Sunita Joshi, Ph.D. - Related publications

2014 Cellular and Molecular Bio University of Wisconsin, Madison, Madison, WI 
Ion Channels
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50 most relevant papers in past 60 days:
Year Citation  Score
2021 Silic MR, Murata SH, Park SJ, Zhang G. Evolution of inwardly rectifying potassium channels and their gene expression in zebrafish embryos. Developmental Dynamics : An Official Publication of the American Association of Anatomists. PMID 34558132 DOI: 10.1002/dvdy.425   
2021 Jæger KH, Edwards AG, Giles WR, Tveito A. A computational method for identifying an optimal combination of existing drugs to repair the action potentials of SQT1 ventricular myocytes. Plos Computational Biology. 17: e1009233. PMID 34383746 DOI: 10.1371/journal.pcbi.1009233   
2021 Souza IA, Gandini MA, Zamponi GW. Splice-variant specific effects of a CACNA1H mutation associated with writer's cramp. Molecular Brain. 14: 145. PMID 34544471 DOI: 10.1186/s13041-021-00861-z   
2021 Peng KY, Liao HW, Chueh JS, Pan CY, Lin YH, Chen YM, Chen PY, Huang CL, Wu VC. Pathophysiological and Pharmacological Characteristics of 157-159delITE Somatic Mutation in Aldosterone-Producing Adenomas. Biomedicines. 9. PMID 34440230 DOI: 10.3390/biomedicines9081026   
2021 Hu Y, Li Q, Shen Y, Fujita T, Zhu X, Inoue R. Theoretical Investigation of the Mechanism by which A Gain-of-Function Mutation of the TRPM4 Channel Causes Conduction Block. International Journal of Molecular Sciences. 22. PMID 34445219 DOI: 10.3390/ijms22168513   
2021 Wu F, Quinonez M, Cannon SC. Gating pore currents occur in CaV1.1 domain III mutants associated with HypoPP. The Journal of General Physiology. 153. PMID 34463712 DOI: 10.1085/jgp.202112946   
2021 Huang YN, Yang SY, Li JL, Wang SF, Wang JJ, Hao DL, Su YH. The rectification control and physiological relevance of potassium channel OsAKT2. Plant Physiology. PMID 34601582 DOI: 10.1093/plphys/kiab462   
2021 Liu M, Ge N, Zhang J, Yang M, Yang F, Krawczyk J, Ward D, McInerney V, O'Brien T, Shen S, Prendiville T. Derivation and characterization of two human induced pluripotent stem cell lines (NUIGi004-A) and (NUIGi012-A) from two patients with LQT2 disease. Stem Cell Research. 56: 102555. PMID 34628246 DOI: 10.1016/j.scr.2021.102555   
2021 Yu H, Gall B, Newman M, Hathaway Q, Brundage K, Ammer A, Mathers P, Siderovski D, Hull RW. Contribution of HCN1 variant to sinus bradycardia: A case report. Journal of Arrhythmia. 37: 1337-1347. PMID 34621433 DOI: 10.1002/joa3.12598   
2021 Pierre M, Djemai M, Poulin H, Chahine M. Na1.5 knockout in iPSCs: a novel approach to study Na1.5 variants in a human cardiomyocyte environment. Scientific Reports. 11: 17168. PMID 34433864 DOI: 10.1038/s41598-021-96474-6   
2021 Schwartz PJ, Moreno C, Kotta MC, Pedrazzini M, Crotti L, Dagradi F, Castelletti S, Haugaa KH, Denjoy I, Shkolnikova MA, Brink PA, Heradien MJ, Seyen SRM, Spätjens RLHMG, Spazzolini C, et al. Mutation location and IKs regulation in the arrhythmic risk of long QT syndrome type 1: the importance of the KCNQ1 S6 region. European Heart Journal. PMID 34505893 DOI: 10.1093/eurheartj/ehab582   
2021 Reddy HP, Yakubovich D, Keren-Raifman T, Tabak G, Tsemakhovich VA, Pedersen MH, Shalomov B, Colombo S, Goldstein DB, Javitch JA, Bera AK, Dascal N. Encephalopathy-causing mutations in Gβ () alter regulation of neuronal GIRK channels. Iscience. 24: 103018. PMID 34522861 DOI: 10.1016/j.isci.2021.103018   
2021 Jiang D, Banh R, Gamal El-Din TM, Tonggu L, Lenaeus MJ, Pomès R, Zheng N, Catterall WA. Open-state structure and pore gating mechanism of the cardiac sodium channel. Cell. PMID 34520724 DOI: 10.1016/j.cell.2021.08.021   
2021 Gao X, Yu S, Guan Y, Shen Y, Xu L. Nucleoporin 50 mediates Kcna4 transcription to regulate cardiac electrical activity. Journal of Cell Science. PMID 34409458 DOI: 10.1242/jcs.256818   
2021 Sun J, Pan S, Karey E, Chen YJ, Pinkerton KE, Wilson CG, Chen CY. Secondhand Smoke Decreased Excitability and Altered Action Potential Characteristics of Cardiac Vagal Neurons in Mice. Frontiers in Physiology. 12: 727000. PMID 34630146 DOI: 10.3389/fphys.2021.727000   
2021 Vigneault P, Parent S, Kanda P, Michie C, Davis DR, Nattel S. Electrophysiological engineering of heart-derived cells with calcium-dependent potassium channels improves cell therapy efficacy for cardioprotection. Nature Communications. 12: 4963. PMID 34400625 DOI: 10.1038/s41467-021-25180-8   
2021 Jie LJ, Li YD, Zhang HQ, Mao L, Xie HB, Zhou FG, Zhou TL, Xie D, Lin JL, Li GY, Cai BN, Zhang YH, Wang Y. Mechanisms of gefitinib-induced QT prolongation. European Journal of Pharmacology. 174441. PMID 34474028 DOI: 10.1016/j.ejphar.2021.174441   
2021 Qie X, Du Y, Aioub AAA, Dong K, Hu Z. Negative cross-resistance of a pyrethroid-resistant Drosophila mutant to Phryma leptostachya-derived haedoxan A. Insect Science. PMID 34547832 DOI: 10.1111/1744-7917.12973   
2021 Chuang TH, Cho HY, Wu SN. Effective Accentuation of Voltage-Gated Sodium Current Caused by Apocynin (4'-Hydroxy-3'-methoxyacetophenone), a Known NADPH-Oxidase Inhibitor. Biomedicines. 9. PMID 34572332 DOI: 10.3390/biomedicines9091146   
2021 Ördög B, Teplenin A, De Coster T, Bart CI, Dekker SO, Zhang J, Ypey DL, de Vries AAF, Pijnappels DA. The Effects of Repetitive Use and Pathological Remodeling on Channelrhodopsin Function in Cardiomyocytes. Frontiers in Physiology. 12: 710020. PMID 34539432 DOI: 10.3389/fphys.2021.710020   
2021 Jiang N, Zhou A, Imran H, Shi G, Kaseer B, Siu V, Chu AF, Donaldson DM, Kirk MM, Philips BB, Dudley SC. Cardiac Resynchronization and Circulating Markers of Sarcoplasmic Reticulum Calcium Handling and Sudden Death Risk. Jacc. Clinical Electrophysiology. PMID 34454876 DOI: 10.1016/j.jacep.2021.07.003   
2021 Peng DW, Lai YY, Luo X, Li X, Deng CY, Guo HM, Zhao JF, Yang H, Liu Y, Wang ZY, Xu YW, Kuang SJ, Wu SL, Xue YM, Rao F. Connexin 43 participates in atrial electrical remodeling through colocalization with calcium channels in atrial myocytes. Clinical and Experimental Pharmacology & Physiology. PMID 34438468 DOI: 10.1111/1440-1681.13580   
2021 Zhu F, Miao Y, Cheng M, Ye X, Chen A, Zheng G, Tian X. The CACNA1A Mutant Disrupts Lysosome Calcium Homeostasis in Cerebellar Neurons and the Resulting Endo-Lysosomal Fusion Defect Can be Improved by Calcium Modulation. Neurochemical Research. PMID 34476720 DOI: 10.1007/s11064-021-03438-3   
2021 Yang YS, Choi JH, Rah JC. Hypoxia with inflammation and reperfusion alters membrane resistance by dynamically regulating voltage-gated potassium channels in hippocampal CA1 neurons. Molecular Brain. 14: 147. PMID 34556177 DOI: 10.1186/s13041-021-00857-9   
2021 Bothe SN, Lampert A. The insecticide deltamethrin enhances sodium channel slow inactivation of human Nav1.9, Nav1.8 and Nav1.7. Toxicology and Applied Pharmacology. 428: 115676. PMID 34389319 DOI: 10.1016/j.taap.2021.115676   
2021 Kodirov SA, Brachmann J, Safonova TA, Zhuravlev VL. Inactivation of Native K Channels. The Journal of Membrane Biology. PMID 34383081 DOI: 10.1007/s00232-021-00195-w   
2021 Jiang S, Bloomquist JR. Enhanced pyrethroid potency in Drosophila melanogaster expressing voltage-gated potassium channel mutants: Insecticidal activity and neuronal action. Pesticide Biochemistry and Physiology. 178: 104940. PMID 34446207 DOI: 10.1016/j.pestbp.2021.104940   
2021 Amberg GC, Lee JY, Don Koh S, Sanders KM. Characterization of the A-Type potassium current in murine gastric fundus smooth muscles. American Journal of Physiology. Cell Physiology. PMID 34432539 DOI: 10.1152/ajpcell.00247.2021   
2021 Nissenkorn A, Kornilov P, Peretz A, Blumkin L, Heimer G, Ben-Zeev B, Attali B. Personalized treatment with retigabine for pharmacoresistant epilepsy arising from a pathogenic variant in the KCNQ2 selectivity filter. Epileptic Disorders : International Epilepsy Journal With Videotape. PMID 34519644 DOI: 10.1684/epd.2021.1315   
2021 Nakamura M, Jang IS. Propranolol modulation of tetrodotoxin-resistant Na channels in dural afferent neurons. European Journal of Pharmacology. 910: 174449. PMID 34454925 DOI: 10.1016/j.ejphar.2021.174449   
2021 Ishihara M, Kojima A, Ding WG, Kitagawa H, Matsuura H. Dexmedetomidine exerts a negative chronotropic action on sinoatrial node cells through the activation of imidazoline receptors. Journal of Cardiovascular Pharmacology. PMID 34448469 DOI: 10.1097/FJC.0000000000001133   
2021 Anderson A, Vo BN, Marron Fernandez de Velasco E, Hopkins CR, Weaver CD, Wickman K. . Molecular Pharmacology. PMID 34503975 DOI: 10.1124/molpharm.121.000311   
2021 Qian LL, Sun X, Yang J, Wang XL, Ackerman MJ, Wang RX, Xu X, Lee HC, Lu T. Changes in ion channel expression and function associated with cardiac arrhythmogenic remodeling by Sorbs2. Biochimica Et Biophysica Acta. Molecular Basis of Disease. 166247. PMID 34487812 DOI: 10.1016/j.bbadis.2021.166247   
2021 Qauli AI, Marcellinus A, Lim KM. Sensitivity Analysis of Ion Channel Conductance on Myocardial Electromechanical Delay: Computational Study. Frontiers in Physiology. 12: 697693. PMID 34512377 DOI: 10.3389/fphys.2021.697693   
2021 Wu X, Hoeker GS, Blair G, King DR, Gourdie RG, Weinberg SH, Poelzing S. Hypernatremia and Intercalated Disc Edema Synergistically Exacerbate Long QT Syndrome Type 3 Phenotype. American Journal of Physiology. Heart and Circulatory Physiology. PMID 34623182 DOI: 10.1152/ajpheart.00366.2021   
2021 Uryash A, Mijares A, Flores V, Adams JA, Lopez JR. Effects of Naringin on Cardiomyocytes From a Rodent Model of Type 2 Diabetes. Frontiers in Pharmacology. 12: 719268. PMID 34497520 DOI: 10.3389/fphar.2021.719268   
2021 Chen Y, Hu X, Cui J, Zhao M, Yao H. A novel mutation KCNJ11 R136C caused KCNJ11-MODY. Diabetology & Metabolic Syndrome. 13: 91. PMID 34465386 DOI: 10.1186/s13098-021-00708-6   
2021 Liu QH, Zhang LJ, Wang J, Wu BW, Cao JM. Cardioprotection of an I channel agonist on L-thyroxine induced rat ventricular remodeling. American Journal of Translational Research. 13: 8683-8696. PMID 34539987   
2021 Balducci V, Credi C, Sacconi L, Romanelli MN, Sartiani L, Cerbai E. The HCN channel as a pharmacological target: Why, where, and how to block it. Progress in Biophysics and Molecular Biology. PMID 34303730 DOI: 10.1016/j.pbiomolbio.2021.07.010   
2021 Lauxmann S, Sonnenberg L, Koch NA, Bosselmann C, Winter N, Schwarz N, Wuttke TV, Hedrich UBS, Liu Y, Lerche H, Benda J, Kegele J. Therapeutic Potential of Sodium Channel Blockers as a Targeted Therapy Approach in -Associated Episodic Ataxia and a Comprehensive Review of the Literature. Frontiers in Neurology. 12: 703970. PMID 34566847 DOI: 10.3389/fneur.2021.703970   
2021 Glaser F, Hundehege P, Bulk E, Todesca LM, Schimmelpfennig S, Nass E, Budde T, Meuth SG, Schwab A. K channel blockers increase effectiveness of the EGF receptor TK inhibitor erlotinib in non-small cell lung cancer cells (A549). Scientific Reports. 11: 18330. PMID 34526525 DOI: 10.1038/s41598-021-97406-0   
2021 Obergrussberger A, Rinke-Weiß I, Goetze TA, Rapedius M, Brinkwirth N, Becker N, Rotordam MG, Hutchison L, Madau P, Pau D, Dalrymple D, Braun N, Friis S, Pless SA, Fertig N. The suitability of high throughput automated patch clamp for physiological applications. The Journal of Physiology. PMID 34555195 DOI: 10.1113/JP282107   
2021 Tiscione SA, Casas M, Horvath JD, Lam V, Hino K, Ory DS, Santana LF, Simó S, Dixon RE, Dickson EJ. IPR-driven increases in mitochondrial Ca promote neuronal death in NPC disease. Proceedings of the National Academy of Sciences of the United States of America. 118. PMID 34580197 DOI: 10.1073/pnas.2110629118   
2021 Rotordam MG, Obergrussberger A, Brinkwirth N, Takasuna K, Becker N, Horváth A, Goetze TA, Rapedius M, Furukawa H, Hasegawa Y, Oka T, Fertig N, Stoelzle-Feix S. Reliable identification of cardiac conduction abnormalities in drug discovery using automated patch clamp II: Best practices for Nav1.5 peak current in a high throughput screening environment. Journal of Pharmacological and Toxicological Methods. 107125. PMID 34500078 DOI: 10.1016/j.vascn.2021.107125   
2021 Alatrag F, Amoni M, Kelly-Laubscher R, Gwanyanya A. Cardioprotective effect of fingolimod against calcium paradox-induced myocardial injury in the isolated rat heart. Canadian Journal of Physiology and Pharmacology. PMID 34559972 DOI: 10.1139/cjpp-2021-0381   
2021 Jernigan NL, Naik JS, Resta TC. Acid-sensing ion channel 1 contributes to pulmonary arterial smooth muscle cell depolarization following hypoxic pulmonary hypertension. The Journal of Physiology. PMID 34487355 DOI: 10.1113/JP282231   
2021 Shimizu H, Huber S, Langenbacher AD, Crisman L, Huang J, Wang K, Wilting F, Gudermann T, Schredelseker J, Chen JN. Glutamate 73 Promotes Anti-arrhythmic Effects of Voltage-Dependent Anion Channel Through Regulation of Mitochondrial Ca Uptake. Frontiers in Physiology. 12: 724828. PMID 34483974 DOI: 10.3389/fphys.2021.724828   
2021 Turner D, Kang C, Mesirca P, Hong J, Mangoni ME, Glukhov AV, Sah R. Electrophysiological and Molecular Mechanisms of Sinoatrial Node Mechanosensitivity. Frontiers in Cardiovascular Medicine. 8: 662410. PMID 34434970 DOI: 10.3389/fcvm.2021.662410   
2021 Tóth N, Szlovák J, Kohajda Z, Bitay G, Veress R, Horváth B, Papp JG, Varró A, Nagy N. The development of L-type Ca current mediated alternans does not depend on the restitution slope in canine ventricular myocardium. Scientific Reports. 11: 16652. PMID 34404848 DOI: 10.1038/s41598-021-95299-7   
2021 Wang C, Maeda M, Chen J, Wang M, Naruse K, Takahashi K. Production of TRPM4 knockout cell line using rat cardiomyocyte H9c2. Methodsx. 8: 101404. PMID 34430300 DOI: 10.1016/j.mex.2021.101404