Shuo-Chien Ling, Ph.D. - Publications

Affiliations: 
2005 University of Illinois, Urbana-Champaign, Urbana-Champaign, IL 
Area:
Cellular Memory Mechanisms, Developmental Psychobiology, Fragile X syndrome

18/127 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2018 Lu W, Lakonishok M, Serpinskaya AS, Kirchenbüechler D, Ling SC, Gelfand VI. Ooplasmic flow cooperates with transport and anchorage in oocyte posterior determination. The Journal of Cell Biology. PMID 30037924 DOI: 10.1083/Jcb.201709174  0.68
2016 Tio M, Wen R, Lim YL, Wang H, Ling SC, Zhao Y, Tan EK. FUS-linked essential tremor associated with motor dysfunction in Drosophila. Human Genetics. PMID 27395408 DOI: 10.1007/s00439-016-1709-z  0.68
2016 Seredenina T, Nayernia Z, Sorce S, Maghzal GJ, Filippova A, Ling SC, Basset O, Plastre O, Daali Y, Rushing EJ, Giordana MT, Cleveland DW, Aguzzi A, Stocker R, Krause KH, et al. Evaluation of NADPH oxidases as drug targets in a mouse model of familial amyotrophic lateral sclerosis. Free Radical Biology & Medicine. PMID 27212019 DOI: 10.1016/J.Freeradbiomed.2016.05.016  0.68
2016 Jiang J, Zhu Q, Gendron TF, Saberi S, McAlonis-Downes M, Seelman A, Stauffer JE, Jafar-Nejad P, Drenner K, Schulte D, Chun S, Sun S, Ling SC, Myers B, Engelhardt J, et al. Gain of Toxicity from ALS/FTD-Linked Repeat Expansions in C9ORF72 Is Alleviated by Antisense Oligonucleotides Targeting GGGGCC-Containing RNAs. Neuron. PMID 27112497 DOI: 10.1016/J.Neuron.2016.04.006  0.68
2015 Sun S, Sun Y, Ling SC, Ferraiuolo L, McAlonis-Downes M, Zou Y, Drenner K, Wang Y, Ditsworth D, Tokunaga S, Kopelevich A, Kaspar BK, Lagier-Tourenne C, Cleveland DW. Translational profiling identifies a cascade of damage initiated in motor neurons and spreading to glia in mutant SOD1-mediated ALS. Proceedings of the National Academy of Sciences of the United States of America. PMID 26621731 DOI: 10.1073/Pnas.1520639112  0.68
2014 Cortes CJ, Ling SC, Guo LT, Hung G, Tsunemi T, Ly L, Tokunaga S, Lopez E, Sopher BL, Bennett CF, Shelton GD, Cleveland DW, La Spada AR. Muscle expression of mutant androgen receptor accounts for systemic and motor neuron disease phenotypes in spinal and bulbar muscular atrophy. Neuron. 82: 295-307. PMID 24742458 DOI: 10.1016/J.Neuron.2014.03.001  0.68
2013 Lagier-Tourenne C, Baughn M, Rigo F, Sun S, Liu P, Li HR, Jiang J, Watt AT, Chun S, Katz M, Qiu J, Sun Y, Ling SC, Zhu Q, Polymenidou M, et al. Targeted degradation of sense and antisense C9orf72 RNA foci as therapy for ALS and frontotemporal degeneration. Proceedings of the National Academy of Sciences of the United States of America. 110: E4530-9. PMID 24170860 DOI: 10.1073/Pnas.1318835110  0.68
2013 Ling SC, Polymenidou M, Cleveland DW. Converging mechanisms in ALS and FTD: disrupted RNA and protein homeostasis. Neuron. 79: 416-38. PMID 23931993 DOI: 10.1016/J.Neuron.2013.07.033  0.68
2013 Shelkovnikova TA, Peters OM, Deykin AV, Connor-Robson N, Robinson H, Ustyugov AA, Bachurin SO, Ermolkevich TG, Goldman IL, Sadchikova ER, Kovrazhkina EA, Skvortsova VI, Ling SC, Da Cruz S, Parone PA, et al. Fused in sarcoma (FUS) protein lacking nuclear localization signal (NLS) and major RNA binding motifs triggers proteinopathy and severe motor phenotype in transgenic mice. The Journal of Biological Chemistry. 288: 25266-74. PMID 23867462 DOI: 10.1074/Jbc.M113.492017  0.68
2013 Arnold ES, Ling SC, Huelga SC, Lagier-Tourenne C, Polymenidou M, Ditsworth D, Kordasiewicz HB, McAlonis-Downes M, Platoshyn O, Parone PA, Da Cruz S, Clutario KM, Swing D, Tessarollo L, Marsala M, et al. ALS-linked TDP-43 mutations produce aberrant RNA splicing and adult-onset motor neuron disease without aggregation or loss of nuclear TDP-43. Proceedings of the National Academy of Sciences of the United States of America. 110: E736-45. PMID 23382207 DOI: 10.1073/Pnas.1222809110  0.68
2012 Lagier-Tourenne C, Polymenidou M, Hutt KR, Vu AQ, Baughn M, Huelga SC, Clutario KM, Ling SC, Liang TY, Mazur C, Wancewicz E, Kim AS, Watt A, Freier S, Hicks GG, et al. Divergent roles of ALS-linked proteins FUS/TLS and TDP-43 intersect in processing long pre-mRNAs. Nature Neuroscience. 15: 1488-97. PMID 23023293 DOI: 10.1038/Nn.3230  0.68
2011 Polymenidou M, Lagier-Tourenne C, Hutt KR, Huelga SC, Moran J, Liang TY, Ling SC, Sun E, Wancewicz E, Mazur C, Kordasiewicz H, Sedaghat Y, Donohue JP, Shiue L, Bennett CF, et al. Long pre-mRNA depletion and RNA missplicing contribute to neuronal vulnerability from loss of TDP-43. Nature Neuroscience. 14: 459-68. PMID 21358643 DOI: 10.1038/Nn.2779  0.68
2010 Ling SC, Albuquerque CP, Han JS, Lagier-Tourenne C, Tokunaga S, Zhou H, Cleveland DW. ALS-associated mutations in TDP-43 increase its stability and promote TDP-43 complexes with FUS/TLS. Proceedings of the National Academy of Sciences of the United States of America. 107: 13318-23. PMID 20624952 DOI: 10.1073/Pnas.1008227107  0.68
2007 Kim H, Ling SC, Rogers GC, Kural C, Selvin PR, Rogers SL, Gelfand VI. Microtubule binding by dynactin is required for microtubule organization but not cargo transport. The Journal of Cell Biology. 176: 641-51. PMID 17325206 DOI: 10.1083/Jcb.200608128  0.68
2005 Angenstein F, Evans AM, Ling SC, Settlage RE, Ficarro S, Carrero-Martinez FA, Shabanowitz J, Hunt DF, Greenough WT. Proteomic characterization of messenger ribonucleoprotein complexes bound to nontranslated or translated poly(A) mRNAs in the rat cerebral cortex. The Journal of Biological Chemistry. 280: 6496-503. PMID 15596439 DOI: 10.1074/Jbc.M412742200  0.68
2004 Ling SC, Fahrner PS, Greenough WT, Gelfand VI. Transport of Drosophila fragile X mental retardation protein-containing ribonucleoprotein granules by kinesin-1 and cytoplasmic dynein. Proceedings of the National Academy of Sciences of the United States of America. 101: 17428-33. PMID 15583137 DOI: 10.1073/pnas.0408114101  0.68
2002 Angenstein F, Evans AM, Settlage RE, Moran ST, Ling SC, Klintsova AY, Shabanowitz J, Hunt DF, Greenough WT. A receptor for activated C kinase is part of messenger ribonucleoprotein complexes associated with polyA-mRNAs in neurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 22: 8827-37. PMID 12388589 DOI: 10.1523/Jneurosci.22-20-08827.2002  0.68
1998 Lai SL, Ling SC, Kuo LH, Shu YC, Chow WY, Chang YC. Characterization of granular particles isolated from postsynaptic densities. Journal of Neurochemistry. 71: 1694-701. PMID 9751204 DOI: 10.1046/J.1471-4159.1998.71041694.X  0.68
Low-probability matches
2015 Jiménez-Rivera C, Ling SC, Ahmed N, Yap J, Aglipay M, Barrowman N, Graitson S, Critch J, Rashid M, Ng VL, Roberts EA, Brill H, Dowhaniuk JK, Bruce G, Bax K, et al. Incidence and Characteristics of Autoimmune Hepatitis. Pediatrics. PMID 26482664 DOI: 10.1542/Peds.2015-0578  0.04
2015 Valentino PL, Feldman BM, Walters TD, Griffiths AM, Ling SC, Pullenayegum EM, Kamath BM. Abnormal Liver Biochemistry Is Common in Pediatric Inflammatory Bowel Disease: Prevalence and Associations. Inflammatory Bowel Diseases. PMID 26273817 DOI: 10.1097/MIB.0000000000000558  0.04
2015 Jonas MM, Chang MH, Sokal E, Schwarz KB, Kelly D, Mo Kim K, Ling SC, Rosenthal P, Oraseanu D, Reynolds L, Thiry A, Ackerman P. Randomized Controlled Trial of Entecavir Versus Placebo in Children with HBeAg-positive Chronic Hepatitis B. Hepatology (Baltimore, Md.). PMID 26223345 DOI: 10.1002/Hep.28015  0.04
2015 Mitchell JC, Constable R, So E, Vance C, Scotter E, Glover L, Hortobagyi T, Arnold ES, Ling SC, McAlonis M, Da Cruz S, Polymenidou M, Tessarolo L, Cleveland DW, Shaw CE. Wild type human TDP-43 potentiates ALS-linked mutant TDP-43 driven progressive motor and cortical neuron degeneration with pathological features of ALS. Acta Neuropathologica Communications. 3: 36. PMID 26108367 DOI: 10.1186/S40478-015-0212-4  0.04
2015 Laurence JM, Sapisochin G, DeAngelis M, Seal JB, Miserachs MM, Marquez M, Zair M, Fecteau A, Jones N, Hrycko A, Avitzur Y, Ling SC, Ng V, Cattral M, Grant D, et al. Biliary complications in pediatric liver transplantation: Incidence and management over a decade. Liver Transplantation : Official Publication of the American Association For the Study of Liver Diseases and the International Liver Transplantation Society. 21: 1082-90. PMID 25991054 DOI: 10.1002/lt.24180  0.04
2015 Jancelewicz T, Barmherzig R, Chung CT, Ling SC, Kamath BM, Ng VL, Amaral J, O'Connor C, Fecteau A, Langer JC. A screening algorithm for the efficient exclusion of biliary atresia in infants with cholestatic jaundice. Journal of Pediatric Surgery. 50: 363-70. PMID 25746690 DOI: 10.1016/j.jpedsurg.2014.08.014  0.04
2015 Sun S, Ling SC, Qiu J, Albuquerque CP, Zhou Y, Tokunaga S, Li H, Qiu H, Bui A, Yeo GW, Huang EJ, Eggan K, Zhou H, Fu XD, Lagier-Tourenne C, et al. ALS-causative mutations in FUS/TLS confer gain and loss of function by altered association with SMN and U1-snRNP. Nature Communications. 6: 6171. PMID 25625564 DOI: 10.1038/Ncomms7171  0.04
2015 Rajpurkar M, Sharathkumar A, Williams S, Lau K, Ling SC, Chan AK. Recommendations for the assessment of non-extremity venous thromboembolism outcomes: communication from the SSC of the ISTH. Journal of Thrombosis and Haemostasis : Jth. 13: 477-80. PMID 25472633 DOI: 10.1111/jth.12809  0.04
2014 Propst EJ, Ling SC, Daneman A, Langer JC. Endoscopic clip for closure of persistent tracheoesophageal fistula in an infant. The Laryngoscope. 124: 2182-5. PMID 25295352 DOI: 10.1002/lary.24650  0.04
2014 Walsh CM, Ling SC, Walters TD, Mamula P, Lightdale JR, Carnahan H. Development of the gastrointestinal endoscopy competency assessment tool for pediatric colonoscopy (GiECAT KIDS). Journal of Pediatric Gastroenterology and Nutrition. 59: 480-6. PMID 24590220 DOI: 10.1097/Mpg.0000000000000358  0.04
2014 Diamond IR, Grant RC, Feldman BM, Pencharz PB, Ling SC, Moore AM, Wales PW. Defining consensus: a systematic review recommends methodologic criteria for reporting of Delphi studies. Journal of Clinical Epidemiology. 67: 401-9. PMID 24581294 DOI: 10.1016/J.Jclinepi.2013.12.002  0.04
2014 Zhu L, Lee B, Zhao F, Zhou X, Chin V, Ling SC, Chen Y. Modulation of airway epithelial antiviral immunity by fungal exposure. American Journal of Respiratory Cell and Molecular Biology. 50: 1136-43. PMID 24428709 DOI: 10.1165/Rcmb.2013-0357Oc  0.04
2014 Walsh CM, Ling SC, Khanna N, Cooper MA, Grover SC, May G, Walters TD, Rabeneck L, Reznick R, Carnahan H. Gastrointestinal Endoscopy Competency Assessment Tool: development of a procedure-specific assessment tool for colonoscopy. Gastrointestinal Endoscopy. 79: 798-807.e5. PMID 24321390 DOI: 10.1016/J.Gie.2013.10.035  0.04
2014 Diamond IR, Grant RC, Feldman BM, Tomlinson GA, Pencharz PB, Ling SC, Moore AM, Wales PW. Expert beliefs regarding novel lipid-based approaches to pediatric intestinal failure-associated liver disease. Jpen. Journal of Parenteral and Enteral Nutrition. 38: 702-10. PMID 23917524 DOI: 10.1177/0148607113494213  0.04
2014 Valentino PL, Ling SC, Ng VL, John P, Bonasoni P, Castro DA, Taylor G, Chavhan GB, Kamath BM. The role of diagnostic imaging and liver biopsy in the diagnosis of focal nodular hyperplasia in children. Liver International : Official Journal of the International Association For the Study of the Liver. 34: 227-34. PMID 23829376 DOI: 10.1111/liv.12241  0.04
2013 Ling SC. 50 Years ago in The Journal of Pediatrics: jaundice associated with severe bacterial infection in young infants. The Journal of Pediatrics. 163: 242. PMID 23796340 DOI: 10.1016/j.jpeds.2013.01.068  0.04
2013 Popalis C, Yeung LT, Ling SC, Ng V, Roberts EA. Chronic hepatitis B virus (HBV) infection in children: 25 years' experience. Journal of Viral Hepatitis. 20: e20-6. PMID 23490385 DOI: 10.1111/jvh.12019  0.04
2012 Ling SC. Advances in the evaluation and management of children with portal hypertension. Seminars in Liver Disease. 32: 288-97. PMID 23397529 DOI: 10.1055/s-0032-1329897  0.04
2012 Diamond IR, Pencharz PB, Feldman BM, Ling SC, Moore AM, Wales PW. Novel lipid-based approaches to pediatric intestinal failure-associated liver disease. Archives of Pediatrics & Adolescent Medicine. 166: 473-8. PMID 22566549 DOI: 10.1001/Archpediatrics.2011.1896  0.04
2012 Shneider BL, Bosch J, de Franchis R, Emre SH, Groszmann RJ, Ling SC, Lorenz JM, Squires RH, Superina RA, Thompson AE, Mazariegos GV. Portal hypertension in children: expert pediatric opinion on the report of the Baveno v Consensus Workshop on Methodology of Diagnosis and Therapy in Portal Hypertension. Pediatric Transplantation. 16: 426-37. PMID 22409296 DOI: 10.1111/j.1399-3046.2012.01652.x  0.04
2012 Zolkipli Z, Sherlock M, Biggar WD, Taylor G, Hutchison JS, Peliowski A, Alman BA, Ling SC, Tein I. Abnormal fatty acid metabolism in spinal muscular atrophy may predispose to perioperative risks. European Journal of Paediatric Neurology : Ejpn : Official Journal of the European Paediatric Neurology Society. 16: 549-53. PMID 22264649 DOI: 10.1016/J.Ejpn.2012.01.004  0.04
2011 Diamond IR, de Silva NT, Tomlinson GA, Pencharz PB, Feldman BM, Moore AM, Ling SC, Wales PW. The role of parenteral lipids in the development of advanced intestinal failure-associated liver disease in infants: a multiple-variable analysis. Jpen. Journal of Parenteral and Enteral Nutrition. 35: 596-602. PMID 21825088 DOI: 10.1177/0148607111413598  0.04
2011 Traubici J, Somers GR, Ling SC, Pearl RJ, Nathan PC. Pleuropulmonary blastoma in a child with autosomal-recessive polycystic kidney disease. Pediatric Radiology. 41: 1465-8. PMID 21720858 DOI: 10.1007/s00247-011-2026-2  0.04
2011 Gana JC, Valentino PL, Morinville V, O'Connor C, Ling SC. Variation in care for children with esophageal varices: a study of physicians', patients', and families' approaches and attitudes. Journal of Pediatric Gastroenterology and Nutrition. 52: 751-5. PMID 21593647 DOI: 10.1097/MPG.0b013e318213be81  0.04
2011 Fang M, Huang JY, Wang J, Ling SC, Rudd JA, Hu ZY, Xu LH, Yuan ZG, Han S. Anti-neuroinflammatory and neurotrophic effects of combined therapy with annexin II and Reg-2 on injured spinal cord. Neuro-Signals. 19: 16-43. PMID 21430360 DOI: 10.1159/000324272  0.04
2011 Revel-Vilk S, Komvilaisak P, Blanchette V, Stain AM, Floros G, Cochrane A, Blanchette C, Hang M, Roberts EA, Ling SC. The changing face of hepatitis in boys with haemophilia associated with increased prevalence of obesity. Haemophilia : the Official Journal of the World Federation of Hemophilia. 17: 689-94. PMID 21418443 DOI: 10.1111/j.1365-2516.2010.02477.x  0.04
2011 Carter-Kent C, Brunt EM, Yerian LM, Alkhouri N, Angulo P, Kohli R, Ling SC, Xanthakos SA, Whitington PF, Charatcharoenwitthaya P, Yap J, Lopez R, McCullough AJ, Feldstein AE. Relations of steatosis type, grade, and zonality to histological features in pediatric nonalcoholic fatty liver disease. Journal of Pediatric Gastroenterology and Nutrition. 52: 190-7. PMID 21240012 DOI: 10.1097/Mpg.0B013E3181Fb47D3  0.04
2011 Fang M, Wang J, Huang JY, Ling SC, Rudd JA, Hu ZY, Yew DT, Han S. The neuroprotective effects of Reg-2 following spinal cord transection injury. Anatomical Record (Hoboken, N.J. : 2007). 294: 24-45. PMID 21157914 DOI: 10.1002/ar.21281  0.04
2021 Chang KJ, Agrawal I, Vainshtein A, Ho WY, Xin W, Tucker-Kellogg G, Susuki K, Peles E, Ling SC, Chan JR. TDP-43 maximizes nerve conduction velocity by repressing a cryptic exon for paranodal junction assembly in Schwann cells. Elife. 10. PMID 33689679 DOI: 10.7554/eLife.64456  0.01
2021 Klionsky DJ, Abdel-Aziz AK, Abdelfatah S, Abdellatif M, Abdoli A, Abel S, Abeliovich H, Abildgaard MH, Abudu YP, Acevedo-Arozena A, Adamopoulos IE, Adeli K, Adolph TE, Adornetto A, Aflaki E, ... ... Ling SC, et al. Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition). Autophagy. 1-382. PMID 33634751 DOI: 10.1080/15548627.2020.1797280  0.01
2021 Ho WY, Agrawal I, Tyan SH, Sanford E, Chang WT, Lim K, Ong J, Tan BSY, Moe AAK, Yu R, Wong P, Tucker-Kellogg G, Koo E, Chuang KH, Ling SC. Dysfunction in nonsense-mediated decay, protein homeostasis, mitochondrial function, and brain connectivity in ALS-FUS mice with cognitive deficits. Acta Neuropathologica Communications. 9: 9. PMID 33407930 DOI: 10.1186/s40478-020-01111-4  0.01
2020 Peng AYT, Agrawal I, Ho WY, Yen YC, Pinter AJ, Liu J, Phua QXC, Koh KB, Chang JC, Sanford E, Man JHK, Wong P, Gutmann DH, Tucker-Kellogg G, Ling SC. Loss of TDP-43 in astrocytes leads to motor deficits by triggering A1-like reactive phenotype and triglial dysfunction. Proceedings of the National Academy of Sciences of the United States of America. PMID 33127758 DOI: 10.1073/pnas.2007806117  0.01
2020 Ho WY, Navakkode S, Liu F, Soong TW, Ling SC. Deregulated expression of a longevity gene, Klotho, in the C9orf72 deletion mice with impaired synaptic plasticity and adult hippocampal neurogenesis. Acta Neuropathologica Communications. 8: 155. PMID 32887666 DOI: 10.1186/s40478-020-01030-4  0.01
2020 Wong P, Ho WY, Yen YC, Sanford E, Ling SC. The vulnerability of motor and frontal cortex-dependent behaviors in mice expressing ALS-linked mutation in TDP-43. Neurobiology of Aging. 92: 43-60. PMID 32422502 DOI: 10.1016/J.Neurobiolaging.2020.03.019  0.01
2020 López-Erauskin J, Tadokoro T, Baughn MW, Myers B, McAlonis-Downes M, Chillon-Marinas C, Asiaban JN, Artates J, Bui AT, Vetto AP, Lee SK, Le AV, Sun Y, Jambeau M, Boubaker J, ... ... Ling SC, et al. ALS/FTD-Linked Mutation in FUS Suppresses Intra-axonal Protein Synthesis and Drives Disease Without Nuclear Loss-of-Function of FUS. Neuron. 106: 354. PMID 32325059 DOI: 10.1016/j.neuron.2020.04.006  0.04
2019 Ho WY, Chang JC, Tyan SH, Yen YC, Lim K, Tan BSY, Ong J, Tucker-Kellogg G, Wong P, Koo E, Ling SC. FUS-mediated dysregulation of Sema5a, an autism-related gene, in FUS mice with hippocampus-dependent cognitive deficits. Human Molecular Genetics. PMID 31509188 DOI: 10.1093/Hmg/Ddz217  0.01
2019 Cali CP, Patino M, Tai YK, Ho WY, McLean CA, Morris CM, Seeley WW, Miller BL, Gaig C, Vonsattel JPG, White CL, Roeber S, Kretzschmar H, Troncoso JC, Troakes C, ... ... Ling SC, et al. C9orf72 intermediate repeats are associated with corticobasal degeneration, increased C9orf72 expression and disruption of autophagy. Acta Neuropathologica. PMID 31327044 DOI: 10.1007/S00401-019-02045-5  0.01
2019 Ho WY, Ling SC. Elevated FUS levels by overriding its autoregulation produce gain-of-toxicity properties that disrupt protein and RNA homeostasis. Autophagy. 1-3. PMID 31230528 DOI: 10.1080/15548627.2019.1633162  0.01
2019 Ling SC, Dastidar SG, Tokunaga S, Ho WY, Lim K, Ilieva H, Parone PA, Tyan SH, Tse TM, Chang JC, Platoshyn O, Bui NB, Bui A, Vetto A, Sun S, et al. Overriding FUS autoregulation in mice triggers gain-of-toxic dysfunctions in RNA metabolism and autophagy-lysosome axis. Elife. 8. PMID 30747709 DOI: 10.7554/Elife.40811  0.04
2019 Ho WY, Tai YK, Chang JC, Liang J, Tyan SH, Chen S, Guan JL, Zhou H, Shen HM, Koo E, Ling SC. The ALS-FTD-linked gene product, C9orf72, regulates neuronal morphogenesis via autophagy. Autophagy. PMID 30669939 DOI: 10.1080/15548627.2019.1569441  0.04
2019 Ling S, Dastidar SG, Tokunaga S, Ho WY, Lim K, Ilieva H, Parone PA, Tyan S, Tse TM, Chang J, Platoshyn O, Bui NB, Bui A, Vetto A, Sun S, et al. Author response: Overriding FUS autoregulation in mice triggers gain-of-toxic dysfunctions in RNA metabolism and autophagy-lysosome axis Elife. DOI: 10.7554/Elife.40811.039  0.04
2018 Wang J, Ho WY, Lim K, Feng J, Tucker-Kellogg G, Nave KA, Ling SC. Cell-autonomous requirement of TDP-43, an ALS/FTD signature protein, for oligodendrocyte survival and myelination. Proceedings of the National Academy of Sciences of the United States of America. PMID 30373824 DOI: 10.1073/Pnas.1809821115  0.01
2018 López-Erauskin J, Tadokoro T, Baughn MW, Myers B, McAlonis-Downes M, Chillon-Marinas C, Asiaban JN, Artates J, Bui AT, Vetto AP, Lee SK, Le AV, Sun Y, Jambeau M, Boubaker J, ... ... Ling SC, et al. ALS/FTD-Linked Mutation in FUS Suppresses Intra-axonal Protein Synthesis and Drives Disease Without Nuclear Loss-of-Function of FUS. Neuron. PMID 30344044 DOI: 10.1016/J.Neuron.2018.09.044  0.04
2018 Ling SC. Synaptic Paths to Neurodegeneration: The Emerging Role of TDP-43 and FUS in Synaptic Functions. Neural Plasticity. 2018: 8413496. PMID 29755516 DOI: 10.1155/2018/8413496  0.01
2018 Bennett CL, Dastidar SG, Ling SC, Malik B, Ashe T, Wadhwa M, Miller DB, Lee C, Mitchell MB, van Es MA, Grunseich C, Chen Y, Sopher BL, Greensmith L, Cleveland DW, et al. Senataxin mutations elicit motor neuron degeneration phenotypes and yield TDP-43 mislocalization in ALS4 mice and human patients. Acta Neuropathologica. PMID 29725819 DOI: 10.1007/S00401-018-1852-9  0.04
2017 Ditsworth D, Maldonado M, McAlonis-Downes M, Sun S, Seelman A, Drenner K, Arnold E, Ling SC, Pizzo D, Ravits J, Cleveland DW, Da Cruz S. Mutant TDP-43 within motor neurons drives disease onset but not progression in amyotrophic lateral sclerosis. Acta Neuropathologica. PMID 28357566 DOI: 10.1007/S00401-017-1698-6  0.04
2015 Nikesitch N, Ling SC. Molecular mechanisms in multiple myeloma drug resistance. Journal of Clinical Pathology. PMID 26598624 DOI: 10.1136/jclinpath-2015-203414  0.01
2015 Schwarz KB, Cloonan YK, Ling SC, Murray KF, Rodriguez-Baez N, Schwarzenberg SJ, Teckman J, Ganova-Raeva L, Rosenthal P. Children with Chronic Hepatitis B in the United States and Canada. The Journal of Pediatrics. PMID 26364985 DOI: 10.1016/J.Jpeds.2015.08.021  0.01
2015 Shneider BL, de Ville de Goyet J, Leung D, Srivastava A, Ling SC, Duché M, McKiernan P, Superina R, Squires RH, Bosch J, Groszmann R, Sarin S, de Franchis R, Mazariegos G. Primary Prophylaxis of Variceal Bleeding in Children and the Role of MesoRex Bypass-Summary of the Baveno VI Pediatric Satellite Symposium. Hepatology (Baltimore, Md.). PMID 26358549 DOI: 10.1002/hep.28153  0.01
2015 Carpenter A, Ng VL, Chapman K, Ling SC, Mouzaki M. Predictive Equations Are Inaccurate in the Estimation of the Resting Energy Expenditure of Children With End-Stage Liver Disease. Jpen. Journal of Parenteral and Enteral Nutrition. PMID 26205222 DOI: 10.1177/0148607115597666  0.01
2015 Walsh CM, Ling SC, Khanna N, Grover SC, Yu JJ, Cooper MA, Yong E, Nguyen GC, May G, Walters TD, Reznick R, Rabeneck L, Carnahan H. Gastrointestinal Endoscopy Competency Assessment Tool: reliability and validity evidence. Gastrointestinal Endoscopy. 81: 1417-1424.e2. PMID 25753836 DOI: 10.1016/J.Gie.2014.11.030  0.01
2015 Hatlani MA, Kortan P, May G, Ling SC, Walters T, Avitzur Y. Wire-guided cannulation versus contrast-guided cannulation in pediatric endoscopic retrograde cholangiopancreatography. Saudi Journal of Gastroenterology : Official Journal of the Saudi Gastroenterology Association. 21: 25-9. PMID 25672235 DOI: 10.4103/1319-3767.151219  0.01
2015 Shlien A, Campbell BB, de Borja R, Alexandrov LB, Merico D, Wedge D, Van Loo P, Tarpey PS, Coupland P, Behjati S, Pollett A, Lipman T, Heidari A, Deshmukh S, Avitzur N, ... Ling SC, et al. Combined hereditary and somatic mutations of replication error repair genes result in rapid onset of ultra-hypermutated cancers. Nature Genetics. 47: 257-62. PMID 25642631 DOI: 10.1038/Ng.3202  0.01
2015 Walsh CM, Ling SC, Mamula P, Lightdale JR, Walters TD, Yu JJ, Carnahan H. The gastrointestinal endoscopy competency assessment tool for pediatric colonoscopy. Journal of Pediatric Gastroenterology and Nutrition. 60: 474-80. PMID 25564819 DOI: 10.1097/Mpg.0000000000000686  0.01
2015 Hayes W, Tschumi S, Ling SC, Feber J, Kirschfink M, Licht C. Eculizumab hepatotoxicity in pediatric aHUS. Pediatric Nephrology (Berlin, Germany). 30: 775-81. PMID 25416628 DOI: 10.1007/s00467-014-2990-5  0.01
2015 Liu AP, Shing MM, Yuen HL, Li CH, Ling SC, Luk CW, Ha SY, Li CK, Chan GC. Central nervous system tumors in chinese children under the age of 3: a population study. Journal of Pediatric Hematology/Oncology. 37: 94-103. PMID 24608077 DOI: 10.1097/MPH.0000000000000128  0.01
2014 Colli A, Gana JC, Turner D, Yap J, Adams-Webber T, Ling SC, Casazza G. Capsule endoscopy for the diagnosis of oesophageal varices in people with chronic liver disease or portal vein thrombosis. The Cochrane Database of Systematic Reviews. 10: CD008760. PMID 25271409 DOI: 10.1002/14651858.CD008760.pub2  0.01
2014 Chan CC, To KF, Yuen HL, Shing Chiang AK, Ling SC, Li CH, Cheuk DK, Li CK, Shing MM. A 20-year prospective study of Wilms tumor and other kidney tumors: a report from Hong Kong pediatric hematology and oncology study group. Journal of Pediatric Hematology/Oncology. 36: 445-50. PMID 25050908 DOI: 10.1097/MPH.0000000000000018  0.01
2014 Mouzaki M, Ng V, Kamath BM, Selzner N, Pencharz P, Ling SC. Enteral energy and macronutrients in end-stage liver disease. Jpen. Journal of Parenteral and Enteral Nutrition. 38: 673-81. PMID 24531707 DOI: 10.1177/0148607114522488  0.01
2014 Ling SC, Avitzur Y. Predicting outcomes for children awaiting liver transplantation: is serum sodium the answer? Hepatology (Baltimore, Md.). 59: 1678-80. PMID 24375691 DOI: 10.1002/hep.26985  0.01
2014 Liu AP, Shing MM, Yuen HL, Li CH, Ling SC, Luk CW, Ha SY, Li CK, Kwong DL, Chan GC. Timing of adjuvant radiotherapy and treatment outcome in childhood ependymoma. Pediatric Blood & Cancer. 61: 606-11. PMID 24167035 DOI: 10.1002/pbc.24820  0.01
2013 Cheng SH, Lau KM, Li CK, Chan NP, Ip RK, Cheng CK, Lee V, Shing MM, Leung AW, Ha SY, Cheuk DK, Lee AC, Li CH, Luk CW, Ling SC, et al. Minimal residual disease-based risk stratification in Chinese childhood acute lymphoblastic leukemia by flow cytometry and plasma DNA quantitative polymerase chain reaction. Plos One. 8: e69467. PMID 23936021 DOI: 10.1371/Journal.Pone.0069467  0.01
2013 Woolfson J, John P, Kamath B, Ng VL, Ling SC. Measurement of hepatic venous pressure gradient is feasible and safe in children. Journal of Pediatric Gastroenterology and Nutrition. 57: 634-7. PMID 23799453 DOI: 10.1097/MPG.0b013e3182a0e114  0.01
2013 Tayler R, Barclay AR, Rogers P, Mcintyre K, Russell RK, Devadason D, Bisset WM, Ling SC, McGrogan P. Scottish outcomes for extra hepatic biliary atresia post-rationalisation of services. Archives of Disease in Childhood. 98: 381-3. PMID 23429893 DOI: 10.1136/archdischild-2011-301608  0.01
2013 Sokollik C, Bandsma RH, Gana JC, van den Heuvel M, Ling SC. Congenital portosystemic shunt: characterization of a multisystem disease. Journal of Pediatric Gastroenterology and Nutrition. 56: 675-81. PMID 23412540 DOI: 10.1097/MPG.0b013e31828b3750  0.01
2012 Brode SK, Ling SC, Chapman KR. Alpha-1 antitrypsin deficiency: a commonly overlooked cause of lung disease. Cmaj : Canadian Medical Association Journal = Journal De L'Association Medicale Canadienne. 184: 1365-71. PMID 22761482 DOI: 10.1503/cmaj.111749  0.01
2012 Walsh CM, Sherlock ME, Ling SC, Carnahan H. Virtual reality simulation training for health professions trainees in gastrointestinal endoscopy. The Cochrane Database of Systematic Reviews. 6: CD008237. PMID 22696375 DOI: 10.1002/14651858.Cd008237.Pub2  0.01
2012 Leung AW, Vincent L, Chiang AK, Lee AC, Cheng FW, Cheuk DK, Luk CW, Ling SC, Li CK. Prognosis and outcome of relapsed acute lymphoblastic leukemia: a Hong Kong Pediatric Hematology and Oncology Study Group report. Pediatric Blood & Cancer. 59: 454-60. PMID 22610685 DOI: 10.1002/pbc.24162  0.01
2012 Han F, Yang J, Yu WF, Yin YF, Wu SX, Ling SC. [GAD67-GFP expression and co-localization with bNOS in main olfactory bulb of GAD67-GFP knock-in mouse]. Zhejiang Da Xue Xue Bao. Yi Xue Ban = Journal of Zhejiang University. Medical Sciences. 41: 159-65, 170. PMID 22499512  0.01
2012 Ling SC, Lau EK, Al-Shabeeb A, Nikolic A, Catalano A, Iland H, Horvath N, Ho PJ, Harrison S, Fleming S, Joshua DE, Allen JD. Response of myeloma to the proteasome inhibitor bortezomib is correlated with the unfolded protein response regulator XBP-1. Haematologica. 97: 64-72. PMID 21993678 DOI: 10.3324/haematol.2011.043331  0.01
2011 Walsh CM, Rose DN, Dubrowski A, Ling SC, Grierson LE, Backstein D, Carnahan H. Learning in the simulated setting: a comparison of expert-, peer-, and computer-assisted learning. Academic Medicine : Journal of the Association of American Medical Colleges. 86: S12-6. PMID 21955760 DOI: 10.1097/Acm.0B013E31822A72C7  0.01
2011 Gana JC, Turner D, Mieli-Vergani G, Davenport M, Miloh T, Avitzur Y, Yap J, Morinville V, Brill H, Ling SC. A clinical prediction rule and platelet count predict esophageal varices in children. Gastroenterology. 141: 2009-16. PMID 21925123 DOI: 10.1053/j.gastro.2011.08.049  0.01
2011 Ling SC, Tsuge T, Sudesh K. Biosynthesis of novel polyhydroxyalkanoate containing 3-hydroxy-4-methylvalerate by Chromobacterium sp. USM2. Journal of Applied Microbiology. 111: 559-71. PMID 21689225 DOI: 10.1111/j.1365-2672.2011.05084.x  0.01
2011 So CC, Chan AY, Luo HY, Verhovsek M, Chui DH, Ling SC, Chan LC. Hb A2 Hong Kong - A novel δ-globin variant in a Chinese family masks the diagnosis of β-thalassemia trait. Hemoglobin. 35: 162-5. PMID 21417575 DOI: 10.3109/03630269.2011.557172  0.01
2011 Siu WK, Ma RC, Lam CW, Mak CM, Yuen YP, Lo FM, Chan KW, Lam SF, Ling SC, Tong SF, So WY, Chow CC, Tang MH, Tam WH, Chan AY. Molecular basis of von Hippel-Lindau syndrome in Chinese patients. Chinese Medical Journal. 124: 237-41. PMID 21362373 DOI: 10.3760/Cma.J.Issn.0366-6999.2011.02.016  0.01
2011 Wu ZM, Chen YF, Qiu PN, Ling SC. Correlation between the distribution of SP and CGRP immunopositive neurons in dorsal root ganglia and the afferent sensation of preputial frenulum. Anatomical Record (Hoboken, N.J. : 2007). 294: 479-86. PMID 21337713 DOI: 10.1002/ar.21327  0.01
2011 Ling SC, Walters T, McKiernan PJ, Schwarz KB, Garcia-Tsao G, Shneider BL. Primary prophylaxis of variceal hemorrhage in children with portal hypertension: a framework for future research. Journal of Pediatric Gastroenterology and Nutrition. 52: 254-61. PMID 21336158 DOI: 10.1097/MPG.0b013e318205993a  0.01
2011 Zhou SY, Xu SJ, Yan YG, Yu HM, Ling SC, Luo JH. Decreased purinergic inhibition of synaptic activity in a mouse model of Niemann-Pick disease type C. Hippocampus. 21: 212-9. PMID 20082288 DOI: 10.1002/Hipo.20741  0.01
2010 Rasalkar DD, Chu WC, Cheng FW, Hui SK, Ling SC, Li CK. A pictorial review of imaging of abdominal tumours in adolescence. Pediatric Radiology. 40: 1552-61; quiz 1589-9. PMID 20602098 DOI: 10.1007/s00247-010-1738-z  0.01
2010 Li YQ, Chen HH, Yin YF, Han F, Ye XS, Ling SC. [Formaldehyde inhalation may damage olfactory bulb and hippocampus in rats]. Zhejiang Da Xue Xue Bao. Yi Xue Ban = Journal of Zhejiang University. Medical Sciences. 39: 272-7. PMID 20544989  0.01
2010 Zhang XM, Shi PH, Cao SH, Yu HJ, Azad J, Ling SC. Expression changes of transforming growth factor-beta1 and thrombospondin-1 in cavernous tissues of diabetic rats. Urologia Internationalis. 84: 221-5. PMID 20215829 DOI: 10.1159/000277602  0.01
2010 Fang M, Huang JY, Ling SC, Rudd JA, Yew DT, Han S. Effects of Reg-2 on survival of spinal cord neurons in vitro. Anatomical Record (Hoboken, N.J. : 2007). 293: 464-76. PMID 20091885 DOI: 10.1002/ar.21087  0.04
2010 Gana JC, Turner D, Roberts EA, Ling SC. Derivation of a clinical prediction rule for the noninvasive diagnosis of varices in children. Journal of Pediatric Gastroenterology and Nutrition. 50: 188-93. PMID 19966576 DOI: 10.1097/MPG.0b013e3181b64437  0.04
2010 Ooi CY, Brandão LR, Zolpys L, De Angelis M, Drew W, Jones N, Ling SC, Fecteau A, Ng VL. Thrombotic events after pediatric liver transplantation. Pediatric Transplantation. 14: 476-82. PMID 19849808 DOI: 10.1111/j.1399-3046.2009.01252.x  0.01
2009 Benchimol EI, Walsh CM, Ling SC. Early diagnosis of neonatal cholestatic jaundice: test at 2 weeks. Canadian Family Physician MéDecin De Famille Canadien. 55: 1184-92. PMID 20008595  0.01
2009 Turner D, Benchimol EI, Dunn H, Griffiths AM, Frost K, Scaini V, Avolio J, Ling SC. Pico-Salax versus polyethylene glycol for bowel cleanout before colonoscopy in children: a randomized controlled trial. Endoscopy. 41: 1038-45. PMID 19967619 DOI: 10.1055/s-0029-1215333  0.01
2009 Walsh CM, Ling SC, Wang CS, Carnahan H. Concurrent versus terminal feedback: it may be better to wait. Academic Medicine : Journal of the Association of American Medical Colleges. 84: S54-7. PMID 19907387 DOI: 10.1097/Acm.0B013E3181B38Daf  0.01
2009 Bartlett JR, Friedman KJ, Ling SC, Pace RG, Bell SC, Bourke B, Castaldo G, Castellani C, Cipolli M, Colombo C, Colombo JL, Debray D, Fernandez A, Lacaille F, Macek M, et al. Genetic modifiers of liver disease in cystic fibrosis. Jama. 302: 1076-83. PMID 19738092 DOI: 10.1001/Jama.2009.1295  0.04
2009 Carter-Kent C, Yerian LM, Brunt EM, Angulo P, Kohli R, Ling SC, Xanthakos SA, Whitington PF, Charatcharoenwitthaya P, Yap J, Lopez R, McCullough AJ, Feldstein AE. Nonalcoholic steatohepatitis in children: a multicenter clinicopathological study. Hepatology (Baltimore, Md.). 50: 1113-20. PMID 19637190 DOI: 10.1002/Hep.23133  0.04
2009 Lee SY, Li CK, Ling SC, Shiu YK. Survival of homozygous alpha-thalassemia with aplasia/hypoplasia of phalanges and jejunal atresia. The Journal of Maternal-Fetal & Neonatal Medicine : the Official Journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians. 22: 711-3. PMID 19521930 DOI: 10.1080/14767050902994556  0.04
2009 Ling SC, Pfeiffer A, Avitzur Y, Fecteau A, Grant D, Ng VL. Long-term follow-up of portal hypertension after liver transplantation in children. Pediatric Transplantation. 13: 206-9. PMID 18564308 DOI: 10.1111/j.1399-3046.2008.00993.x  0.01
2008 Zhou J, Sun BQ, Gao RL, Zheng LH, Ling SC. [Cortical neuron apoptosis induced by beta-amyloid peptide and protective effect of panoxadiol in mice]. Zhejiang Da Xue Xue Bao. Yi Xue Ban = Journal of Zhejiang University. Medical Sciences. 37: 451-5. PMID 18925710  0.01
2008 Samonte VA, Sherman PM, Taylor GP, Carricato MN, Fecteau A, Ling SC, Ng VL. Scurvy diagnosed in a pediatric liver transplant patient awaiting combined kidney and liver retransplantation. Pediatric Transplantation. 12: 363-7. PMID 18331545 DOI: 10.1111/j.1399-3046.2007.00800.x  0.04
2008 Noli K, Solomon M, Golding F, Charron M, Ling SC. Prevalence of hepatopulmonary syndrome in children. Pediatrics. 121: e522-7. PMID 18310172 DOI: 10.1542/Peds.2007-1075  0.04
2008 El-Matary W, Roberts EA, Kim P, Temple M, Cutz E, Ling SC. Portal hypertensive biliopathy: a rare cause of childhood cholestasis. European Journal of Pediatrics. 167: 1339-42. PMID 18270735 DOI: 10.1007/s00431-008-0675-4  0.04
2007 Wu ZM, Ni JJ, Ling SC. [Substance P and/or calcitonin gene-related peptide immunoreactive neurons in dorsal root ganglia possibly involved in the transmission of nociception in rat penile frenulum]. Zhonghua Nan Ke Xue = National Journal of Andrology. 13: 1068-71. PMID 18284051  0.01
2007 Ling SC. Congenital cholestatic syndromes: what happens when children grow up? Canadian Journal of Gastroenterology = Journal Canadien De Gastroenterologie. 21: 743-51. PMID 18026579  0.04
2007 O'Shea AM, Wilson GJ, Ling SC, Minassian BA, Turnbull J, Cutz E. Lafora-like ground-glass inclusions in hepatocytes of pediatric patients: a report of two cases. Pediatric and Developmental Pathology : the Official Journal of the Society For Pediatric Pathology and the Paediatric Pathology Society. 10: 351-7. PMID 17929993 DOI: 10.2350/06-12-01948.1  0.04
2007 Aspelund G, Ling SC, Ng V, Kim PC. A role for laparoscopic approach in the treatment of biliary atresia and choledochal cysts. Journal of Pediatric Surgery. 42: 869-72. PMID 17502202 DOI: 10.1016/j.jpedsurg.2006.12.052  0.01
2007 Sun JG, Han S, Ji H, Zheng Y, Ling SC. [Expression of RAG-1 in brain during mouse development]. Zhejiang Da Xue Xue Bao. Yi Xue Ban = Journal of Zhejiang University. Medical Sciences. 36: 161-6. PMID 17443905  0.01
2006 Muise AM, Turner D, Wine E, Kim P, Marcon M, Ling SC. Biliary atresia with choledochal cyst: implications for classification. Clinical Gastroenterology and Hepatology : the Official Clinical Practice Journal of the American Gastroenterological Association. 4: 1411-4. PMID 16979949 DOI: 10.1016/j.cgh.2006.07.005  0.04
2006 Ha SY, Chik KW, Ling SC, Lee AC, Luk CW, Lam CW, Ng IO, Chan GC. A randomized controlled study evaluating the safety and efficacy of deferiprone treatment in thalassemia major patients from Hong Kong. Hemoglobin. 30: 263-74. PMID 16798652 DOI: 10.1080/03630260600642617  0.01
2006 Li CK, Chik KW, Ha SY, Lee AC, Yuen HL, Ling SC, Lee V, Chan GC, Shing MM, Chan LC, Ng MH. Improved outcome of acute lymphoblastic leukaemia treated by delayed intensification in Hong Kong children: HKALL97 study. Hong Kong Medical Journal = Xianggang Yi Xue Za Zhi / Hong Kong Academy of Medicine. 12: 33-9. PMID 16495587  0.04
2006 Ling SC. Novel therapeutic targets for prevention of portal-systemic collaterals in portal hypertension. Journal of Pediatric Gastroenterology and Nutrition. 42: 121-2. PMID 16385272  0.04
2005 Ling SC. Should children with esophageal varices receive beta-blockers for the primary prevention of variceal hemorrhage? Canadian Journal of Gastroenterology = Journal Canadien De Gastroenterologie. 19: 661-6. PMID 16292360  0.04
2005 Holland J, Cada M, Ling SC, Capra ML, Bernstein S. Melena: a rare presentation of childhood Burkitt's lymphoma. Cmaj : Canadian Medical Association Journal = Journal De L'Association Medicale Canadienne. 173: 247-8. PMID 16076817 DOI: 10.1503/cmaj.050671  0.01
2005 Ng WH, Chu WC, Shing MK, Lam WW, Chik KW, Li CK, Li CK, Ling SC. Role of imaging in management of hemophilic patients. Ajr. American Journal of Roentgenology. 184: 1619-23. PMID 15855127 DOI: 10.2214/ajr.184.5.01841619  0.01
2004 Poon WT, Ling SC, Chan AY, Mak TW. Use of hair analysis in the diagnosis of heavy metal poisoning: report of three cases. Hong Kong Medical Journal = Xianggang Yi Xue Za Zhi / Hong Kong Academy of Medicine. 10: 197-200. PMID 15181225  0.01
2004 Ahmed SF, Horrocks IA, Patterson T, Zaidi S, Ling SC, McGrogan P, Weaver LT. Bone mineral assessment by dual energy X-ray absorptiometry in children with inflammatory bowel disease: evaluation by age or bone area. Journal of Pediatric Gastroenterology and Nutrition. 38: 276-80. PMID 15076625  0.01
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