Erin H. Norris, Ph.D. - Related publications

Affiliations: 
2004 University of Pennsylvania, Philadelphia, PA, United States 
Area:
tau, dementia, neurodegeneration
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50 most relevant papers in past 60 days:
Year Citation  Score
2021 Kwon OC, Song JJ, Yang Y, Kim SH, Kim JY, Seok MJ, Hwang I, Yu JW, Karmacharya J, Maeng HJ, Kim J, Jho EH, Ko SY, Son H, Chang MY, et al. SGK1 inhibition in glia ameliorates pathologies and symptoms in Parkinson disease animal models. Embo Molecular Medicine. e13076. PMID 33646633 DOI: 10.15252/emmm.202013076   
2021 Maeda J, Minamihisamatsu T, Shimojo M, Zhou X, Ono M, Matsuba Y, Ji B, Ishii H, Ogawa M, Akatsu H, Kaneda D, Hashizume Y, Robinson JL, Lee VM, Saito T, et al. Distinct microglial response against Alzheimer's amyloid and tau pathologies characterized by P2Y12 receptor. Brain Communications. 3: fcab011. PMID 33644757 DOI: 10.1093/braincomms/fcab011   
2021 Tavassoly O, Del Cid Pellitero E, Larroquette F, Cai E, Thomas RA, Soubannier V, Luo W, Durcan TM, Fon EA. Pharmacological Inhibition of Brain EGFR Activation By a BBB-penetrating Inhibitor, AZD3759, Attenuates α-synuclein Pathology in a Mouse Model of α-Synuclein Propagation. Neurotherapeutics : the Journal of the American Society For Experimental Neurotherapeutics. PMID 33713002 DOI: 10.1007/s13311-021-01017-6   
2021 Reyes JF, Ekmark-Léwen S, Perdiki M, Klingstedt T, Hoffmann A, Wiechec E, Nilsson P, Nilsson KPR, Alafuzoff I, Ingelsson M, Hallbeck M. Accumulation of alpha-synuclein within the liver, potential role in the clearance of brain pathology associated with Parkinson's disease. Acta Neuropathologica Communications. 9: 46. PMID 33743820 DOI: 10.1186/s40478-021-01136-3   
2021 Bourgognon JM, Spiers JG, Robinson SW, Scheiblich H, Glynn P, Ortori C, Bradley SJ, Tobin AB, Steinert JR. Inhibition of neuroinflammatory nitric oxide signaling suppresses glycation and prevents neuronal dysfunction in mouse prion disease. Proceedings of the National Academy of Sciences of the United States of America. 118. PMID 33653950 DOI: 10.1073/pnas.2009579118   
2021 Roshanbin S, Aniszewska A, Gumucio A, Masliah E, Erlandsson A, Bergström J, Ingelsson M, Ekmark-Lewén S. Age-related increase of alpha-synuclein oligomers is associated with motor disturbances in L61 transgenic mice. Neurobiology of Aging. 101: 207-220. PMID 33639338 DOI: 10.1016/j.neurobiolaging.2021.01.010   
2021 Jang M, Choi SH, Choi JH, Oh J, Lee RM, Lee NE, Cho YJ, Rhim H, Kim HC, Cho IH, Nah SY. Ginseng gintonin attenuates the disruptions of brain microvascular permeability and microvascular endothelium junctional proteins in an APPswe/PSEN-1 double-transgenic mouse model of Αlzheimer's disease. Experimental and Therapeutic Medicine. 21: 310. PMID 33717253 DOI: 10.3892/etm.2021.9741   
2021 Akter R, Rahman MH, Behl T, Chowdhury MAR, Manirujjaman M, Bulbul IJ, Elshenaw SE, Tit DM, Bungau S. Prospective Role of Polyphenolic Compounds in the Treatment of Neurodegenerative Diseases. Cns & Neurological Disorders Drug Targets. PMID 33602109 DOI: 10.2174/1871527320666210218084444   
2021 Thompson TB, Meisl G, Knowles TPJ, Goriely A. The role of clearance mechanisms in the kinetics of pathological protein aggregation involved in neurodegenerative diseases. The Journal of Chemical Physics. 154: 125101. PMID 33810689 DOI: 10.1063/5.0031650   
2021 Qu Y, Wang W, Chen T, Yang Y, Zhang Y, Wang D. The neuroprotection of deproteinized calf blood extractives injection against Alzheimer's disease via regulation of Nrf-2 signaling. Aging. 13. PMID 33819182 DOI: 10.18632/aging.202776   
2021 Sharma S. Role of Extracellular vesicles in Alzheimer's disease: Current Advances. Current Molecular Medicine. PMID 33823777 DOI: 10.2174/1566524021666210406121807   
2021 Criado-Marrero M, Gebru NT, Blazier DM, Gould LA, Baker JD, Beaulieu-Abdelahad D, Blair LJ. Hsp90 co-chaperones, FKBP52 and Aha1, promote tau pathogenesis in aged wild-type mice. Acta Neuropathologica Communications. 9: 65. PMID 33832539 DOI: 10.1186/s40478-021-01159-w   
2021 Ulm BS, Borchelt DR, Moore BD. Remodeling Alzheimer-amyloidosis models by seeding. Molecular Neurodegeneration. 16: 8. PMID 33588898 DOI: 10.1186/s13024-021-00429-4   
2021 Ajoolabady A, Aslkhodapasandhokmabad H, Henninger N, Demillard LJ, Nikanfar M, Nourazarian A, Ren J. Targeting Autophagy in Neurodegenerative Diseases: from Molecular Mechanisms to Clinical Therapeutics. Clinical and Experimental Pharmacology & Physiology. PMID 33752254 DOI: 10.1111/1440-1681.13500   
2021 Meisl G, Kurt T, Condado-Morales I, Bett C, Sorce S, Nuvolone M, Michaels TCT, Heinzer D, Avar M, Cohen SIA, Hornemann S, Aguzzi A, Dobson CM, Sigurdson CJ, Knowles TPJ. Scaling analysis reveals the mechanism and rates of prion replication in vivo. Nature Structural & Molecular Biology. PMID 33767451 DOI: 10.1038/s41594-021-00565-x   
2021 Wang K, Wang L, Chen L, Peng C, Luo B, Mo J, Chen W. Intranasal administration of dauricine loaded on graphene oxide: multi-target therapy for Alzheimer's disease. Drug Delivery. 28: 580-593. PMID 33729067 DOI: 10.1080/10717544.2021.1895909   
2021 Zheng X, Lin W, Jiang Y, Lu K, Wei W, Huo Q, Cui S, Yang X, Li M, Xu N, Tang C, Song JX. Electroacupuncture ameliorates beta-amyloid pathology and cognitive impairment in Alzheimer disease via a novel mechanism involving activation of TFEB (transcription factor EB). Autophagy. 1-15. PMID 33622188 DOI: 10.1080/15548627.2021.1886720   
2021 Lau JKY, Tian M, Shen Y, Lau SF, Fu WY, Fu AKY, Ip NY. Melanocortin receptor activation alleviates amyloid pathology and glial reactivity in an Alzheimer's disease transgenic mouse model. Scientific Reports. 11: 4359. PMID 33623128 DOI: 10.1038/s41598-021-83932-4   
2021 Gu H, Yang X, Mao X, Xu E, Qi C, Wang H, Brahmachari S, York B, Sriparna M, Li A, Chang M, Patel P, Dawson VL, Dawson TM. Lymphocyte Activation Gene 3 (Lag3) Contributes to α-Synucleinopathy in α-Synuclein Transgenic Mice. Frontiers in Cellular Neuroscience. 15: 656426. PMID 33776654 DOI: 10.3389/fncel.2021.656426   
2021 Khan A, Das S, Sergi C. Therapeutic Potential of Neu1 in Alzheimer's Disease Via the Immune System. American Journal of Alzheimer's Disease and Other Dementias. 36: 1533317521996147. PMID 33719595 DOI: 10.1177/1533317521996147   
2021 Cash MK, Rockwood K, Fisk JD, Darvesh S. Clinicopathological correlations and cholinesterase expression in early-onset familial Alzheimer's disease with the presenilin 1 mutation, Leu235Pro. Neurobiology of Aging. 103: 31-41. PMID 33789210 DOI: 10.1016/j.neurobiolaging.2021.02.025   
2021 Clayton K, Delpech JC, Herron S, Iwahara N, Ericsson M, Saito T, Saido TC, Ikezu S, Ikezu T. Plaque associated microglia hyper-secrete extracellular vesicles and accelerate tau propagation in a humanized APP mouse model. Molecular Neurodegeneration. 16: 18. PMID 33752701 DOI: 10.1186/s13024-021-00440-9   
2021 Soto-Rojas LO, Pacheco-Herrero M, Martínez-Gómez PA, Campa-Córdoba BB, Apátiga-Pérez R, Villegas-Rojas MM, Harrington CR, de la Cruz F, Garcés-Ramírez L, Luna-Muñoz J. The Neurovascular Unit Dysfunction in Alzheimer's Disease. International Journal of Molecular Sciences. 22. PMID 33670754 DOI: 10.3390/ijms22042022   
2021 Jin JW, Fan X, Del Cid-Pellitero E, Liu XX, Zhou L, Dai C, Gibbs E, He W, Li H, Wu X, Hill A, Leavitt BR, Cashman N, Liu L, Lu J, et al. Development of an α-synuclein knockdown peptide and evaluation of its efficacy in Parkinson's disease models. Communications Biology. 4: 232. PMID 33608634 DOI: 10.1038/s42003-021-01746-6   
2021 Jiang H, Niu F, Zheng Y, Xu Y. CART mitigates oxidative stress and DNA damage in memory deficits of APP/PS1 mice via upregulating β‑amyloid metabolism‑associated enzymes. Molecular Medicine Reports. 23: 1-12. PMID 33604684 DOI: 10.3892/mmr.2021.11919   
2021 Zimmer JA, Shcherbinin S, Devous MD, Bragg SM, Selzler KJ, Wessels AM, Shering C, Mullen J, Landry J, Andersen SW, Downing AM, Fleisher AS, Svaldi DO, Sims JR. Lanabecestat: Neuroimaging results in early symptomatic Alzheimer's disease. Alzheimer's & Dementia (New York, N. Y.). 7: e12123. PMID 33614894 DOI: 10.1002/trc2.12123   
2021 Fiolek TJ, Keel KL, Tepe JJ. Fluspirilene Analogs Activate the 20S Proteasome and Overcome Proteasome Impairment by Intrinsically Disordered Protein Oligomers. Acs Chemical Neuroscience. PMID 33788542 DOI: 10.1021/acschemneuro.1c00099   
2021 Stojkovska I, Mazzulli JR. Detection of pathological alpha-synuclein aggregates in human iPSC-derived neurons and tissue. Star Protocols. 2: 100372. PMID 33733241 DOI: 10.1016/j.xpro.2021.100372   
2021 Rivers-Auty J, Tapia VS, White CS, Daniels MJ, Drinkall S, Kennedy PT, Spence HG, Yu S, Green JP, Hoyle C, Cook J, Bradley A, Mather AE, Peters R, Tzeng TC, et al. Zinc status alters Alzheimer's disease progression through NLRP3-dependent inflammation. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 33597269 DOI: 10.1523/JNEUROSCI.1980-20.2020   
2021 Bretland KA, Lin L, Bretland KM, Smith MA, Fleming SM, Dengler-Crish CM. Irisin treatment lowers levels of phosphorylated tau in the hippocampus of pre-symptomatic female but not male htau mice. Neuropathology and Applied Neurobiology. PMID 33768561 DOI: 10.1111/nan.12711   
2021 Shafiq K, Sanghai N, Guo Y, Kong J. Implication of post-translationally modified SOD1 in pathological aging. Geroscience. PMID 33608813 DOI: 10.1007/s11357-021-00332-2   
2021 Holbrook JA, Jarosz-Griffiths HH, Caseley E, Lara-Reyna S, Poulter JA, Williams-Gray CH, Peckham D, McDermott MF. Neurodegenerative Disease and the NLRP3 Inflammasome. Frontiers in Pharmacology. 12: 643254. PMID 33776778 DOI: 10.3389/fphar.2021.643254   
2021 Wu T, Chen L, Zhou L, Xu J, Guo K. Platelets transport β-amyloid from the peripheral blood into the brain by destroying the blood-brain barrier to accelerate the process of Alzheimer's disease in mouse models. Aging. 13. PMID 33668038 DOI: 10.18632/aging.202662   
2021 Pan Q, Ban Y, Khan S. Antioxidant activity of calycosin against α-synuclein amyloid fibrils-induced oxidative stress in neural-like cells as a model of preventive care studies in Parkinson's disease. International Journal of Biological Macromolecules. PMID 33798579 DOI: 10.1016/j.ijbiomac.2021.03.186   
2021 Scheffer S, Hermkens DMA, van der Weerd L, de Vries HE, Daemen MJAP. Vascular Hypothesis of Alzheimer Disease: Topical Review of Mouse Models. Arteriosclerosis, Thrombosis, and Vascular Biology. ATVBAHA120311911. PMID 33626911 DOI: 10.1161/ATVBAHA.120.311911   
2021 Elmazoglu Z, Galván-Arzate S, Aschner M, Rangel-López E, Bayraktar O, Santamaría A, Karasu Ç. Redox-active phytoconstituents ameliorate cell damage and inflammation in rat hippocampal neurons exposed to hyperglycemia+Aβ peptide. Neurochemistry International. 145: 104993. PMID 33610590 DOI: 10.1016/j.neuint.2021.104993   
2021 Singh YP, Rai H, Singh G, Singh GK, Mishra S, Kumar S, Srikrishna S, Modi G. A review on ferulic acid and analogs based scaffolds for the management of Alzheimer's disease. European Journal of Medicinal Chemistry. 215: 113278. PMID 33662757 DOI: 10.1016/j.ejmech.2021.113278   
2021 Kubota S, Doi H, Koyano S, Tanaka K, Komiya H, Katsumoto A, Ikeda S, Hashiguchi S, Nakamura H, Fukai R, Takahashi K, Kunii M, Tada M, Takeuchi H, Tanaka F. SGTA associates with intracellular aggregates in neurodegenerative diseases. Molecular Brain. 14: 59. PMID 33757575 DOI: 10.1186/s13041-021-00770-1   
2021 Wang YY, Huang ZT, Yuan MH, Jing F, Cai RL, Zou Q, Pu YS, Wang SY, Chen F, Yi WM, Zhang HJ, Cai ZY. Role of Hypoxia Inducible Factor-1α in Alzheimer's Disease. Journal of Alzheimer's Disease : Jad. PMID 33612545 DOI: 10.3233/JAD-201448   
2021 Tian DY, Cheng Y, Zhuang ZQ, He CY, Pan QG, Tang MZ, Hu XL, Shen YY, Wang YR, Chen SH, Sun HL, Sun PY, Yu ZY, Fan DY, Bu XL, et al. Physiological clearance of amyloid-beta by the kidney and its therapeutic potential for Alzheimer's disease. Molecular Psychiatry. PMID 33828237 DOI: 10.1038/s41380-021-01073-6   
2021 Sokratian A, Ziaee J, Kelly K, Chang A, Bryant N, Wang S, Xu E, Li JY, Wang SH, Ervin J, Swain SM, Liddle RA, West AB. Heterogeneity in α-synuclein fibril activity correlates to disease phenotypes in Lewy body dementia. Acta Neuropathologica. PMID 33641009 DOI: 10.1007/s00401-021-02288-1   
2021 Ju IG, Huh E, Kim N, Lee S, Choi JG, Hong J, Oh MS. Artemisiae Iwayomogii Herba inhibits lipopolysaccharide-induced neuroinflammation by regulating NF-κB and MAPK signaling pathways. Phytomedicine : International Journal of Phytotherapy and Phytopharmacology. 84: 153501. PMID 33626425 DOI: 10.1016/j.phymed.2021.153501   
2021 Thammisetty SS, Renaud L, Picher-Martel V, Weng YC, Calon F, Saikali S, Julien JP, Kriz J. Targeting TDP-43 Pathology Alleviates Cognitive and Motor Deficits Caused by Chronic Cerebral Hypoperfusion. Neurotherapeutics : the Journal of the American Society For Experimental Neurotherapeutics. PMID 33786804 DOI: 10.1007/s13311-021-01015-8   
2021 Navas Guimaraes ME, Lopez-Blanco R, Correa J, Fernandez-Villamarin M, Bistué MB, Martino-Adami P, Morelli L, Kumar V, Wempe MF, Cuello AC, Fernandez-Megia E, Bruno MA. Liver X Receptor Activation with an Intranasal Polymer Therapeutic Prevents Cognitive Decline without Altering Lipid Levels. Acs Nano. PMID 33666411 DOI: 10.1021/acsnano.0c09159   
2021 Nam Y, Moon GJ, Kim SR. Therapeutic Potential of AAV1-Rheb(S16H) Transduction against Neurodegenerative Diseases. International Journal of Molecular Sciences. 22. PMID 33802760 DOI: 10.3390/ijms22063064   
2021 Ni J, Wu Z. Inflammation Spreading: Negative Spiral Linking Systemic Inflammatory Disorders and Alzheimer's Disease. Frontiers in Cellular Neuroscience. 15: 638686. PMID 33716675 DOI: 10.3389/fncel.2021.638686   
2021 Brás IC, Outeiro TF. Alpha-Synuclein: Mechanisms of Release and Pathology Progression in Synucleinopathies. Cells. 10. PMID 33673034 DOI: 10.3390/cells10020375   
2021 Prasanna P, Upadhyay A. Flavonoid-Based Nanomedicines in Alzheimer's Disease Therapeutics: Promises Made, a Long Way To Go. Acs Pharmacology & Translational Science. 4: 74-95. PMID 33615162 DOI: 10.1021/acsptsci.0c00224   
2021 Shin EJ, Park JW. Nanoaggregates Derived from Amyloid-beta and Alpha-synuclein Characterized by Sequential Quadruple Force Mapping. Nano Letters. PMID 33845574 DOI: 10.1021/acs.nanolett.1c00058   
2021 Nahass GR, Sun Y, Xu Y, Batchelor M, Reilly M, Benilova I, Kedia N, Spehar K, Sobott F, Sessions RB, Caughey BW, Radford SE, Jat P, Collinge J, Bieschke J. Brazilin Removes Toxic alpha-Synuclein and Seeding Competent Assemblies from Parkinson Brain by Altering Conformational Equilibrium. Journal of Molecular Biology. 166878. PMID 33610557 DOI: 10.1016/j.jmb.2021.166878