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Kara A. Bernstein, Ph.D. - Publications

Affiliations: 
2006 Yale University, New Haven, CT 
Area:
ribosomes
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50 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Wan L, Toland S, Robinson-McCarthy LR, Lee N, Schaich MA, Hengel SR, Li X, Bernstein KA, Van Houten B, Chang Y, Moore PS. Unlicensed origin DNA melting by MCV and SV40 polyomavirus LT proteins is independent of ATP-dependent helicase activity. Proceedings of the National Academy of Sciences of the United States of America. 120: e2308010120. PMID 37459531 DOI: 10.1073/pnas.2308010120  0.344
2023 Rawal Y, Jia L, Meir A, Zhou S, Kaur H, Ruben EA, Kwon Y, Bernstein KA, Jasin M, Taylor AB, Burma S, Hromas R, Mazin AV, Zhao W, Zhou D, et al. Structural insights into BCDX2 complex function in homologous recombination. Nature. PMID 37344589 DOI: 10.1038/s41586-023-06219-w  0.345
2022 Luong TT, Li Z, Priedigkeit N, Parker PS, Böhm S, Rapchak K, Lee AV, Bernstein KA. Hrq1/RECQL4 regulation is critical for preventing aberrant recombination during DNA intrastrand crosslink repair and is upregulated in breast cancer. Plos Genetics. 18: e1010122. PMID 36126066 DOI: 10.1371/journal.pgen.1010122  0.396
2022 Prakash R, Rawal Y, Sullivan MR, Grundy MK, Bret H, Mihalevic MJ, Rein HL, Baird JM, Darrah K, Zhang F, Wang R, Traina TA, Radke MR, Kaufmann SH, Swisher EM, ... ... Bernstein KA, et al. Homologous recombination-deficient mutation cluster in tumor suppressor identified by comprehensive analysis of cancer variants. Proceedings of the National Academy of Sciences of the United States of America. 119: e2202727119. PMID 36099300 DOI: 10.1073/pnas.2202727119  0.301
2021 Luong TT, Bernstein KA. Role and Regulation of the RECQL4 Family during Genomic Integrity Maintenance. Genes. 12. PMID 34946868 DOI: 10.3390/genes12121919  0.354
2021 Bonilla B, Brown AI, Hengel SR, Rapchak KS, Mitchell D, Pressimone CA, Fagunloye AA, Luong TT, Russell RA, Vyas RK, Mertz TM, Zaher HS, Mosammaparast N, Malc EP, Mieczkowski PA, ... ... Bernstein KA, et al. The Shu complex prevents mutagenesis and cytotoxicity of single-strand specific alkylation lesions. Elife. 10. PMID 34723799 DOI: 10.7554/eLife.68080  0.368
2021 Rein HL, Bernstein KA, Baldock RA. RAD51 paralog function in replicative DNA damage and tolerance. Current Opinion in Genetics & Development. 71: 86-91. PMID 34311385 DOI: 10.1016/j.gde.2021.06.010  0.343
2021 Prakash R, Sandoval T, Morati F, Zagelbaum JA, Lim PX, White T, Taylor B, Wang R, Desclos ECB, Sullivan MR, Rein HL, Bernstein KA, Krawczyk PM, Gautier J, Modesti M, et al. Distinct pathways of homologous recombination controlled by the SWS1-SWSAP1-SPIDR complex. Nature Communications. 12: 4255. PMID 34253720 DOI: 10.1038/s41467-021-24205-6  0.377
2020 Bonilla B, Hengel SR, Grundy MK, Bernstein KA. Gene Family Structure and Function. Annual Review of Genetics. PMID 32663049 DOI: 10.1146/Annurev-Genet-021920-092410  0.422
2020 Huang JW, Acharya A, Taglialatela A, Nambiar TS, Cuella-Martin R, Leuzzi G, Hayward SB, Joseph SA, Brunette GJ, Anand R, Soni RK, Clark NL, Bernstein KA, Cejka P, Ciccia A. MCM8IP activates the MCM8-9 helicase to promote DNA synthesis and homologous recombination upon DNA damage. Nature Communications. 11: 2948. PMID 32528060 DOI: 10.1038/S41467-020-16718-3  0.473
2019 Martino J, Brunette GJ, Barroso-González J, Moiseeva TN, Smith CM, Bakkenist CJ, O'Sullivan RJ, Bernstein KA. The human Shu complex functions with PDS5B and SPIDR to promote homologous recombination. Nucleic Acids Research. 47: 10151-10165. PMID 31665741 DOI: 10.1093/Nar/Gkz738  0.483
2019 Garcin EB, Gon S, Sullivan MR, Brunette GJ, Cian A, Concordet JP, Giovannangeli C, Dirks WG, Eberth S, Bernstein KA, Prakash R, Jasin M, Modesti M. Differential Requirements for the RAD51 Paralogs in Genome Repair and Maintenance in Human Cells. Plos Genetics. 15: e1008355. PMID 31584931 DOI: 10.1371/Journal.Pgen.1008355  0.445
2019 Brunette GJ, Jamalruddin MA, Baldock RA, Clark NL, Bernstein KA. Evolution-based screening enables genome-wide prioritization and discovery of DNA repair genes. Proceedings of the National Academy of Sciences of the United States of America. PMID 31501324 DOI: 10.1073/Pnas.1906559116  0.397
2019 Barroso-González J, García-Expósito L, Hoang SM, Lynskey ML, Roncaioli JL, Ghosh A, Wallace CT, Modesti M, Bernstein KA, Sarkar SN, Watkins SC, O'Sullivan RJ. RAD51AP1 Is an Essential Mediator of Alternative Lengthening of Telomeres. Molecular Cell. PMID 31400850 DOI: 10.1016/J.Molcel.2019.06.043  0.494
2019 Rosenbaum JC, Bonilla B, Hengel SR, Mertz TM, Herken BW, Kazemier HG, Pressimone CA, Ratterman TC, MacNary E, De Magis A, Kwon Y, Godin SK, Van Houten B, Normolle DP, Sung P, ... ... Bernstein KA, et al. The Rad51 paralogs facilitate a novel DNA strand specific damage tolerance pathway. Nature Communications. 10: 3515. PMID 31383866 DOI: 10.1038/S41467-019-11374-8  0.47
2019 Baldock RA, Pressimone CA, Baird JM, Khodakov A, Luong TT, Grundy MK, Smith CM, Karpenshif Y, Bratton-Palmer DS, Prakash R, Jasin M, Garcin EB, Gon S, Modesti M, Bernstein KA. RAD51D splice variants and cancer-associated mutations reveal XRCC2 interaction to be critical for homologous recombination. Dna Repair. 76: 99-107. PMID 30836272 DOI: 10.1016/J.Dnarep.2019.02.008  0.436
2019 Baldock RA, Pressimone CA, Baird JM, Khodakov AY, Karpenshif Y, Garcin EB, Gon S, Modesti M, Bernstein KA. Abstract AP05: OVARIAN CANCER-ASSOCIATED RAD51D MUTATIONS WHICH IMPAIR ITS INTERACTION WITH XRCC2 RESULT IN DNA REPAIR DEFICIENCY Clinical Cancer Research. 25. DOI: 10.1158/1557-3265.Ovcasymp18-Ap05  0.416
2018 Sullivan MR, Bernstein KA. RAD-ical New Insights into RAD51 Regulation. Genes. 9. PMID 30551670 DOI: 10.3390/Genes9120629  0.475
2017 Westmoreland JW, Mihalevic MJ, Bernstein KA, Resnick MA. The global role for Cdc13 and Yku70 in preventing telomere resection across the genome. Dna Repair. 62: 8-17. PMID 29247743 DOI: 10.1016/J.Dnarep.2017.11.010  0.318
2017 Varlakhanova NV, Mihalevic M, Bernstein KA, Ford MGJ. Pib2 and EGO Complex are both required for activation of TORC1. Journal of Cell Science. PMID 28993463 DOI: 10.1242/Jcs.207910  0.329
2017 Zacchi LF, Dittmar JC, Mihalevic MJ, Shewan AM, Schulz BL, Brodsky JL, Bernstein KA. A novel high-throughput yeast genetic screen for factors modifying protein levels of the Early-Onset Torsion Dystonia-associated variant torsinAΔE. Disease Models & Mechanisms. PMID 28768697 DOI: 10.1242/Dmm.029926  0.401
2017 Kondrashova O, Nguyen M, Shield-Artin K, Tinker AV, Teng NNH, Harrell MI, Kuiper MJ, Ho GY, Barker H, Jasin M, Prakash R, Kass EM, Sullivan MR, Brunette GJ, Bernstein KA, et al. Secondary Somatic Mutations Restoring RAD51C and RAD51D Associated with Acquired Resistance to the PARP Inhibitor Rucaparib in High-grade Ovarian Carcinoma. Cancer Discovery. PMID 28588062 DOI: 10.1158/2159-8290.Cd-17-0419  0.35
2017 Sullivan MR, Prakash R, Jasin M, Bernstein KA. Abstract A10: The impact of cancer-associated RAD51C mutations in homologous recombination Molecular Cancer Research. 15. DOI: 10.1158/1557-3125.Dnarepair16-A10  0.471
2016 Kong M, Liu L, Chen X, Driscoll KI, Mao P, Böhm S, Kad NM, Watkins SC, Bernstein KA, Wyrick JJ, Min JH, Van Houten B. Single-Molecule Imaging Reveals that Rad4 Employs a Dynamic DNA Damage Recognition Process. Molecular Cell. PMID 27720644 DOI: 10.1016/J.Molcel.2016.09.005  0.402
2016 Martino J, Bernstein KA. The Shu complex is a conserved regulator of homologous recombination. Fems Yeast Research. PMID 27589940 DOI: 10.1093/Femsyr/Fow073  0.471
2016 Godin SK, Zhang Z, Herken BW, Westmoreland JW, Lee AG, Mihalevic MJ, Yu Z, Sobol RW, Resnick MA, Bernstein KA. The Shu complex promotes error-free tolerance of alkylation-induced base excision repair products. Nucleic Acids Research. PMID 27298254 DOI: 10.1093/Nar/Gkw535  0.411
2016 Godin SK, Sullivan MR, Bernstein KA. Novel insights into RAD51 activity and regulation during homologous recombination and DNA replication. Biochemistry and Cell Biology = Biochimie Et Biologie Cellulaire. 1-12. PMID 27224545 DOI: 10.1139/Bcb-2016-0012  0.463
2016 McClendon TB, Sullivan M, Bernstein K, Yanowitz J. Promotion of Homologous Recombination by SWS-1 in Complex with RAD-51 Paralogs in Caenorhabditis elegans. Genetics. PMID 26936927 DOI: 10.1534/Genetics.115.185827  0.469
2016 Godin SK, Lee AG, Baird JM, Herken BW, Bernstein KA. Tryptophan biosynthesis is important for resistance to replicative stress in Saccharomyces cerevisiae. Yeast (Chichester, England). PMID 26804060 DOI: 10.1002/Yea.3150  0.426
2016 Böhm S, Szakal B, Herken BW, Sullivan MR, Mihalevic MJ, Kabbinavar FF, Branzei D, Clark NL, Bernstein KA. The Budding Yeast Ubiquitin Protease Ubp7 is a Novel Component Involved in S-phase Progression. The Journal of Biological Chemistry. PMID 26740628 DOI: 10.1074/Jbc.M115.671057  0.448
2015 Gaines WA, Godin SK, Kabbinavar FF, Rao T, VanDemark AP, Sung P, Bernstein KA. Promotion of presynaptic filament assembly by the ensemble of S. cerevisiae Rad51 paralogues with Rad52. Nature Communications. 6: 7834. PMID 26215801 DOI: 10.1038/Ncomms8834  0.468
2015 Wei L, Nakajima S, Böhm S, Bernstein KA, Shen Z, Tsang M, Levine AS, Lan L. DNA damage during the G0/G1 phase triggers RNA-templated, Cockayne syndrome B-dependent homologous recombination. Proceedings of the National Academy of Sciences of the United States of America. 112: E3495-504. PMID 26100862 DOI: 10.1073/Pnas.1507105112  0.443
2015 Godin SK, Meslin C, Kabbinavar F, Bratton-Palmer DS, Hornack C, Mihalevic MJ, Yoshida K, Sullivan M, Clark NL, Bernstein KA. Evolutionary and functional analysis of the invariant SWIM domain in the conserved Shu2/SWS1 protein family from Saccharomyces cerevisiae to Homo sapiens. Genetics. 199: 1023-33. PMID 25659377 DOI: 10.1534/Genetics.114.173518  0.447
2015 Böhm S, Mihalevic MJ, Casal MA, Bernstein KA. Disruption of SUMO-targeted ubiquitin ligases Slx5-Slx8/RNF4 alters RecQ-like helicase Sgs1/BLM localization in yeast and human cells. Dna Repair. 26: 1-14. PMID 25588990 DOI: 10.1016/J.Dnarep.2014.12.004  0.511
2014 Böhm S, Bernstein KA. The role of post-translational modifications in fine-tuning BLM helicase function during DNA repair. Dna Repair. 22: 123-32. PMID 25150915 DOI: 10.1016/J.Dnarep.2014.07.007  0.513
2014 Fu Q, Chow J, Bernstein KA, Makharashvili N, Arora S, Lee CF, Person MD, Rothstein R, Paull TT. Phosphorylation-regulated transitions in an oligomeric state control the activity of the Sae2 DNA repair enzyme. Molecular and Cellular Biology. 34: 778-93. PMID 24344201 DOI: 10.1128/Mcb.00963-13  0.452
2013 Bernstein KA, Mimitou EP, Mihalevic MJ, Chen H, Sunjaveric I, Symington LS, Rothstein R. Resection activity of the Sgs1 helicase alters the affinity of DNA ends for homologous recombination proteins in Saccharomyces cerevisiae. Genetics. 195: 1241-51. PMID 24097410 DOI: 10.1534/Genetics.113.157370  0.479
2013 Bernstein KA, Juanchich A, Sunjevaric I, Rothstein R. The Shu complex regulates Rad52 localization during rDNA repair. Dna Repair. 12: 786-90. PMID 23790361 DOI: 10.1016/J.Dnarep.2013.05.003  0.513
2013 Godin S, Wier A, Kabbinavar F, Bratton-Palmer DS, Ghodke H, Van Houten B, VanDemark AP, Bernstein KA. The Shu complex interacts with Rad51 through the Rad51 paralogues Rad55-Rad57 to mediate error-free recombination. Nucleic Acids Research. 41: 4525-34. PMID 23460207 DOI: 10.1093/Nar/Gkt138  0.44
2012 Karpenshif Y, Bernstein KA. From yeast to mammals: recent advances in genetic control of homologous recombination. Dna Repair. 11: 781-8. PMID 22889934 DOI: 10.1016/J.Dnarep.2012.07.001  0.45
2011 Bernstein KA, Reid RJ, Sunjevaric I, Demuth K, Burgess RC, Rothstein R. The Shu complex, which contains Rad51 paralogues, promotes DNA repair through inhibition of the Srs2 anti-recombinase. Molecular Biology of the Cell. 22: 1599-607. PMID 21372173 DOI: 10.1091/Mbc.E10-08-0691  0.43
2011 Robert T, Vanoli F, Chiolo I, Shubassi G, Bernstein KA, Rothstein R, Botrugno OA, Parazzoli D, Oldani A, Minucci S, Foiani M. HDACs link the DNA damage response, processing of double-strand breaks and autophagy. Nature. 471: 74-9. PMID 21368826 DOI: 10.1038/Nature09803  0.447
2010 Bernstein KA, Gangloff S, Rothstein R. The RecQ DNA helicases in DNA repair. Annual Review of Genetics. 44: 393-417. PMID 21047263 DOI: 10.1146/Annurev-Genet-102209-163602  0.438
2009 Bernstein KA, Rothstein R. At loose ends: resecting a double-strand break. Cell. 137: 807-10. PMID 19490890 DOI: 10.1016/J.Cell.2009.05.007  0.407
2009 Bernstein KA, Shor E, Sunjevaric I, Fumasoni M, Burgess RC, Foiani M, Branzei D, Rothstein R. Sgs1 function in the repair of DNA replication intermediates is separable from its role in homologous recombinational repair. The Embo Journal. 28: 915-25. PMID 19214189 DOI: 10.1038/Emboj.2009.28  0.461
2007 Bernstein KA, Bleichert F, Bean JM, Cross FR, Baserga SJ. Ribosome biogenesis is sensed at the Start cell cycle checkpoint. Molecular Biology of the Cell. 18: 953-64. PMID 17192414 DOI: 10.1091/Mbc.E06-06-0512  0.691
2006 Bernstein KA, Granneman S, Lee AV, Manickam S, Baserga SJ. Comprehensive mutational analysis of yeast DEXD/H box RNA helicases involved in large ribosomal subunit biogenesis. Molecular and Cellular Biology. 26: 1195-208. PMID 16449635 DOI: 10.1128/Mcb.26.4.1195-1208.2006  0.649
2006 Granneman S, Bernstein KA, Bleichert F, Baserga SJ. Comprehensive mutational analysis of yeast DEXD/H box RNA helicases required for small ribosomal subunit synthesis. Molecular and Cellular Biology. 26: 1183-94. PMID 16449634 DOI: 10.1128/Mcb.26.4.1183-1194.2006  0.698
2004 Bernstein KA, Gallagher JE, Mitchell BM, Granneman S, Baserga SJ. The small-subunit processome is a ribosome assembly intermediate. Eukaryotic Cell. 3: 1619-26. PMID 15590835 DOI: 10.1128/Ec.3.6.1619-1626.2004  0.676
2004 Bernstein KA, Baserga SJ. The small subunit processome is required for cell cycle progression at G1. Molecular Biology of the Cell. 15: 5038-46. PMID 15356263 DOI: 10.1091/Mbc.E04-06-0515  0.648
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