Daniel M. Skovronsky, Ph.D. - Related publications

Affiliations: 
2000 University of Pennsylvania, Philadelphia, PA, United States 
Area:
tau, dementia, neurodegeneration
NOTE: We are testing a new system for identifying relevant work based on semantic analysis that identifies similarities between recently published papers and the current author's publications. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches.
50 most relevant papers in past 60 days:
Year Citation  Score
2021 Li Q, Zhang Y, Liang H, Gong H, Jiang L, Liu Q, Shen L. Deep learning based neuronal soma detection and counting for Alzheimer's disease analysis. Computer Methods and Programs in Biomedicine. 203: 106023. PMID 33744751 DOI: 10.1016/j.cmpb.2021.106023   
2021 Davis N, Mota BC, Stead L, Palmer EOC, Lombardero L, Rodríguez-Puertas R, de Paola V, Barnes SJ, Sastre M. Pharmacological ablation of astrocytes reduces Aβ degradation and synaptic connectivity in an ex vivo model of Alzheimer's disease. Journal of Neuroinflammation. 18: 73. PMID 33731156 DOI: 10.1186/s12974-021-02117-y   
2021 Kobro-Flatmoen A, Lagartos-Donate MJ, Aman Y, Edison P, Witter MP, Fang EF. Re-emphasizing early Alzheimer's disease pathology starting in select entorhinal neurons, with a special focus on mitophagy. Ageing Research Reviews. 101307. PMID 33621703 DOI: 10.1016/j.arr.2021.101307   
2021 Zhang N, Xu H, Wang Y, Yao Y, Liu G, Lei X, Sun H, Wu X, Li J. Protective mechanism of kaempferol against Aβ-mediated apoptosis of pheochromocytoma (PC-12) cells through the ER/ERK/MAPK signalling pathway. Archives of Medical Science : Ams. 17: 406-416. PMID 33747277 DOI: 10.5114/aoms.2020.98199   
2021 Yoo JY, Kim HB, Baik TK, Lee JH, Woo RS. Neuregulin 1/ErbB4/Akt signaling attenuates cytotoxicity mediated by the APP-CT31 fragment of amyloid precursor protein. Experimental and Molecular Pathology. 104622. PMID 33684392 DOI: 10.1016/j.yexmp.2021.104622   
2021 Ulm BS, Borchelt DR, Moore BD. Remodeling Alzheimer-amyloidosis models by seeding. Molecular Neurodegeneration. 16: 8. PMID 33588898 DOI: 10.1186/s13024-021-00429-4   
2021 Soto-Rojas LO, Pacheco-Herrero M, Martínez-Gómez PA, Campa-Córdoba BB, Apátiga-Pérez R, Villegas-Rojas MM, Harrington CR, de la Cruz F, Garcés-Ramírez L, Luna-Muñoz J. The Neurovascular Unit Dysfunction in Alzheimer's Disease. International Journal of Molecular Sciences. 22. PMID 33670754 DOI: 10.3390/ijms22042022   
2021 Paulus A, Engdahl A, Yang Y, Boza-Serrano A, Bachiller S, Torres-Garcia L, Svanbergsson A, Garcia MG, Gouras GK, Li JY, Deierborg T, Klementieva O. Amyloid Structural Changes Studied by Infrared Microspectroscopy in Bigenic Cellular Models of Alzheimer's Disease. International Journal of Molecular Sciences. 22. PMID 33810433 DOI: 10.3390/ijms22073430   
2021 Zimmer JA, Shcherbinin S, Devous MD, Bragg SM, Selzler KJ, Wessels AM, Shering C, Mullen J, Landry J, Andersen SW, Downing AM, Fleisher AS, Svaldi DO, Sims JR. Lanabecestat: Neuroimaging results in early symptomatic Alzheimer's disease. Alzheimer's & Dementia (New York, N. Y.). 7: e12123. PMID 33614894 DOI: 10.1002/trc2.12123   
2021 Yi S, Chen S, Xiang J, Tan J, Huang K, Zhang H, Wang Y, Wu H. Genistein exerts a cell-protective effect via Nrf2/HO-1/PI3K signaling in Aβ25-35-induced Alzheimer's disease models in vitro. Folia Histochemica Et Cytobiologica. PMID 33605427 DOI: 10.5603/FHC.a2021.0006   
2021 Clayton K, Delpech JC, Herron S, Iwahara N, Ericsson M, Saito T, Saido TC, Ikezu S, Ikezu T. Plaque associated microglia hyper-secrete extracellular vesicles and accelerate tau propagation in a humanized APP mouse model. Molecular Neurodegeneration. 16: 18. PMID 33752701 DOI: 10.1186/s13024-021-00440-9   
2021 Hao F, Feng Y. Bulbocodin D ameliorate cognitive impairment in APP/PS1 transgenic mice by modulating amyloid-beta burden, oxidative status and neuroinflammation. Psychopharmacology. PMID 33811504 DOI: 10.1007/s00213-021-05832-9   
2021 Lau JKY, Tian M, Shen Y, Lau SF, Fu WY, Fu AKY, Ip NY. Melanocortin receptor activation alleviates amyloid pathology and glial reactivity in an Alzheimer's disease transgenic mouse model. Scientific Reports. 11: 4359. PMID 33623128 DOI: 10.1038/s41598-021-83932-4   
2021 Sharma VK, Singh TG. CREB: A Multifaceted Target for Alzheimer's Disease. Current Alzheimer Research. PMID 33602089 DOI: 10.2174/1567205018666210218152253   
2021 Abbaszadeh M, Sahin M, Ozgun A, Oncu G, Garipcan B, Saybasili H. A Transient Survival Model of Alteration of Electrophysiological Properties Due to Amyloid-Beta Toxicity Based on SH-SY5Y Cell Line. Current Alzheimer Research. PMID 33583383 DOI: 10.2174/1567205018666210212155750   
2021 Shin J, Yang SH, Du YE, Park K, Kim D, Shin D, Kim J, Kim SH, Kim YK, Shin J, Oh DC, Kim Y. Borrelidin from Saltern-Derived Halophilic sp. Dissociates Amyloid- and Tau Fibrils. Journal of Alzheimer's Disease Reports. 5: 7-13. PMID 33681712 DOI: 10.3233/ADR-200247   
2021 Keshavan A, Wellington H, Chen Z, Khatun A, Chapman M, Hart M, Cash DM, Coath W, Parker TD, Buchanan SM, Keuss SE, Harris MJ, Murray-Smith H, Heslegrave A, Fox NC, et al. Concordance of CSF measures of Alzheimer's pathology with amyloid PET status in a preclinical cohort: A comparison of Lumipulse and established immunoassays. Alzheimer's & Dementia (Amsterdam, Netherlands). 13: e12131. PMID 33598527 DOI: 10.1002/dad2.12131   
2021 Gerrits E, Brouwer N, Kooistra SM, Woodbury ME, Vermeiren Y, Lambourne M, Mulder J, Kummer M, Möller T, Biber K, Dunnen WFAD, De Deyn PP, Eggen BJL, Boddeke EWGM. Distinct amyloid-β and tau-associated microglia profiles in Alzheimer's disease. Acta Neuropathologica. PMID 33609158 DOI: 10.1007/s00401-021-02263-w   
2021 Xing J, Xu C. Role of connexins in neurodegenerative diseases (Review). Molecular Medicine Reports. 23. PMID 33760195 DOI: 10.3892/mmr.2021.12034   
2021 Lee SB, Park A, Ma CT, Kim YH, Yang HO. 3'-O-Acetyl-24-Epi-7,8-Didehydrocimigenol-3-O-β-D-Xylopryranoside Decreases Amyloid Beta Production in Amyloid Precursor Protein-Transfected HeLa Cells. Biomolecules & Therapeutics. PMID 33619237 DOI: 10.4062/biomolther.2020.195   
2021 La Barbera L, Vedele F, Nobili A, Krashia P, Spoleti E, Latagliata EC, Cutuli D, Cauzzi E, Marino R, Viscomi MT, Petrosini L, Puglisi-Allegra S, Melone M, Keller F, Mercuri NB, et al. Nilotinib restores memory function by preventing dopaminergic neuron degeneration in a mouse model of Alzheimer's Disease. Progress in Neurobiology. 102031. PMID 33684513 DOI: 10.1016/j.pneurobio.2021.102031   
2021 Owen JE, Zhu Y, Fenik P, Zhan G, Bell P, Liu C, Veasey S. Late-in-Life Neurodegeneration after Chronic Sleep Loss in Young Adult Mice. Sleep. PMID 33768250 DOI: 10.1093/sleep/zsab057   
2021 Jang M, Choi SH, Choi JH, Oh J, Lee RM, Lee NE, Cho YJ, Rhim H, Kim HC, Cho IH, Nah SY. Ginseng gintonin attenuates the disruptions of brain microvascular permeability and microvascular endothelium junctional proteins in an APPswe/PSEN-1 double-transgenic mouse model of Αlzheimer's disease. Experimental and Therapeutic Medicine. 21: 310. PMID 33717253 DOI: 10.3892/etm.2021.9741   
2021 Cash MK, Rockwood K, Fisk JD, Darvesh S. Clinicopathological correlations and cholinesterase expression in early-onset familial Alzheimer's disease with the presenilin 1 mutation, Leu235Pro. Neurobiology of Aging. 103: 31-41. PMID 33789210 DOI: 10.1016/j.neurobiolaging.2021.02.025   
2021 Zheng X, Lin W, Jiang Y, Lu K, Wei W, Huo Q, Cui S, Yang X, Li M, Xu N, Tang C, Song JX. Electroacupuncture ameliorates beta-amyloid pathology and cognitive impairment in Alzheimer disease via a novel mechanism involving activation of TFEB (transcription factor EB). Autophagy. 1-15. PMID 33622188 DOI: 10.1080/15548627.2021.1886720   
2021 Zhang X, Li J, Ma L, Xu H, Cao Y, Liang W, Ma J, Wang ZP, Li Y. BMP4 overexpression induces the upregulation of APP/Tau and memory deficits in Alzheimer's disease. Cell Death Discovery. 7: 51. PMID 33723239 DOI: 10.1038/s41420-021-00435-x   
2021 Maeda J, Minamihisamatsu T, Shimojo M, Zhou X, Ono M, Matsuba Y, Ji B, Ishii H, Ogawa M, Akatsu H, Kaneda D, Hashizume Y, Robinson JL, Lee VM, Saito T, et al. Distinct microglial response against Alzheimer's amyloid and tau pathologies characterized by P2Y12 receptor. Brain Communications. 3: fcab011. PMID 33644757 DOI: 10.1093/braincomms/fcab011   
2021 Lee JH, Ahn NH, Choi SB, Kwon Y, Yang SH. Natural Products Targeting Amyloid Beta in Alzheimer's Disease. International Journal of Molecular Sciences. 22. PMID 33652858 DOI: 10.3390/ijms22052341   
2021 Tian DY, Cheng Y, Zhuang ZQ, He CY, Pan QG, Tang MZ, Hu XL, Shen YY, Wang YR, Chen SH, Sun HL, Sun PY, Yu ZY, Fan DY, Bu XL, et al. Physiological clearance of amyloid-beta by the kidney and its therapeutic potential for Alzheimer's disease. Molecular Psychiatry. PMID 33828237 DOI: 10.1038/s41380-021-01073-6   
2021 Deng Z, Wang J, Xiao Y, Li F, Niu L, Liu X, Meng L, Zheng H. Ultrasound-mediated augmented exosome release from astrocytes alleviates amyloid-β-induced neurotoxicity. Theranostics. 11: 4351-4362. PMID 33754065 DOI: 10.7150/thno.52436   
2021 Khan A, Das S, Sergi C. Therapeutic Potential of Neu1 in Alzheimer's Disease Via the Immune System. American Journal of Alzheimer's Disease and Other Dementias. 36: 1533317521996147. PMID 33719595 DOI: 10.1177/1533317521996147   
2021 Wegmann S, DeVos SL, Zeitler B, Marlen K, Bennett RE, Perez-Rando M, MacKenzie D, Yu Q, Commins C, Bannon RN, Corjuc BT, Chase A, Diez L, Nguyen HB, Hinkley S, et al. Persistent repression of tau in the brain using engineered zinc finger protein transcription factors. Science Advances. 7. PMID 33741591 DOI: 10.1126/sciadv.abe1611   
2021 Shin JH, Hwang YS, Jung BK, Seo SH, Ham DW, Shin EH. Reduction of Amyloid Burden by Proliferated Homeostatic Microglia in -Infected Alzheimer's Disease Model Mice. International Journal of Molecular Sciences. 22. PMID 33803262 DOI: 10.3390/ijms22052764   
2021 Lu MH, Ji WL, Chen H, Sun YY, Zhao XY, Wang F, Shi Y, Hu YN, Liu BX, Wu JW, Xu DE, Zheng JW, Liu CF, Ma QH. Intranasal Transplantation of Human Neural Stem Cells Ameliorates Alzheimer's Disease-Like Pathology in a Mouse Model. Frontiers in Aging Neuroscience. 13: 650103. PMID 33776747 DOI: 10.3389/fnagi.2021.650103   
2021 Chan EWL, Yeo ETY, Wong KWL, See ML, Wong KY, Yap JKY, Gan SY. Piper sarmentosum Roxb. Attenuates Beta Amyloid (Aβ)-Induced Neurotoxicity Via the Inhibition of Amyloidogenesis and Tau Hyperphosphorylation in SH-SY5Y Cells. Current Alzheimer Research. PMID 33761853 DOI: 10.2174/1567205018666210324124239   
2021 Brown A, Török M. Functional amyloids in the human body. Bioorganic & Medicinal Chemistry Letters. 127914. PMID 33691165 DOI: 10.1016/j.bmcl.2021.127914   
2021 Sun H, Zhong Y, Zhu X, Liao H, Lee J, Chen Y, Ma L, Ren J, Zhao M, Tu M, Li F, Zhang H, Tian M, Ling D. A Tauopathy-Homing and Autophagy-Activating Nanoassembly for Specific Clearance of Pathogenic Tau in Alzheimer's Disease. Acs Nano. PMID 33683854 DOI: 10.1021/acsnano.0c10690   
2021 Takahashi RH, Yokotsuka M, Tobiume M, Sato Y, Hasegawa H, Nagao T, Gouras GK. Accumulation of cellular prion protein within β-amyloid oligomer plaques in aged human brains. Brain Pathology (Zurich, Switzerland). e12941. PMID 33624334 DOI: 10.1111/bpa.12941   
2021 Miranda A, Montiel E, Ulrich H, Paz C. Selective Secretase Targeting for Alzheimer's Disease Therapy. Journal of Alzheimer's Disease : Jad. PMID 33749645 DOI: 10.3233/JAD-201027   
2021 Ni J, Wu Z. Inflammation Spreading: Negative Spiral Linking Systemic Inflammatory Disorders and Alzheimer's Disease. Frontiers in Cellular Neuroscience. 15: 638686. PMID 33716675 DOI: 10.3389/fncel.2021.638686   
2021 Tosh JL, Rhymes ER, Mumford P, Whittaker HT, Pulford LJ, Noy SJ, Cleverley K, , Walker MC, Tybulewicz VLJ, Wykes RC, Fisher EMC, Wiseman FK. Genetic dissection of down syndrome-associated alterations in APP/amyloid-β biology using mouse models. Scientific Reports. 11: 5736. PMID 33707583 DOI: 10.1038/s41598-021-85062-3   
2021 Liu L, Xia G, Li P, Wang Y, Zhao Q. Sirt-1 Regulates Physiological Process and Exerts Protective Effects against Oxidative Stress. Biomed Research International. 2021: 5542545. PMID 33834065 DOI: 10.1155/2021/5542545   
2021 Qu Y, Wang W, Chen T, Yang Y, Zhang Y, Wang D. The neuroprotection of deproteinized calf blood extractives injection against Alzheimer's disease via regulation of Nrf-2 signaling. Aging. 13. PMID 33819182 DOI: 10.18632/aging.202776   
2021 Nackenoff AG, Hohman TJ, Neuner SM, Akers CS, Weitzel NC, Shostak A, Ferguson SM, Mobley B, Bennett DA, Schneider JA, Jefferson AL, Kaczorowski CC, Schrag MS. PLD3 is a neuronal lysosomal phospholipase D associated with β-amyloid plaques and cognitive function in Alzheimer's disease. Plos Genetics. 17: e1009406. PMID 33830999 DOI: 10.1371/journal.pgen.1009406   
2021 Kazim SF, Seo JH, Bianchi R, Larson CS, Sharma A, Wong RKS, Gorbachev KY, Pereira AC. Neuronal network excitability in Alzheimer's disease: The puzzle of similar versus divergent roles of amyloid β and tau. Eneuro. PMID 33741601 DOI: 10.1523/ENEURO.0418-20.2020   
2021 Singh YP, Rai H, Singh G, Singh GK, Mishra S, Kumar S, Srikrishna S, Modi G. A review on ferulic acid and analogs based scaffolds for the management of Alzheimer's disease. European Journal of Medicinal Chemistry. 215: 113278. PMID 33662757 DOI: 10.1016/j.ejmech.2021.113278   
2021 Xian-Hui D, Dong-Xue M, Tian-Ci Z, Xiao-Ping H, Li-Jun X, Ya-Lei L, Hao L, Wei-Juan G. The Effect of TCM-Induced HAMP on Key Enzymes in the Hydrolysis of AD Model Cells. Neurochemical Research. PMID 33683629 DOI: 10.1007/s11064-021-03235-y   
2021 Sato K, Ihara R, Suzuki K, Niimi Y, Toda T, Jimenez-Maggiora G, Langford O, Donohue MC, Raman R, Aisen PS, Sperling RA, Iwata A, Iwatsubo T. Predicting amyloid risk by machine learning algorithms based on the A4 screen data: Application to the Japanese Trial-Ready Cohort study. Alzheimer's & Dementia (New York, N. Y.). 7: e12135. PMID 33778148 DOI: 10.1002/trc2.12135   
2021 Cai T, Tomita T. Sequential conformational changes in transmembrane domains of presenilin 1 in Aβ42 downregulation. Journal of Biochemistry. PMID 33739423 DOI: 10.1093/jb/mvab033   
2021 Alakbarzade V, French JM, Howlett DR, Attems J, Francis PT, Stratton S, Clark CN, Pereira AC, Hainsworth AH. Cerebral amyloid angiopathy distribution in older people: A cautionary note. Alzheimer's & Dementia (New York, N. Y.). 7: e12145. PMID 33644295 DOI: 10.1002/trc2.12145