Daniel M. Skovronsky, Ph.D. - Publications

Affiliations: 
2000 University of Pennsylvania, Philadelphia, PA, United States 
Area:
tau, dementia, neurodegeneration

94/94 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Sims JR, Zimmer JA, Evans CD, Lu M, Ardayfio P, Sparks J, Wessels AM, Shcherbinin S, Wang H, Monkul Nery ES, Collins EC, Solomon P, Salloway S, Apostolova LG, Hansson O, ... ... Skovronsky DM, et al. Donanemab in Early Symptomatic Alzheimer Disease: The TRAILBLAZER-ALZ 2 Randomized Clinical Trial. Jama. PMID 37459141 DOI: 10.1001/jama.2023.13239  0.612
2021 Dougan M, Azizad M, Mocherla B, Gottlieb RL, Chen P, Hebert C, Perry R, Boscia J, Heller B, Morris J, Crystal C, Igbinadolor A, Huhn G, Cardona J, Shawa I, ... ... Skovronsky DM, et al. A randomized, placebo-controlled clinical trial of bamlanivimab and etesevimab together in high-risk ambulatory patients with COVID-19 and validation of the prognostic value of persistently high viral load. Clinical Infectious Diseases : An Official Publication of the Infectious Diseases Society of America. PMID 34718468 DOI: 10.1093/cid/ciab912  0.534
2021 Dougan M, Nirula A, Azizad M, Mocherla B, Gottlieb RL, Chen P, Hebert C, Perry R, Boscia J, Heller B, Morris J, Crystal C, Igbinadolor A, Huhn G, Cardona J, ... ... Skovronsky DM, et al. Bamlanivimab plus Etesevimab in Mild or Moderate Covid-19. The New England Journal of Medicine. PMID 34260849 DOI: 10.1056/NEJMoa2102685  0.546
2021 Cohen MS, Nirula A, Mulligan MJ, Novak RM, Marovich M, Yen C, Stemer A, Mayer SM, Wohl D, Brengle B, Montague BT, Frank I, McCulloh RJ, Fichtenbaum CJ, Lipson B, ... ... Skovronsky DM, et al. Effect of Bamlanivimab vs Placebo on Incidence of COVID-19 Among Residents and Staff of Skilled Nursing and Assisted Living Facilities: A Randomized Clinical Trial. Jama. PMID 34081073 DOI: 10.1001/jama.2021.8828  0.524
2021 Mintun MA, Lo AC, Duggan Evans C, Wessels AM, Ardayfio PA, Andersen SW, Shcherbinin S, Sparks J, Sims JR, Brys M, Apostolova LG, Salloway SP, Skovronsky DM. Donanemab in Early Alzheimer's Disease. The New England Journal of Medicine. PMID 33720637 DOI: 10.1056/NEJMoa2100708  0.654
2021 Gottlieb RL, Nirula A, Chen P, Boscia J, Heller B, Morris J, Huhn G, Cardona J, Mocherla B, Stosor V, Shawa I, Kumar P, Adams AC, Van Naarden J, Custer KL, ... ... Skovronsky DM, et al. Effect of Bamlanivimab as Monotherapy or in Combination With Etesevimab on Viral Load in Patients With Mild to Moderate COVID-19: A Randomized Clinical Trial. Jama. PMID 33475701 DOI: 10.1001/jama.2021.0202  0.555
2020 Nirula A, Shen L, Skovronsky DM. Neutralizing Antibody LY-CoV555 for Outpatient Covid-19. Reply. The New England Journal of Medicine. 384. PMID 33378611 DOI: 10.1056/NEJMc2033787#sa2  0.517
2020 Chen P, Nirula A, Heller B, Gottlieb RL, Boscia J, Morris J, Huhn G, Cardona J, Mocherla B, Stosor V, Shawa I, Adams AC, Van Naarden J, Custer KL, Shen L, ... ... Skovronsky DM, et al. SARS-CoV-2 Neutralizing Antibody LY-CoV555 in Outpatients with Covid-19. The New England Journal of Medicine. PMID 33113295 DOI: 10.1056/NEJMoa2029849  0.528
2016 Grundman M, Johnson KA, Lu M, Siderowf A, Dell'Agnello G, Arora AK, Skovronsky DM, Mintun MA, Pontecorvo MJ. Effect of Amyloid Imaging on the Diagnosis and Management of Patients with Cognitive Decline: Impact of Appropriate Use Criteria. Dementia and Geriatric Cognitive Disorders. 41: 80-92. PMID 26745445 DOI: 10.1159/000441139  0.687
2015 Joshi AD, Pontecorvo MJ, Skovronsky DM, Mintun MA, Lu M, Devous MD. A semi-automated method for quantification of florbetapir F 18 PET images. Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. PMID 26338898 DOI: 10.2967/jnumed.114.153494  0.699
2015 Klunk WE, Koeppe RA, Price JC, Benzinger TL, Devous MD, Jagust WJ, Johnson KA, Mathis CA, Minhas D, Pontecorvo MJ, Rowe CC, Skovronsky DM, Mintun MA. The Centiloid Project: standardizing quantitative amyloid plaque estimation by PET. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. 11: 1-15.e1-4. PMID 25443857 DOI: 10.1016/J.Jalz.2014.07.003  0.659
2015 Tateno A, Sakayori T, Kawashima Y, Higuchi M, Suhara T, Mizumura S, Mintun MA, Skovronsky DM, Honjo K, Ishihara K, Kumita S, Suzuki H, Okubo Y. Comparison of imaging biomarkers for Alzheimer's disease: amyloid imaging with [18F]florbetapir positron emission tomography and magnetic resonance imaging voxel-based analysis for entorhinal cortex atrophy. International Journal of Geriatric Psychiatry. 30: 505-13. PMID 25043833 DOI: 10.1002/gps.4173  0.69
2014 Siderowf A, Pontecorvo MJ, Shill HA, Mintun MA, Arora A, Joshi AD, Lu M, Adler CH, Galasko D, Liebsack C, Skovronsky DM, Sabbagh MN. PET imaging of amyloid with Florbetapir F 18 and PET imaging of dopamine degeneration with 18F-AV-133 (florbenazine) in patients with Alzheimer's disease and Lewy body disorders. Bmc Neurology. 14: 79. PMID 24716655 DOI: 10.1186/1471-2377-14-79  0.691
2014 Doraiswamy PM, Sperling RA, Johnson K, Reiman EM, Wong TZ, Sabbagh MN, Sadowsky CH, Fleisher AS, Carpenter A, Joshi AD, Lu M, Grundman M, Mintun MA, Skovronsky DM, Pontecorvo MJ, et al. Florbetapir F 18 amyloid PET and 36-month cognitive decline: a prospective multicenter study. Molecular Psychiatry. 19: 1044-51. PMID 24614494 DOI: 10.1038/Mp.2014.9  0.645
2014 Joshi AD, Pontecorvo MJ, Adler L, Stabin MG, Skovronsky DM, Carpenter AP, Mintun MA. Radiation dosimetry of florbetapir F 18. Ejnmmi Research. 4: 4. PMID 24401181 DOI: 10.1186/2191-219X-4-4  0.647
2014 Dugger BN, Clark CM, Serrano G, Mariner M, Bedell BJ, Coleman RE, Doraiswamy PM, Lu M, Fleisher AS, Reiman EM, Sabbagh MN, Sadowsky CH, Schneider JA, Zehntner SP, Carpenter AP, ... ... Skovronsky DM, et al. Neuropathologic heterogeneity does not impair florbetapir-positron emission tomography postmortem correlates. Journal of Neuropathology and Experimental Neurology. 73: 72-80. PMID 24335535 DOI: 10.1097/Nen.0000000000000028  0.706
2013 Rosenberg PB, Wong DF, Edell SL, Ross JS, Joshi AD, BraÅ¡ić JR, Zhou Y, Raymont V, Kumar A, Ravert HT, Dannals RF, Pontecorvo MJ, Skovronsky DM, Lyketsos CG. Cognition and amyloid load in Alzheimer disease imaged with florbetapir F 18(AV-45) positron emission tomography. The American Journal of Geriatric Psychiatry : Official Journal of the American Association For Geriatric Psychiatry. 21: 272-8. PMID 23395194 DOI: 10.1016/J.Jagp.2012.11.016  0.712
2013 Johnson KA, Sperling RA, Gidicsin CM, Carmasin JS, Maye JE, Coleman RE, Reiman EM, Sabbagh MN, Sadowsky CH, Fleisher AS, Murali Doraiswamy P, Carpenter AP, Clark CM, Joshi AD, Lu M, ... ... Skovronsky DM, et al. Florbetapir (F18-AV-45) PET to assess amyloid burden in Alzheimer's disease dementia, mild cognitive impairment, and normal aging. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. 9: S72-83. PMID 23375563 DOI: 10.1016/J.Jalz.2012.10.007  0.708
2013 Grundman M, Pontecorvo MJ, Salloway SP, Doraiswamy PM, Fleisher AS, Sadowsky CH, Nair AK, Siderowf A, Lu M, Arora AK, Agbulos A, Flitter ML, Krautkramer MJ, Sarsour K, Skovronsky DM, et al. Potential impact of amyloid imaging on diagnosis and intended management in patients with progressive cognitive decline. Alzheimer Disease and Associated Disorders. 27: 4-15. PMID 23203162 DOI: 10.1097/Wad.0B013E318279D02A  0.687
2013 Sperling RA, Johnson KA, Doraiswamy PM, Reiman EM, Fleisher AS, Sabbagh MN, Sadowsky CH, Carpenter A, Davis MD, Lu M, Flitter M, Joshi AD, Clark CM, Grundman M, Mintun MA, ... Skovronsky DM, et al. Amyloid deposition detected with florbetapir F 18 ((18)F-AV-45) is related to lower episodic memory performance in clinically normal older individuals. Neurobiology of Aging. 34: 822-31. PMID 22878163 DOI: 10.1016/j.neurobiolaging.2012.06.014  0.681
2013 Fleisher AS, Chen K, Liu X, Ayutyanont N, Roontiva A, Thiyyagura P, Protas H, Joshi AD, Sabbagh M, Sadowsky CH, Sperling RA, Clark CM, Mintun MA, Pontecorvo MJ, Coleman RE, ... ... Skovronsky DM, et al. Apolipoprotein E ε4 and age effects on florbetapir positron emission tomography in healthy aging and Alzheimer disease. Neurobiology of Aging. 34: 1-12. PMID 22633529 DOI: 10.1016/J.Neurobiolaging.2012.04.017  0.667
2013 Kolb H, Attardo G, Mintun M, Chien D, Elizarov A, Conti P, Miller C, Joshi A, Skovronsky D. DT-02-01: First case report: Image to autopsy correlation for tau imaging with [18F]-T808 (AV-680) Alzheimer's & Dementia. 9: P844-P845. DOI: 10.1016/J.Jalz.2013.08.008  0.633
2013 Witte M, Dugger B, Serrano G, Bedell BJ, Doraiswamy PM, Fleisher AS, Reiman E, Sabbagh MN, Sadowsky CH, Schneider JA, Carpenter AP, Joshi AD, Mintun MA, Pontecorvo MJ, Skovronsky DM, et al. Florbetapir PET Imaging Predicts Postmortem Amyloid Burden in Alzheimer's Disease Despite Presence of Other Neuropathologies The American Journal of Geriatric Psychiatry. 21: S138-S139. DOI: 10.1016/J.Jagp.2012.12.183  0.722
2013 Hochstetler H, Doraiswamy PM, Sperling RA, Johnson KA, Reiman E, Sabbagh MN, Sadowsky CH, Joshi AD, Lu M, Mintun MA, Pontecorvo MJ, Skovronsky DM. Relationship of Florbetapir F18 PET Amyloid Plaque Neuroimaging with Future Cognitive Decline over 36 Months The American Journal of Geriatric Psychiatry. 21: S136. DOI: 10.1016/j.jagp.2012.12.180  0.672
2012 Doraiswamy PM, Sperling RA, Coleman RE, Johnson KA, Reiman EM, Davis MD, Grundman M, Sabbagh MN, Sadowsky CH, Fleisher AS, Carpenter A, Clark CM, Joshi AD, Mintun MA, Skovronsky DM, et al. Amyloid-β assessed by florbetapir F 18 PET and 18-month cognitive decline: a multicenter study. Neurology. 79: 1636-44. PMID 22786606 DOI: 10.1212/Wnl.0B013E3182661F74  0.704
2012 Clark CM, Pontecorvo MJ, Beach TG, Bedell BJ, Coleman RE, Doraiswamy PM, Fleisher AS, Reiman EM, Sabbagh MN, Sadowsky CH, Schneider JA, Arora A, Carpenter AP, Flitter ML, Joshi AD, ... ... Skovronsky DM, et al. Cerebral PET with florbetapir compared with neuropathology at autopsy for detection of neuritic amyloid-β plaques: a prospective cohort study. The Lancet. Neurology. 11: 669-78. PMID 22749065 DOI: 10.1016/S1474-4422(12)70142-4  0.712
2012 Normandin MD, Petersen KF, Ding YS, Lin SF, Naik S, Fowles K, Skovronsky DM, Herold KC, McCarthy TJ, Calle RA, Carson RE, Treadway JL, Cline GW. In vivo imaging of endogenous pancreatic β-cell mass in healthy and type 1 diabetic subjects using 18F-fluoropropyl-dihydrotetrabenazine and PET. Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. 53: 908-16. PMID 22573821 DOI: 10.2967/Jnumed.111.100545  0.664
2012 Choi SR, Schneider JA, Bennett DA, Beach TG, Bedell BJ, Zehntner SP, Krautkramer MJ, Kung HF, Skovronsky DM, Hefti F, Clark CM. Correlation of amyloid PET ligand florbetapir F 18 binding with Aβ aggregation and neuritic plaque deposition in postmortem brain tissue. Alzheimer Disease and Associated Disorders. 26: 8-16. PMID 22354138 DOI: 10.1097/Wad.0B013E31821300Bc  0.736
2012 Joshi AD, Pontecorvo MJ, Clark CM, Carpenter AP, Jennings DL, Sadowsky CH, Adler LP, Kovnat KD, Seibyl JP, Arora A, Saha K, Burns JD, Lowrey MJ, Mintun MA, Skovronsky DM, et al. Performance characteristics of amyloid PET with florbetapir F 18 in patients with alzheimer's disease and cognitively normal subjects. Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. 53: 378-84. PMID 22331215 DOI: 10.2967/Jnumed.111.090340  0.711
2012 Villemagne VL, Okamura N, Pejoska S, Drago J, Mulligan RS, Chételat G, O'Keefe G, Jones G, Kung HF, Pontecorvo M, Masters CL, Skovronsky DM, Rowe CC. Differential diagnosis in Alzheimer's disease and dementia with Lewy bodies via VMAT2 and amyloid imaging. Neuro-Degenerative Diseases. 10: 161-5. PMID 22261520 DOI: 10.1159/000334535  0.734
2012 Skovronsky D, Beach T, Bedell B, Coleman E, Reiman E, Schneider J, Joshi A, Mintun M, Pontecorvo M, Clark C. O1-04-03: Comparison of florbetapir-PET scans to postmortem beta-amyloid histopathology in 59 autopsy cases Alzheimer's & Dementia. 8: P90-P91. DOI: 10.1016/J.Jalz.2012.05.222  0.627
2011 Virostko J, Henske J, Vinet L, Lamprianou S, Dai C, Radhika A, Baldwin RM, Ansari MS, Hefti F, Skovronsky D, Kung HF, Herrera PL, Peterson TE, Meda P, Powers AC. Multimodal image coregistration and inducible selective cell ablation to evaluate imaging ligands. Proceedings of the National Academy of Sciences of the United States of America. 108: 20719-24. PMID 22143775 DOI: 10.1073/Pnas.1109480108  0.686
2011 Sabbagh MN, Fleisher A, Chen K, Rogers J, Berk C, Reiman E, Pontecorvo M, Mintun M, Skovronsky D, Jacobson SA, Sue LI, Liebsack C, Charney AS, Cole L, Belden C, et al. Positron emission tomography and neuropathologic estimates of fibrillar amyloid-β in a patient with Down syndrome and Alzheimer disease. Archives of Neurology. 68: 1461-6. PMID 22084131 DOI: 10.1001/Archneurol.2011.535  0.71
2011 Zha Z, Choi SR, Ploessl K, Lieberman BP, Qu W, Hefti F, Mintun M, Skovronsky D, Kung HF. Multidentate (18)F-polypegylated styrylpyridines as imaging agents for Aβ plaques in cerebral amyloid angiopathy (CAA). Journal of Medicinal Chemistry. 54: 8085-98. PMID 22011144 DOI: 10.1021/Jm2009106  0.717
2011 Tsao HH, Skovronsky DM, Lin KJ, Yen TC, Wey SP, Kung MP. Sigma receptor binding of tetrabenazine series tracers targeting VMAT2 in rat pancreas. Nuclear Medicine and Biology. 38: 1029-34. PMID 21982574 DOI: 10.1016/J.Nucmedbio.2011.03.006  0.643
2011 Lin KJ, Lin WY, Hsieh CJ, Weng YH, Wey SP, Lu CS, Skovronsky D, Yen TC, Chang CJ, Kung MP, Hsiao IT. Optimal scanning time window for 18F-FP-(+)-DTBZ (18F-AV-133) summed uptake measurements. Nuclear Medicine and Biology. 38: 1149-55. PMID 21831650 DOI: 10.1016/J.Nucmedbio.2011.05.010  0.624
2011 Villemagne VL, Okamura N, Pejoska S, Drago J, Mulligan RS, Chételat G, Ackermann U, O'Keefe G, Jones G, Gong S, Tochon-Danguy H, Kung HF, Masters CL, Skovronsky DM, Rowe CC. In vivo assessment of vesicular monoamine transporter type 2 in dementia with lewy bodies and Alzheimer disease. Archives of Neurology. 68: 905-12. PMID 21747030 DOI: 10.1001/Archneurol.2011.142  0.705
2011 Fleisher AS, Chen K, Liu X, Roontiva A, Thiyyagura P, Ayutyanont N, Joshi AD, Clark CM, Mintun MA, Pontecorvo MJ, Doraiswamy PM, Johnson KA, Skovronsky DM, Reiman EM. Using positron emission tomography and florbetapir F18 to image cortical amyloid in patients with mild cognitive impairment or dementia due to Alzheimer disease. Archives of Neurology. 68: 1404-11. PMID 21747008 DOI: 10.1001/Archneurol.2011.150  0.728
2011 Lister-James J, Pontecorvo MJ, Clark C, Joshi AD, Mintun MA, Zhang W, Lim N, Zhuang Z, Golding G, Choi SR, Benedum TE, Kennedy P, Hefti F, Carpenter AP, Kung HF, ... Skovronsky DM, et al. Florbetapir f-18: a histopathologically validated Beta-amyloid positron emission tomography imaging agent. Seminars in Nuclear Medicine. 41: 300-4. PMID 21624563 DOI: 10.1053/J.Semnuclmed.2011.03.001  0.721
2011 Clark CM, Schneider JA, Bedell BJ, Beach TG, Bilker WB, Mintun MA, Pontecorvo MJ, Hefti F, Carpenter AP, Flitter ML, Krautkramer MJ, Kung HF, Coleman RE, Doraiswamy PM, Fleisher AS, ... ... Skovronsky DM, et al. Use of florbetapir-PET for imaging beta-amyloid pathology. Jama. 305: 275-83. PMID 21245183 DOI: 10.1001/Jama.2010.2008  0.739
2011 Skovronsky D. Amyloid imaging with 18F-AV-45 (florbetapir F 18) Neuroscience Research. 71: e39. DOI: 10.1016/j.neures.2011.07.173  0.665
2011 Pontecorvo MJ, Joshi A, Skovronsky D, Clark C, Mintun M. O4-07-03: Florbetapir PET correlates with cognitive decline, PIB PET and CSF markers in the ADNI database Alzheimer's & Dementia. 7: S697-S697. DOI: 10.1016/j.jalz.2011.05.2014  0.602
2010 Hefti FF, Kung HF, Kilbourn MR, Carpenter AP, Clark CM, Skovronsky DM. (18)F-AV-133: A Selective VMAT2-binding Radiopharmaceutical for PET Imaging of Dopaminergic Neurons. Pet Clinics. 5: 75-82. PMID 27157484 DOI: 10.1016/J.Cpet.2010.02.001  0.68
2010 Lin KJ, Weng YH, Wey SP, Hsiao IT, Lu CS, Skovronsky D, Chang HP, Kung MP, Yen TC. Whole-body biodistribution and radiation dosimetry of 18F-FP-(+)-DTBZ (18F-AV-133): a novel vesicular monoamine transporter 2 imaging agent. Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. 51: 1480-5. PMID 20720042 DOI: 10.2967/Jnumed.110.078196  0.677
2010 Yao CH, Lin KJ, Weng CC, Hsiao IT, Ting YS, Yen TC, Jan TR, Skovronsky D, Kung MP, Wey SP. GMP-compliant automated synthesis of [(18)F]AV-45 (Florbetapir F 18) for imaging beta-amyloid plaques in human brain. Applied Radiation and Isotopes : Including Data, Instrumentation and Methods For Use in Agriculture, Industry and Medicine. 68: 2293-7. PMID 20638295 DOI: 10.1016/J.Apradiso.2010.07.001  0.707
2010 Wong DF, Rosenberg PB, Zhou Y, Kumar A, Raymont V, Ravert HT, Dannals RF, Nandi A, Brasić JR, Ye W, Hilton J, Lyketsos C, Kung HF, Joshi AD, Skovronsky DM, et al. In vivo imaging of amyloid deposition in Alzheimer disease using the radioligand 18F-AV-45 (florbetapir [corrected] F 18). Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. 51: 913-20. PMID 20501908 DOI: 10.2967/Jnumed.109.069088  0.738
2010 Jagust WJ, Bandy D, Chen K, Foster NL, Landau SM, Mathis CA, Price JC, Reiman EM, Skovronsky D, Koeppe RA. The Alzheimer's Disease Neuroimaging Initiative positron emission tomography core. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. 6: 221-9. PMID 20451870 DOI: 10.1016/J.Jalz.2010.03.003  0.716
2010 Lin KJ, Hsu WC, Hsiao IT, Wey SP, Jin LW, Skovronsky D, Wai YY, Chang HP, Lo CW, Yao CH, Yen TC, Kung MP. Whole-body biodistribution and brain PET imaging with [18F]AV-45, a novel amyloid imaging agent--a pilot study. Nuclear Medicine and Biology. 37: 497-508. PMID 20447562 DOI: 10.1016/j.nucmedbio.2010.02.003  0.714
2010 Tsao HH, Lin KJ, Juang JH, Skovronsky DM, Yen TC, Wey SP, Kung MP. Binding characteristics of 9-fluoropropyl-(+)-dihydrotetrabenzazine (AV-133) to the vesicular monoamine transporter type 2 in rats. Nuclear Medicine and Biology. 37: 413-9. PMID 20447551 DOI: 10.1016/J.Nucmedbio.2010.01.002  0.643
2010 Okamura N, Villemagne VL, Drago J, Pejoska S, Dhamija RK, Mulligan RS, Ellis JR, Ackermann U, O'Keefe G, Jones G, Kung HF, Pontecorvo MJ, Skovronsky D, Rowe CC. In vivo measurement of vesicular monoamine transporter type 2 density in Parkinson disease with (18)F-AV-133. Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. 51: 223-8. PMID 20080893 DOI: 10.2967/Jnumed.109.070094  0.659
2010 Kung HF, Choi SR, Qu W, Zhang W, Skovronsky D. 18F stilbenes and styrylpyridines for PET imaging of Aβ plaques in Alzheimer's disease: A miniperspective Journal of Medicinal Chemistry. 53: 933-941. PMID 19845387 DOI: 10.1021/Jm901039Z  0.719
2010 Sperling RA, Doraiswamy PM, Johnson K, Reiman EM, Sabbagh MN, Sadowsky CH, Carpenter A, Clark CM, Flitter M, Pontecorvo MJ, Skovronsky DM. O1-02-04: Florbetapir F 18 (18 F-AV-45) PET amyloid imaging predicts progression of cognitive impairment: A longitudinal clinical follow up study Alzheimer's & Dementia. 6: S71-S71. DOI: 10.1016/J.Jalz.2010.05.212  0.667
2010 Hefti FF, Kung HF, Kilbourn MR, Carpenter AP, Clark CM, Skovronsky DM. 18F-AV-133: A selective VMAT2-binding radiopharmaceutical for PET imaging of dopaminergic neurons Pet Clinics. 5: 75-82. DOI: 10.1016/j.cpet.2010.02.001  0.643
2009 Choi SR, Golding G, Zhuang Z, Zhang W, Lim N, Hefti F, Benedum TE, Kilbourn MR, Skovronsky D, Kung HF. Preclinical properties of 18F-AV-45: a PET agent for Abeta plaques in the brain. Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. 50: 1887-94. PMID 19837759 DOI: 10.2967/Jnumed.109.065284  0.74
2009 Carpenter AP, Pontecorvo MJ, Hefti FF, Skovronsky DM. The use of the exploratory IND in the evaluation and development of 18F-PET radiopharmaceuticals for amyloid imaging in the brain: a review of one company's experience. The Quarterly Journal of Nuclear Medicine and Molecular Imaging : Official Publication of the Italian Association of Nuclear Medicine (Aimn) [and] the International Association of Radiopharmacology (Iar), [and] Section of the Society of Radiopharmaceutical Chemistry and Biology. 53: 387-93. PMID 19834448  0.713
2009 Wey SP, Weng CC, Lin KJ, Yao CH, Yen TC, Kung HF, Skovronsky D, Kung MP. Validation of an (18)F-labeled biphenylalkyne as a positron emission tomography imaging agent for beta-amyloid plaques. Nuclear Medicine and Biology. 36: 411-7. PMID 19423009 DOI: 10.1016/J.Nucmedbio.2009.01.013  0.726
2009 Doraiswamy PM, Farmer M, Holub R, Johnson K, Reiman EM, Sadowsky C, Safirstein B, Spicer K, Carpenter A, Clark CM, Joshi A, Veeraraj C, Pontecorvo MJ, Skovronsky D. O1-01-03: Relationship between regional amyloid levels and cognitive performance in healthy controls, MCI subjects, and patients with alzheimer's: Phase II results from a florpiramine F18 PET imaging study Alzheimer's & Dementia. 5: P77-P77. DOI: 10.1016/J.Jalz.2009.05.189  0.673
2009 Sperling R, Johnson K, Pontecorvo MJ, Safirstein B, Farmer M, Holub R, Korn R, Spicer K, Doraiswamy M, Reiman EM, Joshi A, Saha K, Flitter M, Clark CM, Skovronsky DM. P1-084: PET imaging of β-amyloid with florpiramine F18 (18F-AV-45): Preliminary results from a phase II study of cognitively normal elderly subjects, individuals with mild cognitive impairment, and patients with a clinical diagnosis of Alzheimer's disease Alzheimer's & Dementia. 5: P197-P197. DOI: 10.1016/J.Jalz.2009.04.088  0.675
2008 Kung HF, Lieberman BP, Zhuang ZP, Oya S, Kung MP, Choi SR, Poessl K, Blankemeyer E, Hou C, Skovronsky D, Kilbourn M. In vivo imaging of vesicular monoamine transporter 2 in pancreas using an (18)F epoxide derivative of tetrabenazine. Nuclear Medicine and Biology. 35: 825-37. PMID 19026944 DOI: 10.1016/J.Nucmedbio.2008.08.004  0.656
2008 Qu W, Choi SR, Hou C, Zhuang Z, Oya S, Zhang W, Kung MP, Manchandra R, Skovronsky DM, Kung HF. Synthesis and evaluation of indolinyl- and indolylphenylacetylenes as PET imaging agents for beta-amyloid plaques. Bioorganic & Medicinal Chemistry Letters. 18: 4823-7. PMID 18707879 DOI: 10.1016/J.Bmcl.2008.07.077  0.701
2008 Kung MP, Hou C, Lieberman BP, Oya S, Ponde DE, Blankemeyer E, Skovronsky D, Kilbourn MR, Kung HF. In vivo imaging of β-cell mass in rats using 18F-FP-(+)- DTBZ: A potential PET ligand for studying diabetes mellitus Journal of Nuclear Medicine. 49: 1171-1176. PMID 18552132 DOI: 10.2967/Jnumed.108.051680  0.677
2008 Skovronsky D. Use of eINDs for evaluation of multiple related PET amyloid plaque imaging agents Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. 49: 47N-48N. PMID 18511825  0.675
2008 Rowe CC, Ackerman U, Browne W, Mulligan R, Pike KL, O'Keefe G, Tochon-Danguy H, Chan G, Berlangieri SU, Jones G, Dickinson-Rowe KL, Kung HP, Zhang W, Kung MP, Skovronsky D, et al. Imaging of amyloid beta in Alzheimer's disease with 18F-BAY94-9172, a novel PET tracer: proof of mechanism. The Lancet. Neurology. 7: 129-35. PMID 18191617 DOI: 10.1016/S1474-4422(08)70001-2  0.724
2008 Rosenberg PB, Zhou Y, Kumar A, Ravert H, Brasic J, Ye W, Alexander M, Dannals R, Galecki J, Lyketsos C, Skovronsky D, Pontecorvo M, Wong DF. P1-284: In vivo imaging of amyloid deposition in Alzheimer's disease using the novel radioligand [18 F] Av-45 Alzheimer's & Dementia. 4: T300-T301. DOI: 10.1016/J.Jalz.2008.05.874  0.733
2008 Pontecorvo M, Coleman RE, Doraiswamy M, Lowe V, Mintun M, Morris J, Petersen R, Rosenberg P, Ross J, Sadowsky C, Williamson J, Wong D, Carpenter A, Hefti F, Skovronsky D. IC-P3-205: Development of novel 18 F Aβ amyloid imaging agents Alzheimer's & Dementia. 4: T88-T88. DOI: 10.1016/J.Jalz.2008.05.149  0.669
2008 Joshi A, Skovronsky D, Pontecorvo M. P2-025: A semiautomated method for quantification of 18F-labelled amyloid plaque imaging agents based on volume of interest and voxel-based statistical analyses Alzheimer's & Dementia. 4: T374-T375. DOI: 10.1016/J.Jalz.2008.05.1105  0.698
2006 Skovronsky DM, Lee VM, Trojanowski JQ. Neurodegenerative diseases: new concepts of pathogenesis and their therapeutic implications. Annual Review of Pathology. 1: 151-70. PMID 18039111 DOI: 10.1146/Annurev.Pathol.1.110304.100113  0.678
2006 Newberg AB, Wintering NA, Plössl K, Hochold J, Stabin MG, Watson M, Skovronsky D, Clark CM, Kung MP, Kung HF. Safety, biodistribution, and dosimetry of 123I-IMPY: A novel amyloid plaque-imaging agent for the diagnosis of Alzheimer's disease Journal of Nuclear Medicine. 47: 748-754. PMID 16644743  0.663
2006 Clark CM, Newberg AB, Watson M, Wintering NA, Skovronsky DM, Kung HF. P2-343: Imaging amyloid with I123 IMPY SPECT Alzheimers & Dementia. 2. DOI: 10.1016/J.Jalz.2006.05.1183  0.678
2005 Kung M, Hou C, Zhuang Z, Skovronsky D, Kung HF. Erratum to “Binding of two potential imaging agents targeting amyloid plaques in postmortem brain tissues of patients with Alzheimer's disease” [Brain Research 1025 (2004) 98–105] Brain Research. 1031: 302. DOI: 10.1016/J.Brainres.2004.10.002  0.686
2004 Kung MP, Hou C, Zhuang ZP, Skovronsky D, Kung HF. Binding of two potential imaging agents targeting amyloid plaques in postmortem brain tissues of patients with Alzheimer's disease Brain Research. 1025: 98-105. PMID 15464749 DOI: 10.1016/J.Brainres.2004.08.004  0.717
2004 Skovronsky DM, Oberholtzer JC. Pathologic classification of peripheral nerve tumors. Neurosurgery Clinics of North America. 15: 157-66. PMID 15177315 DOI: 10.1016/J.Nec.2004.02.005  0.568
2004 Skovronsky D, Judkins AR, Kung M, Forman M, Martinez D, Hou C, Zhuang Z, Kung HF. P3-079 Characterization of neurodegenerative disease radioligands by tissue microarray analysis Neurobiology of Aging. 25: S375-S376. DOI: 10.1016/S0197-4580(04)81231-4  0.711
2004 Hou C, Kung M, Xiu Y, Skovronsky DM, Mach R, Kung HF. P2-188 Labeling amyloid plaque-like structures by radioiodinated ligands in rhesus monkey brain Neurobiology of Aging. 25: S281. DOI: 10.1016/S0197-4580(04)80934-5  0.657
2004 Kung M, Hou C, Zhuang Z, Skovronsky DM, Kung HF. O3-03-02 Binding of two potential imaging agents targeting amyloid plaques in Alzheimer's disease brains Neurobiology of Aging. 25: S57. DOI: 10.1016/S0197-4580(04)80192-1  0.698
2003 Kung HF, Kung MP, Zhuang ZP, Hou C, Lee CW, Plössl K, Zhuang B, Skovronsky DM, Lee VM, Trojanowski JQ. Iodinated tracers for imaging amyloid plaques in the brain. Molecular Imaging and Biology : Mib : the Official Publication of the Academy of Molecular Imaging. 5: 418-26. PMID 14667496 DOI: 10.1016/J.Mibio.2003.09.003  0.768
2003 Kung MP, Skovronsky DM, Hou C, Zhuang ZP, Gur TL, Zhang B, Trojanowski JQ, Lee VM, Kung HF. Detection of amyloid plaques by radioligands for Abeta40 and Abeta42: potential imaging agents in Alzheimer's patients. Journal of Molecular Neuroscience : Mn. 20: 15-24. PMID 12663930 DOI: 10.1385/Jmn:20:1:15  0.747
2003 Lee EB, Skovronsky DM, Abtahian F, Doms RW, Lee VM. Secretion and intracellular generation of truncated Abeta in beta-site amyloid-beta precursor protein-cleaving enzyme expressing human neurons. The Journal of Biological Chemistry. 278: 4458-66. PMID 12480937 DOI: 10.1074/Jbc.M210105200  0.75
2002 Kung MP, Hou C, Zhuang ZP, Zhang B, Skovronsky D, Trojanowski JQ, Lee VMY, Kung HF. IMPY: An improved thioflavin-T derivative for in vivo labeling of β-amyloid plaques Brain Research. 956: 202-210. PMID 12445687 DOI: 10.1016/S0006-8993(02)03436-4  0.716
2002 Saqi A, McGrath CM, Skovronsky D, Yu GH. Cytomorphologic features of fine-needle aspiration of metastatic and recurrent melanoma Diagnostic Cytopathology. 27: 286-290. PMID 12411994 DOI: 10.1002/dc.10194  0.533
2002 Kung MP, Hou C, Zhuang ZP, Skovronsky DM, Zhang B, Gur TL, Trojanowski JQ, Lee VM, Kung HF. Radioiodinated styrylbenzene derivatives as potential SPECT imaging agents for amyloid plaque detection in Alzheimer's disease. Journal of Molecular Neuroscience : Mn. 19: 7-10. PMID 12212796 DOI: 10.1007/S12031-002-0003-9  0.739
2001 Zhuang ZP, Kung MP, Hou C, Plössl K, Skovronsky D, Gur TL, Trojanowski JQ, Lee VM, Kung HF. IBOX(2-(4'-dimethylaminophenyl)-6-iodobenzoxazole): a ligand for imaging amyloid plaques in the brain. Nuclear Medicine and Biology. 28: 887-94. PMID 11711307 DOI: 10.1016/S0969-8051(01)00264-5  0.699
2001 Schmidt ML, Schuck T, Sheridan S, Kung MP, Kung H, Zhuang ZP, Bergeron C, Lamarche JS, Skovronsky D, Giasson BI, Lee VM, Trojanowski JQ. The fluorescent Congo red derivative, (trans, trans)-1-bromo-2,5-bis-(3-hydroxycarbonyl-4-hydroxy)styrylbenzene (BSB), labels diverse beta-pleated sheet structures in postmortem human neurodegenerative disease brains. The American Journal of Pathology. 159: 937-43. PMID 11549586 DOI: 10.1016/S0002-9440(10)61769-5  0.757
2001 Skovronsky DM, Fath S, Lee VM, Milla ME. Neuronal localization of the TNFalpha converting enzyme (TACE) in brain tissue and its correlation to amyloid plaques. Journal of Neurobiology. 49: 40-6. PMID 11536196 DOI: 10.1002/Neu.1064  0.713
2001 Lee CW, Zhuang ZP, Kung MP, Plössl K, Skovronsky D, Gur T, Hou C, Trojanowski JQ, Lee VMY, Kung HF. Isomerization of (Z,Z) to (E,E)1-bromo-2,5-bis-(3- hydroxycarbonyl-4-hydroxy)-styrylbenzene in strong base: Probes for amyloid plaques in the brain Journal of Medicinal Chemistry. 44: 2270-2275. PMID 11428920 DOI: 10.1021/Jm010161T  0.648
2001 Zhuang ZP, Kung MP, Hou C, Skovronsky DM, Gur TL, Plössl K, Trojanowski JQ, Lee VM, Kung HF. Radioiodinated styrylbenzenes and thioflavins as probes for amyloid aggregates. Journal of Medicinal Chemistry. 44: 1905-14. PMID 11384236 DOI: 10.1021/Jm010045Q  0.731
2001 Skovronsky DM, Lee VM, Praticò D. Amyloid precursor protein and amyloid beta peptide in human platelets. Role of cyclooxygenase and protein kinase C. The Journal of Biological Chemistry. 276: 17036-43. PMID 11278299 DOI: 10.1074/Jbc.M006285200  0.711
2000 Skovronsky DM, Wang J, Lee VM, Doms RW. Quantifying Aβ(1-40) and Aβ (1-42) Using Sandwich-ELISA. Methods in Molecular Medicine. 32: 79-89. PMID 21318512 DOI: 10.1385/1-59259-195-7:79  0.717
2000 Skovronsky DM, Zhang B, Kung MP, Kung HF, Trojanowski JQ, Lee VM. In vivo detection of amyloid plaques in a mouse model of Alzheimer's disease. Proceedings of the National Academy of Sciences of the United States of America. 97: 7609-14. PMID 10861023 DOI: 10.1073/Pnas.97.13.7609  0.727
2000 Skovronsky DM, Lee VM. Beta-secretase revealed: starting gate for race to novel therapies for Alzheimer's disease. Trends in Pharmacological Sciences. 21: 161-3. PMID 10785643 DOI: 10.1016/S0165-6147(00)01467-X  0.707
2000 Skovronsky DM, Pijak DS, Doms RW, Lee VM. A distinct ER/IC gamma-secretase competes with the proteasome for cleavage of APP. Biochemistry. 39: 810-7. PMID 10651647 DOI: 10.1021/Bi991728Z  0.712
2000 Skovronsky DM, Moore DB, Milla ME, Doms RW, Lee VM. Protein kinase C-dependent alpha-secretase competes with beta-secretase for cleavage of amyloid-beta precursor protein in the trans-golgi network. The Journal of Biological Chemistry. 275: 2568-75. PMID 10644715 DOI: 10.1074/Jbc.275.4.2568  0.68
1998 Skovronsky DM, Doms RW, Lee VM. Detection of a novel intraneuronal pool of insoluble amyloid beta protein that accumulates with time in culture. The Journal of Cell Biology. 141: 1031-9. PMID 9585420 DOI: 10.1083/Jcb.141.4.1031  0.722
1994 Morgan NS, Skovronsky DM, Artavanis-Tsakonas S, Mooseker MS. The molecular cloning and characterization of Drosophila melanogaster myosin-IA and myosin-IB. Journal of Molecular Biology. 239: 347-56. PMID 8201616 DOI: 10.1006/jmbi.1994.1376  0.533
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