Mark von Zastrow - Publications

Affiliations: 
University of California, San Francisco, San Francisco, CA 

139 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2018 Lobingier BT, von Zastrow M. When trafficking and signaling mix: how subcellular location shapes GPCR activation of heterotrimeric G proteins. Traffic (Copenhagen, Denmark). PMID 30578610 DOI: 10.1111/tra.12634  1
2018 Stoeber M, Jullié D, Lobingier BT, Laeremans T, Steyaert J, Schiller PW, Manglik A, von Zastrow M. A Genetically Encoded Biosensor Reveals Location Bias of Opioid Drug Action. Neuron. PMID 29754753 DOI: 10.1016/j.neuron.2018.04.021  1
2016 Varandas KC, Irannejad R, von Zastrow M. Retromer Endosome Exit Domains Serve Multiple Trafficking Destinations and Regulate Local G Protein Activation by GPCRs. Current Biology : Cb. PMID 27839977 DOI: 10.1016/j.cub.2016.09.052  0.52
2015 Leaf A, Von Zastrow M. Dopamine receptors reveal an essential role of IFT-B, KIF17, and Rab23 in delivering specific receptors to primary cilia. Elife. 4. PMID 26182404 DOI: 10.7554/eLife.06996  1
2015 Irannejad R, Tsvetanova NG, Lobingier BT, von Zastrow M. Effects of endocytosis on receptor-mediated signaling. Current Opinion in Cell Biology. 35: 137-43. PMID 26057614 DOI: 10.1016/j.ceb.2015.05.005  1
2015 Koliwer J, Park M, Bauch C, von Zastrow M, Kreienkamp HJ. The golgi-associated PDZ domain protein PIST/GOPC stabilizes the β1-adrenergic receptor in intracellular compartments after internalization. The Journal of Biological Chemistry. 290: 6120-9. PMID 25614626 DOI: 10.1074/jbc.M114.605725  1
2015 Tsvetanova NG, Irannejad R, von Zastrow M. G protein-coupled receptor (GPCR) signaling via heterotrimeric G proteins from endosomes. The Journal of Biological Chemistry. 290: 6689-96. PMID 25605726 DOI: 10.1074/jbc.R114.617951  1
2014 Tsvetanova NG, von Zastrow M. Spatial encoding of cyclic AMP signaling specificity by GPCR endocytosis. Nature Chemical Biology. 10: 1061-5. PMID 25362359 DOI: 10.1038/nchembio.1665  1
2014 Di Fiore PP, von Zastrow M. Endocytosis, signaling, and beyond. Cold Spring Harbor Perspectives in Biology. 6. PMID 25085911 DOI: 10.1101/cshperspect.a016865  1
2014 Choy RW, Park M, Temkin P, Herring BE, Marley A, Nicoll RA, von Zastrow M. Retromer mediates a discrete route of local membrane delivery to dendrites. Neuron. 82: 55-62. PMID 24698268 DOI: 10.1016/j.neuron.2014.02.018  1
2014 Irannejad R, von Zastrow M. GPCR signaling along the endocytic pathway. Current Opinion in Cell Biology. 27: 109-16. PMID 24680436 DOI: 10.1016/j.ceb.2013.10.003  1
2014 Benovic JL, von Zastrow M. Editorial overview: Cell regulation: The ins and outs of G protein-coupled receptors. Current Opinion in Cell Biology. 27: v-vi. PMID 24529749 DOI: 10.1016/j.ceb.2014.01.009  1
2014 Irannejad R, Kotowski SJ, von Zastrow M. Investigating signaling consequences of GPCR trafficking in the endocytic pathway. Methods in Enzymology. 535: 403-18. PMID 24377936 DOI: 10.1016/B978-0-12-397925-4.00023-7  1
2013 Marley A, Choy RW, von Zastrow M. GPR88 reveals a discrete function of primary cilia as selective insulators of GPCR cross-talk. Plos One. 8: e70857. PMID 23936473 DOI: 10.1371/journal.pone.0070857  1
2013 Irannejad R, Tomshine JC, Tomshine JR, Chevalier M, Mahoney JP, Steyaert J, Rasmussen SG, Sunahara RK, El-Samad H, Huang B, von Zastrow M. Conformational biosensors reveal GPCR signalling from endosomes. Nature. 495: 534-8. PMID 23515162 DOI: 10.1038/nature12000  1
2013 Williams JT, Ingram SL, Henderson G, Chavkin C, von Zastrow M, Schulz S, Koch T, Evans CJ, Christie MJ. Regulation of μ-opioid receptors: desensitization, phosphorylation, internalization, and tolerance. Pharmacological Reviews. 65: 223-54. PMID 23321159 DOI: 10.1124/pr.112.005942  1
2013 Just S, Illing S, Trester-Zedlitz M, Lau EK, Kotowski SJ, Miess E, Mann A, Doll C, Trinidad JC, Burlingame AL, von Zastrow M, Schulz S. Differentiation of opioid drug effects by hierarchical multi-site phosphorylation. Molecular Pharmacology. 83: 633-9. PMID 23239825 DOI: 10.1124/mol.112.082875  1
2012 Marley A, von Zastrow M. A simple cell-based assay reveals that diverse neuropsychiatric risk genes converge on primary cilia. Plos One. 7: e46647. PMID 23056384 DOI: 10.1371/journal.pone.0046647  1
2012 von Zastrow M, Williams JT. Modulating neuromodulation by receptor membrane traffic in the endocytic pathway. Neuron. 76: 22-32. PMID 23040804 DOI: 10.1016/j.neuron.2012.09.022  1
2012 Henry AG, Hislop JN, Grove J, Thorn K, Marsh M, von Zastrow M. Regulation of endocytic clathrin dynamics by cargo ubiquitination. Developmental Cell. 23: 519-32. PMID 22940114 DOI: 10.1016/j.devcel.2012.08.003  1
2012 Avasthi P, Marley A, Lin H, Gregori-Puigjane E, Shoichet BK, von Zastrow M, Marshall WF. A chemical screen identifies class a g-protein coupled receptors as regulators of cilia. Acs Chemical Biology. 7: 911-9. PMID 22375814 DOI: 10.1021/cb200349v  1
2011 Hislop JN, Henry AG, von Zastrow M. Ubiquitination in the first cytoplasmic loop of μ-opioid receptors reveals a hierarchical mechanism of lysosomal down-regulation. The Journal of Biological Chemistry. 286: 40193-204. PMID 21953467 DOI: 10.1074/jbc.M111.288555  0.64
2011 Romero G, von Zastrow M, Friedman PA. Role of PDZ proteins in regulating trafficking, signaling, and function of GPCRs: means, motif, and opportunity. Advances in Pharmacology (San Diego, Calif.). 62: 279-314. PMID 21907913 DOI: 10.1016/B978-0-12-385952-5.00003-8  1
2011 Yudowski GA, von Zastrow M. Investigating G protein-coupled receptor endocytosis and trafficking by TIR-FM. Methods in Molecular Biology (Clifton, N.J.). 756: 325-32. PMID 21870236 DOI: 10.1007/978-1-61779-160-4_19  1
2011 Lau EK, Trester-Zedlitz M, Trinidad JC, Kotowski SJ, Krutchinsky AN, Burlingame AL, von Zastrow M. Quantitative encoding of the effect of a partial agonist on individual opioid receptors by multisite phosphorylation and threshold detection. Science Signaling. 4: ra52. PMID 21868358 DOI: 10.1126/scisignal.2001748  1
2011 Kotowski SJ, Hopf FW, Seif T, Bonci A, von Zastrow M. Endocytosis promotes rapid dopaminergic signaling. Neuron. 71: 278-90. PMID 21791287 DOI: 10.1016/j.neuron.2011.05.036  1
2011 Hislop JN, von Zastrow M. Analysis of GPCR localization and trafficking. Methods in Molecular Biology (Clifton, N.J.). 746: 425-40. PMID 21607873 DOI: 10.1007/978-1-61779-126-0_25  1
2011 Temkin P, Lauffer B, Jäger S, Cimermancic P, Krogan NJ, von Zastrow M. SNX27 mediates retromer tubule entry and endosome-to-plasma membrane trafficking of signalling receptors. Nature Cell Biology. 13: 715-21. PMID 21602791 DOI: 10.1038/ncb2252  1
2011 Quillinan N, Lau EK, Virk M, von Zastrow M, Williams JT. Recovery from mu-opioid receptor desensitization after chronic treatment with morphine and methadone. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 31: 4434-43. PMID 21430144 DOI: 10.1523/JNEUROSCI.4874-10.2011  1
2011 Henry AG, White IJ, Marsh M, von Zastrow M, Hislop JN. The role of ubiquitination in lysosomal trafficking of δ-opioid receptors. Traffic (Copenhagen, Denmark). 12: 170-84. PMID 21106040 DOI: 10.1111/j.1600-0854.2010.01145.x  1
2011 Hislop JN, von Zastrow M. Role of ubiquitination in endocytic trafficking of G-protein-coupled receptors. Traffic (Copenhagen, Denmark). 12: 137-48. PMID 20854416 DOI: 10.1111/j.1600-0854.2010.01121.x  1
2010 Puthenveedu MA, Lauffer B, Temkin P, Vistein R, Carlton P, Thorn K, Taunton J, Weiner OD, Parton RG, von Zastrow M. Sequence-dependent sorting of recycling proteins by actin-stabilized endosomal microdomains. Cell. 143: 761-73. PMID 21111236 DOI: 10.1016/j.cell.2010.10.003  0.76
2010 Tzingounis AV, von Zastrow M, Yudowski GA. {Beta}-blocker drugs mediate calcium signaling in native central nervous system neurons by {beta}-arrestin-biased agonism. Proceedings of the National Academy of Sciences of the United States of America. 107: 21028-33. PMID 21078978 DOI: 10.1073/pnas.1004169107  1
2010 Yu YJ, Dhavan R, Chevalier MW, Yudowski GA, von Zastrow M. Rapid delivery of internalized signaling receptors to the somatodendritic surface by sequence-specific local insertion. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 30: 11703-14. PMID 20810891 DOI: 10.1523/JNEUROSCI.6282-09.2010  1
2010 Lauffer BE, Melero C, Temkin P, Lei C, Hong W, Kortemme T, von Zastrow M. SNX27 mediates PDZ-directed sorting from endosomes to the plasma membrane. The Journal of Cell Biology. 190: 565-74. PMID 20733053 DOI: 10.1083/jcb.201004060  1
2010 Marley A, von Zastrow M. DISC1 regulates primary cilia that display specific dopamine receptors. Plos One. 5: e10902. PMID 20531939 DOI: 10.1371/journal.pone.0010902  1
2010 von Zastrow M. Regulation of opioid receptors by endocytic membrane traffic: mechanisms and translational implications. Drug and Alcohol Dependence. 108: 166-71. PMID 20338697 DOI: 10.1016/j.drugalcdep.2010.02.014  1
2010 Garriock HA, Tanowitz M, Kraft JB, Dang VC, Peters EJ, Jenkins GD, Reinalda MS, McGrath PJ, von Zastrow M, Slager SL, Hamilton SP. Association of mu-opioid receptor variants and response to citalopram treatment in major depressive disorder. The American Journal of Psychiatry. 167: 565-73. PMID 20194481 DOI: 10.1176/appi.ajp.2009.08081167  1
2010 Marley A, von Zastrow M. Dysbindin promotes the post-endocytic sorting of G protein-coupled receptors to lysosomes. Plos One. 5: e9325. PMID 20174469 DOI: 10.1371/journal.pone.0009325  1
2010 Rochdi MD, Vargas GA, Carpentier E, Oligny-Longpré G, Chen S, Kovoor A, Gitelman SE, Rosenthal SM, von Zastrow M, Bouvier M. Functional characterization of vasopressin type 2 receptor substitutions (R137H/C/L) leading to nephrogenic diabetes insipidus and nephrogenic syndrome of inappropriate antidiuresis: implications for treatments. Molecular Pharmacology. 77: 836-45. PMID 20159941 DOI: 10.1124/mol.109.061804  1
2010 Hein P, von Zastrow M. Membrane traffic in the post-genomic era Genome Biology. 11. DOI: 10.1186/gb-2010-11-5-119  1
2010 Tanowitz M, von Zastrow M. Agonist-induced desensitization and endocytosis of g-protein-coupled receptors Handbook of Cell Signaling, 2/E. 1: 177-183. DOI: 10.1016/B978-0-12-374145-5.00027-9  1
2009 Kang DS, Kern RC, Puthenveedu MA, von Zastrow M, Williams JC, Benovic JL. Structure of an arrestin2-clathrin complex reveals a novel clathrin binding domain that modulates receptor trafficking. The Journal of Biological Chemistry. 284: 29860-72. PMID 19710023 DOI: 10.1074/jbc.M109.023366  1
2009 Sorkin A, von Zastrow M. Endocytosis and signalling: intertwining molecular networks. Nature Reviews. Molecular Cell Biology. 10: 609-22. PMID 19696798 DOI: 10.1038/nrm2748  1
2009 Hislop JN, Henry AG, Marchese A, von Zastrow M. Ubiquitination regulates proteolytic processing of G protein-coupled receptors after their sorting to lysosomes. The Journal of Biological Chemistry. 284: 19361-70. PMID 19433584 DOI: 10.1074/jbc.M109.001644  1
2009 Yudowski GA, Puthenveedu MA, Henry AG, von Zastrow M. Cargo-mediated regulation of a rapid Rab4-dependent recycling pathway. Molecular Biology of the Cell. 20: 2774-84. PMID 19369423 DOI: 10.1091/mbc.E08-08-0892  1
2009 Yu YJ, Arttamangkul S, Evans CJ, Williams JT, von Zastrow M. Neurokinin 1 receptors regulate morphine-induced endocytosis and desensitization of mu-opioid receptors in CNS neurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 29: 222-33. PMID 19129399 DOI: 10.1523/JNEUROSCI.4315-08.2009  1
2009 Lauffer BE, Chen S, Melero C, Kortemme T, von Zastrow M, Vargas GA. Engineered protein connectivity to actin mimics PDZ-dependent recycling of G protein-coupled receptors but not its regulation by Hrs. The Journal of Biological Chemistry. 284: 2448-58. PMID 19001361 DOI: 10.1074/jbc.M806370200  1
2008 Tanowitz M, Hislop JN, von Zastrow M. Alternative splicing determines the post-endocytic sorting fate of G-protein-coupled receptors. The Journal of Biological Chemistry. 283: 35614-21. PMID 18936093 DOI: 10.1074/jbc.M806588200  1
2008 Arttamangkul S, Quillinan N, Low MJ, von Zastrow M, Pintar J, Williams JT. Differential activation and trafficking of micro-opioid receptors in brain slices. Molecular Pharmacology. 74: 972-9. PMID 18612077 DOI: 10.1124/mol.108.048512  1
2008 N'Diaye EN, Hanyaloglu AC, Kajihara KK, Puthenveedu MA, Wu P, von Zastrow M, Brown EJ. The ubiquitin-like protein PLIC-2 is a negative regulator of G protein-coupled receptor endocytosis. Molecular Biology of the Cell. 19: 1252-60. PMID 18199683 DOI: 10.1091/mbc.E07-08-0775  1
2008 Hanyaloglu AC, von Zastrow M. Regulation of GPCRs by endocytic membrane trafficking and its potential implications. Annual Review of Pharmacology and Toxicology. 48: 537-68. PMID 18184106 DOI: 10.1146/annurev.pharmtox.48.113006.094830  1
2008 Shaw RM, Fay AJ, Puthenveedu MA, von Zastrow M, Jan YN, Jan LY. Microtubule Plus-End-Tracking Proteins Target Gap Junctions Directly from the Cell Interior to Adherens Junctions (DOI:10.1016/j.cell.2006.12.037) Cell. 133: 376. DOI: 10.1016/j.cell.2008.03.023  1
2007 Yudowski GA, Puthenveedu MA, Leonoudakis D, Panicker S, Thorn KS, Beattie EC, von Zastrow M. Real-time imaging of discrete exocytic events mediating surface delivery of AMPA receptors. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 27: 11112-21. PMID 17928453 DOI: 10.1523/JNEUROSCI.2465-07.2007  1
2007 Puthenveedu MA, Yudowski GA, von Zastrow M. Endocytosis of neurotransmitter receptors: location matters. Cell. 130: 988-9. PMID 17889644 DOI: 10.1016/j.cell.2007.09.006  1
2007 von Zastrow M, Sorkin A. Signaling on the endocytic pathway. Current Opinion in Cell Biology. 19: 436-45. PMID 17662591 DOI: 10.1016/j.ceb.2007.04.021  1
2007 Wang Y, Lauffer B, Von Zastrow M, Kobilka BK, Xiang Y. N-ethylmaleimide-sensitive factor regulates beta2 adrenoceptor trafficking and signaling in cardiomyocytes. Molecular Pharmacology. 72: 429-39. PMID 17510209 DOI: 10.1124/mol.107.037747  1
2007 Shaw RM, Fay AJ, Puthenveedu MA, von Zastrow M, Jan YN, Jan LY. Microtubule plus-end-tracking proteins target gap junctions directly from the cell interior to adherens junctions. Cell. 128: 547-60. PMID 17289573 DOI: 10.1016/j.cell.2006.12.037  1
2007 Hanyaloglu AC, von Zastrow M. A novel sorting sequence in the beta2-adrenergic receptor switches recycling from default to the Hrs-dependent mechanism. The Journal of Biological Chemistry. 282: 3095-104. PMID 17138565 DOI: 10.1074/jbc.M605398200  1
2007 Urban JD, Clarke WP, von Zastrow M, Nichols DE, Kobilka B, Weinstein H, Javitch JA, Roth BL, Christopoulos A, Sexton PM, Miller KJ, Spedding M, Mailman RB. Functional selectivity and classical concepts of quantitative pharmacology. The Journal of Pharmacology and Experimental Therapeutics. 320: 1-13. PMID 16803859 DOI: 10.1124/jpet.106.104463  1
2007 Urban JD, Vargas GA, von Zastrow M, Mailman RB. Aripiprazole has functionally selective actions at dopamine D2 receptor-mediated signaling pathways. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 32: 67-77. PMID 16554739 DOI: 10.1038/sj.npp.1301071  1
2006 Puthenveedu MA, von Zastrow M. Cargo regulates clathrin-coated pit dynamics. Cell. 127: 113-24. PMID 17018281 DOI: 10.1016/j.cell.2006.08.035  1
2006 Yudowski GA, Puthenveedu MA, von Zastrow M. Distinct modes of regulated receptor insertion to the somatodendritic plasma membrane. Nature Neuroscience. 9: 622-7. PMID 16604070 DOI: 10.1038/nn1679  1
2005 Haberstock-Debic H, Kim KA, Yu YJ, von Zastrow M. Morphine promotes rapid, arrestin-dependent endocytosis of mu-opioid receptors in striatal neurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 25: 7847-57. PMID 16120787 DOI: 10.1523/JNEUROSCI.5045-04.2005  1
2005 Hanyaloglu AC, McCullagh E, von Zastrow M. Essential role of Hrs in a recycling mechanism mediating functional resensitization of cell signaling. The Embo Journal. 24: 2265-83. PMID 15944737 DOI: 10.1038/sj.emboj.7600688  1
2005 Trester-Zedlitz M, Burlingame A, Kobilka B, von Zastrow M. Mass spectrometric analysis of agonist effects on posttranslational modifications of the beta-2 adrenoceptor in mammalian cells. Biochemistry. 44: 6133-43. PMID 15835901 DOI: 10.1021/bi0475469  1
2005 Gage RM, Matveeva EA, Whiteheart SW, von Zastrow M. Type I PDZ ligands are sufficient to promote rapid recycling of G Protein-coupled receptors independent of binding to N-ethylmaleimide-sensitive factor. The Journal of Biological Chemistry. 280: 3305-13. PMID 15548537 DOI: 10.1074/jbc.M406934200  0.32
2005 Cao TT, Brelot A, von Zastrow M. The composition of the beta-2 adrenergic receptor oligomer affects its membrane trafficking after ligand-induced endocytosis. Molecular Pharmacology. 67: 288-97. PMID 15492118 DOI: 10.1124/mol.104.003608  1
2004 von Zastrow M. A cell biologist's perspective on physiological adaptation to opiate drugs. Neuropharmacology. 47: 286-92. PMID 15464144 DOI: 10.1016/j.neuropharm.2004.05.007  1
2004 Tanowitz M, von Zastrow M. Identification of protein interactions by yeast two-hybrid screening and coimmunoprecipitation. Methods in Molecular Biology (Clifton, N.J.). 259: 353-69. PMID 15250504 DOI: 10.1385/1-59259-754-8:353  1
2004 Vargas GA, Von Zastrow M. Identification of a novel endocytic recycling signal in the D1 dopamine receptor. The Journal of Biological Chemistry. 279: 37461-9. PMID 15192107 DOI: 10.1074/jbc.M401034200  1
2004 Hislop JN, Marley A, Von Zastrow M. Role of mammalian vacuolar protein-sorting proteins in endocytic trafficking of a non-ubiquitinated G protein-coupled receptor to lysosomes. The Journal of Biological Chemistry. 279: 22522-31. PMID 15024011 DOI: 10.1074/jbc.M311062200  1
2004 von Zastrow M. Opioid receptor regulation. Neuromolecular Medicine. 5: 51-8. PMID 15001812 DOI: 10.1385/NMM:5:1:051  1
2003 von Zastrow M. Mechanisms regulating membrane trafficking of G protein-coupled receptors in the endocytic pathway. Life Sciences. 74: 217-24. PMID 14607249 DOI: 10.1016/j.lfs.2003.09.008  1
2003 Tanowitz M, von Zastrow M. A novel endocytic recycling signal that distinguishes the membrane trafficking of naturally occurring opioid receptors. The Journal of Biological Chemistry. 278: 45978-86. PMID 12939277 DOI: 10.1074/jbc.M304504200  1
2003 von Zastrow M, Svingos A, Haberstock-Debic H, Evans C. Regulated endocytosis of opioid receptors: cellular mechanisms and proposed roles in physiological adaptation to opiate drugs. Current Opinion in Neurobiology. 13: 348-53. PMID 12850220 DOI: 10.1016/S0959-4388(03)00069-2  1
2003 Elenko E, Fischer T, Niesman I, Harding T, McQuistan T, Von Zastrow M, Farquhar MG. Spatial regulation of Galphai protein signaling in clathrin-coated membrane microdomains containing GAIP. Molecular Pharmacology. 64: 11-20. PMID 12815156 DOI: 10.1124/mol.64.1.11  1
2003 Haberstock-Debic H, Wein M, Barrot M, Colago EE, Rahman Z, Neve RL, Pickel VM, Nestler EJ, von Zastrow M, Svingos AL. Morphine acutely regulates opioid receptor trafficking selectively in dendrites of nucleus accumbens neurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 23: 4324-32. PMID 12764121  1
2003 Kim KA, von Zastrow M. Neurotrophin-regulated sorting of opioid receptors in the biosynthetic pathway of neurosecretory cells. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 23: 2075-85. PMID 12657666  1
2002 Whistler JL, Gerber BO, Meng EC, Baranski TJ, von Zastrow M, Bourne HR. Constitutive activation and endocytosis of the complement factor 5a receptor: evidence for multiple activated conformations of a G protein-coupled receptor. Traffic (Copenhagen, Denmark). 3: 866-77. PMID 12453150 DOI: 10.1034/j.1600-0854.2002.31203.x  1
2002 Tanowitz M, Von Zastrow M. Ubiquitination-independent trafficking of G protein-coupled receptors to lysosomes. The Journal of Biological Chemistry. 277: 50219-22. PMID 12401797 DOI: 10.1074/jbc.C200536200  1
2002 Xia H, von Zastrow M, Malenka RC. A novel anterograde trafficking signal present in the N-terminal extracellular domain of ionotropic glutamate receptors. The Journal of Biological Chemistry. 277: 47765-9. PMID 12368290 DOI: 10.1074/jbc.M207122200  1
2002 Sorkin A, Von Zastrow M. Signal transduction and endocytosis: close encounters of many kinds. Nature Reviews. Molecular Cell Biology. 3: 600-14. PMID 12154371 DOI: 10.1038/nrm883  1
2002 Whistler JL, Enquist J, Marley A, Fong J, Gladher F, Tsuruda P, Murray SR, Von Zastrow M. Modulation of postendocytic sorting of G protein-coupled receptors. Science (New York, N.Y.). 297: 615-20. PMID 12142540 DOI: 10.1126/science.1073308  1
2002 Alvarez VA, Arttamangkul S, Dang V, Salem A, Whistler JL, Von Zastrow M, Grandy DK, Williams JT. mu-Opioid receptors: Ligand-dependent activation of potassium conductance, desensitization, and internalization. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 22: 5769-76. PMID 12097530  1
2002 Beattie EC, Stellwagen D, Morishita W, Bresnahan JC, Ha BK, Von Zastrow M, Beattie MS, Malenka RC. Control of synaptic strength by glial TNFalpha. Science (New York, N.Y.). 295: 2282-5. PMID 11910117 DOI: 10.1126/science.1067859  1
2002 He L, Fong J, von Zastrow M, Whistler JL. Regulation of opioid receptor trafficking and morphine tolerance by receptor oligomerization. Cell. 108: 271-82. PMID 11832216 DOI: 10.1016/S0092-8674(02)00613-X  1
2001 von Zastrow M, Mostov K. Signal transduction. A new thread in an intricate web. Science (New York, N.Y.). 294: 1845-7. PMID 11729293 DOI: 10.1126/science.1067418  1
2001 Kim KA, von Zastrow M. Old drugs learn new tricks: insights from mammalian trace amine receptors. Molecular Pharmacology. 60: 1165-7. PMID 11723221  1
2001 Gage RM, Kim KA, Cao TT, von Zastrow M. A transplantable sorting signal that is sufficient to mediate rapid recycling of G protein-coupled receptors. The Journal of Biological Chemistry. 276: 44712-20. PMID 11560936 DOI: 10.1074/jbc.M107417200  1
2001 von Zastrow M. Role of endocytosis in signalling and regulation of G-protein-coupled receptors. Biochemical Society Transactions. 29: 500-4. PMID 11498017 DOI: 10.1042/BST0290500  1
2001 Whistler JL, Tsao P, von Zastrow M. A phosphorylation-regulated brake mechanism controls the initial endocytosis of opioid receptors but is not required for post-endocytic sorting to lysosomes. The Journal of Biological Chemistry. 276: 34331-8. PMID 11443128 DOI: 10.1074/jbc.M104627200  1
2001 Carroll RC, Beattie EC, von Zastrow M, Malenka RC. Role of AMPA receptor endocytosis in synaptic plasticity. Nature Reviews. Neuroscience. 2: 315-24. PMID 11331915 DOI: 10.1038/35072500  1
2001 von Zastrow M. Endocytosis and downregulation of G protein-coupled receptors. Parkinsonism & Related Disorders. 7: 265-271. PMID 11331198 DOI: 10.1016/S1353-8020(00)00069-9  1
2001 Tsao PI, von Zastrow M. Diversity and specificity in the regulated endocytic membrane trafficking of G-protein-coupled receptors. Pharmacology & Therapeutics. 89: 139-47. PMID 11316517 DOI: 10.1016/S0163-7258(00)00107-8  1
2001 Klein U, Müller C, Chu P, Birnbaumer M, von Zastrow M. Heterologous inhibition of G protein-coupled receptor endocytosis mediated by receptor-specific trafficking of beta-arrestins. The Journal of Biological Chemistry. 276: 17442-7. PMID 11278476 DOI: 10.1074/jbc.M009214200  1
2001 Tsao P, Cao T, von Zastrow M. Role of endocytosis in mediating downregulation of G-protein-coupled receptors. Trends in Pharmacological Sciences. 22: 91-6. PMID 11166853 DOI: 10.1016/S0165-6147(00)01620-5  1
2000 Whistler J, Beattie E, von Zastrow M. Tales from the crypt: evidence for heptahelical receptor signaling in the endocytic pathway. Science's Stke : Signal Transduction Knowledge Environment. 2000: pe1. PMID 11752604 DOI: 10.1126/stke.2000.47.pe1  1
2000 Beattie EC, Carroll RC, Yu X, Morishita W, Yasuda H, von Zastrow M, Malenka RC. Regulation of AMPA receptor endocytosis by a signaling mechanism shared with LTD. Nature Neuroscience. 3: 1291-300. PMID 11100150 DOI: 10.1038/81823  1
2000 Tsao P, von Zastrow M. Downregulation of G protein-coupled receptors. Current Opinion in Neurobiology. 10: 365-9. PMID 10851176 DOI: 10.1016/S0959-4388(00)00096-9  1
2000 Tsao PI, von Zastrow M. Type-specific sorting of G protein-coupled receptors after endocytosis. The Journal of Biological Chemistry. 275: 11130-40. PMID 10753919 DOI: 10.1074/jbc.275.15.11130  1
1999 Lüscher C, Xia H, Beattie EC, Carroll RC, von Zastrow M, Malenka RC, Nicoll RA. Role of AMPA receptor cycling in synaptic transmission and plasticity. Neuron. 24: 649-58. PMID 10595516  1
1999 Carroll RC, Beattie EC, Xia H, Lüscher C, Altschuler Y, Nicoll RA, Malenka RC, von Zastrow M. Dynamin-dependent endocytosis of ionotropic glutamate receptors. Proceedings of the National Academy of Sciences of the United States of America. 96: 14112-7. PMID 10570207 DOI: 10.1073/pnas.96.24.14112  1
1999 Cao TT, Deacon HW, Reczek D, Bretscher A, von Zastrow M. A kinase-regulated PDZ-domain interaction controls endocytic sorting of the beta2-adrenergic receptor. Nature. 401: 286-90. PMID 10499588 DOI: 10.1038/45816  1
1999 Whistler JL, Chuang HH, Chu P, Jan LY, von Zastrow M. Functional dissociation of mu opioid receptor signaling and endocytosis: implications for the biology of opiate tolerance and addiction. Neuron. 23: 737-46. PMID 10482240 DOI: 10.1016/S0896-6273(01)80032-5  1
1999 Whistler JL, von Zastrow M. Dissociation of functional roles of dynamin in receptor-mediated endocytosis and mitogenic signal transduction. The Journal of Biological Chemistry. 274: 24575-8. PMID 10455121 DOI: 10.1074/jbc.274.35.24575  1
1999 Lissin DV, Malenka RC, Von Zastrow M. An immunocytochemical assay for activity-dependent redistribution of glutamate receptors from the postsynaptic plasma membrane. Annals of the New York Academy of Sciences. 868: 550-3. PMID 10414334 DOI: 10.1111/j.1749-6632.1999.tb11326.x  1
1999 Carroll RC, Lissin DV, von Zastrow M, Nicoll RA, Malenka RC. Rapid redistribution of glutamate receptors contributes to long-term depression in hippocampal cultures. Nature Neuroscience. 2: 454-60. PMID 10321250 DOI: 10.1038/8123  1
1999 Lissin DV, Carroll RC, Nicoll RA, Malenka RC, von Zastrow M. Rapid, activation-induced redistribution of ionotropic glutamate receptors in cultured hippocampal neurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 19: 1263-72. PMID 9952404  1
1999 Vickery RG, von Zastrow M. Distinct dynamin-dependent and -independent mechanisms target structurally homologous dopamine receptors to different endocytic membranes. The Journal of Cell Biology. 144: 31-43. PMID 9885242 DOI: 10.1083/jcb.144.1.31  1
1999 Von Zastrow M. Endocytic membrane trafficking of g protein-coupled receptors Proceedings of the Western Pharmacology Society. 42: 135.  1
1998 Oldenhof J, Vickery R, Anafi M, Oak J, Ray A, Schoots O, Pawson T, von Zastrow M, Van Tol HH. SH3 binding domains in the dopamine D4 receptor. Biochemistry. 37: 15726-36. PMID 9843378 DOI: 10.1021/bi981634+  1
1998 Murray SR, Evans CJ, von Zastrow M. Phosphorylation is not required for dynamin-dependent endocytosis of a truncated mutant opioid receptor. The Journal of Biological Chemistry. 273: 24987-91. PMID 9737953 DOI: 10.1074/jbc.273.39.24987  1
1998 Cao TT, Mays RW, von Zastrow M. Regulated endocytosis of G-protein-coupled receptors by a biochemically and functionally distinct subpopulation of clathrin-coated pits. The Journal of Biological Chemistry. 273: 24592-602. PMID 9733754 DOI: 10.1074/jbc.273.38.24592  1
1998 Whistler JL, von Zastrow M. Morphine-activated opioid receptors elude desensitization by beta-arrestin. Proceedings of the National Academy of Sciences of the United States of America. 95: 9914-9. PMID 9707575 DOI: 10.1073/pnas.95.17.9914  1
1998 Lissin DV, Gomperts SN, Carroll RC, Christine CW, Kalman D, Kitamura M, Hardy S, Nicoll RA, Malenka RC, von Zastrow M. Activity differentially regulates the surface expression of synaptic AMPA and NMDA glutamate receptors. Proceedings of the National Academy of Sciences of the United States of America. 95: 7097-102. PMID 9618545 DOI: 10.1073/pnas.95.12.7097  1
1998 Keith DE, Anton B, Murray SR, Zaki PA, Chu PC, Lissin DV, Monteillet-Agius G, Stewart PL, Evans CJ, von Zastrow M. mu-Opioid receptor internalization: opiate drugs have differential effects on a conserved endocytic mechanism in vitro and in the mammalian brain. Molecular Pharmacology. 53: 377-84. PMID 9495801  1
1997 Chu P, Murray S, Lissin D, von Zastrow M. Delta and kappa opioid receptors are differentially regulated by dynamin-dependent endocytosis when activated by the same alkaloid agonist. The Journal of Biological Chemistry. 272: 27124-30. PMID 9341153 DOI: 10.1074/jbc.272.43.27124  1
1997 Klein U, Ramirez MT, Kobilka BK, von Zastrow M. A novel interaction between adrenergic receptors and the alpha-subunit of eukaryotic initiation factor 2B. The Journal of Biological Chemistry. 272: 19099-102. PMID 9235896 DOI: 10.1074/jbc.272.31.19099  1
1996 Mostafapour S, Kobilka BK, von Zastrow M. Pharmacological sequestration of a chimeric beta 3/beta 2 adrenergic receptor occurs without a corresponding amount of receptor internalization. Receptors & Signal Transduction. 6: 151-63. PMID 9259050  1
1996 Wedegaertner PB, Bourne HR, von Zastrow M. Activation-induced subcellular redistribution of Gs alpha. Molecular Biology of the Cell. 7: 1225-33. PMID 8856666  1
1996 Sternini C, Spann M, Anton B, Keith DE, Bunnett NW, von Zastrow M, Evans C, Brecha NC. Agonist-selective endocytosis of mu opioid receptor by neurons in vivo. Proceedings of the National Academy of Sciences of the United States of America. 93: 9241-6. PMID 8799185 DOI: 10.1073/pnas.93.17.9241  1
1996 Keith DE, Murray SR, Zaki PA, Chu PC, Lissin DV, Kang L, Evans CJ, von Zastrow M. Morphine activates opioid receptors without causing their rapid internalization. The Journal of Biological Chemistry. 271: 19021-4. PMID 8702570 DOI: 10.1074/jbc.271.32.19021  1
1994 von Zastrow M, Kobilka BK. Antagonist-dependent and -independent steps in the mechanism of adrenergic receptor internalization. The Journal of Biological Chemistry. 269: 18448-52. PMID 7518433  1
1994 von Zastrow M, Keith D, Zaki P, Evans C. Intracellular trafficking of epitope-tagged opioid receptors: Different effects of morphine and enkephalin Regulatory Peptides. 54: 315-316. DOI: 10.1016/0167-0115(94)90516-9  1
1993 Von Zastrow M, Keith DE, Evans CJ. Agonist-induced state of the delta-opioid receptor that discriminates between opioid peptides and opiate alkaloids. Molecular Pharmacology. 44: 166-72. PMID 8393518  1
1993 von Zastrow M, Link R, Daunt D, Barsh G, Kobilka B. Subtype-specific differences in the intracellular sorting of G protein-coupled receptors. The Journal of Biological Chemistry. 268: 763-6. PMID 7678260  1
1992 von Zastrow M, Kobilka BK. Ligand-regulated internalization and recycling of human beta 2-adrenergic receptors between the plasma membrane and endosomes containing transferrin receptors. The Journal of Biological Chemistry. 267: 3530-8. PMID 1371121  1
1992 Campanelli JT, Ferns M, Hoch W, Rupp F, von Zastrow M, Hall Z, Scheller RH. Agrin: a synaptic basal lamina protein that regulates development of the neuromuscular junction. Cold Spring Harbor Symposia On Quantitative Biology. 57: 461-72. PMID 1339682  1
1992 Suryanarayana S, von Zastrow M, Kobilka BK. Identification of intramolecular interactions in adrenergic receptors. The Journal of Biological Chemistry. 267: 21991-4. PMID 1331041  1
1991 Suryanarayana S, Daunt DA, Von Zastrow M, Kobilka BK. A single point mutation in the seventh hydrophobic domain of the alpha 2-adrenergic receptor changes antagonist binding specificity to that of a beta receptor. Transactions of the Association of American Physicians. 104: 62-8. PMID 1688262  1
1991 Suryanarayana S, Daunt DA, Von Zastrow M, Kobilka BK. A point mutation in the seventh hydrophobic domain of the alpha 2 adrenergic receptor increases its affinity for a family of beta receptor antagonists. The Journal of Biological Chemistry. 266: 15488-92. PMID 1678390  1
1990 Van Gelder RN, von Zastrow ME, Yool A, Dement WC, Barchas JD, Eberwine JH. Amplified RNA synthesized from limited quantities of heterogeneous cDNA. Proceedings of the National Academy of Sciences of the United States of America. 87: 1663-7. PMID 1689846  1
1990 Von Zastrow M, Evans CJ. Morphine blocks the peptide-selective opioid binding change without blocking receptor downregulation New Leads in Opioid Research: Proceedings of the International Narcotics Research Conference. Ics914. 101-102.  1
1990 Evans CJ, Von Zastrow M. A state of the delta opioid receptor that is 'blind' to opioid peptides yet retains high affinity for the opiate alkaloids New Leads in Opioid Research: Proceedings of the International Narcotics Research Conference. Ics914. 159-160.  1
1989 von Zastrow M, Castle AM, Castle JD. Ammonium chloride alters secretory protein sorting within the maturing exocrine storage compartment. The Journal of Biological Chemistry. 264: 6566-71. PMID 2467913  1
1987 von Zastrow M, Castle JD. Protein sorting among two distinct export pathways occurs from the content of maturing exocrine storage granules. The Journal of Cell Biology. 105: 2675-84. PMID 3500952  1
1987 Castle JD, Cameron RS, Arvan P, von Zastrow M, Rudnick G. Similarities and differences among neuroendocrine, exocrine, and endocytic vesicles. Annals of the New York Academy of Sciences. 493: 448-60. PMID 3296913  1
1986 von Zastrow M, Tritton TR, Castle JD. Exocrine secretion granules contain peptide amidation activity. Proceedings of the National Academy of Sciences of the United States of America. 83: 3297-301. PMID 3458183  1
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