Mark von Zastrow - Publications

Affiliations: 
University of California, San Francisco, San Francisco, CA 

112 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Tsvetanova NG, Trester-Zedlitz M, Newton BW, Peng GE, Johnson JR, Jimenez-Morales D, Kurland AP, Krogan NJ, von Zastrow M. Endosomal cAMP production broadly impacts the cellular phosphoproteome. The Journal of Biological Chemistry. 100907. PMID 34166681 DOI: 10.1016/j.jbc.2021.100907  0.396
2021 Peng GE, Pessino V, Huang B, von Zastrow M. Spatial decoding of endosomal cAMP signals by a metastable cytoplasmic PKA network. Nature Chemical Biology. PMID 33649598 DOI: 10.1038/s41589-021-00747-0  0.417
2021 von Zastrow M, Sorkin A. Mechanisms for Regulating and Organizing Receptor Signaling by Endocytosis. Annual Review of Biochemistry. PMID 33606955 DOI: 10.1146/annurev-biochem-081820-092427  0.513
2020 Semesta KM, Tian R, Kampmann M, von Zastrow M, Tsvetanova NG. A high-throughput CRISPR interference screen for dissecting functional regulators of GPCR/cAMP signaling. Plos Genetics. 16: e1009103. PMID 33052901 DOI: 10.1371/journal.pgen.1009103  0.331
2020 Lazar AM, Irannejad R, Baldwin TA, Sundaram AB, Gutkind JS, Inoue A, Dessauer CW, Von Zastrow M. G protein-regulated endocytic trafficking of adenylyl cyclase type 9. Elife. 9. PMID 32515353 DOI: 10.7554/Elife.58039  0.399
2020 Stoeber M, Jullié D, Li J, Chakraborty S, Majumdar S, Lambert NA, Manglik A, von Zastrow M. Agonist-selective recruitment of engineered protein probes and of GRK2 by opioid receptors in living cells. Elife. 9. PMID 32096468 DOI: 10.7554/Elife.54208  0.868
2019 Jullié D, Stoeber M, Sibarita JB, Zieger HL, Bartol TM, Arttamangkul S, Sejnowski TJ, Hosy E, von Zastrow M. A Discrete Presynaptic Vesicle Cycle for Neuromodulator Receptors. Neuron. PMID 31837915 DOI: 10.1016/J.Neuron.2019.11.016  0.852
2018 Lobingier BT, von Zastrow M. When trafficking and signaling mix: how subcellular location shapes GPCR activation of heterotrimeric G proteins. Traffic (Copenhagen, Denmark). PMID 30578610 DOI: 10.1111/Tra.12634  0.839
2018 Stoeber M, Jullié D, Lobingier BT, Laeremans T, Steyaert J, Schiller PW, Manglik A, von Zastrow M. A Genetically Encoded Biosensor Reveals Location Bias of Opioid Drug Action. Neuron. PMID 29754753 DOI: 10.1016/J.Neuron.2018.04.021  0.787
2018 Eichel K, Jullié D, Barsi-Rhyne B, Latorraca NR, Masureel M, Sibarita JB, Dror RO, von Zastrow M. Catalytic activation of β-arrestin by GPCRs. Nature. PMID 29720660 DOI: 10.1038/S41586-018-0079-1  0.79
2017 O'Hayre M, Eichel K, Avino S, Zhao X, Steffen DJ, Feng X, Kawakami K, Aoki J, Messer K, Sunahara R, Inoue A, von Zastrow M, Gutkind JS. Genetic evidence that β-arrestins are dispensable for the initiation of β2-adrenergic receptor signaling to ERK. Science Signaling. 10. PMID 28634209 DOI: 10.1126/Scisignal.Aal3395  0.308
2017 Irannejad R, Pessino V, Mika D, Huang B, Wedegaertner PB, Conti M, von Zastrow M. Functional selectivity of GPCR-directed drug action through location bias. Nature Chemical Biology. PMID 28553949 DOI: 10.1038/Nchembio.2389  0.534
2017 Lobingier BT, Hüttenhain R, Eichel K, Miller KB, Ting AY, von Zastrow M, Krogan NJ. An Approach to Spatiotemporally Resolve Protein Interaction Networks in Living Cells. Cell. 169: 350-360.e12. PMID 28388416 DOI: 10.1016/J.Cell.2017.03.022  0.794
2017 Uchida Y, Rutaganira FU, Jullié D, Shokat KM, von Zastrow M. Endosomal Phosphatidylinositol 3-Kinase Is Essential for Canonical GPCR Signaling. Molecular Pharmacology. 91: 65-73. PMID 27821547 DOI: 10.1124/Mol.116.106252  0.836
2016 Tsvetanova NG, Trester-Zedlitz M, Newton BW, Riordan DP, Sundaram AB, Johnson JR, Krogan NJ, von Zastrow M. GPCR endocytosis confers uniformity in responses to chemically distinct ligands. Molecular Pharmacology. PMID 27879340 DOI: 10.1124/Mol.116.106369  0.328
2016 Gupta V, Bhandari D, Leyme A, Aznar N, Midde KK, Lo IC, Ear J, Niesman I, López-Sánchez I, Blanco-Canosa JB, von Zastrow M, Garcia-Marcos M, Farquhar MG, Ghosh P. GIV/Girdin activates Gαi and inhibits Gαs via the same motif. Proceedings of the National Academy of Sciences of the United States of America. PMID 27621449 DOI: 10.1073/pnas.1609502113  0.357
2016 Gendron L, Cahill CM, von Zastrow M, Schiller PW, Pineyro G. Molecular Pharmacology of δ-Opioid Receptors. Pharmacological Reviews. 68: 631-700. PMID 27343248 DOI: 10.1124/Pr.114.008979  0.341
2016 Tian X, Irannejad R, Bowman SL, Du Y, Puthenveedu MA, von Zastrow M, Benovic JL. The α-Arrestin ARRDC3 Regulates the Endosomal Residence Time and Intracellular Signaling of the β2-Adrenergic Receptor. The Journal of Biological Chemistry. PMID 27226565 DOI: 10.1074/Jbc.M116.716589  0.782
2015 Irannejad R, Tsvetanova NG, Lobingier BT, von Zastrow M. Effects of endocytosis on receptor-mediated signaling. Current Opinion in Cell Biology. 35: 137-43. PMID 26057614 DOI: 10.1016/J.Ceb.2015.05.005  0.828
2015 Koliwer J, Park M, Bauch C, von Zastrow M, Kreienkamp HJ. The golgi-associated PDZ domain protein PIST/GOPC stabilizes the β1-adrenergic receptor in intracellular compartments after internalization. The Journal of Biological Chemistry. 290: 6120-9. PMID 25614626 DOI: 10.1074/jbc.M114.605725  0.579
2014 Choy RW, Park M, Temkin P, Herring BE, Marley A, Nicoll RA, von Zastrow M. Retromer mediates a discrete route of local membrane delivery to dendrites. Neuron. 82: 55-62. PMID 24698268 DOI: 10.1016/J.Neuron.2014.02.018  0.853
2014 Irannejad R, Kotowski SJ, von Zastrow M. Investigating signaling consequences of GPCR trafficking in the endocytic pathway. Methods in Enzymology. 535: 403-18. PMID 24377936 DOI: 10.1016/B978-0-12-397925-4.00023-7  0.817
2013 Irannejad R, Tomshine JC, Tomshine JR, Chevalier M, Mahoney JP, Steyaert J, Rasmussen SG, Sunahara RK, El-Samad H, Huang B, von Zastrow M. Conformational biosensors reveal GPCR signalling from endosomes. Nature. 495: 534-8. PMID 23515162 DOI: 10.1038/Nature12000  0.498
2013 Williams JT, Ingram SL, Henderson G, Chavkin C, von Zastrow M, Schulz S, Koch T, Evans CJ, Christie MJ. Regulation of μ-opioid receptors: desensitization, phosphorylation, internalization, and tolerance. Pharmacological Reviews. 65: 223-54. PMID 23321159 DOI: 10.1124/Pr.112.005942  0.365
2013 Just S, Illing S, Trester-Zedlitz M, Lau EK, Kotowski SJ, Miess E, Mann A, Doll C, Trinidad JC, Burlingame AL, von Zastrow M, Schulz S. Differentiation of opioid drug effects by hierarchical multi-site phosphorylation. Molecular Pharmacology. 83: 633-9. PMID 23239825 DOI: 10.1124/Mol.112.082875  0.754
2012 von Zastrow M, Williams JT. Modulating neuromodulation by receptor membrane traffic in the endocytic pathway. Neuron. 76: 22-32. PMID 23040804 DOI: 10.1016/j.neuron.2012.09.022  0.565
2012 Henry AG, Hislop JN, Grove J, Thorn K, Marsh M, von Zastrow M. Regulation of endocytic clathrin dynamics by cargo ubiquitination. Developmental Cell. 23: 519-32. PMID 22940114 DOI: 10.1016/J.Devcel.2012.08.003  0.835
2012 Avasthi P, Marley A, Lin H, Gregori-Puigjane E, Shoichet BK, von Zastrow M, Marshall WF. A chemical screen identifies class a g-protein coupled receptors as regulators of cilia. Acs Chemical Biology. 7: 911-9. PMID 22375814 DOI: 10.1021/Cb200349V  0.39
2011 Hislop JN, Henry AG, von Zastrow M. Ubiquitination in the first cytoplasmic loop of μ-opioid receptors reveals a hierarchical mechanism of lysosomal down-regulation. The Journal of Biological Chemistry. 286: 40193-204. PMID 21953467 DOI: 10.1074/Jbc.M111.288555  0.817
2011 Romero G, von Zastrow M, Friedman PA. Role of PDZ proteins in regulating trafficking, signaling, and function of GPCRs: means, motif, and opportunity. Advances in Pharmacology (San Diego, Calif.). 62: 279-314. PMID 21907913 DOI: 10.1016/B978-0-12-385952-5.00003-8  0.428
2011 Yudowski GA, von Zastrow M. Investigating G protein-coupled receptor endocytosis and trafficking by TIR-FM. Methods in Molecular Biology (Clifton, N.J.). 756: 325-32. PMID 21870236 DOI: 10.1007/978-1-61779-160-4_19  0.847
2011 Lau EK, Trester-Zedlitz M, Trinidad JC, Kotowski SJ, Krutchinsky AN, Burlingame AL, von Zastrow M. Quantitative encoding of the effect of a partial agonist on individual opioid receptors by multisite phosphorylation and threshold detection. Science Signaling. 4: ra52. PMID 21868358 DOI: 10.1126/Scisignal.2001748  0.8
2011 Kotowski SJ, Hopf FW, Seif T, Bonci A, von Zastrow M. Endocytosis promotes rapid dopaminergic signaling. Neuron. 71: 278-90. PMID 21791287 DOI: 10.1016/J.Neuron.2011.05.036  0.82
2011 Temkin P, Lauffer B, Jäger S, Cimermancic P, Krogan NJ, von Zastrow M. SNX27 mediates retromer tubule entry and endosome-to-plasma membrane trafficking of signalling receptors. Nature Cell Biology. 13: 715-21. PMID 21602791 DOI: 10.1038/Ncb2252  0.873
2011 Quillinan N, Lau EK, Virk M, von Zastrow M, Williams JT. Recovery from mu-opioid receptor desensitization after chronic treatment with morphine and methadone. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 31: 4434-43. PMID 21430144 DOI: 10.1523/JNEUROSCI.4874-10.2011  0.355
2011 Henry AG, White IJ, Marsh M, von Zastrow M, Hislop JN. The role of ubiquitination in lysosomal trafficking of δ-opioid receptors. Traffic (Copenhagen, Denmark). 12: 170-84. PMID 21106040 DOI: 10.1111/J.1600-0854.2010.01145.X  0.842
2010 Puthenveedu MA, Lauffer B, Temkin P, Vistein R, Carlton P, Thorn K, Taunton J, Weiner OD, Parton RG, von Zastrow M. Sequence-dependent sorting of recycling proteins by actin-stabilized endosomal microdomains. Cell. 143: 761-73. PMID 21111236 DOI: 10.1016/J.Cell.2010.10.003  0.837
2010 Tzingounis AV, von Zastrow M, Yudowski GA. {Beta}-blocker drugs mediate calcium signaling in native central nervous system neurons by {beta}-arrestin-biased agonism. Proceedings of the National Academy of Sciences of the United States of America. 107: 21028-33. PMID 21078978 DOI: 10.1073/Pnas.1004169107  0.812
2010 Yu YJ, Dhavan R, Chevalier MW, Yudowski GA, von Zastrow M. Rapid delivery of internalized signaling receptors to the somatodendritic surface by sequence-specific local insertion. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 30: 11703-14. PMID 20810891 DOI: 10.1523/Jneurosci.6282-09.2010  0.866
2010 Lauffer BE, Melero C, Temkin P, Lei C, Hong W, Kortemme T, von Zastrow M. SNX27 mediates PDZ-directed sorting from endosomes to the plasma membrane. The Journal of Cell Biology. 190: 565-74. PMID 20733053 DOI: 10.1083/Jcb.201004060  0.81
2010 Hein P, von Zastrow M. Membrane traffic in the post-genomic era Genome Biology. 11. DOI: 10.1186/gb-2010-11-5-119  0.455
2010 Tanowitz M, von Zastrow M. Agonist-induced desensitization and endocytosis of g-protein-coupled receptors Handbook of Cell Signaling, 2/E. 1: 177-183. DOI: 10.1016/B978-0-12-374145-5.00027-9  0.487
2009 Kang DS, Kern RC, Puthenveedu MA, von Zastrow M, Williams JC, Benovic JL. Structure of an arrestin2-clathrin complex reveals a novel clathrin binding domain that modulates receptor trafficking. The Journal of Biological Chemistry. 284: 29860-72. PMID 19710023 DOI: 10.1074/Jbc.M109.023366  0.736
2009 Sorkin A, von Zastrow M. Endocytosis and signalling: intertwining molecular networks. Nature Reviews. Molecular Cell Biology. 10: 609-22. PMID 19696798 DOI: 10.1038/Nrm2748  0.475
2009 Hislop JN, Henry AG, Marchese A, von Zastrow M. Ubiquitination regulates proteolytic processing of G protein-coupled receptors after their sorting to lysosomes. The Journal of Biological Chemistry. 284: 19361-70. PMID 19433584 DOI: 10.1074/Jbc.M109.001644  0.844
2009 Yudowski GA, Puthenveedu MA, Henry AG, von Zastrow M. Cargo-mediated regulation of a rapid Rab4-dependent recycling pathway. Molecular Biology of the Cell. 20: 2774-84. PMID 19369423 DOI: 10.1091/Mbc.E08-08-0892  0.863
2009 Yu YJ, Arttamangkul S, Evans CJ, Williams JT, von Zastrow M. Neurokinin 1 receptors regulate morphine-induced endocytosis and desensitization of mu-opioid receptors in CNS neurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 29: 222-33. PMID 19129399 DOI: 10.1523/Jneurosci.4315-08.2009  0.72
2009 Lauffer BE, Chen S, Melero C, Kortemme T, von Zastrow M, Vargas GA. Engineered protein connectivity to actin mimics PDZ-dependent recycling of G protein-coupled receptors but not its regulation by Hrs. The Journal of Biological Chemistry. 284: 2448-58. PMID 19001361 DOI: 10.1074/Jbc.M806370200  0.87
2008 Tanowitz M, Hislop JN, von Zastrow M. Alternative splicing determines the post-endocytic sorting fate of G-protein-coupled receptors. The Journal of Biological Chemistry. 283: 35614-21. PMID 18936093 DOI: 10.1074/jbc.M806588200  0.55
2008 Arttamangkul S, Quillinan N, Low MJ, von Zastrow M, Pintar J, Williams JT. Differential activation and trafficking of micro-opioid receptors in brain slices. Molecular Pharmacology. 74: 972-9. PMID 18612077 DOI: 10.1124/Mol.108.048512  0.5
2008 N'Diaye EN, Hanyaloglu AC, Kajihara KK, Puthenveedu MA, Wu P, von Zastrow M, Brown EJ. The ubiquitin-like protein PLIC-2 is a negative regulator of G protein-coupled receptor endocytosis. Molecular Biology of the Cell. 19: 1252-60. PMID 18199683 DOI: 10.1091/mbc.E07-08-0775  0.826
2008 Shaw RM, Fay AJ, Puthenveedu MA, von Zastrow M, Jan YN, Jan LY. Microtubule Plus-End-Tracking Proteins Target Gap Junctions Directly from the Cell Interior to Adherens Junctions (DOI:10.1016/j.cell.2006.12.037) Cell. 133: 376. DOI: 10.1016/J.Cell.2008.03.023  0.64
2007 Yudowski GA, Puthenveedu MA, Leonoudakis D, Panicker S, Thorn KS, Beattie EC, von Zastrow M. Real-time imaging of discrete exocytic events mediating surface delivery of AMPA receptors. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 27: 11112-21. PMID 17928453 DOI: 10.1523/Jneurosci.2465-07.2007  0.826
2007 Puthenveedu MA, Yudowski GA, von Zastrow M. Endocytosis of neurotransmitter receptors: location matters. Cell. 130: 988-9. PMID 17889644 DOI: 10.1016/J.Cell.2007.09.006  0.848
2007 von Zastrow M, Sorkin A. Signaling on the endocytic pathway. Current Opinion in Cell Biology. 19: 436-45. PMID 17662591 DOI: 10.1016/J.Ceb.2007.04.021  0.339
2007 Wang Y, Lauffer B, Von Zastrow M, Kobilka BK, Xiang Y. N-ethylmaleimide-sensitive factor regulates beta2 adrenoceptor trafficking and signaling in cardiomyocytes. Molecular Pharmacology. 72: 429-39. PMID 17510209 DOI: 10.1124/Mol.107.037747  0.85
2007 Shaw RM, Fay AJ, Puthenveedu MA, von Zastrow M, Jan YN, Jan LY. Microtubule plus-end-tracking proteins target gap junctions directly from the cell interior to adherens junctions. Cell. 128: 547-60. PMID 17289573 DOI: 10.1016/J.Cell.2006.12.037  0.67
2007 Urban JD, Clarke WP, von Zastrow M, Nichols DE, Kobilka B, Weinstein H, Javitch JA, Roth BL, Christopoulos A, Sexton PM, Miller KJ, Spedding M, Mailman RB. Functional selectivity and classical concepts of quantitative pharmacology. The Journal of Pharmacology and Experimental Therapeutics. 320: 1-13. PMID 16803859 DOI: 10.1124/Jpet.106.104463  0.743
2007 Urban JD, Vargas GA, von Zastrow M, Mailman RB. Aripiprazole has functionally selective actions at dopamine D2 receptor-mediated signaling pathways. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 32: 67-77. PMID 16554739 DOI: 10.1038/Sj.Npp.1301071  0.362
2006 Puthenveedu MA, von Zastrow M. Cargo regulates clathrin-coated pit dynamics. Cell. 127: 113-24. PMID 17018281 DOI: 10.1016/j.cell.2006.08.035  0.76
2006 Yudowski GA, Puthenveedu MA, von Zastrow M. Distinct modes of regulated receptor insertion to the somatodendritic plasma membrane. Nature Neuroscience. 9: 622-7. PMID 16604070 DOI: 10.1038/Nn1679  0.867
2005 Haberstock-Debic H, Kim KA, Yu YJ, von Zastrow M. Morphine promotes rapid, arrestin-dependent endocytosis of mu-opioid receptors in striatal neurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 25: 7847-57. PMID 16120787 DOI: 10.1523/JNEUROSCI.5045-04.2005  0.634
2005 Kenski DM, Zhang C, von Zastrow M, Shokat KM. Chemical genetic engineering of G protein-coupled receptor kinase 2. The Journal of Biological Chemistry. 280: 35051-61. PMID 16081410 DOI: 10.1074/Jbc.M507594200  0.439
2005 Trester-Zedlitz M, Burlingame A, Kobilka B, von Zastrow M. Mass spectrometric analysis of agonist effects on posttranslational modifications of the beta-2 adrenoceptor in mammalian cells. Biochemistry. 44: 6133-43. PMID 15835901 DOI: 10.1021/Bi0475469  0.68
2005 Gage RM, Matveeva EA, Whiteheart SW, von Zastrow M. Type I PDZ ligands are sufficient to promote rapid recycling of G Protein-coupled receptors independent of binding to N-ethylmaleimide-sensitive factor. The Journal of Biological Chemistry. 280: 3305-13. PMID 15548537 DOI: 10.1074/Jbc.M406934200  0.836
2004 Tanowitz M, von Zastrow M. Identification of protein interactions by yeast two-hybrid screening and coimmunoprecipitation. Methods in Molecular Biology (Clifton, N.J.). 259: 353-69. PMID 15250504 DOI: 10.1385/1-59259-754-8:353  0.357
2004 Vargas GA, Von Zastrow M. Identification of a novel endocytic recycling signal in the D1 dopamine receptor. The Journal of Biological Chemistry. 279: 37461-9. PMID 15192107 DOI: 10.1074/jbc.M401034200  0.583
2003 Tanowitz M, von Zastrow M. A novel endocytic recycling signal that distinguishes the membrane trafficking of naturally occurring opioid receptors. The Journal of Biological Chemistry. 278: 45978-86. PMID 12939277 DOI: 10.1074/jbc.M304504200  0.598
2003 von Zastrow M, Svingos A, Haberstock-Debic H, Evans C. Regulated endocytosis of opioid receptors: cellular mechanisms and proposed roles in physiological adaptation to opiate drugs. Current Opinion in Neurobiology. 13: 348-53. PMID 12850220 DOI: 10.1016/S0959-4388(03)00069-2  0.319
2003 Elenko E, Fischer T, Niesman I, Harding T, McQuistan T, Von Zastrow M, Farquhar MG. Spatial regulation of Galphai protein signaling in clathrin-coated membrane microdomains containing GAIP. Molecular Pharmacology. 64: 11-20. PMID 12815156 DOI: 10.1124/Mol.64.1.11  0.405
2003 Haberstock-Debic H, Wein M, Barrot M, Colago EE, Rahman Z, Neve RL, Pickel VM, Nestler EJ, von Zastrow M, Svingos AL. Morphine acutely regulates opioid receptor trafficking selectively in dendrites of nucleus accumbens neurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 23: 4324-32. PMID 12764121 DOI: 10.1523/Jneurosci.23-10-04324.2003  0.346
2003 Kim KA, von Zastrow M. Neurotrophin-regulated sorting of opioid receptors in the biosynthetic pathway of neurosecretory cells. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 23: 2075-85. PMID 12657666  0.456
2002 Whistler JL, Gerber BO, Meng EC, Baranski TJ, von Zastrow M, Bourne HR. Constitutive activation and endocytosis of the complement factor 5a receptor: evidence for multiple activated conformations of a G protein-coupled receptor. Traffic (Copenhagen, Denmark). 3: 866-77. PMID 12453150 DOI: 10.1034/J.1600-0854.2002.31203.X  0.764
2002 Tanowitz M, Von Zastrow M. Ubiquitination-independent trafficking of G protein-coupled receptors to lysosomes. The Journal of Biological Chemistry. 277: 50219-22. PMID 12401797 DOI: 10.1074/jbc.C200536200  0.524
2002 Xia H, von Zastrow M, Malenka RC. A novel anterograde trafficking signal present in the N-terminal extracellular domain of ionotropic glutamate receptors. The Journal of Biological Chemistry. 277: 47765-9. PMID 12368290 DOI: 10.1074/jbc.M207122200  0.725
2002 Sorkin A, Von Zastrow M. Signal transduction and endocytosis: close encounters of many kinds. Nature Reviews. Molecular Cell Biology. 3: 600-14. PMID 12154371 DOI: 10.1038/Nrm883  0.474
2002 Whistler JL, Enquist J, Marley A, Fong J, Gladher F, Tsuruda P, Murray SR, Von Zastrow M. Modulation of postendocytic sorting of G protein-coupled receptors. Science (New York, N.Y.). 297: 615-20. PMID 12142540 DOI: 10.1126/Science.1073308  0.873
2002 Alvarez VA, Arttamangkul S, Dang V, Salem A, Whistler JL, Von Zastrow M, Grandy DK, Williams JT. mu-Opioid receptors: Ligand-dependent activation of potassium conductance, desensitization, and internalization. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 22: 5769-76. PMID 12097530 DOI: 10.1523/Jneurosci.22-13-05769.2002  0.708
2002 Beattie EC, Stellwagen D, Morishita W, Bresnahan JC, Ha BK, Von Zastrow M, Beattie MS, Malenka RC. Control of synaptic strength by glial TNFalpha. Science (New York, N.Y.). 295: 2282-5. PMID 11910117 DOI: 10.1126/Science.1067859  0.503
2002 He L, Fong J, von Zastrow M, Whistler JL. Regulation of opioid receptor trafficking and morphine tolerance by receptor oligomerization. Cell. 108: 271-82. PMID 11832216 DOI: 10.1016/S0092-8674(02)00613-X  0.683
2001 Gage RM, Kim KA, Cao TT, von Zastrow M. A transplantable sorting signal that is sufficient to mediate rapid recycling of G protein-coupled receptors. The Journal of Biological Chemistry. 276: 44712-20. PMID 11560936 DOI: 10.1074/Jbc.M107417200  0.877
2001 Whistler JL, Tsao P, von Zastrow M. A phosphorylation-regulated brake mechanism controls the initial endocytosis of opioid receptors but is not required for post-endocytic sorting to lysosomes. The Journal of Biological Chemistry. 276: 34331-8. PMID 11443128 DOI: 10.1074/Jbc.M104627200  0.863
2001 Carroll RC, Beattie EC, von Zastrow M, Malenka RC. Role of AMPA receptor endocytosis in synaptic plasticity. Nature Reviews. Neuroscience. 2: 315-24. PMID 11331915 DOI: 10.1038/35072500  0.551
2001 Tsao PI, von Zastrow M. Diversity and specificity in the regulated endocytic membrane trafficking of G-protein-coupled receptors. Pharmacology & Therapeutics. 89: 139-47. PMID 11316517 DOI: 10.1016/S0163-7258(00)00107-8  0.85
2001 Klein U, Müller C, Chu P, Birnbaumer M, von Zastrow M. Heterologous inhibition of G protein-coupled receptor endocytosis mediated by receptor-specific trafficking of beta-arrestins. The Journal of Biological Chemistry. 276: 17442-7. PMID 11278476 DOI: 10.1074/jbc.M009214200  0.498
2001 Tsao P, Cao T, von Zastrow M. Role of endocytosis in mediating downregulation of G-protein-coupled receptors. Trends in Pharmacological Sciences. 22: 91-6. PMID 11166853 DOI: 10.1016/S0165-6147(00)01620-5  0.881
2000 Whistler J, Beattie E, von Zastrow M. Tales from the crypt: evidence for heptahelical receptor signaling in the endocytic pathway. Science's Stke : Signal Transduction Knowledge Environment. 2000: pe1. PMID 11752604 DOI: 10.1126/Stke.2000.47.Pe1  0.561
2000 Beattie EC, Carroll RC, Yu X, Morishita W, Yasuda H, von Zastrow M, Malenka RC. Regulation of AMPA receptor endocytosis by a signaling mechanism shared with LTD. Nature Neuroscience. 3: 1291-300. PMID 11100150 DOI: 10.1038/81823  0.7
2000 Tsao P, von Zastrow M. Downregulation of G protein-coupled receptors. Current Opinion in Neurobiology. 10: 365-9. PMID 10851176 DOI: 10.1016/S0959-4388(00)00096-9  0.856
2000 Tsao PI, von Zastrow M. Type-specific sorting of G protein-coupled receptors after endocytosis. The Journal of Biological Chemistry. 275: 11130-40. PMID 10753919 DOI: 10.1074/Jbc.275.15.11130  0.881
1999 Lüscher C, Xia H, Beattie EC, Carroll RC, von Zastrow M, Malenka RC, Nicoll RA. Role of AMPA receptor cycling in synaptic transmission and plasticity. Neuron. 24: 649-58. PMID 10595516 DOI: 10.1016/S0896-6273(00)81119-8  0.637
1999 Carroll RC, Beattie EC, Xia H, Lüscher C, Altschuler Y, Nicoll RA, Malenka RC, von Zastrow M. Dynamin-dependent endocytosis of ionotropic glutamate receptors. Proceedings of the National Academy of Sciences of the United States of America. 96: 14112-7. PMID 10570207 DOI: 10.1073/pnas.96.24.14112  0.732
1999 Cao TT, Deacon HW, Reczek D, Bretscher A, von Zastrow M. A kinase-regulated PDZ-domain interaction controls endocytic sorting of the beta2-adrenergic receptor. Nature. 401: 286-90. PMID 10499588 DOI: 10.1038/45816  0.539
1999 Whistler JL, Chuang HH, Chu P, Jan LY, von Zastrow M. Functional dissociation of mu opioid receptor signaling and endocytosis: implications for the biology of opiate tolerance and addiction. Neuron. 23: 737-46. PMID 10482240 DOI: 10.1016/S0896-6273(01)80032-5  0.695
1999 Whistler JL, von Zastrow M. Dissociation of functional roles of dynamin in receptor-mediated endocytosis and mitogenic signal transduction. The Journal of Biological Chemistry. 274: 24575-8. PMID 10455121 DOI: 10.1074/Jbc.274.35.24575  0.561
1999 Lissin DV, Malenka RC, Von Zastrow M. An immunocytochemical assay for activity-dependent redistribution of glutamate receptors from the postsynaptic plasma membrane. Annals of the New York Academy of Sciences. 868: 550-3. PMID 10414334 DOI: 10.1111/j.1749-6632.1999.tb11326.x  0.62
1999 Carroll RC, Lissin DV, von Zastrow M, Nicoll RA, Malenka RC. Rapid redistribution of glutamate receptors contributes to long-term depression in hippocampal cultures. Nature Neuroscience. 2: 454-60. PMID 10321250 DOI: 10.1038/8123  0.582
1999 Lissin DV, Carroll RC, Nicoll RA, Malenka RC, von Zastrow M. Rapid, activation-induced redistribution of ionotropic glutamate receptors in cultured hippocampal neurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 19: 1263-72. PMID 9952404 DOI: 10.1523/Jneurosci.19-04-01263.1999  0.604
1999 Vickery RG, von Zastrow M. Distinct dynamin-dependent and -independent mechanisms target structurally homologous dopamine receptors to different endocytic membranes. The Journal of Cell Biology. 144: 31-43. PMID 9885242 DOI: 10.1083/jcb.144.1.31  0.562
1998 Cao TT, Mays RW, von Zastrow M. Regulated endocytosis of G-protein-coupled receptors by a biochemically and functionally distinct subpopulation of clathrin-coated pits. The Journal of Biological Chemistry. 273: 24592-602. PMID 9733754 DOI: 10.1074/jbc.273.38.24592  0.465
1998 Whistler JL, von Zastrow M. Morphine-activated opioid receptors elude desensitization by beta-arrestin. Proceedings of the National Academy of Sciences of the United States of America. 95: 9914-9. PMID 9707575 DOI: 10.1073/Pnas.95.17.9914  0.561
1998 Lissin DV, Gomperts SN, Carroll RC, Christine CW, Kalman D, Kitamura M, Hardy S, Nicoll RA, Malenka RC, von Zastrow M. Activity differentially regulates the surface expression of synaptic AMPA and NMDA glutamate receptors. Proceedings of the National Academy of Sciences of the United States of America. 95: 7097-102. PMID 9618545 DOI: 10.1073/Pnas.95.12.7097  0.635
1998 Keith DE, Anton B, Murray SR, Zaki PA, Chu PC, Lissin DV, Monteillet-Agius G, Stewart PL, Evans CJ, von Zastrow M. mu-Opioid receptor internalization: opiate drugs have differential effects on a conserved endocytic mechanism in vitro and in the mammalian brain. Molecular Pharmacology. 53: 377-84. PMID 9495801 DOI: 10.1124/Mol.53.3.377  0.446
1997 Klein U, Ramirez MT, Kobilka BK, von Zastrow M. A novel interaction between adrenergic receptors and the alpha-subunit of eukaryotic initiation factor 2B. The Journal of Biological Chemistry. 272: 19099-102. PMID 9235896 DOI: 10.1074/jbc.272.31.19099  0.77
1996 Mostafapour S, Kobilka BK, von Zastrow M. Pharmacological sequestration of a chimeric beta 3/beta 2 adrenergic receptor occurs without a corresponding amount of receptor internalization. Receptors & Signal Transduction. 6: 151-63. PMID 9259050  0.77
1996 Keith DE, Murray SR, Zaki PA, Chu PC, Lissin DV, Kang L, Evans CJ, von Zastrow M. Morphine activates opioid receptors without causing their rapid internalization. The Journal of Biological Chemistry. 271: 19021-4. PMID 8702570 DOI: 10.1074/Jbc.271.32.19021  0.491
1994 von Zastrow M, Kobilka BK. Antagonist-dependent and -independent steps in the mechanism of adrenergic receptor internalization. The Journal of Biological Chemistry. 269: 18448-52. PMID 7518433  0.773
1994 von Zastrow M, Keith D, Zaki P, Evans C. Intracellular trafficking of epitope-tagged opioid receptors: Different effects of morphine and enkephalin Regulatory Peptides. 54: 315-316. DOI: 10.1016/0167-0115(94)90516-9  0.353
1992 von Zastrow M, Kobilka BK. Ligand-regulated internalization and recycling of human beta 2-adrenergic receptors between the plasma membrane and endosomes containing transferrin receptors. The Journal of Biological Chemistry. 267: 3530-8. PMID 1371121  0.771
1992 Suryanarayana S, von Zastrow M, Kobilka BK. Identification of intramolecular interactions in adrenergic receptors. The Journal of Biological Chemistry. 267: 21991-4. PMID 1331041  0.761
1991 Suryanarayana S, Daunt DA, Von Zastrow M, Kobilka BK. A single point mutation in the seventh hydrophobic domain of the alpha 2-adrenergic receptor changes antagonist binding specificity to that of a beta receptor. Transactions of the Association of American Physicians. 104: 62-8. PMID 1688262  0.697
1991 Suryanarayana S, Daunt DA, Von Zastrow M, Kobilka BK. A point mutation in the seventh hydrophobic domain of the alpha 2 adrenergic receptor increases its affinity for a family of beta receptor antagonists. The Journal of Biological Chemistry. 266: 15488-92. PMID 1678390  0.688
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