Biophysical Journal. 97: 3029-37. PMID 19948133 DOI: 10.1016/j.bpj.2009.09.014  0.4
2009 Mustata M, Capone R, Jang H, Arce FT, Ramachandran S, Lal R, Nussinov R. K3 fragment of amyloidogenic beta(2)-microglobulin forms ion channels: implication for dialysis related amyloidosis. Journal of the American Chemical Society. 131: 14938-45. PMID 19824733 DOI: 10.1021/ja9049299  0.4
2009 Shen HM, Poirier MG, Allen MJ, North J, Lal R, Widom J, Storb U. The activation-induced cytidine deaminase (AID) efficiently targets DNA in nucleosomes but only during transcription. The Journal of Experimental Medicine. 206: 1057-71. PMID 19380635 DOI: 10.1084/jem.20082678  0.4
2009 Arce FT, Carlson R, Monds J, Veeh R, Hu FZ, Stewart PS, Lal R, Ehrlich GD, Avci R. Nanoscale structural and mechanical properties of nontypeable Haemophilus influenzae biofilms. Journal of Bacteriology. 191: 2512-20. PMID 19218382 DOI: 10.1128/JB.01596-08  0.4
2009 Birukova AA, Arce FT, Moldobaeva N, Dudek SM, Garcia JG, Lal R, Birukov KG. Endothelial permeability is controlled by spatially defined cytoskeletal mechanics: atomic force microscopy force mapping of pulmonary endothelial monolayer. Nanomedicine : Nanotechnology, Biology, and Medicine. 5: 30-41. PMID 18824415 DOI: 10.1016/j.nano.2008.07.002  0.4
2008 Arce FT, Whitlock JL, Birukova AA, Birukov KG, Arnsdorf MF, Lal R, Garcia JG, Dudek SM. Regulation of the micromechanical properties of pulmonary endothelium by S1P and thrombin: role of cortactin. Biophysical Journal. 95: 886-94. PMID 18408039 DOI: 10.1529/biophysj.107.127167  0.4
2003 Makrides V, Shen TE, Bhatia R, Smith BL, Thimm J, Lal R, Feinstein SC. Microtubule-dependent oligomerization of tau. Implications for physiological tau function and tauopathies. The Journal of Biological Chemistry. 278: 33298-304. PMID 12805366 DOI: 10.1074/jbc.M305207200  1
2003 Ionescu-Zanetti C, Cheung K, Lal R, Lee LP. Simultaneous imaging of ionic conductivity and morphology of a microfluidic system Journal of Applied Physics. 93: 10134-10136. DOI: 10.1063/1.1576297  1
2002 Parbhu A, Lin H, Thimm J, Lal R. Imaging real-time aggregation of amyloid beta protein (1-42) by atomic force microscopy. Peptides. 23: 1265-70. PMID 12128083 DOI: 10.1016/S0196-9781(02)00061-X  1
2001 Lin H, Bhatia R, Lal R. Amyloid β protein forms ion channels: Implications for Alzheimer's disease pathophysiology Faseb Journal. 15: 2433-2444. PMID 11689468 DOI: 10.1096/fj.01-0377com  1
2001 Lal R, Lin H. Imaging molecular structure and physiological function of gap junctions and hemijunctions by multimodal atomic force microscopy Microscopy Research and Technique. 52: 273-288. PMID 11180620 DOI: 10.1002/1097-0029(20010201)52:3<273::AID-JEMT1013>3.0.CO;2-M  1
2000 Zhu YJ, Lin H, Lal R. Fresh and nonfibrillar amyloid β protein(1-40) induces rapid cellular degeneration in aged human fibroblasts: Evidence for AβP-channel-mediated cellular toxicity Faseb Journal. 14: 1244-1254. PMID 10834946  1
2000 Bhatia R, Lin H, Lal R. Fresh and globular amyloid β protein (1-42) induces rapid cellular degeneration: Evidence for AβP channel-mediated cellular toxicity Faseb Journal. 14: 1233-1243. PMID 10834945  1
2000 Quist AP, Rhee SK, Lin H, Lal R. Physiological role of gap-junctional hemichannels: Extracellular calcium-dependent isosmotic volume regulation Journal of Cell Biology. 148: 1063-1074. PMID 10704454 DOI: 10.1083/jcb.148.5.1063  1
2000 Kim H, Garavito RM, Lal R. Atomic force microscopy of the three-dimensional crystal of membrane protein, OmpC porin Colloids and Surfaces B: Biointerfaces. 19: 347-355. DOI: 10.1016/S0927-7765(00)00143-0  1
1999 Parbhu AN, Bryson WG, Lal R. Disulfide bonds in the outer layer of keratin fibers confer higher mechanical rigidity: Correlative nano-indentation and elasticity measurement with an AFM Biochemistry. 38: 11755-11761. PMID 10512632 DOI: 10.1021/bi990746d  1
1999 Lin H, Zhu YJ, Lal R. Amyloid β protein (1-40) forms calcium-permeable, Zn2+-sensitive channel in reconstituted lipid vesicles Biochemistry. 38: 11189-11196. PMID 10460176 DOI: 10.1021/bi982997c  1
1998 Rhee SK, Quist AP, Lal R. Amyloid β protein-(1-42) forms calcium-permeable, Zn2+-sensitive channel Journal of Biological Chemistry. 273: 13379-13382. PMID 9593665 DOI: 10.1074/jbc.273.22.13379  1
1997 John SA, Saner D, Pitts JD, Holzenburg A, Finbow ME, Lal R. Atomic force microscopy of arthropod gap junctions Journal of Structural Biology. 120: 22-31. PMID 9356288 DOI: 10.1006/jsbi.1997.3893  1
1997 Lal R, Proksch R. Multimodal atomic force microscopy: Biological imaging using atomic force microscopy combined with light fluorescence and confocal microscopies and electrophysiologic recording International Journal of Imaging Systems and Technology. 8: 293-300.  1
1996 Lal R. Imaging molecular structure of channels and receptors with an atomic force microscope Scanning Microscopy. Supplement. 10: 81-95; discussion 95. PMID 9601532  1
1995 Barbee KA, Mundel T, Lal R, Davies PF. Subcellular distribution of shear stress at the surface of flow-aligned and nonaligned endothelial monolayers American Journal of Physiology - Heart and Circulatory Physiology. 268: H1765-H1772. PMID 7733381  1
1995 Lal R, John SA, Laird DW, Arnsdorf MF. Heart gap junction preparations reveal hemiplaques by atomic force microscopy American Journal of Physiology - Cell Physiology. 268: C968-C977. PMID 7733245  1
1995 Davies PF, Barbee KA, Lal R, Robotewskyj A, Griem ML. Hemodynamics and atherogenesis. Endothelial surface dynamics in flow signal transduction Annals of the New York Academy of Sciences. 748: 86-103. PMID 7695226  1
1995 Lal R, Drake B, Blumberg D, Saner DR, Hansma PK, Feinstein SC. Imaging real-time neurite outgrowth and cytoskeletal reorganization with an atomic force microscope. The American Journal of Physiology. 269: C275-85. PMID 7631755  1
1995 Blair JM, Sorensen LB, Arnsdorf MF, Lal R. The application of atomic force microscopy for the detection of microcrystals in synovial fluid from patients with recurrent synovitis Seminars in Arthritis and Rheumatism. 24: 359-369. PMID 7604301 DOI: 10.1016/S0049-0172(95)80005-0  1
1994 Barbee KA, Davies PF, Lal R. Shear stress-induced reorganization of the surface topography of living endothelial cells imaged by atomic force microscopy Circulation Research. 74: 163-171. PMID 8261591  1
1994 Barbee KA, Mundel T, Lal R, Davies PF. Distribution of shear stress on the surface of aligned and non-aligned endothelial monolayers American Society of Mechanical Engineers, Bioengineering Division (Publication) Bed. 28: 349-350.  1
1993 Polacek D, Lal R, Volin MV, Davies PF. Gap junctional communication between vascular cells: Induction of connexin43 messenger RNA in macrophage foam cells of atherosclerotic lesions American Journal of Pathology. 142: 593-606. PMID 8382009  1
1993 Lal R, Kim H, Garavito RM, Arnsdorf MF. Imaging of reconstituted biological channels at molecular resolution by atomic force microscopy. The American Journal of Physiology. 265: C851-6. PMID 8214041  1
1993 Lal R, Yu L. Atomic force microscopy of cloned nicotinic acetylcholine receptor expressed in Xenopus oocytes Proceedings of the National Academy of Sciences of the United States of America. 90: 7280-7284. PMID 7688475  1
1993 Lal R, Laird DW, Revel JP. Antibody perturbation analysis of gap-junction permeability in rat cardiac myocytes. PflüGers Archiv : European Journal of Physiology. 422: 449-57. PMID 7682685 DOI: 10.1007/BF00375070  1
1992 Lal R, Arnsdorf MF. Voltage-dependent gating and single-channel conductance of adult mammalian atrial gap junctions Circulation Research. 71: 737-743. PMID 1499115  1
1992 Arnsdorf MFMD, Lal R. Recent progress with atomic-force microscopy in biology: molecular resolution imaging of cell membranes, constituent biomolecules, and microcrystals Proceedings of Spie - the International Society For Optical Engineering. 1778: 112-116.  1
1991 Hoh JH, Lal R, John SA, Revel JP, Arnsdorf MF. Atomic force microscopy and dissection of gap junctions. Science (New York, N.Y.). 253: 1405-8. PMID 1910206  1
1990 Lal R, Friedlander MJ. Effect of passive eye movement on retinogeniculate transmission in the cat. Journal of Neurophysiology. 63: 523-38. PMID 2329359  1
1990 Lal R, Friedlander MJ. Effect of passive eye position changes on retinogeniculate transmission in the cat. Journal of Neurophysiology. 63: 502-22. PMID 2329358  1
1989 Lal R, Friedlander MJ. Gating of retinal transmission by afferent eye position and movement signals. Science (New York, N.Y.). 243: 93-6. PMID 2911723  1
1989 Yancey SB, John SA, Lal R, Austin BJ, Revel JP. The 43-kD polypeptide of heart gap junctions: immunolocalization, topology, and functional domains. The Journal of Cell Biology. 108: 2241-54. PMID 2472402  1
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