John Hines, Ph.D. - Publications

Affiliations: 
2000 University of Pennsylvania, Philadelphia, PA, United States 

29 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2015 Lu J, Qian Y, Altieri M, Dong H, Wang J, Raina K, Hines J, Winkler JD, Crew AP, Coleman K, Crews CM. Hijacking the E3 Ubiquitin Ligase Cereblon to Efficiently Target BRD4. Chemistry & Biology. 22: 755-63. PMID 26051217 DOI: 10.1016/J.Chembiol.2015.05.009  0.96
2013 Hines J, Gough JD, Corson TW, Crews CM. Posttranslational protein knockdown coupled to receptor tyrosine kinase activation with phosphoPROTACs. Proceedings of the National Academy of Sciences of the United States of America. 110: 8942-7. PMID 23674677 DOI: 10.1073/Pnas.1217206110  0.96
2012 Holman EC, Campbell LJ, Hines J, Crews CM. Microarray analysis of microRNA expression during axolotl limb regeneration. Plos One. 7: e41804. PMID 23028429 DOI: 10.1371/Journal.Pone.0041804  0.96
2011 Tae HS, Hines J, Schneekloth AR, Crews CM. Unexpected stereochemical tolerance for the biological activity of tyroscherin. Bioorganic & Medicinal Chemistry. 19: 1708-13. PMID 21315614 DOI: 10.1016/J.Bmc.2011.01.027  0.96
2010 Tae HS, Hines J, Schneekloth AR, Crews CM. Total synthesis and biological evaluation of tyroscherin. Organic Letters. 12: 4308-11. PMID 20831175 DOI: 10.1021/Ol101801U  0.96
2010 Hines J, Ju R, Dutschman GE, Cheng YC, Crews CM. Reversal of TNP-470-induced endothelial cell growth arrest by guanine and guanine nucleosides. The Journal of Pharmacology and Experimental Therapeutics. 334: 729-38. PMID 20571059 DOI: 10.1124/Jpet.110.169110  0.96
2009 Custar DW, Zabawa TP, Hines J, Crews CM, Scheidt KA. Total synthesis and structure-activity investigation of the marine natural product neopeltolide. Journal of the American Chemical Society. 131: 12406-14. PMID 19663512 DOI: 10.1021/Ja904604X  0.96
2008 Hines J, Groll M, Fahnestock M, Crews CM. Proteasome inhibition by fellutamide B induces nerve growth factor synthesis. Chemistry & Biology. 15: 501-12. PMID 18482702 DOI: 10.1016/J.Chembiol.2008.03.020  0.96
2006 Zhang Y, Yeh JR, Mara A, Ju R, Hines JF, Cirone P, Griesbach HL, Schneider I, Slusarski DC, Holley SA, Crews CM. A chemical and genetic approach to the mode of action of fumagillin. Chemistry & Biology. 13: 1001-9. PMID 16984890 DOI: 10.1016/J.Chembiol.2006.07.010  0.96
2006 Hines J, Roy M, Cheng H, Agapakis CM, Taylor R, Crews CM. Myriaporone 3/4 structure--activity relationship studies define a pharmacophore targeting eukaryotic protein synthesis. Molecular Biosystems. 2: 371-9. PMID 16880957 DOI: 10.1039/B602936A  0.96
2006 Schneekloth JS, Sanders JL, Hines J, Crews CM. Neurotrophic peptide aldehydes: solid phase synthesis of fellutamide B and a simplified analog. Bioorganic & Medicinal Chemistry Letters. 16: 3855-8. PMID 16697191 DOI: 10.1016/J.Bmcl.2006.04.029  0.96
2005 Hines J. Small molecules driving myotube fission. Chemistry & Biology. 12: 1058-60. PMID 16242647 DOI: 10.1016/j.chembiol.2005.10.001  0.96
2005 Mandal AK, Hines J, Kuramochi K, Crews CM. Developing microcolin A analogs as biological probes. Bioorganic & Medicinal Chemistry Letters. 15: 4043-7. PMID 15993592 DOI: 10.1016/J.Bmcl.2005.06.020  0.96
2005 Videlock EJ, Chung VK, Hall JM, Hines J, Agapakis CM, Austin DJ. Identification of a molecular recognition role for the activation loop phosphotyrosine of the SRC tyrosine kinase. Journal of the American Chemical Society. 127: 1600-1. PMID 15700969 DOI: 10.1021/Ja047957C  0.96
2003 Hines J, Fluharty SJ, Yee DK. Structural determinants for the activation mechanism of the angiotensin II type 1 receptor differ for phosphoinositide hydrolysis and mitogen-activated protein kinase pathways. Biochemical Pharmacology. 66: 251-62. PMID 12826267 DOI: 10.1016/S0006-2952(03)00257-0  0.96
2002 Shotwell JB, Krygowski ES, Hines J, Koh B, Huntsman EW, Choi HW, Schneekloth JS, Wood JL, Crews CM. Total synthesis of luminacin D. Organic Letters. 4: 3087-9. PMID 12201723 DOI: 10.1021/Ol026382Q  0.96
2001 Hines J, Fluharty SJ, Yee DK. Chimeric AT1/AT2 receptors reveal functional similarities despite key amino acid dissimilarities in the domains mediating agonist-dependent activation. Biochemistry. 40: 11251-60. PMID 11551225 DOI: 10.1021/Bi002780U  0.96
2001 Hines J, Heerding JN, Fluharty SJ, Yee DK. Identification of angiotensin II type 2 (AT2) receptor domains mediating high-affinity CGP 42112A binding and receptor activation. The Journal of Pharmacology and Experimental Therapeutics. 298: 665-73. PMID 11454929  0.96
2001 Heerding JN, Hines J, Fluharty SJ, Yee DK. Identification and function of disulfide bridges in the extracellular domains of the angiotensin II type 2 receptor. Biochemistry. 40: 8369-77. PMID 11444984 DOI: 10.1021/Bi002805P  0.96
2001 Peng H, Moffett J, Myers J, Fang X, Stachowiak EK, Maher P, Kratz E, Hines J, Fluharty SJ, Mizukoshi E, Bloom DC, Stachowiak MK. Novel nuclear signaling pathway mediates activation of fibroblast growth factor-2 gene by type 1 and type 2 angiotensin II receptors. Molecular Biology of the Cell. 12: 449-62. PMID 11179427 DOI: 10.1091/Mbc.12.2.449  0.96
1999 Hines J, Fluharty SJ, Sakai RR. The angiotensin AT(1) receptor antagonist irbesartan has near-peptide affinity and potently blocks receptor signaling. European Journal of Pharmacology. 384: 81-9. PMID 10611423 DOI: 10.1016/S0014-2999(99)00662-7  0.96
1997 Yee DK, He P, Yang XD, Reagan LP, Hines J, Siemens IR, Fluharty SJ. Cloning and expression of angiotensin II type 2 (AT2) receptors from murine neuroblastoma N1E-115 cells: evidence for AT2 receptor heterogeneity. Brain Research. Molecular Brain Research. 45: 108-16. PMID 9105676 DOI: 10.1016/S0169-328X(96)00242-2  0.96
1996 Raynor K, Kong H, Law S, Heerding J, Tallent M, Livingston F, Hines J, Reisine T. Molecular biology of opioid receptors. Nida Research Monograph. 161: 83-103. PMID 8784846  0.96
1995 Reisine T, Woulfe D, Raynor K, Kong H, Heerding J, Hines J, Tallent M, Law S. Interaction of somatostatin receptors with G proteins and cellular effector systems. Ciba Foundation Symposium. 190: 160-7; discussion 16. PMID 7587645  0.96
1994 Raynor K, Kong H, Hines J, Kong G, Benovic J, Yasuda K, Bell GI, Reisine T. Molecular mechanisms of agonist-induced desensitization of the cloned mouse kappa opioid receptor Journal of Pharmacology and Experimental Therapeutics. 270: 1381-1386. PMID 7932192  0.96
1982 Edwards JA, Hines JF. Rapidly transported proteins released from nerve and isolated with myelin Brain Research. 239: 507-517. PMID 6178470 DOI: 10.1016/0006-8993(82)90525-X  0.96
1977 Hines JF, Garwood MM. Release of protein from axons during rapid axonal transport: An in vitro preparation Brain Research. 125: 141-148. PMID 66966 DOI: 10.1016/0006-8993(77)90365-1  0.96
1971 Hines JF, Easton DM. Efflux of endogenous protein from non-myelinated olfactory nerve as monitored by tryptophan fluorescence Journal of Neurochemistry. 18: 2155-2169. PMID 5129352  0.96
1971 Easton DM, Lipner H, Hines J, Leif RC. Fluorescence monitoring of unstained protein bands in acrylamide gel Analytical Biochemistry. 39: 478-486. PMID 4101990 DOI: 10.1016/0003-2697(71)90437-4  0.96
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