Diana W. Shineman, Ph.D. - Related publications

Affiliations: 
2008 University of Pennsylvania, Philadelphia, PA, United States 
Area:
tau, dementia, neurodegeneration
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50 most relevant papers in past 60 days:
Year Citation  Score
2021 Zimmer JA, Shcherbinin S, Devous MD, Bragg SM, Selzler KJ, Wessels AM, Shering C, Mullen J, Landry J, Andersen SW, Downing AM, Fleisher AS, Svaldi DO, Sims JR. Lanabecestat: Neuroimaging results in early symptomatic Alzheimer's disease. Alzheimer's & Dementia (New York, N. Y.). 7: e12123. PMID 33614894 DOI: 10.1002/trc2.12123   
2021 Zheng X, Lin W, Jiang Y, Lu K, Wei W, Huo Q, Cui S, Yang X, Li M, Xu N, Tang C, Song JX. Electroacupuncture ameliorates beta-amyloid pathology and cognitive impairment in Alzheimer disease via a novel mechanism involving activation of TFEB (transcription factor EB). Autophagy. 1-15. PMID 33622188 DOI: 10.1080/15548627.2021.1886720   
2021 Lee SB, Park A, Ma CT, Kim YH, Yang HO. 3'-O-Acetyl-24-Epi-7,8-Didehydrocimigenol-3-O-β-D-Xylopryranoside Decreases Amyloid Beta Production in Amyloid Precursor Protein-Transfected HeLa Cells. Biomolecules & Therapeutics. PMID 33619237 DOI: 10.4062/biomolther.2020.195   
2021 Qu Y, Wang W, Chen T, Yang Y, Zhang Y, Wang D. The neuroprotection of deproteinized calf blood extractives injection against Alzheimer's disease via regulation of Nrf-2 signaling. Aging. 13. PMID 33819182 DOI: 10.18632/aging.202776   
2021 Wijesekara N, Gonçalves RA, Ahrens R, Ha K, De Felice FG, Fraser PE. Combination of human tau and islet amyloid polypeptide exacerbates metabolic dysfunction in transgenic mice. The Journal of Pathology. PMID 33797777 DOI: 10.1002/path.5674   
2021 Jang M, Choi SH, Choi JH, Oh J, Lee RM, Lee NE, Cho YJ, Rhim H, Kim HC, Cho IH, Nah SY. Ginseng gintonin attenuates the disruptions of brain microvascular permeability and microvascular endothelium junctional proteins in an APPswe/PSEN-1 double-transgenic mouse model of Αlzheimer's disease. Experimental and Therapeutic Medicine. 21: 310. PMID 33717253 DOI: 10.3892/etm.2021.9741   
2021 Brown A, Török M. Functional amyloids in the human body. Bioorganic & Medicinal Chemistry Letters. 127914. PMID 33691165 DOI: 10.1016/j.bmcl.2021.127914   
2021 Tosh JL, Rhymes ER, Mumford P, Whittaker HT, Pulford LJ, Noy SJ, Cleverley K, , Walker MC, Tybulewicz VLJ, Wykes RC, Fisher EMC, Wiseman FK. Genetic dissection of down syndrome-associated alterations in APP/amyloid-β biology using mouse models. Scientific Reports. 11: 5736. PMID 33707583 DOI: 10.1038/s41598-021-85062-3   
2021 Cai T, Tomita T. Sequential conformational changes in transmembrane domains of presenilin 1 in Aβ42 downregulation. Journal of Biochemistry. PMID 33739423 DOI: 10.1093/jb/mvab033   
2021 Lau JKY, Tian M, Shen Y, Lau SF, Fu WY, Fu AKY, Ip NY. Melanocortin receptor activation alleviates amyloid pathology and glial reactivity in an Alzheimer's disease transgenic mouse model. Scientific Reports. 11: 4359. PMID 33623128 DOI: 10.1038/s41598-021-83932-4   
2021 Khan A, Das S, Sergi C. Therapeutic Potential of Neu1 in Alzheimer's Disease Via the Immune System. American Journal of Alzheimer's Disease and Other Dementias. 36: 1533317521996147. PMID 33719595 DOI: 10.1177/1533317521996147   
2021 Paulus A, Engdahl A, Yang Y, Boza-Serrano A, Bachiller S, Torres-Garcia L, Svanbergsson A, Garcia MG, Gouras GK, Li JY, Deierborg T, Klementieva O. Amyloid Structural Changes Studied by Infrared Microspectroscopy in Bigenic Cellular Models of Alzheimer's Disease. International Journal of Molecular Sciences. 22. PMID 33810433 DOI: 10.3390/ijms22073430   
2021 Miranda A, Montiel E, Ulrich H, Paz C. Selective Secretase Targeting for Alzheimer's Disease Therapy. Journal of Alzheimer's Disease : Jad. PMID 33749645 DOI: 10.3233/JAD-201027   
2021 Yoon JH, Lee N, Youn K, Jo MR, Kim HR, Lee DS, Ho CT, Jun M. Dieckol Ameliorates Aβ Production via PI3K/Akt/GSK-3β Regulated APP Processing in SweAPP N2a Cell. Marine Drugs. 19. PMID 33804171 DOI: 10.3390/md19030152   
2021 Jiang H, Niu F, Zheng Y, Xu Y. CART mitigates oxidative stress and DNA damage in memory deficits of APP/PS1 mice via upregulating β‑amyloid metabolism‑associated enzymes. Molecular Medicine Reports. 23: 1-12. PMID 33604684 DOI: 10.3892/mmr.2021.11919   
2021 Foley AR, Raskatov JA. Understanding and controlling amyloid aggregation with chirality. Current Opinion in Chemical Biology. 64: 1-9. PMID 33610939 DOI: 10.1016/j.cbpa.2021.01.003   
2021 Lee JH, Ahn NH, Choi SB, Kwon Y, Yang SH. Natural Products Targeting Amyloid Beta in Alzheimer's Disease. International Journal of Molecular Sciences. 22. PMID 33652858 DOI: 10.3390/ijms22052341   
2021 Locci A, Orellana H, Rodriguez G, Gottliebson M, McClarty B, Dominguez S, Keszycki R, Dong H. Comparison of memory, affective behavior, and neuropathology in APP knock-in mice to 5xFAD and APP/PS1 mice. Behavioural Brain Research. 113192. PMID 33607163 DOI: 10.1016/j.bbr.2021.113192   
2021 Zhang X, Zhang CM, Prokopenko D, Liang Y, Zhen SY, Weigle IQ, Han W, Aryal M, Tanzi RE, Sisodia SS. An APP ectodomain mutation outside of the Aβ domain promotes Aβ production in vitro and deposition in vivo. The Journal of Experimental Medicine. 218. PMID 33822840 DOI: 10.1084/jem.20210313   
2021 Maeda J, Minamihisamatsu T, Shimojo M, Zhou X, Ono M, Matsuba Y, Ji B, Ishii H, Ogawa M, Akatsu H, Kaneda D, Hashizume Y, Robinson JL, Lee VM, Saito T, et al. Distinct microglial response against Alzheimer's amyloid and tau pathologies characterized by P2Y12 receptor. Brain Communications. 3: fcab011. PMID 33644757 DOI: 10.1093/braincomms/fcab011   
2021 Delgado A, Cholevas C, Theoharides TC. Neuroinflammation in Alzheimer's disease and beneficial action of luteolin. Biofactors (Oxford, England). PMID 33615581 DOI: 10.1002/biof.1714   
2021 Qiu Z, Shen Q, Jiang C, Yao L, Sun X, Li J, Duan C, Li R, Li X, Gopinath SCB, Anbu P, Lakshmipriya T, Li X. Alzheimer's Disease Determination by a Dual Probe on Gold Nanourchins and Nanohorn Hybrids. International Journal of Nanomedicine. 16: 2311-2322. PMID 33776435 DOI: 10.2147/IJN.S302396   
2021 Gerrits E, Brouwer N, Kooistra SM, Woodbury ME, Vermeiren Y, Lambourne M, Mulder J, Kummer M, Möller T, Biber K, Dunnen WFAD, De Deyn PP, Eggen BJL, Boddeke EWGM. Distinct amyloid-β and tau-associated microglia profiles in Alzheimer's disease. Acta Neuropathologica. PMID 33609158 DOI: 10.1007/s00401-021-02263-w   
2021 Alakbarzade V, French JM, Howlett DR, Attems J, Francis PT, Stratton S, Clark CN, Pereira AC, Hainsworth AH. Cerebral amyloid angiopathy distribution in older people: A cautionary note. Alzheimer's & Dementia (New York, N. Y.). 7: e12145. PMID 33644295 DOI: 10.1002/trc2.12145   
2021 Koh SH, Kwon HS, Choi SH, Jeong JH, Na HR, Lee CN, Yang Y, Lee AY, Lee JH, Park KW, Han HJ, Kim BC, Park JS, Lee JY, Kim S, et al. Efficacy and safety of GV1001 in patients with moderate-to-severe Alzheimer's disease already receiving donepezil: a phase 2 randomized, double-blind, placebo-controlled, multicenter clinical trial. Alzheimer's Research & Therapy. 13: 66. PMID 33771205 DOI: 10.1186/s13195-021-00803-w   
2021 Ackley SF, Zimmerman SC, Brenowitz WD, Tchetgen Tchetgen EJ, Gold AL, Manly JJ, Mayeda ER, Filshtein TJ, Power MC, Elahi FM, Brickman AM, Glymour MM. Effect of reductions in amyloid levels on cognitive change in randomized trials: instrumental variable meta-analysis. Bmj (Clinical Research Ed.). 372: n156. PMID 33632704 DOI: 10.1136/bmj.n156   
2021 Bansal A, Schmidt M, Rennegarbe M, Haupt C, Liberta F, Stecher S, Puscalau-Girtu I, Biedermann A, Fändrich M. AA amyloid fibrils from diseased tissue are structurally different from in vitro formed SAA fibrils. Nature Communications. 12: 1013. PMID 33579941 DOI: 10.1038/s41467-021-21129-z   
2021 Abbaszadeh M, Sahin M, Ozgun A, Oncu G, Garipcan B, Saybasili H. A Transient Survival Model of Alteration of Electrophysiological Properties Due to Amyloid-Beta Toxicity Based on SH-SY5Y Cell Line. Current Alzheimer Research. PMID 33583383 DOI: 10.2174/1567205018666210212155750   
2021 Ashford MT, Veitch DP, Neuhaus J, Nosheny RL, Tosun D, Weiner MW. The search for a convenient procedure to detect one of the earliest signs of Alzheimer's disease: A systematic review of the prediction of brain amyloid status. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 33583100 DOI: 10.1002/alz.12253   
2021 Singh YP, Rai H, Singh G, Singh GK, Mishra S, Kumar S, Srikrishna S, Modi G. A review on ferulic acid and analogs based scaffolds for the management of Alzheimer's disease. European Journal of Medicinal Chemistry. 215: 113278. PMID 33662757 DOI: 10.1016/j.ejmech.2021.113278   
2021 Shin JH, Hwang YS, Jung BK, Seo SH, Ham DW, Shin EH. Reduction of Amyloid Burden by Proliferated Homeostatic Microglia in -Infected Alzheimer's Disease Model Mice. International Journal of Molecular Sciences. 22. PMID 33803262 DOI: 10.3390/ijms22052764   
2021 Soto-Rojas LO, Pacheco-Herrero M, Martínez-Gómez PA, Campa-Córdoba BB, Apátiga-Pérez R, Villegas-Rojas MM, Harrington CR, de la Cruz F, Garcés-Ramírez L, Luna-Muñoz J. The Neurovascular Unit Dysfunction in Alzheimer's Disease. International Journal of Molecular Sciences. 22. PMID 33670754 DOI: 10.3390/ijms22042022   
2021 Mintun MA, Lo AC, Duggan Evans C, Wessels AM, Ardayfio PA, Andersen SW, Shcherbinin S, Sparks J, Sims JR, Brys M, Apostolova LG, Salloway SP, Skovronsky DM. Donanemab in Early Alzheimer's Disease. The New England Journal of Medicine. PMID 33720637 DOI: 10.1056/NEJMoa2100708   
2021 Yoo JY, Kim HB, Baik TK, Lee JH, Woo RS. Neuregulin 1/ErbB4/Akt signaling attenuates cytotoxicity mediated by the APP-CT31 fragment of amyloid precursor protein. Experimental and Molecular Pathology. 104622. PMID 33684392 DOI: 10.1016/j.yexmp.2021.104622   
2021 Al-Thani HF, Ahmad MN, Younes S, Zayed H. Genetic Variants Associated With Alzheimer Disease in the 22 Arab Countries: A Systematic Review. Alzheimer Disease and Associated Disorders. PMID 33769987 DOI: 10.1097/WAD.0000000000000447   
2021 Yang J, Perrett S, Wu S. Single Molecule Characterization of Amyloid Oligomers. Molecules (Basel, Switzerland). 26. PMID 33670093 DOI: 10.3390/molecules26040948   
2021 Gao J, Suo C, Tseng JH, Moss MA, Terry AV, Chapman J. Design and Synthesis of Ranitidine Analogs as Multi-Target Directed Ligands for the Treatment of Alzheimer's Disease. International Journal of Molecular Sciences. 22. PMID 33803769 DOI: 10.3390/ijms22063120   
2021 Leinenga G, Koh WK, Götz J. A comparative study of the effects of Aducanumab and scanning ultrasound on amyloid plaques and behavior in the APP23 mouse model of Alzheimer disease. Alzheimer's Research & Therapy. 13: 76. PMID 33836798 DOI: 10.1186/s13195-021-00809-4   
2021 Khan MS, Ikram M, Park TJ, Kim MO. Pathology, Risk Factors, and Oxidative Damage Related to Type 2 Diabetes-Mediated Alzheimer's Disease and the Rescuing Effects of the Potent Antioxidant Anthocyanin. Oxidative Medicine and Cellular Longevity. 2021: 4051207. PMID 33728019 DOI: 10.1155/2021/4051207   
2021 Gaudreault R, Hervé V, van de Ven TGM, Mousseau N, Ramassamy C. Polyphenol-Peptide Interactions in Mitigation of Alzheimer's Disease: Role of Biosurface-Induced Aggregation. Journal of Alzheimer's Disease : Jad. PMID 33749653 DOI: 10.3233/JAD-201549   
2021 Husain MA, Laurent B, Plourde M. APOE and Alzheimer's Disease: From Lipid Transport to Physiopathology and Therapeutics. Frontiers in Neuroscience. 15: 630502. PMID 33679311 DOI: 10.3389/fnins.2021.630502   
2021 Wu T, Chen L, Zhou L, Xu J, Guo K. Platelets transport β-amyloid from the peripheral blood into the brain by destroying the blood-brain barrier to accelerate the process of Alzheimer's disease in mouse models. Aging. 13. PMID 33668038 DOI: 10.18632/aging.202662   
2021 Wang YY, Huang ZT, Yuan MH, Jing F, Cai RL, Zou Q, Pu YS, Wang SY, Chen F, Yi WM, Zhang HJ, Cai ZY. Role of Hypoxia Inducible Factor-1α in Alzheimer's Disease. Journal of Alzheimer's Disease : Jad. PMID 33612545 DOI: 10.3233/JAD-201448   
2021 Takahashi RH, Yokotsuka M, Tobiume M, Sato Y, Hasegawa H, Nagao T, Gouras GK. Accumulation of cellular prion protein within β-amyloid oligomer plaques in aged human brains. Brain Pathology (Zurich, Switzerland). e12941. PMID 33624334 DOI: 10.1111/bpa.12941   
2021 Fairley LH, Sahara N, Aoki I, Ji B, Suhara T, Higuchi M, Barron AM. Neuroprotective effect of mitochondrial translocator protein ligand in a mouse model of tauopathy. Journal of Neuroinflammation. 18: 76. PMID 33740987 DOI: 10.1186/s12974-021-02122-1   
2021 Deng Z, Wang J, Xiao Y, Li F, Niu L, Liu X, Meng L, Zheng H. Ultrasound-mediated augmented exosome release from astrocytes alleviates amyloid-β-induced neurotoxicity. Theranostics. 11: 4351-4362. PMID 33754065 DOI: 10.7150/thno.52436   
2021 Bretland KA, Lin L, Bretland KM, Smith MA, Fleming SM, Dengler-Crish CM. Irisin treatment lowers levels of phosphorylated tau in the hippocampus of pre-symptomatic female but not male htau mice. Neuropathology and Applied Neurobiology. PMID 33768561 DOI: 10.1111/nan.12711   
2021 Zhang Y, Zhang M, Liu Y, Zhang D, Tang Y, Ren B, Zheng J. Dual amyloid cross-seeding reveals steric zipper-facilitated fibrillization and pathological links between protein misfolding diseases. Journal of Materials Chemistry. B. PMID 33651875 DOI: 10.1039/d0tb02958k   
2021 Cash MK, Rockwood K, Fisk JD, Darvesh S. Clinicopathological correlations and cholinesterase expression in early-onset familial Alzheimer's disease with the presenilin 1 mutation, Leu235Pro. Neurobiology of Aging. 103: 31-41. PMID 33789210 DOI: 10.1016/j.neurobiolaging.2021.02.025   
2021 Möllers T, Stocker H, Perna L, Nabers A, Rujescu D, Hartmann AM, Holleczek B, Schöttker B, Gerwert K, Brenner H. Aβ misfolding in blood plasma measured by immuno-infrared-sensor as an age-independent risk marker of Alzheimer's disease. Alzheimer's & Dementia (Amsterdam, Netherlands). 13: e12151. PMID 33614887 DOI: 10.1002/dad2.12151