Deepa V. Dabir, Ph.D. - Related publications

Affiliations: 
2006 University of Pennsylvania, Philadelphia, PA, United States 
Area:
tau, dementia, neurodegeneration
NOTE: We are testing a new system for identifying relevant work based on semantic analysis that identifies similarities between recently published papers and the current author's publications. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches.
50 most relevant papers in past 60 days:
Year Citation  Score
2021 Song L, Wells EA, Robinson AS. Critical Molecular and Cellular Contributors to Tau Pathology. Biomedicines. 9. PMID 33672982 DOI: 10.3390/biomedicines9020190   
2021 Li L, Shi R, Gu J, Tung YC, Zhou Y, Zhou D, Wu R, Chu D, Jin N, Deng K, Xu J, Gong CX, Iqbal K, Liu F. Alzheimer's disease brain contains tau fractions with differential prion-like activities. Acta Neuropathologica Communications. 9: 28. PMID 33597014 DOI: 10.1186/s40478-021-01127-4   
2021 Tarutani A, Miyata H, Nonaka T, Hasegawa K, Yoshida M, Saito Y, Murayama S, Robinson AC, Mann DMA, Tomita T, Hasegawa M. Human tauopathy-derived tau strains determine the substrates recruited for templated amplification. Brain : a Journal of Neurology. PMID 33693528 DOI: 10.1093/brain/awab091   
2021 Carlomagno Y, Manne S, DeTure M, Prudencio M, Zhang YJ, Hanna Al-Shaikh R, Dunmore JA, Daughrity LM, Song Y, Castanedes-Casey M, Lewis-Tuffin LJ, Nicholson KA, Wszolek ZK, Dickson DW, Fitzpatrick AWP, et al. The AD tau core spontaneously self-assembles and recruits full-length tau to filaments. Cell Reports. 34: 108843. PMID 33730588 DOI: 10.1016/j.celrep.2021.108843   
2021 Soares AC, Ferreira A, Mariën J, Delay C, Lee E, Trojanowski JQ, Moechars D, Annaert W, De Muynck L. PIKfyve activity is required for lysosomal trafficking of tau aggregates and tau seeding. The Journal of Biological Chemistry. 100636. PMID 33831417 DOI: 10.1016/j.jbc.2021.100636   
2021 Clayton K, Delpech JC, Herron S, Iwahara N, Ericsson M, Saito T, Saido TC, Ikezu S, Ikezu T. Plaque associated microglia hyper-secrete extracellular vesicles and accelerate tau propagation in a humanized APP mouse model. Molecular Neurodegeneration. 16: 18. PMID 33752701 DOI: 10.1186/s13024-021-00440-9   
2021 Darling AL, Dahrendorff J, Creodore SG, Dickey CA, Blair LJ, Uversky VN. Small heat shock protein 22kDa can modulate the aggregation and liquid-liquid phase separation behavior of Tau. Protein Science : a Publication of the Protein Society. PMID 33686711 DOI: 10.1002/pro.4060   
2021 Vasconcelos IC, Campos RM, Schwaemmle HM, Masson AP, Ferrari GD, Alberici LC, Faça VM, Garcia-Cairasco N, Sebollela A. A freeze-and-thaw induced-fragment of the microtubule-associated protein Tau in rat brain extracts: implications for the biochemical assessment of neurotoxicity. Bioscience Reports. PMID 33629708 DOI: 10.1042/BSR20203980   
2021 McMurray L, Macdonald JA, Ramakrishnan NK, Zhao Y, Williamson DW, Tietz O, Zhou X, Kealey S, Fagan SG, Smolek T, Cubinkova V, Žilka N, Spillantini MG, Tolkovsky AM, Goedert M, et al. Synthesis and Assessment of Novel Probes for Imaging Tau Pathology in Transgenic Mouse and Rat Models. Acs Chemical Neuroscience. PMID 33689290 DOI: 10.1021/acschemneuro.0c00790   
2021 Pan D, Gu JH, Zhang J, Hu Y, Liu F, Iqbal K, Cekic N, Vocadlo DJ, Dai CL, Gong CX. Thiamme2-G, A Novel O-GlcNAcase Inhibitor, Reduces Tau Hyperphosphorylation and Rescues Cognitive Impairment in Mice. Journal of Alzheimer's Disease : Jad. PMID 33814439 DOI: 10.3233/JAD-201450   
2021 Ungerleider K, Beck J, Lissa D, Turnquist C, Horikawa I, Harris BT, Harris CC. Astrocyte senescence and SASP in neurodegeneration: tau joins the loop. Cell Cycle (Georgetown, Tex.). 1-13. PMID 33818291 DOI: 10.1080/15384101.2021.1909260   
2021 Lathuiliere A, Hyman BT. Quantitative Methods for the Detection of Tau Seeding Activity in Human Biofluids. Frontiers in Neuroscience. 15: 654176. PMID 33828458 DOI: 10.3389/fnins.2021.654176   
2021 Wegmann S, DeVos SL, Zeitler B, Marlen K, Bennett RE, Perez-Rando M, MacKenzie D, Yu Q, Commins C, Bannon RN, Corjuc BT, Chase A, Diez L, Nguyen HB, Hinkley S, et al. Persistent repression of tau in the brain using engineered zinc finger protein transcription factors. Science Advances. 7. PMID 33741591 DOI: 10.1126/sciadv.abe1611   
2021 Mueller RL, Combs B, Alhadidy MM, Brady ST, Morfini GA, Kanaan NM. Tau: A Signaling Hub Protein. Frontiers in Molecular Neuroscience. 14: 647054. PMID 33815057 DOI: 10.3389/fnmol.2021.647054   
2021 Wang C, Xiong M, Gratuze M, Bao X, Shi Y, Andhey PS, Manis M, Schroeder C, Yin Z, Madore C, Butovsky O, Artyomov M, Ulrich JD, Holtzman DM. Selective removal of astrocytic APOE4 strongly protects against tau-mediated neurodegeneration and decreases synaptic phagocytosis by microglia. Neuron. PMID 33831349 DOI: 10.1016/j.neuron.2021.03.024   
2021 Wang C, Xiong M, Gratuze M, Bao X, Shi Y, Andhey PS, Manis M, Schroeder C, Yin Z, Madore C, Butovsky O, Artyomov M, Ulrich JD, Holtzman DM. Selective removal of astrocytic APOE4 strongly protects against tau-mediated neurodegeneration and decreases synaptic phagocytosis by microglia. Neuron. PMID 33831349 DOI: 10.1016/j.neuron.2021.03.024   
2021 Xiao S, Lu Y, Wu Q, Yang J, Chen J, Zhong S, Eliezer D, Tan Q, Wu C. Fisetin inhibits tau aggregation by interacting with the protein and preventing the formation of β-strands. International Journal of Biological Macromolecules. PMID 33662414 DOI: 10.1016/j.ijbiomac.2021.02.210   
2021 Chang CW, Shao E, Mucke L. Tau: Enabler of diverse brain disorders and target of rapidly evolving therapeutic strategies. Science (New York, N.Y.). 371. PMID 33632820 DOI: 10.1126/science.abb8255   
2021 Miller LVC, Mukadam AS, Durrant CS, Vaysburd MJ, Katsinelos T, Tuck BJ, Sanford S, Sheppard O, Knox C, Cheng S, James LC, Coleman MP, McEwan WA. Tau assemblies do not behave like independently acting prion-like particles in mouse neural tissue. Acta Neuropathologica Communications. 9: 41. PMID 33712082 DOI: 10.1186/s40478-021-01141-6   
2021 Criado-Marrero M, Gebru NT, Blazier DM, Gould LA, Baker JD, Beaulieu-Abdelahad D, Blair LJ. Hsp90 co-chaperones, FKBP52 and Aha1, promote tau pathogenesis in aged wild-type mice. Acta Neuropathologica Communications. 9: 65. PMID 33832539 DOI: 10.1186/s40478-021-01159-w   
2021 Khodarahmi R, Akbari V, Mohammadi S, Farshadnia T, Rahimabadi MM, Goicoechea HC, Jalalvand AR. Chemometric modeling of the electrochemical data to investigate proline cis/trans isomeration effect on aggregation of Tau protein. Protein Expression and Purification. 182: 105858. PMID 33639278 DOI: 10.1016/j.pep.2021.105858   
2021 Gelpi E, Aldecoa I, Lopez-Villegas D, Abellan-Vidal MT, Mercadel-Fañanas P, Fortea J, Roser R, Estrella M, Gomez-Anson B, Molina-Porcel L, Ximelis T, Borrego S, Antonell A, Rovelet-Lecrux A, Klotz S, et al. Atypical astroglial pTDP-43 pathology in astroglial predominant tauopathy. Neuropathology and Applied Neurobiology. PMID 33730418 DOI: 10.1111/nan.12707   
2021 Martellucci S, Clementi L, Sabetta S, Muzi P, Mattei V, Bologna M, Angelucci A. Tau oligomers accumulation sensitizes prostate cancer cells to docetaxel treatment. Journal of Cancer Research and Clinical Oncology. PMID 33811272 DOI: 10.1007/s00432-021-03598-3   
2021 Bajracharya R, Brici D, Bodea LG, Janowicz PW, Götz J, Nisbet RM. Tau antibody isotype induces differential effects following passive immunisation of tau transgenic mice. Acta Neuropathologica Communications. 9: 42. PMID 33712083 DOI: 10.1186/s40478-021-01147-0   
2021 Adams JN, Maass A, Berron D, Harrison TM, Baker SL, Thomas WP, Stanfill M, Jagust WJ. Reduced repetition suppression in aging is driven by tau-related hyperactivity in medial temporal lobe. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 33731446 DOI: 10.1523/JNEUROSCI.2504-20.2021   
2021 Ding XL, Tuo QZ, Lei P. An Introduction to Ultrasensitive Assays for Plasma Tau Detection. Journal of Alzheimer's Disease : Jad. PMID 33682718 DOI: 10.3233/JAD-201499   
2021 Shin J, Yang SH, Du YE, Park K, Kim D, Shin D, Kim J, Kim SH, Kim YK, Shin J, Oh DC, Kim Y. Borrelidin from Saltern-Derived Halophilic sp. Dissociates Amyloid- and Tau Fibrils. Journal of Alzheimer's Disease Reports. 5: 7-13. PMID 33681712 DOI: 10.3233/ADR-200247   
2021 Ding X, Zhang S, Jiang L, Wang L, Li T, Lei P. Ultrasensitive assays for detection of plasma tau and phosphorylated tau 181 in Alzheimer's disease: a systematic review and meta-analysis. Translational Neurodegeneration. 10: 10. PMID 33712071 DOI: 10.1186/s40035-021-00234-5   
2021 Ash PEA, Lei S, Shattuck J, Boudeau S, Carlomagno Y, Medalla M, Mashimo BL, Socorro G, Al-Mohanna LFA, Jiang L, Öztürk MM, Knobel M, Ivanov P, Petrucelli L, Wegmann S, et al. TIA1 potentiates tau phase separation and promotes generation of toxic oligomeric tau. Proceedings of the National Academy of Sciences of the United States of America. 118. PMID 33619090 DOI: 10.1073/pnas.2014188118   
2021 Suire CN, Leissring MA. Cathepsin D: A Candidate Link between Amyloid β-protein and Tauopathy in Alzheimer Disease. Journal of Experimental Neurology. 2: 10-15. PMID 33665647   
2021 Latina V, Giacovazzo G, Cordella F, Balzamino BO, Micera A, Varano M, Marchetti C, Malerba F, Florio R, Ercole BB, La Regina F, Atlante A, Coccurello R, Di Angelantonio S, Calissano P, et al. Systemic delivery of a specific antibody targeting the pathological N-terminal truncated tau peptide reduces retinal degeneration in a mouse model of Alzheimer's Disease. Acta Neuropathologica Communications. 9: 38. PMID 33750467 DOI: 10.1186/s40478-021-01138-1   
2021 Leonard C, Phillips C, McCarty J. Insight Into Seeded Tau Fibril Growth From Molecular Dynamics Simulation of the Alzheimer's Disease Protofibril Core. Frontiers in Molecular Biosciences. 8: 624302. PMID 33816551 DOI: 10.3389/fmolb.2021.624302   
2021 Xia Y, Nasif L, Giasson BI. Pathogenic MAPT mutations Q336H and Q336R have isoform-dependent differences in aggregation propensity and microtubule dysfunction. Journal of Neurochemistry. PMID 33772783 DOI: 10.1111/jnc.15358   
2021 Moloney CM, Lowe VJ, Murray ME. Visualization of neurofibrillary tangle maturity in Alzheimer's disease: A clinicopathologic perspective for biomarker research. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 33797838 DOI: 10.1002/alz.12321   
2021 Peyron PA, Hirtz C, Baccino E, Ginestet N, Tiers L, Martinez AY, Lehmann S, Delaby C. Tau protein in cerebrospinal fluid: a novel biomarker of the time of death? International Journal of Legal Medicine. PMID 33740116 DOI: 10.1007/s00414-021-02558-3   
2021 Wisessaowapak C, Visitnonthachai D, Watcharasit P, Satayavivad J. Prolonged arsenic exposure increases tau phosphorylation in differentiated SH-SY5Y cells: The contribution of GSK3 and ERK1/2. Environmental Toxicology and Pharmacology. 84: 103626. PMID 33621689 DOI: 10.1016/j.etap.2021.103626   
2021 Yap SY, Frias B, Wren MC, Schöll M, Fox NC, Årstad E, Lashley T, Sander K. Discriminatory ability of next-generation tau PET tracers for Alzheimer's disease. Brain : a Journal of Neurology. PMID 33742656 DOI: 10.1093/brain/awab120   
2021 Sun H, Zhong Y, Zhu X, Liao H, Lee J, Chen Y, Ma L, Ren J, Zhao M, Tu M, Li F, Zhang H, Tian M, Ling D. A Tauopathy-Homing and Autophagy-Activating Nanoassembly for Specific Clearance of Pathogenic Tau in Alzheimer's Disease. Acs Nano. PMID 33683854 DOI: 10.1021/acsnano.0c10690   
2021 Gerrits E, Brouwer N, Kooistra SM, Woodbury ME, Vermeiren Y, Lambourne M, Mulder J, Kummer M, Möller T, Biber K, Dunnen WFAD, De Deyn PP, Eggen BJL, Boddeke EWGM. Distinct amyloid-β and tau-associated microglia profiles in Alzheimer's disease. Acta Neuropathologica. PMID 33609158 DOI: 10.1007/s00401-021-02263-w   
2021 Friedrich MG, Skora A, Hancock SE, Mitchell TW, Else PL, Truscott RJW. Tau Is Truncated in Five Regions of the Normal Adult Human Brain. International Journal of Molecular Sciences. 22. PMID 33805376 DOI: 10.3390/ijms22073521   
2021 Rübsamen N, Maceski A, Leppert D, Benkert P, Kuhle J, Wiendl H, Peters A, Karch A, Berger K. Serum neurofilament light and tau as prognostic markers for all-cause mortality in the elderly general population-an analysis from the MEMO study. Bmc Medicine. 19: 38. PMID 33583409 DOI: 10.1186/s12916-021-01915-8   
2021 Bachstetter AD, Garrett FG, Jicha GA, Nelson PT. Space-occupying brain lesions, trauma-related tau astrogliopathy, and ARTAG: a report of two cases and a literature review. Acta Neuropathologica Communications. 9: 49. PMID 33757579 DOI: 10.1186/s40478-021-01152-3   
2021 Xu M, Lu M, Zhang W, Jin Q, Chen Y. Simultaneous Detection of Six Isoforms of Tau Protein in Human Cerebrospinal Fluid by Multidimensional Mass Spectrometry-Based Targeted Proteomics. Journal of Proteome Research. PMID 33843226 DOI: 10.1021/acs.jproteome.0c00826   
2021 Medina L, González-Lizárraga F, Dominguez-Meijide A, Ploper D, Parrales V, Sequeira S, Cima-Omori MS, Zweckstetter M, Del Bel E, Michel PP, Outeiro TF, Raisman-Vozari R, Chehín R, Socias SB. Doxycycline Interferes With Tau Aggregation and Reduces Its Neuronal Toxicity. Frontiers in Aging Neuroscience. 13: 635760. PMID 33828477 DOI: 10.3389/fnagi.2021.635760   
2021 Prikas E, Ahel H, Stefanoska K, Asih PR, Volkerling A, Ittner LM, Ittner A. Interaction between the guanylate kinase domain of PSD-95 and the proline-rich region and microtubule binding repeats 2 and 3 of tau. Biochemistry and Cell Biology = Biochimie Et Biologie Cellulaire. PMID 33794133 DOI: 10.1139/bcb-2020-0604   
2021 Noël A, Foveau B, LeBlanc AC. Caspase-6-cleaved Tau fails to induce Tau hyperphosphorylation and aggregation, neurodegeneration, glial inflammation, and cognitive deficits. Cell Death & Disease. 12: 227. PMID 33649324 DOI: 10.1038/s41419-021-03506-0   
2021 Maeda J, Minamihisamatsu T, Shimojo M, Zhou X, Ono M, Matsuba Y, Ji B, Ishii H, Ogawa M, Akatsu H, Kaneda D, Hashizume Y, Robinson JL, Lee VM, Saito T, et al. Distinct microglial response against Alzheimer's amyloid and tau pathologies characterized by P2Y12 receptor. Brain Communications. 3: fcab011. PMID 33644757 DOI: 10.1093/braincomms/fcab011   
2021 Lee SH, Meilandt WJ, Xie L, Gandham VD, Ngu H, Barck KH, Rezzonico MG, Imperio J, Lalehzadeh G, Huntley MA, Stark KL, Foreman O, Carano RAD, Friedman BA, Sheng M, et al. Trem2 restrains the enhancement of tau accumulation and neurodegeneration by β-amyloid pathology. Neuron. PMID 33675684 DOI: 10.1016/j.neuron.2021.02.010   
2021 Huang P, Xu M, He YX. MicroRNA-146a regulates the expression of the Aβ1-42 protein in Alzheimer's disease. European Review For Medical and Pharmacological Sciences. 25: 2003-2012. PMID 33660812 DOI: 10.26355/eurrev_202102_25102   
2021 Kim S, Kim K, Nho K, Myung W, Won HH. Shared Genetic Background Between Cerebrospinal Fluid Biomarkers and Risk for Alzheimer's Disease: A Two-Sample Mendelian Randomization Study. Journal of Alzheimer's Disease : Jad. PMID 33646147 DOI: 10.3233/JAD-200671