R. Adron Harris - Publications

Affiliations: 
University of Texas at Austin, Austin, Texas, U.S.A. 
Area:
Neuropharmacology

316 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Kisby BR, Farris SP, McManus MM, Varodayan FP, Roberto M, Harris RA, Ponomarev I. Alcohol Dependence in Rats Is Associated with Global Changes in Gene Expression in the Central Amygdala. Brain Sciences. 11. PMID 34573170 DOI: 10.3390/brainsci11091149  0.821
2020 Blednov YA, Borghese CM, Dugan MP, Pradhan S, Thodati TM, Kichili NR, Harris RA, Messing RO. Apremilast regulates acute effects of ethanol and other GABAergic drugs via protein kinase A-dependent signaling. Neuropharmacology. 108220. PMID 32736086 DOI: 10.1016/J.Neuropharm.2020.108220  0.372
2020 Grantham EK, Warden AS, McCarthy GS, DaCosta A, Mason S, Blednov Y, Mayfield RD, Harris RA. Role of TLR7 in voluntary alcohol consumption. Brain, Behavior, and Immunity. PMID 32726684 DOI: 10.1016/J.Bbi.2020.07.029  0.761
2020 Warden AS, Wolfe SA, Khom S, Varodayan FP, Patel RR, Steinman MQ, Bajo M, Montgomery SE, Vlkolinsky R, Nadav T, Polis I, Roberts AJ, Mayfield RD, Harris RA, Roberto M. Microglia Control Escalation of Drinking in Alcohol-Dependent Mice: Genomic and Synaptic Drivers. Biological Psychiatry. PMID 32680583 DOI: 10.1016/J.Biopsych.2020.05.011  0.354
2020 Warden AS, DaCosta A, Mason S, Blednov YA, Mayfield RD, Harris RA. Inbred Substrain Differences Influence Neuroimmune Response and Drinking Behavior. Alcoholism, Clinical and Experimental Research. PMID 32640038 DOI: 10.1111/Acer.14410  0.728
2020 Blednov YA, Da Costa A, Mayfield J, Harris RA, Messing RO. Deletion of Tlr3 reduces acute tolerance to alcohol and alcohol consumption in the intermittent access procedure in male mice. Addiction Biology. e12932. PMID 32604471 DOI: 10.1111/Adb.12932  0.483
2020 Erickson EK, DaCosta AJ, Mason SC, Blednov YA, Mayfield RD, Harris RA. Cortical astrocytes regulate ethanol consumption and intoxication in mice. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 32464636 DOI: 10.1038/S41386-020-0721-0  0.749
2020 Warden AS, Triplett TA, Lyu A, Grantham EK, Azzam MM, DaCosta A, Mason S, Blednov YA, Ehrlich LIR, Mayfield RD, Harris RA. Microglia depletion and alcohol: Transcriptome and behavioral profiles. Addiction Biology. e12889. PMID 32176824 DOI: 10.1111/Adb.12889  0.793
2019 Ferguson LB, Patil S, Moskowitz BA, Ponomarev I, Harris RA, Mayfield RD, Messing RO. A Pathway-Based Genomic Approach to Identify Medications: Application to Alcohol Use Disorder. Brain Sciences. 9. PMID 31888299 DOI: 10.3390/Brainsci9120381  0.8
2019 Erickson EK, Blednov YA, Harris RA, Mayfield RD. Glial gene networks associated with alcohol dependence. Scientific Reports. 9: 10949. PMID 31358844 DOI: 10.1038/S41598-019-47454-4  0.796
2019 Chung T, Harris RA. Cannabis and Alcohol: From Basic Science to Public Policy. Alcoholism, Clinical and Experimental Research. PMID 31265135 DOI: 10.1111/Acer.14144  0.414
2018 Erickson EK, Grantham EK, Warden AS, Harris RA. Neuroimmune signaling in alcohol use disorder. Pharmacology, Biochemistry, and Behavior. 177: 34-60. PMID 30590091 DOI: 10.1016/j.pbb.2018.12.007  0.327
2018 Warden AS, Azzam M, DaCosta A, Mason S, Blednov YA, Messing RO, Mayfield RD, Harris RA. Toll-like receptor 3 activation increases voluntary alcohol intake in C57BL/6J male mice. Brain, Behavior, and Immunity. PMID 30550931 DOI: 10.1016/J.Bbi.2018.12.004  0.797
2018 Warden AS, Azzam MM, DaCosta A, Mason S, Blednov YA, Messing RO, Mayfield RD, Harris RA. Toll-like receptor 3 dynamics in female C57BL/6J mice: Regulation of alcohol intake. Brain, Behavior, and Immunity. PMID 30550930 DOI: 10.1016/J.Bbi.2018.12.006  0.452
2018 Mayfield RD, Harris RA. Persistence of Drug Memories: Melting Transcriptomes. Biological Psychiatry. 84: 860-861. PMID 30466505 DOI: 10.1016/J.Biopsych.2018.09.023  0.683
2018 Wolfe SA, Farris SP, Mayfield JE, Heaney CF, Erickson EK, Harris RA, Mayfield RD, Raab-Graham KF. Ethanol and a rapid-acting antidepressant produce overlapping changes in exon expression in the synaptic transcriptome. Neuropharmacology. PMID 30419244 DOI: 10.1016/J.Neuropharm.2018.11.007  0.757
2018 Ferguson LB, Zhang L, Wang S, Bridges C, Harris RA, Ponomarev I. Peroxisome Proliferator Activated Receptor Agonists Modulate Transposable Element Expression in Brain and Liver. Frontiers in Molecular Neuroscience. 11: 331. PMID 30283300 DOI: 10.3389/Fnmol.2018.00331  0.595
2018 Ferguson LB, Zhang L, Kircher D, Wang S, Mayfield RD, Crabbe JC, Morrisett RA, Harris RA, Ponomarev I. Dissecting Brain Networks Underlying Alcohol Binge Drinking Using a Systems Genomics Approach. Molecular Neurobiology. PMID 30062672 DOI: 10.1007/S12035-018-1252-0  0.839
2018 Most D, Salem NA, Tiwari GR, Blednov YA, Mayfield RD, Harris RA. Silencing synaptic MicroRNA-411 reduces voluntary alcohol consumption in mice. Addiction Biology. PMID 29665166 DOI: 10.1111/Adb.12625  0.788
2018 Ferguson LB, Harris RA, Mayfield RD. From gene networks to drugs: systems pharmacology approaches for AUD. Psychopharmacology. PMID 29497781 DOI: 10.1007/S00213-018-4855-2  0.751
2018 Blednov YA, Da Costa AJ, Tarbox T, Ponomareva O, Messing RO, Harris RA. Apremilast Alters Behavioral Responses to Ethanol in Mice: I. Reduced Ethanol Consumption and Preference. Alcoholism, Clinical and Experimental Research. PMID 29469962 DOI: 10.1111/Acer.13616  0.367
2018 Blednov YA, Da Costa AJ, Harris RA, Messing RO. Apremilast Alters Behavioral Responses to Ethanol in Mice: II. Increased Sedation, Intoxication and Reduced Acute Functional Tolerance. Alcoholism, Clinical and Experimental Research. PMID 29469954 DOI: 10.1111/Acer.13615  0.375
2018 Osterndorff-Kahanek EA, Tiwari GR, Lopez MF, Becker HC, Harris RA, Mayfield RD. Long-term ethanol exposure: Temporal pattern of microRNA expression and associated mRNA gene networks in mouse brain. Plos One. 13: e0190841. PMID 29315347 DOI: 10.1371/Journal.Pone.0190841  0.752
2018 Erickson EK, Farris SP, Blednov YA, Mayfield RD, Harris RA. Astrocyte-specific transcriptome responses to chronic ethanol consumption. The Pharmacogenomics Journal. PMID 29305589 DOI: 10.1038/S41397-017-0012-2  0.81
2017 Ferguson LB, Ozburn AR, Ponomarev I, Metten P, Reilly M, Crabbe JC, Harris RA, Mayfield RD. Genome-Wide Expression Profiles Drive Discovery of Novel Compounds that Reduce Binge Drinking in Mice. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 29251283 DOI: 10.1038/Npp.2017.301  0.822
2017 McCarthy GM, Farris SP, Blednov YA, Harris RA, Mayfield RD. Microglial-specific transcriptome changes following chronic alcohol consumption. Neuropharmacology. PMID 29101021 DOI: 10.1016/J.Neuropharm.2017.10.035  0.841
2017 Tarvin RD, Borghese CM, Sachs W, Santos JC, Lu Y, O'Connell LA, Cannatella DC, Harris RA, Zakon HH. Interacting amino acid replacements allow poison frogs to evolve epibatidine resistance. Science (New York, N.Y.). 357: 1261-1266. PMID 28935799 DOI: 10.1126/Science.Aan5061  0.304
2017 McCracken LM, Lowes DC, Salling MC, Carreau-Vollmer C, Odean NN, Blednov YA, Betz H, Harris RA, Harrison NL. Glycine receptor α3 and α2 subunits mediate tonic and exogenous agonist-induced currents in forebrain. Proceedings of the National Academy of Sciences of the United States of America. PMID 28784756 DOI: 10.1073/Pnas.1703839114  0.571
2017 Borghese CM, Herman M, Snell LD, Lawrence KJ, Lee HY, Backos DS, Vanderlinden LA, Harris RA, Roberto M, Hoffman PL, Tabakoff B. Novel Molecule Exhibiting Selective Affinity for GABAA Receptor Subtypes. Scientific Reports. 7: 6230. PMID 28740086 DOI: 10.1038/S41598-017-05966-X  0.425
2017 Harris RA, Koob GF. The future is now: A 2020 view of alcoholism research. Neuropharmacology. 122: 1-2. PMID 28633760 DOI: 10.1016/J.Neuropharm.2017.06.001  0.412
2017 Blednov YA, Borghese CM, Ruiz CI, Cullins MA, Da Costa A, Osterndorff-Kahanek EA, Homanics GE, Harris RA. Mutation of the inhibitory ethanol site in GABAA ρ1 receptors promotes tolerance to ethanol-induced motor incoordination. Neuropharmacology. PMID 28623169 DOI: 10.1016/J.Neuropharm.2017.06.013  0.455
2017 Ponomarev I, Stelly CE, Morikawa H, Blednov YA, Mayfield RD, Harris RA. Mechanistic insights into epigenetic modulation of ethanol consumption. Alcohol (Fayetteville, N.Y.). PMID 28433417 DOI: 10.1016/J.Alcohol.2017.01.016  0.809
2017 Blednov YA, Black M, Benavidez JM, Da Costa A, Mayfield J, Harris RA. Sedative and Motor Incoordination Effects of Ethanol in Mice Lacking CD14, TLR2, TLR4, or MyD88. Alcoholism, Clinical and Experimental Research. PMID 28160299 DOI: 10.1111/Acer.13314  0.387
2017 Blednov YA, Black M, Chernis J, Da Costa A, Mayfield J, Harris RA. Ethanol Consumption in Mice Lacking CD14, TLR2, TLR4, or MyD88. Alcoholism, Clinical and Experimental Research. PMID 28146272 DOI: 10.1111/Acer.13316  0.465
2017 Mayfield J, Harris RA. The Neuroimmune Basis of Excessive Alcohol Consumption. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 42: 376. PMID 27909320 DOI: 10.1038/npp.2016.177  0.344
2017 Warden AS, DaCosta A, Blednov YA, Mayfield RD, Harris RA. TLR3 activation increases voluntary alcohol consumption Alcohol. 60: 242. DOI: 10.1016/J.Alcohol.2017.02.348  0.777
2017 Harris RA, Warden AS, Mayfield RD, Blednov YA. Neuroimmune regulation of alcohol consumption Alcohol. 60: 220-221. DOI: 10.1016/J.Alcohol.2017.02.259  0.786
2017 Farris SP, Iancu O, Hitzemann R, Grant K, Walter NAR, Harris RA, Mayfield RD. Integrative analysis of human and non-human primate brain tissue for alcohol consumption Alcohol. 60: 213. DOI: 10.1016/J.Alcohol.2017.02.227  0.804
2016 Harris RA, Bajo M, Bell RL, Blednov YA, Varodayan FP, Truitt J, de Guglielmo G, Lasek AW, Logrip ML, Vendruscolo LF, Roberts AJ, Roberts E, George O, Mayfield J, Billiar TR, et al. Genetic and pharmacologic manipulation of TLR4 has minimal impact on ethanol consumption in rodents. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 27986929 DOI: 10.1523/Jneurosci.2002-16.2016  0.776
2016 Warden A, Erickson E, Robinson G, Harris RA, Mayfield RD. The neuroimmune transcriptome and alcohol dependence: potential for targeted therapies. Pharmacogenomics. PMID 27918243 DOI: 10.2217/Pgs-2016-0062  0.796
2016 Tulisiak CT, Harris RA, Ponomarev I. DNA modifications in models of alcohol use disorders. Alcohol (Fayetteville, N.Y.). PMID 27865607 DOI: 10.1016/J.Alcohol.2016.11.004  0.624
2016 Truitt JM, Blednov YA, Benavidez JM, Black M, Ponomareva O, Law J, Merriman M, Horani S, Jameson K, Lasek AW, Harris RA, Mayfield RD. Inhibition of IKKβ Reduces Ethanol Consumption in C57BL/6J Mice. Eneuro. 3. PMID 27822501 DOI: 10.1523/ENEURO.0256-16.2016  0.771
2016 Wolfe SA, Workman ER, Heaney CF, Niere F, Namjoshi S, Cacheaux LP, Farris SP, Drew MR, Zemelman BV, Harris RA, Raab-Graham KF. FMRP regulates an ethanol-dependent shift in GABABR function and expression with rapid antidepressant properties. Nature Communications. 7: 12867. PMID 27666021 DOI: 10.1038/Ncomms12867  0.773
2016 McCracken ML, Gorini G, McCracken LM, Mayfield RD, Harris RA, Trudell JR. Inter- and Intra-Subunit Butanol/Isoflurane Sites of Action in the Human Glycine Receptor. Frontiers in Molecular Neuroscience. 9: 45. PMID 27378846 DOI: 10.3389/Fnmol.2016.00045  0.808
2016 Warden A, Truitt J, Merriman M, Ponomareva O, Jameson K, Ferguson LB, Mayfield RD, Harris RA. Localization of PPAR isotypes in the adult mouse and human brain. Scientific Reports. 6: 27618. PMID 27283430 DOI: 10.1038/Srep27618  0.733
2016 Mayfield J, Arends MA, Harris RA, Blednov YA. Genes and Alcohol Consumption: Studies with Mutant Mice. International Review of Neurobiology. 126: 293-355. PMID 27055617 DOI: 10.1016/Bs.Irn.2016.02.014  0.396
2016 Blednov YA, Black M, Benavidez JM, Stamatakis EE, Harris RA. PPAR Agonists: I. Role of Receptor Subunits in Alcohol Consumption in Male and Female Mice. Alcoholism, Clinical and Experimental Research. PMID 26857685 DOI: 10.1111/Acer.12976  0.355
2016 Blednov YA, Black M, Benavidez JM, Stamatakis EE, Harris RA. PPAR Agonists: II. Fenofibrate and Tesaglitazar Alter Behaviors Related to Voluntary Alcohol Consumption. Alcoholism, Clinical and Experimental Research. PMID 26857541 DOI: 10.1111/Acer.12972  0.468
2016 Trudell JR, Borghese CM, Ruiz CI, Lee US, Cullins MA, Bertaccini EJ, Harris RA. Identification of an Inhibitory Alcohol Binding Site in GABAaRho1 Biophysical Journal. 110. DOI: 10.1016/J.Bpj.2015.11.2311  0.499
2015 Borghese CM, Ruiz CI, Lee US, Cullins MA, Bertaccini EJ, Trudell JR, Harris RA. Identification of an Inhibitory Alcohol Binding Site in GABAA ρ1 Receptors. Acs Chemical Neuroscience. PMID 26571107 DOI: 10.1021/Acschemneuro.5B00246  0.478
2015 Marballi K, Genabai NK, Blednov YA, Harris RA, Ponomarev I. Alcohol consumption induces global gene expression changes in VTA dopaminergic neurons. Genes, Brain, and Behavior. PMID 26482798 DOI: 10.1111/Gbb.12266  0.635
2015 Mayfield J, Blednov YA, Harris RA. Behavioral and Genetic Evidence for GIRK Channels in the CNS: Role in Physiology, Pathophysiology, and Drug Addiction. International Review of Neurobiology. 123: 279-313. PMID 26422988 DOI: 10.1016/Bs.Irn.2015.05.016  0.304
2015 Kim YD, Lee KM, Hwang SL, Chang HW, Kim KJ, Harris RA, Choi HS, Choi WS, Lee SE, Park CS. Inhibition of cereblon by fenofibrate ameliorates alcoholic liver disease by enhancing AMPK. Biochimica Et Biophysica Acta. PMID 26410577 DOI: 10.1016/J.Bbadis.2015.09.014  0.347
2015 Most D, Leiter C, Blednov YA, Harris RA, Mayfield RD. Synaptic microRNAs Coordinately Regulate Synaptic mRNAs: Perturbation by Chronic Alcohol Consumption. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 26105134 DOI: 10.1038/Npp.2015.179  0.785
2015 Cui C, Noronha A, Warren KR, Koob GF, Sinha R, Thakkar M, Matochik J, Crews FT, Chandler LJ, Pfefferbaum A, Becker HC, Lovinger D, Everitt BJ, Egli M, Mandyam CD, ... Harris RA, et al. Brain pathways to recovery from alcohol dependence. Alcohol (Fayetteville, N.Y.). 49: 435-52. PMID 26074423 DOI: 10.1016/J.Alcohol.2015.04.006  0.439
2015 Farris SP, Harris RA, Ponomarev I. Epigenetic modulation of brain gene networks for cocaine and alcohol abuse. Frontiers in Neuroscience. 9: 176. PMID 26041984 DOI: 10.3389/Fnins.2015.00176  0.787
2015 Horani S, Stater EP, Corringer PJ, Trudell JR, Harris RA, Howard RJ. Ethanol Modulation is Quantitatively Determined by the Transmembrane Domain of Human α1 Glycine Receptors. Alcoholism, Clinical and Experimental Research. 39: 962-8. PMID 25973519 DOI: 10.1111/Acer.12735  0.37
2015 Farris SP, Pietrzykowski AZ, Miles MF, O'Brien MA, Sanna PP, Zakhari S, Mayfield RD, Harris RA. Applying the new genomics to alcohol dependence. Alcohol (Fayetteville, N.Y.). PMID 25896098 DOI: 10.1016/J.Alcohol.2015.03.001  0.826
2015 Blednov YA, Benavidez JM, Black M, Mayfield J, Harris RA. Role of interleukin-1 receptor signaling in the behavioral effects of ethanol and benzodiazepines. Neuropharmacology. 95: 309-20. PMID 25839897 DOI: 10.1016/J.Neuropharm.2015.03.015  0.387
2015 Osterndorff-Kahanek EA, Becker HC, Lopez MF, Farris SP, Tiwari GR, Nunez YO, Harris RA, Mayfield RD. Chronic ethanol exposure produces time- and brain region-dependent changes in gene coexpression networks. Plos One. 10: e0121522. PMID 25803291 DOI: 10.1371/Journal.Pone.0121522  0.797
2015 Blednov YA, Benavidez JM, Black M, Leiter CR, Osterndorff-Kahanek E, Harris RA. Glycine receptors containing α2 or α3 subunits regulate specific ethanol-mediated behaviors. The Journal of Pharmacology and Experimental Therapeutics. 353: 181-91. PMID 25678534 DOI: 10.1124/Jpet.114.221895  0.436
2015 Blednov YA, Benavidez JM, Black M, Ferguson LB, Schoenhard GL, Goate AM, Edenberg HJ, Wetherill L, Hesselbrock V, Foroud T, Harris RA. Peroxisome proliferator-activated receptors α and γ are linked with alcohol consumption in mice and withdrawal and dependence in humans. Alcoholism, Clinical and Experimental Research. 39: 136-45. PMID 25516156 DOI: 10.1111/Acer.12610  0.512
2015 Most D, Ferguson L, Blednov Y, Mayfield RD, Harris RA. The synaptoneurosome transcriptome: a model for profiling the emolecular effects of alcohol. The Pharmacogenomics Journal. 15: 177-88. PMID 25135349 DOI: 10.1038/Tpj.2014.43  0.788
2014 Most D, Workman E, Harris RA. Synaptic adaptations by alcohol and drugs of abuse: changes in microRNA expression and mRNA regulation. Frontiers in Molecular Neuroscience. 7: 85. PMID 25565954 DOI: 10.3389/Fnmol.2014.00085  0.345
2014 Farris SP, Arasappan D, Hunicke-Smith S, Harris RA, Mayfield RD. Transcriptome organization for chronic alcohol abuse in human brain. Molecular Psychiatry. PMID 25450227 DOI: 10.1038/Mp.2014.159  0.839
2014 Most D, Ferguson L, Harris RA. Molecular basis of alcoholism. Handbook of Clinical Neurology. 125: 89-111. PMID 25307570 DOI: 10.1016/B978-0-444-62619-6.00006-9  0.486
2014 Robinson G, Most D, Ferguson LB, Mayfield J, Harris RA, Blednov YA. Neuroimmune pathways in alcohol consumption: evidence from behavioral and genetic studies in rodents and humans. International Review of Neurobiology. 118: 13-39. PMID 25175860 DOI: 10.1016/B978-0-12-801284-0.00002-6  0.488
2014 Ferguson LB, Most D, Blednov YA, Harris RA. PPAR agonists regulate brain gene expression: relationship to their effects on ethanol consumption. Neuropharmacology. 86: 397-407. PMID 25036611 DOI: 10.1016/J.Neuropharm.2014.06.024  0.478
2014 Blednov YA, Benavidez JM, Black M, Harris RA. Inhibition of phosphodiesterase 4 reduces ethanol intake and preference in C57BL/6J mice. Frontiers in Neuroscience. 8: 129. PMID 24904269 DOI: 10.3389/Fnins.2014.00129  0.447
2014 Trudell JR, Messing RO, Mayfield J, Harris RA. Alcohol dependence: molecular and behavioral evidence. Trends in Pharmacological Sciences. 35: 317-23. PMID 24865944 DOI: 10.1016/J.Tips.2014.04.009  0.493
2014 Bajo M, Madamba SG, Roberto M, Blednov YA, Sagi VN, Roberts E, Rice KC, Harris RA, Siggins GR. Innate immune factors modulate ethanol interaction with GABAergic transmission in mouse central amygdala. Brain, Behavior, and Immunity. 40: 191-202. PMID 24675033 DOI: 10.1016/J.Bbi.2014.03.007  0.366
2014 Howard RJ, Trudell JR, Harris RA. Seeking structural specificity: direct modulation of pentameric ligand-gated ion channels by alcohols and general anesthetics. Pharmacological Reviews. 66: 396-412. PMID 24515646 DOI: 10.1124/Pr.113.007468  0.361
2014 Blednov YA, Benavidez JM, Black M, Leiter CR, Osterndorff-Kahanek E, Johnson D, Borghese CM, Hanrahan JR, Johnston GA, Chebib M, Harris RA. GABAA receptors containing ρ1 subunits contribute to in vivo effects of ethanol in mice. Plos One. 9: e85525. PMID 24454882 DOI: 10.1371/Journal.Pone.0085525  0.428
2014 Lee C, Mayfield RD, Harris RA. Altered gamma-aminobutyric acid type B receptor subunit 1 splicing in alcoholics. Biological Psychiatry. 75: 765-73. PMID 24209778 DOI: 10.1016/J.Biopsych.2013.08.028  0.809
2014 Borghese CM, Hicks JA, Lapid DJ, Trudell JR, Harris RA. GABA(A) receptor transmembrane amino acids are critical for alcohol action: disulfide cross-linking and alkyl methanethiosulfonate labeling reveal relative location of binding sites. Journal of Neurochemistry. 128: 363-75. PMID 24117469 DOI: 10.1111/Jnc.12476  0.431
2014 Gorini G, Harris RA, Mayfield RD. Proteomic approaches and identification of novel therapeutic targets for alcoholism. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 39: 104-30. PMID 23900301 DOI: 10.1038/Npp.2013.182  0.809
2014 Marballi K, Ponomarev I, Mayfield RD, Harris RA. Alcohol and the Brain: An Epigenetic Viewpoint Neurobiology of Alcohol Dependence. 349-358. DOI: 10.1016/B978-0-12-405941-2.00017-1  0.803
2014 Noronha A, Cui C, Harris RA, Crabbe JC. Neurobiology of Alcohol Dependence Neurobiology of Alcohol Dependence. 1-560.  0.566
2013 Ferguson C, McKay M, Harris RA, Homanics GE. Toll-like receptor 4 (Tlr4) knockout rats produced by transcriptional activator-like effector nuclease (TALEN)-mediated gene inactivation. Alcohol (Fayetteville, N.Y.). 47: 595-9. PMID 24199847 DOI: 10.1016/J.Alcohol.2013.09.043  0.348
2013 Nunez YO, Truitt JM, Gorini G, Ponomareva ON, Blednov YA, Harris RA, Mayfield RD. Positively correlated miRNA-mRNA regulatory networks in mouse frontal cortex during early stages of alcohol dependence. Bmc Genomics. 14: 725. PMID 24148570 DOI: 10.1186/1471-2164-14-725  0.795
2013 Heusser SA, Howard RJ, Borghese CM, Cullins MA, Broemstrup T, Lee US, Lindahl E, Carlsson J, Harris RA. Functional validation of virtual screening for novel agents with general anesthetic action at ligand-gated ion channels. Molecular Pharmacology. 84: 670-8. PMID 23950219 DOI: 10.1124/Mol.113.087692  0.332
2013 McCracken LM, Trudell JR, McCracken ML, Harris RA. Zinc-dependent modulation of α2- and α3-glycine receptor subunits by ethanol. Alcoholism, Clinical and Experimental Research. 37: 2002-10. PMID 23895467 DOI: 10.1111/Acer.12192  0.671
2013 Lee C, Harris RA, Wall JK, Mayfield RD, Wilke CO. RNaseIII and T4 polynucleotide Kinase sequence biases and solutions during RNA-seq library construction. Biology Direct. 8: 16. PMID 23826734 DOI: 10.1186/1745-6150-8-16  0.699
2013 Sauguet L, Howard RJ, Malherbe L, Lee US, Corringer PJ, Harris RA, Delarue M. Structural basis for potentiation by alcohols and anaesthetics in a ligand-gated ion channel. Nature Communications. 4: 1697. PMID 23591864 DOI: 10.1038/Ncomms2682  0.442
2013 Osterndorff-Kahanek E, Ponomarev I, Blednov YA, Harris RA. Gene expression in brain and liver produced by three different regimens of alcohol consumption in mice: comparison with immune activation. Plos One. 8: e59870. PMID 23555817 DOI: 10.1371/Journal.Pone.0059870  0.667
2013 Eberhart JK, Harris RA. Understanding variability in ethanol teratogenicity. Proceedings of the National Academy of Sciences of the United States of America. 110: 5285-6. PMID 23513226 DOI: 10.1073/Pnas.1302650110  0.329
2013 Mayfield J, Ferguson L, Harris RA. Neuroimmune signaling: a key component of alcohol abuse. Current Opinion in Neurobiology. 23: 513-20. PMID 23434064 DOI: 10.1016/J.Conb.2013.01.024  0.496
2013 Ozburn AR, Harris RA, Blednov YA. Chronic voluntary alcohol consumption results in tolerance to sedative/hypnotic and hypothermic effects of alcohol in hybrid mice. Pharmacology, Biochemistry, and Behavior. 104: 33-9. PMID 23313769 DOI: 10.1016/J.Pbb.2012.12.025  0.759
2013 McCracken LM, Blednov YA, Trudell JR, Benavidez JM, Betz H, Harris RA. Mutation of a zinc-binding residue in the glycine receptor α1 subunit changes ethanol sensitivity in vitro and alcohol consumption in vivo. The Journal of Pharmacology and Experimental Therapeutics. 344: 489-500. PMID 23230213 DOI: 10.1124/Jpet.112.197707  0.646
2013 Blednov YA, Benavidez JM, Black M, Chandra D, Homanics GE, Rudolph U, Harris RA. Linking GABA(A) receptor subunits to alcohol-induced conditioned taste aversion and recovery from acute alcohol intoxication. Neuropharmacology. 67: 46-56. PMID 23147414 DOI: 10.1016/J.Neuropharm.2012.10.016  0.33
2013 Howard RJ, Sauguet L, Broemstrup T, Murail S, Lee US, Horani S, Trudell JR, Corringer P, Lindahl E, Delarue M, Harris RA. Alcohol and Anesthetic Binding to Pentameric Ligand-Gated Ion Channels Revealed in a Prokaryotic Model System Biophysical Journal. 104: 635a-636a. DOI: 10.1016/J.Bpj.2012.11.3512  0.372
2013 Sauguet L, Howard R, Malherbe L, Lee US, Corringer P, Harris RA, Delarue M. X-Ray Structures of an Interfacial Potentiating Site for Alcohols and Anesthetics in a Pentameric Ligand-Gated Ion Channel Biophysical Journal. 104: 208a. DOI: 10.1016/J.Bpj.2012.11.1175  0.449
2013 Harris RA, Blednov YA. Neuroimmune genes and alcohol drinking behavior Neural-Immune Interactions in Brain Function and Alcohol Related Disorders. 425-440. DOI: 10.1007/978-1-4614-4729-0_13  0.335
2012 Borghese CM, Harris RA. Alcohol Dependence and Genes Encoding α2 and γ1 GABAA Receptor Subunits: Insights from Humans and Mice. Alcohol Research : Current Reviews. 34: 345-53. PMID 23134051  0.386
2012 Ozburn AR, Mayfield RD, Ponomarev I, Jones TA, Blednov YA, Harris RA. Chronic self-administration of alcohol results in elevated ΔFosB: comparison of hybrid mice with distinct drinking patterns. Bmc Neuroscience. 13: 130. PMID 23102405 DOI: 10.1186/1471-2202-13-130  0.835
2012 Murail S, Howard RJ, Broemstrup T, Bertaccini EJ, Harris RA, Trudell JR, Lindahl E. Molecular mechanism for the dual alcohol modulation of Cys-loop receptors. Plos Computational Biology. 8: e1002710. PMID 23055913 DOI: 10.1371/Journal.Pcbi.1002710  0.437
2012 Borghese CM, Xiong W, Oh SI, Ho A, Mihic SJ, Zhang L, Lovinger DM, Homanics GE, Eger EI, Harris RA. Mutations M287L and Q266I in the glycine receptor α1 subunit change sensitivity to volatile anesthetics in oocytes and neurons, but not the minimal alveolar concentration in knockin mice. Anesthesiology. 117: 765-71. PMID 22885675 DOI: 10.1097/Aln.0B013E31826A0D93  0.666
2012 Blednov YA, Mayfield RD, Belknap J, Harris RA. Behavioral actions of alcohol: phenotypic relations from multivariate analysis of mutant mouse data. Genes, Brain, and Behavior. 11: 424-35. PMID 22405477 DOI: 10.1111/J.1601-183X.2012.00780.X  0.776
2012 Ponomarev I, Wang S, Zhang L, Harris RA, Mayfield RD. Gene coexpression networks in human brain identify epigenetic modifications in alcohol dependence. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 1884-97. PMID 22302827 DOI: 10.1523/Jneurosci.3136-11.2012  0.833
2012 Johnson WD, Howard RJ, Trudell JR, Harris RA. The TM2 6' position of GABA(A) receptors mediates alcohol inhibition. The Journal of Pharmacology and Experimental Therapeutics. 340: 445-56. PMID 22072732 DOI: 10.1124/Jpet.111.188037  0.457
2012 Blednov YA, Benavidez JM, Homanics GE, Harris RA. Behavioral characterization of knockin mice with mutations M287L and Q266I in the glycine receptor α1 subunit. The Journal of Pharmacology and Experimental Therapeutics. 340: 317-29. PMID 22037202 DOI: 10.1124/Jpet.111.185124  0.382
2012 Borghese CM, Blednov YA, Quan Y, Iyer SV, Xiong W, Mihic SJ, Zhang L, Lovinger DM, Trudell JR, Homanics GE, Harris RA. Characterization of two mutations, M287L and Q266I, in the α1 glycine receptor subunit that modify sensitivity to alcohols. The Journal of Pharmacology and Experimental Therapeutics. 340: 304-16. PMID 22037201 DOI: 10.1124/Jpet.111.185116  0.725
2012 Blednov YA, Ponomarev I, Geil C, Bergeson S, Koob GF, Harris RA. Neuroimmune regulation of alcohol consumption: behavioral validation of genes obtained from genomic studies. Addiction Biology. 17: 108-20. PMID 21309947 DOI: 10.1111/J.1369-1600.2010.00284.X  0.678
2011 Etheridge N, Mayfield RD, Harris RA, Dodd PR. Identifying changes in the synaptic proteome of cirrhotic alcoholic superior frontal gyrus. Current Neuropharmacology. 9: 122-8. PMID 21886576 DOI: 10.2174/157015911795017164  0.779
2011 Howard RJ, Murail S, Ondricek KE, Corringer PJ, Lindahl E, Trudell JR, Harris RA. Structural basis for alcohol modulation of a pentameric ligand-gated ion channel. Proceedings of the National Academy of Sciences of the United States of America. 108: 12149-54. PMID 21730162 DOI: 10.1073/Pnas.1104480108  0.499
2011 Howard RJ, Slesinger PA, Davies DL, Das J, Trudell JR, Harris RA. Alcohol-binding sites in distinct brain proteins: the quest for atomic level resolution. Alcoholism, Clinical and Experimental Research. 35: 1561-73. PMID 21676006 DOI: 10.1111/J.1530-0277.2011.01502.X  0.451
2011 Lewohl JM, Nunez YO, Dodd PR, Tiwari GR, Harris RA, Mayfield RD. Up-regulation of microRNAs in brain of human alcoholics. Alcoholism, Clinical and Experimental Research. 35: 1928-37. PMID 21651580 DOI: 10.1111/J.1530-0277.2011.01544.X  0.78
2011 Johnson BA, Messing RO, Charness ME, Crabbe JC, Goldman MS, Harris RA, Kranzler HR, Jr MC, Nixon SJ, Riley EP, Schuckit MA, Sher KJ, Thomas JD. How Should Addiction-Related Research at the National Institutes of Health be Reorganized? Frontiers in Psychiatry. 2: 2. PMID 21629835 DOI: 10.3389/Fpsyt.2011.00002  0.532
2011 Johnson BA, Messing RO, Charness ME, Crabbe JC, Goldman MS, Harris RA, Kranzler HR, Mitchell MC, Nixon SJ, Riley EP, Schuckit MA, Sher KJ, Thomas JD. Should the reorganization of addiction-related research across all the National Institutes of Health be structural?--The devil is truly in the details. Alcoholism, Clinical and Experimental Research. 35: 572-80. PMID 21443646 DOI: 10.1111/J.1530-0277.2011.01493.X  0.568
2011 Morikawa H, Harris RA. Small K channels: big targets for treating alcoholism? Biological Psychiatry. 69: 614-5. PMID 21397742 DOI: 10.1016/J.Biopsych.2011.01.016  0.495
2011 Crabbe JC, Harris RA, Koob GF. Preclinical studies of alcohol binge drinking. Annals of the New York Academy of Sciences. 1216: 24-40. PMID 21272009 DOI: 10.1111/J.1749-6632.2010.05895.X  0.617
2011 Blednov YA, Benavidez JM, Geil C, Perra S, Morikawa H, Harris RA. Activation of inflammatory signaling by lipopolysaccharide produces a prolonged increase of voluntary alcohol intake in mice. Brain, Behavior, and Immunity. 25: S92-S105. PMID 21266194 DOI: 10.1016/J.Bbi.2011.01.008  0.352
2011 Mulligan MK, Rhodes JS, Crabbe JC, Mayfield RD, Harris RA, Ponomarev I. Molecular profiles of drinking alcohol to intoxication in C57BL/6J mice. Alcoholism, Clinical and Experimental Research. 35: 659-70. PMID 21223303 DOI: 10.1111/J.1530-0277.2010.01384.X  0.841
2011 Harris RA, Osterndorff-Kahanek E, Ponomarev I, Homanics GE, Blednov YA. Testing the silence of mutations: Transcriptomic and behavioral studies of GABA(A) receptor α1 and α2 subunit knock-in mice. Neuroscience Letters. 488: 31-5. PMID 21056629 DOI: 10.1016/J.Neulet.2010.10.075  0.569
2011 Blednov YA, Borghese CM, McCracken ML, Benavidez JM, Geil CR, Osterndorff-Kahanek E, Werner DF, Iyer S, Swihart A, Harrison NL, Homanics GE, Harris RA. Loss of ethanol conditioned taste aversion and motor stimulation in knockin mice with ethanol-insensitive α2-containing GABA(A) receptors. The Journal of Pharmacology and Experimental Therapeutics. 336: 145-54. PMID 20876231 DOI: 10.1124/Jpet.110.171645  0.347
2011 Howard RJ, Ondricek KE, Trudell JR, Harris RA. Structural Basis for Alcohol Modulation of a Ligand-Gated Ion Channel Homolog Biophysical Journal. 100: 101a. DOI: 10.1016/J.Bpj.2010.12.756  0.494
2011 Borghese CM, harris RA. Alcohol dependence and genes encoding α2 and γ1 GABAA receptor subunits insights from humans and mice Alcohol Research and Health. 34: 345-354.  0.339
2010 McCracken LM, McCracken ML, Gong DH, Trudell JR, Harris RA. Linking of Glycine Receptor Transmembrane Segments Three and Four Allows Assignment of Intrasubunit-Facing Residues. Acs Chemical Neuroscience. 1: 482. PMID 21326622 DOI: 10.1021/cn100019g  0.558
2010 Lee C, Mayfield RD, Harris RA. Intron 4 containing novel GABAB1 isoforms impair GABAB receptor function. Plos One. 5: e14044. PMID 21124972 DOI: 10.1371/Journal.Pone.0014044  0.751
2010 McCracken ML, Borghese CM, Trudell JR, Harris RA. A transmembrane amino acid in the GABAA receptor β2 subunit critical for the actions of alcohols and anesthetics. The Journal of Pharmacology and Experimental Therapeutics. 335: 600-6. PMID 20826568 DOI: 10.1124/Jpet.110.170472  0.471
2010 Ozburn AR, Harris RA, Blednov YA. Behavioral differences between C57BL/6J x FVB/NJ and C57BL/6J x NZB/B1NJ F1 hybrid mice: relation to control of ethanol intake. Behavior Genetics. 40: 551-63. PMID 20364436 DOI: 10.1007/S10519-010-9357-X  0.715
2010 Ponomarev I, Rau V, Eger EI, Harris RA, Fanselow MS. Amygdala transcriptome and cellular mechanisms underlying stress-enhanced fear learning in a rat model of posttraumatic stress disorder. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 35: 1402-11. PMID 20147889 DOI: 10.1038/Npp.2010.10  0.552
2010 Gorini G, Ponomareva O, Shores KS, Person MD, Harris RA, Mayfield RD. Dynamin-1 co-associates with native mouse brain BKCa channels: proteomics analysis of synaptic protein complexes. Febs Letters. 584: 845-51. PMID 20114047 DOI: 10.1016/J.Febslet.2009.12.061  0.759
2010 McCracken LM, Trudell JR, Goldstein BE, Harris RA, Mihic SJ. Zinc enhances ethanol modulation of the alpha1 glycine receptor. Neuropharmacology. 58: 676-81. PMID 19913039 DOI: 10.1016/J.Neuropharm.2009.11.001  0.828
2010 Blednov YA, Ozburn AR, Walker D, Ahmed S, Belknap JK, Harris RA. Hybrid mice as genetic models of high alcohol consumption. Behavior Genetics. 40: 93-110. PMID 19798565 DOI: 10.1007/S10519-009-9298-4  0.736
2009 Etheridge N, Lewohl JM, Mayfield RD, Harris RA, Dodd PR. Synaptic proteome changes in the superior frontal gyrus and occipital cortex of the alcoholic brain. Proteomics. Clinical Applications. 3: 730-742. PMID 19924264 DOI: 10.1002/Prca.200800202  0.788
2009 Mayfield RD, Harris RA. Gene expression profiling in blood: new diagnostics in alcoholism and addiction? Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 34: 250-1. PMID 19079075 DOI: 10.1038/Npp.2008.162  0.771
2008 Horishita T, Eger EI, Harris RA. The effects of volatile aromatic anesthetics on voltage-gated Na+ channels expressed in Xenopus oocytes. Anesthesia and Analgesia. 107: 1579-86. PMID 18931215 DOI: 10.1213/Ane.0B013E318184B966  0.309
2008 Jenkins A, Lobo IA, Gong D, Trudell JR, Solt K, Harris RA, Eger EI. General anesthetics have additive actions on three ligand gated ion channels. Anesthesia and Analgesia. 107: 486-93. PMID 18633027 DOI: 10.1213/Ane.0B013E31817B70C1  0.796
2008 Harris RA, Trudell JR, Mihic SJ. Ethanol's molecular targets. Science Signaling. 1: re7. PMID 18632551 DOI: 10.1126/Scisignal.128Re7  0.688
2008 Ozburn AR, Harris RA, Blednov YA. Wheel running, voluntary ethanol consumption, and hedonic substitution. Alcohol (Fayetteville, N.Y.). 42: 417-24. PMID 18579336 DOI: 10.1016/J.Alcohol.2008.04.006  0.728
2008 Horishita T, Harris RA. n-Alcohols inhibit voltage-gated Na+ channels expressed in Xenopus oocytes. The Journal of Pharmacology and Experimental Therapeutics. 326: 270-7. PMID 18434586 DOI: 10.1124/Jpet.108.138370  0.432
2008 Lobo IA, Harris RA. GABA(A) receptors and alcohol. Pharmacology, Biochemistry, and Behavior. 90: 90-4. PMID 18423561 DOI: 10.1016/J.Pbb.2008.03.006  0.85
2008 Blednov YA, Harris RA. Metabotropic glutamate receptor 5 (mGluR5) regulation of ethanol sedation, dependence and consumption: relationship to acamprosate actions. The International Journal of Neuropsychopharmacology / Official Scientific Journal of the Collegium Internationale Neuropsychopharmacologicum (Cinp). 11: 775-93. PMID 18377703 DOI: 10.1017/S1461145708008584  0.49
2008 Mayfield RD, Harris RA, Schuckit MA. Genetic factors influencing alcohol dependence. British Journal of Pharmacology. 154: 275-87. PMID 18362899 DOI: 10.1038/Bjp.2008.88  0.755
2008 Reilly MT, Lobo IA, McCracken LM, Borghese CM, Gong D, Horishita T, Harris RA. Effects of acamprosate on neuronal receptors and ion channels expressed in Xenopus oocytes. Alcoholism, Clinical and Experimental Research. 32: 188-96. PMID 18226119 DOI: 10.1111/J.1530-0277.2007.00569.X  0.812
2008 Lobo IA, Harris RA, Trudell JR. Cross-linking of sites involved with alcohol action between transmembrane segments 1 and 3 of the glycine receptor following activation. Journal of Neurochemistry. 104: 1649-62. PMID 18036150 DOI: 10.1111/J.1471-4159.2007.05090.X  0.815
2007 Okvist A, Johansson S, Kuzmin A, Bazov I, Merino-Martinez R, Ponomarev I, Mayfield RD, Harris RA, Sheedy D, Garrick T, Harper C, Hurd YL, Terenius L, Ekström TJ, Bakalkin G, et al. Neuroadaptations in human chronic alcoholics: dysregulation of the NF-kappaB system. Plos One. 2: e930. PMID 17895971 DOI: 10.1371/Journal.Pone.0000930  0.809
2007 Liu J, Lewohl JM, Harris RA, Dodd PR, Mayfield RD. Altered gene expression profiles in the frontal cortex of cirrhotic alcoholics. Alcoholism, Clinical and Experimental Research. 31: 1460-6. PMID 17625000 DOI: 10.1111/J.1530-0277.2007.00444.X  0.829
2007 Borghese CM, Harris RA. Studies of ethanol actions on recombinant delta-containing gamma-aminobutyric acid type A receptors yield contradictory results. Alcohol (Fayetteville, N.Y.). 41: 155-62. PMID 17521845 DOI: 10.1016/J.Alcohol.2007.03.006  0.444
2007 Sonner JM, Werner DF, Elsen FP, Xing Y, Liao M, Harris RA, Harrison NL, Fanselow MS, Eger EI, Homanics GE. Effect of isoflurane and other potent inhaled anesthetics on minimum alveolar concentration, learning, and the righting reflex in mice engineered to express alpha1 gamma-aminobutyric acid type A receptors unresponsive to isoflurane. Anesthesiology. 106: 107-13. PMID 17197852 DOI: 10.1097/00000542-200701000-00019  0.331
2007 Blednov YA, Cravatt BF, Boehm SL, Walker D, Harris RA. Role of endocannabinoids in alcohol consumption and intoxication: studies of mice lacking fatty acid amide hydrolase. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 32: 1570-82. PMID 17164820 DOI: 10.1038/Sj.Npp.1301274  0.717
2007 Maiya R, Ponomarev I, Linse KD, Harris RA, Mayfield RD. Defining the dopamine transporter proteome by convergent biochemical and in silico analyses. Genes, Brain, and Behavior. 6: 97-106. PMID 16643512 DOI: 10.1111/J.1601-183X.2006.00236.X  0.767
2006 Blednov YA, Walker D, Martinez M, Harris RA. Reduced alcohol consumption in mice lacking preprodynorphin. Alcohol (Fayetteville, N.Y.). 40: 73-86. PMID 17307643 DOI: 10.1016/J.Alcohol.2006.12.002  0.477
2006 Boehm SL, Ponomarev I, Blednov YA, Harris RA. From gene to behavior and back again: new perspectives on GABAA receptor subunit selectivity of alcohol actions. Advances in Pharmacology (San Diego, Calif.). 54: 171-203. PMID 17175815 DOI: 10.1016/S1054-3589(06)54008-6  0.795
2006 Crabbe JC, Phillips TJ, Harris RA, Arends MA, Koob GF. Alcohol-related genes: contributions from studies with genetically engineered mice. Addiction Biology. 11: 195-269. PMID 16961758 DOI: 10.1111/J.1369-1600.2006.00038.X  0.683
2006 Krystal JH, Staley J, Mason G, Petrakis IL, Kaufman J, Harris RA, Gelernter J, Lappalainen J. Gamma-aminobutyric acid type A receptors and alcoholism: intoxication, dependence, vulnerability, and treatment. Archives of General Psychiatry. 63: 957-68. PMID 16952998 DOI: 10.1001/Archpsyc.63.9.957  0.459
2006 Borghese CM, Werner DF, Topf N, Baron NV, Henderson LA, Boehm SL, Blednov YA, Saad A, Dai S, Pearce RA, Harris RA, Homanics GE, Harrison NL. An isoflurane- and alcohol-insensitive mutant GABA(A) receptor alpha(1) subunit with near-normal apparent affinity for GABA: characterization in heterologous systems and production of knockin mice. The Journal of Pharmacology and Experimental Therapeutics. 319: 208-18. PMID 16807363 DOI: 10.1124/Jpet.106.104406  0.677
2006 Werner DF, Blednov YA, Ariwodola OJ, Silberman Y, Logan E, Berry RB, Borghese CM, Matthews DB, Weiner JL, Harrison NL, Harris RA, Homanics GE. Knockin mice with ethanol-insensitive alpha1-containing gamma-aminobutyric acid type A receptors display selective alterations in behavioral responses to ethanol. The Journal of Pharmacology and Experimental Therapeutics. 319: 219-27. PMID 16785315 DOI: 10.1124/Jpet.106.106161  0.445
2006 Boehm SL, Homanics GE, Blednov YA, Harris RA. delta-Subunit containing GABAA receptor knockout mice are less sensitive to the actions of 4,5,6,7-tetrahydroisoxazolo-[5,4-c]pyridin-3-ol. European Journal of Pharmacology. 541: 158-62. PMID 16777089 DOI: 10.1016/J.Ejphar.2006.02.054  0.676
2006 Ponomarev I, Maiya R, Harnett MT, Schafer GL, Ryabinin AE, Blednov YA, Morikawa H, Boehm SL, Homanics GE, Berman AE, Berman A, Lodowski KH, Bergeson SE, Harris RA. Transcriptional signatures of cellular plasticity in mice lacking the alpha1 subunit of GABAA receptors. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 26: 5673-83. PMID 16723524 DOI: 10.1523/Jneurosci.0860-06.2006  0.798
2006 Won A, Oh I, Liao M, Sonner JM, Harris RA, Laster MJ, Brosnan R, Trudell JR, Eger EI. The minimum alveolar anesthetic concentration of 2-, 3-, and 4-alcohols and ketones in rats: relevance to anesthetic mechanisms. Anesthesia and Analgesia. 102: 1419-26. PMID 16632820 DOI: 10.1213/01.Ane.0000204258.00676.98  0.379
2006 Ogata J, Shiraishi M, Namba T, Smothers CT, Woodward JJ, Harris RA. Effects of anesthetics on mutant N-methyl-D-aspartate receptors expressed in Xenopus oocytes. The Journal of Pharmacology and Experimental Therapeutics. 318: 434-43. PMID 16622040 DOI: 10.1124/Jpet.106.101691  0.382
2006 Mulligan MK, Ponomarev I, Hitzemann RJ, Belknap JK, Tabakoff B, Harris RA, Crabbe JC, Blednov YA, Grahame NJ, Phillips TJ, Finn DA, Hoffman PL, Iyer VR, Koob GF, Bergeson SE. Toward understanding the genetics of alcohol drinking through transcriptome meta-analysis. Proceedings of the National Academy of Sciences of the United States of America. 103: 6368-73. PMID 16618939 DOI: 10.1073/Pnas.0510188103  0.837
2006 Jung S, Harris RA. Sites in TM2 and 3 are critical for alcohol-induced conformational changes in GABA receptors. Journal of Neurochemistry. 96: 885-92. PMID 16405501 DOI: 10.1111/J.1471-4159.2005.03617.X  0.708
2006 Liu J, Lewohl JM, Harris RA, Iyer VR, Dodd PR, Randall PK, Mayfield RD. Patterns of gene expression in the frontal cortex discriminate alcoholic from nonalcoholic individuals. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 31: 1574-82. PMID 16292326 DOI: 10.1038/Sj.Npp.1300947  0.831
2006 Borghese CM, Stórustovu Sí, Ebert B, Herd MB, Belelli D, Lambert JJ, Marshall G, Wafford KA, Harris RA. The delta subunit of gamma-aminobutyric acid type A receptors does not confer sensitivity to low concentrations of ethanol. The Journal of Pharmacology and Experimental Therapeutics. 316: 1360-8. PMID 16272217 DOI: 10.1124/Jpet.105.092452  0.34
2006 Lobo IA, Trudell JR, Harris RA. Accessibility to residues in transmembrane segment four of the glycine receptor. Neuropharmacology. 50: 174-81. PMID 16225893 DOI: 10.1016/J.Neuropharm.2005.08.017  0.823
2006 Dodd PR, Tannenberg RK, Buckley ST, Eckert AL, Innes DJ, Mayfield RD, Harris RA. Interactions between serotonergic genotype and amino acid transmitter receptor expression in human alcoholics Alcoholism: Clinical and Experimental Research. 30. DOI: 10.1111/J.1530-0277.2006.00197.X  0.8
2006 Boehm SL, Ponomarev I, Blednov YA, Harris RA. From Gene to Behavior and Back Again: New Perspectives on GABAA Receptor Subunit Selectivity of Alcohol Actions1 Advances in Pharmacology. 54: 171-203. DOI: 10.1016/S1054-3589(06)54008-6  0.778
2005 Blednov YA, Metten P, Finn DA, Rhodes JS, Bergeson SE, Harris RA, Crabbe JC. Hybrid C57BL/6J x FVB/NJ mice drink more alcohol than do C57BL/6J mice. Alcoholism, Clinical and Experimental Research. 29: 1949-58. PMID 16340451 DOI: 10.1097/01.Alc.0000187605.91468.17  0.552
2005 Dani JA, Harris RA. Nicotine addiction and comorbidity with alcohol abuse and mental illness. Nature Neuroscience. 8: 1465-70. PMID 16251989 DOI: 10.1038/Nn1580  0.3
2005 Lobo IA, Harris RA. Sites of alcohol and volatile anesthetic action on glycine receptors. International Review of Neurobiology. 65: 53-87. PMID 16140053 DOI: 10.1016/S0074-7742(04)65003-3  0.832
2005 Blednov YA, Bergeson SE, Walker D, Ferreira VM, Kuziel WA, Harris RA. Perturbation of chemokine networks by gene deletion alters the reinforcing actions of ethanol. Behavioural Brain Research. 165: 110-25. PMID 16105698 DOI: 10.1016/J.Bbr.2005.06.026  0.45
2005 Alling C, Chick JD, Anton R, Mayfield RD, Salaspuro M, Helander A, Harris RA. Revealing alcohol abuse: to ask or to test? Alcoholism, Clinical and Experimental Research. 29: 1257-63. PMID 16088981 DOI: 10.1097/01.Alc.0000171489.55856.A5  0.746
2005 Liao M, Sonner JM, Jurd R, Rudolph U, Borghese CM, Harris RA, Laster MJ, Eger EI. Beta3-containing gamma-aminobutyric acidA receptors are not major targets for the amnesic and immobilizing actions of isoflurane. Anesthesia and Analgesia. 101: 412-8, table of cont. PMID 16037154 DOI: 10.1213/01.Ane.0000154196.86587.35  0.345
2005 Jung S, Akabas MH, Harris RA. Functional and structural analysis of the GABAA receptor alpha 1 subunit during channel gating and alcohol modulation. The Journal of Biological Chemistry. 280: 308-16. PMID 15522868 DOI: 10.1074/Jbc.M409871200  0.679
2004 Blednov YA, Walker D, Osterndorf-Kahanek E, Harris RA. Mice lacking metabotropic glutamate receptor 4 do not show the motor stimulatory effect of ethanol. Alcohol (Fayetteville, N.Y.). 34: 251-9. PMID 15902920 DOI: 10.1016/J.Alcohol.2004.10.003  0.396
2004 Blednov YA, Walker D, Harris RA. Blockade of the leptin-sensitive pathway markedly reduces alcohol consumption in mice. Alcoholism, Clinical and Experimental Research. 28: 1683-92. PMID 15547455 DOI: 10.1097/01.Alc.0000145790.60216.C8  0.48
2004 Ponomarev I, Schafer GL, Blednov YA, Williams RW, Iyer VR, Harris RA. Convergent analysis of cDNA and short oligomer microarrays, mouse null mutants and bioinformatics resources to study complex traits. Genes, Brain, and Behavior. 3: 360-8. PMID 15544578 DOI: 10.1111/J.1601-183X.2004.00088.X  0.647
2004 Lewohl JM, Van Dyk DD, Craft GE, Innes DJ, Mayfield RD, Cobon G, Harris RA, Dodd PR. The application of proteomics to the human alcoholic brain. Annals of the New York Academy of Sciences. 1025: 14-26. PMID 15542695 DOI: 10.1196/Annals.1316.002  0.785
2004 Boehm SL, Peden L, Jennings AW, Kojima N, Harris RA, Blednov YA. Over-expression of the fyn-kinase gene reduces hypnotic sensitivity to ethanol in mice. Neuroscience Letters. 372: 6-11. PMID 15531078 DOI: 10.1016/J.Neulet.2004.08.028  0.696
2004 Boehm SL, Ponomarev I, Jennings AW, Whiting PJ, Rosahl TW, Garrett EM, Blednov YA, Harris RA. gamma-Aminobutyric acid A receptor subunit mutant mice: new perspectives on alcohol actions. Biochemical Pharmacology. 68: 1581-602. PMID 15451402 DOI: 10.1016/J.Bcp.2004.07.023  0.795
2004 Liu J, Lewohl JM, Dodd PR, Randall PK, Harris RA, Mayfield RD. Gene expression profiling of individual cases reveals consistent transcriptional changes in alcoholic human brain. Journal of Neurochemistry. 90: 1050-8. PMID 15312160 DOI: 10.1111/J.1471-4159.2004.02570.X  0.822
2004 Lobo IA, Trudell JR, Harris RA. Cross-linking of glycine receptor transmembrane segments two and three alters coupling of ligand binding with channel opening. Journal of Neurochemistry. 90: 962-9. PMID 15287902 DOI: 10.1111/J.1471-4159.2004.02561.X  0.806
2004 Zhang Y, Sonner JM, Eger EI, Stabernack CR, Laster MJ, Raines DE, Harris RA. Gamma-aminobutyric acidA receptors do not mediate the immobility produced by isoflurane. Anesthesia and Analgesia. 99: 85-90. PMID 15281509 DOI: 10.1213/01.Ane.0000118108.64886.42  0.333
2004 Lobo IA, Mascia MP, Trudell JR, Harris RA. Channel gating of the glycine receptor changes accessibility to residues implicated in receptor potentiation by alcohols and anesthetics. The Journal of Biological Chemistry. 279: 33919-27. PMID 15169788 DOI: 10.1074/Jbc.M313941200  0.81
2004 Shiraishi M, Harris RA. Effects of Alcohols and Anesthetics on Recombinant Voltage-Gated Na+ Channels Journal of Pharmacology and Experimental Therapeutics. 309: 987-994. PMID 14978193 DOI: 10.1124/Jpet.103.064063  0.337
2004 Boehm SL, Peden L, Harris RA, Blednov YA. Deletion of the fyn-kinase gene alters sensitivity to GABAergic drugs: dependence on beta2/beta3 GABAA receptor subunits. The Journal of Pharmacology and Experimental Therapeutics. 309: 1154-9. PMID 14764659 DOI: 10.1124/Jpet.103.064444  0.68
2004 Harris RA, Mihic SJ. Alcohol and inhibitory receptors: unexpected specificity from a nonspecific drug. Proceedings of the National Academy of Sciences of the United States of America. 101: 2-3. PMID 14695895 DOI: 10.1073/pnas.0307281101  0.693
2003 Mayfield RD, Liu J, Randall PK, Lewohl JM, Dodd PR, Harris RA. Methods for the identification of differentially expressed genes in human post-mortem brain. Methods (San Diego, Calif.). 31: 301-5. PMID 14597314 DOI: 10.1016/S1046-2023(03)00159-2  0.773
2003 Borghese CM, Henderson LA, Bleck V, Trudell JR, Harris RA. Sites of excitatory and inhibitory actions of alcohols on neuronal alpha2beta4 nicotinic acetylcholine receptors. The Journal of Pharmacology and Experimental Therapeutics. 307: 42-52. PMID 14500778 DOI: 10.1124/Jpet.102.053710  0.448
2003 Borghese CM, Wang L, Bleck V, Harris RA. Mutation in neuronal nicotinic acetylcholine receptors expressed in Xenopus oocytes blocks ethanol action. Addiction Biology. 8: 313-8. PMID 13129833 DOI: 10.1080/13556210310001602220  0.437
2003 Findlay GS, Phelan R, Roberts MT, Homanics GE, Bergeson SE, Lopreato GF, Mihic SJ, Blednov YA, Harris RA. Glycine receptor knock-in mice and hyperekplexia-like phenotypes: comparisons with the null mutant. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 23: 8051-9. PMID 12954867 DOI: 10.1523/Jneurosci.23-22-08051.2003  0.748
2003 Boehm SL, Peden L, Chang R, Harris RA, Blednov YA. Deletion of the fyn-kinase gene alters behavioral sensitivity to ethanol. Alcoholism, Clinical and Experimental Research. 27: 1033-40. PMID 12878908 DOI: 10.1097/01.Alc.0000075822.80583.71  0.676
2003 Zhang Y, Laster MJ, Hara K, Harris RA, Eger EI, Stabernack CR, Sonner JM. Glycine receptors mediate part of the immobility produced by inhaled anesthetics. Anesthesia and Analgesia. 96: 97-101, table of con. PMID 12505932 DOI: 10.1097/00000539-200301000-00021  0.335
2003 Borghese CM, Ali DN, Bleck V, Harris RA. Acetylcholine and alcohol sensitivity of neuronal nicotinic acetylcholine receptors: mutations in transmembrane domains. Alcoholism, Clinical and Experimental Research. 26: 1764-72. PMID 12500099 DOI: 10.1097/01.ALC.0000042012.58231.D9  0.326
2003 Blednov YA, Jung S, Alva H, Wallace D, Rosahl T, Whiting PJ, Harris RA. Deletion of the alpha1 or beta2 subunit of GABAA receptors reduces actions of alcohol and other drugs. The Journal of Pharmacology and Experimental Therapeutics. 304: 30-6. PMID 12490572 DOI: 10.1124/Jpet.102.042960  0.358
2002 Hara K, Eger EI, Laster MJ, Harris RA. Nonhalogenated alkanes cyclopropane and butane affect neurotransmitter-gated ion channel and G-protein-coupled receptors: differential actions on GABAA and glycine receptors. Anesthesiology. 97: 1512-20. PMID 12459679 DOI: 10.1097/00000542-200212000-00025  0.339
2002 Harris RA, Morrisett RA. Two-shot cocktail: adenosine, dopamine and a twist of beta gamma. Nature Medicine. 8: 777-9. PMID 12152026 DOI: 10.1038/Nm0802-777  0.324
2002 Maiya R, Buck KJ, Harris RA, Mayfield RD. Ethanol-sensitive sites on the human dopamine transporter. The Journal of Biological Chemistry. 277: 30724-9. PMID 12070173 DOI: 10.1074/Jbc.M204914200  0.794
2002 Mayfield RD, Lewohl JM, Dodd PR, Herlihy A, Liu J, Harris RA. Patterns of gene expression are altered in the frontal and motor cortices of human alcoholics. Journal of Neurochemistry. 81: 802-13. PMID 12065639 DOI: 10.1046/J.1471-4159.2002.00860.X  0.826
2002 Findlay GS, Wick MJ, Mascia MP, Wallace D, Miller GW, Harris RA, Blednov YA. Transgenic expression of a mutant glycine receptor decreases alcohol sensitivity of mice. The Journal of Pharmacology and Experimental Therapeutics. 300: 526-34. PMID 11805213 DOI: 10.1124/Jpet.300.2.526  0.714
2002 Borghese CM, Harris RA. Anesthetic-induced immobility: neuronal nicotinic acetylcholine receptors are no longer in the picture. Anesthesia & Analgesia. 95: 509-511. DOI: 10.1213/00000539-200209000-00001  0.33
2002 Borghese CM, Ali DN, Bleck V, Harris RA. Acetylcholine and alcohol sensitivity of neuronal nicotinic acetylcholine receptors: mutations in transmembrane domains. Alcoholism: Clinical and Experimental Research. 26: 1764-1772. DOI: 10.1111/J.1530-0277.2002.Tb02482.X  0.425
2001 Zhang Y, Stabernack CR, Dutton R, Sonner J, Trudell JR, Mihic SJ, Yamakura T, Harris RA, Gong D, Eger EI. Luciferase as a model for the site of inhaled anesthetic action. Anesthesia and Analgesia. 93: 1246-52. PMID 11682406 DOI: 10.1097/00000539-200111000-00041  0.622
2001 Hara K, Lewohl JM, Yamakura T, Harris RA. Mutational analysis of ethanol interactions with G-protein-coupled inwardly rectifying potassium channels. Alcohol. 24: 5-8. PMID 11524176 DOI: 10.1016/S0741-8329(01)00134-3  0.337
2001 Yamakura T, Lewohl JM, Harris RA. Differential effects of general anesthetics on G protein-coupled inwardly rectifying and other potassium channels. Anesthesiology. 95: 144-153. PMID 11465552 DOI: 10.1097/00000542-200107000-00025  0.336
2001 Ueno S, Harris RA, Messing RO, Sanchez-Perez AM, Hodge CW, McMahon T, Wang D, Mehmert KK, Kelley SP, Haywood A, Olive MF, Buck KJ, Hood HM, Blednov Y, Findlay G, et al. Alcohol actions on GABA(A) receptors: from protein structure to mouse behavior. Alcoholism, Clinical and Experimental Research. 25: 76S-81S. PMID 11391054 DOI: 10.1111/J.1530-0277.2001.Tb02378.X  0.733
2001 Findlay GS, Ueno S, Harrison NL, Harris RA. Allosteric modulation in spontaneously active mutant gamma-aminobutyric acidA receptors. Neuroscience Letters. 305: 77-80. PMID 11356312 DOI: 10.1016/S0304-3940(01)01646-9  0.358
2001 Godden EL, Harris RA, Dunwiddie TV. Correlation between molecular volume and effects of n-alcohols on human neuronal nicotinic acetylcholine receptors expressed in Xenopus oocytes. The Journal of Pharmacology and Experimental Therapeutics. 296: 716-22. PMID 11181898  0.391
2001 Lewohl JM, Dodd PR, Mayfield RD, Harris RA. Application of DNA microarrays to study human alcoholism. Journal of Biomedical Science. 8: 28-36. PMID 11173973 DOI: 10.1007/Bf02255968  0.797
2000 Lewohl JM, Wang L, Miles MF, Zhang L, Dodd PR, Harris RA. Gene expression in human alcoholism: microarray analysis of frontal cortex. Alcoholism, Clinical and Experimental Research. 24: 1873-82. PMID 11141048  0.303
2000 Zhang Y, Trudell JR, Mascia MP, Laster MJ, Gong DH, Harris RA, Eger EI. The anesthetic potencies of alkanethiols for rats: relevance to theories of narcosis. Anesthesia and Analgesia. 91: 1294-9. PMID 11049925 DOI: 10.1213/00000539-200011000-00045  0.617
2000 Mascia MP, Gong DH, Eger EI, Harris RA. The anesthetic potency of propanol and butanol versus propanethiol and butanethiol in alpha1 wild type and alpha1(S267Q) glycine receptors. Anesthesia and Analgesia. 91: 1289-93. PMID 11049924  0.678
2000 Findlay GS, Ueno S, Harrison NL, Harris RA. Allosteric modulation in spontaneously active mutant gamma-aminobutyric acid(A) receptors [corrected]. Neuroscience Letters. 293: 155-8. PMID 11036184 DOI: 10.1016/S0304-3940(00)01503-2  0.357
2000 Yamakura T, Harris RA. Effects of gaseous anesthetics nitrous oxide and xenon on ligand-gated ion channels: Comparison with isoflurane and ethanol Anesthesiology. 93: 1095-1101. PMID 11020766 DOI: 10.1097/00000542-200010000-00034  0.317
2000 Yamakura T, Borghese C, Harris RA. A transmembrane site determines sensitivity of neuronal nicotinic acetylcholine receptors to general anesthetics. Journal of Biological Chemistry. 275: 40879-40886. PMID 11020384 DOI: 10.1074/Jbc.M005771200  0.306
2000 Ueno S, Lin A, Nikolaeva N, Trudell JR, Mihic SJ, Harris RA, Harrison NL. Tryptophan scanning mutagenesis in TM2 of the GABA(A) receptor alpha subunit: effects on channel gating and regulation by ethanol. British Journal of Pharmacology. 131: 296-302. PMID 10991923 DOI: 10.1038/Sj.Bjp.0703504  0.685
2000 Baer K, Essrich C, Balsiger S, Wick MJ, Harris RA, Fritschy JM, Lüscher B. Rescue of γ2 subunit-deficient mice by transgenic overexpression of the GABA(A) receptor γ2S or γ2L subunit isoforms European Journal of Neuroscience. 12: 2639-2643. PMID 10947838 DOI: 10.1046/J.1460-9568.2000.00159.X  0.353
2000 Wick MJ, Radcliffe RA, Bowers BJ, Mascia MP, Lüscher B, Harris RA, Wehner JM. Behavioural changes produced by transgenic overexpression of gamma2L and gamma2S subunits of the GABAA receptor. The European Journal of Neuroscience. 12: 2634-8. PMID 10947837 DOI: 10.1046/J.1460-9568.2000.00160.X  0.749
2000 Mascia MP, Trudell JR, Harris RA. Specific binding sites for alcohols and anesthetics on ligand-gated ion channels. Proceedings of the National Academy of Sciences of the United States of America. 97: 9305-10. PMID 10908659 DOI: 10.1073/Pnas.160128797  0.74
2000 Yamakura T, Chavez-Noriega LE, Harris RA. Subunit-dependent inhibition of human neuronal nicotinic acetylcholine receptors and other ligand-gated ion channels by dissociative anesthetics ketamine and dizocilpine. Anesthesiology. 92: 1144-1153. PMID 10754635 DOI: 10.1097/00000542-200004000-00033  0.337
2000 Mascia MP, Gong DH, Eger EI, Harris RA. The Anesthetic Potency of Propanol and Butanol Versus Propanethiol and Butanethiol in α1 Wild Type and α1(s267q) Glycine Receptors Anesthesia & Analgesia. 91: 1289-1293. DOI: 10.1213/00000539-200011000-00044  0.706
2000 Lewohl JM, Wang L, Miles MF, Zhang L, Dodd PR, Harris RA. Gene Expression in Human Alcoholism: Microarray Analysis of Frontal Cortex Alcoholism: Clinical and Experimental Research. 24: 1873-1882. DOI: 10.1111/J.1530-0277.2000.Tb01993.X  0.651
1999 Lewohl JM, Wilson WR, Mayfield RD, Brozowski SJ, Morrisett RA, Harris RA. G-protein-coupled inwardly rectifying potassium channels are targets of alcohol action. Nature Neuroscience. 2: 1084-90. PMID 10570485 DOI: 10.1038/16012  0.766
1999 Yamakura T, Mihic SJ, Harris RA. Amino acid volume and hydropathy of a transmembrane site determine glycine and anesthetic sensitivity of glycine receptors. The Journal of Biological Chemistry. 274: 23006-12. PMID 10438467 DOI: 10.1074/Jbc.274.33.23006  0.645
1999 Ueno S, Wick MJ, Ye Q, Harrison NL, Harris RA. Subunit mutations affect ethanol actions on GABA(A) receptors expressed in Xenopus oocytes. British Journal of Pharmacology. 127: 377-82. PMID 10385236 DOI: 10.1038/Sj.Bjp.0702563  0.38
1999 Cardoso RA, Brozowski SJ, Chavez-Noriega LE, Harpold M, Valenzuela CF, Harris RA. Effects of ethanol on recombinant human neuronal nicotinic acetylcholine receptors expressed in Xenopus oocytes. The Journal of Pharmacology and Experimental Therapeutics. 289: 774-80. PMID 10215652  0.348
1999 Ueno S, Trudell JR, Eger EI, Harris RA. Actions of fluorinated alkanols on GABA(A) receptors: relevance to theories of narcosis. Anesthesia and Analgesia. 88: 877-83. PMID 10195541 DOI: 10.1097/00000539-199904000-00036  0.307
1999 Ueno S, Trudell JR, Eger EI, Harris RA. Actions of Fluorinated Alkanols on GABAA Receptors Anesthesia & Analgesia. 88: 877-883. DOI: 10.1213/00000539-199904000-00036  0.301
1999 Harris RA. Ethanol Actions on Multiple Ion Channels: Which Are Important? Alcoholism: Clinical and Experimental Research. 23: 1563-1570. DOI: 10.1111/J.1530-0277.1999.Tb04045.X  0.399
1998 Chandler LJ, Harris RA, Crews FT. Ethanol tolerance and synaptic plasticity. Trends in Pharmacological Sciences. 19: 491-5. PMID 9871410 DOI: 10.1016/S0165-6147(98)01268-1  0.38
1998 Mascia MP, Wick MJ, Martinez LD, Harris RA. Enhancement of glycine receptor function by ethanol: role of phosphorylation. British Journal of Pharmacology. 125: 263-70. PMID 9786497 DOI: 10.1038/Sj.Bjp.0702054  0.719
1998 Valenzuela CF, Bhave S, Hoffman P, Harris RA. Acute effects of ethanol on pharmacologically isolated kainate receptors in cerebellar granule neurons: comparison with NMDA and AMPA receptors. Journal of Neurochemistry. 71: 1777-80. PMID 9751216 DOI: 10.1046/J.1471-4159.1998.71041777.X  0.37
1998 Valenzuela CF, Cardoso RA, Wick MJ, Weiner JL, Dunwiddie TV, Harris RA. Effects of ethanol on recombinant glycine receptors expressed in mammalian cell lines. Alcoholism, Clinical and Experimental Research. 22: 1132-6. PMID 9726286 DOI: 10.1111/J.1530-0277.1998.Tb03712.X  0.385
1998 Harris RA, Mihic SJ, Valenzuela CF. Alcohol and benzodiazepines: recent mechanistic studies. Drug and Alcohol Dependence. 51: 155-64. PMID 9716937 DOI: 10.1016/S0376-8716(98)00073-8  0.628
1998 Wick MJ, Mihic SJ, Ueno S, Mascia MP, Trudell JR, Brozowski SJ, Ye Q, Harrison NL, Harris RA. Mutations of gamma-aminobutyric acid and glycine receptors change alcohol cutoff: evidence for an alcohol receptor? Proceedings of the National Academy of Sciences of the United States of America. 95: 6504-9. PMID 9600996 DOI: 10.1073/Pnas.95.11.6504  0.831
1998 Ye Q, Koltchine VV, Mihic SJ, Mascia MP, Wick MJ, Finn SE, Harrison NL, Harris RA. Enhancement of glycine receptor function by ethanol is inversely correlated with molecular volume at position alpha267. The Journal of Biological Chemistry. 273: 3314-9. PMID 9452448 DOI: 10.1074/Jbc.273.6.3314  0.819
1998 Minami K, Gereau RW, Minami M, Heinemann SF, Harris RA. Effects of ethanol and anesthetics on type 1 and 5 metabotropic glutamate receptors expressed in Xenopus laevis oocytes. Molecular Pharmacology. 53: 148-56. PMID 9443943 DOI: 10.1124/Mol.53.1.148  0.372
1997 Mihic SJ, Harris RA. GABA and the GABAA receptor. Alcohol Health and Research World. 21: 127-31. PMID 15704348  0.713
1997 Minami K, Vanderah TW, Minami M, Harris RA. Inhibitory effects of anesthetics and ethanol on muscarinic receptors expressed in Xenopus oocytes. European Journal of Pharmacology. 339: 237-44. PMID 9473141 DOI: 10.1016/S0014-2999(97)01354-X  0.353
1997 Mihic SJ, Ye Q, Wick MJ, Koltchine VV, Krasowski MD, Finn SE, Mascia MP, Valenzuela CF, Hanson KK, Greenblatt EP, Harris RA, Harrison NL. Sites of alcohol and volatile anaesthetic action on GABA(A) and glycine receptors. Nature. 389: 385-9. PMID 9311780 DOI: 10.1038/38738  0.818
1997 Minami K, Minami M, Harris RA. Inhibition of 5-hydroxytryptamine type 2A receptor-induced currents by n-alcohols and anesthetics. The Journal of Pharmacology and Experimental Therapeutics. 281: 1136-43. PMID 9190846  0.316
1997 Harris RA, Mihic SJ, Brozowski S, Hadingham K, Whiting PJ. Ethanol, flunitrazepam, and pentobarbital modulation of GABAA receptors expressed in mammalian cells and Xenopus oocytes. Alcoholism, Clinical and Experimental Research. 21: 444-51. PMID 9161604  0.637
1997 Mascia MP, Bleck VG, Harris RA. Glycine receptors from long-sleep and short-sleep mice: genetic differences in drug sensitivity. Brain Research. Molecular Brain Research. 45: 169-72. PMID 9105687 DOI: 10.1016/S0169-328X(97)00008-9  0.67
1996 Harris RA. Transfected cells for study of alcohol actions on GABAA receptors Addiction Biology. 1: 157-163. PMID 12893475 DOI: 10.1080/1355621961000124776  0.438
1996 Mascia MP, Machu TK, Harris RA. Enhancement of homomeric glycine receptor function by long-chain alcohols and anaesthetics. British Journal of Pharmacology. 119: 1331-6. PMID 8968539 DOI: 10.1111/j.1476-5381.1996.tb16042.x  0.742
1996 Blednov YA, Bleck V, Harris RA. Measurement of glycine receptor function by radioactive chloride uptake Journal of Neuroscience Methods. 68: 253-257. PMID 8912198 DOI: 10.1016/0165-0270(96)00088-X  0.326
1996 Dildy-Mayfield JE, Mihic SJ, Liu Y, Deitrich RA, Harris RA. Actions of long chain alcohols on GABAA and glutamate receptors: relation to in vivo effects. British Journal of Pharmacology. 118: 378-84. PMID 8735641  0.713
1996 Mihic SJ, Harris RA. Robotic automation of Xenopus oocyte bath perfusion. Biotechniques. 20: 802-4. PMID 8723922  0.523
1996 Mascia MP, Mihic SJ, Valenzuela CF, Schofield PR, Harris RA. A single amino acid determines differences in ethanol actions on strychnine-sensitive glycine receptors. Molecular Pharmacology. 50: 402-6. PMID 8700149  0.775
1996 Deitrich RA, Harris RA. How much alcohol should I use in my experiments? Alcoholism: Clinical and Experimental Research. 20: 1-2. PMID 8651438 DOI: 10.1111/j.1530-0277.1996.tb01033.x  0.313
1996 Mihic SJ, Harris RA. Inhibition of rho1 receptor GABAergic currents by alcohols and volatile anesthetics. The Journal of Pharmacology and Experimental Therapeutics. 277: 411-6. PMID 8613949  0.669
1995 Klein RL, Mascia MP, Whiting PJ, Harris RA. GABAA receptor function and binding in stably transfected cells: chronic ethanol treatment. Alcoholism, Clinical and Experimental Research. 19: 1338-44. PMID 8561312 DOI: 10.1111/J.1530-0277.1995.Tb01622.X  0.723
1995 Sanna E, Garau F, Harris RA. Novel properties of homomeric beta 1 gamma-aminobutyric acid type A receptors: actions of the anesthetics propofol and pentobarbital. Molecular Pharmacology. 47: 213-7. PMID 7870027  0.518
1995 Harris RA, Proctor WR, McQuilkin SJ, Klein RL, Mascia MP, Whatley V, Whiting PJ, Dunwiddie TV. Ethanol increases GABAA responses in cells stably transfected with receptor subunits. Alcoholism, Clinical and Experimental Research. 19: 226-32. PMID 7771653 DOI: 10.1111/J.1530-0277.1995.Tb01496.X  0.723
1995 Mihic SJ, Sanna E, Whiting PJ, Harris RA. Pharmacology of recombinant GABAA receptors. Advances in Biochemical Psychopharmacology. 48: 17-40. PMID 7653324  0.708
1995 Sanna E, Mascia MP, Klein RL, Whiting PJ, Biggio G, Harris RA. Actions of the general anesthetic propofol on recombinant human GABAA receptors: influence of receptor subunits. The Journal of Pharmacology and Experimental Therapeutics. 274: 353-60. PMID 7616420  0.752
1995 Harris RA, Mihic SJ, Dildy-Mayfield JE, Machu TK. Actions of anesthetics on ligand-gated ion channels: role of receptor subunit composition. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 9: 1454-62. PMID 7589987 DOI: 10.1096/fasebj.9.14.7589987  0.625
1995 Klein RL, Mascia MP, Harkness PC, Hadingham KL, Whiting PJ, Harris RA. Regulation of allosteric coupling and function of stably expressed gamma-aminobutyric acid (GABA)A receptors by chronic treatment with GABAA and benzodiazepine agonists. The Journal of Pharmacology and Experimental Therapeutics. 274: 1484-92. PMID 7562525  0.688
1994 Avdulov NA, Wood WG, Harris RA. Effects of ethanol on structural parameters of rat brain membranes: relationship to genetic differences in ethanol sensitivity. Alcoholism: Clinical and Experimental Research. 18: 53-59. PMID 8198227 DOI: 10.1111/J.1530-0277.1994.Tb00880.X  0.338
1994 Sanna E, Dildy-Mayfield JE, Harris RA. Ethanol inhibits the function of 5-hydroxytryptamine type 1c and muscarinic M1 G protein-linked receptors in Xenopus oocytes expressing brain mRNA: role of protein kinase C. Molecular Pharmacology. 45: 1004-12. PMID 8190090  0.547
1994 Mihic SJ, Whatley VJ, McQuilkin SJ, Harris RA. beta-Lumicolchicine interacts with the benzodiazepine binding site to potentiate GABAA receptor-mediated currents. Journal of Neurochemistry. 62: 1790-4. PMID 8158128  0.615
1994 Mihic SJ, McQuilkin SJ, Eger EI, Ionescu P, Harris RA. Potentiation of gamma-aminobutyric acid type A receptor-mediated chloride currents by novel halogenated compounds correlates with their abilities to induce general anesthesia. Molecular Pharmacology. 46: 851-7. PMID 7969071  0.624
1994 Klein RL, Sanna E, McQuilkin SJ, Whiting PJ, Harris RA. Effects of 5-HT3 receptor antagonists on binding and function of mouse and human GABAA receptors. European Journal of Pharmacology. 268: 237-46. PMID 7957645 DOI: 10.1016/0922-4106(94)90194-5  0.526
1994 Mihic SJ, Whiting PJ, Harris RA. Anaesthetic concentrations of alcohols potentiate GABAA receptor-mediated currents: lack of subunit specificity. European Journal of Pharmacology. 268: 209-14. PMID 7957642 DOI: 10.1016/0922-4106(94)90190-2  0.655
1994 Whatley VJ, Mihic SJ, Allan AM, McQuilkin SJ, Harris RA. Gamma-aminobutyric acidA receptor function is inhibited by microtubule depolymerization. The Journal of Biological Chemistry. 269: 19546-52. PMID 7913471  0.639
1994 Mihic SJ, Whiting PJ, Klein RL, Wafford KA, Harris RA. A single amino acid of the human gamma-aminobutyric acid type A receptor gamma 2 subunit determines benzodiazepine efficacy. The Journal of Biological Chemistry. 269: 32768-73. PMID 7806498  0.643
1993 Sanna E, Harris RA. Recent developments in alcoholism:neuronal ion channels. Recent Developments in Alcoholism : An Official Publication of the American Medical Society On Alcoholism, the Research Society On Alcoholism, and the National Council On Alcoholism. 11: 169-86. PMID 7694329  0.532
1993 Lin L‐, Whiting P, Harris RA. Molecular determinants of general anesthetic action: role of GABAA receptor structure. Journal of Neurochemistry. 60: 1548-1553. PMID 7681105 DOI: 10.1111/J.1471-4159.1993.Tb03320.X  0.37
1992 Harris RA, Brodie MS, Dunwiddie TV. Possible substrates of ethanol reinforcement: GABA and dopamine. Annals of the New York Academy of Sciences. 654: 61-9. PMID 1321582 DOI: 10.1111/J.1749-6632.1992.Tb25956.X  0.313
1992 Samson HH, Harris RA. Neurobiology of alcohol abuse. Trends in Pharmacological Sciences. 13: 206-11. PMID 1306042 DOI: 10.1016/0165-6147(92)90065-E  0.49
1991 Harris RA. Mammalian Genetics in the Study of Alcohol and Anesthetic Actions Annals of the New York Academy of Sciences. 625: 508-514. PMID 2058902 DOI: 10.1111/J.1749-6632.1991.Tb33881.X  0.357
1991 Daniell LC, Harris RA. Effect of Chronic Ethanol Treatment and Selective Breeding for Sensitivity to Ethanol on Calcium Release Induced by Inositol Trisphosphate for Ethanol from Brain and Liver Microsomes Alcoholism: Clinical and Experimental Research. 15: 224-228. PMID 2058799 DOI: 10.1111/J.1530-0277.1991.Tb01860.X  0.328
1991 Buck KJ, Harris RA. Neuroadaptive responses to chronic ethanol. Alcoholism, Clinical and Experimental Research. 15: 460-70. PMID 1715134 DOI: 10.1111/J.1530-0277.1991.Tb00544.X  0.385
1991 Wafford KA, Burnett DM, Leidenheimer NJ, Burt DR, Wang JB, Kofuji P, Dunwiddie TV, Harris RA, Sikela JM. Ethanol sensitivity of the GABAA receptor expressed in Xenopus oocytes requires 8 amino acids contained in the gamma 2L subunit. Neuron. 7: 27-33. PMID 1712603 DOI: 10.1016/0896-6273(91)90071-7  0.349
1991 Buck KJ, McQuilkin SJ, Harris RA. Modulation of gamma-aminobutyric acidA receptor-operated chloride channels by benzodiazepine inverse agonists is related to genetic differences in ethanol withdrawal seizure severity. Journal of Neurochemistry. 57: 2100-5. PMID 1658234 DOI: 10.1111/J.1471-4159.1991.Tb06428.X  0.393
1991 Buck KJ, Hahner L, Sikela J, Harris RA. Chronic ethanol treatment alters brain levels of gamma-aminobutyric acidA receptor subunit mRNAs: relationship to genetic differences in ethanol withdrawal seizure severity. Journal of Neurochemistry. 57: 1452-5. PMID 1654394 DOI: 10.1111/J.1471-4159.1991.Tb08313.X  0.376
1991 Allan AM, Burnett D, Harris RA. Ethanol-induced changes in chloride flux are mediated by both GABA(A) and GABA(B) receptors Alcoholism: Clinical and Experimental Research. 15: 233-237. PMID 1647705 DOI: 10.1111/J.1530-0277.1991.Tb01862.X  0.369
1991 Buck KJ, Heim H, Harris RA. Reversal of alcohol dependence and tolerance by a single administration of flumazenil. The Journal of Pharmacology and Experimental Therapeutics. 257: 984-9. PMID 1646333  0.304
1990 Harris RA. Alcohol sensitivity [6] Nature. 348: 589. PMID 2174513  0.334
1990 Harris RA. Distinct actions of alcohols, barbiturates and benzodiazepines on GABA-activated chloride channels Alcohol. 7: 273-275. PMID 1691915 DOI: 10.1016/0741-8329(90)90017-7  0.408
1990 McQuilkin SJ, Harris RA. Factors affecting actions of ethanol on GABA-activated chloride channels Life Sciences. 46: 527-541. PMID 1689450 DOI: 10.1016/0024-3205(90)90009-G  0.354
1989 Buck KJ, Allan AM, Harris RA. Fluidization of brain membranes by A2C does not produce anesthesia and does not augment muscimol-stimulated 36Cl- influx. European Journal of Pharmacology. 160: 359-67. PMID 2714367 DOI: 10.1016/0014-2999(89)90091-5  0.398
1989 Lewin E, Peris J, Bleck V, Zahniser NR, Harris RA. Diazepam sensitizes mice to FG 7142 and reduces muscimol-stimulated 36Cl- flux. Pharmacology, Biochemistry, and Behavior. 33: 465-8. PMID 2479037 DOI: 10.1016/0091-3057(89)90531-5  0.316
1988 Feller DJ, Harris RA, Crabbe JC. Differences in GABA activity between ethanol withdrawal seizure prone and resistant mice. European Journal of Pharmacology. 157: 147-54. PMID 3224635 DOI: 10.1016/0014-2999(88)90377-9  0.545
1988 Harris RA, Allan AM. Neurochemistry of brain chloride channels: genetic variation in modulation by GABA agonists, alcohol and benzodiazepines Advances in Biochemical Psychopharmacology. 45: 189-198. PMID 2459919  0.308
1988 Allan AM, Gallaher EJ, Gionet SE, Harris RA. Genetic selection for benzodiazepine ataxia produces functional changes in the γ-aminobutyric acid receptor chloride channel complex Brain Research. 452: 118-126. PMID 2456824 DOI: 10.1016/0006-8993(88)90016-9  0.363
1988 Daniell LC, Harris RA. Effect of chronic ethanol treatment and selective breeding for hypnotic sensitivity to ethanol on intracellular ionized calcium concentrations in synaptosomes. Alcoholism: Clinical and Experimental Research. 12: 179-183. PMID 2450482 DOI: 10.1111/J.1530-0277.1988.Tb00156.X  0.356
1987 Allan AM, Huidobro-Toro JP, Bleck V, Harris RA. Alcohol and the GABA receptor-chloride channel complex of brain Alcohol and Alcoholism. 643-646. PMID 2447905  0.334
1986 Allan AM, Harris RA. Gamma-aminobutyric acid and alcohol actions: Neurochemical studies of long sleep and short sleep mice Life Sciences. 39: 2005-2015. PMID 3784767 DOI: 10.1016/0024-3205(86)90324-3  0.383
1985 Bylund DB, Solomon N, Ray-Prenger C, Jones SB, Harris RA. Comparison of adrenergic receptor binding in blood cells from alcoholics and controls. Alcohol (Fayetteville, N.Y.). 1: 369-72. PMID 6537222 DOI: 10.1016/0741-8329(84)90005-3  0.366
1985 Mitchell MA, Peris J, Harris RA. Barbiturate tolerance and dependence: effects on synaptosomal sodium transport and membrane fluidity. Pharmacology, Biochemistry, and Behavior. 22: 955-60. PMID 4040639 DOI: 10.1016/0091-3057(85)90302-8  0.319
1984 Harris RA. Defining the membrane pathology produced by chronic alcohol consumption Laboratory Investigation. 50: 113-114. PMID 6694354  0.301
1984 Harris RA, Crabbe JC, McSwigan JD. Relationship of membrane physical properties to alcohol dependence in mice selected for genetic differences in alcohol withdrawal. Life Sciences. 35: 2601-8. PMID 6542619 DOI: 10.1016/0024-3205(84)90027-4  0.55
1983 Yamamoto HA, Harris RA. Calcium-dependent 86Rb efflux and ethanol intoxication: Studies of human red blood cells and rodent brain synaptosomes European Journal of Pharmacology. 88: 357-363. PMID 6861876 DOI: 10.1016/0014-2999(83)90586-1  0.322
1983 Harris RA, Fenner D, Feller D, Sieckman G, Lloyd S, Mitchell M, Dexter JD, Tumbelson ME, Bylund DB. Neurochemical effects of long-term ingestion of ethanol by Sinclair (S-1) swine. Pharmacology, Biochemistry, and Behavior. 18: 363-7. PMID 6132410 DOI: 10.1016/0091-3057(83)90455-0  0.361
1982 Rohde BH, Harris RA. GABA and flunitrazepam binding to neuroblastoma cell membranes--effects of growth conditions, ethanol and pentobarbital. Brain Research. 253: 133-141. PMID 6129916 DOI: 10.1016/0006-8993(82)90680-1  0.313
1980 Snell D, Harris RA. Impairment of avoidance behavior following short-term ingestion of ethanol, tertiary-butanol, or pentobarbital in mice. Psychopharmacology. 69: 53-57. PMID 6771827 DOI: 10.1007/Bf00426521  0.343
1979 Harris RA, Krause W, Goh E, Case J. Behavioral and biochemical effects of chronic consumption of ethanol by hamsters. Pharmacology, Biochemistry, and Behavior. 10: 343-7. PMID 572060 DOI: 10.1016/0091-3057(79)90195-3  0.323
1979 Harris RA, Wu YC, Loh HH. Brain sulfatide and non-lipid sulfate metabolism in leucodystrophic (jimpy) mice. Research Communications in Chemical Pathology and Pharmacology. 25: 377-88. PMID 493721  0.372
1979 Harris RA, Loh HH. Brain sulfatide and non-lipid sulfate metabolism in hypothyroid rats. Research Communications in Chemical Pathology and Pharmacology. 24: 169-79. PMID 432433  0.34
1979 Snell D, Harris RA. Impairment of avoidance behavior following short-term ingestion of alcohol. Psychopharmacology. 63: 251-7. PMID 113811 DOI: 10.1007/BF00433558  0.31
1979 Harris RA, Snell D, Loh HH. Effects of chronic d-amphetamine treatment on schedule-controlled behavior. Psychopharmacology. 63: 55-61. PMID 112622 DOI: 10.1007/Bf00426922  0.357
1978 Huidobro-Toro JP, Harris RA, Loh HH, Way EL. Effects of hypothyroidism on the response of the rat colon to morphine. European Journal of Pharmacology. 52: 191-5. PMID 729631 DOI: 10.1016/0014-2999(78)90205-4  0.515
1978 Iwamoto ET, Harris RA, Loh HH, Way EL. Antinociceptive responses after microinjection of morphine or lanthanum in discrete rat brain sites. The Journal of Pharmacology and Experimental Therapeutics. 206: 46-55. PMID 660557  0.525
1978 Harris RA, Snell D, Loh HH. Effects of d-amphetamine, monomethoxyamphetamines and hallucinogens on schedule-controlled behavior. The Journal of Pharmacology and Experimental Therapeutics. 204: 103-17. PMID 619124  0.343
1978 Yamamoto H, Harris RA, Loh HH, Way EL. Effects of acute and chronic morphine treatments on calcium localization and binding in brain. The Journal of Pharmacology and Experimental Therapeutics. 205: 255-64. PMID 565404  0.533
1978 Law PY, Harris RA, Loh HH, Way EL. Evidence for the involvement of cerebroside sulfate in opiate receptor binding: Studies with Azure A and jimpy mutant mice. The Journal of Pharmacology and Experimental Therapeutics. 207: 458-68. PMID 213557  0.557
1977 Harris RA, Snell D, Loh HH. Stereoselective effects of 1-(2,5-dimethoxy-4-methylphenyl)-2-aminopropane (DOM) on schedule-controlled behavior. Pharmacology, Biochemistry, and Behavior. 7: 307-10. PMID 928488 DOI: 10.1016/0091-3057(77)90225-8  0.329
1977 Harris RA, Snell D, Loh HH, Way EL. Behavioral interactions between naloxone and dopamine agonists. European Journal of Pharmacology. 43: 243-6. PMID 872878 DOI: 10.1016/0014-2999(77)90023-1  0.524
1977 Harris RA, Yamamoto H, Loh HH, Way EL. Discrete changes in brain calcium with morphine analgesia, tolerance-dependence, and abstinence. Life Sciences. 20: 501-5. PMID 557160 DOI: 10.1016/0024-3205(77)90393-9  0.532
1977 Loh HH, Lee NM, Harris RA. Alterations of macromolecule biosynthesis after chronic administration of opiates and ethanol. Advances in Experimental Medicine and Biology. 85: 65-86. PMID 339683  0.459
1977 Yamamoto H, Harris RA, Loh HH, Way EL. Effects of morphine tolerance and dependence on Mg++ dependent ATPase activity of synaptic vesicles. Life Sciences. 20: 1533-9. PMID 141578 DOI: 10.1016/0024-3205(77)90445-3  0.532
1976 Yamamoto HA, Harris RA, Loh HH, Way EL. Calcium binding to brain membranes: effects of morphine tolerance. Proceedings of the Western Pharmacology Society. 19: 71-4. PMID 996029  0.527
1976 Harris RA, Loh HH, Way EL. Alterations in the efficacy of naloxone induced by stress, cyclic adenosine monophosphate, and morphine tolerance. European Journal of Pharmacology. 39: 1-10. PMID 183962 DOI: 10.1016/0014-2999(76)90107-2  0.53
1976 Harris RA, Loh HH, Way EL. Antinociceptive effects of lanthanum and cerium in nontolerant and morphine tolerant-dependent animals. The Journal of Pharmacology and Experimental Therapeutics. 196: 288-97. PMID 176345  0.544
1975 Harris RA, Loh HH, Way EL. Effects of divalent cations, cation chelators and an ionophore on morphine analgesia and tolerance. The Journal of Pharmacology and Experimental Therapeutics. 195: 488-98. PMID 1195132  0.53
1975 Harris RA, Iwamoto ET, Loh HH, Way EL. Analgetic effects of lanthanum: cross-tolerance with morphine. Brain Research. 100: 221-5. PMID 1182518 DOI: 10.1016/0006-8993(75)90264-4  0.503
1975 Harris RA, Iwamoto ET, Loh HH, Way EL. Site dependent analgesia after microinjection of morphine or lanthanum in rat brain. Proceedings of the Western Pharmacology Society. 18: 275-8. PMID 1178680  0.526
1975 Loh HH, Cho TM, Wu YC, Harris RA, Way EL. Opiate binding to cerebroside sulfate: a model system for opiate-receptor interaction. Life Sciences. 16: 1811-7. PMID 1152609 DOI: 10.1016/0024-3205(75)90281-7  0.572
1975 Harris RA, Harris LS, Dunn A. Effect of narcotic drugs on ribonucleic acid and nucleotide metabolism in mouse brain. The Journal of Pharmacology and Experimental Therapeutics. 192: 280-7. PMID 1117416  0.414
1974 Kosersky DS, Harris RA, Harris LS. Naloxone-precipitated jumping activity in mice following the acute administration of morphine. European Journal of Pharmacology. 26: 122-4. PMID 4857602 DOI: 10.1016/0014-2999(74)90084-3  0.41
1974 Harris RA, Dunn A, Harris LS. Effects of acute and chronic morphine administration on the incorporation of (3H)-lysine into mouse brain and liver proteins. Research Communications in Chemical Pathology and Pharmacology. 9: 299-306. PMID 4438835  0.418
1972 McMillan DE, Ford RD, Frankenheim JM, Harris RA, Harris LS. Tolerance to active constituents of marihuana. Archives Internationales De Pharmacodynamie Et De Thã©Rapie. 198: 132-44. PMID 5053235  0.369
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